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Dermatologic Therapy

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https://www.readbyqxmd.com/read/28097731/efficacy-and-tolerability-of-amorolfine-5-nail-lacquer-in-combination-with-systemic-antifungal-agents-for-onychomycosis-a-meta-analysis-and-systematic-review
#1
REVIEW
Xiaowei Feng, Xincai Xiong, Yuping Ran
The efficacy and safety of amorolfine 5% nail lacquer in combination with systemic antifungal agents in the treatment of the onychomycosis were evaluated. According to our meta-analysis, combination treatment of amorolfine 5% nail lacquer and systemic antifungals can result in higher percentage of complete clearance of onychomycosis. It showed that the experimental combination group was more effective than monotherapy of the systemic antifungals [OR (odds ratio) = 1.97, 95%CI (95% confidence interval) = 1...
January 18, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28071837/use-of-tnf-inhibitors-and-ustekinumab-for-psoriasis-during-pregnancy-a-patient-series
#2
Tamara Lund, Simon Francis Thomsen
From 2002 to 2016 a total of seven women with severe refractory psoriasis were exposed to the TNF-inhibitors infliximab and adalimumab or to the IL12/23 inhibitor ustekinumab during one or more pregnancies. Maternal, fetal or teratogenic toxicity were not detected during pregnancy and puerperium. All pregnancies were uneventful and resulted in delivery of 10 healthy children in total, one of the women is due February 2017. Postpartum, five of the women were lactating, but none of the women or newborns developed adverse reactions...
January 10, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28032675/retinoic-acid-for-treatment-of-systemic-sclerosis-and-morphea-a-literature-review
#3
REVIEW
Renee M Thomas, Scott Worswick, Maria Aleshin
Systemic sclerosis and morphea are connective tissue diseases characterized by tightening, thickening, and hardening of the skin, leading to significant morbidity. Unfortunately, current treatment options have limited efficacy for many patients. Cutaneous manifestations of these diseases arise from excess collagen deposition and fibrosis in the skin, through pathogenic mechanisms which have yet to be extensively detailed at the causal immune and cellular levels. Research elucidating the mechanism of action of retinoic acid on collagen production in the skin and case series highlighting the success of retinoic acid on the skin manifestations of systemic sclerosis and on morphea demonstrate its promise as a treatment...
December 29, 2016: Dermatologic Therapy
https://www.readbyqxmd.com/read/27998025/effect-of-different-types-of-therapeutic-trauma-on-vitiligo-lesions
#4
Medhat El Mofty, Samia Esmat, Nahla Hunter, Heba M Mashaly, Dina Dorgham, Olfat Shaker, Sarah Ibrahim
New treatment modalities for vitiligo acting by changing certain cytokines and metalloproteinases are newly emerging. The aim of this work is to To assess the efficacy of trichloroacetic acid (TCA) chemical peel, dermapen, and fractional CO2 laser in treatment of stable non-segmental vitiligo and to detect their effects on IL-17 and MMP-9 levels. Thirty patients with stable vitiligo were recruited in a randomized controlled study. They were randomly categorized into three equal groups. Group 1: TCA peel, Group 2: dermapen machine, and Group 3: Fractional CO2 laser...
December 20, 2016: Dermatologic Therapy
https://www.readbyqxmd.com/read/27998019/optimizing-acitretin-use-in-patients-with-plaque-psoriasis
#5
Andrea Chiricozzi, Salvatore Panduri, Valentina Dini, Annalisa Tonini, Bruno Gualtieri, Marco Romanelli
Acitretin is one of the systemic agents used for the treatment of psoriasis. Because different acitretin dosages resulted therapeutically successful, there is no general agreement on the optimal dose regimen. To report acitretin efficacy and safety in a real-life setting, wherein patient-tailored dose regimen is usually prescribed, a retrospective analysis evaluating charts of all plaque-type psoriasis patients treated with acitretin from the clinic database was performed. PASI score improvement, as well as PASI 50, 75, 90, and 100 responses were assessed throughout the observational period...
December 20, 2016: Dermatologic Therapy
https://www.readbyqxmd.com/read/27917579/novel-technique-for-repigmentation-of-senescence-grey-hair
#6
Andy Goren, Željana Bolanča, Torello Lotti, Mirna Šitum
No abstract text is available yet for this article.
December 5, 2016: Dermatologic Therapy
https://www.readbyqxmd.com/read/27917575/efficacy-and-tolerability-of-a-new-topical-nitric-zinc-preparation-for-difficult-to-treat-warts
#7
Camila K Janniger, Robert A Schwartz
Treating plantar, periungual, and external genital warts can be challenging. A prospective study from four centers in Italy evaluated 37 immunocompetent patients with single or multiple warts and treated each lesion with a nitric-zinc topical solution composed of organic and inorganic acids meant to devitalize tissue and destroy HPV DNA in infected keratinocytes. Thirty of the 37 patients had external genital warts, two had plantar warts, two had palm and finger warts, and three had subungual warts for a total of 55 lesions treated...
December 5, 2016: Dermatologic Therapy
https://www.readbyqxmd.com/read/27891740/minocycline-successfully-treats-exaggerated-granulomatous-hypersensitivity-reaction-to-mw-immunotherapy
#8
Keshavamurthy Vinay, Tarun Narang, Uma N Saikia, Muthu Sendhil Kumaran, Sunil Dogra
Mycobacterium W (Mw) vaccine has been found to be effective in the treatment of leprosy and warts. Despite increasing use of Mw immunotherapy, data on its safety is limited. We report a series of eight patients who developed persisting injection site granulomatous reaction following Mw immunotherapy and were successfully treated with minocycline. Eight patients with persistent nodular swelling at the site of Mw injections were identified. Seven of them had received Mw immunotherapy for cutaneous warts and one for verrucous epidermal nevus...
November 28, 2016: Dermatologic Therapy
https://www.readbyqxmd.com/read/27891738/treatment-of-prurigo-nodularis-with-lenalidomide
#9
Lidia Ossorio-García, David Jiménez-Gallo, María Eugenia Rodríguez-Mateos, Cintia Arjona-Aguilera, Mario Linares-Barrios
Prurigo nodularis (PN) is an intensely pruriginous dermatological disorder whose treatment is challenging for dermatologists. It is characterized by eruptions of papules and hyperkeratotic nodules, some of which are eroded, on the extensor surfaces of the limbs. The most commonly used treatments for this condition are oral antihistamines and topical or systemic steroids. Thalidomide is an effective treatment option in cases of recalcitrant PN; however, its most frequent adverse effect is neurotoxicity, which often results in its discontinuation...
November 28, 2016: Dermatologic Therapy
https://www.readbyqxmd.com/read/27891734/impending-skin-necrosis-after-dermal-filler-injection-a-golden-time-for-first-aid-intervention
#10
Ji Yeon Hong, Joon Seok, Ga Ram Ahn, Yu-Jin Jang, Kapsok Li, Beom Joon Kim
Vascular compromise with impending skin necrosis is one of the most serious potential complications. Early recognition of vascular occlusion and swift and aggressive treatment are required to avoid any irreversible changes. However, initial symptoms of a vascular event are often dismissed as simple post-procedural discomfort. If more than 3 days pass after filler injection, crust formation is initiated over the erythematous base along with a rim of fibrous tissue. Due to the replacement of normal tissues by fibrous material, the healing process may result in scar formation in spite of debridement and aggressive dressing changes...
November 28, 2016: Dermatologic Therapy
https://www.readbyqxmd.com/read/27891733/generalized-granulomatous-dermatitis-following-mycobacterium-w-mw-immunotherapy-in-lepromatous-leprosy
#11
Geeti Khullar, Tarun Narang, Uma Nahar Saikia, Sunil Dogra
Mycobacterium w (Mw) vaccine is a heat-killed suspension derived from a nonpathogenic, cultivable, atypical mycobacterium named Mycobacterium indicus pranii. Mw immunotherapy has been reported to be efficacious as an adjunct to multidrug therapy multibacillary regimen in leprosy patients with high bacillary index. Cutaneous reactions are predominant adverse effects associated with the administration of vaccines. Cutaneous adverse effects ascribed to Mw vaccine are generally limited to the site of injection...
November 28, 2016: Dermatologic Therapy
https://www.readbyqxmd.com/read/27891741/combination-treatment-of-propranolol-minocycline-and-tranexamic-acid-for-effective-control-of-rosacea
#12
Hyun Jung Kwon, Joon Hyuk Suh, Eun Jung Ko, Beom Joon Kim
No abstract text is available yet for this article.
November 27, 2016: Dermatologic Therapy
https://www.readbyqxmd.com/read/27891730/reduction-in-psoriasis-related-pruritus-during-biologic-therapy
#13
L Lazzeri, L Pescitelli, L Tripo, F Ricceri, F Prignano
No abstract text is available yet for this article.
November 27, 2016: Dermatologic Therapy
https://www.readbyqxmd.com/read/27891708/n-acetyl-cysteine-in-the-treatment-of-trichotillomania
#14
Katlein França, Torello Lotti
No abstract text is available yet for this article.
November 27, 2016: Dermatologic Therapy
https://www.readbyqxmd.com/read/27886445/beard-hair-density-increase-a-possible-role-of-topical-tretinoin-application
#15
Michelangelo Vestita, Giuseppe Giudice, Domenico Bonamonte, Doriana Apruzzi, Angela Filoni
No abstract text is available yet for this article.
November 25, 2016: Dermatologic Therapy
https://www.readbyqxmd.com/read/27860166/treatment-of-antiviral-resistant-recurrent-erythema-multiforme-with-dapsone
#16
Allen S W Oak, Lucia Seminario-Vidal, Naveed Sami
Recurrent erythema multiforme (REM) is a chronic disease characterized by frequent episodes of target cutaneous lesions in an acral distribution. Conventional treatment includes systemic corticosteroids and antiviral therapy. The aim of this study was to evaluate dapsone as a potential steroid sparing-agent for the treatment of REM after a failed trial of at least one antiviral therapy (acyclovir, famciclovir, or valacyclovir). A retrospective chart review was conducted on thirteen patients with a diagnosis of REM who underwent treatment with dapsone after failing at least one antiviral therapy...
November 18, 2016: Dermatologic Therapy
https://www.readbyqxmd.com/read/27859984/successful-management-of-disseminated-superficial-actinic-porokeratosis-with-diclofenac-sodium-3-gel
#17
María-Mercedes Otero-Rivas, Romina Rodríguez-Lojo, Iria-Margarita Castiñeiras-Mato, Mercedes Lueiro-Vilariño, Yolanda Juárez-Casado, María-Luisa Fernández-Díaz
No abstract text is available yet for this article.
November 18, 2016: Dermatologic Therapy
https://www.readbyqxmd.com/read/27862813/multiple-papular-eruptions-at-insertion-site-of-gold-coated-polydioxanone-thread
#18
Joon Seok, Kui Young Park, Kapsok Li, Beom Joon Kim, Seong Jun Seo, Myeung Nam Kim, Chang Kwun Hong, Kye Yong Song
No abstract text is available yet for this article.
November 12, 2016: Dermatologic Therapy
https://www.readbyqxmd.com/read/27862787/two-diseases-one-remedy-systemic-amyloidosis-secondary-to-hidradenitis-suppurativa-treatment-with-infliximab
#19
İlkay Özer, Cengiz Karaçin, Esra Adışen, Galip Güz, Mehmet Ali Gürer
Hidradenitis suppurativa, known as acne inversa, is a relapsing and chronic inflammatory skin disease affecting the skin folds. During the chronic course of the disease many local complications like fistulae to other tissues or systemic complications including anemia, secondary amyloidosis, lymphedema, nephrotic syndrome, artropathy may take place. Amyloid A amyloidosis is a rare complication of hidradenitis suppurativa, which has been described in a limited number of case reports. Herein, we present such a patient that had developed AA amyloidosis during the course of hidradenitis suppurativa...
November 12, 2016: Dermatologic Therapy
https://www.readbyqxmd.com/read/27862745/infliximab-induced-cutaneous-eruption-resembling-pityriasis-rubra-pilaris-in-a-patient-with-takayasu-s-arteritis
#20
Andac Salman, Yaman Sonmez, Hulya Sahin, Ali Ugur Unal, Haner Direskeneli, Leyla Cinel, Tulin Ergun
No abstract text is available yet for this article.
November 12, 2016: Dermatologic Therapy
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