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Depression and Anxiety

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https://www.readbyqxmd.com/read/29749006/predictors-of-recurrence-in-remitted-late-life-depression
#1
Yi Deng, Douglas R McQuoid, Guy G Potter, David C Steffens, Kimberly Albert, Meghan Riddle, John L Beyer, Warren D Taylor
BACKGROUND: Late-life depression (LLD) is associated with a fragile antidepressant response and high recurrence risk. This study examined what measures predict recurrence in remitted LLD. METHODS: Individuals of age 60 years or older with a Diagnostic and Statistical Manual - IV (DSM-IV) diagnosis of major depressive disorder were enrolled in the neurocognitive outcomes of depression in the elderly study. Participants received manualized antidepressant treatment and were followed longitudinally for an average of 5 years...
May 10, 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29748993/use-of-crisis-management-interventions-among-suicidal-patients-results-of-a-randomized-controlled-trial
#2
Craig J Bryan, Alexis M May, David C Rozek, Sean R Williams, Tracy A Clemans, Jim Mintz, Bruce Leeson, T Scott Burch
BACKGROUND: Previous research supports the efficacy of the crisis response plan (CRP) for the reduction of suicidal behaviors as compared to treatment as usual (TAU). Patient perspectives and use of the CRP, and their relationship to later suicidal thoughts, remain unknown. METHODS: A secondary analysis of a randomized clinical trial comparing a standard CRP (S-CRP), a CRP enhanced with reasons for living (E-CRP), and TAU in a sample of 97 active-duty U.S. Army personnel was conducted...
May 10, 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29745445/prevalence-of-psychiatric-morbidity-in-united-states-military-spouses-the-millennium-cohort-family-study
#3
Maria M Steenkamp, Nida H Corry, Meng Qian, Meng Li, Hope Seib McMaster, John A Fairbank, Valerie A Stander, Laura Hollahan, Charles R Marmar
BACKGROUND: Approximately half of US service members are married, equating to 1.1 million military spouses, yet the prevalence of psychiatric morbidity among military spouses remains understudied. We assessed the prevalence and correlates of eight mental health conditions in spouses of service members with 2-5 years of service. METHOD: We employed baseline data from the Millennium Cohort Family Study, a 21-year longitudinal survey following 9,872 military-affiliated married couples representing all US service branches and active duty, Reserve, and National Guard components...
May 10, 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29734494/error-related-brain-activity-in-adolescents-with-obsessive-compulsive-disorder-and-major-depressive-disorder
#4
Gregory L Hanna, Yanni Liu, Yona E Isaacs, Angela M Ayoub, Alice Brosius, Zachary Salander, Paul D Arnold, William J Gehring
BACKGROUND: The error-related negativity (ERN) is a negative deflection in the event-related potential following a mistake that is often increased in patients with obsessive-compulsive disorder (OCD). The relationship of the ERN to comorbid major depressive disorder (MDD) has not been examined in adolescents with OCD. This study compared ERN amplitudes in OCD patients with MDD (OCD + MDD), OCD patients without MDD (OCD - MDD), MDD patients, and healthy controls (HC). METHOD: The ERN, correct response negativity, and accuracy were measured during a flanker task to assess performance monitoring in 53 adolescents with a lifetime diagnosis of OCD, 36 adolescents with a lifetime diagnosis of MDD, and 89 age-matched HC of 13-18 years...
May 7, 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29734488/virtual-reality-exposure-versus-prolonged-exposure-for-ptsd-which-treatment-for-whom
#5
Aaron M Norr, Derek J Smolenski, Andrea C Katz, Albert A Rizzo, Barbara O Rothbaum, JoAnn Difede, Patricia Koenen-Woods, Mark A Reger, Greg M Reger
BACKGROUND: The majority of studies comparing active psychological treatments for posttraumatic stress disorder (PTSD) do not find significant differences at posttreatment. This was the case in a recent trial examining prolonged exposure (PE) and virtual reality exposure (VRE) among active-duty soldiers with combat-related PTSD. Matching individual patients to specific treatments provides a potential avenue to improve significantly the public health impact of effective treatments for PTSD...
May 7, 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29734487/cortical-thickness-and-white-matter-integrity-abnormalities-in-obsessive-compulsive-disorder-a-combined-multimodal-surface-based-morphometry-and-tract-based-spatial-statistics-study
#6
Cong Zhou, Jian Xu, Liangliang Ping, Fengrui Zhang, Wei Chen, Zonglin Shen, Linling Jiang, Xiufeng Xu, Yuqi Cheng
BACKGROUND: Cerebral morphological abnormalities may play a key role in pathogenesis of obsessive-compulsive disorder (OCD). However, few studies have used multimodal imaging strategies to investigate alterations of cortical morphometry and white matter (WM) integrity. This study aimed to evaluate cortical thickness, cortical and subcortical volume, and WM integrity characteristics in OCD patients comprehensively. METHODS: We acquired magnetic resonance imaging (MRI) scans from 52 OCD patients and 46 well-matched healthy controls (HCs)...
May 7, 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29734486/pharmacogenetic-testing-among-patients-with-mood-and-anxiety-disorders-is-associated-with-decreased-utilization-and-cost-a-propensity-score-matched-study
#7
Roy H Perlis, Rajesh Mehta, Alison M Edwards, Arun Tiwari, Guido W Imbens
BACKGROUND: Naturalistic and small randomized trials have suggested that pharmacogenetic testing may improve treatment outcomes in depression, but its cost-effectiveness is not known. There is growing enthusiasm for personalized medicine, relying on genetic variation as a contributor to heterogeneity of treatment effects. We sought to examine the relationship between a commercial pharmacogenetic test for psychotropic medications and 6-month cost of care and utilization in a large commercial health plan...
May 7, 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29719093/interpersonal-psychotherapy-for-mood-and-behavior-dysregulation-pilot-randomized-trial
#8
Leslie Miller, Stefanie A Hlastala, Laura Mufson, Ellen Leibenluft, Gayane Yenokyan, Mark Riddle
BACKGROUND: Youth with chronic irritability and excessive reactivity, diagnosed as disruptive mood dysregulation disorder (DMDD), have social impairment in multiple settings (i.e., peers, school, and home). This paper presents a pilot randomized trial assessing the feasibility, acceptability, and preliminary efficacy of interpersonal psychotherapy (IPT) for mood and behavior dysregulation (IPT-MBD), an adapted version of IPT for depressed adolescents. IPT-MBD focuses on decreasing outbursts and irritability and improving interpersonal interactions...
May 2, 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29719089/associations-between-therapists-occupational-burnout-and-their-patients-depression-and-anxiety-treatment-outcomes
#9
Jaime Delgadillo, David Saxon, Michael Barkham
BACKGROUND: Occupational burnout is common in mental health professionals, but its impact on patient outcomes is as yet uncertain. This study aimed to investigate associations between therapist-level burnout and patient-level treatment outcomes after psychological therapy. METHODS: We used multilevel modeling using depression (PHQ-9) and anxiety (GAD-7) outcomes data from 2,223 patients nested within 49 therapists. Therapists completed a survey including the Oldenburg Burnout Inventory (OLBI) and a job satisfaction scale (JDSS)...
May 2, 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29719088/depressive-and-anxious-symptoms-and-20-year-mortality-evidence-from-the-stirling-county-study
#10
Ian Colman, Mila Kingsbury, Ewa Sucha, Nicholas J Horton, Jane M Murphy, Stephen E Gilman
BACKGROUND: Depression and anxiety disorders are highly comorbid, and share significant symptom overlap. Whereas depression has been consistently associated with excess mortality, the association between anxiety and mortality is less clear. Our aim was to identify constellations of anxious and depressive symptoms and examine their associations with mortality. METHOD: This study considers respondents from the 1970 (n = 1203) and 1992 (n = 1402) cohorts of the Stirling County study...
May 2, 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29697888/insomnia-mediates-the-longitudinal-relationship-between-anxiety-and-depressive-symptoms-in-a-nationally-representative-sample-of-adolescents
#11
Y Irina Li, Lisa R Starr, Laura Wray-Lake
BACKGROUND: Anxiety and depression are commonly comorbid with each other, with anxiety often temporally preceding the development of depression. Although increasingly research has begun to investigate the role of sleep problems in depression, no study has examined insomnia as a mediator in the longitudinal relationship between anxiety and subsequent depression. METHODS: The current study utilizes data from Waves I, II, and IV of the National Longitudinal Study of Adolescent to Adult Health, a nationally representative prospective study conducted over a 14-year period (n = 20,745, 50...
April 26, 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29697887/an-appraisal-of-the-trustworthiness-of-practice-guidelines-for-depression-and-anxiety-in-children-and-youth
#12
REVIEW
Kathryn Bennett, Darren Courtney, Stephanie Duda, Joanna Henderson, Peter Szatmari
OBJECTIVE: Little is known about the trustworthiness of clinical practice guidelines (PGs) relevant to child and youth depression or anxiety. To address this gap, we used systematic review methods to identify all available relevant PGs, quality appraise them, and make recommendations regarding which PGs are trustworthy and should be used by clinicians. METHODS: Prespecified inclusion criteria identified eligible PGs. Two independent trained reviewers applied the Appraisal of Guidelines for Research and Evaluation (AGREE II) tool...
April 26, 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29697885/yoga-for-anxiety-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#13
REVIEW
Holger Cramer, Romy Lauche, Dennis Anheyer, Karen Pilkington, Michael de Manincor, Gustav Dobos, Lesley Ward
Yoga has become a popular approach to improve emotional health. The aim of this review was to systematically assess and meta-analyze the effectiveness and safety of yoga for anxiety. Medline/PubMed, Scopus, the Cochrane Library, PsycINFO, and IndMED were searched through October 2016 for randomized controlled trials (RCTs) of yoga for individuals with anxiety disorders or elevated levels of anxiety. The primary outcomes were anxiety and remission rates, and secondary outcomes were depression, quality of life, and safety...
April 26, 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29697881/the-dsm-5-nonsuicidal-self-injury-disorder-among-incoming-college-students-prevalence-and-associations-with-12-month-mental-disorders-and-suicidal-thoughts-and-behaviors
#14
Glenn Kiekens, Penelope Hasking, Laurence Claes, Philippe Mortier, Randy P Auerbach, Mark Boyes, Pim Cuijpers, Koen Demyttenaere, Jennifer G Green, Ronald C Kessler, Matthew K Nock, Ronny Bruffaerts
BACKGROUND: Approximately one in five college students report a history of nonsuicidal self-injury. However, it is unclear how many students meet criteria for the recently proposed DSM-5 nonsuicidal self-injury disorder (NSSI-D). In this study, we used full NSSI-D criteria to identify those students most in need of clinical care. METHODS: Using data from the Leuven College Surveys (n = 4,565), we examined the 12-month prevalence of DSM-5 NSSI-D in a large and representative sample of incoming college students...
April 26, 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29697880/associations-between-socioeconomic-status-and-psychological-therapy-outcomes-a-systematic-review-and-meta-analysis
#15
Megan Finegan, Nick Firth, Caroline Wojnarowski, Jaime Delgadillo
BACKGROUND: Socioeconomic deprivation is associated with higher prevalence of mental health problems; however, the influence of socioeconomic status (SES) on psychological therapy outcomes is as yet unclear. AIM: To review published evidence on the association between indicators of SES (income, education, employment, neighborhood deprivation, social position) and the outcomes of psychological interventions for depression and anxiety. METHODS: Systematic review and meta-analysis of outcomes research studies published in the last 10 years...
April 26, 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29697875/a-systematic-review-and-meta-analysis-of-deep-brain-stimulation-for-depression
#16
REVIEW
Steve Kisely, Amy Li, Nicola Warren, Dan Siskind
BACKGROUND: Deep brain stimulation is increasingly being used for treatment-resistant depression. Blinded, randomized controlled trials of active versus sham treatment have been limited to small numbers. METHOD: We performed a systematic review and meta-analysis on the effectiveness of deep brain stimulation (DBS) in depression. Cochrane Central Register of Controlled Trials, PubMed/Medline, Embase and PsycINFO, Chinese Biomedical Literature Service System, and China Knowledge Resource Integrated Database were searched for single- or double placebo-controlled, crossover, and parallel-group trials in which DBS was compared with sham treatment using validated scales...
April 26, 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29689597/the-predictive-value-of-approach-and-avoidance-tendencies-on-the-onset-and-course-of-depression-and-anxiety-disorders
#17
Sascha Y Struijs, Femke Lamers, Mike Rinck, Karin Roelofs, Philip Spinhoven, Brenda W J H Penninx
BACKGROUND: Trait and automatic approach-avoidance (AA) tendencies are central concepts in research on affective disorders. We longitudinally examined the associations of trait and automatic AA tendencies with the risk of onset and chronicity of anxiety and depressive disorders. METHODS: Participants were subdivided into those with (n = 766) versus without (n = 1,636) a current anxiety or depression diagnosis at baseline. Clinical diagnoses were reassessed after 2-year follow-up...
April 24, 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29667739/maternal-depressive-symptoms-during-and-after-pregnancy-and-child-developmental-milestones
#18
Soile Tuovinen, Marius Lahti-Pulkkinen, Polina Girchenko, Jari Lipsanen, Jari Lahti, Kati Heinonen, Rebecca M Reynolds, Esa Hämäläinen, Eero Kajantie, Hannele Laivuori, Anu-Katriina Pesonen, Pia M Villa, Katri Räikkönen
BACKGROUND: Maternal depressive symptoms during and after pregnancy predict poorer child neurodevelopment. The effects of timing, symptom severity, and additive influences remain unclear. METHODS: A total of 2,231 mothers of the Prediction and Prevention of Pre-eclampsia and Intrauterine Growth Restriction (PREDO) study completed the Center for Epidemiological Studies Depression Scale biweekly up to 14 times during pregnancy and twice up to 12 months after pregnancy...
April 18, 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29659141/risk-and-protective-factors-underlying-depression-and-suicidal-ideation-in-autism-spectrum-disorder
#19
Darren Hedley, Mirko Uljarević, Kitty-Rose Foley, Amanda Richdale, Julian Trollor
BACKGROUND: People with Autism Spectrum Disorder (ASD) are at significantly increased risk of suicidal thoughts and behavior. Given that social difficulties in ASD often lead to social isolation, which can in turn increase the risk for depression, this study examined loneliness and social support as potential risk and protective factors associated with depression and suicidal ideation. METHOD: The sample comprised 185 people (92 females) with ASD aged 14 to 80 years who were participating in a national survey...
April 16, 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29659120/patterns-of-depressive-symptom-remission-during-the-treatment-of-seasonal-affective-disorder-with-cognitive-behavioral-therapy-or-light-therapy
#20
Jonah Meyerhoff, Michael A Young, Kelly J Rohan
BACKGROUND: To elucidate mechanisms related to remission in winter seasonal affective disorder (SAD), we explored the course of individual depressive symptom offset across two distinct treatment modalities that show comparable outcomes at treatment endpoint: cognitive-behavioral therapy for SAD (CBT-SAD) and light therapy (LT). METHOD: One hundred seventy-seven adults with SAD in a depressive episode were randomized to 6-weeks of CBT-SAD (n = 88) or LT (n = 89)...
April 16, 2018: Depression and Anxiety
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