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Clinical Oral Investigations

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https://www.readbyqxmd.com/read/28536783/ph-influences-the-biocompatibility-of-methylene-blue-solutions
#1
David Jonathan Rodrigues Gusman, Luciano Tavares Angelo Cintra, Vivian Cristina Noronha Novaes, Henrique Rinaldi Matheus, Nathália Januario de Araujo, Juliano Milanezi de Almeida
OBJECTIVE: The aim of this study was to investigate the biocompatibility of methylene blue at different pH levels through the method of implantation in subcutaneous tissue. MATERIALS AND METHODS: Eighty-four sterilized polyethylene tubes were allocated in the subcutaneous tissue of 28 rats, each one receiving four tubes, set into four groups: group tube (G-T)-empty tube, fibrin group (G-F)-tube filled with fibrin sponge, group methylene blue pH 7 (G-MB/pH 7)-tube filled with fibrin sponge soaked by methylene blue (100 μg/ml) at pH 7...
May 23, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28536782/evaluation-of-metal-artefact-reduction-in-cone-beam-computed-tomography-images-of-different-dental-materials
#2
Polyane Mazucatto Queiroz, Matheus Lima Oliveira, Francisco Carlos Groppo, Francisco Haiter-Neto, Deborah Queiroz Freitas
OBJECTIVE: The aim of this study is to evaluate the efficacy of metal artefact reduction (MAR) in different dental materials with Picasso Trio cone-beam computed tomography (CBCT) scanner. MATERIALS AND METHODS: Three imaging phantoms were custom-made of acrylic resin. Each phantom presented three cylinders of the same material: dental amalgam alloy, gutta-percha or aluminium-copper alloy. CBCT scans were performed on Picasso Trio unit with and without MAR, and artefact expression (standard deviation of grey values) was obtained and compared by Kruskal-Wallis and Student-Newman-Keuls (post hoc) (α = 0...
May 23, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28536781/oral-health-status-in-adult-patients-with-newly-diagnosed-acute-leukemia
#3
Rilana Busjan, Justin Hasenkamp, Gerhard Schmalz, Rainer Haak, Lorenz Trümper, Dirk Ziebolz
BACKGROUND: The aim of this cross-sectional study was to evaluate the oral health of adult patients with newly diagnosed acute leukemia. METHODS: Patients with initially diagnosed acute myeloid (AML) or lymphocytic (ALL) leukemia and a matched healthy control (HC) group were included. The oral investigation comprised inspection of the oral mucosa; the decayed (D), missing (M), and filled (F) teeth (DMF-T) index; and a detailed periodontal status. Subgingival biofilm samples were analyzed (polymerase chain reaction) for the presence of selected potentially periodontal pathogenic bacteria...
May 23, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28534125/salivary-glands-abnormalities-in-oculo-auriculo-vertebral-spectrum
#4
Davide Brotto, Renzo Manara, Stefania Vio, Sara Ghiselli, Elena Cantone, Rodica Mardari, Irene Toldo, Valentina Stritoni, Alessandro Castiglione, Elisa Lovo, Patrizia Trevisi, Roberto Bovo, Alessandro Martini
BACKGROUND: Feeding and swallowing impairment are present in up to 80% of oculo-auriculo-vertebral spectrum (OAVS) patients. Salivary gland abnormalities have been reported in OAVS patients but their rate, features, and relationship with phenotype severity have yet to be defined. MATERIAL AND METHODS: Parotid and submandibular salivary gland hypo/aplasia was evaluated on head MRI of 25 OAVS patients (16 with severe phenotype, Goldenhar syndrome) and 11 controls...
May 22, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28501945/macrophage-polarization-differs-between-apical-granulomas-radicular-cysts-and-dentigerous-cysts
#5
Manuel Weber, Tilo Schlittenbauer, Patrick Moebius, Maike Büttner-Herold, Jutta Ries, Raimund Preidl, Carol-Immanuel Geppert, Friedrich W Neukam, Falk Wehrhan
OBJECTIVES: Apical periodontitis can appear clinically as apical granulomas or radicular cysts. There is evidence that immunologic factors are involved in the pathogenesis of both pathologies. In contrast to radicular cysts, the dentigerous cysts have a developmental origin. Macrophage polarization (M1 vs M2) is a main regulator of tissue homeostasis and differentiation. There are no studies comparing macrophage polarization in apical granulomas, radicular cysts, and dentigerous cysts...
May 13, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28488057/the-impact-of-rapid-maxillary-expansion-on-maxillary-first-molar-root-morphology-of-cleft-subjects
#6
Lucas Cardinal, Gabriela da Rosa Zimermann, Fausto Medeiros Mendes, Ildeu Andrade, Dauro Douglas Oliveira, Gladys Cristina Dominguez
OBJECTIVES: The aim of this prospective cohort study was to determine the effects of rapid maxillary expansion (RME) on the first molar roots of cleft lip and palate subjects along different root development stages. MATERIALS AND METHODS: Thirty participants with unilateral cleft lip and palate were divided into three groups (n = 10), according to the type of expander used: Hyrax, iMini and Fan-type. A cone beam CT scan was performed before (T1) and 3 months after stabilization of the appliance (T2)...
May 9, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28451935/single-nucleotide-polymorphisms-in-genes-of-dopaminergic-pathways-are-associated-with-bruxism
#7
Gonzalo H Oporto, Thomas Bornhardt, Verónica Iturriaga, Luis A Salazar
OBJECTIVES: This research aimed to evaluate the frequency of single nucleotide polymorphisms (SNPs) in dopaminergic pathway genes (DRD1, DRD2, DRD3, DRD4, DRD5, and MAOB) in patients undergoing bruxism treatment and controls. SUBJECTS AND METHODS: Patients submitted to bruxism treatment were classified in awake bruxism (61 patients), sleep bruxism (26 patients), and awake-sleep bruxism (43 patients). Control group included 59 patients. Association between circadian manifestations of bruxism and SNPs was investigated using Fisher's exact test, chi-squared test, and calculating the odds ratios and their respective 95% confidence intervals...
April 27, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28434045/slow-drilling-speeds-for-single-drill-implant-bed-preparation-experimental-in-vitro-study
#8
R A Delgado-Ruiz, E Velasco Ortega, G E Romanos, S Gerhke, I Newen, J L Calvo-Guirado
AIMS: To evaluate the real-time bone temperature changes during the preparation of the implant bed with a single-drill protocol with different drill designs and different slow drilling speeds in artificial type IV bone. MATERIALS AND METHODS: For this experimental in vitro study, 600 implant bed preparations were performed in 10 bovine bone disks using three test slow drilling speeds (50/150/300 rpm) and a control drilling speed (1200 rpm). The temperature at crestal and apical areas and time variations produced during drilling with three different drill designs with similar diameter and length but different geometry were recorded with real-life thermographic analysis...
April 22, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28424878/oral-health-in-patients-with-renal-disease-a-longitudinal-study-from-predialysis-to-kidney-transplantation
#9
Karita M Nylund, Jukka H Meurman, Anna Maria Heikkinen, Jussi O Furuholm, Fernanda Ortiz, Hellevi M Ruokonen
OBJECTIVES: The aim of this longitudinal study was to compare the oral health of chronic kidney disease patients at the predialysis (baseline) and post-transplantation (follow-up) stages and to investigate differences in oral health between diabetic nephropathy and other kidney disease patients at follow-up. MATERIALS AND METHODS: Fifty-three kidney disease patients (34 men) aged 31-86 years were followed up to 157 months. Clinical and radiological oral examinations, salivary and laboratory analyses, and oral health behavior questionnaires were conducted at the predialysis and follow-up stages at Helsinki University Hospital, Finland...
April 20, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28417206/erratum-to-effect-of-the-addition-of-nano-sized-sodium-hexametaphosphate-to-fluoride-toothpastes-on-tooth-demineralization-an-in-vitro-study
#10
Giovanna Dalpasquale, Alberto Carlos Botazzo Delbem, Juliano Pelim Pessan, Gabriel Pereira Nunes, Luiz Fernando Gorup, Francisco Nunes Souza Neto, Emerson Rodrigues de Camargo, Marcelle Danelon
No abstract text is available yet for this article.
April 18, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28389903/aic-19th-international-congress-and-conseuro-clinical-procedures-and-digital-r-evolution-contemporary-synergies-in-conservative-restorative-dentistry
#11
(no author information available yet)
No abstract text is available yet for this article.
April 8, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28386810/erratum-to-pulp-bleeding-color-is-an-indicator-of-clinical-and-histohematologic-status-of-primary-teeth
#12
Naser Asl Aminabadi, Marziyeh Parto, Parya Emamverdizadeh, Zahra Jamali, Sajjad Shirazi
No abstract text is available yet for this article.
April 7, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28382465/significance-of-genetic-variations-in-developmental-enamel-defects-of-primary-dentition-in-polish-children
#13
Karolina Gerreth, Katarzyna Zaorska, Maciej Zabel, Michal Nowicki, Maria Borysewicz-Lewicka
OBJECTIVES: The aim of the study was to reveal the association between developmental defects of enamel (DDE) and single nucleotide polymorphisms (SNPs) in the ENAM, AMELX, AMBN, TUFT1, and TFIP11 genes. MATERIAL AND METHODS: The molecular analysis was carried out in 52 children, aged 10-42 months, from four nursery schools situated in the region of Poznan, Poland (26 individuals with hypomineralization and/or hypoplasia of enamel - "cases" and 26 unaffected children - "controls"), chosen from 262 individuals that had prior dental examination...
April 5, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28367601/effect-of-an-oral-healthcare-programme-on-care-staff-knowledge-and-attitude-regarding-oral-health-a-non-randomised-intervention-trial
#14
B Janssens, J Vanobbergen, M Lambert, J M G A Schols, L De Visschere
OBJECTIVES: The objective of the study was to evaluate the effect of an oral healthcare programme in nursing homes on care staff knowledge and attitude regarding oral health. METHODS: The study sample consisted of the nurses and nurses' aides from 63 nursing homes, which either received an oral healthcare programme including mobile dental care or were on a waiting list to receive this programme. A validated questionnaire completed at baseline and again after the study period assessed the care staff knowledge and attitude...
April 3, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28365810/a-retrospective-cephalometric-investigation-of-two-fixed-functional-orthodontic-appliances-in-class-ii-treatment-functional-mandibular-advancer-vs-herbst-appliance
#15
Gero Stefan Michael Kinzinger, Jörg Alexander Lisson, Linda Frye, Ulrich Gross, Jan Hourfar
OBJECTIVE: The objective of the study is to compare skeletal and dental changes in class II patients treated with fixed functional appliances (FFA) that pursue different biomechanical concepts: (1) FMA (Functional Mandibular Advancer) from first maxillary molar to first mandibular molar through inclined planes and (2) Herbst appliance from first maxillary molar to lower first bicuspid through a rod-and-tube mechanism. MATERIALS AND METHODS: Forty-two equally distributed patients were treated with FMA (21) and Herbst appliance (21), following a single-step advancement protocol...
April 1, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28365809/randomised-clinical-trial-to-evaluate-changes-in-dentine-tubule-occlusion-following-4%C3%A2-weeks-use-of-an-occluding-toothpaste
#16
Joon Seong, Charles P Parkinson, Maria Davies, Nicholas C A Claydon, Nicola X West
OBJECTIVES: The objective of this study is to determine whether a silicone impression material could precisely replicate dentine tubule changes following 4 weeks toothbrushing with occluding or non-occluding toothpaste and whether changes reflected hypersensitivity clinical assessment. MATERIALS AND METHODS: This was a single site, examiner blind, parallel, two treatment arm, randomised clinical trial. Participants were healthy, ≥18, with ≥1 sensitive tooth with exposed dentine, Schiff sensitivity score ≥2, and patent tubules with dentine occlusion score 4-5 as determined by scanning electron microscopy of replica impressions...
April 1, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28361171/reducing-dentine-hypersensitivity-with-nano-hydroxyapatite-toothpaste-a-double-blind-randomized-controlled-trial
#17
M Vano, G Derchi, A Barone, R Pinna, P Usai, U Covani
OBJECTIVES: The present randomized double-blind clinical trial aimed to compare the efficacy in reducing dentin hypersensitivity of a dentifrice formulation containing nano-hydroxyapatite with a fluoride dentifrice and a placebo. METHODS AND MATERIALS: One hundred and five subjects were recruited to participate in the study. A computer-generated random table with blocking to one of the three study treatments was used in order to have 35 subjects per group: (1) nano-hydroxyapatite 2% gel toothpaste fluoride free; (2) fluoride gel toothpaste; (3) placebo...
March 30, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28357643/raloxifene-but-not-alendronate-can-compensate-the-impaired-osseointegration-in-osteoporotic-rats
#18
Leonardo Perez Faverani, Tárik Ocon Braga Polo, Gabriel Ramalho-Ferreira, Gustavo Antonio Correa Momesso, Jaqueline Suemi Hassumi, Ana Cláudia Rossi, Alexandre Rodrigues Freire, Felippe Bevilacqua Prado, Eloá Rodrigues Luvizuto, Reinhard Gruber, Roberta Okamoto
OBJECTIVES: Alendronate and raloxifene, a bisphosphonate and a selective estrogen modulator, respectively, are established osteoporosis therapies. Current evidence suggests that simultaneous application of osteoporosis therapies modulates osseointegration. However, alendronate shows inconsistent findings and raloxifene has not been studied comprehensively. This study aimed to evaluate the bone dynamics and molecular and microstructural features at the peri-implant bone interface in osteoporotic rats...
March 29, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28357642/genome-wide-gene-expression-profiling-of-tongue-squamous-cell-carcinoma-by-rna-seq
#19
Hai Xia Zhang, Ou Sheng Liu, Chao Deng, Yan He, Ye Qian Feng, Jin An Ma, Chun Hong Hu, Zhan Gui Tang
OBJECTIVE: Tongue squamous cell carcinoma (TSCC) is significantly more malignant than other type of oral squamous cell carcinoma (OSCC). In this study, we aimed to identify specific global gene expression signatures of TSCC to investigate the more invasive behavior of the deeply infiltrating cancer. METHODS: Using RNA-seq technology, we detected gene expression of 20 TSCCs, 20 matched paratumor tissues, and 10 healthy normal mucosa tissues. Enrichment analysis of gene ontology (GO) and pathway was conducted using online tools DAVID for the dysregulated genes...
March 29, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28353023/efficacy-of-gum%C3%A2-hydral-versus-biot%C3%A3-ne%C3%A2-oralbalance-mouthwashes-plus-gels-on-symptoms-of-medication-induced-xerostomia-a-randomized-double-blind-crossover-study
#20
Anna Greta Barbe, Yasmin Schmidt-Park, Stefanie Hamacher, Sonja Henny Maria Derman, Michael Johannes Noack
OBJECTIVES: The objective of this study is to determine the efficacy of GUM® Hydral versus Biotène® Oralbalance (both a mouthwash plus gel) on the subjective burden and clinical symptoms of patients with medication-induced xerostomia. MATERIALS AND METHODS: Subjects (N = 40) with medication-induced xerostomia (minimum 4/10 mm visual analog scale [VAS]) were randomized to treatment with GUM Hydral or Biotène Oralbalance mouthwash, both with gel, for 28 days...
March 28, 2017: Clinical Oral Investigations
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