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Veterinary Journal

T Banzato, G B Cherubini, M Atzori, A Zotti
An established deep neural network (DNN) based on transfer learning and a newly designed DNN were tested to predict the grade of meningiomas from magnetic resonance (MR) images in dogs and to determine the accuracy of classification of using pre- and post-contrast T1-weighted (T1W), and T2-weighted (T2W) MR images. The images were randomly assigned to a training set, a validation set and a test set, comprising 60%, 10% and 30% of images, respectively. The combination of DNN and MR sequence displaying the highest discriminating accuracy was used to develop an image classifier to predict the grading of new cases...
May 2018: Veterinary Journal
F Soutter, S Martorell, L Solano-Gallego, B Catchpole
The clinical outcome of Leishmania infantum infection in dogs varies from subclinical infection to severe disease. Researchers attribute this variability in clinical manifestations to the ability of the immune response to limit pathogen multiplication and dissemination, which is, in part, likely determined by the immune response genes. The aim of this study was to test the hypothesis that MHC class II genes are associated with disease outcome of experimental L. infantum infection in Beagles. Dog leukocyte antigen (DLA) class II haplotypes were characterised by sequence-based typing of Beagle dogs experimentally infected with L...
May 2018: Veterinary Journal
H B Carslake, C McG Argo, G L Pinchbeck, A H A Dugdale, C M McGowan
Reduction of the hyperinsulinaemic response to feeding is central to the management of insulin dysregulation (ID). The aim of this study was to compare insulinaemic and glycaemic responses to soaked hay, dry hay and haylage in ponies. Twelve ponies of mixed breeds were maintained under identical management conditions. A randomised four-way crossover trial was conducted, in which fasted animals were fed a meal of 0.25% body weight as dry matter intake soaked hay, dry hay or haylage, or administered an oral glucose test (OGT)...
May 2018: Veterinary Journal
A Loeffler, D H Lloyd
Canine pyoderma is a common presentation in small animal practice and frequently leads to prescription of systemic antimicrobial agents. A good foundation of knowledge on pyoderma was established during the 1970s and 1980s, when treatment of infection provided relatively few challenges. However, the ability to treat canine pyoderma effectively is now limited substantially by the emergence of multidrug-resistant, methicillin-resistant staphylococci (MRS) and, in some countries, by restrictions on antimicrobial prescribing for pets...
May 2018: Veterinary Journal
C C Rossi, B A B Salgado, E M Barros, P A de Campos Braga, M N Eberlin, W Lilenbaum, M Giambiagi-deMarval
Resistance to mupirocin was analysed in Staphylococcus spp. isolated from healthy dogs (n=21) and dogs with pyoderma (n=47) or otitis externa (n=52). Isolates were identified to species level by MALDI-TOF and PCR-RFLP of the groEL gene. One isolate of Staphylococcus epidermidis from the skin of a healthy dog, which harboured a plasmid carrying the mupA gene, was resistant to mupirocin.
May 2018: Veterinary Journal
L Calzetta, P Roncada, C Piras, A Soggiu, G Liccardi, M Mattei, E Pistocchini
Pets can act as sentinels for human health and thus surveillance of pet dogs has the potential to improve awareness of emerging risks for animal and public health. The aim of this study was to investigate factors associated with the risk of canine poisoning. In a large population-based epidemiological investigation in Italy performed from January 2015 to January 2016 and April 2016 to April 2017, descriptive statistics were acquired and analysed to determine variables associated with poisoning events in pet dogs...
May 2018: Veterinary Journal
Garance Christen, Vinzenz Gerber, Johannes Hermanus van der Kolk, Caroline Franziska Frey, Nathalie Fouché
Pituitary pars intermedia dysfunction (PPID) has been associated with diminished immune response in aged horses. This prospective study hypothesised that this may result in increased strongyle egg shedding in affected animals and that horses treated with pergolide would have reduced fecal egg counts (eggs per gram, EPG) compared to placebo-treated animals. Adrenocorticotropic hormone (ACTH) concentrations and EPG were tested in 48 horses. There were no significant differences in baseline EPG between horses with pre-clinical PPID and healthy controls...
May 2018: Veterinary Journal
S Barbera, M Tarantola, G Sala, C Nebbia
A screening method based on meat quality parameters and production traits for detecting the effects of illegal administration of dexamethasone in Friesian bulls was assessed. Twenty finishing bulls were divided into an untreated control group (n=8) and two treatment groups receiving dexamethasone orally at dosages of 1.4 (n=6) or 0.7 (n=6)mg per head per day for 60 days. The animals were slaughtered 26days after cessation of treatment. Thirty-six parameters were measured on live animals, carcasses and samples of the longissimus thoracis muscle...
May 2018: Veterinary Journal
N Pujato, C M Camussone, M S Renna, M S Perrig, B Morein, L F Calvinho, I S Marcipar
Staphylococcus aureus is a worldwide pathogen that causes mastitis in dairy herds. Shortcomings in control programs have encouraged the development of vaccines against this pathogen. This study evaluated the vaccine candidate VacR, which included recombinant S. aureus protein clumping factor A (rClf), fibronectin binding protein A (rFnBP) and hemolysin beta (rBt), formulated with a novel immune-stimulating complex. Comparisons were made between healthy pregnant heifers that received either VacR (n=8; VacR group) or phosphate buffered saline (PBS) plus adjuvant (control group) SC in the supramammary lymph node area on days 45 and 15 before the expected calving date...
May 2018: Veterinary Journal
N Tamura, K Kodaira, E Yoshihara, N Mae, Y Yamazaki, H Mita, T Kuroda, K Fukuda, A Tomita, Y Kasashima
A retrospective cohort study was conducted to investigate risk factors for the failure of Thoroughbred racehorses to return to racing after an injury of the superficial digital flexor tendon (SDFT). Successful return was defined as the completion of five or more races after SDFT injury. The official Japan Racing Association (JRA) medical records of racehorses with a core-type SDFT injury were reviewed for clinical variables related to the characteristics of the horse and the severity of SDFT injuries at the time of diagnosis...
May 2018: Veterinary Journal
R F Geddes, R E Jepson, Y Forcada, J Elliott, H M Syme
Feline chronic kidney disease (CKD) is associated with high variability in severity of CKD-mineral and bone disorder (CKD-MBD). The calcium sensing receptor (CaSR) regulates circulating parathyroid hormone (PTH) and calcium concentrations. Single nucleotide polymorphisms (SNPs) in the CaSR are associated with severity of secondary renal hyperparathyroidism and total calcium concentrations in human patients receiving haemodialysis. The objective of this study was to explore associations between polymorphisms in the feline CaSR (fCaSR) and biochemical changes observed in CKD-MBD...
May 2018: Veterinary Journal
J L Ireland, C M McGowan
Pituitary pars intermedia dysfunction (PPID) is caused by an age-related degenerative disease of dopaminergic neurones. Despite its importance in equine practice, available information regarding its epidemiology is limited. This systematic review aimed to assess published literature to evaluate available evidence regarding the clinical presentation, prevalence and risk factors for PPID in horses and ponies. Electronic database searches were undertaken using a range of terms, and English language publications published prior to August 2016 were included...
May 2018: Veterinary Journal
P Borusewicz, E Stańczyk, K Kubiak, J Spużak, K Glińska-Suchocka, M Jankowski, J Nicpoń, P Podgórski
Dynamic contrast enhanced (DCE)-magnetic resonance imaging (MRI) consists of acquisition of native baseline images, followed by a series of acquisitions performed during and after administration of a contrast medium. DCE-MRI, in conjunction with hepatobiliary-specific contrast media, such as gadoxetic acid (GD-EOB-DTPA), allows for precise characterisation of the enhancement pattern of the hepatic parenchyma following administration of the contrast agent. The aim of the study was to assess the pattern of temporal resolution contrast enhancement of the hepatic parenchyma following administration of GD-EOB-DTPA and to determine the optimal time window for post-contrast assessment of the liver...
May 2018: Veterinary Journal
T Cachon, O Frykman, J F Innes, B D X Lascelles, M Okumura, P Sousa, F Staffieri, P V Steagall, B Van Ryssen
No abstract text is available yet for this article.
May 2018: Veterinary Journal
E Dijkstra, E Teske, V Szatmári
Respiratory rate is commonly recorded during physical examinations. However, reference intervals are only available for resting and sleeping respiratory rates in cats at home. This observational study aimed to establish reference intervals for the respiratory rate in clinically healthy adult cats at primary-care veterinary clinics. Respiratory rates were recorded from 131 cats, in 6 primary-care veterinary clinics, by observation under four circumstances: by the investigator in the consultation room prior to and during a physical examination, by the owner at home when the cat was resting or sleeping, and by the investigator when watching a video-film of the cat recorded by the owner at home...
April 2018: Veterinary Journal
D A Yang, R A Laven, C Heuer, W D Vink, R N Chesterton
As part of a cross-sectional study of bovine digital dermatitis (BDD) in 60,455 cows across 224 herds, in Taranaki, a region of the North Island of New Zealand, from September 2014 to February 2015, questionnaires from 114 farms were analysed to identify the key management practices which affect the probability of a farm being affected by BDD and the prevalence of an individual cow being affected on affected farms. The data from the questionnaires were analysed using a Bayesian hurdle model. Two factors were identified as being associated with farm level infection status: (1) milking parlour type; farms which had rotary platforms were more likely to be recorded as having BDD than those which had herringbone parlours (odds ratio, OR, 3...
April 2018: Veterinary Journal
L K Harris, H R Whay, J C Murrell
This study investigated the effects of osteoarthritis (OA) on somatosensory processing in dogs using mechanical threshold testing. A pressure algometer was used to measure mechanical thresholds in 27 dogs with presumed hind limb osteoarthritis and 28 healthy dogs. Mechanical thresholds were measured at the stifles, radii and sternum, and were correlated with scores from an owner questionnaire and a clinical checklist, a scoring system that quantified clinical signs of osteoarthritis. The effects of age and bodyweight on mechanical thresholds were also investigated...
April 2018: Veterinary Journal
S L McGowan, S A La Rocca, S S Grierson, A Dastjerdi, B Choudhury, F Steinbach
Schmallenberg virus (SBV) is a vector-borne orthobunyavirus in the family Bunyaviridae, first identified in Germany before rapidly spreading throughout Europe. To investigate the events surrounding the incursion of this virus into Great Britain (GB) and its subsequent spread, archived sheep serum samples from an unrelated field survey in 2011 were analysed for the presence of SBV specific antibodies, to determine the earliest date of seroconversion. This serological study, along with analysis of the spatial spread of the sources of samples submitted for SBV analysis after January 2012, suggests that SBV entered GB on more than one occasion and in more than one location...
April 2018: Veterinary Journal
J M Alonso, R G Peccinini, M L Campos, T Y Nitta, T Y M Akutagawa, A P Crescencio, A L G Alves, C A Rodrigues, M J Watanabe, C A Hussni
Intraperitoneal (IP) use of antimicrobial agents may lead to therapeutic effects with better clinical results than intravenous (IV) administration. The aim of this study was to compare plasma and peritoneal fluid concentrations of ceftriaxone after IP and IV administration in horses, and to evaluate possible adverse effects. One group of five horses received 25mg/kg ceftriaxone diluted in 1L saline solution by IP catheter once daily for 5 days, while a second group of five horses received 25mg/kg ceftriaxone diluted in 250mL saline solution by IV injection once daily for 5days and 1L saline solution by IP catheter once daily for 5 days...
April 2018: Veterinary Journal
R C Anderson, K M Armstrong, W Young, P Maclean, D G Thomas, E N Bermingham
Peripheral blood mononuclear cell (PBMC) gene expression microarray profiling is a minimally invasive tool used in human diet intervention studies. In this study, PBMC gene expression was determined in dogs fed kibble or raw red meat diets for 9 weeks to test the hypothesis that diet influences canine immune cell gene expression profiles. The two diets were associated with differences in PBMC gene expression profiles, which corresponded with changes in plasma IgA concentrations. Analysis of PBMC gene expression profiles might provide useful insights into the long term effects of diet on health outcomes in dogs...
April 2018: Veterinary Journal
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