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Clinical Journal of Oncology Nursing

Marlon G Saria, Santosh Kesari
BACKGROUND: Glioblastoma (GBM) is a highly aggressive astrocytoma with a dismal prognosis. Since 1976, only three chemotherapeutic agents have been approved for the treatment of GBM. Tumor-treating fields (TTFields) therapy, delivered via a noninvasive device, is a new therapy approved for use in patients with recurrent GBM and in combination with temozolomide for the treatment of newly diagnosed GBM. OBJECTIVES: This article reviews the mechanism of action and findings from preclinical and clinical studies supporting the use of TTFields for patients with newly diagnosed and recurrent GBM...
October 1, 2016: Clinical Journal of Oncology Nursing
Margaret A Schwartz, Lynnette Onuselogu
BACKGROUND: More than 150 years after the first description of glioma cells, patients with glioblastoma (GBM) continue to have a poor prognosis despite standard-of-care therapy. With the introduction of tumor-treating fields (TTFields) therapy for the treatment of recurrent GBM in 2011 and for newly diagnosed GBM in 2015, the opportunity to increase progression-free survival and overall survival while improving quality of life provides a welcome option. OBJECTIVES: This article describes how TTFields therapy may be used in the treatment of patients with recurrent GBM...
October 1, 2016: Clinical Journal of Oncology Nursing
Mary Elizabeth Davis
BACKGROUND: Glioblastoma (GBM) is the most common and aggressive malignant brain tumor in adults. Current treatment options at diagnosis are multimodal and include surgical resection, radiation, and chemotherapy. Significant advances in the understanding of the molecular pathology of GBM and associated cell signaling pathways have opened opportunities for new therapies for recurrent and newly diagnosed disease. Innovative treatments, such as tumor-treating fields (TTFields) and immunotherapy, give hope for enhanced survival...
October 1, 2016: Clinical Journal of Oncology Nursing
Janlyn Murphy, Mary Ellen Bowers, Loretta Barron
BACKGROUND: After receiving U.S. Food and Drug Administration approval for the treatment of newly diagnosed glioblastoma (GBM) in 2015, following initial approval for treatment of recurrent GBM in 2011, Optune®, a device that uses tumor-treating fields (TTFields) therapy, continues to gain acceptance in the practice environment. OBJECTIVES: This article reviews how TTFields differ from traditional GBM treatment approaches and discusses the pivotal role nurses play in helping patients successfully use this therapy...
October 1, 2016: Clinical Journal of Oncology Nursing
Sarah Lindsey, Kim Astroth, Pankaj Kumar
BACKGROUND: Sarcopenic obesity, the dual condition of decreased muscle mass with increased fat mass, can affect morbidity, mortality, and quality of life in adult cancer survivors. OBJECTIVES: The purpose of this project was to determine the effects of the use of an educational toolbox on advanced practice nurses' (APNs') confidence in identifying and managing adult cancer survivors at risk for sarcopenic obesity. METHODS: APNs in an outpatient practice who care for adult cancer survivors received an educational toolbox with strategies to identify and manage adult cancer survivors at risk for sarcopenic obesity...
October 1, 2016: Clinical Journal of Oncology Nursing
Samantha H Weed-Pfaff, Benjamin Nutter, James F Bena, Jennifer Forney, Rosemary Field, Lynn Szoka, Diana Karius, Patti Akins, Christina M Colvin, Nancy M Albert
BACKGROUND: A seven-item cancer-specific fall risk tool (Cleveland Clinic Capone-Albert [CC-CA] Fall Risk Score) was shown to have a strong concordance index for predicting falls; however, validation of the model is needed. OBJECTIVES: The aims of this study were to validate that the CC-CA Fall Risk Score, made up of six factors, predicts falls in patients with cancer and to determine if the CC-CA Fall Risk Score performs better than the Morse Fall Tool. METHODS: Using a prospective, comparative methodology, data were collected from electronic health records of patients hospitalized for cancer care in four hospitals...
October 1, 2016: Clinical Journal of Oncology Nursing
Rhonda L Johnson, Carly Larson, Lora L Black, Kimberly G Doty, Lisa VanHoose
BACKGROUND: The Distress Thermometer (DT) is a well-validated tool that is frequently used in patients with cancer to screen for general distress and to generate referrals. However, a majority of the DT problem list items relate to physical concerns; this may lead to psychosocial issues being overshadowed. OBJECTIVES: The purpose of the current study is to examine the endorsement rates for nonphysical items, as well as the relationship between these items and overall DT scores...
October 1, 2016: Clinical Journal of Oncology Nursing
Fatma Teke, Pakize Bucaktepe, Erkan Kıbrıslı, Melike Demir, Aslıhan Ibiloglu, Ali Inal
BACKGROUND: Patients with brain metastasis (BM) usually suffer from poor quality of life (QOL), anxiety, depression, and sleep disorders in their reduced lifespan. OBJECTIVES: The aim of this study was to evaluate QOL, anxiety, depression, and sleep characteristics in patients with BM at the beginning and end of whole brain radiation therapy (WBRT) and three months after treatment. METHODS: Thirty-three patients undergoing WBRT for BM were featured in this study...
October 1, 2016: Clinical Journal of Oncology Nursing
Denise Menonna-Quinn
The focus of health care has moved toward prevention, and insurance companies are supporting preventive practices that enable their members to remain healthy. Many insurance companies have recorded healthy tips delivered by phone, employed case managers to assist patients in keeping physician appointments, created dedicated hot lines staffed by nurses, and developed resource centers. However, specific instances arise when insurance companies do not allow patients to have certain procedures because of contract language that was previously negotiated between the employer or individual and the insurance company...
October 1, 2016: Clinical Journal of Oncology Nursing
Robin Bavaro-Sakorafos
Surviving cancer was the beginning of a long journey to healing my whole self. When I was first diagnosed with breast cancer, I was 39 years old. I had spent most of my life working in a number of high-stress communications positions in Massachusetts and had recently become the press secretary for Boston's mayor, the Honorable Thomas M. Menino. On day one, I had to tell my new boss that I would need to step down and help him find a replacement because I had cancer. It was an extremely difficult time personally and professionally, but the mayor insisted that I stay...
October 1, 2016: Clinical Journal of Oncology Nursing
Joseph D Tariman, Enisa Mehmeti, Nadia Spawn, Sarah P McCarter, Jessica Bishop-Royse, Ima Garcia, Lisa Hartle, Katharine Szubski
This study aimed to describe the contemporary role of the oncology nurse throughout the entire cancer shared decision-making (SDM) process. Study participants consisted of 30 nurses and nurse practitioners who are actively involved in direct care of patients with cancer in the inpatient or outpatient setting. The major themes that emerged from the content analysis are: oncology nurses have various roles at different time points and settings of cancer SDM processes; patient education, advocacy, and treatment side effects management are among the top nursing roles; oncology nurses value their participation in the cancer SDM process; oncology nurses believe they have a voice, but with various degrees of influence in actual treatment decisions; nurses' level of disease knowledge influences the degree of participation in cancer SDM; and the nursing role during cancer SDM can be complicated and requires flexibility...
October 1, 2016: Clinical Journal of Oncology Nursing
Katelyn Hart, Cindy Tofthagen, Hsiao-Lan Wang
Lung cancer is the second most common cancer; however, it often is not diagnosed until the advanced stages. Early-stage lung cancer is curable, but screening tools are not usually implemented in practice because of a lack of provider awareness. A lung cancer screening decision aid may increase screening use and, ultimately, reduce lung cancer deaths.

October 1, 2016: Clinical Journal of Oncology Nursing
Wendy Pritchett, Karen Kinsley
Fosaprepitant dimeglumine (Emend IV®) is an IV antiemetic that may be beneficial to patients receiving highly emetogenic regimens. Aprepitant (Emend®) is an oral medication that is administered for three consecutive days, whereas fosaprepitant is a single-dose IV medication that is administered on the day of chemotherapy for 20-30 minutes (depending on the IV access type). Fosaprepitant may be useful, yet it can also present a risk for hypersensitivity reactions and phlebitis. Oncology nurses must be aware of the signs and symptoms of these potential adverse events to properly care for their patients...
October 1, 2016: Clinical Journal of Oncology Nursing
Angela K Nooner, Kathleen Dwyer, Lise DeShea, Theresa P Yeo
BACKGROUND: Few studies have been conducted on the use of patient-controlled relaxation and guided imagery interventions for the symptom cluster of pain, fatigue, and sleep disturbance during cancer treatment. OBJECTIVES: The primary aim of this study was to evaluate the feasibility, acceptability, and participant satisfaction with use of patient-controlled relaxation and/or imagery interventions for pain, fatigue, and sleep disturbance. A secondary aim was to examine the data for trends in pain, fatigue, and sleep improvement because of the effects of relaxation and guided imagery...
October 1, 2016: Clinical Journal of Oncology Nursing
Joseph D Tariman, Sadaf Dhorajiwala
BACKGROUND: Cancer-related fatigue (CRF) is the most common stressful side effect caused by cancer and cancer treatments. Although CRF causes a significant burden to quality of life, no pharmacologic interventions are available because the mechanism remains unknown. OBJECTIVES: This systematic review analyzed the genomic variants that have been found to be associated with CRF. METHODS: A search for peer-reviewed articles through PubMed, EBSCOhost, and DePaul WorldCat Libraries Worldwide yielded 16 published studies...
October 1, 2016: Clinical Journal of Oncology Nursing
Martin Wallner, Sabine Köck-Hódi, Shaina Booze, Kathryn J White, Hanna Mayer
BACKGROUND: Personalized targeted therapies have become an emerging paradigm in cancer treatment. Although generally more tolerable than other chemotherapeutic agents, one therapy, epidermal growth factor receptor inhibitors (EGFRIs), commonly results in the formation of cutaneous toxicities, which can negatively affect patients' treatment adherence and quality of life. OBJECTIVES: The aim of this article is to review nursing management strategies for EGFRI-related cutaneous toxicities...
October 1, 2016: Clinical Journal of Oncology Nursing
Lisa M Blackburn, Nicole Bauchmire, Sarah Bender, Kelly Tomlinson-Pinkham, Scott Roberts, Sherry Rosan
BACKGROUND: Acute promyelocytic leukemia (APL), once the most lethal form of adult acute leukemia, has become the most curable. The goal of early and well-managed treatment induction is to reduce the malignant burden of promyelocytes to below the cytologically detectable level. OBJECTIVES: Oncology nurses who care for patients with APL need to be acutely aware of the basic differences in this disease from other forms of leukemia, including the two main complications for the newly diagnosed patient...
October 1, 2016: Clinical Journal of Oncology Nursing
Erica Fischer-Cartlidge, Sonya Romanoff, Bridgette Thom, Chasity Burrows Walters
BACKGROUND: A prospective, quasiexperimental pilot study with a sequential design was performed to compare two methods of teaching self-injection. OBJECTIVES: The study examined 50 patients with breast cancer undergoing adjuvant or neoadjuvant treatment and their caregivers to determine if simulation during the teaching experience affects patient/caregiver satisfaction, worry, and self-confidence, as well as nurse satisfaction. METHODS: Structured questionnaires were administered before the teaching, immediately after the teaching, and after the injection was performed at home...
October 1, 2016: Clinical Journal of Oncology Nursing
Jennifer Bail, Karen Meneses
BACKGROUND: Advancements in chemotherapy have greatly increased breast cancer survival, leading to an increased focus on the management of long-term effects of treatment. Chemotherapy-related cognitive impairment, one such long-term effect, is experienced by as many as 90% of breast cancer survivors (BCS) and negatively affects employment, daily function, and quality of life. Chemotherapy-related cognitive impairment is a top research and clinical practice priority. OBJECTIVES: The aim of this article is to review computer-based cognitive training intervention studies tested in BCS, present implications for practice and directions for future research, and discuss neuroplasticity and cognitive reserve, the mechanisms by which computer-based cognitive training produces physiologic changes in the brain...
October 1, 2016: Clinical Journal of Oncology Nursing
Karlen E Luthy, Sarah L Stocksdale, Janelle L B Macintosh, Lacey M Eden, Renea L Beckstrand, Katie Edmonds
BACKGROUND: All major hospital facilities in the state of Utah have employee vaccination policies. However, the presence of healthcare worker vaccination policies in outpatient oncology clinics was unknown. OBJECTIVES: The objectives of this article are to identify oncology outpatient employee vaccination policies in Utah and to identify what consequences, if any, are present for unvaccinated employees. METHODS: This was a cross-sectional, descriptive study design in which clinic managers from outpatient oncology clinics were asked, via questionnaire, to describe the clinic's employee vaccination policy and the consequences for refusing the policy...
October 1, 2016: Clinical Journal of Oncology Nursing
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