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Clinical Journal of Oncology Nursing

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https://www.readbyqxmd.com/read/28738056/advances-in-melanoma-the-rationale-for-the-melanoma-nursing-initiative%C3%A2
#1
Krista M Rubin
This article provides an overview of this supplement, outlining the needs assessment process the Melanoma Nursing Initiative (MNI) used to determine the immunotherapy and targeted therapy topics for discussion as well as the process for developing the consensus statements. The article provides specific discussion of a unique feature of the MNI, the care step pathways (CSPs) for management of adverse events (AEs) associated with melanoma therapies, and looks to the future in terms of the potential benefits of engaging and enabling oncology nurses to adopt a standardized approach to AE management and adherence promotion for melanoma therapies...
August 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28738055/pd-1-inhibitor-therapy-consensus-statement-from-the-faculty-of-the-melanoma-nursing-initiative-on-managing-adverse-events%C3%A2
#2
Suzanne McGettigan, Krista M Rubin
BACKGROUND: Programmed cell death protein 1 (PD-1) inhibitor therapies are now a standard treatment for advanced melanoma and other tumor types. The immune-related adverse events (irAEs) associated with PD-1 inhibitor therapy are drastically different from the AEs associated with chemotherapy. Because these irAEs reflect immune system activation rather than side effects of therapy, nurses should be cognizant of the range of organ systems potentially affected as well as likely clinical presentations...
August 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28738054/ipilimumab-based%C3%A2-therapy-consensus-statement-from-the-faculty-of-the-melanoma-nursing-initiative-on-managing-adverse-events-with-ipilimumab-monotherapy-and-combination-therapy-with-nivolumab
#3
Kathleen M Madden, Brianna Hoffner
BACKGROUND: Ipilimumab (Yervoy®) therapy improves outcomes in patients with resected stage III melanoma, and ipilimumab alone or combined with nivolumab (Opdivo®) does so in those with unresectable or metastatic melanoma. These immunotherapies are associated with immune-related adverse events (irAEs). With prompt recognition and appropriate management, serious sequelae or unnecessary treatment discontinuation can be prevented.
. OBJECTIVES: This article presents consensus statements to guide oncology nurses in the recognition and management of irAEs associated with ipilimumab and nivolumab...
August 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28738053/promoting-oral-therapy-adherence-consensus-statements-from-the-faculty-of-the-melanoma-nursing-initiative-on-oral-melanoma-therapies%C3%A2
#4
Lisa A Kottschade, Mollie Lehner Reed
BACKGROUND: Inhibitors of BRAF and the downstream signaling protein MEK have improved outcomes for patients with BRAF-mutant advanced malignant melanoma. Despite their ease of administration, these oral therapies pose adherence challenges. 
. OBJECTIVES: This article aims to increase awareness of causes of nonadherence to oral targeted therapies in advanced malignant melanoma and to provide oncology nurses with strategies to address these nonadherence issues. 
...
August 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28738052/collaborative-care-in-melanoma-the-essential-role-of-the-nurse%C3%A2
#5
John M Kirkwood, Antoni Ribas
This article provides perspective from medical oncologists on the importance of this supplement from the Melanoma Nursing Initiative. The authors (a) delineate the challenges inherent in addressing adverse event (AE) management with newer melanoma therapies, particularly in the community setting; (b) illustrate how advanced practice providers with extensive clinical trial experience in melanoma are in a key position to set the agenda and educate colleagues on best practices in AE management; and
August 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28738051/braf-mek-%C3%A2-inhibitor-therapy-consensus-statement-from-the-faculty-of-the-melanoma-nursing-initiative-on-managing-adverse-events-and-potential-drug-interactions
#6
Maria Czupryn, Jennifer Cisneros
BACKGROUND: BRAF/MEK inhibitor therapy improves outcomes in BRAF V600E- and V600K-mutated unresectable or metastatic melanoma. However, these regimens are associated with adverse events (AEs) that may lead to unnecessary drug modifications and discontinuations or potentially serious sequelae. In addition, drug-drug interactions (DDIs) may result in AEs or altered therapeutic efficacy.
. OBJECTIVES: This article presents consensus statements to guide nurses in the prevention, recognition, and management of AEs and potential DDIs associated with BRAF/MEK inhibitor therapy...
August 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28738050/intralesional-therapy-consensus-statements-for-best-practices-in-administration-from-the-melanoma-nursing-initiative%C3%A2
#7
Virginia Seery
BACKGROUND: Talimogene laherparepvec (T-VEC) is the first intralesional therapy for melanoma approved by the U.S. Food and Drug Administration. This oncolytic viral immunotherapy has improved outcomes for patients with locoregional recurrent melanoma and is showing promise in combination with systemic therapies. 
. OBJECTIVES: This article aims to provide oncology nurses with expert guidance on best practices in incorporating intralesional therapy for patients diagnosed with melanoma in practice...
August 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28738049/atypical-hemolytic-uremic-syndrome-achieving-positive-patient-outcomes-with-early-diagnosis-and-appropriate-management%C3%A2
#8
Dmitriy Sverdlin, Brenda Peters-Watral
BACKGROUND: Atypical hemolytic uremic syndrome (aHUS), a condition found in adult and pediatric populations, can be idiopathic or acquired as a result of major systemic changes. aHUS presents with a wide array of symptoms that can be attributed to other less dangerous conditions. Because of its complex nature and rare occurrence, it is typically diagnosed in later stages and with multiple organ involvement.
. OBJECTIVES: This article provides an overview of aHUS and available interventions...
August 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28738048/scalp-cooling-the-prevention-of-chemotherapy-induced-alopecia%C3%A2
#9
Anne Katz
Hair loss (alopecia) from chemotherapy is one of the most feared side effects of many patients, particularly women. Many patients and their healthcare providers believe that cryotherapy can help prevent or mitigate these changes. Scalp cooling has been used for more than 30 years to prevent alopecia caused by chemotherapy, particularly taxanes and anthracyclines. This article presents an overview of the evidence for this strategy, as well as its impact on nursing care provision.
August 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28738047/chemomobilization-overview-of-an-educational-quality-improvement-project-for-recipients-of-autologous-stem-cell-transplantation%C3%A2
#10
Zandra R Rivera, Rachelle Nurse, Bryan Fellman, Nicole Brunelle, Kelly J Brassil
BACKGROUND: In preparation for an autologous stem cell transplantation, patients undergo chemomobilization; however, a dearth of standardized, evidence-based patient education on chemomobilization exists in the literature and in practice.
. OBJECTIVES: The purpose of this quality improvement educational initiative is to identify an 
evidence-based approach to appraise the educational needs of patients and their caregivers and to enhance chemomobilization education...
August 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28738046/safety-culture-establishing-processes-to-support-trust-and-accountability-for-risk-reduction-%C3%A2
#11
Tracy Wyant
Oncology nurses are tasked with developing skills that enable vigilant risk surveillance through situational awareness. However, care distractions, task interruptions, increased workloads, and time constraints are common challenges that compete with the ability to provide optimal safe care. A commitment to safety is a professional and organizational expectation, and being empowered to overcome safety-related challenges necessitates multilevel and interprofessional accountability.
.
August 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28738045/camp-raising-spirits-an-oncology-nursing-society-chapter-leadership-success-story%C3%A2
#12
Laura Fennimore, Mary Burgunder, Sandra Lee Schafer, Gayle S Jameson
Oncology Nursing Society (ONS) members share a unique passion for the people they serve and frequently commit to projects that make a difference. Camp Raising Spirits, a weekend retreat for adults with cancer, has made a difference in southwestern Pennsylvania for hundreds of people with cancer and their caregivers for 24 consecutive years. This article will describe how an ONS chapter capitalized on the leadership attributes of partnership, creativity, and commitment to sustain an important community service program...
August 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28738044/survivorship-model-of-care-development-and-implementation-of-a-nurse-practitioner-led-intervention-for-patients-with-breast-cancer%C3%A2
#13
Kathryn E Post, Beverly Moy, Catherine Furlani, Elizabeth Strand, Jane Flanagan, Jeffrey M Peppercorn
BACKGROUND: Despite a call for action to improve survivorship care, no optimal model of care exists. 
. OBJECTIVES: To develop and evaluate the feasibility of a nurse practitioner (NP)-led model of care for survivorship visits after initial therapy. 
. METHODS: Patients received an NP-led survivorship bridge visit (NPSBV) following treatment for early-stage breast cancer. A cross-sectional survey was used to evaluate responses to the NPSBV and patient satisfaction with care...
August 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28738043/the-next-journey-moving-forward-after-cancer-diagnosis-and-treatment%C3%A2
#14
Jane Arboleda, Adrienne Vazquez
Oncology healthcare providers have an obligation to support cancer survivors, not just during active treatment, but also long after they have completed therapy. By providing survivorship care education and establishing programs using evidence-based practice, the specific needs and resources required to aid survivors in this new transition and journey can be identified. Survivors need to be guided, informed, and have their unique needs addressed.
August 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28738042/cognitive-screening-using-the-clock-drawing-test-to-assess-for-preexisting-deficits-in-older-women-diagnosed-with-breast-cancer%C3%A2
#15
Janine Overcash, Maddy Perry
BACKGROUND: Older women diagnosed with breast cancer may also have preexisting cognitive deficits.
. OBJECTIVES: The aim of the current study is to describe errors on the clock-drawing test (CDT), which is used to screen for preexisting cognitive deficits in older women diagnosed with breast cancer.
. METHODS: This descriptive study included a convenience sample of women aged 69 years or older with a diagnosis of breast cancer. The CDT was used to screen for cognitive deficits, such as size of the clock, graphic difficulties, stimulus-bound response, conceptual deficit, spatial and/or planning deficit, and perseveration...
August 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28738041/catheter-associated-urinary-tract-infections-implementing-a-protocol-to-decrease-incidence-in-oncology-populations%C3%A2
#16
Charis McCoy, Monica Paredes, Sara Allen, Jennifer Blackey, Carol Nielsen, Amy Paluzzi, Brittney Jonas, Patti Radovich
BACKGROUND: The impact of catheter-associated urinary tract infections (CAUTIs) on immunocompromised patients with cancer requires preventive intervention from bedside nurses.
. OBJECTIVES: This protocol aims to prevent CAUTIs in the inpatient oncology population by implementing an evidence-based, nurse-driven protocol for discontinuing indwelling urinary catheters (IUCs).
. METHODS: Following a literature review of 34 articles, a nurse-driven CAUTI prevention protocol was developed and implemented on two 26-bed oncology units...
August 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28738040/clinical-nurse-consultant-support-management-of-patients-with-melanoma-receiving-immunotherapy-%C3%A2-and-targeted-therapy%C3%A2
#17
Anna J Lomax, Theresa Nielsen, Lydia Visintin, Brent O'Carrigan, Florian Honeyball, Benjamin Shum, Robyn P M Saw, Catriona McNeil
BACKGROUND: Targeted therapy and immunotherapy agents for advanced melanoma are associated with novel toxicities. Melanoma clinical nurse consultants (CNCs) provide multifaceted clinical care.
. OBJECTIVES: The objective was to evaluate the type of support, excluding clinic and inpatient care, provided by CNCs for patients not enrolled in a clinical trial.
. METHODS: A prospective review of CNC support provided during a 12-week period was conducted...
August 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28738039/chemotherapy-extravasation-establishing-a-national-benchmark-for-incidence-among-cancer-centers
#18
Jeannette Jackson-Rose, Judith Del Monte, Adrienne Groman, Linda S Dial, Leah Atwell, Judy Graham, Rosemary O'Neil Semler, Maryellen O'Sullivan, Lisa Truini-Pittman, Terri A Cunningham, Lisa Roman-Fischetti, Eileen Costantinou, Chris Rimkus, Adrienne J Banavage, Barbara Dietz, Carol J Colussi, Kimberly Catania, Michelle Wasko, Kevin A Schreffler, Colleen West, Mary Lou Siefert, Robert David Rice
BACKGROUND: Given the high-risk nature and nurse sensitivity of chemotherapy infusion and extravasation prevention, as well as the absence of an industry benchmark, a group of nurses studied oncology-specific nursing-sensitive indicators. 
. OBJECTIVES: The purpose was to establish a benchmark for the incidence of chemotherapy extravasation with vesicants, irritants, and irritants with vesicant potential.
. METHODS: Infusions with actual or suspected extravasations of vesicant and irritant chemotherapies were evaluated...
August 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28738038/nurse-education-and-survivorship-building-the-specialty-through-training-and-program-development%C3%A2
#19
Marcia Grant, Mary McCabe, Denice Economou
BACKGROUND: As the number of cancer survivors in the United States continues to grow, the need to educate healthcare providers in the components of survivorship care remains a challenge in the current healthcare system. Survivors have unique concerns and follow-up requirements that are key to minimizing their risks for recurrence and supporting quality of life.
. OBJECTIVES: This article describes the impact of the curriculum, faculty, and teaching methods for an educational program to prepare nurses to provide cancer survivorship care...
August 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28738037/mosaicism-implications-for-genetic-counseling-and-medical-management
#20
Laura Waldman, Suzanne M Mahon
Mosaicism describes the presence of two or more populations of cells with different genotypes in one individual that have developed from a single fertilized egg. This article reviews the various clinical presentations of mosaicism associated with hereditary cancer syndromes and the challenges in providing patients and their families with appropriate genetic testing, as well as provides recommendations for cancer presentation and early detection. Management of mosaicism is based on personal and family history, along with genetic testing results...
August 1, 2017: Clinical Journal of Oncology Nursing
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