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Journal of Lower Genital Tract Disease

Jhalak Dholakia, Deborah Bartholomew
No abstract text is available yet for this article.
October 1, 2018: Journal of Lower Genital Tract Disease
Munetoshi Akazawa, Toshiaki Saito, Masao Okadome, Kazuya Ariyoshi
OBJECTIVE: The aim of this study was to compare the outcomes associated with the use of a novel monopolar scalpel with those associated with the use of an ultrasonic scalpel for cervical conization of cervical intraepithelial neoplasia. MATERIALS AND METHODS: We conducted a retrospective cross-sectional study in patients treated in our institute between April 2010 and March 2017. We used either the VIO monopolar scalpel (VIO) or Harmonic ultrasonic scalpel (HS) for cervical conization...
September 26, 2018: Journal of Lower Genital Tract Disease
Panteha Eshtiaghi, Leslie Ann Sadownik
OBJECTIVE: The aim of the study was to summarize and review the evidence for the efficacy and safety of adipose-derived stem cells (ADSCs) and platelet-rich plasma (PRP) for the treatment of vulvar lichen sclerosus (LS). MATERIALS AND METHODS: PubMed/MEDLINE, Ovid, Web of Science, and were searched from inception up to May 7, 2018. RESULTS: Seven observational studies were identified, with a total of 98 patients. Both ADSCs and PRP were reported to improve symptoms, quality of life measures, as well as clinical and histological signs of vulvar LS...
September 24, 2018: Journal of Lower Genital Tract Disease
Cathrin Alvendal, Witchuda Kamolvit, Siegfried Wagner, Annelie Brauner, Nina Bohm-Starke
OBJECTIVES: Persistent infection with human papillomavirus causes cervical high-grade squamous intraepithelial lesions (HSILs). The role of antimicrobial peptides (AMPs) in premalignant and malignant transformation is not fully understood. In this study, we examined the expression of human β-defensin 1 (HBD-1), HBD-2, HBD-3, LL37, psoriasin, and interleukin 8 (IL-8) in women with HSIL before and 6 months after surgery. MATERIALS AND METHODS: Biopsies and secretion samples from the cervical canal were collected from 19 patients with HSIL and 14 healthy controls...
September 20, 2018: Journal of Lower Genital Tract Disease
Melissa Bradbury, Natalia Xercavins, Ángel García-Jiménez, Asunción Pérez-Benavente, Silvia Franco-Camps, Silvia Cabrera, José Luis Sánchez-Iglesias, Javier De La Torre, Berta Díaz-Feijoo, Antonio Gil-Moreno, Cristina Centeno-Mediavilla
OBJECTIVES: The data available on vaginal intraepithelial neoplasia (VAIN) and infection by HIV are scarce. We therefore aimed to review the clinical presentation, management, and survival outcomes of VAIN in this group of women. MATERIALS AND METHODS: This is an observational cohort study of women diagnosed with VAIN for a 23-year period. Clinical characteristics and outcomes were analyzed according to women's HIV infection status. Disease-free and progression-free survival were compared between groups...
August 29, 2018: Journal of Lower Genital Tract Disease
Yun Liang, Bingjian Lü, Caiyun Zhou
OBJECTIVE: The aims of this study were to clarify the histological features of adenoid basal carcinoma (ABC) and determine whether cytokeratin 17 (CK17) and Ki-67 can facilitate the differential diagnosis of ABC from squamous cell carcinoma (SCC). MATERIALS AND METHODS: Nine cases of pure ABC were collected from the files of the Division of Pathology at the Zhejiang University Hospital Women's School of Medicine. For comparison, 20 cases of moderately to poorly differentiated cervical SCC, including 2 of basaloid SCC, were also retrieved from the same period...
August 13, 2018: Journal of Lower Genital Tract Disease
Emilie Demarquet, Julien Mancini, Lise Preaubert, Jean Gondry, Julien Chevreau, Gery Lamblin, Karine Lebail, Vincent Lavoué, Marion Pinsard, Jean-Jacques Baldauf, Angélique Bryand, Sebastien Henno, Aubert Agostini, Serge Douvier, Adelaïde Jarniat, Didier Riethmuller, Anne Mendel, Jean-Luc Brun, Hajanirina Rakotomahenina, Xavier Carcopino
OBJECTIVE: The aim of the study was to identify the risk factors of post-large loop excision of the transformation zone (LLETZ) recurrent disease and the impact of colposcopic guidance at the time of LLETZ on that risk. MATERIALS AND METHODS: From December 2013 to July 2014, 204 patients who had undergone LLETZ for the treatment of high-grade intraepithelial lesion with fully visible cervical squamocolumnar junction were included. The use of colposcopy during each procedure was systematically documented...
August 6, 2018: Journal of Lower Genital Tract Disease
Mark B Woodland, Laura Callanan, Peter F Schnatz, Xuezhi Jiang
OBJECTIVE: The aim of the study was to promote the importance of providing gynecologic screening for transgender men (TGM) who desire to keep their female organs. MATERIALS AND METHODS: In June 2015, the Women's Health Center (WHC) at Reading Hospital was approached to become a resource for transgender (TG) patients in our community. This also presented the opportunity to develop an educational program for OBGYN residents/providers in TG healthcare. From June 2015 to August 2016, we educated ourselves, established standards of care, collaborated with other services, and reached out to the community we represent...
October 2018: Journal of Lower Genital Tract Disease
Molly Lieber, Christopher W Reynolds, Whitney Lieb, Stephen McGill, Ann Marie Beddoe
OBJECTIVE: The aim of this study was to assess human papillomavirus (HPV) prevalence, knowledge, attitudes, and practices, among men who have sex with men (MSM) in Monrovia, Liberia. MATERIALS AND METHOD: This cross-sectional study was conducted with 107 MSM, aged 18 to 58 years, completing questionnaires and anal HPV screenings. Using peer-educators and direct community involvement, demographics, risk factors, and HPV knowledge data were collected. RESULTS: Forty-eight participants (45%) were HPV positive and 21 participants (19...
October 2018: Journal of Lower Genital Tract Disease
Sarah Feldman, Erin Cook, Michelle Davis, Susan T Gershman, Amresh Hanchate, Jennifer S Haas, Rebecca B Perkins
IMPORTANCE: Current cancer screening guidelines recommend cessation of cervical cancer screening at the age of 65 years for most women. To examine residual risk among elderly women, we compared cervical cancer incidence rates (IRs) in Massachusetts from 2004 to 2015 among women younger than 65 years versus 65 years and older. MATERIALS AND METHODS: The Massachusetts Cancer Registry was used to identify all women diagnosed with cervical cancer between January 01, 2004, to December 31, 2015...
October 2018: Journal of Lower Genital Tract Disease
Cortney Eakin, Rodrigue Ekollo, Derick Nembulefack, Gregory Halle-Ekane, Gracious Tangui, Robert Brady, Bikash Bhattarai, George Enow Orock, David Greenspan
OBJECTIVE: The aim of the study was to determine beliefs and utilization of cervical cancer screening and prevalence of low-grade squamous intraepithelial lesion/high-grade squamous intraepithelial lesion among a university-based population in the Southwest region of Cameroon. MATERIALS AND METHODS: A public-private partnership was established between the University of Arizona, University of Buea, and the Cameroon Baptist Convention Health Services. A single-day screening clinic using visual inspection with acetic acid and Lugol's iodine solution (VILI) was provided at the University of Buea...
October 2018: Journal of Lower Genital Tract Disease
Kimberly A Kilfoyle, Andrea C Des Marais, Mai Anh Ngo, LaHoma Romocki, Alice R Richman, Lynn Barclay, Noel T Brewer, Lisa Rahangdale, Jennifer S Smith
OBJECTIVES: Self-collection of samples for human papillomavirus (HPV) testing (self-collection) has the potential to increase cervical cancer screening among underscreened women. We assessed attitudes toward at-home HPV self-collection compared with clinic-based Pap testing in this higher-risk population. MATERIALS AND METHODS: Participants were low-income women in North Carolina overdue for cervical cancer screening. Women self-collected samples at home, returned samples by mail for HPV testing, and completed phone questionnaires about at-home HPV self-collection...
October 2018: Journal of Lower Genital Tract Disease
Amelia B Thompson, Scott E Gillespie, Marina B Mosunjac, Sophia A Hussen, Lisa C Flowers, Andres F Camacho-Gonzalez
OBJECTIVE: Anal cancer rates are increasing among HIV-infected persons. Although an efficacious human papillomavirus (HPV) vaccine is available, HPV vaccination rates remain low. Therefore, providers perform anal cancer screening, but there is no consensus on the optimal methods or timing of screening. This study was performed to determine the prevalence of and factors associated with anal squamous intraepithelial lesions in sexually active HIV-infected young men who have sex with men and transgender women...
October 2018: Journal of Lower Genital Tract Disease
Anna-Barbara Moscicki, Rebecca B Perkins, Marion Saville, Julia M L Brotherton
No abstract text is available yet for this article.
October 2018: Journal of Lower Genital Tract Disease
Anh Q Nguyen, Morgan Mandigo, Jenell S Coleman
Women with disabilities are underscreened for cervical cancer compared with the general population, likely because, in part, of both emotional and physical challenges associated with Pap testing. Women with certain disabilities often require an examination under anesthesia to undergo a speculum examination. However, anesthesia is not without risks and the perioperative experience can be burdensome to patients and caregivers. Either self-collected or provider-collected samples for human papillomavirus (HPV) testing might be better tolerated by patients, and recent evidence suggests that it is a suitable primary screening strategy...
October 2018: Journal of Lower Genital Tract Disease
Jennifer C Molokwu, Eribeth Penaranda, Alok Dwivedi, Indika Mallawaarachchi, Navkiran Shokar
OBJECTIVE: The aims of the study were to evaluate the effect of a community outreach worker (promotora)-led high-intensity educational intervention compared with control without promotora-led intervention on cervical cancer screening preference (Pap smear vs self-sampling) and to determine the effect of this preference on subsequent screening completion. MATERIALS AND METHODS: This randomized controlled trial compared the effect of educational intervention on women's preferences for self-sampling for human papillomavirus...
October 2018: Journal of Lower Genital Tract Disease
Anastasios Tranoulis, Dimitra Georgiou, Alexandros Laios, Georgios Theophilou, Amudha Thangavelu, Richard Chanellor Hutson
OBJECTIVE: In the absence of standard guidelines, the management of vaginal intraepithelial neoplasia (VaIN) remains a field of debate. The aim of this systematic review and meta-analysis was to ascertain the 5-flouorouracil (5-FU) effectiveness in this context. MATERIALS AND METHODS: A literature search was conducted throughout the PubMed, EMBASE, SCOPUS,, and Cochrane Databases for relevant studies. We computed the summary proportions of women treated for VaIN with 5-FU for the outcomes of complete response and recurrence by random-effects meta-analysis...
October 2018: Journal of Lower Genital Tract Disease
Ali E McGregor, Kimberly Gecsi
OBJECTIVE: The aim of the study was to determine whether treating all patients older than 25 years with high-grade squamous intraepithelial lesion (HSIL) Paps with immediate loop electrode excisional procedure (LEEP) improves rates of receiving indicated treatment and evaluating whether this practice results in overtreatment (defined by excisional pathology less than cervical intraepithelial neoplasia 2). MATERIALS AND METHODS: This was a retrospective cohort study at an urban, Medicaid-based clinic, which evaluated women older than 25 years with HSIL Pap results seen from June 2011 to December 2016...
October 2018: Journal of Lower Genital Tract Disease
Herschel W Lawson, Mona Saraiya
No abstract text is available yet for this article.
October 2018: Journal of Lower Genital Tract Disease
Amy L Stenson, Catherine Leclair
Periclitoral masses are uncommon disorders in gynecology often leading to pain and distress. With the popularity of female genital hair grooming and depilation, the vulva has been exposed to new insults including contact dermatitis and folliculitis. The unique anatomy of the protective covering of the clitoral hood may subject hair fragments to trapping, inflammation, irritation, and in some cases abscess formation.
October 2018: Journal of Lower Genital Tract Disease
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