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International Journal of Tuberculosis and Lung Disease

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https://www.readbyqxmd.com/read/30621814/drug-resistance-in-extra-pulmonary-tuberculosis-in-south-korea-comparison-with-pulmonary-tuberculosis
#1
J Mok, B H Kang, H-J Kim, S J Lee, T Lee, H-K Lee, Y J Cho, D Jeon
<h2>OBJECTIVE:</h2>To compare the prevalence of and trends in drug resistance in extra-pulmonary tuberculosis (EPTB) and pulmonary tuberculosis (PTB).<h2>METHODS:</h2>We retrospectively analysed the results of phenotypic drug susceptibility testing (DST) in culture-confirmed TB patients from January 2010 to December 2014 at seven university hospitals in South Korea.<h2>RESULTS:</h2>Of 5599 patients included, 320 (5.7&percnt;) were classified in the EPTB group and 5279 (94...
January 8, 2019: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/30621813/process-measure-of-fast-tuberculosis-infection-control-demonstrates-delay-in-likely-effective-treatment
#2
H Le, N Nguyen, P Tran, N Hoa, N Hung, A Moran, H J Al Mossawi, N Kak, S Ahmedov, M B Brooks, E A Nardell, D B Tierney
<h2>SETTING:</h2>The tuberculous infection control strategy, FAST (Find cases Actively, Separate safely and Treat effectively), recommends prompt initiation of likely effective anti-tuberculosis treatment informed by Xpert&reg; MTB/RIF results.<h2>OBJECTIVE:</h2>To describe FAST implementation at Quang Nam Provincial TB and Lung Disease Hospital (QNH), Tam Ky, Viet Nam, using time to initiation of effective TB treatment as a process measure.<h2>DESIGN:</h2>Hospital logs were used to calculate the time to likely effective treatment in patients with pulmonary TB (PTB) hospitalised during the study period...
January 8, 2019: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/30621812/characteristics-of-miliary-tuberculosis-in-pregnant-women-after-in-vitro-fertilisation-and-embryo-transfer
#3
R Ye, C Wang, L Zhao, X Wu, Y Gao, H Liu
<h2>OBJECTIVE:</h2>To analyse the clinical characteristics of miliary tuberculosis (TB) in pregnant women after in vitro fertilisation and embryo transfer (IVF-ET).<h2>METHODS:</h2>Six pregnant women with miliary TB after IVF-ET between October 2010 and July 2015 were retrospectively analysed.<h2>RESULTS:</h2>The patients were aged between 29 and 39 years. Fever, cough and dyspnoea were the main symptoms, and started during the first and second trimesters of pregnancy. Erythrocyte sedimentation rate and C-reactive protein were increased...
January 8, 2019: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/30621811/nutritional-assessment-and-counselling-of-tuberculosis-patients-at-primary-care-in-india-do-we-measure-up
#4
M Bhargava, A Bhargava, K M Akshaya, S G Shastri, R Bairy, M Parmar, B N Sharath
<h2>SETTING:</h2>Dakshina Kannada District, coastal South India, under the Revised National Tuberculosis Control Programme (RNTCP).<h2>OBJECTIVE:</h2>To identify the potential and practices at primary health centres (PHCs) for the assessment of nutritional status of patients with tuberculosis (TB), the basic tools used to measure height and weight and the type of nutritional counselling provided.<h2>DESIGN:</h2>A cross-sectional study was conducted with physical verification of availability of height and weight measuring equipment...
January 8, 2019: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/30572983/pharmacokinetics-of-isoniazid-in-indian-children-with-tuberculosis-on-daily-treatment
#5
I Shah, N Jadhao, N Mali, S Deshpande, N Gogtay, U Thatte
<h2>OBJECTIVE:</h2>To assess the pharmacokinetics of isoniazid (INH) at 10 mg/kg/day among Indian children.<h2>METHODS:</h2>INH levels were estimated using liquid chromatography-tandem mass spectroscopy in 35 children aged 1&ndash;15 years on daily anti-tuberculosis treatment. Blood samples were collected 0, 1, 2, 3, 6 and 24 h after INH administration. The maximum concentration (Cmax ) and area under the curve (AUC0&ndash;24 ) were determined. The normal therapeutic range for Cmax is 3&ndash;5 &mu;g/ml...
December 20, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/30572982/impact-of-socio-economic-inequities-on-tuberculosis-in-a-southern-european-city-what-is-the-effect-of-the-recession
#6
A Prats-Uribe, A Orcau, J P Millet, J A Caylà
<h2>INTRODUCTION:</h2>Economic crises affect a population&apos;s health, particularly among the most deprived. The increase in health inequalities in the latest recession may have influenced the incidence of tuberculosis (TB). We analysed the effect of socio-economic inequities and recession on TB incidence in Barcelona, Spain.<h2>METHODS:</h2>We conducted a population-based incidence study of TB cases in Barcelona of patients who started treatment between 2003 and 2015. A multilevel interrupted time-series analysis was performed to analyse differences in incidence trends between the prerecession (until 2008) and recession periods...
December 20, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/30572979/interaction-between-c-tb-and-ppd-given-concomitantly-in-a-split-body-randomised-controlled-trial
#7
H H Aggerbeck, M Ruhwald, S T Hoff, P N Tingskov, E Hellstrom, M Malahleha, M Siebert, M Gani, A Diacon, Z Novelijc, P Andersen, K Dheda
<h2>SETTING:</h2>Seven tuberculosis (TB) clinics in South Africa.<h2>OBJECTIVE:</h2>As both purified protein derivative (PPD) and a Mycobacterium tuberculosis-specific skin test (CTb) contain region of difference 1 (RD1) antigens, we conducted a study to evaluate whether there was anyinteraction between the two during concomitant and separate administration in patients with newly diagnosed culture-positive TB.<h2>DESIGN:</h2>Adult patients with active TB (<italic>n</italic> &equals; 456, 20&percnt; human immunodeficiency virus infected) were randomised to receive only C-Tb, only PPD, or concomitant injection of both C-Tb and PPD using the Mantoux technique...
December 20, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/30567624/sputum-smear-microscopy-in-the-xpert-%C3%A2-mtb-rif-era
#8
A Van Deun, S Tahseen, D Affolabi, M A Hossain, M L Joloba, P K Angra, J C Ridderhof, B C de Jong, H L Rieder
A balanced perspective is advocated for the assessment and application of the most recent and the oldest diagnostic methods for pulmonary tuberculosis (TB)&mdash;the molecular Xpert&reg; MTB/RIF assay and microscopy for acid-fast bacilli. We discuss their respective merits and shortcomings and identify threats that may hamper their use in TB control. Neither test on its own provides all the information needed for diagnosis and treatment monitoring. Considering all aspects important for both individual patient care and disease control, neither seems &lsquo;better&apos; than the other...
December 19, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/30424825/how-tuberculosis-programs-can-navigate-the-world-of-social-health-insurance
#9
W A Wells, G Stallworthy, Z Balsara
<h2>SUMMARY</h2>Many countries with a high tuberculosis (TB) burden are adopting social health insurance (SHI) schemes. However, the national TB programs (NTPs) of these countries are only just starting to grapple with the effects of SHI on their operations. Here, we review the rationale for analyzing TB programs in light of the changes brought by SHI. We consider the influence of certain purchasing decisions on TB care and prevention, and the opportunities that SHI may present for NTPs to broaden private sector engagement, extract TB data across the health sector, and facilitate quality improvement efforts...
November 13, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/30366516/qtc-and-anti-tuberculosis-drugs-a-perfect-storm-or-a-tempest-in-a-teacup-review-of-evidence-and-a-risk-assessment
#10
I Monedero-Recuero, L Hernando-Marrupe, A Sánchez-Montalvá, V Cox, M Tommasi, J Furin, C-Y Chiang, M Quelapio, K G Koura, A Trébucq, X Padanilam, G Dravniece, A Piubello
<h2>SUMMARY</h2>Multidrug-resistant (MDR) and extensively drug-resistant tuberculosis (XDR-TB) are global concerns, with stagnant treatment success rates of roughly 54&percnt; and 30&percnt;, respectively. Despite adverse events associated with several DR-TB drugs, newly developed drugs and shorter regimens are bringing hope; recent concern has focused on drugs that prolong the corrected QT interval (QTc). QTc prolongation is a risk factor for torsades de pointe (TdP), a potentially lethal cardiac arrhythmia...
October 26, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/30606333/reviewers-volume-22-2018
#11
(no author information available yet)
No abstract text is available yet for this article.
December 1, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/30606332/walter-werner-holland-1929-2018
#12
Peter Burney
No abstract text is available yet for this article.
December 1, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/30606331/denny-mitchison-6-september-1919-2-july-2018
#13
Andrew Nunn
No abstract text is available yet for this article.
December 1, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/30606330/adriaan-manten-1918-2017
#14
Jakko van Ingen
No abstract text is available yet for this article.
December 1, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/30606329/pulmonary-mucormycosis-with-bronchial-fistula-successfully-treated-with-bronchoscopic-and-medical-therapy
#15
Chao-Nan Liang, Wei Li, Meng-Jiao Xu, Hai-Feng Ma, Hong-Wen Zhao, Qiu-Yue Wang, Jian Kang, Gang Hou
No abstract text is available yet for this article.
December 1, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/30606328/in-reply
#16
C Hewison, M Bastard, F Varaine, H Huerga
No abstract text is available yet for this article.
December 1, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/30606327/is-6-months-of-bedaquiline-enough
#17
Rony Zachariah, Anthony D Harries, Nimer Ortuno Gutierrez, Piero Olliaro
No abstract text is available yet for this article.
December 1, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/30606326/distinct-functions-of-cxcr3-and-ccr4-cd4-t-cells-accumulated-in-human-tuberculosis-pleural-fluid
#18
S Yu, J Shen, S Lao, B Yang, C Wu
BACKGROUND: Chemokine receptors and their ligands play a prominent role in regulating leucocyte migration. In the local milieu of inflammation, a high concentration of chemokines can recruit different chemokine receptor-expressing lymphocytes. OBJECTIVE: To understand the distinct immunological functions of CXC chemokine receptor 3 (CXCR3+ ) and CC chemokine receptor 4 (CCR4+ ) cluster of differentiation 4 (CD4+ ) T-cells accumulated in human tuberculosis (TB) pleural fluid after tuberculous antigen stimulation...
December 1, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/30606325/high-resolution-melting-curve-analysis-of-heat-shock-protein-65-for-identification-of-mycobacterial-isolates
#19
S Singh, M Sharma, M Modi, A Sharma, R Singh, P Ray, K Sharma
Infections caused by non-tuberculous mycobacteria (NTM) often escape detection on traditional diagnostics. We evaluated the ability of heat shock protein 65 ( hsp 65) polymerase chain reaction and high-resolution melting curve (HRMC) analysis to identify and differentiate Mycobacterium tuberculosis complex (MTC) from NTM in 150 clinical mycobacterial isolates from extra-pulmonary sites. A hundred MTC and 50 NTM isolates were identified. We were able to simultaneously differentiate between seven mycobacterial species using HRMC analysis; a concordance of 100% between hsp 65 HRMC analysis, polymerase chain reaction + restriction analysis and hsp 65 sequencing was observed...
December 1, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/30606324/adverse-reactions-associated-with-long-term-drug-administration-in-mycobacterium-avium-complex-lung-disease
#20
Y Kamii, H Nagai, M Kawashima, M Matsuki, S Nagoshi, A Sato, S Kohno, M Ohgiya, K Ohta
SETTING: The number of patients with non-tuberculous mycobacterial lung disease (NTM-LD) worldwide has been increasing. Mycobacterium avium complex lung disease (MAC-LD) accounts for 90% of NTM-LD. MAC-LD necessitates long-term treatment, but adverse reactions with long-term administration of drugs are poorly understood. OBJECTIVE: To evaluate adverse reactions with long-term administration of drugs for MAC-LD. DESIGN: We conducted a retrospective single-centre medical chart review of 364 patients administered two or more drugs between July 2010 and June 2015...
December 1, 2018: International Journal of Tuberculosis and Lung Disease
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