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International Journal of Tuberculosis and Lung Disease

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https://www.readbyqxmd.com/read/28513421/clinical-and-bacteriological-characteristics-associated-with-clustering-of-multidrug-resistant-tuberculosis
#1
J-Y J-Y Feng, L G Jarlsberg, K Salcedo, J Rose, M Janes, S-Y G Lin, D H Osmond, K C Jost, M K Soehnlen, J Flood, E A Graviss, E Desmond, P K Moonan, P Nahid, P C Hopewell, M Kato-Maeda
<h2>SETTING:</h2><p>The impact of the genetic characteristics of Mycobacterium tuberculosis on the clustering of multidrug-resistant tuberculosis (MDR-TB) has not been analyzed together with clinical and demographic characteristics.</p><h2>OBJECTIVE:</h2><p>To determine factors associated with genotypic clustering of MDR-TB in a community-basedstudy.</p><h2>DESIGN:</h2><p>We measured the proportion of clustered cases among MDR-TB patients and determined the impact of clinical and demographic characteristics and that of three M...
May 16, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28303781/delays-in-diagnosis-and-treatment-of-pulmonary-tuberculosis-in-afb-smear-negative-patients-with-pneumonia
#2
Z X Zhang, L-H Sng, Y Yong, L M Lin, T W Cheng, N H Seong, F K Yong
<h2>BACKGROUND:</h2><p>Diagnostic and treatment delays increase the severity and transmission of pulmonary tuberculosis (PTB). This study aimed to evaluate TB diagnostic and treatment delays in acid-fast bacilli (AFB) smear-negative patients.</p><h2>METHODS:</h2><p>This was a retrospective observational study. Patients with positive AFB culture of <i>Mycobacterium tuberculosis</i> complex (MTC) were selected from among hospitalised patients with a diagnosis of pneumonia...
March 16, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28482968/resilience-and-extensively-drug-resistant-tuberculosis-the-unlikely-ally
#3
E Delgado, I Monedero, R Bhavaraju
Despite recent advances and well-known treatment options, cure rates for resistant tuberculosis (TB) cases remain extraordinarily low. We present in first person the case of a patient who suffered from TB for over 7 years, and travelled to four countries in search of a cure. This experience shows how resistance patterns worsen under poor programme conditions and illustrates many of the obstacles faced by patients to obtain appropriate care: late diagnosis, lack of experienced care capacity and drug availability, and absence of psychosocial support during toxic and lengthy regimens...
June 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28482967/prevalence-of-asthma-and-allergies-in-13-14-year-old-adolescents-from-luanda-angola
#4
M Arrais, O Lulua, F Quifica, J Rosado-Pinto, J M R Gama, L Taborda-Barata
SETTING: The few epidemiological studies on asthma and allergic diseases performed in Africa have shown that the prevalence of these diseases is high or increasing. No such studies have been performed in Angola. OBJECTIVE: To determine the prevalence of asthma and other allergic diseases in Angolan adolescents. DESIGN: This was a descriptive, observational, cross-sectional study in the province of Luanda, Angola, using the International Study of Asthma and Allergies in Childhood study methodology in adolescents aged 13 and 14 years...
June 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28482966/household-air-pollution-and-lung-function-in-indian-adults-a-cross-sectional-study
#5
M Dave, A S Ahankari, P R Myles, P Arokiasamy, P Khobragade, K Mortimer, A W Fogarty
Exposure to air pollution produced by cooking is common in developing countries, and represents a potentially avoidable cause of lung disease. Cross-sectional data were collected by the World Health Organization's Study on Global AGEing and Adult Health conducted in India between 2007 and 2010. Exposure to biomass cooking was also associated with a decrease in forced expiratory volume in 1 s (FEV1) (-70 ml, 95%CI -111 to -30) and FEV1/FVC (forced vital capacity) ratio (-0.025, 95%CI -0.035 to -0.015) compared to those who were not exposed...
June 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28482965/the-diagnostic-utility-of-pleural-fluid-adenosine-deaminase-for-tuberculosis-in-a-low-prevalence-area
#6
P Sivakumar, L Marples, R Breen, L Ahmed
BACKGROUND: Pleural fluid adenosine deaminase (pfADA) is not routinely measured in patients with undiagnosed pleural effusion due to limited evidence of its diagnostic utility in areas of low tuberculosis (TB) prevalence. METHODS: We conducted a retrospective consecutive case series analysis of all patients who underwent pfADA testing from 2009 to 2015 at a tertiary service pleural centre in south London. Using receiver operating characteristic (ROC) curve analysis, we identified the optimal threshold at which maximal sensitivity and specificity were achieved...
June 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28482964/the-sensitivity-of-the-quantiferon-%C3%A2-tb-gold-plus-assay-in-zambian-adults-with-active-tuberculosis
#7
L Telisinghe, M Amofa-Sekyi, K Maluzi, D Kaluba-Milimo, M Cheeba-Lengwe, K Chiwele, B Kosloff, S Floyd, S-L Bailey, H Ayles
SETTING AND OBJECTIVE: To investigate the sensitivity of the new interferon-gamma release assay (IGRA), QuantiFERON®-TB Gold Plus (QFT-Plus), for active TB (used as a surrogate for latent tuberculous infection) in a Zambian TB clinic. DESIGN: Consecutive smear or Xpert® MTB/RIF-positive adult (age 18 years) pulmonary TB patients were recruited between June 2015 and March 2016. Venous blood was tested using QFT-Plus. The sensitivity was defined as the number positive divided by the total number tested...
June 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28482963/paradoxical-upgrading-reaction-in-extra-pulmonary-tuberculosis-association-with-vitamin-d-therapy
#8
D A Barr, A K Coussens, S Irvine, N D Ritchie, K Herbert, B Choo-Kang, D Raeside, D J Bell, R A Seaton
SETTING: Glasgow, Scotland, UK. BACKGROUND: Paradoxical reactions in tuberculosis (TB) are a notable example of our incomplete understanding of host-pathogen interactions during anti-tuberculosis treatment. OBJECTIVES: To determine risk factors for a TB paradoxical reaction, and specifically to assess for an independent association with vitamin D use. DESIGN: Consecutive human immunodeficiency virus (HIV) negative adult patients treated for extra-pulmonary TB were identified from an Extended Surveillance of Mycobacterial Infections database...
June 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28482962/isoniazid-monoresistant-tuberculosis-is-associated-with-poor-treatment-outcomes-in-durban-south-africa
#9
Y F van der Heijden, F Karim, G Mufamadi, L Zako, T Chinappa, B E Shepherd, F Maruri, M-Y S Moosa, T R Sterling, A S Pym
SETTING: A large tuberculosis (TB) clinic in Durban, South Africa. OBJECTIVE: To determine the association between isoniazid (INH) monoresistant TB and treatment outcomes. DESIGN: We performed a retrospective longitudinal study of patients seen from 2000 to 2012 to compare episodes of INH-monoresistant TB with those of drug-susceptible TB using logistic regression with robust standard errors. INH-monoresistant TB was treated with modified regimens...
June 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28482961/low-prevalence-of-malnourishment-among-household-contacts-of-patients-with-tuberculosis-in-guinea-bissau
#10
C B Patsche, F Rudolf, S W Mogensen, A Sifna, V F Gomes, S Byberg, C Wejse
SETTING: An urban demographic surveillance site in Bissau, the capital of Guinea-Bissau, West Africa.BACKGROUND We hypothesised that if previous malnutrition plays a part in acquiring active tuberculosis (TB) disease, households of TB cases would have a higher prevalence of malnutrition than those of healthy controls. DESIGN: A cross-sectional study comparing nutritional and socio-economic status of all newly diagnosed patients with TB in 2014 with household contacts (persons residing in the household of TB cases) and random controls...
June 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28482960/tuberculosis-disease-among-mexico-born-individuals-living-in-new-york-city-2001-2014
#11
N L Stennis, J S Meissner, D Bhavnani, B Kreiswirth, S Desai Ahuja
SETTING: Tuberculosis (TB) has decreased substantially in New York City (NYC), but progress has slowed in recent years. Continued declines will require novel approaches tailored to foreign-born populations. OBJECTIVE: To describe TB epidemiology among the Mexico-born population of NYC to inform interventions in this community. DESIGN: The study included NYC patients with TB disease identified from 2001 to 2014. Incidence rates were compared by country of birth groupings...
June 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28482959/tuberculosis-in-adolescents-and-young-adults-epidemiology-and-treatment-outcomes-in-the-western-cape
#12
K Snow, A C Hesseling, P Naidoo, S M Graham, J Denholm, K du Preez
SETTING: Western Cape Province, South Africa. OBJECTIVES: To characterise tuberculosis (TB) epidemiology, disease presentation and treatment outcomes among adolescents (age 10-19 years) and young adults (age 20-24 years) in the Western Cape. DESIGN: A retrospective, cross-sectional review of routine patient-level data from the Electronic TB Register (ETR.Net) for 2013. Site of TB disease, human immunodeficiency virus (HIV) status and TB treatment outcomes were analysed by 5-year age groups (<5, 5-9, 10-14, 15-19, 20-24 and 25 years of age)...
June 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28482958/care-seeking-and-treatment-related-delay-among-childhood-tuberculosis-patients-in-delhi-india
#13
A Kalra
OBJECTIVE: To examine delays in treatment initiation among child tuberculosis (TB) patients and to identify associated factors. METHOD: A multistage cluster random sampling strategy was used to select 175 parents/care givers of childhood TB patients from eight district TB centres covered by the Revised National Tuberculosis Control Programme in Delhi for interview in a cross-sectional survey. Binary logistic regression analysis was used to identify associated factors...
June 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28482957/pediatric-and-adolescent-tuberculosis-in-latvia-2011-2014-case-detection-diagnosis-and-treatment
#14
B Ziemele, R Ranka, I Ozere
OBJECTIVE: To perform a comprehensive analysis of case detection, diagnosis and treatment of tuberculosis (TB) in children and adolescents in Latvia, and to evaluate the utility of the current approach. DESIGN: A retrospective study of all Latvian children and adolescents diagnosed with TB from 1 January 2011 to 31 December 2014. RESULTS: Of 3081 patients diagnosed with TB during 2011-2014, 250 (8%) were aged <18 years, and 80% were identified through contact investigation...
June 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28482956/tuberculosis-in-migrants-in-low-incidence-countries-epidemiology-and-intervention-entry-points
#15
K Lönnroth, Z Mor, C Erkens, J Bruchfeld, R R Nathavitharana, M J van der Werf, C Lange
As tuberculosis (TB) rates continue to decline in native populations in most low TB incidence countries, the proportion of TB patients born outside their country of residence ('foreign-born') increases. Some low-incidence countries have experienced a substantial increase in TB rates related to recent increases in the number of asylum seekers and other migrants from TB-endemic countries. However, average TB rates among the foreign-born in low-incidence countries declined moderately in 2009-2015. TB in foreign-born individuals is commonly the result of reactivation of latent infection with Mycobacterium tuberculosis acquired outside the host country...
June 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28482955/an-overview-of-tuberculosis-and-migration
#16
P Dhavan, H M Dias, J Creswell, D Weil
With nearly one billion migrants worldwide, migration is both a dynamic and a divisive phenomenon facing the world today. Migrants are a heterogeneous group, and the conditions surrounding migration pathways often pose risks to the physical, mental and social well-being of migrants, with certain subgroups being more vulnerable than others. Several determinants of health and tuberculosis (TB) interplay to increase the vulnerability of migrants to tuberculous infection, TB disease and poor treatment outcomes, making them a key population for TB...
June 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28482954/multidrug-resistant-tuberculosis-treatment-programmes-insufficiently-consider-comorbid-mental-disorders
#17
I F Walker, S C Baral, X Wei, R Huque, A Khan, J Walley, J N Newell, H Elsey
The successful treatment of multidrug-resistant tuberculosis (MDR-TB) is a global health priority and a key pillar of the World Health Organization's (WHO's) End TB strategy. There has been significant global investment in diagnostic capabilities in recent years. However, we argue that the mental distress of those with MDR-TB and their families continues to be overlooked by TB programmes. Priorities in the End TB Strategy of 'patient-centred care' and 'patient support' are still to be delivered in practice in many low-income settings, and in particular consideration of mental distress...
June 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28482953/if-you-look-you-will-find-time-to-challenge-the-childhood-tuberculosis-paradigm
#18
James A Seddon, Robert P Gie
No abstract text is available yet for this article.
June 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28482952/behind-the-great-walls
#19
Otto D Schoch, Hans L Rieder
No abstract text is available yet for this article.
June 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28482951/migrant-health-and-tuberculosis
#20
Mario C Raviglione, Davide Mosca
No abstract text is available yet for this article.
June 1, 2017: International Journal of Tuberculosis and Lung Disease
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