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Depression and Anxiety

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https://www.readbyqxmd.com/read/28715852/treatment-of-premenstrual-dysphoria-with-continuous-versus-intermittent-dosing-of-oral-contraceptives-results-of-a-three-arm-randomized-controlled-trial
#1
Tory A Eisenlohr-Moul, Susan S Girdler, Jacqueline L Johnson, Peter J Schmidt, David R Rubinow
BACKGROUND: Although traditionally dosed combined oral contraceptives (COCs) (21 days of active pills, 7 days of inactive pills) have not been demonstrated as superior to placebo for the treatment of premenstrual dysphoria (PMD), some randomized controlled trials (RCTs) indicate that oral contraceptives administered with a shortened or eliminated hormone-free interval are superior to placebo. However, results of such trials are mixed, and no existing studies have directly compared continuous and intermittent dosing schedules of the same oral contraceptive...
July 17, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28715850/how-willing-are-you-willingness-as-a-predictor-of-change-during-treatment-of-adults-with-obsessive-compulsive-disorder
#2
Adam M Reid, Lauryn E Garner, Nathaniel Van Kirk, Christina Gironda, Jason W Krompinger, Brian P Brennan, Brittany M Mathes, Sadie Cole Monaghan, Eric D Tifft, Marie-Christine André, Jordan Cattie, Jesse M Crosby, Jason A Elias
OBJECTIVE: Exposure and response prevention (ERP) is an effective treatment for individuals with obsessive-compulsive disorder (OCD), yet a substantial number of individuals with OCD do not fully respond to this intervention. Based on emerging experimental and clinical research on acceptance, this study sought to explore whether willingness to experience unpleasant thoughts, emotions, and bodily sensations during ERP was associated with improved treatment response. METHODS: Two hundred eighty-eight adults with OCD receiving residential ERP provided self-rated willingness and other exposure-related variables during each daily coached ERP session...
July 17, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28672073/prediction-of-treatment-outcomes-to-exercise-in-patients-with-nonremitted-major-depressive-disorder
#3
Chad D Rethorst, Charles C South, A John Rush, Tracy L Greer, Madhukar H Trivedi
BACKGROUND: Only one-third of patients with major depressive disorder (MDD) achieve remission with initial treatment. Consequently, current clinical practice relies on a "trial-and-error" approach to identify an effective treatment for each patient. The purpose of this report was to determine whether we could identify a set of clinical and biological parameters with potential clinical utility for prescription of exercise for treatment of MDD in a secondary analysis of the Treatment with Exercise Augmentation in Depression (TREAD) trial...
July 3, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28661072/sensing-behavioral-symptoms-of-mental-health-and-delivering-personalized-interventions-using-mobile-technologies
#4
REVIEW
Min Hane Aung, Mark Matthews, Tanzeem Choudhury
Unlike most other health conditions, the treatment of mental illness relies on subjective measurement. In addition, the criteria for diagnosing mental illnesses are based on broad categories of symptoms that do not account for individual deviations from these criteria. The increasing availability of personal digital devices, such as smartphones that are equipped with sensors, offers a new opportunity to continuously and passively measure human behavior in situ. This promises to lead to more precise assessment of human behavior and ultimately individual mental health...
June 29, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28661053/examining-the-scope-and-patterns-of-deliberate-self-injurious-cutting-content-in-popular-social-media
#5
Elizabeth M Miguel, Tommy Chou, Alejandra Golik, Danielle Cornacchio, Amanda L Sanchez, Mariah DeSerisy, Jonathan S Comer
BACKGROUND: Social networking services (SNS) have rapidly become a central platform for adolescents' social interactions and media consumption patterns. The present study examined a representative sample of publicly accessible content related to deliberate self-injurious cutting across three SNS platforms: Twitter, Tumblr, and Instagram. METHODS: Data collection simulated searches for publicly available deliberate self-injury content on Twitter, Tumblr, and Instagram...
June 29, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28661022/transdiagnostic-emotional-vulnerabilities-linking-obsessive-compulsive-and-depressive-symptoms-in-a-community-based-sample-of-adolescents
#6
Gregory S Chasson, Mariel S Bello, Alexandria M Luxon, Trevor A A Graham, Adam M Leventhal
BACKGROUND: Transdiagnostic emotional vulnerabilities are suspected to underlie psychopathologic comorbidity but have received little attention in adolescent emotional pathology literature. We examined distress tolerance, anxiety sensitivity, and anhedonia as concomitant transdiagnostic mechanisms that account for (i.e., statistically mediate) the covariance between adolescent obsessive-compulsive disorder (OCD) and major depressive disorder (MDD) symptoms. METHOD: Data on MDD, OCD, and the three aforementioned transdiagnostic vulnerabilities were collected from a community-based sample of 3,094 ninth graders in a large metropolitan area and analyzed using mixed effects modeling to evaluate mediation effects...
June 29, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28640965/atypical-depression-and-double-depression-predict-new-onset-cardiovascular-disease-in-u-s-adults
#7
Stephanie M Case, Manisha Sawhney, Jesse C Stewart
BACKGROUND: Although depression is a risk factor for cardiovascular disease (CVD), it is unknown whether this risk varies across depressive disorder subtypes. Thus, we investigated atypical major depressive disorder (MDD) and double depression as predictors of new-onset CVD in a nationally representative sample of U.S. adults. METHODS: Prospective data from 28,726 adults initially free of CVD who participated in Wave 1 (2001-2002) and Wave 2 (2004-2005) of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) were examined...
June 22, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28636769/is-cannabis-treatment-for-anxiety-mood-and-related-disorders-ready-for-prime-time
#8
REVIEW
Jasmine Turna, Beth Patterson, Michael Van Ameringen
Anxiety and related disorders are the most common mental conditions affecting the North American population. Despite their established efficacy, first-line antidepressant treatments are associated with significant side effects, leading many afflicted individuals to seek alternative treatments. Cannabis is commonly viewed as a natural alternative for a variety of medical and mental health conditions. Currently, anxiety ranks among the top five medical symptoms for which North Americans report using medical marijuana...
June 21, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28632971/maternal-depression-and-bullying-victimization-among-adolescents-results-from-the-2004-pelotas-cohort-study
#9
Catarina Machado Azeredo, Iná S Santos, Aluísio J D Barros, Fernando C Barros, Alicia Matijasevich
BACKGROUND: Maternal depression impacts on several detrimental outcomes during a child's life course, and could increase their risk of victimization. This longitudinal study examined the association between antenatal maternal depression, postnatal trajectories, and current maternal depression and offspring bullying victimization at 11 years. METHODS: We included 3,441 11-year-old adolescents from the 2004 Pelotas Cohort Study. Antenatal maternal depression, postnatal trajectories, and current maternal depression data were assessed during the follow-up waves...
June 20, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28632961/increased-neural-response-to-social-rejection-in-major-depression
#10
Poornima Kumar, Gordon D Waiter, Magda Dubois, Maarten Milders, Ian Reid, J Douglas Steele
BACKGROUND: Being a part of community is critical for survival and individuals with major depressive disorder (MDD) have a greater sensitivity to interpersonal stress that makes them vulnerable to future episodes. Social rejection is a critical risk factor for depression and it is said to increase interpersonal stress and thereby impairing social functioning. It is therefore critical to understand the neural correlates of social rejection in MDD. METHODS: To this end, we scanned 15 medicated MDD and 17 healthy individuals during a modified cyberball passing game, where participants were exposed to increasing levels of social exclusion...
June 20, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28590587/genetic-variants-in-5-httlpr-bdnf-htr1a-comt-and-fkbp5-and-risk-for-treated-depression-after-cancer-diagnosis
#11
Nis P Suppli, Jens D Bukh, Terrie E Moffitt, Avshalom Caspi, Christoffer Johansen, Anne Tjønneland, Lars V Kessing, Susanne O Dalton
BACKGROUND: The role of gene-environment interactions in the pathogenesis of depression is unclear. Previous studies addressed vulnerability for depression after childhood adversity and stressful life events among carriers of numerous specific genetic variants; however, the importance of individual genetic variants, the environmental exposures with which they interact, and the magnitude of the risk conveyed by these interactions remain elusive. METHODS: We included 7,320 people with a first primary cancer identified in the prospective Diet, Cancer and Health study in an exposed-only cohort study...
June 7, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28569409/there-is-an-app-for-that-the-current-state-of-mobile-applications-apps-for-dsm-5-obsessive-compulsive-disorder-posttraumatic-stress-disorder-anxiety-and-mood-disorders
#12
REVIEW
Michael Van Ameringen, Jasmine Turna, Zahra Khalesi, Katrina Pullia, Beth Patterson
Mental health apps are viewed as a promising modality to extend the reach of mental health care beyond the clinic. They do so by providing a means of assessment, tracking, and treatment through a smartphone. Given that nearly 2/3 of the American population owns a smartphone, mental health apps offer the possibility of overcoming treatment barriers such as geographic location or financial barriers. Unfortunately, the excitement surrounding mental health apps may be premature as the current supporting literature regarding their efficacy is limited...
June 1, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28557299/internet-based-guided-self-help-for-posttraumatic-stress-disorder-ptsd-randomized-controlled-trial
#13
Catrin E Lewis, Daniel Farewell, Vicky Groves, Neil J Kitchiner, Neil P Roberts, Tracey Vick, Jonathan I Bisson
BACKGROUND: There are numerous barriers that limit access to evidence-based treatment for posttraumatic stress disorder (PTSD). Internet-based guided self-help is a treatment option that may help widen access to effective intervention, but the approach has not been sufficiently explored for the treatment of PTSD. METHODS: Forty two adults with DSM-5 PTSD of mild to moderate severity were randomly allocated to internet-based self-help with up to 3 h of therapist assistance, or to a delayed treatment control group...
May 29, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28556577/clinical-and-neurobiological-effects-of-aerobic-exercise-in-dental-phobia-a-randomized-controlled-trial
#14
Brigitt L Lindenberger, Jens Plag, Sarah Schumacher, Katharina Gaudlitz, Sophie Bischoff, Thomas Bobbert, Fernando Dimeo, Moritz B Petzold, Clemens Kirschbaum, Zsuzsa Dudás, Andreas Ströhle
BACKGROUND: Physical activity has shown to be effective in anxiety disorders. For specific phobia, no studies are available that systematically examined the effects of an aerobic exercise intervention on phobic fear within a randomized-controlled design. Therefore, we investigated the acute effect of a standardized aerobic training on clinical symptoms of dental phobia as well as on stress-related neurobiological markers. METHODS: Within a crossover design, 30 patients with dental phobia (mean age: 34...
May 26, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28543920/uncertainty-increases-neural-indices-of-attention-in-obsessive-compulsive-disorder
#15
Raoul Dieterich, Tanja Endrass, Norbert Kathmann
BACKGROUND: Patients with obsessive-compulsive disorder (OCD) experience abnormally high levels of uncertainty, and unpredictability is evaluated negatively and not well tolerated. The current study examined neural correlates of attentional processing in response to experimentally induced uncertainty in OCD. METHODS: Twenty-four OCD patients and 24 healthy controls performed a task where neutral and negative pictures were preceded by a cue, either being predictive (certain condition) or nonpredictive (uncertain condition) of subsequent picture valence...
May 25, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28543994/cognitive-enhancing-effects-of-rtms-administered-to-the-prefrontal-cortex-in-patients-with-depression-a-systematic-review-and-meta-analysis-of-individual-task-effects
#16
REVIEW
Donel M Martin, Shawn M McClintock, Jane J Forster, Tin Yan Lo, Colleen K Loo
BACKGROUND: Repetitive transcranial magnetic stimulation (rTMS) is an approved therapeutic treatment of major depressive disorder and has increasing clinical use throughout the world. However, it remains unclear whether an rTMS course for depression may also produce cognitive enhancement. In a recent meta-analysis of sham-controlled randomized controlled studies (RCTs) conducted in patients with neuropsychiatric conditions, no evidence was found for generalized cognitive enhancing effects across cognitive domains with active compared to sham rTMS...
May 24, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28544391/the-experience-sampling-method-as-an-mhealth-tool-to-support-self-monitoring-self-insight-and-personalized-health-care-in-clinical-practice
#17
Jim van Os, Simone Verhagen, Anne Marsman, Frenk Peeters, Maarten Bak, Machteld Marcelis, Marjan Drukker, Ulrich Reininghaus, Nele Jacobs, Tineke Lataster, Claudia Simons, Richel Lousberg, Sinan Gülöksüz, Carsten Leue, Peter C Groot, Wolfgang Viechtbauer, Philippe Delespaul
BACKGROUND: The experience sampling method (ESM) builds an intensive time series of experiences and contexts in the flow of daily life, typically consisting of around 70 reports, collected at 8-10 random time points per day over a period of up to 10 days. METHODS: With the advent of widespread smartphone use, ESM can be used in routine clinical practice. Multiple examples of ESM data collections across different patient groups and settings are shown and discussed, varying from an ESM evaluation of a 6-week randomized trial of mindfulness, to a twin study on emotion dynamics in daily life...
May 23, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28544045/are-there-sensitive-periods-when-child-maltreatment-substantially-elevates-suicide-risk-results-from-a-nationally-representative-sample-of-adolescents
#18
Stephanie H Gomez, Jenny Tse, Yan Wang, Brianna Turner, Alexander J Millner, Matthew K Nock, Erin C Dunn
BACKGROUND: Although child maltreatment is a well documented risk factor for suicidal behavior, little is known about whether the timing of child maltreatment differentially associates with risk of suicidal ideation, suicide plans, or suicide attempts. The goal of this study was to examine whether a first exposure to physical or sexual abuse during specific developmental periods significantly elevated risk for suicidal behavior in adolescents. METHODS: Data came from the National Comorbidity Survey Adolescent Supplement, a population-based sample of US adolescents aged 13-18 years old (n = 9,272)...
May 23, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28543958/latent-structure-of-negative-valence-measures-in-childhood
#19
Minyoung Lee, Steven H Aggen, Dever M Carney, Shannon Hahn, Elizabeth Moroney, Laura Machlin, Melissa A Brotman, Kenneth E Towbin, Ellen Leibenluft, Daniel S Pine, Roxann Roberson-Nay, John M Hettema
BACKGROUND: Internalizing disorders (IDs), consisting of the syndromes of anxiety and depression, are common, debilitating conditions often having onsets in adolescence. Scientists have developed dimensional self-report instruments that assess putative negative valence system (NVS) trait-like constructs as complimentary phenotypes to clinical symptoms. These include various measures that index temperamental predispositions to IDs and correlate with neural substrates of fear, anxiety, and affective regulation...
May 22, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28504861/the-efficacy-of-benzodiazepines-as-acute-anxiolytics-in-children-a-meta-analysis
#20
Heide Kuang, Jessica A Johnson, Jilian M Mulqueen, Michael H Bloch
OBJECTIVE: Current practice guidelines do not recommend benzodiazepines for acute management of anxiety disorders in pediatric patients. However, in procedural settings, benzodiazepines are commonly used to relieve acute preprocedural stress. This meta-analysis examines the efficacy and tolerability of benzodiazepines as short-term anxiolytics in children. METHOD: PubMed was searched for randomized controlled trials assessing the efficacy of benzodiazepines as short-term anxiolytics in pediatric patients...
May 15, 2017: Depression and Anxiety
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