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Clinical Oral Investigations

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https://www.readbyqxmd.com/read/29222594/orthodontic-class-ii-1-treatment-efficiency-and-outcome-quality-of-herbst-multibracket-appliance-therapy
#1
N Bock, J Ruehl, S Ruf
OBJECTIVES: The aim of this retrospective investigation was to assess the efficiency and outcome quality of Class II:1 treatment (Tx). MATERIAL AND METHODS: The investigation is based on the evaluation of all Class II:1 patients that ever (1986-2014) started Tx with a Herbst appliance and subsequently a multibracket appliance (MBA) at the study center. Study casts from before Tx, after Herbst-MBA Tx, and (if available) after ≥ 24 months of retention were evaluated using the Peer Assessment Rating (PAR) index, the Ahlgren scale, and standard occlusal variables...
December 8, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29218422/how-frequent-does-peri-implantitis-occur-a-systematic-review-and-meta-analysis
#2
Mia Rakic, Pablo Galindo-Moreno, Alberto Monje, Sandro Radovanovic, Hom-Lay Wang, David Cochran, Anton Sculean, Luigi Canullo
OBJECTIVES: The objective of this study is to estimate the overall prevalence of peri-implantitis (PI) and the effect of different study designs, function times, and implant surfaces on prevalence rate reported by the studies adhering to the case definition of Sanz & Chapple 2012. MATERIAL AND METHODS: Following electronic and manual searches of the literature published up to February 2016, data were extracted from the studies fitting the study criteria. Meta-analysis was performed for estimation of overall prevalence of PI while the effects of the study design, function time, and implant surface type on prevalence rate were investigated using meta-regression method...
December 7, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29214378/the-effectiveness-of-two-types-of-mads-for-osa-therapy
#3
Francis Emma Verburg, Klara Hilda Alphonsine Bollen, Henk-Jan Donker, Gerbrand Johannes Cornelis Kramer
OBJECTIVES: The purpose of this study was to determine differences in effectiveness between two types of mandibular advancement device (MAD). MATERIAL AND METHODS: In this retrospective, cohort study, the two devices used were MAD type "Somnodent-Flex" (MAD 1) and MAD type "Herbst" (MAD 2). One hundred thirty-seven patients participated in this study, 67 patients were treated with MAD 1, and 70 patients with MAD 2. The indication MAD with obstructive sleep apnea (OSA) is based on a polysomnography test, in accordance with the CBO guidelines...
December 6, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29214377/validation-of-a-new-experimental-model-of-extrusive-luxation-on-maxillary-molars-of-rats-a-histological-study
#4
Luciana Artioli Costa, Luana Martins Cantanhede, Erika Martins Pereira, Marcelo Macedo Crivelini, Osmar Aparecido Cuoghi, Alex Luiz Pozzobon Pereira, Marcos Rogério de Mendonça
BACKGROUND/AIM: The aim of this study was to test and validate a new model of extrusive luxation trauma on maxillary first molars of rats. MATERIAL AND METHODS: Forty adult male rats (Rattus norvegicus albinus, Wistar; weight = 230-250 g), 45 days old, were divided into eight groups (n = 5): control groups, in which animals were not subjected to any procedure and waited 1 day (GC1D) or 3 days (GC3D) for euthanasia, and experimental groups, in which animals were subjected to forces of 1100cN, 1300cN, or 1500cN and waited 1 or 3 days for euthanasia (GT1100/1D, GT1100/3D, GT1300/1D, GT1300/3D, GT1500/1D, GT1500/3D)...
December 6, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29214376/polymer-infiltrated-ceramic-cad-cam-inlays-and-partial-coverage-restorations-3-year-results-of-a-prospective-clinical-study-over-5-years
#5
F A Spitznagel, K J Scholz, J R Strub, K Vach, P C Gierthmuehlen
OBJECTIVE: The aim of this prospective clinical 5-year study was to evaluate the long-term behavior of monolithic computer-aided design and computer-aided manufacturing (CAD/CAM)-fabricated minimally invasive polymer-infiltrated ceramic network (PICN) inlays and partial coverage restorations (PCR). MATERIAL AND METHODS: Posterior teeth of 47 patients were restored with 103 restorations (45 inlays, 58 PCRs). After defect-oriented preparations, monolithic PICN restorations of VITA Enamic were fabricated with a CAD/CAM system (inEoS blue/CEREC inLab MCXL) and adhesively bonded (Variolink II)...
December 6, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29209937/sugar-based-collagen-membrane-cross-linking-increases-barrier-capacity-of-membranes
#6
Po-Ju Chia-Lai, Anna Orlowska, Sarah Al-Maawi, Andre Dias, Yunxin Zhang, Xuejiu Wang, Niklas Zender, Robert Sader, C James Kirkpatrick, Shahram Ghanaati
OBJECTIVES: This study examines the permeability and barrier capacity of a sugar cross-linked resorbable collagen membrane ex vivo and in vivo. MATERIALS AND METHODS: In an ex vivo study, injectable platelet-rich fibrin (i-PRF), a peripheral blood-derived human leukocyte-and-platelet-rich plasma was used to analyze membrane permeability. in vivo subcutaneous implantation in Wistar rats (n = 4 per time point and group) was used to investigate the barrier capacity of the membrane...
December 6, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29197953/prolonged-use-of-alendronate-alters-the-biology-of-cranial-repair-in-estrogen-deficient-rats-associated-simultaneous-immunohistochemical-expression-of-tgf-%C3%AE-1-%C3%AE-er-and-bmpr1b
#7
Allan Fernando Giovanini, Giuliene Nunes de Sousa Passoni, Isabella Göhringer, Tatiana Miranda Deliberador, João Cesar Zielak, Carmem Lucia Muller Storrer, Thais Andrade Costa-Casagrande, Rafaela Scariot
OBJECTIVES: TGF-β1 is a cytokine that may induce both osteoneogenesis through Runx-2 or fibrosis via the transcription of α-smooth muscle actin (α-SMA). Because it has been previously known that alendronate increases the level of TGF-β1 and that under the usual condition of bone metabolism the estrogen may prevent the fibrotic effect of TGF-β1, the aim of this study was to evaluate if alendronate alters the cellular differentiation process post calvarial surgery in estrogen-deficient specimens...
December 2, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29196949/accuracy-and-eligibility-of-cbct-to-digitize-dental-plaster-casts
#8
Kathrin Becker, Ulf Schmücker, Frank Schwarz, Dieter Drescher
OBJECTIVES: Software-based dental planning requires digital casts and oftentimes cone-beam computed tomography (CBCT) radiography. However, buying a dedicated model digitizing device can be expensive and might not be required. The present study aimed to assess whether digital models derived from CBCT and models digitized using a dedicated optical device are of comparable accuracy. MATERIAL AND METHODS: A total of 20 plaster casts were digitized with eight CBCT and five optical model digitizers...
December 2, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29196948/fracture-behavior-of-all-ceramic-implant-supported-and-tooth-implant-supported-fixed-dental-prostheses
#9
Abdul Rahman Alkharrat, Marc Schmitter, Stefan Rues, Peter Rammelsberg
OBJECTIVES: In vitro investigation of the effects of fixed dental prosthesis (FDP) support and loading conditions on the fracture behavior of all-ceramic, zirconia-based FDP veneered with computer-aided design/computer-aided manufacturing (CAD/CAM)-manufactured lithium disilicate ceramic. MATERIALS AND METHODS: Based on a model for a 3-unit FDP in the molar region (tooth in region 15, implant in region 17), 16 identical zirconia frameworks were fabricated and veneered with milled lithium disilicate ceramic...
December 2, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29196947/effect-of-bleaching-agent-extracts-on-murine-macrophages
#10
Aletéia M M Fernandes, Polyana G F Vilela, Marcia C Valera, Carola Bolay, Karl Anton Hiller, Helmut Schweikl, Gottfried Schmalz
OBJECTIVES: The aim of this study was to evaluate the cytotoxicity and the influence of bleaching agents on immunologically cell surface antigens of murine macrophages in vitro. MATERIALS AND METHODS: RAW 264.7 cells were exposed to bleaching gel extracts (40% hydrogen peroxide or 20% carbamide peroxide) and different H2O2 concentrations after 1 and 24-h exposure periods and 1-h exposure and 23-h recovery. Tests were performed with and without N-acetyl cysteine (NAC) and buthionine sulfoximine (BSO)...
December 1, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29192349/placement-of-an-antibiotic-oral-pack-on-the-hard-palate-after-primary-cleft-palatoplasty-a-randomized-controlled-trial-into-the-effect-on-fistula-rates
#11
Rajgopal R Reddy, Srinivas Gosla Reddy, Bhavya Banala, Ewald M Bronkhorst, Ann W Kummer, Anne Marie Kuijpers-Jagtman, Stefaan J Bergé
OBJECTIVE: The objective of this study is to determine whether placement of an antibiotic oral pack on the hard palate reduces fistula rates after primary cleft palatoplasty. SUBJECTS AND METHODS: This study was a parallel blocked randomized controlled trial. The study consisted of two groups of 100 patients each with non-syndromic unilateral complete cleft lip, alveolus, and hard and soft palate that underwent primary palatoplasty. Group A had an oral pack placed on the hard palate for 5 days postoperatively while group B did not...
November 30, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29189950/cost-assessment-of-a-new-oral-care-program-in-the-intensive-care-unit-to-prevent-ventilator-associated-pneumonia
#12
Jérôme Ory, Charline Mourgues, Evelyne Raybaud, Russell Chabanne, Jean Christophe Jourdy, Fabien Belard, Renaud Guérin, Bernard Cosserant, Jean Sébastien Faure, Laure Calvet, Bruno Pereira, Dominique Guelon, Ousmane Traore, Laurent Gerbaud
OBJECTIVES: Ventilator-associated pneumonia (VAP) is the most frequent hospital-acquired infections in intensive care units (ICU). In the bundle of care to prevent the VAP, the oral care is very important strategies, to decrease the oropharyngeal bacterial colonization and presence of causative bacteria of VAP. In view of the paucity of medical economics studies, our objective was to determine the cost of implementing this oral care program for preventing VAP. MATERIALS AND METHODS: In five ICUs, during period 1, caregivers used a foam stick for oral care and, during period 2, a stick and tooth brushing with aspiration...
November 30, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29188452/bisphosphonates-hinder-osteoblastic-osteoclastic-differentiation-in-the-maxillary-sinus-mucosa-derived-stem-cells
#13
Jun Zhang, Jaesuh Park, Jung-Woo Lee, Yong-Dae Kwon, Eun-Cheol Kim
OBJECTIVES: Although bisphosphonates (BPs) are known to be associated with osteonecrosis of the maxilla, the precise effects of BPs on bone metabolism in human maxillary sinus mucosal cells (HMSMCs) are not yet known. The purposes of this study were to examine the effects of the BPs zoledronate (ZOL) and alendronate (ALN) on osteoblastic and osteoclastic differentiation in HMSMCs and to investigate the signaling pathways involved. MATERIALS AND METHODS: The effects of ZOL and ALN were assessed for osteoblast differentiation by alkaline phosphatase (ALP) activity, alizarin red staining, and RT-PCR for genes encoding Runx2 and osterix...
November 30, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29188451/pediatric-cleft-palate-patients-show-a-3-to-5-fold-increase-in-cumulative-radiation-exposure-from-dental-radiology-compared-with-an-age-and-gender-matched-population-a-retrospective-cohort-study
#14
Reinhilde Jacobs, Ruben Pauwels, William C Scarfe, Carl De Cock, Karl Dula, Guy Willems, An Verdonck, Constantinus Politis
OBJECTIVE: The objective of the study was to compare estimates of pediatric cumulative exposure and lifetime attributable risk (LAR) of radiation-induced cancer from dental radiology between cleft palate (CP) subjects and age- and gender-matched controls (non-CP), with and without orthodontic treatment. MATERIALS AND METHODS: The radiation exposure frequency of CP subjects and non-CP controls with and without orthodontic treatment was compared for two-dimensional radiography (intra-oral, panoramic and cephalometric radiography), computed tomography (CT), and cone-beam CT (CBCT) using cumulative radiation dose as an estimate...
November 29, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29185146/lack-of-association-between-enam-gene-polymorphism-and-dental-caries-in-primary-and-permanent-teeth-in-czech-children
#15
Petra Borilova Linhartova, Tereza Deissova, Kristina Musilova, Lenka Zackova, Martina Kukletova, Lubomir Kukla, Lydie Izakovicova Holla
OBJECTIVES: The enamelin gene (ENAM) polymorphism (rs12640848) was recently associated with dental caries in primary teeth in Polish children. The aims of the present study were to prove this association in primary dentition and to find a possible effect of this variant on caries development in permanent dentition in Czech children. MATERIALS AND METHODS: This study comprised 905 Czech children. Totally, 187 children aged 2-6 years with primary dentition [78 healthy subjects (with decayed/missing/filled teeth, dmft = 0) and 109 patients with early childhood caries (ECC; dmft ≥ 1)] were included in this case-control study...
November 28, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29185145/development-of-a-novel-bioactive-glass-for-air-abrasion-to-selectively-remove-orthodontic-adhesives
#16
Ayam A Taha, Robert G Hill, Padhraig S Fleming, Mangala P Patel
OBJECTIVES: To develop a novel, bioactive glass for removing residual orthodontic adhesive via air-abrasion, following bracket debonding, and to evaluate its effectiveness against a proprietary bioactive glass 45S5(Sylc™)-air-abrasion, and a slow-speed tungsten carbide (TC) bur. MATERIALS AND METHODS: Three glasses were prepared and their bioactivity was proved. One novel glass (QMAT3) was selected due to its appropriate hardness, lower than that of enamel/45S5(Sylc™)...
November 28, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29185144/bond-strength-of-adhesive-systems-to-sound-and-demineralized-dentin-treated-with-bioactive-glass-ceramic-suspension
#17
Renata Costa de Morais, Renata Espíndola Silveira, Michelle Chinelatti, Saulo Geraldeli, Fernanda de Carvalho Panzeri Pires-de-Souza
OBJECTIVE: The objective of this study was to evaluate the effect of a Biosilicate®, associated with dentin adhesive system, on microtensile bond strength (μTBS) to sound and demineralized dentin. MATERIALS AND METHODS: Eighty sound-extracted molars had their middle occlusal dentin exposed. In forty teeth, dentin was artificially demineralized (pH cycling). Sound and demineralized dentin teeth were separated into four groups (n = 10), according to the substrate treatment before restoration: Group 1-total-etching adhesive Adper TM Single bond 2 (ASB) + Biosilicate®, Group 2-ASB (without Biosilicate®), Group 3-AdheSE self-etching adhesive system (AdSE) + Biosilicate®, and Group 4-AdSE (without Biosilicate®)...
November 28, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29177814/orofacial-manifestations-in-outpatients-with-anorexia-nervosa-and-bulimia-nervosa-focusing-on-the-vomiting-behavior
#18
Maria Lourenço, Álvaro Azevedo, Isabel Brandão, Pedro S Gomes
OBJECTIVE: This case-control study aims to evaluate the oral health status and orofacial problems in a group of outpatients with eating disorders (ED)-either anorexia nervosa (AN) or bulimia nervosa (BN)-further focusing on the influence of vomit. MATERIALS AND METHODS: Fifty-five women outpatients with AN or BN diagnosis were invited to participate, of which 33 agreed. ED outpatients and matched controls were submitted to a questionnaire and clinical oral examination...
November 25, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29177813/micro-ct-evaluation-of-voids-using-two-root-filling-techniques-in-the-placement-of-mta-in-mesial-root-canals-of-vertucci-type-ii-configuration
#19
Ali Keleş, Mahmoud Torabinejad, Cangül Keskin, Dongjin Sah, İsmail Uzun, Hatice Alçin
OBJECTIVE: The present study aims to compare two mineral trioxide aggregate (MTA) placement techniques, manual compaction and ultrasonic activation of manually compacted MTA, with warm vertical compaction (WVC) for orthograde obturation of mesial root canals of mandibular first molars showing Vertucci type II root canal configuration. MATERIALS AND METHODS: Thirty roots were selected according to their micro-CT scanned images. Root canals were chemomechanically prepared using Reciproc R25 and NaOCl using EndoVac...
November 25, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29151196/oral-cancer-radiotherapy-affects-enamel-microhardness-and-associated-indentation-pattern-morphology
#20
R Seyedmahmoud, Y Wang, G Thiagarajan, J P Gorski, R Reed Edwards, J D McGuire, M P Walker
OBJECTIVES: The aim of this study is to determine the effects of in vitro and in vivo high-dose radiotherapy on microhardness and associated indentation pattern morphology of enamel. MATERIALS AND METHODS: The inner, middle, and outer microhardness of enamel was evaluated using three experimental groups: control (non-radiated); in vitro irradiated; in vivo irradiated. In vitro specimens were exposed to simulated radiotherapy, and in vivo specimens were extracted teeth from oral cancer patients previously treated with radiotherapy...
November 18, 2017: Clinical Oral Investigations
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