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Clinical Oral Investigations

Anwar B Bataineh, Yanal M Nusair, Rasha Q Al-Rahahleh
OBJECTIVES: There is significant evidence that articaine and lidocaine buccal injections alone are sufficient for painless extraction of maxillary teeth. The aim of this study was to evaluate the extraction of permanent maxillary teeth and to compare pain control between articaine and lidocaine without palatal injection. MATERIALS AND METHODS: Group A received buccal and palatal injections of 2% lidocaine with 0.015 mg/ml epinephrine. Group B received only buccal local anesthetic injection of 2% lidocaine with 0...
November 12, 2018: Clinical Oral Investigations
Gustavo De-Deus, Felipe Gonçalves Belladonna, Arthur de Siqueira Zuolo, Renata Perez, Marco Simões Carvalho, Erick Miranda Souza, Ricardo Tadeu Lopes, Emmanuel João Nogueira Leal Silva
OBJECTIVE: To compare the effectiveness of the XP-endo Finisher instrument and passive ultrasonic irrigation (PUI) as final irrigation protocols on the removal of accumulated hard-tissue debris (AHTD) from oval-shaped canals using micro-computed tomographic (micro-CT) analysis. METHODS: Twenty mandibular incisors were anatomically pair-matched based on similar morphological dimensions (length, volume, aspect ratio, and configuration) through micro-CT analysis, prepared with Reciproc R25 instrument, scanned again, and assigned to one of the two experimental groups (n = 10), according to the final irrigation protocol: XP-endo Finisher and PUI...
November 12, 2018: Clinical Oral Investigations
Iria L Darriba, Paloma Cabirta Melón, Ana García Sartal, Ignacio Ríos Sousa, Víctor Alonso de la Peña
OBJECTIVE: The aim of this study is to determine whether prolonging the daytime at-home bleaching treatment by 1 week increases the bleaching effect without causing more side effects. MATERIALS AND METHODS: Fifty participants were randomly divided into two groups, (A) with a 14-day treatment and (B) with a 21-day treatment. A gel with 10% carbamide peroxide was applied for 2 h a day in custom trays. Color measurement was performed using a dental spectrophotometer on the right maxillary central incisor and the canine at baseline, at the end of treatment, and 1 and 6 months afterwards...
November 11, 2018: Clinical Oral Investigations
Yulan Wang, Yufeng Zhang, Anton Sculean, Dieter D Bosshardt, Richard J Miron
OBJECTIVES: The host-material interface has been a crucial relationship dictating the successful integration of biomaterials, including dental implants. The aim of the present study was to first investigate how macrophages behaved on various dental implant surfaces and thereafter to investigate their effect on soft tissue cells. MATERIALS AND METHODS: Macrophage adhesion, proliferation, and polarization towards either an M1 or M2 phenotype were investigated on six implant surfaces fabricated from pure titanium (Ti), pure zirconium (ZLA), and a titanium-zirconium (Ti-Zi) alloy of various surface topographies/chemistries...
November 10, 2018: Clinical Oral Investigations
Cigdem Atalayin, Huseyin Tezel, Zeynep Ergucu, Nimet Unlu, Guliz Armagan, Taner Dagci, Timur Kose
OBJECTIVE: The aim of this in vitro study is to evaluate the effects of resveratrol (RES) addition on the cytotoxicity and microtensile bond strength (μTBS) of different adhesives. MATERIALS AND METHODS: Five self-etching adhesives (G-aenial Bond-GC, Optibond All in One-Kerr, Gluma Self Etch-Kulzer, Clearfil S3 Bond-Kuraray, and Nova Compo-B Plus-Imicryl) were tested. They were applied to L-929 cell culture by the extract method. In the test groups, 0.5 μM RES (Sigma-Aldrich) was added into the medium...
November 10, 2018: Clinical Oral Investigations
Kathrin Becker, Katarina Jandik, Martin Stauber, Ilja Mihatovic, Dieter Drescher, Frank Schwarz
OBJECTIVES: Previous research revealed that autogenous tooth roots may be biologically equivalent to conventional bone grafts for lateral ridge augmentation. However, these analyses were limited to two dimensions, whereas healing is a volumetric process. The present study aimed at volumetrically assessing the microstructure following lateral ridge augmentation using extracted tooth roots. MATERIAL AND METHODS: The roots of differently conditioned maxillary premolars (i...
November 9, 2018: Clinical Oral Investigations
Lingling Shang, Wenyan Kang, Shutong Li, Shaohua Ge
OBJECTIVE: Fusobacterium nucleatum (F. nucleatum) is one of the most common bacteria involved in the initiation and progression of periodontal diseases. Pharmacological inhibitor of prolyl hydroxylases (PHDs), dimethyloxallyl glycine (DMOG), has been reported to exert anti-inflammatory effects. The aim of this investigation was to evaluate the role of DMOG in inflammatory cytokine production of human gingival fibroblasts (HGFs) stimulated with F. nucleatum. MATERIAL AND METHODS: HGFs were pretreated with 10, 50, and 100 μM DMOG for 24 h before infected with F...
November 8, 2018: Clinical Oral Investigations
Shin-Ichi Yamada, Hiroshi Kurita, Eiji Kondo, Shigeru Suzuki, Fumihiro Nishimaki, Nobuhiko Yoshimura, Masafumi Morioka, Shutaro Ishii, Takahiro Kamata
OBJECTIVES: The purpose of this study was to investigate the treatment outcomes and prognostic factors of medication-related osteonecrosis of the jaw (MRONJ) in Japanese patients. PATIENTS AND METHODS: Among 409 cases, treatment outcomes and prognostic factors were investigated in 275 patients. In statistical analyses, the 1-year cumulative curative rate was calculated with the Kaplan-Meier method, and significance was examined with the Wilcoxon test. Cox's proportional hazards regression analysis was used for the multivariate analysis...
November 8, 2018: Clinical Oral Investigations
Luis Felipe C S Carvalho, Marcelo Saito Nogueira, Tanmoy Bhattacharjee, Lazaro P M Neto, Lucas Daun, Thiago O Mendes, Ramu Rajasekaran, Maurílio Chagas, Airton A Martin, Luis Eduardo S Soares
OBJECTIVES: Investigate the biochemistry of in vivo healthy oral tissues through Raman spectroscopy. We aimed to characterize the biochemical features of healthy condition in oral subsites (buccal mucosa, lip, tongue, and gingiva) of healthy subjects. More specifically, we investigated Raman spectral characteristics and biochemical content of in vivo healthy tissues on Brazilian population. This characterization can be used to better define normal tissue and improve the detection of oral premalignant conditions in future studies...
November 7, 2018: Clinical Oral Investigations
Fabricio Batistin Zanatta, Alessandra Pascotini Grellmann, Stephanie Yuko Bessauer Tomitsuka, Maísa Casarin, Alexandre Weber, Raquel Pippi Antoniazzi, Cristiane Cademartori Danesi
OBJECTIVES: The aim of this study was to assess with histological and inflammatory analysis the use of flossing as a diagnostic method for detecting proximal gingivitis. MATERIAL AND METHODS: This is a diagnostic accuracy paper composed of two different studies. In the first study, three groups were identified based on papilla status: bleeding (+) with both methods (N = 26); bleeding (+) with dental floss, but no bleeding (-) with probing (N = 26); and no bleeding (-) with either method (N = 26)...
November 6, 2018: Clinical Oral Investigations
Ayfer Atav Ates, Aysin Dumani, Oguz Yoldas, Ilker Unal
OBJECTIVES: The aim of this study was to compare the postoperative pain after root canal treatment using a carrier-based obturation system and two different sealers. MATERIALS AND METHODS: In this prospective randomized clinical trial, 160 patients were selected. Patients with vital and devital teeth were randomized into four groups using a randomized block design with block sizes of 10 patients each. The groups were devital/vital teeth treated with iRoot SP sealer and devital/vital teeth treated with AH Plus sealer...
November 5, 2018: Clinical Oral Investigations
Francesco Iacono, Chiara Pirani, Ana Arias, Josè C de la Macorra, Luigi Generali, Maria Giovanna Gandolfi, Carlo Prati
OBJECTIVES: To evaluate the impact of a modified motion on the fatigue life of four brands of nickel-titanium (NiTi) reciprocating instruments. MATERIALS AND METHODS: Cyclic fatigue (CF) resistance of 160 instruments was evaluated in an artificial stainless-steel canal (90° angle, 5-mm radius of curvature). WaveOne and WaveOne Gold (Denstply Maillefer, Baillagues, Switzerland) and Reciproc and Reciproc Blue (VDW, Munich, Germany) were tested with two different motions: (1) X-Smart Plus (Denstply Maillefer) endodontic motor and (2) a 4:1 contra-angle with an experimental motion (EVO) with different rotation angles and based on a sinusoidal acceleration...
November 5, 2018: Clinical Oral Investigations
Michel Espinosa Klymus, Murilo Priori Alcalde, Rodrigo Ricci Vivan, Marcus Vinicius Reis Só, Bruno Carvalho de Vasconselos, Marco Antonio Hungaro Duarte
OBJECTIVES: The aim of this study was to evaluate the impact of body temperature on the cyclic fatigue resistance of different NiTi alloys used for the manufacturing of Reciproc Blue R25 (RB 25.08; VDW, Munich, Germany), X1 Blue File 25 (X1 25.06; MK Life Medical and Dental Products, Porto Alegre, Brazil) and WaveOne Gold Primary (WOG 25.07; Dentsply Maillefer, Ballaigues, Switzerland). MATERIALS AND METHODS: Sixty instruments of the RB 25.08, X1 25.06 and WOG 25...
November 5, 2018: Clinical Oral Investigations
Mariana Sales de Melo Soares, Cristine D'Almeida Borges, Marcos de Mendonça Invernici, Fabiani Gai Frantz, Luciene Cristina de Figueiredo, Sérgio Luis Scombatti de Souza, Mario Taba, Michel Reis Messora, Arthur Belém Novaes
OBJECTIVES: This study aims to investigate the additional influence of multiple applications of antimicrobial photodynamic therapy (aPDT) in smokers with chronic periodontitis. MATERIALS AND METHODS: Twenty smokers with chronic periodontitis were treated in a split-mouth design study with aPDT adjunct to Scaling and Root Planing (SRP) or SRP. aPDT was performed by using a laser light source with 660 nm wavelength associated with a photosensitizer. The applications were performed in four episodes (at days 0, 2, 7, and 14)...
November 3, 2018: Clinical Oral Investigations
Federico Berton, Fulvia Costantinides, Roberto Rizzo, Anna Franco, Jenny Contarin, Claudio Stacchi, Michele Maglione, Erika Visintini, Andrea Di Lenarda, Roberto Di Lenarda
OBJECTIVES: The aim of this prospective comparative clinical study was to evaluate the effect of oral anticoagulants on peri- and post-operative bleeding during simple single tooth extractions, comparing patients in treatment with vitamin K antagonists (VKAs) and patients assuming direct oral anticoagulants (DOACs). MATERIALS AND METHODS: Patients under oral anticoagulant therapy needing dental extraction were eligible for entering the study; patients were enrolled following inclusion and exclusion criteria and divided into VKAs and DOAC group according to the anticoagulation therapy...
November 3, 2018: Clinical Oral Investigations
T M Choi, L Kragt, J A C Goos, I M J Mathijssen, E B Wolvius, E M Ongkosuwito
OBJECTIVES: To determine whether the intramaxillary relationship of patients with Muenke syndrome and Saethre-Chotzen syndrome or TCF12-related craniosynostosis are systematically different than those of a control group. MATERIAL AND METHODS: Forty-eight patients (34 patients with Muenke syndrome, 8 patients with Saethre-Chotzen syndrome, and 6 patients with TCF12-related craniosynostosis) born between 1982 and 2010 (age range 4.84 to 16.83 years) that were treated at the Department of Oral Maxillofacial Surgery, Special Dental Care and Orthodontics, Children's Hospital Erasmus University Medical Center, Sophia, Rotterdam, the Netherlands, were included...
November 3, 2018: Clinical Oral Investigations
Fernando Oliveira Costa, Sérgio Diniz Ferreira, José Roberto Cortelli, Rafael Paschoal Esteves Lima, Sheila Cavalca Cortelli, Luís Otávio Miranda Cota
OBJECTIVES: Clinical and microbiological longitudinal changes in individuals with peri-implant mucositis (PM) with or without preventive maintenance therapy (PMT) have not been reported, especially in long periods of monitoring. This 5-year follow-up study aimed to assess the clinical and microbiological changes along time in individuals initially diagnosed with PM. MATERIALS AND METHODS: Eighty individuals diagnosed with PM (T1) and followed during 5 years (T2) were divided into one group with PMT during the study period (GTP; n = 39) and another group without PMT (GNTP; n = 41)...
November 1, 2018: Clinical Oral Investigations
Indiara W Henn, Clarissa C A Fernandez, Shruti Ravindramurthy, Diego G Bussaneli, Luciana R A Alanis, Alexandre R Vieira
No abstract text is available yet for this article.
November 1, 2018: Clinical Oral Investigations
Paula Maciel Brandão, José Antonio Poli de Figueiredo, Renata Dornelles Morgental, Roberta Kochenborger Scarparo, Rafael Chies Hartmann, Silvana Beltrami Gonçalves Waltrick, Ronaldo Araújo Souza
OBJECTIVES: The aim of this study was to evaluate the influence of foraminal enlargement on the healing of induced apical periodontitis in a rat model. MATERIAL AND METHODS: Periapical lesions were bilaterally induced in mandibular first molars of 24 Wistar rats, through root canals exposure to the oral environment during 3 weeks. Endodontic treatment was performed in the mesial canal of right molars, which were separated into two experimental groups (n = 12/group)...
November 1, 2018: Clinical Oral Investigations
S J Gartenmann, Y V Weydlich, S L Steppacher, C Heumann, T Attin, Patrick R Schmidlin
OBJECTIVE: To provide a systematic overview on the efficacy of green tea catechin as an adjunct to scaling and root planing (SRP) in terms of probing pocket depth (PPD). MATERIALS AND METHODS: A systematic literature search was performed using electronic databases in PubMed, Scopus, Medline, Cochrane, CINAHL, and Web of Science on randomized clinical trials up to January 2017. The research question was posed in accordance with PRISMA guidelines. RESULTS: The search provided 234 studies...
October 31, 2018: Clinical Oral Investigations
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