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Parasitology International

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https://www.readbyqxmd.com/read/28527785/the-effectiveness-of-a-fixed-dose-combination-pour-on-formulation-of-1-25-fipronil-and-2-5-fluazuron-against-economically-important-ectoparasites-and-associated-pharmacokinetics-in-cattle
#1
Welber Daniel Zanetti Lopes, Rafael Marin Chiummo, Luis Fernando Vettorato, Daniel de Castro Rodrigues, Rafael Bazaglia Sonada
The present work consisted of eight studies to evaluate the ectoparasiticidal spectrum and determine the pharmacokinetic parameters of a pour-on combination of fipronil 1.25mg/kg+fluazuron 2.5mg/kg for cattle against Rhipicephalus microplus, Haematobia irritans and the larvae of Dermatobia hominis and Cochliomyia hominivorax. The analysis fipronil and fluazuron were performed by liquid chromatography using a mass detector for the detection and quantification of analytes (LC-MS/MS). Additionally, in two of these studies, the animals were artificially infested with R...
May 17, 2017: Parasitology International
https://www.readbyqxmd.com/read/28526420/responses-to-comments-in-a-letter-to-the-editor-parint_2017_67-anonymized
#2
EDITORIAL
Yasushi Kawakami
No abstract text is available yet for this article.
May 16, 2017: Parasitology International
https://www.readbyqxmd.com/read/28501634/helminth-infracommunity-of-the-cane-toad-rhinella-marina-anura-bufonidae-within-its-native-distribution-range
#3
Nallely Ruiz-Torres, Luis García-Prieto, Omar Lagunas-Calvo, Juan Violante-González, David Osorio Sarabia
During August 2010, a total of 66 cane toad Rhinella marina were collected in Laguna de Coyuca, Guerrero, Mexico and examined for the presence of helminths. Ninety-two percent were parasitized by 1 or more parasite species. A total of 4624 individuals were found, belonging to 8 helminth taxa (1 digenean, 1 cestode and 6 nematodes). Infracommunities harbored by this host species are highly variable (mean Jaccard similarity index 0.31±0.27); mean percent similarity index 0.26±0.32) and depauperate (mean richness 1...
May 10, 2017: Parasitology International
https://www.readbyqxmd.com/read/28499980/morphological-and-molecular-identification-of-sarcocystis-arctica-sarcocysts-in-three-red-foxes-vulpes-vulpes-from-the-czech-republic
#4
Ivan Pavlásek, Ondřej Máca
Muscular sarcocystosis by Sarcocystis arctica was found for the first time in the Czech Republic, in different muscles of red fox (Vulpes vulpes). Cysts were slim, elongated, thread-like, whitish, 1-7mm long, and 206-270μm wide; bradyzoites were 7.9×2.7μm in unstained wet mounts and 9.2×2.9μm in cyst Giemsa-stained smears. The cyst wall was thin, with short villi-like protrusions, and no host response was observed in the histological sections. Examination of the distribution and intensity of sarcocysts in 17 different muscle groups revealed that the highest intensity was in the cranial tibial muscle (>15 cysts in compressoria), followed by the diaphragm, forearm, and other groups (with intensities of 3-15 cysts in compressoria)...
May 9, 2017: Parasitology International
https://www.readbyqxmd.com/read/28495225/detection-and-molecular-status-of-isospora-sp-from-the-domestic-pigeon-columba-livia-domestica
#5
Ryuma Matsubara, Yasuhiro Fukuda, Fumi Murakoshi, Osamu Nomura, Toru Suzuki, Chika Tada, Yutaka Nakai
The domestic pigeon, Columba livia domestica, is reared for meat production, as a pet, or for racing. Few reports have characterized the parasitic protists from the genus Isospora isolated from Columbiformes. We detected Isospora-like oocysts from C. livia reared for racing. The oocyst contained two sporocysts, and each sporocyst included four sporozoites. The sporulated oocysts (n=4) were spherical; their mean diameters were 25.6 (24.0-27.2)×24.7 (23.4-26.0) μm. Micropyles, polar granules, and oocyst residuum were absent...
May 8, 2017: Parasitology International
https://www.readbyqxmd.com/read/28483708/gamasoidosis-by-the-special-lineage-l1-of-dermanyssus-gallinae-acarina-dermanyssidae-a-case-of-heavy-infestation-in-a-public-place-in-italy
#6
Marco Pezzi, Marilena Leis, Milvia Chicca, Lise Roy
Among Gamasina (Acari: Mesostigmata) mites, some dermanyssoid species are known to cause gamasoidosis, a human dermatitis characterized by papulosquamous eruptions and urticarian lesions. We describe a case of mite infestation which occurred in public conference halls in Ferrara (Italy), affecting four people who attended the place and showed signs of gamasoidosis. The mites were collected and characterized using scanning electron microscopy, light microscopy and mitochondrial DNA sequencing (Cytochrome c oxidase subunit I partial CDS)...
May 5, 2017: Parasitology International
https://www.readbyqxmd.com/read/28476340/first-report-of-human-intestinal-sarcocystosis-in-cambodia
#7
Virak Khieu, Hanspeter Marti, Saomony Chhay, Meng Chuor Char, Sinuon Muth, Peter Odermatt
Human intestinal sarcocystosis (HIS), caused by Sarcocystis species, is acquired by eating undercooked meat from sarcocyst-containing cattle (S. hominis, S. heydorni) and pigs (S. suihominis). We report on the detection of human intestinal Sarcocystis infections in a cross-sectional survey of Strongyloides stercoralis in early 2014, in Rovieng District, Preah Vihear Province, northern Cambodia. Among 1081 participants, 108 (10.0%) were diagnosed with Sarcocystis spp. oocysts in stool samples. Males had a significantly higher risk of infection than females (OR: 1...
May 2, 2017: Parasitology International
https://www.readbyqxmd.com/read/28465107/seroprevalence-of-toxoplasma-gondii-in-humans-and-pigs-in-north-sulawesi-indonesia
#8
Josef Tuda, Sri Adiani, Madoka Ichikawa-Seki, Kousuke Umeda, Yoshifumi Nishikawa
Toxoplasma gondii, an intracellular protozoan parasite, is a major public health concern throughout the world. Importantly, toxoplasmosis has several adverse effects, including neurological and ocular diseases. There are currently no data on the prevalence of T. gondii infection in humans or animals in North Sulawesi, although Indonesia is known to have a high seroprevalence of this parasite. In this study, the prevalence of T. gondii was determined in samples of humans and pigs from North Sulawesi using the latex agglutination test...
April 29, 2017: Parasitology International
https://www.readbyqxmd.com/read/28456494/phosphoinositide-binding-profiles-of-the-px-domains-of-giardia-lamblia
#9
Ananya Jana, Abhishek Sinha, Srimonti Sarkar
The membrane trafficking machinery that functions at the endomembrane system of Giardia lamblia appears to be significantly different from that present in most model eukaryotes. This machinery is important for encystation as cyst wall material is trafficked to the cell surface via encystation-specific vesicles. Since proteins containing the phosphoinositide-binding PX domains are known regulators of vesicular trafficking, BLAST search was used to identify the PX domains of G. lamblia. Six putative PX domain-containing ORFs were identified...
April 26, 2017: Parasitology International
https://www.readbyqxmd.com/read/28449979/morphological-molecular-and-phylogenetic-analyses-of-diplotriaena-bargusinica-skrjabin-1917-nematoda-diplotriaenidae
#10
Thainá Dutra Vieira, Marcia Raquel Pegoraro de Macedo, Fabiana Fedatto Bernardon, Gertrud Müller
The nematode Diplotriaena bargusinica is a bird air sac parasite, and its taxonomy is based mainly on morphological and morphometric characteristics. Increasing knowledge of genetic information variability has spurred the use of DNA markers in conjunction with morphological data for inferring phylogenetic relationships in different taxa. Considering the potential of molecular biology in taxonomy, this study presents the morphological and molecular characterization of D. bargusinica, and establishes the phylogenetic position of the nematode in Spirurina...
April 24, 2017: Parasitology International
https://www.readbyqxmd.com/read/28445773/taxonomic-comments-on-diphyllobothrium-hottai-yazaki-fukumoto-abe-1988-cestoda-diphyllobothriidae
#11
EDITORIAL
Minoru Nakao, Tetsuya Yanagida
No abstract text is available yet for this article.
April 23, 2017: Parasitology International
https://www.readbyqxmd.com/read/28435029/activity-of-carboxylesterases-glutathione-s-transferase-and-monooxygenase-on-rhipicephalus-microplus-exposed-to-fluazuron
#12
Fabrício Nascimento Gaudêncio, Guilherme Marcondes Klafke, Vinícius Menezes Tunholi-Alves, Thaís Paes Ferreira, Cristiane Nunes Coelho, Adivaldo Henrique da Fonseca, Isabele da Costa Angelo, Jairo Pinheiro
The objective of this study was to assess the effect of the exposure to fluazuron on the activity of common pesticide detoxification enzyme groups in the cattle tick (Rhipicephalus microplus). Engorged females of a susceptible strain (POA) and a resistant strain (Jaguar) were exposed in vitro to fluazuron and their eggs and larvae were used to compare the activities of the general esterases, mixed-function oxidases (MFO) and glutathione-S-transferase (GST). The results showed significant elevation in MFO contents and esterases activity in the resistant strain when compared with the susceptible strain, in eggs and larvae respectively...
April 20, 2017: Parasitology International
https://www.readbyqxmd.com/read/28408356/possible-antifibrotic-effect-of-gdc-0449-vismodegib-a-hedgehog-pathway-inhibitor-in-mice-model-of-schistosoma-induced-liver-fibrosis
#13
Abeer A Elhenawy, Rehab H Ashour, Nairmen Nabih, Naglaa M Shalaby, Nirmeen Megahed
Liver fibrosis is a pathological process complicating schistosomiasis. It is an active process of continuous extracellular matrix accumulation. In Egypt, schistosomiasis re-infection is a continuing problem especially in rural areas. In this study we examined the antifibrotic effect of GDC-0449 (Vismodegib), a hedgehog-pathway inhibitor as a new molecular target for Schistosoma-induced liver fibrosis, in addition to exploring its effect as antischistosomal drug. The effect of GDC-0449 alone or combined with Praziquantel was tried experimentally in infected mice with Schistosoma mansoni...
April 10, 2017: Parasitology International
https://www.readbyqxmd.com/read/28396295/molecular-characterization-of-fasciola-flukes-obtained-from-wild-sika-deer-and-domestic-cattle-in-hokkaido-japan
#14
Madoka Ichikawa-Seki, Tomoko Shiroma, Tatsuya Kariya, Ryo Nakao, Yuma Ohari, Kei Hayashi, Shinya Fukumoto
The number of wild sika deer (Cervus nippon yesoensis) continues to increase in Hokkaido Prefecture, Japan. The major concern for the livestock industry is the transmission of pathogens between sika deer and cattle. Fasciolosis is an important disease that can occur in both animals. The aim of this study was to examine the possible mutual transmission of this disease in Hokkaido Prefecture. A total of 105 Fasciola flukes were obtained from sika deer and 96 from domestic cattle. The Fasciola flukes in Japan are reported to possess no mature sperm...
April 7, 2017: Parasitology International
https://www.readbyqxmd.com/read/28389349/bifunctional-activity-of-fused-plasmodium-falciparum-orotate-phosphoribosyltransferase-and-orotidine-5-monophosphate-decarboxylase
#15
Patsarawadee Paojinda, Waranya Imprasittichai, Sudaratana R Krungkrai, Nirianne Marie Q Palacpac, Toshihiro Horii, Jerapan Krungkrai
Fusion of the last two enzymes in the pyrimidine biosynthetic pathway in the inversed order by having a COOH-terminal orotate phosphoribosyltransferase (OPRT) and an NH2-terminal orotidine 5'-monophosphate decarboxylase (OMPDC), as OMPDC-OPRT, are described in many organisms. Here, we produced gene fusions of Plasmodium falciparum OMPDC-OPRT and expressed the bifunctional protein in Escherichia coli. The enzyme was purified to homogeneity using affinity and anion-exchange chromatography, exhibited enzymatic activities and functioned as a dimer...
April 4, 2017: Parasitology International
https://www.readbyqxmd.com/read/28385590/characterization-and-expression-pattern-of-a-novel-frizzled-8-receptor-gene-in-schistosoma-japonicum
#16
Jingxiu Xu, Xingang Feng, Yingying Jia, Yang Hong, Hao Li, Ke Lu, Jiaojiao Lin, Chunxiu Yuan, Mingxin Song
Wnt signaling as mediated by the Frizzled family receptors plays a vital role in the early development of animal embryos, organ formation, tissue regeneration and other physiological processes. In the present study, a novel Frizzled member, SjFz8, was isolated and characterized in Schistosoma japonicum. SjFz8 encodes an 1162-amino-acid protein with typical characteristics of Frizzled proteins. Quantitative real-time polymerase chain reaction analysis indicated that SjFz8 transcript level was highest in 7-day-old schistosomula...
April 3, 2017: Parasitology International
https://www.readbyqxmd.com/read/28385589/lymphocyte-responses-of-rats-vaccinated-with-cdna-encoding-a-phosphoglycerate-kinase-of-fasciola-hepatica-fhpgk-and-f-hepatica-infection
#17
Agnieszka Wesołowska, Anna Zawistowska-Deniziak, Luke J Norbury, Przemysław Wilkowski, Anna M Pyziel, Wojciech Zygner, Halina Wędrychowicz
Lymphocyte responses in the blood, peritoneal fluid and both mesenteric and hepatic lymph nodes of cDNA-FhPGK/pCMV vaccinated and/or Fasciola hepatica infected rats of both sexes were investigated to provide an insight into the immune responses that develop in different body compartments. The immune response that developed in cDNA-FhPGK/pCMV vaccinated females contributed to partial protection against F. hepatica infection (54% reduction in fluke recovery), while more liver flukes were found in the livers and bile ducts of cDNA-FhPGK/pCMV vaccinated male rats than in unvaccinated animals (increase of 13%)...
April 3, 2017: Parasitology International
https://www.readbyqxmd.com/read/28377050/deciphering-the-effects-of-nelfinavir-and-lopinavir-on-epimastigote-forms-of-trypanosoma-cruzi
#18
Leandro Stefano Sangenito, Arthur A de Guedes, Diego S Gonçalves, Sergio H Seabra, Claudia M d'Avila-Levy, André L S Santos, Marta H Branquinha
No abstract text is available yet for this article.
April 1, 2017: Parasitology International
https://www.readbyqxmd.com/read/28366788/identification-and-characterization-of-guanosine-5-monophosphate-reductase-of-trypanosoma-congolense-as-a-drug-target
#19
Albertus Eka Yudistira Sarwono, Keisuke Suganuma, Shinya Mitsuhashi, Tadashi Okada, Simon Peter Musinguzi, Kengo Shigetomi, Noboru Inoue, Makoto Ubukata
Trypanosoma congolense is one of the most prevalent pathogens which causes trypanosomosis in African animals, resulting in a significant economic loss. In its life cycle, T. congolense is incapable of synthesizing purine nucleotides via a de novo pathway, and thus relies on a salvage pathway to survive. In this study, we identified a gene from T. congolense, TcIL3000_5_1940, as a guanosine 5'-monophosphate reductase (GMPR), an enzyme that modulates the concentration of intracellular guanosine in the pathogen...
March 30, 2017: Parasitology International
https://www.readbyqxmd.com/read/28359900/phylogenetic-position-of-the-genus-gonocerca-manter-1925-trematoda-hemiuroidea-based-on-partial-sequences-of-28s-rrna-gene-and-a-reconsideration-of-taxonomic-status-of-gonocercinae-skrjabin-et-guschanskaja-1955
#20
Sergey G Sokolov, Dmitry M Atopkin, Ilya I Gordeev, Marina B Shedko
Adult trematodes of the genus Gonocerca Manter, 1925, are parasites of marine fishes. Identification of the phylogenetic positions and a revision of the taxonomic status of the subfamily Gonocercinae Skrjabin et Guschanskaja, 1955 (Derogenidae) are the main purposes of this research article. Four Gonocerca species were used in the study, including the type-species G. phycidis Manter, 1925. Molecular phylogenetic analysis, based on partial sequences of 28S rRNA gene, revealed that Gonocerca spp. are phylogenetically distant from other hemiuroid trematodes, including Derogenes varicus (Müller, 1784), representative of the type-genus of the family Derogenidae...
March 27, 2017: Parasitology International
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