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Oral Oncology

Jimmy Yu Wai Chan, Richie Chiu Lung Chan, Velda Ling Yu Chow, Raymond King Ying Tsang, Stanley Thian Sze Wong, William Ignace Wei
BACKGROUND: To report on the feasibility of total laryngopharyngectomy and free jejunal flap transfer for patient with hypopharyngeal cancer via the transoral robotic surgery (TORS) approach. MATERIAL AND METHODS: A patient with hypopharyngeal cancer involving the post-cricoid region is used for demonstration of the TORS total laryngopharyngectomy and free jejunal flap reconstruction. RESULTS: The procedure starts with a cruciate incision for terminal tracheostomy...
July 15, 2017: Oral Oncology
Cheng-Chi Chang, Yu-Jen Yang, Yue-Ju Li, Szu-Ta Chen, Been-Ren Lin, Tai-Sheng Wu, Sze-Kwen Lin, Mark Yen-Ping Kuo, Ching-Ting Tan
No abstract text is available yet for this article.
July 12, 2017: Oral Oncology
Andrew W Barrett
No abstract text is available yet for this article.
July 5, 2017: Oral Oncology
Wim van Boxtel, Eline Boon, Willem L J Weijs, Frank J A van den Hoogen, Uta E Flucke, Carla M L van Herpen
No abstract text is available yet for this article.
June 30, 2017: Oral Oncology
Matthew Old
No abstract text is available yet for this article.
June 29, 2017: Oral Oncology
Evan M Graboyes, Joseph Zenga, Brian Nussenbaum
Unplanned hospital readmission following head and neck cancer surgery is common and associated with significant negative consequences. Because of the vital role that microvascular free tissue transfer plays in the management of head and neck oncologic defects, its relationship to unplanned hospital readmission requires attention. In this review, the incidence of, risk factors for, and reasons for unplanned readmission in patients undergoing free flap reconstruction for head and neck cancer are analyzed. The role of free flap reconstruction as a separate risk factor for unplanned readmission in patients with head and neck cancer is described...
June 28, 2017: Oral Oncology
A Thirumal Raj
No abstract text is available yet for this article.
May 27, 2017: Oral Oncology
Anuradha Chougule, Vijay M Patil, Vanita Noronha, Amit Joshi, Siddharth Turkkar, Arun Chandrasekharan, Nikhil Pande, Priyanka Bagayatkar, Kumar Prabhash
No abstract text is available yet for this article.
May 22, 2017: Oral Oncology
Nadia Camille, John Rozehnal, Elizabeth Roy, Dariusz Uczkowski, Ashely Olson, Eric Genden, Marita Teng, Richard Bakst, Vishal Gupta, Marshall Posner, Krzysztof Misiukiewicz
BACKGROUND: There is a clinical need to improve outcomes for patients with locally advanced squamous cell carcinoma of the head and neck (LA-SCCHN), especially in Human Papilloma Virus (HPV) negative and HPV positive subtypes with a significant history of tobacco use. In animal models bearing SCCHN, Cabazitaxel showed an excellent response rate compared to docetaxel and might prove useful in treatment of patients. The primary objective of this study was to determine the dose-limiting toxicity (DLT) and maximum tolerated dose (MTD) of cabazitaxel when combined with cisplatin and 5-fluorouracil (PF) in induction chemotherapy (IC) for patients with SCCHN...
August 2017: Oral Oncology
Özgün Özçaka, Joel B Epstein, Pelin Güneri
No abstract text is available yet for this article.
August 2017: Oral Oncology
Megan Morisada, Ellen C Moore, Rachel Hodge, Jay Friedman, Harrison A Cash, James W Hodge, James B Mitchell, Clint T Allen
OBJECTIVES: Determine if direct tumor cell cytotoxicity, antigen release, and susceptibility to T-lymphocyte killing following radiation treatment is dose-dependent. MATERIALS AND METHODS: Mouse oral cancer cells were engineered to express full-length ovalbumin as a model antigen. Tumor antigen release with uptake and cross presentation of antigen by antigen presenting cells with subsequent priming and expansion of antigen-specific T-lymphocytes following radiation was modeled in vitro and in vivo...
August 2017: Oral Oncology
Tae Hyuk Kim, Young Nam Kim, Hye In Kim, So Young Park, Jun-Ho Choe, Jung-Han Kim, Jee Soo Kim, Young Lyun Oh, Soo Yeon Hahn, Jung Hee Shin, Kyunga Kim, Jong Gill Jeong, Sun Wook Kim, Jae Hoon Chung
BACKGROUND: The prognostic value of the proposed eighth edition of the American Joint Committee on Cancer (AJCC) tumor, node, and metastasis (TNM) classification is currently unclear. The aim of the study was to evaluate the prognostic value of the eighth edition of the AJCC TNM classification. METHODS: We retrospectively assessed 3176 patients with differentiated thyroid carcinoma (DTC) who underwent thyroidectomy at a tertiary Korean hospital from 1996 to 2005...
August 2017: Oral Oncology
Jonathon O Russell, James Clark, Salem I Noureldine, Angkoon Anuwong, Mai G Al Khadem, Hoon Yub Kim, Vaninder K Dhillon, Gianlorenzo Dionigi, Ralph P Tufano, Jeremy D Richmon
OBJECTIVE: Most thyroid surgery in North America is completed via a cervical incision, which leaves a permanent scar. Approaches without cutaneous incisions offer aesthetic advantages. This series represents the largest series of transoral vestibular approaches to the central neck in North America, and the first published reports of robotic transoral vestibular thyroidectomy for thyroid carcinoma. MATERIALS AND METHODS: Data was prospectively collected for patients that underwent transoral vestibular approach thyroidectomy and/or parathyroidectomy between April 2016 and February 2017...
August 2017: Oral Oncology
L Arribas, L Hurtós, M Taberna, I Peiró, E Vilajosana, A Lozano, S Vazquez, R Mesia, N Virgili
OBJECTIVE: The purpose of the study is to evaluate changes in body composition and nutritional status that occur throughout the oncological treatment in head and neck cancer patients. METHODS: A prospective cohort observational study in patients diagnosed with head and neck squamous cell carcinoma (HNSCC) that underwent treatment with induction chemotherapy (iCT) followed by chemoradiotherapy or bioradiotherapy were invited to participate. All patients had dietetic counseling from the diagnosis and a close monitoring throughout the treatment implementing nutritional support as needed...
August 2017: Oral Oncology
Yungan Tao, Anne Aupérin, Pierre Graff, Michel Lapeyre, Vincent Grégoire, Philippe Maingon, Lionel Geoffrois, Pierre Verrelle, Gilles Calais, Bernard Gery, Laurent Martin, Marc Alfonsi, Patrick Deprez, Etienne Bardet, Thierry Pignon, Michel Rives, Christian Sire, Jean Bourhis
OBJECTIVE: To analyze the outcome of N3 patients treated with very accelerated radiotherapy (VART) or different schedules of concurrent chemoradiotherapy (CRT) within two phase III trials. PATIENTS AND METHODS: Data of 179 patients with N3 HNSCC from two GORTEC randomized trials (96-01 and 99-02) were pooled. Patients received either VART: 64.8Gy/3.5weeks or one of the 3 following CRT regimens: Conventional CRT: 70Gy/7weeks+3 cycles carboplatin-5FU; Moderately accelerated CRT: 70Gy/6weeks+2 cycles carboplatin-5FU; Strongly intensified CRT: 64Gy/5weeks+cisplatin (days 2, 16, 30) and 5 FU (days 1-5, 29-33) followed by 2 cycles adjuvant cisplatin-5FU...
August 2017: Oral Oncology
Gargi S Sarode, Sachin C Sarode, Shankargouda Patil
No abstract text is available yet for this article.
August 2017: Oral Oncology
Yosuke Kitani, Akira Kubota, Madoka Furukawa, Yukiko Hori, Yuko Nakayama, Tetsuo Nonaka, Nobutaka Mizoguchi, Yuka Kitani, Hiromitsu Hatakeyama, Nobuhiko Oridate
BACKGROUND: In patients with head and neck cancer, the management of second primary cancer (SPC) is particularly important for improving survival because of its high incidence and associated mortality. We evaluated the impact of combination chemotherapy on survival and SPC. METHOD: We retrospectively analyzed data from 49 patients treated with definitive radiation therapy (RT) for T2N0M0 laryngeal squamous cell carcinoma between 2003 and 2011. Among them, 22 patients received combined modality treatment with radiotherapy and S-1 (RT+CT group)...
August 2017: Oral Oncology
Leandro Luongo Matos, Rogerio Aparecido Dedivitis, Marco Aurélio Vamondes Kulcsar, Evandro Sobroza de Mello, Venâncio Avancini F Alves, Claudio Roberto Cernea
OBJECTIVES: To evaluate the new American Joint Committee on Cancer (AJCC) cancer staging manual (8th edition) in an independent cohort of patients surgically treated for oral squamous cell carcinoma in order to determine whether the upstaging of pT and pN classification was indicative of a worse prognosis. METHODS: A cohort of 298 patients was analyzed retrospectively. RESULTS: Of these patients, 22.8% received an upstaging when the depth of invasion was included into the pT classification...
August 2017: Oral Oncology
Virginia Osborn, Babak Givi, Anna Lee, Niki Sheth, Dylan Roden, David Schwartz, David Schreiber
OBJECTIVES: To analyze clinical, treatment and outcome data for patients with salivary ductal carcinoma in a large population-based sample. MATERIALS AND METHODS: The National Cancer Database was queried to identify patients diagnosed with salivary ductal carcinoma between 2004 and 2013. Kaplan Meier and Cox regression analysis were used to assess overall survival (OS) and identify impact of specific variables on OS. RESULTS: A total of 495 patients were identified...
August 2017: Oral Oncology
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