Jacqueline A Piekos, Jeewoo Kim, Jacob M Keaton, Jacklyn N Hellwege, Todd L Edwards, Digna R Velez Edwards
There is a desire in research to move away from the concept of race as a clinical factor because it is a societal construct used as an imprecise proxy for geographic ancestry. In this study, we leverage the biobank from Vanderbilt University Medical Center, BioVU, to investigate relationships between genetic ancestry proportion and the clinical phenome. For all samples in BioVU, we calculated six ancestry proportions based on 1000 Genomes references: eastern African (EAFR), western African (WAFR), northern European (NEUR), southern European (SEUR), eastern Asian (EAS), and southern Asian (SAS)...
2024: Pacific Symposium on Biocomputing