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Dermatologic Therapy

Sima Rasaii, Nasibe Sohrabian, Serena Gianfaldoni, Nader Pazyar, Alireza Bakhshaeekia, Torello Lotti, Luis A Ramirez-Pacheco, Christopher S Lange, Jaime Matta, Vahid Seifi, Maryam Hadibarhaghtalab, Marigdalia K Ramirez-Fort, Amir Feily
Cutaneous injury can ignite excessive fibroproliferative growth that results in keloid formation. Keloids are associated with significant morbidity related to disfigurement and/or symptoms (e.g. pain, pruritus). First-line treatment of formed keloids involves topical or intralesional steroids. Recurrent or resistant keloids are managed by surgical excision or cryotherapy, followed by steroidal application or adjuvant irradiation. While adjuvant irradiation appears to be most efficacious, alternative therapeutic options are needed for patients without access to radiation centers...
November 13, 2018: Dermatologic Therapy
Paolo Amori, Veronica Di Nardo, Gabriella Vitiello, Katlein Franca, Jana Hercogova, Uwe Wollina, Farah Daaboul, Georgi Tchernev, Torello Lotti
Vulvovaginal atrophy is a condition that affects women, although it is mainly associated with the onset of menopause mainly due to hormonal changes vulvovaginal laxity and mucosal atrophy can also affect women at different life stages such as after pregnancy or for cancer patients who have undergone chemo or endocrine therapy. This condition negatively influence quality of life, sexual desire, and self-confidence. Many therapies have been considered mainly with inconclusive or transient results in terms of benefit factor...
November 8, 2018: Dermatologic Therapy
Ayman Abdelmaksoud, Michelangelo Vestita
Psoriasis is a chronic inflammatory disease that has been associated to liver disease, includinghepatitis C virus infection. TNF-α is a key cytokine for both hepatitis C progression and psoriasis. HCV high-prevalence countries are likely to show clear association of the two conditions. We reviewed the current literature on the effect of anti-HCV therapy on the course of psoriasis in patient affected with both diseases.
November 5, 2018: Dermatologic Therapy
Dong Uk Cheon, Young Suck Ro, Jeong Eun Kim
No abstract text is available yet for this article.
November 5, 2018: Dermatologic Therapy
Magdy Abd El Aziz Ragab, Salma Samir Omar, Andrew Collier, Reham Abdel Haleem Abo El-Wafa, Neveen Gomaa
The continuous low dose (LD) isotretinoin is frequently used in the treatment regimen for acne vulgaris. However, data about its antimicrobial are lacking. The present study aimed to investigate dermcidin expression and the effects of low and conventional dose isotretinoin on its expression in acne vulgaris patients. Skin dermcidin expression was investigated in 30 patients with moderate-severe acne vulgaris and 15 healthy control subjects using ELISA. 15 patients were given continuous low-dose isotretinoin (20 mg/day) and the other 15 given the conventional high dose (0...
November 5, 2018: Dermatologic Therapy
Robert A Schwartz
No abstract text is available yet for this article.
November 5, 2018: Dermatologic Therapy
Guk Jin Jeong, Hyun Jung Kwon, Kui Young Park, Beom Joon Kim
Fillers have become popular worldwide as the demand for enhancements in rejuvenating effects and esthetic improvements is continually increasing. With broader applications and the increasing number of cosmetic procedures using fillers, more filler-related complications are being reported. These filler-related complications range from mild bruising to severe vascular complications. Because of the severe and irreversible outcomes of vascular complications, treatment protocols for such complications are being investigated and updated actively...
November 5, 2018: Dermatologic Therapy
Clothilde Börjesson, Elisabeth Guinard, Marie Tauber, Maria-Polina Konstantinou, Cristina Bulai Livideanu, Juliette Mazereeuw-Hautier, Nicolas Meyer, Carle Paul
BACKGROUND: Compounded topical preparations (CTP) were used to treat psoriasis until the last century and have disappeared from guidelines. CASE REPORT: We report two severe psoriasis patients who were treated with CTP. A man had psoriasis with a PASI of 23 and a body surface area (BSA) of 43%. He had been using daily for several weeks a CTP including minoxidil, clobetasol propionate and hydroxyprogesterone formulated in an alcohol based vehicle. A woman suffered from psoriasis with an annular inflammatory pattern and a central healing...
November 2, 2018: Dermatologic Therapy
Leonardo Celleno
Alterations in barrier function are associated with a number of skin diseases, including xerosis, atopic dermatitis, and psoriasis. Urea, a component of the natural moisturizing factor of the skin, plays an important role in the preservation of skin hydration and integrity. Several studies have investigated the effects of urea in the clinical setting. Here, we summarize the available clinical evidence regarding the effects of urea in the maintenance of healthy skin and management of skin disorders. At lower doses (≤10%), urea-containing topical formulations act as a skin moisturizer, while at higher concentrations (>10% urea), urea-based preparations exert a keratolytic action...
October 30, 2018: Dermatologic Therapy
Federico Bardazzi, Miriam Leuzzi, Francesca Ferrara, Annalisa Patrizi, Camilla Loi
No abstract text is available yet for this article.
October 29, 2018: Dermatologic Therapy
Giovanni Brotzu, Anna Maria Fadda, Maria Letizia Manca, Thomas Manca, Francesca Marongiu, Monica Campisi, Francesca Consolaro
Hair loss is a common aesthetic disorder that can be triggered by genetic, inflammatory, hormonal, and environmental factors acting on hair follicles and their life cycle. There are several types of hair loss that differ in causes, symptoms, and spatial and temporal progression. Androgenic alopecia, a common form of hair loss, is the consequence of a decreased microcirculation of the scalp as well as the toxic action of elevated dihydrotestosterone levels on the hair bulbs. In the present study, the lotions TRINOV Lozione Anticaduta Uomo and TRINOV Lozione Anticaduta Donna, containing dihomo-γ-linolenic acid (DGLA), S-equol, and propionyl-L-carnitine, were tested on 30 men and 30 women (mean age of men was 46...
October 29, 2018: Dermatologic Therapy
Parastoo Pourali, Behrooz Yahyaei
PURPOSE: Although alginate has been known to be a good wound dressing, it does not have antimicrobial properties, has low availability, and is expensive. In order to overcome these problems, this study was conducted, where the extraction of this material from an available small factory Pseudomonas aeruginosa and the improvement of its wound healing property by its combination with herb extract, Alhagi maurorum, done. METHODS: Nineteen P. aeruginosa strains were isolated and identified from burned skin and one isolated strain with the highest ability of alginate production was selected...
October 29, 2018: Dermatologic Therapy
Shoichiro Minami, Kayoko Minami, Hiroyuki Iwata
No abstract text is available yet for this article.
October 28, 2018: Dermatologic Therapy
Gulcan Saylam Kurtipek, Nihal Sarı, Fatma Tunçez Akyürek
Geographical tongue, also known as benign migratory glossitis or erythema migrans, is a benign dermatosis whose spesific etiology is not known due to the disappearance of central erythematous and filiform papillaries surrounded by a hyperkeratotic ring forming the geographical shape on the tongue. In treatment, topical corticosteroids may be recommended for symptomatic relief. Pregabalin is a drug with, GABA analog structure. Pregabalin is a drug used and investigated in epilepsy, neuropathic pain, anxiety, and sleep disorders...
October 26, 2018: Dermatologic Therapy
Jin Ok Baek, Jeong Soo Kim, Seul Ki Lee, Ji Hun Jeong, Myung Jin Lee, Il Hye Seo
Nocardiosis is a rare localized or systemic suppurative disease caused by the actinomycete Nocardia species. The respiratory tract is the most common site of infection, but primary cutaneous nocardiosis can also be induced by direct inoculation. Nocardiosis is usually reported in immunocompromised patients, such as those with human immunodeficiency virus (HIV) infection, chronic obstructive pulmonary disease, autoimmune diseases, cancer, or in those who have had organ transplantation or corticosteroid administration...
October 26, 2018: Dermatologic Therapy
Sacchelli Lidia, Patrizi Annalisa, Ferrara Francesca, Bardazzi Federico
No abstract text is available yet for this article.
October 24, 2018: Dermatologic Therapy
Jun Ren, Li-Yue Zeng, Mei-Hua Chen
No abstract text is available yet for this article.
October 24, 2018: Dermatologic Therapy
Molka Ariane, Jean-David Bouaziz, Adèle de Masson, Marie Jachiet, Martine Bagot, Clémence Lepelletier
Non peristomal postoperative pyoderma gangrenosum (PPG) is a rare subtype of pyoderma gangrenosum that occurs in the early postoperative period at surgical incisions, most commonly after breast surgery. Early diagnosis and treatment is essential to prevent severe scaring. TNF alpha inhibitor infliximab was reported to be efficient in treatment of PPG refractory to systemic corticosteroids. However infliximab can be not well tolerated. We report the first case of etanercept efficacy in post-plastic breast surgery pyoderma gangrenosum after infliximab serum sickness...
October 20, 2018: Dermatologic Therapy
Shawn Shih
No abstract text is available yet for this article.
October 19, 2018: Dermatologic Therapy
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