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Oral Oncology

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https://www.readbyqxmd.com/read/30206013/-meditation-training-intervention-a-necessary-shift-for-head-and-neck-cancer-patients
#1
LETTER
Prashanth Panta
No abstract text is available yet for this article.
September 8, 2018: Oral Oncology
https://www.readbyqxmd.com/read/30201513/corrigendum-to-the-role-of-protein-methyltransferases-as-potential-novel-therapeutic-targets-in-squamous-cell-carcinoma-of-the-head-and-neck-oral-oncol-81-2018-100-108
#2
Vassiliki Saloura, Theodore Vougiouklakis, Kyunghee Burkitt, Yusuke Nakamura, Gordon L Hager, Carter van Waes
No abstract text is available yet for this article.
September 7, 2018: Oral Oncology
https://www.readbyqxmd.com/read/30174204/-chronic-traumatic-ulcer-of-lateral-tongue-an-underestimated-oral-potentially-malignant-disorder
#3
LETTER
Prashanth Panta, Sachin C Sarode, Gargi S Sarode, Shankargouda Patil
No abstract text is available yet for this article.
August 30, 2018: Oral Oncology
https://www.readbyqxmd.com/read/30154040/chronic-hepatitis-c-virus-infection-in-patients-with-nonoropharyngeal-head-and-neck-cancers
#4
LETTER
Georgios Angelidakis, Erich M Sturgis, Minas P Economides, Ying Jiang, Harrys A Torres
No abstract text is available yet for this article.
August 25, 2018: Oral Oncology
https://www.readbyqxmd.com/read/30122290/can-healthy-diet-intercept-progression-of-oral-potentially-malignant-disorders
#5
LETTER
Prashanth Panta, Sachin C Sarode, Gargi S Sarode, Shankargouda Patil
No abstract text is available yet for this article.
August 17, 2018: Oral Oncology
https://www.readbyqxmd.com/read/30098877/low-level-laser-therapy-reduces-oral-leukoplakia-lesion-size-results-from-a-preliminary-study
#6
LETTER
Bhagyashree Jagtap, Kalyani Bhate, S N Santhoshkumar
No abstract text is available yet for this article.
August 8, 2018: Oral Oncology
https://www.readbyqxmd.com/read/30087003/flavored-tobacco-to-e-cigarette-s-how-the-tobacco-industry-sustains-its-product-flow
#7
LETTER
A Thirumal Raj, Shankargouda Patil, Archana A Gupta, G Suveetha
No abstract text is available yet for this article.
August 4, 2018: Oral Oncology
https://www.readbyqxmd.com/read/30220326/the-efficacy-of-induction-chemotherapy-in-the-treatment-of-stage-ii-nasopharyngeal-carcinoma-in-intensity-modulated-radiotherapy-era
#8
Pei-Jing Li, Hao-Yuan Mo, Dong-Hua Luo, Wei-Han Hu, Ting Jin
PURPOSE: To evaluate the efficacy of induction chemotherapy in the treatment of stage II nasopharyngeal carcinoma (NPC) in era of intensity modulated radiotherapy (IMRT). METHODS AND MATERIALS: A total of 173 patients with American Joint Committee on Cancer (AJCC) 7th stage II NPC from two institutions were included. All patients were divided into two groups: induction chemotherapy + concurrent chemoradiotherapy group (ICRT) group and concurrent chemoradiotherapy group (CCRT)...
October 2018: Oral Oncology
https://www.readbyqxmd.com/read/30220325/dna-methylation-derived-systemic-inflammation-indices-are-associated-with-head-and-neck-cancer-development-and-survival
#9
Srikant Ambatipudi, Ryan Langdon, Rebecca C Richmond, Matthew Suderman, Devin C Koestler, Karl T Kelsey, Nabila Kazmi, Christopher Penfold, Karen M Ho, Wendy McArdle, Susan M Ring, Miranda Pring, Tim Waterboer, Michael Pawlita, Tom R Gaunt, George Davey Smith, Steve Thomas, Andy R Ness, Caroline L Relton
OBJECTIVES: Head and neck squamous cell carcinoma (HNSCC) is often associated with chronic systemic inflammation (SI). In the present study, we assessed if DNA methylation-derived SI (mdSI) indices: Neutrophil-to-Lymphocyte ratio (mdNLR) and Lymphocyte-to-Monocyte ratio (mdLMR) are associated with the presence of HNSCC and overall survival (OS). MATERIALS AND METHODS: We used two peripheral blood DNA methylation datasets: an HNSCC case-control dataset (n = 183) and an HNSCC survival dataset (n = 407) to estimate mdSI indices...
October 2018: Oral Oncology
https://www.readbyqxmd.com/read/30220324/prognostic-implications-of-the-8th-edition-american-joint-committee-on-cancer-ajcc-staging-system-in-oral-cavity-squamous-cell-carcinoma
#10
Nikolaus Moeckelmann, Ardalan Ebrahimi, Ying K Tou, Ruta Gupta, Tsu-Hui Hubert Low, Bruce Ashford, Sydney Ch'ng, Carsten E Palme, Jonathan R Clark
BACKGROUND: The American Joint Committee on Cancer (AJCC) has changed the staging system of oral squamous cell carcinoma (OSCC) in the 8th edition of its staging manual to include depth of invasion (DOI) of the primary tumor as a modifier to the T category and extranodal extension (ENE) to upstage node positive OSCC. This study aims to evaluate the performance of the AJCC 8 pathologic staging system in OSCC and compare it to its predecessor (AJCC 7). METHODS: Analysis of 663 patients with OSCC from a prospective database was performed using the Cox proportional hazards competing risk model...
October 2018: Oral Oncology
https://www.readbyqxmd.com/read/30220323/temporal-lobe-injury-patterns-following-intensity-modulated-radiotherapy-in-a-large-cohort-of-nasopharyngeal-carcinoma-patients
#11
Lixia Lu, Yang Sheng, Guangshun Zhang, Yizhuo Li, Pu-Yun OuYang, Yaorong Ge, Tianyi Xie, Hui Chang, Xiaowu Deng, Jackie Q Wu
OBJECTIVES: To analyze the correlation between dose-volume-histograms (DVHs) with three patterns (edema, enhancement, and necrosis) of temporal lobe injury (TLI) in patients receiving intensity modulated radiation therapy (IMRT) for nasopharyngeal carcinoma (NPC) and to determine optimal thresholds to predict the incidence of each TLI pattern, with particular emphasis on the relationship between edema volume and the risk of enhancement and necrosis. MATERIALS AND METHODS: A cohort of 4186 NPC patients treated with IMRT was retrospectively reviewed with TLI presenting in 188 patients...
October 2018: Oral Oncology
https://www.readbyqxmd.com/read/30220322/protective-effects-of-metformin-statins-and-anti-inflammatory-drugs-on-head-and-neck-cancer-a-systematic-review
#12
REVIEW
Constanza Saka Herrán, Enric Jané-Salas, Albert Estrugo Devesa, José López-López
The main objective of this study was to evaluate the effect of metformin, statins and anti-inflammatory drugs (NSAIDs) on head and neck cancer (HNC). Specifically, the potential beneficial effects on risk, survival and recurrence based on epidemiological studies. PRISMA guidelines were followed. After searching MEDLINE (PubMed), IBECS, LILACS and the Cochrane Central Register for Controlled Trials, 13 studies met the inclusion criteria and so underwent qualitative synthesis (six studies for metformin and seven for NSAIDs)...
October 2018: Oral Oncology
https://www.readbyqxmd.com/read/30220321/clinical-perineural-invasion-of-cutaneous-head-and-neck-cancer-impact-of-radiotherapy-imaging-and-nerve-growth-factor-receptors-on-symptom-control-and-prognosis
#13
Jie Jane Chen, Jeremy P Harris, Christina S Kong, John B Sunwoo, Vasu Divi, Kathleen C Horst, Sumaira Z Aasi, S Tyler Hollmig, Wendy Y Hara
OBJECTIVES: Clinical perineural invasion (CPNI) of cutaneous head and neck cancer is associated with poor prognosis and presents a therapeutic dilemma. The purpose of this study was to determine the relationship between CPNI and nerve growth factor receptors (NGFR), and the impact of radiotherapy (RT), imaging, and NGFR on symptom control and disease-related outcomes. MATERIALS AND METHODS: We retrospectively reviewed patients with CPNI of cutaneous head and neck cancer who were treated with RT between 2010 and 2015 at our institution...
October 2018: Oral Oncology
https://www.readbyqxmd.com/read/30220320/odontogenic-carcinosarcoma-a-systematic-review
#14
REVIEW
Lauren Frenzel Schuch, José Alcides Almeida de Arruda, Leni Verônica Oliveira Silva, Lucas Guimarães Abreu, Tarcília Aparecida Silva, Ricardo Alves Mesquita
The aim of this study was to integrate the available data published on odontogenic carcinosarcoma into a comprehensive analysis of their features, treatment and recurrence. An electronic search with no publication date or language restriction was undertaken in March 2018 in the following databases: Medline Ovid, PubMed, Web of Science, Scopus and LILACS. Eligibility criteria included publications having enough clinical, imaginological and histopathological information to confirm a definite diagnosis of the neoplasm...
October 2018: Oral Oncology
https://www.readbyqxmd.com/read/30220319/three-distinct-genomic-subtypes-of-head-and-neck-squamous-cell-carcinoma-associated-with-clinical-outcomes
#15
Dong Jin Lee, Young-Gyu Eun, Young Soo Rho, Eui Hyun Kim, Sun Young Yim, Sang Hee Kang, Bo Hwa Sohn, Gee Hwan Kwon, Ju-Seog Lee
OBJECTIVES: Heterogeneity of head and neck squamous cell carcinomas (HNSCCs) results in unpredictable outcomes for patients with similar stages of cancer. Beyond the role of human papilloma virus (HPV), no validated molecular marker of HNSCCs has been established. Thus, clinically relevant molecular subtypes are needed to optimize HNSCC therapy. The purpose of this study was to identify subtypes of HNSCC that have distinct biological characteristics associated with clinical outcomes and to characterize genomic alterations that best reflect the biological and clinical characteristics of each subtype...
October 2018: Oral Oncology
https://www.readbyqxmd.com/read/30220318/the-impact-of-institutional-clinical-trial-recruitment-versus-hospital-volume-on-survival-outcomes-of-patients-with-head-and-neck-cancer-an-analysis-of-the-pet-neck-trial-outcomes-ukcrn-portfolio-and-hospital-episode-statistics-hes-in-england
#16
Daniel J Lin, Christopher C McConkey, Paul Nankivell, Janet Dunn, Hisham Mehanna
OBJECTIVES: High institutional clinical trial recruitment and high hospital volume are reported to be independent indicators of better patient outcomes following cancer treatment. However, their relationship in head and neck cancers (HNC) remains less clear. METHODS: We aimed to assess the relationship between institutional clinical trial recruitment, hospital throughput of HNC cases, and survival of patients with advanced HNC treated with primary chemoradiotherapy at hospitals which recruited to the PET-NECK trial (2008-2012)...
October 2018: Oral Oncology
https://www.readbyqxmd.com/read/30220317/patterns-of-failure-in-high-metastatic-node-number-human-papillomavirus-positive-oropharyngeal-carcinoma
#17
Nicholas C J Lee, Jacqueline R Kelly, Henry S Park, Yi An, Benjamin L Judson, Barbara A Burtness, Zain A Husain
BACKGROUND: The 8th edition American Joint Committee on Cancer staging system for resected HPV-positive oropharynx carcinoma (HPV+ OPC) highlights high node number as a critical determinant of survival. We sought to characterize outcomes and patterns of failure in patients with high pathologically involved node number oropharynx cancer. METHODS: We retrospectively identified 116 HPV+ OPC patients sequentially treated with neck dissection and either resection or intraoperative brachytherapy of the primary tumor between 2010 and 2016...
October 2018: Oral Oncology
https://www.readbyqxmd.com/read/30220316/radiologic-predictors-of-immune-checkpoint-inhibitor-response-in-advanced-head-and-neck-squamous-cell-carcinoma
#18
Vishwajith Sridharan, Rifaquat M Rahman, Raymond Y Huang, Nicole G Chau, Jochen H Lorch, Ravindra Uppaluri, Robert I Haddad, Glenn J Hanna, Jonathan D Schoenfeld
Radiologic predictors of response to immune checkpoint blockade (ICPi) in advanced head and neck squamous cell carcinoma (HNSCC) patients could help guide patient selection and management. We analyzed a large institutional cohort of 100 consecutive HNSCC patients treated with ICPi to investigate associations between molecular and radiologic phenotype and assess radiologic predictors of response and survival. Of particular interest was the impact of increased total tumor burden (TB), calculated as the sum of the largest diameter of all measurable lesions according to RECIST 1...
October 2018: Oral Oncology
https://www.readbyqxmd.com/read/30220315/the-spider-limb-positioner-in-subscapular-system-free-flaps
#19
Jayne R Stevens, Andrew J Rosko, Emily Marchiano, Cate Haring, Steven B Chinn, Kelly M Malloy, Mark E Prince, Keith Casper, Jeffrey Moyer, Douglas Chepeha, Chaz L Stucken, Matthew E Spector
BACKGROUND: The subscapular system is a versatile vascular network that can provide multiple flaps for reconstruction of the head and neck. A significant drawback of using the subscapular system is that patient positioning can preclude the use of simultaneous two-team ablative and reconstructive surgery. Herein, we describe a novel use of an upper extremity limb positioner (Spider Limb Positioner) used primarily in orthopedic surgery to facilitate concurrent two-team technique in head and neck surgery...
October 2018: Oral Oncology
https://www.readbyqxmd.com/read/30220314/risk-reductive-dental-strategies-for-medication-related-osteonecrosis-of-the-jaw-among-cancer-patients-a-systematic-review-with-meta-analyses
#20
REVIEW
Harry Karna, Jaime Gonzalez, Harveen S Radia, Parish P Sedghizadeh, Reyes Enciso
The purpose of this systematic review with meta-analysis was to assess the effectiveness of dental interventions in preventing or reducing the incidence of medication-related osteonecrosis of the jaw (MRONJ) in cancer patients receiving antiresorptive therapy, compared to similar control groups receiving no intervention. Randomized controlled trials (RCT), case-controls and cohorts on cancer patients with primary outcome being the prevalence of MRONJ were included. Four electronic databases were searched (Cochrane Library, PubMed, EMBASE and Web of Science) up to February 12, 2018...
October 2018: Oral Oncology
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