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Journal of Lower Genital Tract Disease

Yun Liang, Bingjian Lü, Caiyun Zhou
OBJECTIVE: The aims of this study were to clarify the histological features of adenoid basal carcinoma (ABC) and determine whether cytokeratin 17 (CK17) and Ki-67 can facilitate the differential diagnosis of ABC from squamous cell carcinoma (SCC). MATERIALS AND METHODS: Nine cases of pure ABC were collected from the files of the Division of Pathology at the Zhejiang University Hospital Women's School of Medicine. For comparison, 20 cases of moderately to poorly differentiated cervical SCC, including 2 of basaloid SCC, were also retrieved from the same period...
August 13, 2018: Journal of Lower Genital Tract Disease
Ali E McGregor, Kimberly Gecsi
OBJECTIVE: The aim of the study was to determine whether treating all patients older than 25 years with high-grade squamous intraepithelial lesion (HSIL) Paps with immediate loop electrode excisional procedure (LEEP) improves rates of receiving indicated treatment and evaluating whether this practice results in overtreatment (defined by excisional pathology less than cervical intraepithelial neoplasia 2). MATERIALS AND METHODS: This was a retrospective cohort study at an urban, Medicaid-based clinic, which evaluated women older than 25 years with HSIL Pap results seen from June 2011 to December 2016...
August 13, 2018: Journal of Lower Genital Tract Disease
Herschel W Lawson, Mona Saraiya
No abstract text is available yet for this article.
August 6, 2018: Journal of Lower Genital Tract Disease
Emilie Demarquet, Julien Mancini, Lise Preaubert, Jean Gondry, Julien Chevreau, Gery Lamblin, Karine Lebail, Vincent Lavoué, Marion Pinsard, Jean-Jacques Baldauf, Angélique Bryand, Sebastien Henno, Aubert Agostini, Serge Douvier, Adelaïde Jarniat, Didier Riethmuller, Anne Mendel, Jean-Luc Brun, Hajanirina Rakotomahenina, Xavier Carcopino
OBJECTIVE: The aim of the study was to identify the risk factors of post-large loop excision of the transformation zone (LLETZ) recurrent disease and the impact of colposcopic guidance at the time of LLETZ on that risk. MATERIALS AND METHODS: From December 2013 to July 2014, 204 patients who had undergone LLETZ for the treatment of high-grade intraepithelial lesion with fully visible cervical squamocolumnar junction were included. The use of colposcopy during each procedure was systematically documented...
August 6, 2018: Journal of Lower Genital Tract Disease
Amy L Stenson, Catherine Leclair
Periclitoral masses are uncommon disorders in gynecology often leading to pain and distress. With the popularity of female genital hair grooming and depilation, the vulva has been exposed to new insults including contact dermatitis and folliculitis. The unique anatomy of the protective covering of the clitoral hood may subject hair fragments to trapping, inflammation, irritation, and in some cases abscess formation.
August 2, 2018: Journal of Lower Genital Tract Disease
Wen Chen, Haikui Sun, Anco Molijn, Liang Zeng, Leni Kang, David Jenkins, Shaokai Zhang, Jianfeng Cui, Zeni Wu, Edyta Pirog, Guihua Shen, Xun Zhang, Youlin Qiao
OBJECTIVE: A hospital-based multicenter, retrospective study was conducted to compare the distribution of human papillomavirus (HPV) in squamous cell carcinoma (SCC) and cervical adenocarcinoma (CADC) in China. METHODS: Paraffin-embedded tissue blocks diagnosed as SCC and CADC across China were collected, as well as the total number of diagnosed invasive cervical cancer of the 9 selected centers. DNA enzyme immunoassay, reverse hybridization, and multiplex type-specific polymerase chain reaction were used for HPV genotyping...
August 2, 2018: Journal of Lower Genital Tract Disease
Meheret Endeshaw, Tainya Clarke, Virginia Senkomago, Mona Saraiya
OBJECTIVE: The aim of the study was to provide national estimates of Pap test receipt, by birthplace, and percent of lifetime in the United States (US). MATERIALS AND METHODS: Pooled nationally representative data (2005, 2008, 2013, 2015) from the National Health Interview Survey were used to examine differences in Pap test receipt among adult US women by birthplace and percent of lifetime in the US. Descriptive estimates were age-adjusted. Regression models were adjusted for selected sociodemographic and healthcare access and utilization factors and presented as predicted margins...
July 30, 2018: Journal of Lower Genital Tract Disease
T Clark Powell, Sarah E Dilley, Sejong Bae, J Michael Straughn, Kenneth H Kim, Charles A Leath
OBJECTIVES: Despite screening, disparities exist in cervical cancer incidence and outcomes. Demographic factors are associated with diagnosis at advanced stage (AS), but less is known about geographic factors. We sought to investigate risk factors for developing AS cervical cancer in Alabama. MATERIALS AND METHODS: We identified women treated for cervical cancer from 2005 to 2015 at our institution. Stages II-IV were considered AS. ZIP codes were categorized by federal Rural-Urban Commuting Area Codes, and 16 historically underserved counties were categorized as Black Belt rural...
July 30, 2018: Journal of Lower Genital Tract Disease
Rachael B Davenport, Catherine R Voutier, Emma C Veysey
OBJECTIVE: The objective of this study was to detail the outcome measurement instruments used in randomized control trials and observational studies investigating therapeutic interventions for provoked vulvodynia. MATERIALS AND METHODS: We searched Ovid Medline, Embase, Emcare, and PyschINFO libraries from database inception through April 2017. We included randomized control trials and observational studies of provoked vulvodynia that used instruments to measure the outcome of therapeutic interventions...
July 27, 2018: Journal of Lower Genital Tract Disease
Nekma Meah, Sreedhar Subramanian, Nitin Khirwadkar, Tristan Cope, Hazel Bell
No abstract text is available yet for this article.
July 21, 2018: Journal of Lower Genital Tract Disease
Tania Day, Julie Weigner, James Scurry
OBJECTIVES: Three types of lichen planus (LP) occur on the vulva: erosive, classic, and hypertrophic. The latter 2 occur on keratinized skin and little is known about their clinicopathologic appearance. MATERIALS AND METHODS: Vulvar biopsies of keratinized skin reported as LP or "lichenoid" between 2011 and 2017 were reviewed. Inclusion required age of older than 18 years, a lichenoid tissue reaction, and insufficient abnormal dermal collagen to diagnose lichen sclerosus...
July 9, 2018: Journal of Lower Genital Tract Disease
Pedro Vieira-Baptista, Gutemberg Almeida, Fabrizio Bogliatto, Tanja Gizela Bohl, Matthé Burger, Bina Cohen-Sacher, Karen Gibbon, Andrew Goldstein, Debra Heller, Wendy Likes, Celene Longo da Silva, Claudia Marchitelli, Micheline Moyal-Barracco, Kathleen Posey, Maria Celeste Sluga, Colleen Kennedy Stockdale, Gisele Vissoci Marquini, Kamil Zalewski
Female genital cosmetic surgeries (FGCSs) and procedures are increasingly being advertised as common, simple, and complication-free, capable of not only improving aesthetic appearance but also increasing self-esteem and sexual pleasure.Guidelines for physicians and clear, scientifically correct information for patients must be made available, to minimize the number of ineffective or deleterious procedures.The International Society for the Study of Vulvovaginal Disease positions/recommendations regarding FGCS are as follows:1...
July 9, 2018: Journal of Lower Genital Tract Disease
Diana T Medina-Laabes, Erick L Suarez-Perez, Humberto M Guiot, Cristina Muñoz, Vivian Colón-López, Maribel Tirado-Gómez, Ana Patricia Ortiz
OBJECTIVE: To estimate the magnitude of association between anal infection with high-risk human papilloma virus (HR-HPV) types and severity of biopsy-confirmed histopathological anal squamous intraepithelial lesions (SILs) among a clinic-based sample of HIV-infected adults in Puerto Rico. METHODS: This cross-sectional study analyzed data from medical records of adult patients who visited a specialized anal neoplasia clinic from June 2015 to December 2017 (n = 239); sociodemographics, behavioral risk factors, medical history, clinical data, and pathology reports were collected...
July 2, 2018: Journal of Lower Genital Tract Disease
Rosalind C Simpson, Ruth Murphy, Daniel J Bratton, Matthew R Sydes, Sally Wilkes, Helen Nankervis, Shelley Dowey, Hazel Bell, Margaret Cruickshank, Karen Gibbon, Cathy M Green, Christina Wong, Caroline M Owen, Kate London, Shaheen Haque, Kim S Thomas
No abstract text is available yet for this article.
July 2, 2018: Journal of Lower Genital Tract Disease
Margaret E Long, Paula D M Chantigian, Amy L Weaver
OBJECTIVES: The ideal frequency of cervical cancer screening in women with solid organ transplants (SOTs) remains to be determined. We aimed to assess the longitudinal rates of cytologic and histologic cervical abnormalities in women after SOT. METHODS: We retrospectively reviewed health records of women aged 18 to 60 years who received their first kidney, liver, pancreas, or combination transplant at Mayo Clinic (Rochester, Minnesota) from 1995 through 2011. Patient demographics, cervical cytology and histology, and high-risk human papillomavirus (hrHPV) testing data were abstracted...
June 28, 2018: Journal of Lower Genital Tract Disease
Tess Crouss, Jack D Sobel, Katharine Smith, Paul Nyirjesy
OBJECTIVES: Data about long-term clinical outcome after a course of maintenance fluconazole in those with recurrent vulvovaginal candidiasis (RVVC) is lacking. We aimed to determine the rate of recurrence at a minimum of 6 months after completion of maintenance therapy. METHODS: A retrospective analysis of women with Candida albicans RVVC from January 2008 to January 2017 was performed using chart review to obtain information about recurrence after maintenance therapy...
June 28, 2018: Journal of Lower Genital Tract Disease
Annick Pina, Philippe Sauthier, François Coutlée, Helen Trottier, Marie-Hélène Mayrand
As per the American Society for Colposcopy and Cervical Pathology guidelines, human papillomavirus (HPV) testing is currently used as part of cervical cancer screening and during colposcopy follow-up. The present project evaluated if the application of acetic acid (AA) impacts HPV test results. METHODS: We conducted a prospective nonrandomized interventional study. Participants referred for colposcopy were eligible if immunocompetent, older than 18 years, and not pregnant. Women in group A (controls) received 2 consecutive HPV tests without application of AA...
June 27, 2018: Journal of Lower Genital Tract Disease
Meritxell Munmany, Aureli Torné, Roser Nonell, Esther Barnadas, Nerea Luqui, Jaume Ordi, Marta Del Pino
OBJECTIVE: The aim of the study was to assess the accuracy of colposcopy evaluation at the time of the loop electrosurgical excision procedure (LEEP) to identify women with a previous confirmatory diagnosis of squamous intraepithelial lesion/cervical intraepithelial neoplasia (SIL/CIN) with low probability of dysplasia in the LEEP specimen. MATERIALS AND METHODS: We prospectively recruited a cohort of 162 women undergoing LEEP for histological high-grade SIL/CIN 2-3 or low-grade SIL/CIN 1 with high-grade SIL cytology showing a fully visible squamocolumnar junction in the colposcopy evaluation at the time of LEEP...
June 27, 2018: Journal of Lower Genital Tract Disease
Mario Preti, Leonardo Micheletti, Silvana Privitera, Gianluigi Radici, Niccolò Gallio, Chiara Benedetto, Lauro Bucchi
No abstract text is available yet for this article.
July 2018: Journal of Lower Genital Tract Disease
Bethany A Croker, James P Scurry, Frances M Petry, Gayle Fischer
OBJECTIVES: The aims of this case series were to present a series of patients with clinical and histopathological findings consistent with a recently described condition vestibular sclerosis (VS) and to contribute to the current discussion of whether VS is a subset of lichen sclerosus (LS) or a distinct entity. MATERIALS AND METHODS: This case series of 6 women for a 12-month period was initiated from an ongoing collaboration between a gynecological dermatologist and an anatomical pathologist specializing in gynecological dermatopathology...
July 2018: Journal of Lower Genital Tract Disease
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