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Scandinavian Cardiovascular Journal: SCJ

Knut Gjesdal
No abstract text is available yet for this article.
October 13, 2016: Scandinavian Cardiovascular Journal: SCJ
Sten Lyager Nielsen
Transcatheter mitral valve (MV) intervention has emerged as an effective treatment option for symptomatic severe mitral regurgitation (MR) in patients considered to be inoperable or at high operative risk for surgical MV surgery. In primary mitral regurgitation, surgical repair is the standard of care. Transcatheter edge-to-edge MV repair with the MitraClip system has the largest clinical experience to date, and offers a sustained clinical benefit in selected surgical high-risk patients. Surgery for secondary MR remains a challenge...
October 13, 2016: Scandinavian Cardiovascular Journal: SCJ
Jonathan Engborg, Casper Riechel-Sarup, Oke Gerke, Hans Mickley, Niels Christian Sandgaard, Henrik Nissen, Axel Cosmus Pyndt Diederichsen
OBJECTIVES: Transcatheter aortic valve implantation (TAVI) is an established treatment for high-grade aortic valve stenosis in patients found unfit for open heart surgery. The method may cause cardiac conduction disorders requiring permanent pacemaker (PPM) implantation, and the long-term effect of PPM implantation remains ambiguous. Design One hundred sixty-eight patients who underwent TAVI from 2008 to 2012 were included. Patient characteristics, ECGs and PPM data were collected through medical records...
October 3, 2016: Scandinavian Cardiovascular Journal: SCJ
Arnar Geirsson, Anders Ahlsson, Anders Franco-Cereceda, Simon Fuglsang, Jarmo Gunn, Emma C Hansson, Vibeke Hjortdal, Kati Jarvela, Anders Jeppsson, Ari Mennander, Shahab Nozohoor, Christian Olsson, Anders Wickbom, Igor Zindovic, Tomas Gudbjartsson
OBJECTIVES: The Nordic Consortium for Acute Type A Aortic Dissection (NORCAAD) is a collaborative effort of Nordic cardiac surgery centers to study acute type A aortic dissection (ATAAD). Here, we outline the overall objectives and the design of NORCAAD. DESIGN: NORCAAD currently consists of eight centers in Denmark, Finland, Iceland and Sweden. Data was collected for patients undergoing surgery for ATAAD from 2005 to 2014. A total of 194 variables were retrospectively collected including demographics, past medical history, preoperative medications, symptoms at presentation, operative variables, complications, bleeding and blood transfusions, need for late reoperations, 30-day mortality and long-term survival...
September 26, 2016: Scandinavian Cardiovascular Journal: SCJ
Espen Fengsrud, Anders Englund, Anders Ahlsson
OBJECTIVES: To study pre- and postoperative atrial fibrillation and its long-term effects in a cohort of aortocoronary bypass surgery patients. DESIGN: Altogether 615 patients undergoing aortocoronary bypass graft surgery in 1999-2000 were studied. Forty-four (7%) had preoperative atrial fibrillation. Postoperative atrial fibrillation occurred in 165/615 patients (27%) while 406/615 patients (66%) had no atrial fibrillation. After a median follow-up of 15 years, symptoms and medication in survivors were recorded, and cause of death in the deceased was obtained...
September 22, 2016: Scandinavian Cardiovascular Journal: SCJ
Inger Njølstad, Ellisiv B Mathiesen, Henrik Schirmer, Dag Steinar Thelle
The rapid increase of coronary heart disease mortality in Northern Norway during 1951-1970 was why the newly established University of Tromsø decided to start a study to identify major operating cardiovascular risk factors. The first Tromsø survey in 1974 suggested that the relatively high cardiovascular mortality was associated with elevated cholesterol levels and high prevalence of smoking, while high-density-lipoprotein-cholesterol (HDL-C) was identified as a preventive factor. After 1974, six more surveys including both genders (aged 20 to 89 years) were undertaken...
September 21, 2016: Scandinavian Cardiovascular Journal: SCJ
Thor Edvardsen, Sebastian I Sarvari, Kristina H Haugaa
Knowledge about myocardial function is important for diagnosis, treatment and prediction of the majority of all cardiac diseases. Ejection fraction (EF) by echocardiography has been the preferred diagnostic tool for these purposes, but do have some important limitations. Strain imaging has emerged as a relatively new and important echocardiographic method that will give cardiologists incremental and additional information to EF in several important diseases affecting the myocardium. This paper will give the readers a brief overview on how and when the clinicians can use strain imaging by echocardiography in their daily practice...
September 21, 2016: Scandinavian Cardiovascular Journal: SCJ
Christian E Rex, Johan Heiberg, Kaj-Erik Klaaborg, Vibeke E Hjortdal
PURPOSE: Transcatheter aortic valve implantation (TA-TAVI) is a well-established treatment for aortic valve stenosis in high-risk patients and indications have been continuously expanding to include also intermediate-risk patients. However, in low-risk patients, experiences are still sparse and although clinical outcomes have been shown favorable, HRQoL has remained unexplored. The aim of this report was to describe the long-term health-related quality-of-life (HRQoL) in low-risk patients randomized to TA-TAVI or surgical aortic valve replacement (SAVR)...
September 10, 2016: Scandinavian Cardiovascular Journal: SCJ
Salim Barywani, Max Petzold
OBJECTIVE: A substantial part of deaths and readmissions in octogenarians with acute coronary syndrome (ACS) is assumed to be of non-cardiovascular causes. However, limited data on cause-specific long-term mortality and hospital readmissions are available. This study was aimed to investigate 5-year cause-specific deaths and re-hospitalizations as well as their prognostic predictors among octogenarians with ACS managed with percutaneous coronary intervention (PCI). METHODS: A total of 181 octogenarians managed with PCI on ACS indication during 2006-2007 at Sahlgrenska University Hospital were included...
September 5, 2016: Scandinavian Cardiovascular Journal: SCJ
Kevin Kris Warnakula Olesen, Trine Ørhøj Barkholt, Michael Maeng
PURPOSE: Coronary angiography provides no details on underlying pathology in acute coronary syndromes (ACS). Optical coherence tomography (OCT) can visualize coronary atherosclerosis, thrombus formation, and plaque rupture in patients with myocardial infarction (MI) where coronary angiography is unclear. MATERIALS AND METHODS: We present a case series containing 6 young patients with ACS, 4 of them due to non-obstructive thrombus, in whom the operators refrained from stent implantation despite an identifiable culprit lesion with OCT-validated thrombus formation...
September 5, 2016: Scandinavian Cardiovascular Journal: SCJ
Vesa Anttila, Henri Haapanen, Fredrik Yannopoulos, Johanna Herajärvi, Tuomas Anttila, Tatu Juvonen
In remote ischemic preconditioning (RIPC) short periods of non-lethal ischemia followed by reperfusion of tissue or organ prepare remote tissue or organ to resist a subsequent more severe ischemia-reperfusion injury. The signaling mechanism of RIPC can be humoral communication, neuronal stimulation, systemic modification of circulating immune cells, and activation of hypoxia inducible genes. Despite promising evidence from experimental studies, the clinical effects of RIPC have been controversial. Heterogeneity of inclusion and exclusion criteria and confounding factors such as comedication, anesthesia, comorbidities, and other risk factors may have influenced the efficacy of RIPC...
September 5, 2016: Scandinavian Cardiovascular Journal: SCJ
Emma C Hansson, Anders Jeppsson
No abstract text is available yet for this article.
September 2, 2016: Scandinavian Cardiovascular Journal: SCJ
Marcus Ståhlberg, Frieder Braunschweig, Fredrik Gadler, Lars Mortensen, Lars H Lund, Cecilia Linde
Heart failure (HF) is considered as an epidemic and affects 2% of the population in the Western world. About 15-30% of patients with HF and reduced ejection fraction (HFrEF) also have prolonged QRS duration on the surface ECG, most commonly as a result of left-bundle branch block (LBBB). Increased QRS duration is a marker of a dyssynchronous activation, and subsequent contraction, pattern in the left ventricle (LV). When dyssynchrony is superimposed on the failing heart it further reduced systolic function and ultimately worsens outcome...
August 30, 2016: Scandinavian Cardiovascular Journal: SCJ
David O Arnar, Karl Andersen, Gudmundur Thorgeirsson
In the past ten years large scale genotyping has led to discoveries of sequence variants that confer risk of many common and complex diseases. Due to pioneering work done, in large part, at deCODE genetics in Reykjavik, discoveries from Iceland have contributed substantially to key advances in population genetics. In cardiovascular medicine a number of discoveries have been made, uncovering sequence variants that are associated with disorders such as coronary artery disease, atrial fibrillation, sick sinus syndrome, peripheral vascular disease, aortic aneurysm and ischemic stroke...
August 30, 2016: Scandinavian Cardiovascular Journal: SCJ
Jørund Langørgen, Marta Ebbing, Jannicke Igland, Jan Erik Nordrehaug, Stein Emil Vollset, Anne Kask, Grethe S Tell, Ottar Nygård
OBJECTIVES: The third Universal 2012 definition of myocardial infarction (MI) has not been compared to the Universal 2007 definition with regard to the number of cases identified, classification and mortality. DESIGN: We examined potential MI events according to the two universal definitions in 1494 patients admitted to the University hospital during the 12 months. Patients were included either because of an MI discharge diagnosis (815 patients) or due to elevated troponin I levels without an MI discharge diagnosis (679 patients)...
August 2016: Scandinavian Cardiovascular Journal: SCJ
David Waldenhjort, Piotr Sobocinski Doliwa, Mahbubul Alam, Viveka Frykman-Kull, Johan Engdahl, Mårten Rosenqvist, Hans Persson
OBJECTIVE: In patients with a prior stroke or transient ischemic attack (TIA) and atrial fibrillation anticoagulant treatment is indicated. This study's purpose was to investigate if echocardiography can predict unknown AF in patients after stroke. DESIGN: Prospectively, 174 stroke/TIA patients without diagnosed AF underwent echocardiographic evaluation including tissue Doppler imaging (TDI) focusing on functional parameters of the left atrium and left ventricular diastolic function...
August 2016: Scandinavian Cardiovascular Journal: SCJ
Göran Rådegran, Barbro Kjellström, Björn Ekmehag, Flemming Larsen, Bengt Rundqvist, Sofia Berg Blomquist, Carola Gustafsson, Roger Hesselstrand, Monica Karlsson, Björn Kornhall, Magnus Nisell, Liselotte Persson, Henrik Ryftenius, Maria Selin, Bengt Ullman, Kent Wall, Gerhard Wikström, Maria Willehadson, Kjell Jansson
OBJECTIVES: The Swedish Pulmonary Arterial Hypertension Register (SPAHR) is an open continuous register, including pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) patients from 2000 and onwards. We hereby launch the first data from SPAHR, defining baseline characteristics and survival of Swedish PAH and CTEPH patients. DESIGN: Incident PAH and CTEPH patients 2008-2014 from all seven Swedish PAH-centres were specifically reviewed...
August 2016: Scandinavian Cardiovascular Journal: SCJ
Pasi P Karjalainen, Matti Niemelä, Mikko Pietilä, Jussi Sia, Adam de Belder, Fernando Rivero-Crespo, Bernard de Bruyne, Wail Nammas
OBJECTIVES: The BASE-ACS trial demonstrated non-inferiority of titanium-nitride-oxide-coated bioactive stents (BAS), versus everolimus-eluting stents (EES), for major adverse cardiac events (MACE) at 1- and 2-year follow-up, in patients with acute coronary syndrome (ACS). We presented the 4-year outcome of the BASE-ACS trial. DESIGN: We randomized 827 patients with ACS to receive either BAS (417) or EES (410). MACE was a composite of cardiac death, non-fatal myocardial infarction (MI) or ischemia-driven target lesion revascularization (TLR) at 12-month follow-up...
August 2016: Scandinavian Cardiovascular Journal: SCJ
Juuso I Blomster, John O'Rourke, Preeti Choudhary, Aravinda Thiagalingam, Pramesh Kovoor, Julian Adler, Graham S Hillis, Clara K Chow
OBJECTIVE: Computed tomography coronary angiography (CTCA) has become a commonly used imaging modality in patients with suspected anginal symptoms but also in asymptomatic populations. This practice has raised concerns due to potential high radiation exposure in terms of adequate benefit to risk profile. DESIGN: Demographics and CTCA scan details were collected from a consecutive series of 586 patients referred to a single community radiology practice for a CTCA...
August 2016: Scandinavian Cardiovascular Journal: SCJ
Sikarin Upala, Anawin Sanguankeo, Soontharee Congrete, Veeravich Jaruvongvanich
BACKGROUND: Vitamin D deficiency increases risk of cardiovascular diseases, arterial stiffness, and endothelial dysfunction. We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) investigating the impact of vitamin D supplementation on arterial stiffness. METHODS: A comprehensive search of the databases of the Cochrane Central Register of Controlled Trials, MEDLINE, and EMBASE was performed from inception through November 2015...
August 2016: Scandinavian Cardiovascular Journal: SCJ
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