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Acta Medica (Hradec Králové)

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https://www.readbyqxmd.com/read/30012249/fountain-s-sign-as-a-diagnostic-key-in-acute-idiopathic-scrotal-edema-case-report-and-review-of-the-literature
#1
Dimitrios Patoulias, Vasileios Rafailidis, Thomas Feidantsis, Maria Kalogirou, Dimitrios Rafailidis, Ioannis Patoulias
The acute idiopathic scrotal edema (AISE) is a self-limited disease of unknown etiology, characterized by edema and erythema of the scrotum and the dartos, without expansion to the underlying layers of scrotum's wall or to the endoscrotal structures. Boys younger than 10 years old are usually involved in 60-90% of all cases. Diagnosis is made after exclusion of other causes of acute scrotum. We present a case of a 7-year old boy, who was admitted to the Emergency Department due to development of scrotal edema and erythema over the last 48 hours, which extended to the base of the penis...
2018: Acta Medica (Hradec Králové)
https://www.readbyqxmd.com/read/30012248/a-bilateral-non-syndromic-type-iii-second-branchial-arch-sinus-in-a-neonate-a-case-report
#2
Ioannis Patoulias, Evangelia Rachmani, Konstantinos Farmakis, Vasileios Rafailidis, Maria Kalogirou, Dimitrios Patoulias
The incidence of a second branchial arch sinus accounts for 26-60% of all existing congenital malformations deriving from the branchial apparatus. They are most usually detected between 14 months and 7 years of age, while their incidence during neonatal period and infancy accounts for 0.06% of all cases. The aim of this case study is to emphasize three rare characteristic features: the manifestation during neonatal period, the bilateral localization and the ultrasonographic diagnostic documentation. A 25 days old girl was admitted by her parents due to the presence of mucoid excretion from two small openings found on the neck...
2018: Acta Medica (Hradec Králové)
https://www.readbyqxmd.com/read/30012247/giant-uterine-leiomyoma-in-a-young-woman-as-an-incidental-finding-after-a-car-accident-a-case-report
#3
Vladimír Bartoš, Peter Korec, Robert Ficek
Leiomyomas are the most common benign tumor of the uterus. Occasionally, they may reach an extreme dimension. The authors present a case of a 44-year old woman, who suffered a car accident as a driver of personal motor vehicle. At the hospital, a huge tumor mass filling the entire abdominopelvic cavity was incidentally detected. The patient admitted a progressive abdominal enlargement for the last 5 years. An urgent laparotomy was performed, during which a giant, well-demarcated tumor arising from the uterine body had been disclosed...
2018: Acta Medica (Hradec Králové)
https://www.readbyqxmd.com/read/30012246/modulation-of-rat-liver-regeneration-after-partial-hepatectomy-by-dietary-cholesterol
#4
Pavel Živný, Helena Živná, Vladimír Palička, Lenka Žaloudková, Petra Mocková, Jolana Cermanová, Stanislav Mičuda
INTRODUCTION: The aim of study was to evaluate impact of long-term dietary cholesterol overload on the cholesterol homeostasis and liver regeneration. MATERIAL AND METHODS: Serum lipid parameters, 14C-cholesterol incorporation, liver DNA synthesis and protein expression was determined in partially hepatectomized (PH) rats fed with a standard (SLD) or hypercholesterolemic (CHOL) diet. RESULTS: 29-day intake of CHOL diet before PH produced increase in serum total cholesterol, LDL lipoprotein, and triglyceride concentration...
2018: Acta Medica (Hradec Králové)
https://www.readbyqxmd.com/read/30012245/immunohistochemical-expression-of-cdc7-in-dentigerous-cyst-odontogenic-keratocyst-and-radicular-cyst
#5
Zohreh Jaafari-Ashkavandi, Ahmad Alipour Tuyeh, Sepideh Assar
CDC7 is a serine/threonine kinase which has an essential role in initiation of DNA proliferation and S phase. It increases the invasion and proliferation in many pathologic lesions. This study aimed to evaluate the expression of CDC7 in the most common odontogenic cysts. We evaluated 17 dentigerous cysts, 18 odontogenic keratocysts (OKC) and 13 radicular cysts immunohistochemically. The mean expression of CDC7 was analyzed using ANOVA and Post-HOC methods. All specimens revealed CDC7 expression. Higher expression of CDC7 in OKC and radicular cyst was shown in comparison to dentigerous cyst (P < 0...
2018: Acta Medica (Hradec Králové)
https://www.readbyqxmd.com/read/30012244/exhaled-breath-condensate-pilot-study-of-the-method-and-initial-experience-in-healthy-subjects
#6
Eva Peterová, Jaroslav Chládek, Darina Kohoutová, Veronika Knoblochová, Paula Morávková, Jaroslava Vávrová, Martina Řezáčová, Jan Bureš
Analysis of Exhaled breath condensate (EBC) is a re-discovered approach to monitoring the course of the disease and reduce invasive methods of patient investigation. However, the major disadvantage and shortcoming of the EBC is lack of reliable and reproducible standardization of the method. Despite many articles published on EBC, until now there is no clear consensus on whether the analysis of EBC can provide a clue to diagnosis of the diseases. The purpose of this paper is to investigate our own method, to search for possible standardization and to obtain our own initial experience...
2018: Acta Medica (Hradec Králové)
https://www.readbyqxmd.com/read/30012243/cryopreservation-of-dental-stem-cells
#7
Nela Pilbauerová, Jakub Suchánek
Nowadays, regenerative and reparative medicine has grown in popularity. Dental stem cells are easily accessible source of adult stem cells. They can be harvested by a tooth extraction or spontaneous deciduous tooth exfoliation. They have to be isolated, expanded and stored until time they would be needed for individual stem cell therapy. Cryopreservation is both a short-term and long-term storage of tissues or cells at sub-zero temperatures. There are several methods of cryopreservation requiring different technologies...
2018: Acta Medica (Hradec Králové)
https://www.readbyqxmd.com/read/29716685/sglt-2-inhibitors-are-they-a-promising-treatment-option-in-t2dm-patients-with-nafld
#8
Dimitrios Patoulias
Sodium glucose co-transporter type 2 inhibitors (SGLT-2 inhibitors) are a class of antidiabetics, recently approved for the treatment of patients with T2DM. They feature cardioprotective and renoprotective action, while they exert beneficial effects on metabolic parameters. Non-alcoholic fatty liver disease (NAFLD) is a frequent co-morbidity in diabetic patients. Its prevalence reaches up to 70%. Since there is no specific treatment approved for NAFLD, both experimental and clinical studies have been recently conducted highlighting the efficacy and safety of SGLT-2 inhibitors mainly in animal models and secondarily in patients with T2DM and NAFLD...
2017: Acta Medica (Hradec Králové)
https://www.readbyqxmd.com/read/29716684/giant-metastatic-liver-tumor-of-unknown-primary-origin-thoracic-autopsy-solves-the-mystery
#9
Antigony Mitselou, Stamatis S Papadatos, Savvina Tsoultsidou, Kleio Fragkouli, Michail Mitsis, Theodoros Vougiouklakis, Vasiliki Galani
A 59-year-old male patient was hospitalized in the Internal Medicine Department for investigation of hepatic metastases from an unknown primary neoplasm. During the hospitalization the patient died from acute myocardial infarction. The autopsy revealed a 8.2 kilograms (kg) liver that was diffusely infiltrated by whitish metastatic masses. No other tumor was detected, apart from a 2.5 centimeters (cm) pulmonary nodule next to the right intermediate bronchus that was histologically compatible with small cell lung cancer (SCLC)...
2017: Acta Medica (Hradec Králové)
https://www.readbyqxmd.com/read/29716683/severe-self-inflicted-acute-ocular-siderosis-caused-by-an-iron-tablet-in-the-conjunctival-fornix
#10
Ioannis Asproudis, Paraskevas Zafeiropoulos, Andreas Katsanos, Christos Kolettis
We present the case of a female patient who grinded a ferrous sulfate tablet and placed it at the conjunctival fornix of her left eye. She rapidly developed severe ocular siderosis, with profoundly decreased visual acuity, corneal opacities, cataract, retinal degeneration and ultimately phthisis bulbi. To our knowledge, this is the first report on the consequences of application of an iron tablet on the conjunctiva.
2017: Acta Medica (Hradec Králové)
https://www.readbyqxmd.com/read/29716682/a-large-laryngeal-mucocele-causing-progressive-upper-airway-obstruction-and-cervical-swelling
#11
Ioannis Aidonis, Nikolaos Lazaridis, Maria Piagkou, Nikolaos Anastasopoulos, Konstantinos Natsis
Laryngocele (LC) is an uncommon clinical entity, occasionally associated with fatal complications. If its neck becomes obstructed, mucous accumulates and then a laryngeal mucocele (LMC) is formed. Reports of LMCs are rare in the literature. A fluid-filled combined LMC in a 48 year-old Greek construction worker with presenting symptoms of cervical swelling and dysphonia is described. The male patient was surgically treated via an external approach. A LC rarely becomes symptomatic and infection unusually occurs...
2017: Acta Medica (Hradec Králové)
https://www.readbyqxmd.com/read/29716681/treatment-of-multifocal-multisystem-braf-positive-langerhans-cell-histiocytosis-with-cladribine-surgery-and-allogenic-stem-cell-transplantation
#12
Filip Gabalec, Martin Šimkovič, Alžběta Zavřelová, Petra Kašparová, Paula Morávková, Marcela Kopáčová, Václav Masopust, Pavel Žák, Jan Čáp, Jakub Radocha
Langerhans cell histiocytosis (LCH) is a very rare disease in adults and as well a very rare cause of sellar expansion. The clinical presentation can be heterogeneous, from a single bone lesion to potentially fatal, widespread disease. We describe the difficulties with the diagnosis and treatment of LCH as well as successful treatment with cladribine chemotherapy and allogeneic stem cell transplantation.
2017: Acta Medica (Hradec Králové)
https://www.readbyqxmd.com/read/29716680/prevalence-of-fibromyalgia-syndrome-and-its-correlations-with-arrhythmia-in-patients-with-palpitations
#13
Ayhan Aşkın, Ece Güvendi, Ayten Özkan, Ersin Çağrı Şimşek, Uğur Kocabaş, Aliye Tosun
OBJECTIVE: It is aimed to determine the prevalence of fibromyalgia syndrome (FMS) and its correlations with arrhythmia in patients with palpitations. MATERIAL AND METHODS: Sixty-two patients who underwent electrophysiological study (EPS) due to palpitation complaints in Cardiology department and 40 healthy controls were included in the study. The precise diagnosis of arrhythmia was established using EPS. All participants were screened for FMS using American College of Rheumatology 2010 Fibromyalgia diagnostic criteria...
2017: Acta Medica (Hradec Králové)
https://www.readbyqxmd.com/read/29716679/dose-dependent-prophylactic-efficacy-of-6-chlorotacrine-in-soman-poisoned-mice
#14
Jiří Kassa, Jan Korábečný
AIM: The influence of the dose on the ability of promising newly prepared reversible inhibitor of acetylcholinesterase (6-chlorotacrine) to increase the resistance of mice against soman and the efficacy of antidotal treatment of soman-poisoned mice was evaluated. METHODS: The evaluation of the effect of pharmacological pretreatment is based on the identification of changes of soman-induced toxicity that was evaluated by the assessment of its LD50 value and its 95% confidence limit using probit-logarithmical analysis of death occurring within 24 hrs after administration of soman...
2017: Acta Medica (Hradec Králové)
https://www.readbyqxmd.com/read/29716678/sympathetic-nerve-injury-in-thyroid-cancer
#15
Evangelos Diamantis, Paraskevi Farmaki, Spyridon Savvanis, Georgios Athanasiadis, Theodoros Troupis, Christos Damaskos
The double innervation of the thyroid comes from the sympathetic and parasympathetic nervous system. Injury rates during surgery are at 30% but can be minimized by upwardly preparing the thyroid vessels at the level of thyroid capsule. Several factors have been accused of increasing the risk of injury including age and tumor size. Our aim was to investigate of there is indeed any possible correlations between these factors and a possible increase in injury rates following thyroidectomy. Seven studies were included in the meta-analysis...
2017: Acta Medica (Hradec Králové)
https://www.readbyqxmd.com/read/29439761/amyand-s-hernia-an-up-to-date-review-of-the-literature
#16
REVIEW
Dimitrios Patoulias, Maria Kalogirou, Ioannis Patoulias
Amyand's hernia is defined as an inguinal hernia, containing the appendix within the hernia sac. Incidence of this rare condition rises up to 1% (0.19-1.7%) of all inguinal hernia cases. Inflammation of the appendix within the inguinal sac is even rarer, as it corresponds to 0.1% (0.07-0.13%) of all Amyand's hernia cases. After a comprehensive review of the limited relevant literature, we aim through this review study to describe the pathophysiology of inflammation of the appendix - contained in the hernia sac - and present the latest data about the diagnostic approach and surgical treatment of Amyand's hernia...
2017: Acta Medica (Hradec Králové)
https://www.readbyqxmd.com/read/29439760/rare-abdominal-wall-malformation-case-report-of-umbilical-cord-hernia
#17
Andro Gliha, Andrija Car, Stjepan Višnjić, Bozidar Zupancic, Karmen Kondza, Ivan Petracic
The umbilical cord hernia is the rarest form of abdominal wall malformations, anatomically completely different from gastroschisis and omphalocele. It occurs due to the permanent physiological evisceration of abdominal organs into umbilical celom and persistence of a patent umbilical ring. The umbilical cord hernia is often mistaken for omphalocele and called "small omphalocele". Here we present a case of a female newborn with umbilical cord hernia treated in our Hospital. After preoperative examinations surgery was done on the second day of life...
2017: Acta Medica (Hradec Králové)
https://www.readbyqxmd.com/read/29439759/a-rare-history-an-intracranial-nail-present-for-over-a-half-century
#18
Ozkan Durmaz, Ali Karadag, Fusun Demircivi Ozer, Mahmut Camlar, Erik H Middlebrooks, Baran Bozkurt, Mehmet Senoglu
We present a rare case of a patient with a persistent headache for many years found to have an intracranial nail present for nearly 65 years. The nail was found entering approximately 1 cm from the midline on the left side, passing below the superior sagittal sinus, with the tip 1.5 mm right of the frontal horn of the lateral ventricle. Treatment strategies designed to optimize outcome for intracranial foreign bodies and possible complications are discussed in this report. We also discuss the decision for surgical intervention for foreign bodies and the relevance of position of the foreign body...
2017: Acta Medica (Hradec Králové)
https://www.readbyqxmd.com/read/29439758/bilateral-simultaneous-testicular-torsion-in-a-newborn-report-of-a-case
#19
Zenon Pogorelić, Miro Jukić, Veselin Škrabić, Ivana Mrklić, Vesna Fridl Vidas, Ivo Jurić, Dubravko Furlan
INTRODUCTION: Testicular torsion is a urological emergency. If not recognized in time, this condition may result in ischaemic injury and loss of testis. Simultaneous bilateral neonatal testicular torsion is extremely rare and is usually misdiagnosed. CASE REPORT: We report a case of a male newborn, who presented with bilateral scrotal swelling and redness of the scrotum. Doppler ultrasound supported the diagnosis of bilateral testicular torsion, with an absent blood flow signal on the right side and a weak signal on the left side...
2017: Acta Medica (Hradec Králové)
https://www.readbyqxmd.com/read/29439757/comparative-evaluation-of-effect-of-nano-hydroxyapatite-and-8-arginine-containing-toothpastes-in-managing-dentin-hypersensitivity-double-blind-randomized-clinical-trial
#20
RANDOMIZED CONTROLLED TRIAL
Suresh Anand, Fathima Rejula, Joseph V G Sam, Ramakrishnan Christaline, Mali G Nair, Shiji Dinakaran
PURPOSE: This double blind randomized clinical trial was conducted with the purpose of evaluating the effects of Nano-hydroxyapatite toothpaste as compared to 8% Arginine containing toothpaste in the management of Dentin hypersensitivity (DH). METHOD AND MATERIALS: Patients (30 in each group) suffering from DH and eliciting a VAS score higher than 2 in air blast and tactile test were randomly allocated (block randomization) into either a group 1 (arginine toothpaste) or group 2 (nHA toothpaste)...
2017: Acta Medica (Hradec Králové)
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