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Journal of Lower Genital Tract Disease

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https://www.readbyqxmd.com/read/29794821/in-defense-of-a-simplified-practical-colposcopic-terminology
#1
Michelle J Khan, L Stewart Massad, Warner K Huh, Nicolas Wentzensen
No abstract text is available yet for this article.
May 23, 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29794532/equal-management-of-equal-risks-what-should-be-used-as-the-standard-for-cervical-cancer-prevention
#2
Walter K Kinney, Rebecca B Perkins, George F Sawaya
No abstract text is available yet for this article.
May 22, 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29762429/the-results-of-an-italian-quality-assurance-program-support-the-new-american-society-for-colposcopy-and-cervical-pathology-recommendations-for-colposcopy-practice
#3
Paola Garutti, Paolo Cristiani, Stefano Ferretti, Priscilla Sassoli de Bianchi, Alessandra Ravaioli, Lauro Bucchi
No abstract text is available yet for this article.
May 14, 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29762430/the-impact-of-varying-numbers-of-quadrivalent-human-papillomavirus-vaccine-doses-on-anogenital-warts-in-the-united-states-a-database-study
#4
Burak Zeybek, Yu-Li Lin, Yong-Fang Kuo, Ana M Rodriguez
OBJECTIVE: The aim of the study was to investigate the effects of 3 or less quadrivalent human papillomavirus (HPV) vaccine doses on anogenital warts in both males and females in the United States. MATERIALS AND METHODS: We conducted a retrospective database study that included males and females aged 9 to 26 years who received varying numbers of vaccine doses between 2006 and 2015. The primary outcome was the incidence of anogenital warts starting 3 months after the last dose of the HPV vaccine...
May 8, 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29762428/outcomes-of-conservative-management-of-high-grade-squamous-intraepithelial-lesions-in-young-women
#5
Marette H Lee, Sarah J Finlayson, Ksenia Gukova, Gillian Hanley, Dianne Miller, Leslie Ann Sadownik
OBJECTIVE: The aim of the study was to determine regression rates of cervical intraepithelial neoplasia (CIN) 2 and 3 in women younger than 24 years, followed conservatively for up to 24 months. MATERIALS AND METHODS: This is a retrospective chart review of colposcopy patients in clinic database based on the following: (1) younger than 24 years at first visit; (2) first visit January 1, 2010, to May 31, 2013, and at least 1 follow-up visit after diagnosis; (3) histologic diagnosis of CIN2+; and (4) optimal conservative management (observation for up to 24 months or to 24 years, whichever occurred first)...
May 4, 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29733302/excess-cost-of-cervical-cancer-screening-beyond-recommended-screening-ages-or-after-hysterectomy-in-a-single-institution
#6
Deanna Teoh, Gretchen Hultman, McKenzie DeKam, Rachel Isaksson Vogel, Levi S Downs, Melissa A Geller, Chap Le, Genevieve Melton, Shalini Kulasingam
OBJECTIVE: The aim of the study was to estimate the excess cost of guideline nonadherent cervical cancer screening in women beyond the recommended screening ages or posthysterectomy in a single healthcare system. MATERIALS AND METHODS: All Pap tests performed between September 1, 2012, and August 31, 2014, in women younger than 21 years, older than 65 years, or after hysterectomy, were coded as guideline adherent or nonadherent per the 2012 America Society of Colposcopy and Clinical Pathology guidelines...
May 3, 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29672447/effects-of-human-papillomavirus-awareness-and-knowledge-on-psychological-state-of-women-referred-to-cervical-cancer-screening
#7
Ljiljana Markovic-Denic, Olivera Djuric, Natasa Maksimovic, Svetlana Popovac, Vesna Kesic
OBJECTIVE: The aim of the study was to assess the impact of human papillomavirus (HPV) awareness and knowledge on physiological state and quality of life of women referred to colposcopy and/or HPV testing. MATERIALS AND METHODS: A cross-sectional study was carried out at University Hospital, Belgrade, Serbia. The women with abnormal Pap test results obtained at the primary care centers requiring colposcopy and/or HPV testing were included. Before gynecological examination, participants filled the questionnaire on demographic characteristics, gynecological history, questionnaire for the evaluation of HPV awareness and HPV knowledge level, a set of self-report questionnaires assessing the anxiety level, quality of life, and concern about the smear and colposcopy results and perceived risk of developing cervical cancer...
April 19, 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29649025/risk-of-anal-cancer-in-women-with-a-human-papillomavirus-related-gynecological-neoplasm-puerto-rico-1987-2013
#8
Adrianna I Acevedo-Fontánez, Erick Suárez, Carlos R Torres Cintrón, Ana P Ortiz
OBJECTIVE: The aim of the study was to estimate the magnitude of the association between HPV-related gynecological neoplasms and secondary anal cancer among women in Puerto Rico (PR). MATERIALS AND METHODS: We identified 9,489 women who had been diagnosed with a primary cervical, vaginal, or vulvar tumor during 1987-2013. To describe the trends of invasive cervical, vulvar, vaginal, and anal cancer, the age-adjusted incidence rates were estimated using the direct method (2000 US as Standard Population)...
April 11, 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29601402/risk-factors-for-anal-dysplasia-in-transgender-women-a-retrospective-chart-review
#9
Lydia A Fein, Isabella Rosa Cunha, Brian Slomovitz, JoNell Potter
OBJECTIVE: The aim of the study was to assess risk factors for anal human papillomavirus (HPV) infection and anal dysplasia among a cohort of transgender women (TGW). METHODS: A retrospective chart review was conducted based on electronic medical records of TGW patients seen in the University of Miami Health System between 2010 and 2016. Outcome measures included risk factors of anal dysplasia, including HIV infection, receptive anal intercourse, and smoking history...
March 29, 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29570566/nerve-growth-factor-and-selected-cytokines-in-women-with-and-without-vulvodynia
#10
Barbara D Reed, Melissa A Plegue, Ananda Sen, Hope K Haefner, Javed Siddiqui, Daniel G Remick
OBJECTIVE: The aim of the study was to assess the association between cytokines/neurokines after in vitro stimulation with Candida antigen or lipopolysaccharide (LPS) in blood samples among women with and without vulvodynia. MATERIALS AND METHODS: Women with vulvodynia and asymptomatic controls at three offices at the University of Michigan were examined clinically and completed a comprehensive survey in this cross-sectional study. Cytokine/neurokine levels were determined on blood samples using established ELISA protocols...
April 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29570565/p16-immunohistochemistry-is-not-always-required-for-accurate-diagnosis-of-grade-2-squamous-intraepithelial-lesions
#11
Lulu Sun, Lingxin Zhang, Hannah R Krigman, Ian S Hagemann
OBJECTIVES: Preinvasive squamous neoplasms of the lower genital tract are currently classified using a two-tier system (high- or low-grade squamous intraepithelial lesion) as directed by the Lower Anogenital Squamous Terminology (LAST) guidelines but may also be subclassified as intraepithelial neoplasia grade 1 (-IN1), -IN2, or -IN3. The LAST recommended that all diagnoses of -IN2 be supported by immunohistochemistry (IHC) for p16. We examined whether p16 and Ki-67 IHC are necessary to diagnose -IN2 when the lesion has obvious high-grade histology...
April 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29570564/low-risk-of-cervical-cancer-precancer-among-most-women-under-surveillance-postcolposcopy
#12
Maria Demarco, Li C Cheung, Walter K Kinney, Nicolas Wentzensen, Thomas S Lorey, Barbara Fetterman, Nancy E Poitras, Brian Befano, Philip E Castle, Mark Schiffman
OBJECTIVE: To inform impending postcolposcopy guidelines, this analysis examined the subsequent risk of CIN 3+ among women with a grade lower than CIN 2 (< CIN 2) colposcopy results, taking into account the referring results that brought them to colposcopy and cotest results postcolposcopy. METHODS: We analyzed 107,005 women from 25 to 65 years old, recommended for colposcopy at Kaiser Permanente Northern California. We estimated absolute risks of CIN 3+ among women: (1) recommended for colposcopy (precolposcopy), (2) following colposcopy and with histology results < CIN 2 (postcolposcopy), and (3) with cotest results 12 months after a < CIN 2 colposcopy (return cotest)...
April 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29570563/the-next-generation-of-cervical-cancer-screening-should-guidelines-focus-on-best-practices-for-the-future-or-current-screening-capacity
#13
Phil Castle, Sarah Feldman, Rebecca B Perkins
No abstract text is available yet for this article.
April 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29570562/an-introduction-to-the-new-journal-forum
#14
Rebecca B Perkins, Mark Schiffman, David C Foster
No abstract text is available yet for this article.
April 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29554057/conflict-of-interest-disclosures
#15
(no author information available yet)
No abstract text is available yet for this article.
April 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29481422/anal-and-cervical-high-risk-human-papillomavirus-genotyping-in-women-with-and-without-genital-neoplasia
#16
Amy J Bregar, Beth Cronin, Christine Luis, Paul DiSilvestro, Steven Schechter, Latha Pisharodi, Christina Raker, Melissa Clark, Katina Robison
OBJECTIVE: The aim of the study was to compare the prevalence, genotypes, and rates of concomitant anal and cervical high-risk human papillomavirus (HR-HPV) in women with and without a history of HPV-related genital neoplasia. MATERIALS AND METHODS: This was a prospective cohort study conducted from December 2012 to February 2014. Women with a history of neoplasia were considered the high-risk group. Women without a history of neoplasia were considered the low-risk group...
April 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29474243/anticipating-the-impact-of-human-papillomavirus-vaccination-on-us-cervical-cancer-prevention-strategies
#17
L Stewart Massad
Cervical cancer prevention guidelines are benchmarked to risk of cervical precancer. In younger age cohorts, vaccination against high-risk types of human papillomavirus (HPV) has reduced HPV 16/18 prevalence and cervical intraepithelial neoplasia. Lower prevalence of precancer will impair the sensitivity of cytology and colposcopy, but negative predictive value will rise. Training and skills maintenance will become more difficult as abnormalities become less common. Primary screening with HPV assays will become more attractive but will require HPV genotyping as most positive HPV tests will reflect non-16/18 infections with lower oncogenicity...
April 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29474242/cervical-adenocarcinoma-a-comparison-of-the-reproducibility-of-the-world-health-organization-2003-and-2014-classifications
#18
Aylin Sar, Qiuli Duan, Moosa Khalil, Lisa M DiFrancesco, Carol Ewanowich, Alice Lytwyn, Bojana Djordjevic, Doha Itani, Sandra Lee, Martin Köbel, Sarah Glaze, Elena Park, Máire A Duggan
OBJECTIVE: The aim of the study was to compare the reproducibility of malignant glandular tumors of the uterine cervix classified per World Health Organization (WHO) 2003 and 2014. MATERIALS AND METHODS: Two pathologists reviewed 228 cases composed of adenocarcinoma in situ and 22 adenocarcinoma histotypes and selected 405 representative hematoxylin and eosin slides, which were digitally scanned. Six other pathologists (3 gynecological and 3 anatomical) independently reviewed and classified the images per both WHO classifications...
April 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29474241/reduced-antifungal-susceptibility-of-vulvovaginal-candida-species-at-normal-vaginal-ph-levels-clinical-implications
#19
Mark Spitzer, Nathan P Wiederhold
OBJECTIVE: The aims of the study were to assess for differences in antifungal in vitro potency at pH 7 and pH 4 and to discuss any potential clinical implications of that difference. MATERIALS AND METHODS: A retrospective analysis of 217 first positive yeast cultures from 217 patients. Yeast isolates underwent antifungal susceptibility testing, with minimum inhibitory concentrations (MICs) (microgram per milliliter) measured at pH 7 and pH 4 for fluconazole, itraconazole, miconazole, clotrimazole, terconazole, and nystatin...
April 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29474239/-the-future-of-vulvar-disease-new-and-ongoing-challenges-presidential-lecture-xxiv-world-congress-2017-mendoza-argentina
#20
Claudia Marchitelli
The 21st century brought along a number of discoveries and medical advances. With the advances, we can mention the following: target therapies for cancer, genomics and molecular biology, pharmacogenomics, minimally invasive and robotic surgery, immunosuppressive therapies in transplant patients, human papillomavirus in the era of vaccination, and aesthetic vulvovaginal procedures. All of them have greatly influenced medicine. As a scientific society, we have several challenges. In the past, you had to go to a library to get information...
April 2018: Journal of Lower Genital Tract Disease
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