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Oral Oncology

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https://www.readbyqxmd.com/read/28916260/primary-facial-reanimation-in-head-and-neck-cancer
#1
REVIEW
Axel Sahovaler, David Yeh, John Yoo
Facial Paralysis (FP) profoundly impairs the life of individuals, both functionally and psychosocially. Surgical approaches to treat this condition are myriad, but the ultimate goal is to restore symmetry and movement. Ablative surgery for tumors of the head and neck region are amongst the most common etiologies causing FP and this group of patients represents unique challenges. Surgical defects may have multiple competing reconstructive requirements and addressing the FP must be considered in this context...
September 12, 2017: Oral Oncology
https://www.readbyqxmd.com/read/28789828/the-difficult-management-of-radio-incuced-head-and-neck-sarcomas
#2
LETTER
Valentina Terenzi, Andrea Cassoni, Marco Della Monaca, Giulia Di Benedetto, Paolo Priore, Andrea Battisti, Valentino Valentini
No abstract text is available yet for this article.
August 5, 2017: Oral Oncology
https://www.readbyqxmd.com/read/28743467/basal-cell-adenocarcinoma-of-the-skull-base-a-diagnostic-challenge
#3
LETTER
Zachary A Zimmerman, John Shapiro, C Arturo Solares, Paul Biddinger, James K Byrd
No abstract text is available yet for this article.
July 22, 2017: Oral Oncology
https://www.readbyqxmd.com/read/28743466/corrigendum-to-orthotopic-non-metastatic-and-metastatic-oral-cancer-mouse-models-oral-oncol-51-5-2015-476-482
#4
Manish V Bais, Maria Kukuruzinska, Philip C Trackman
No abstract text is available yet for this article.
July 22, 2017: Oral Oncology
https://www.readbyqxmd.com/read/28739194/perforator-based-rectus-free-tissue-transfer-for-head-and-neck-reconstruction-new-reconstructive-advantages-from-an-old-friend
#5
Stephen Y Kang, Matthew E Spector, Douglas B Chepeha
OBJECTIVES: To demonstrate three reconstructive advantages of the perforator based rectus free tissue transfer: long pedicle, customizable adipose tissue, and volume reconstruction without muscle atrophy within a contained space. MATERIALS AND METHODS: Thirty patients with defects of the head and neck were reconstructed with the perforator based rectus free tissue transfer. RESULTS: Transplant success was 93%. Mean pedicle length was 13.4cm...
July 21, 2017: Oral Oncology
https://www.readbyqxmd.com/read/28720420/transoral-robotic-total-laryngopharyngectomy-and-free-jejunal-flap-reconstruction-for-hypopharyngeal-cancer
#6
LETTER
Jimmy Yu Wai Chan, Richie Chiu Lung Chan, Velda Ling Yu Chow, Raymond King Ying Tsang, Stanley Thian Sze Wong, William Ignace Wei
BACKGROUND: To report on the feasibility of total laryngopharyngectomy and free jejunal flap transfer for patient with hypopharyngeal cancer via the transoral robotic surgery (TORS) approach. MATERIAL AND METHODS: A patient with hypopharyngeal cancer involving the post-cricoid region is used for demonstration of the TORS total laryngopharyngectomy and free jejunal flap reconstruction. RESULTS: The procedure starts with a cruciate incision for terminal tracheostomy...
July 15, 2017: Oral Oncology
https://www.readbyqxmd.com/read/28711305/corrigendum-to-microrna-17-20a-functions-to-inhibit-cell-migration-and-can-be-used-a-prognostic-marker-in-oral-squamous-cell-carcinoma-oral-oncol-49-9-2013-923-931
#7
Cheng-Chi Chang, Yu-Jen Yang, Yue-Ju Li, Szu-Ta Chen, Been-Ren Lin, Tai-Sheng Wu, Sze-Kwen Lin, Mark Yen-Ping Kuo, Ching-Ting Tan
No abstract text is available yet for this article.
July 12, 2017: Oral Oncology
https://www.readbyqxmd.com/read/28688607/will-the-8th-editions-of-the-uicc-ajcc-staging-manuals-improve-the-pathological-diagnosis-of-extranodal-extension-from-cervical-lymph-nodes
#8
LETTER
Andrew W Barrett
No abstract text is available yet for this article.
July 5, 2017: Oral Oncology
https://www.readbyqxmd.com/read/28673692/combination-of-docetaxel-trastuzumab-and-pertuzumab-or-treatment-with-trastuzumab-emtansine-for-metastatic-salivary-duct-carcinoma
#9
LETTER
Wim van Boxtel, Eline Boon, Willem L J Weijs, Frank J A van den Hoogen, Uta E Flucke, Carla M L van Herpen
No abstract text is available yet for this article.
June 30, 2017: Oral Oncology
https://www.readbyqxmd.com/read/28669748/reduction-of-severe-oropharyngeal-hemorrhage-following-transoral-robotic-surgery
#10
EDITORIAL
Matthew Old
No abstract text is available yet for this article.
June 29, 2017: Oral Oncology
https://www.readbyqxmd.com/read/28668299/head-neck-reconstruction-predictors-of-readmission
#11
Evan M Graboyes, Joseph Zenga, Brian Nussenbaum
Unplanned hospital readmission following head and neck cancer surgery is common and associated with significant negative consequences. Because of the vital role that microvascular free tissue transfer plays in the management of head and neck oncologic defects, its relationship to unplanned hospital readmission requires attention. In this review, the incidence of, risk factors for, and reasons for unplanned readmission in patients undergoing free flap reconstruction for head and neck cancer are analyzed. The role of free flap reconstruction as a separate risk factor for unplanned readmission in patients with head and neck cancer is described...
June 28, 2017: Oral Oncology
https://www.readbyqxmd.com/read/28797468/incidence-of-and-risk-factors-for-mandibular-osteoradionecrosis-in-patients-with-oral-cavity-and-oropharynx-cancers
#12
Dominic H Moon, Sung Ho Moon, Kyle Wang, Mark C Weissler, Trevor G Hackman, Adam M Zanation, Brian D Thorp, Samip N Patel, Jose P Zevallos, Lawrence B Marks, Bhishamjit S Chera
OBJECTIVES: To evaluate the incidence of, and risk factors associated with, mandibular osteoradionecrosis (MORN) following radiation therapy (RT) for oral cavity and oropharyngeal cancers. MATERIALS AND METHODS: Patient and treatment records of 252 consecutive patients with oral cavity or oropharynx cancers treated with RT by a single radiation oncologist at a high volume academic institution from August 2009 to December 2015 were retrospectively reviewed. A Cox regression model was used to assess factors associated with the development of MORN...
September 2017: Oral Oncology
https://www.readbyqxmd.com/read/28797467/outcomes-of-oral-cavity-cancer-patients-treated-with-surgery-followed-by-postoperative-intensity-modulated-radiation-therapy
#13
Sean R Quinlan-Davidson, Abdallah S R Mohamed, Jeffrey N Myers, Gary B Gunn, Faye M Johnson, Heath Skinner, Beth M Beadle, Ann M Gillenwater, Jack Phan, Steven J Frank, William N William, Andrew J Wong, Stephen Y Lai, Clifton D Fuller, William H Morrison, David I Rosenthal, Adam S Garden
OBJECTIVES: Although treatment paradigms have not changed significantly, radiotherapy, surgery, and imaging techniques have improved, leading us to investigate oncologic and survival outcomes for oral cavity squamous cell cancer (OCSCC) patients treated with surgery followed by postoperative IMRT. MATERIAL AND METHODS: Records of patients with pathological diagnosis of OCSCC treated between 2000 and 2012 were retrospectively reviewed. Patients' demographic, disease, and treatment criteria were extracted...
September 2017: Oral Oncology
https://www.readbyqxmd.com/read/28797466/trials-in-head-and-neck-oncology-evolution-of-perioperative-adjuvant-therapy
#14
REVIEW
Joseph Zenga, Patrik Pipkorn, Douglas R Adkins, Wade L Thorstad, Brian Nussenbaum
No abstract text is available yet for this article.
September 2017: Oral Oncology
https://www.readbyqxmd.com/read/28797465/conditional-relative-survival-of-oral-cavity-cancer-based-on-korean-central-cancer-registry
#15
Seung-Ki Min, Sung Weon Choi, Johyun Ha, Joo Yong Park, Young-Joo Won, Kyu-Won Jung
OBJECTIVES: Conditional relative survival (CRS) describes the survival chance of patients who have already survived for a certain period of time after diagnosis and treatment of cancer. Thus, CRS can complement the conventional 5-year relative survival, which does not consider the time patients have survived after their diagnosis. This study aimed to assess the 5-year CRS among Korean patients with oral cancer and the related risk factors. MATERIALS AND METHODS: We identified 15,329 oral cavity cancer cases with a diagnosis between 1993 and 2013 in the Korea Central Cancer Registry...
September 2017: Oral Oncology
https://www.readbyqxmd.com/read/28797464/relevance-of-chromosomal-band-11q13-in-oral-carcinogenesis-an-update-of-current-knowledge
#16
REVIEW
Pablo Ramos-García, Isabel Ruiz-Ávila, José Antonio Gil-Montoya, Ángela Ayén, Lucía González-Ruiz, Francisco José Navarro-Triviño, Miguel Ángel González-Moles
An important event in oral carcinogenesis is the amplification of chromosomal band 11q13, in which numerous oncogenes and some tumor-suppressor genes are localized and frequently co-amplified during the malignant transformation of oral epithelium. The objectives of this study were to review published data on the involvement of 11q13 amplification in oral cancer, to provide an update on novel concepts and terminology related to gene amplification, and to explore the composition of the 11q13 amplicon in OSCC, including its most relevant amplicon cores and potential drivers...
September 2017: Oral Oncology
https://www.readbyqxmd.com/read/28797463/validation-and-comparison-of-the-7th-and-8th-edition-of-ajcc-staging-systems-for-non-metastatic-nasopharyngeal-carcinoma-and-proposed-staging-systems-from-hong-kong-guangzhou-and-guangxi
#17
Pu-Yun OuYang, Yao Xiao, Kai-Yun You, Lu-Ning Zhang, Xiao-Wen Lan, Xiao-Min Zhang, Fang-Yun Xie
OBJECTIVES: We aimed to validate and compare the 7th and 8th edition of AJCC staging systems for non-metastatic nasopharyngeal carcinoma, and proposed staging systems from Hong Kong, Guangzhou, and Guangxi. MATERIALS AND METHODS: We retrospectively included 899 patients treated between November 5, 2002 and May 27, 2010. Separation and discrimination of each staging system in overall survival were primarily compared. RESULTS: Compared with the 7th AJCC, the 8th AJCC and all proposed staging systems well separated across T-classification...
September 2017: Oral Oncology
https://www.readbyqxmd.com/read/28797462/a-comprehensive-study-of-smoking-specific-microrna-alterations-in-head-and-neck-squamous-cell-carcinoma
#18
Aswini R Krishnan, Hao Zheng, James G Kwok, Yuanhao Qu, Angela E Zou, Avinaash Korrapati, Pin Xue Li, Joseph A Califano, Melbourne F Hovell, Jessica Wang-Rodriguez, Weg M Ongkeko
OBJECTIVE: While tobacco smoking is a well-known risk factor for head and neck squamous cell carcinoma (HNSCC), the molecular mechanisms underlying tobacco-induced HNSCC remain unclear. This study sought to comprehensively identify microRNA (miRNA) alterations and evaluate their clinical relevance in smoking-induced HNSCC pathogenesis and progression. MATERIALS AND METHODS: Using small RNA-sequencing data and clinical data from 145 HNSCC patients, we performed a series of differential expression and correlation analyses to identify a panel of tobacco-dysregulated miRNAs associated with key clinical characteristics in HNSCC...
September 2017: Oral Oncology
https://www.readbyqxmd.com/read/28797461/the-importance-of-log-odds-of-positive-lymph-nodes-for-locoregional-recurrence-in-oral-squamous-cell-carcinoma
#19
Ali-Farid Safi, Martin Kauke, Andrea Grandoch, Hans-Joachim Nickenig, Uta Drebber, Joachim Zöller, Matthias Kreppel
OBJECTIVES: Log odds of positive lymph nodes (LODDS) has been demonstrated as a very promising staging model for multiple cancer sites, as it avoids singularity and predicts prognosis significantly better than conventional nodal staging and lymph node ratio. However, published studies on the influence of LODDS for patients with OSCC are very seldom. MATERIAL AND METHODS: Retrospective chart review of 499 patients with treatment-naive oral squamous cell carcinoma...
September 2017: Oral Oncology
https://www.readbyqxmd.com/read/28797460/prognostic-biomarkers-in-oral-squamous-cell-carcinoma-a-systematic-review
#20
REVIEW
César Rivera, Ana Karina Oliveira, Rute Alves Pereira Costa, Tatiane De Rossi, Adriana Franco Paes Leme
Over the years, several tumor biomarkers have been suggested to foresee the prognosis oral squamous cell carcinoma (OSCC) patients. Here, we present a systematic review to identify, evaluate and summarize the evidence for OSCC reported markers. Eligible studies were identified through a literature search of MEDLINE/PubMed until January 2016. We included primary articlesreporting overall survival, disease-free survival and cause-specific survival as outcomes. Our findings were analysed using REporting recommendations for tumor MARKer prognostic studies (REMARK), QuickGo tool and SciCurve trends...
September 2017: Oral Oncology
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