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Depression and Anxiety

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https://www.readbyqxmd.com/read/28636769/is-cannabis-treatment-for-anxiety-mood-and-related-disorders-ready-for-prime-time
#1
REVIEW
Jasmine Turna, Beth Patterson, Michael Van Ameringen
Anxiety and related disorders are the most common mental conditions affecting the North American population. Despite their established efficacy, first-line antidepressant treatments are associated with significant side effects, leading many afflicted individuals to seek alternative treatments. Cannabis is commonly viewed as a natural alternative for a variety of medical and mental health conditions. Currently, anxiety ranks among the top five medical symptoms for which North Americans report using medical marijuana...
June 21, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28632971/maternal-depression-and-bullying-victimization-among-adolescents-results-from-the-2004-pelotas-cohort-study
#2
Catarina Machado Azeredo, Iná S Santos, Aluísio J D Barros, Fernando C Barros, Alicia Matijasevich
BACKGROUND: Maternal depression impacts on several detrimental outcomes during a child's life course, and could increase their risk of victimization. This longitudinal study examined the association between antenatal maternal depression, postnatal trajectories, and current maternal depression and offspring bullying victimization at 11 years. METHODS: We included 3,441 11-year-old adolescents from the 2004 Pelotas Cohort Study. Antenatal maternal depression, postnatal trajectories, and current maternal depression data were assessed during the follow-up waves...
June 20, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28632961/increased-neural-response-to-social-rejection-in-major-depression
#3
Poornima Kumar, Gordon D Waiter, Magda Dubois, Maarten Milders, Ian Reid, J Douglas Steele
BACKGROUND: Being a part of community is critical for survival and individuals with major depressive disorder (MDD) have a greater sensitivity to interpersonal stress that makes them vulnerable to future episodes. Social rejection is a critical risk factor for depression and it is said to increase interpersonal stress and thereby impairing social functioning. It is therefore critical to understand the neural correlates of social rejection in MDD. METHODS: To this end, we scanned 15 medicated MDD and 17 healthy individuals during a modified cyberball passing game, where participants were exposed to increasing levels of social exclusion...
June 20, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28590587/genetic-variants-in-5-httlpr-bdnf-htr1a-comt-and-fkbp5-and-risk-for-treated-depression-after-cancer-diagnosis
#4
Nis P Suppli, Jens D Bukh, Terrie E Moffitt, Avshalom Caspi, Christoffer Johansen, Anne Tjønneland, Lars V Kessing, Susanne O Dalton
BACKGROUND: The role of gene-environment interactions in the pathogenesis of depression is unclear. Previous studies addressed vulnerability for depression after childhood adversity and stressful life events among carriers of numerous specific genetic variants; however, the importance of individual genetic variants, the environmental exposures with which they interact, and the magnitude of the risk conveyed by these interactions remain elusive. METHODS: We included 7,320 people with a first primary cancer identified in the prospective Diet, Cancer and Health study in an exposed-only cohort study...
June 7, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28569409/there-is-an-app-for-that-the-current-state-of-mobile-applications-apps-for-dsm-5-obsessive-compulsive-disorder-posttraumatic-stress-disorder-anxiety-and-mood-disorders
#5
REVIEW
Michael Van Ameringen, Jasmine Turna, Zahra Khalesi, Katrina Pullia, Beth Patterson
Mental health apps are viewed as a promising modality to extend the reach of mental health care beyond the clinic. They do so by providing a means of assessment, tracking, and treatment through a smartphone. Given that nearly 2/3 of the American population owns a smartphone, mental health apps offer the possibility of overcoming treatment barriers such as geographic location or financial barriers. Unfortunately, the excitement surrounding mental health apps may be premature as the current supporting literature regarding their efficacy is limited...
June 1, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28557299/internet-based-guided-self-help-for-posttraumatic-stress-disorder-ptsd-randomized-controlled-trial
#6
Catrin E Lewis, Daniel Farewell, Vicky Groves, Neil J Kitchiner, Neil P Roberts, Tracey Vick, Jonathan I Bisson
BACKGROUND: There are numerous barriers that limit access to evidence-based treatment for posttraumatic stress disorder (PTSD). Internet-based guided self-help is a treatment option that may help widen access to effective intervention, but the approach has not been sufficiently explored for the treatment of PTSD. METHODS: Forty two adults with DSM-5 PTSD of mild to moderate severity were randomly allocated to internet-based self-help with up to 3 h of therapist assistance, or to a delayed treatment control group...
May 29, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28556577/clinical-and-neurobiological-effects-of-aerobic-exercise-in-dental-phobia-a-randomized-controlled-trial
#7
Brigitt L Lindenberger, Jens Plag, Sarah Schumacher, Katharina Gaudlitz, Sophie Bischoff, Thomas Bobbert, Fernando Dimeo, Moritz B Petzold, Clemens Kirschbaum, Zsuzsa Dudás, Andreas Ströhle
BACKGROUND: Physical activity has shown to be effective in anxiety disorders. For specific phobia, no studies are available that systematically examined the effects of an aerobic exercise intervention on phobic fear within a randomized-controlled design. Therefore, we investigated the acute effect of a standardized aerobic training on clinical symptoms of dental phobia as well as on stress-related neurobiological markers. METHODS: Within a crossover design, 30 patients with dental phobia (mean age: 34...
May 26, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28543920/uncertainty-increases-neural-indices-of-attention-in-obsessive-compulsive-disorder
#8
Raoul Dieterich, Tanja Endrass, Norbert Kathmann
BACKGROUND: Patients with obsessive-compulsive disorder (OCD) experience abnormally high levels of uncertainty, and unpredictability is evaluated negatively and not well tolerated. The current study examined neural correlates of attentional processing in response to experimentally induced uncertainty in OCD. METHODS: Twenty-four OCD patients and 24 healthy controls performed a task where neutral and negative pictures were preceded by a cue, either being predictive (certain condition) or nonpredictive (uncertain condition) of subsequent picture valence...
May 25, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28543994/cognitive-enhancing-effects-of-rtms-administered-to-the-prefrontal-cortex-in-patients-with-depression-a-systematic-review-and-meta-analysis-of-individual-task-effects
#9
REVIEW
Donel M Martin, Shawn M McClintock, Jane J Forster, Tin Yan Lo, Colleen K Loo
BACKGROUND: Repetitive transcranial magnetic stimulation (rTMS) is an approved therapeutic treatment of major depressive disorder and has increasing clinical use throughout the world. However, it remains unclear whether an rTMS course for depression may also produce cognitive enhancement. In a recent meta-analysis of sham-controlled randomized controlled studies (RCTs) conducted in patients with neuropsychiatric conditions, no evidence was found for generalized cognitive enhancing effects across cognitive domains with active compared to sham rTMS...
May 24, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28544391/the-experience-sampling-method-as-an-mhealth-tool-to-support-self-monitoring-self-insight-and-personalized-health-care-in-clinical-practice
#10
Jim van Os, Simone Verhagen, Anne Marsman, Frenk Peeters, Maarten Bak, Machteld Marcelis, Marjan Drukker, Ulrich Reininghaus, Nele Jacobs, Tineke Lataster, Claudia Simons, Richel Lousberg, Sinan Gülöksüz, Carsten Leue, Peter C Groot, Wolfgang Viechtbauer, Philippe Delespaul
BACKGROUND: The experience sampling method (ESM) builds an intensive time series of experiences and contexts in the flow of daily life, typically consisting of around 70 reports, collected at 8-10 random time points per day over a period of up to 10 days. METHODS: With the advent of widespread smartphone use, ESM can be used in routine clinical practice. Multiple examples of ESM data collections across different patient groups and settings are shown and discussed, varying from an ESM evaluation of a 6-week randomized trial of mindfulness, to a twin study on emotion dynamics in daily life...
May 23, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28544045/are-there-sensitive-periods-when-child-maltreatment-substantially-elevates-suicide-risk-results-from-a-nationally-representative-sample-of-adolescents
#11
Stephanie H Gomez, Jenny Tse, Yan Wang, Brianna Turner, Alexander J Millner, Matthew K Nock, Erin C Dunn
BACKGROUND: Although child maltreatment is a well documented risk factor for suicidal behavior, little is known about whether the timing of child maltreatment differentially associates with risk of suicidal ideation, suicide plans, or suicide attempts. The goal of this study was to examine whether a first exposure to physical or sexual abuse during specific developmental periods significantly elevated risk for suicidal behavior in adolescents. METHODS: Data came from the National Comorbidity Survey Adolescent Supplement, a population-based sample of US adolescents aged 13-18 years old (n = 9,272)...
May 23, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28543958/latent-structure-of-negative-valence-measures-in-childhood
#12
Minyoung Lee, Steven H Aggen, Dever M Carney, Shannon Hahn, Elizabeth Moroney, Laura Machlin, Melissa A Brotman, Kenneth E Towbin, Ellen Leibenluft, Daniel S Pine, Roxann Roberson-Nay, John M Hettema
BACKGROUND: Internalizing disorders (IDs), consisting of the syndromes of anxiety and depression, are common, debilitating conditions often having onsets in adolescence. Scientists have developed dimensional self-report instruments that assess putative negative valence system (NVS) trait-like constructs as complimentary phenotypes to clinical symptoms. These include various measures that index temperamental predispositions to IDs and correlate with neural substrates of fear, anxiety, and affective regulation...
May 22, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28504861/the-efficacy-of-benzodiazepines-as-acute-anxiolytics-in-children-a-meta-analysis
#13
Heide Kuang, Jessica A Johnson, Jilian M Mulqueen, Michael H Bloch
OBJECTIVE: Current practice guidelines do not recommend benzodiazepines for acute management of anxiety disorders in pediatric patients. However, in procedural settings, benzodiazepines are commonly used to relieve acute preprocedural stress. This meta-analysis examines the efficacy and tolerability of benzodiazepines as short-term anxiolytics in children. METHOD: PubMed was searched for randomized controlled trials assessing the efficacy of benzodiazepines as short-term anxiolytics in pediatric patients...
May 15, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28504859/anxiety-there-is-an-app-for-that-a-systematic-review-of-anxiety-apps
#14
REVIEW
Madalina Sucala, Pim Cuijpers, Frederick Muench, Roxana Cardoș, Radu Soflau, Anca Dobrean, Patriciu Achimas-Cadariu, Daniel David
BACKGROUND: Smartphones and mobile devices have become ubiquitous, and with the rapid advance of technology, the number of health applications (apps) that are available for consumers on these devices is constantly growing. In particular, there has been a recent proliferation of anxiety apps. However, there has been no review of the quality or content of these anxiety apps and little is known about their purpose, the features they contain, and their empirical support. The goal of this systematic review was to assess the commercially available anxiety apps...
May 15, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28499066/perceiving-social-pressure-not-to-feel-negative-predicts-depressive-symptoms-in-daily-life
#15
Egon Dejonckheere, Brock Bastian, Eiko I Fried, Sean C Murphy, Peter Kuppens
BACKGROUND: Western societies often overemphasize the pursuit of happiness, and regard negative feelings such as sadness or anxiety as maladaptive and unwanted. Despite this emphasis on happiness, the amount of people suffering from depressive complaints is remarkably high. To explain this apparent paradox, we examined whether experiencing social pressure not to feel sad or anxious could in fact contribute to depressive symptoms. METHODS: A sample of individuals (n = 112) with elevated depression scores (Patient Health Questionnaire [PHQ-9] ≥ 10) took part in an online daily diary study in which they rated their depressive symptoms and perceived social pressure not to feel depressed or anxious for 30 consecutive days...
May 12, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28494123/ecological-momentary-interventions-for-depression-and-anxiety
#16
Stephen M Schueller, Adrian Aguilera, David C Mohr
Ecological momentary interventions (EMIs) are becoming more popular and more powerful resources for the treatment and prevention of depression and anxiety due to advances in technological capacity and analytic sophistication. Previous work has demonstrated that EMIs can be effective at reducing symptoms of depression and anxiety as well as related outcomes of stress and at increasing positive psychological functioning. In this review, we highlight the differences between EMIs and other forms of treatment due to the nature of EMIs to be deeply integrated into the fabric of people's day-to-day lives...
May 11, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28494120/posttraumatic-stress-disorder-symptom-severity-is-associated-with-reduced-default-mode-network-connectivity-in-individuals-with-elevated-genetic-risk-for-psychopathology
#17
Danielle R Miller, Mark W Logue, Erika J Wolf, Hannah Maniates, Meghan E Robinson, Jasmeet P Hayes, Annjanette Stone, Steven Schichman, Regina E McGlinchey, William P Milberg, Mark W Miller
BACKGROUND: Accumulating evidence suggests that posttraumatic stress disorder (PTSD) is associated with disrupted default mode network (DMN) connectivity, but findings across studies have not been uniform. Individual differences in relevant genes may account for some of the reported variability in the relationship between DMN connectivity and PTSD. In this study, we investigated this possibility using genome-wide association study (GWAS) derived polygenic risk scores (PRSs) for relevant psychiatric traits...
May 11, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28489327/new-directions-for-the-treatment-of-depression-targeting-the-photic-regulation-of-arousal-and-mood-pram-pathway
#18
REVIEW
Hannah E Bowrey, Morgan H James, Gary Aston-Jones
Both preclinical and clinical studies demonstrate that depression is strongly associated with reduced light availability, which in turn contributes to decreased function of brain regions that control mood. Here, we review findings that support a critical pathway for the control of mood that depends upon ambient light. We put forward a novel hypothesis, functionally linking retina to locus coeruleus (LC) in depression, and discuss the role of norepinephrine in affective disease. Finally, we discuss how utilizing the chemogenetic tool Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) to precisely control this retina-LC circuit may be used as a novel therapeutic to treat depression...
May 10, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28489321/nicotine-deprivation-attenuates-panic-reactivity-in-smokers-findings-from-a-placebo-controlled-nicotine-patch-study
#19
Kenneth Abrams, Sam Krimmel, Stacey Johnson, Kate Cieslowski, Helen Strnad, Arielle Melum, Caroline Kryder
BACKGROUND: Prospective studies consistently find that smoking is a risk factor for the development of panic disorder (PD). A possible explanation is that nicotine deprivation promotes heightened sensitivity to bodily sensations and/or arterial carbon dioxide (CO2 ). Abrams et al. (2011) previously found that, in response to a CO2 rebreathing challenge, smokers experiencing more (vs. less) intense nicotine withdrawal had more severe panic symptoms and a stronger urge to escape. However, participants were aware of the last time they smoked, leaving unclear the extent to which fear reactivity was influenced by the pharmacologic effects of nicotine deprivation versus beliefs regarding when nicotine was most recently used...
May 10, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28489319/low-physical-activity-as-a-key-differentiating-factor-in-the-potential-high-risk-profile-for-depressive-symptoms-in-older-adults
#20
Sofie Holmquist, Sabina Mattsson, Ingrid Schele, Peter Nordström, Anna Nordström
BACKGROUND: The identification of potential high-risk groups for depression is of importance. The purpose of the present study was to identify high-risk profiles for depressive symptoms in older individuals, with a focus on functional performance. METHODS: The population-based Healthy Ageing Initiative included 2,084 community-dwelling individuals (49% women) aged 70. Explorative cluster analysis was used to group participants according to functional performance level, using measures of basic mobility skills, gait variability, and grip strength...
May 10, 2017: Depression and Anxiety
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