Maurizio Guida, Luciano Quercitelli, Pasquale De Franciscis, Cinzia Ferrara, Marco Marietta, Mattia Iaccheri, Fabio Facchinetti, Filomena Capasso, Giovanni Grandi
PURPOSE: Progestin-only pills (POPs), compared to combined, are not associated with an increased risk of venous thromboembolism, but are associated with a poor cycle control. The aim of this study was to evaluate the impact of a new POP [4 mg drospirenone (DRSP) for 24 days with a 4-day hormone-free interval] on some coagulation markers (both procoagulant and fibrinolytic) and to describe its impact on bleeding patterns. MATERIALS AND METHODS: This is a prospective trial, based on serum evaluation of following coagulation markers and tests: Factor (F) X, F VIII, F V, INR, aPTT, Protein S and antithrombin III...
December 2023: European Journal of Contraception & Reproductive Health Care