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Journal of Lower Genital Tract Disease

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https://www.readbyqxmd.com/read/28263237/international-image-concordance-study-to-compare-a-point-of-care-tampon-colposcope-with-a-standard-of-care-colposcope
#1
Jenna L Mueller, Elizabeth Asma, Christopher T Lam, Marlee S Krieger, Jennifer E Gallagher, Alaattin Erkanli, Roopa Hariprasad, J S Malliga, Lisa C Muasher, Bariki Mchome, Olola Oneko, Peyton Taylor, Gino Venegas, Anthony Wanyoro, Ravi Mehrotra, John W Schmitt, Nimmi Ramanujam
OBJECTIVE: Barriers to cervical cancer screening in low-resource settings include lack of accessible, high-quality services, high cost, and the need for multiple visits. To address these challenges, we developed a low-cost, intravaginal, optical cervical imaging device, the point-of-care tampon (POCkeT) colposcope and evaluated whether its performance is comparable with a standard-of-care colposcope. MATERIALS AND METHODS: There were 2 protocols, which included 44 and 18 patients...
March 3, 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/28257290/human-papillomavirus-co-testing-results-effectively-triage-normal-cervical-cytology-in-hiv-positive-women-aged-30-years-and-older
#2
Rachel O Alade, Olivera Vragovic, Conor Duffy, Howard J Cabral, Elizabeth A Stier
OBJECTIVE: The aim of the study was to assess whether HIV-positive (HIV+) women aged 30 years and older with concurrent normal cervical cytology and undetectable cervical HPV have a low 3-year risk of developing cervical intraepithelial neoplasia grade 2 or higher (CIN 2+) in a clinical setting. MATERIALS AND METHODS: We conducted a retrospective chart review of HIV+ women aged 30 years and older at a single institution with normal cervical cytology and concurrent human papillomavirus (HPV) testing between November 2008 and December 2010...
March 2, 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/28244885/preparing-for-the-next-round-of-asccp-sponsored-cervical-screening-and-management-guidelines
#3
Mark Schiffman, Nicolas Wentzensen, Michelle J Khan, Philip E Castle, David Chelmow, Warner K Huh, Anna Barbara Moscicki, Colleen K Stockdale, Teresa M Darragh, Michelle Silver, Richard S Guido
No abstract text is available yet for this article.
February 27, 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/28244884/triaging-atypical-squamous-cells-cannot-exclude-high-grade-squamous-intraepithelial-lesion-with-p16-ki67-dual-stain
#4
Daja Šekoranja, Alenka Repše Fokter
OBJECTIVES: The management of women with Pap cytology results categorized as "atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion" (ASC-H) can often be challenging. We assessed the performance of p16/Ki67 dual-stained cytology as a potential triage tool for the detection of biopsy-confirmed high-grade squamous intraepithelial lesions (HSILs) in women with ASC-H. MATERIALS AND METHODS: Women with ASC-H were followed for a period of 36 months by repeat cytology and colposcopy...
February 27, 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/28166106/lymphoma-presenting-as-a-mass-of-the-vulva-report-of-a-case-of-a-rare-vulvar-neoplasm-not-treated-by-surgery
#5
Qing Wang, Bernadette Cracchiolo, Debra S Heller
No abstract text is available yet for this article.
February 3, 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/28157827/vulvar-adenocarcinoma-with-neuroendocrine-differentiation-a-case-report
#6
Sofia Gabrilovich, Bernadette Cracchiolo, Debra S Heller
No abstract text is available yet for this article.
February 3, 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/28157826/impact-of-age-at-conization-on-obstetrical-outcome-a-case-control-study
#7
Julien Chevreau, Antonin Mercuzot, Arthur Foulon, Chirstophe Attencourt, Fabrice Sergent, Ségolène Lanta, Jean Gondry
OBJECTIVE: The aim of the study was to assess whether an age younger than 25 years at conization affected future pregnancy outcome as an independent factor. MATERIALS AND METHODS: A retrospective study of 115 women who underwent both loop electrosurgical excision procedure (LEEP) and subsequent pregnancy follow-up in a referral center was conducted. Two groups were considered: patients younger than 25 years at the time of LEEP (n = 42) and 25 years or older (n = 73)...
February 3, 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/28157825/pain-sensation-during-colposcopy-and-cervical-biopsy-with-or-without-local-anesthesia-a-randomized-trial
#8
Mari Kiviharju, Ilkka Kalliala, Pekka Nieminen, Tadeusz Dyba, Annika Riska, Maija Jakobsson
OBJECTIVE: The aim of the study was to determine whether an injection of a local anesthetic is more painful than a cervical punch biopsy without local anesthesia. MATERIALS AND METHODS: The study was a randomized controlled trial, conducted at the Helsinki University Central Hospital. It consisted of 204 women referred for colposcopic assessments. Half of them were randomized to receive local anesthesia before their cervical punch biopsies. After the injection of the local anesthetic, the cervical punch biopsy, and the endocervical curettage, the women scored their actual pain using a 10-cm visual analog scale (VAS)...
February 3, 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/28157824/label-free-imaging-of-female-genital-tract-melanocytic-lesions-with-pump-probe-microscopy-a-promising-diagnostic-tool
#9
Francisco E Robles, Sanghamitra Deb, Martin C Fischer, Warren S Warren, Maria Angelica Selim
OBJECTIVES: Melanomas of the female genital tract present a unique clinical challenge. Not only are these lesions in an anatomically sensitive area, but also they tend to be multifocal and have high recurrence rates. Furthermore, several benign melanocytic proliferations resemble early-stage melanoma clinically and/or histopathologically. Thus, there is a significant need for additional tools that can help correctly diagnose and stage these lesions. Here, we quantitatively and nondestructively analyze the chemical composition of melanin in excised pigmented lesions of the female genital tract using pump-probe microscopy, a high-resolution optical imaging technique that is sensitive to many biochemical properties of melanin...
February 3, 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/28157823/speculum-lubrication
#10
Beuy Joob, Viroj Wiwanitkit
No abstract text is available yet for this article.
February 3, 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/28323745/conflict-of-interest-disclosures
#11
(no author information available yet)
No abstract text is available yet for this article.
April 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/28027122/genitogluteal-porokeratosis-in-a-well-woman
#12
Tracy Kristine Foran, Tania Day, Jennifer Bradford, James Scurry
No abstract text is available yet for this article.
January 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/28027121/carcinogenesis-of-vulvar-lesions-morphology-and-immunohistochemistry-evaluation
#13
Raquel Camara Rivero, Deborah Garcia, Luciano Serpa Hammes, Marcelle Reesink Cerski, Valentino Magno, Lúcia Maria Kliemann, Edison Capp
OBJECTIVES: The aim of the study was to assess the 2 pathways of vulvar carcinogenesis and correlate immunohistochemical expression of p53 with histopathological findings. MATERIALS AND METHODS: This cross-sectional study included 76 cases. Patients were classified according to the 2004 International Society for the Study of Vulvovaginal Disease Terminology, followed by a review of clinical records and immunohistochemical staining for p53. RESULTS: Fifteen cases were in the human papillomavirus (HPV)-associated pathway (12 cases of usual vulvar intraepithelial neoplasia [VIN] and 3 of warty squamous cell carcinoma [SCC]), and 13 cases were in the HPV-independent pathway (5 cases of differentiated VIN and 8 of keratinizing SCC)...
January 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/28027120/cervical-cancer-screening-of-adolescents-should-not-be-encouraged
#14
Laílca Quirino Henrique, Adriana Bittencourt Campaner, Flavia Salomão dʼAvila
OBJECTIVE: The study aims to assess the frequency of cytological abnormalities in adolescents and young women, to establish the optimum age to start screening. METHODS: A retrospective study of cervical cytology results were obtained from the data center at the Santa Casa Hospital of São Paulo between January 2006 and December 2014, adopting the Bethesda nomenclature system. The cytology exams were divided into 3 groups: group 1-adolescents (10-19 years old); group 2-young women (20-24 years old); and group 3-adults, comprising the remaining cytology exams...
January 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/27922905/scale-up-of-an-human-papillomavirus-testing-implementation-program-in-el-salvador
#15
Miriam Cremer, Mauricio Maza, Karla Alfaro, Mario Morales Velado, Juan Felix, Philip E Castle, Jane Kim, Julia C Gage
OBJECTIVE: The Cervical Cancer Prevention in El Salvador is a demonstration project to introduce a lower-cost human papillomavirus (HPV)-DNA test into a public sector project. Started in October 2012, The Cervical Cancer Prevention in El Salvador consists of 3 phases and will ultimately screen 30,000 women. Results of phase 2 of the project are presented. The objective of this project was to compare colposcopy and noncolposcopy-based management for HPV-positive women. MATERIAL AND METHODS: In phase 2, a total of 8,050 women, aged 30 to 49 years, were screened; 6,761 provided both self- and provider-collected specimens and 1,289 provided only provider-testing specimens...
January 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/27906806/awareness-of-cervical-cancer-causes-and-predeterminants-of-likelihood-to-screen-among-women-in-haiti
#16
Schatzi H McCarthy, Kathy A Walmer, Joel C Boggan, Margaret W Gichane, William A Calo, Harry A Beauvais, Noel T Brewer
OBJECTIVES: Cervical cancer is the leading cause of cancer deaths among women in Haiti. Given this high disease burden, we sought to better understand women's knowledge of its causes and the sociodemographic and health correlates of cervical cancer screening. MATERIALS AND METHODS: Participants were 410 adult women presenting at clinics in Léogâne and Port-au-Prince, Haiti. We used bivariate and multivariate logic regression to identify correlates of Pap smear receipt...
January 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/27906805/predictors-of-positive-margins-at-time-of-loop-electrosurgical-excision-procedure
#17
Jill Liss, Meredith Alston, Mona B Krull, Sara E Mazzoni
OBJECTIVE: The aim of the study was to identify factors associated with the presence of high-grade squamous intraepithelial lesion (HSIL) at surgical margins of loop electrosurgical excision procedure (LEEP) pathology specimens. MATERIALS AND METHODS: All women evaluated for lower genital tract disease at a single academic institution were prospectively entered into a database. The database was queried for all women who had a LEEP performed for indications within contemporary American Society of Colposcopy and Cervical Pathology guidelines between April 1, 2013, and April 30, 2015...
January 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/27851696/a-comparison-of-the-strength-of-association-of-reid-colposcopic-index-and-swede-score-with-cervical-histology
#18
COMPARATIVE STUDY
Renu Ranga, Shweta Rai, Aruna Kumari, Sandeep Mathur, Alka Kriplani, Reeta Mahey, Nutan Agarwal, Garima Kachhawa, Perumal Vanamail, Neerja Bhatla
OBJECTIVE: Colposcopic scoring systems provide an objective diagnosis and select patients who require treatment. A new scoring system, Swede score, has added lesion size as a parameter. This study aimed to compare the strength of association of Reid colposcopic index versus Swede score and assess their utility in low-resource settings. METHODS: In this prospective study, 150 women aged 30 to 59 years with abnormal screening result were enrolled. All women underwent colposcopy; the findings were scored by both Reid colposcopic index and Swede score, biopsy taken from all abnormal areas...
January 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/27851695/evaluation-of-viral-load-as-a-triage-strategy-with-primary-high-risk-human-papillomavirus-cervical-cancer-screening
#19
Hongxue Luo, Jerome L Belinson, Hui Du, Zhihong Liu, Lijie Zhang, Chun Wang, Xinfeng Qu, Robert G Pretorius, Ruifang Wu
OBJECTIVE: The aim of the study was to evaluate the human papillomavirus (HPV) viral load combined with cytology as a secondary screening strategy after primary HPV screening. MATERIALS AND METHODS: The data referring to direct Hybrid Capture 2 (HC2), cytology, and histology from Shenzhen Cervical Cancer Screening Trial II were re-analyzed to determine the correlation between viral load and cervical lesions. In addition, algorithms using different viral loads as cut points for immediate colposcopy plus cytology triage were compared with several recommended or controversial primary screening methods...
January 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/27824789/predictors-of-persistent-or-recurrent-disease-after-loop-electrosurgical-excision-procedure
#20
Helen E Cejtin, Lindsay Zimmerman, Melissa Mathews, Ashlesha Patel
OBJECTIVE: Follow-up recommendations after an excisional procedure vary depending on whether or not there is a positive ectocervical or endocervical margin or endocervical curettage (ECC). The purpose of this study was to evaluate the importance of these findings in predicting recurrent/persistent (r/p) disease in a sample of human immunodeficiency virus (HIV)-seropositive and -negative patients. MATERIALS AND METHODS: Loop electrosurgical excision procedures with a concurrent ECC performed at the Cook County ambulatory clinic between September 29, 2008, and April 15, 2014 were included in this study...
January 2017: Journal of Lower Genital Tract Disease
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