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International Journal of Tuberculosis and Lung Disease

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https://www.readbyqxmd.com/read/28766486/treating-persistent-asthma-in-rural-rwanda-characteristics-management-and-24-month-outcomes
#1
H Habineza, C Mutumbira, B L Hedt-Gauthier, R Borg, N Gupta, N Tapela, S Dusabeyezu, G Ngoga, E Harerimana, E Mpanumusingo, E Ngabireyimana, E Rusingiza, G Bukhman
<h2>SETTING:</h2>In 2007, the Rwandan Ministry of Health, with support from Partners In Health, introduced a district-level non-communicable disease programme that included asthma care.<h2>OBJECTIVE:</h2>To describe the demographics, management and 24-month outcomes of asthma patients treated at three rural district hospitals in Rwanda.<h2>DESIGN:</h2>We retrospectively reviewed electronic medical records of asthma patients enrolled from January 2007 to December 2012, and extracted information on demographics, clinical variables and 24-month outcomes...
August 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28664827/smoking-behavior-and-beliefs-about-the-impact-of-smoking-on-anti-tuberculosis-treatment-among-health-care-workers
#2
M J Magee, L Darchia, M Kipiani, T Chakhaia, R R Kempker, N Tukvadze, C J Berg, H M Blumberg
<h2>SETTING:</h2>Tuberculosis (TB) health care facilities throughout Georgia.<h2>OBJECTIVE:</h2>To describe smoking behaviors among health care workers (HCWs) at TB facilities and determine HCWs' knowledge and beliefs regarding the impact of tobacco use on anti-tuberculosis treatment.<h2>DESIGN:</h2>Cross-sectional survey from May to December 2014 in Georgia. Adult HCWs (age ⩾18 years) at TB facilities were eligible. We administered a 60-question anonymous survey about tobacco use and knowledge of the effect of smoking on anti-tuberculosis treatment...
June 29, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28911367/dr-georges-bakaswa-ntambwe-1950-2016
#3
Alberto Piubello
No abstract text is available yet for this article.
October 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28911366/lophomonas-blattarum-co-infection-in-a-patient-with-multidrug-resistant-tuberculosis
#4
Chaman Thakur, S Verma, R S Negi, V Kumar, S Gupta, V Sharma
No abstract text is available yet for this article.
October 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28911365/osteomyelitis-and-arthritis-caused-by-mycobacterium-intracellulare-an-underestimated-diagnosis
#5
Paola Piccini, Elisabetta Venturini, Francesca Romano, Marco Di Maurizio, Claudio De Filippi, Chiara Azzari, Maurizio de Martino, Luisa Galli
No abstract text is available yet for this article.
October 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28911364/tb-iris-presenting-with-haemophagocytic-lymphohistiocytosis-in-a-non-hiv-infected-male
#6
Yu-Chao Tseng, Hsin-Yun Sun, Jui-Hung Tsai, Po-Pin Hung, Jann-Tay Wang
No abstract text is available yet for this article.
October 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28911363/bronchial-angles-are-associated-with-nodular-bronchiectatic-non-tuberculous-mycobacteria-lung-disease
#7
T Lee, J Y Park, H Y Lee, H-J Lim, J S Park, Y-J Cho, T J Kim, K W Lee, J H Lee, C-T Lee, H I Yoon
BACKGROUND: The nodular bronchiectatic (NB) form of non-tuberculous mycobacteria (NTM) lung disease usually involves the right middle lobe (RML) and the left upper lobe lingular segment. However, the reason underlying this preference is not known. METHODS: Fifty patients with NB NTM lung disease who had both positive NTM culture(s) and NB lesions in the RML or lingular segment on computed tomography (CT) of the chest, and 100 healthy subjects matched for sex, age, height and body weight with normal chest CT, were randomly selected...
October 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28911362/assessment-of-the-quality-of-anti-tuberculosis-medicines-in-almaty-kazakhstan-2014
#8
D Nabirova, G Schmid, R Yusupova, M Kantarbayeva, S I Ismailov, D Moffett, R W O Jähnke, J P Nuorti
SETTING: In 2009, the World Health Organization (WHO) conducted a survey of the quality of four anti-tuberculosis drugs in the former Soviet Union countries. Kazakhstan had the highest proportion of substandard drugs. OBJECTIVE: To assess the quality of anti-tuberculosis drugs used in Kazakhstan in 2014. DESIGN: Fourteen anti-tuberculosis drugs from the Almaty Interdistrict TB Dispensary were randomly selected and screened for quality using Global Pharma Health Fund Minilab™ testing...
October 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28911361/detecting-mycobacterium-tuberculosis-using-the-loop-mediated-isothermal-amplification-test-in-south-africa
#9
S Reddy, S Ntoyanto, Y Sakadavan, T Reddy, S Mahomed, M Dlamini, B Spooner, G Ramjee, A Coutsoudis, N Ngomane, K Naidoo, K Mlisana, P Kiepiela
SETTING: In South Africa, KwaZulu-Natal is the epicentre of the human immunodeficiency virus (HIV) epidemic, where approximately 70% of people with tuberculosis (TB) are co-infected with HIV. Undiagnosed TB contributes to high mortality in HIV-infected patients. Delays in diagnosing TB and treatment initiation result in prolonged transmission and increased infectiousness. OBJECTIVE: To evaluate the LoopampTM MTBC Detection kit (TB-LAMP; based on the loop-mediated isothermal amplification assay), smear microscopy and Xpert test with the gold standard of mycobacterial culture...
October 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28911360/evaluation-of-the-tb-lamp-assay-for-the-rapid-diagnosis-of-pulmonary-tuberculosis-in-northern-india
#10
R Yadav, N Sharma, R Khaneja, P Agarwal, A Kanga, D Behera, S Sethi
SETTING: A tertiary care hospital in North India. OBJECTIVE: To evaluate a commercial kit-based loop-mediated isothermal amplification (TB-LAMP) assay for the diagnosis of pulmonary tuberculosis (PTB). DESIGN: A total of 530 patients presenting with PTB symptoms were enrolled and one sputum sample was collected from each patient. The TB-LAMP assay (Loopamp™ MTBC Detection kit) was performed on the raw sputum sample. The remaining sample was used for smear microscopy and mycobacterial culture...
October 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28911359/interferon-gamma-response-to-the-treatment-of-active-pulmonary-and-extra-pulmonary-tuberculosis
#11
L Liang, R Shi, X Liu, X Yuan, S Zheng, G Zhang, W Wang, J Wang, K England, L E Via, Y Cai, L C Goldfeder, L E Dodd, C E Barry, R Y Chen
BACKGROUND: Interferon-gamma (IFN-γ) release assays (IGRAs) are used to diagnose tuberculosis (TB) but not to measure treatment response. OBJECTIVE: To measure IFN-γ response to active anti-tuberculosis treatment. DESIGN: Patients from the Henan Provincial Chest Hospital, Henan, China, with TB symptoms and/or signs were enrolled into this prospective, observational cohort study and followed for 6 months of treatment, with blood and sputum samples collected at 0, 2, 4, 6, 8, 16 and 24 weeks...
October 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28911358/performance-of-nested-rt-pcr-on-csf-for-tuberculous-meningitis-diagnosis-in-hiv-infected-patients
#12
F A S Gualberto, M G Gonçalves, L O Fukasawa, A M Ramos Dos Santos, C T Sacchi, L H Harrison, D R Boulware, J E Vidal
SETTING: Timely diagnosis of tuberculous meningitis (TBM) in patients with human immunodeficiency virus (HIV) infection remains a challenge. Despite the current scale-up of the Xpert® MTB/RIF assay, other molecular diagnostic tools are necessary, particularly in referral centres in low- and middle-income countries without Xpert testing. OBJECTIVE: To determine the diagnostic performance of nested real-time polymerase chain reaction (nRT-PCR) in HIV-infected TBM patients categorised according to standardised clinical case definitions...
October 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28911357/pulmonary-tuberculosis-diagnostic-practices-among-people-living-with-the-human-immunodeficiency-virus-in-lesotho
#13
D E O'Connor, K Frederix, S Saito, L B Maama, Y Hirsch-Moverman, B Pitt, E Hayes-Larson, L Lebelo, M Shale, A A Howard
SETTING: Twelve health facilities in Berea District, Lesotho, that participated in the Start TB Patients on ART and Retain on Treatment (START) Study, a mixed-methods cluster-randomized trial evaluating a combination intervention package to improve early initiation of antiretroviral therapy (ART) and anti-tuberculosis treatment success among patients with tuberculosis (TB) and human immunodeficiency virus (HIV). OBJECTIVE: To assess TB and HIV diagnostic practices among TB-HIV patients...
October 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28911356/high-completion-rates-of-isoniazid-preventive-therapy-among-persons-living-with-hiv-in-swaziland
#14
L V Adams, N Mahlalela, E A Talbot, M Pasipamire, S Ginindza, M Calnan, S Haumba
SETTING: Five human immunodeficiency virus (HIV) care facilities in Swaziland. OBJECTIVE: To assess adherence and treatment completion of a 6-month course of isoniazid preventive therapy (IPT) provided to HIV-infected patients through a self-selected model of facility-based, community-based or peer-supported IPT delivery coordinated with antiretroviral refills. DESIGN: Prospective cohort study. RESULTS: Between February and August 2015, we enrolled 908 patients, with follow-up until February 2016...
October 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28911355/latent-tuberculous-infection-testing-among-hiv-infected-persons-in-clinical-care-united-states-2010-2012
#15
E J Reaves, N S Shah, A M France, S B Morris, S Kammerer, J Skarbinski, H Bradley
SETTING: Current guidelines recommend latent tuberculous infection (LTBI) testing at the time of human immunodeficiency virus (HIV) diagnosis and annually thereafter for persons at high risk of LTBI. OBJECTIVES: To estimate LTBI testing prevalence and describe the characteristics of HIV-infected persons who would benefit from annual LTBI testing. DESIGN: We estimated the proportions of LTBI testing among a nationally representative sample of HIV-infected adults in care between 2010 and 2012, and compared the patient characteristics of those with a positive LTBI test result to those with a negative result using χ2 tests...
October 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28911354/drug-resistance-patterns-among-extra-pulmonary-tuberculosis-cases-in-a-tertiary-care-centre-in-north-india
#16
S K Sharma, J Chaubey, B K Singh, R Sharma, A Mittal, A Sharma
BACKGROUND: xtra-pulmonary tuberculosis (EPTB) is a growing public health concern, and data on drug resistance are limited. MATERIAL AND METHODS: Specimens from 2468 clinically diagnosed EPTB patients received at the Intermediate Reference Laboratory (IRL) of a tertiary centre in India were subjected to Ziehl-Neelsen staining, Xpert® MTB/RIF testing, liquid culture and drug susceptibility testing (DST) using automated BACTEC MGIT™ 960™. Line-probe assay (LPA) was performed on all culture-positive isolates...
October 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28911353/persistently-high-early-mortality-despite-rapid-diagnostics-for-drug-resistant-tuberculosis-cases-in-south-africa
#17
K Schnippel, C Firnhaber, N Ndjeka, F Conradie, L Page-Shipp, R Berhanu, E Sinanovic
OBJECTIVE: To describe the timing and predictors of mortality among multidrug- and rifampicin-resistant tuberculosis (MDR/RR-TB) patients reported in the South African electronic drug-resistant TB register (EDRweb), 2012-2014. DESIGN: We present time-to-event survival analysis and Cox proportional hazards regression. Identity numbers were matched to the National Vital Statistics Register. RESULTS: Of the 20 653 patients included in the analysis (median age 35 years, interquartile range 28-43), over half were male (n = 10 944, 53...
October 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28911352/missed-opportunities-for-earlier-diagnosis-of-rifampicin-resistant-tuberculosis-despite-access-to-xpert-%C3%A2-mtb-rif
#18
E Mohr, J Daniels, O Muller, J Furin, B Chabalala, S J Steele, V Cox, T Dolby, G Ferlazzo, A Shroufi, L T Duran, H Cox
OBJECTIVE: To assess the proportion of rifampicin-resistant tuberculosis (RR-TB) patients with potential earlier RR-TB diagnoses in Khayelitsha, South Africa. DESIGN: We conducted a retrospective analysis among RR-TB patients diagnosed from 2012 to 2014. Patients were considered to have missed opportunities for earlier diagnosis if 1) they were incorrectly screened according to the Western Cape diagnostic algorithm; 2) the first specimen was not tested using Xpert® MTB/RIF; 3) no specimen was ever tested; or 4) the initial Xpert test showed a negative result, but no subsequent specimen was sent for follow-up testing in human immunodeficiency virus-positive patients...
October 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28911351/comprehensive-understanding-of-health-seeking-behaviour-among-pulmonary-tuberculosis-patients-in-china
#19
Y Jiang, B Cao, N Ohmagari, A-H Wu, Y-X Liu, L-P Guo
SETTING: In China, there were 918 000 tuberculosis (TB) cases in 2015 alone. The primary challenge facing TB control is the allocation of limited health care resources. OBJECTIVE: To gain a comprehensive understanding of the first choice of health care facility among Chinese patients with suspected pulmonary TB (PTB) and the number of visits required to make the diagnosis. DESIGN: Relevant full-text articles in three Chinese and one English literature databases up to November 2016 were reviewed...
October 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28911350/applying-the-care-group-model-to-tuberculosis-control-findings-from-a-community-based-project-in-mozambique
#20
A Brown, P Ernst, A Cambule, M Morrow, D Dortzbach, J E Golub, H B Perry
BACKGROUND: We describe the effectiveness of an innovative community-based social mobilization approach called Care Groups to improve the effectiveness of the national tuberculosis (TB) program by increasing TB testing and improving treatment outcomes in six districts of rural Mozambique. METHODS: The Care Group approach, which was implemented in a population of 218 191, enabled a facilitator to meet every 6 months with 10-12 community health volunteers (forming a Care Group) to share key TB messages and then for them to convey these messages over the subsequent 6 months to 10-12 households...
October 1, 2017: International Journal of Tuberculosis and Lung Disease
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