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Dermatologic Therapy

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https://www.readbyqxmd.com/read/28940579/treatment-of-psoriasis-with-topical-agents-recommendations-from-a-tuscany-consensus
#1
Andrea Chiricozzi, Nicola Pimpinelli, Federica Ricceri, Giovanni Bagnoni, Laura Bartoli, Mauro Bellini, Luca Brandini, Marzia Caproni, Antonio Castelli, Michele Fimiani, Franco Marsili, Carlo Mazzatenta, Maria Chiara Niccoli, Salvatore Panduri, Michele Pellegrino, Riccardo Sirna, Walter Volpi, Marco Romanelli, Francesca Prignano
Psoriasis is a chronic and relapsing inflammatory skin disease, clinically characterized by erythematous and scaly plaques. Treatment approach is mainly driven by disease severity, though several factors should be considered in order to identify the optimal therapeutic choice. Mild psoriasis may be treated with a wide array of topical agents including corticosteroids, vitamin D analogs, keratolytics, and calcipotriol/betamethasone propionate compound. Because guidelines may not provide practical indications regarding the therapeutic approach, the use of topical agents in psoriasis is more individually tailored...
September 20, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28906051/effectiveness-and-safety-of-secukinumab-in-69-patients-with-moderate-to-severe-plaque-psoriasis-a-retrospective-multicenter-study
#2
J F Schwensen, A Clemmensen, C Sand, R Gniadecki, L Skov, C Zachariae, L Iversen, M Rasmussen, S F Thomsen
Secukinumab (anti-IL17A) is effective as treatment for moderate to severe plaque psoriasis, but real-life data on effectiveness and safety lack. We aimed to present real-life data of all Danish patients treated with secukinumab (n = 69). At baseline, before initiation of treatment with secukinumab 300 mg (47.8%) or off-label treatment with secukinumab 150 mg (52.2%), the median PASI score was 7.1. A total of 66.7% (34/51) and 52.9% (27/51) of patients still on secukinumab at week 12 achieved a PASI (Psoriasis Area and Severity Index)-50 and PASI-75 of 66...
September 14, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28906049/alitretinoin-treatment-of-lichen-amyloidosis
#3
Won Seon Koh, Eui Hyun Oh, Jeong Eun Kim, Young Suck Ro
Lichen amyloidosis (LA) is characterized by the deposition of amyloid that may respond to chronic scratching that may be secondary to atopic dermatitis, stasis dermatitis, or interface dermatitis. Despite the development of several therapeutic strategies, including topical steroids, oral antihistamines, cyclosporine, and retinoids, an effective treatment for LA has not been established. A 49-year-old woman who has been treated irregularly for atopic dermatitis for 7 years presented with localized brownish papules on the left forearm and right elbow...
September 14, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28892233/hyaluronic-acid-microneedle-patch-for-the-improvement-of-crow-s-feet-wrinkles
#4
Sun Young Choi, Hyun Jung Kwon, Ga Ram Ahn, Eun Jung Ko, Kwang Ho Yoo, Beom Joon Kim, Changjin Lee, Daegun Kim
Hyaluronic acid (HA) has an immediate volumizing effect, due to its strong water-binding potential, and stimulates fibroblasts, causing collagen synthesis, with short- and long-term effects on wrinkle improvement. We investigated the efficacy and safety of HA microneedle patches for crow's feet wrinkles. Using a randomized spilt-face design, we compared microneedle patches with a topical application containing the same active ingredients. We enrolled 34 Korean female subjects with mild to moderate crow's feet wrinkles...
September 11, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28856784/topical-antifungal-treatment-prevents-recurrence-of-toenail-onychomycosis-following-cure
#5
Avner Shemer, Aditya K Gupta, Adaia Kamshov, Meir Babaev, Renata Farhi, C Ralph Daniel, Kelly A Foley
Recurrence rates are high for onychomycosis, with prophylactic topical antifungal use proposed to counter recurrence. Although this is a reasonable action for many clinicians, few studies have been conducted on the efficacy of topical prophylaxis. A retrospective chart review (2010-2015) was conducted in patients receiving oral terbinafine or itraconazole for toenail onychomycosis. Following complete cure, a topical antifungal (amorolfine, bifonazole, ciclopirox olamine, or terbinafine spray) was used weekly as prophylaxis...
August 30, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28836714/completion-dissection-or-observation-for-sentinel-node-metastasis-in-melanoma
#6
Massimo Fioranelli, Maria Grazia Roccia, Carlo Pastore, Carolina Jahaira Aracena, Torello Lotti
No abstract text is available yet for this article.
August 24, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28834139/minocycline-a-strategy-for-unresponsive-nerve-function-impairment
#7
LETTER
Pugazhenthan Thangaraju, Sajitha Venkatesan, Showkath Ali Mk
No abstract text is available yet for this article.
August 23, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28834064/vitamin-d-supplementation-for-vitiligo
#8
LETTER
Nooshin Bagherani, Bruce R Smoller, Torello Lotti
No abstract text is available yet for this article.
August 23, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28834031/uva-1-in-the-treatment-of-alopecia-areata
#9
LETTER
Katlein França, David Castillo, Georgi Tchernev, Torello Lotti
No abstract text is available yet for this article.
August 23, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28834023/crisaborole-a-new-and-effective-nonsteroidal-topical-drug-for-atopic-dermatitis
#10
LETTER
Ajay Kailas
No abstract text is available yet for this article.
August 23, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28833900/treatment-of-oral-lichen-planus-using-308-nm-excimer-laser
#11
Wei-Bing Liu, Li-Wei Sun, Hua Yang, Yan-Fei Wang
Oral lichen planus (OLP) is a chronic inflammatory disease, has prolonged courses, repeated attacks and resistance to treatment. The traditional narrow spectrum UVB treatment has an established efficacy on skin lichen planus, and high safety. However, most of ultraviolet phototherapy devices have a huge volume, thereby cannot be used in the treatment of OLP. Lymphocytic infiltration is evident in the lesions of lichen planus, and the direct irradiation of 308-nm excimer laser can induce apoptosis of the T lymphocytes in skin lesions, thereby has a unique therapeutic effect on the diseases involving T lymphocytes...
August 23, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28834062/generalized-pustular-drug-eruption-caused-by-topical-5-fluorouracil
#12
Kathleen M Nemer, Jason F Solus, Andras Schaffer, Ilana S Rosman, Sena J Lee
No abstract text is available yet for this article.
August 18, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28833974/jak-inhibitors-and-uv-b-potential-combined-therapy-for-vitiligo
#13
Brittany Urso
No abstract text is available yet for this article.
August 18, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28833973/successful-ustekinumab-treatment-of-noninfectious-uveitis-and-concomitant-severe-psoriatic-arthritis-and-plaque-psoriasis
#14
Cristina Mugheddu, Laura Atzori, Maria Del Piano, Astrid Lappi, Monica Pau, Severino Murgia, Ignazio Zucca, Franco Rongioletti
We report the first successful treatment of noninfectious uveitis with ustekinumab in a patient with severe concomitant psoriasis and psoriatic arthritis who failed to respond to conventional immune suppressants and with contraindications to tumor necrosis factor alpha inhibitors.
August 18, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28805286/a-survey-on-monopolar-radiofrequency-treatment
#15
Dong Hye Suh, Eun Sun Hong, Hyun Joo Kim, Sang Jun Lee, Hei Sung Kim
This questionnaire-based study was aimed to measure the level of appreciation, awareness of the special tips, and practice patterns of monopolar radiofrequency among Korean dermatologists practicing a specific monopolar radiofrequency device (Thermage® Inc., Hayward, CA). A total of 82 surveys were analyzed to show that the majority of participants (78.8%) were highly satisfied with the outcomes of monopolar radiofrequency treatment. All respondents were aware of the Eye Tip 0.25 cm(2) , and the majority knew the difference between the Face tip (blue) and the Total tip (orange)...
August 14, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28796428/topical-cetirizine-1-for-treatment-of-androgenetic-alopecia
#16
LETTER
Ayman Abdelmaksoud
No abstract text is available yet for this article.
August 10, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28796405/rate-of-serious-infection-in-patients-who-are-prescribed-systemic-biologic-or-nonbiologic-agents-for-psoriasis-a-large-single-center-retrospective-observational-cohort-study
#17
Chantelle Carneiro, Romi Bloom, Erin Ibler, Sara Majewski, Kimberly A Sable, Nicholas J Guido, Jennifer Day, Salvatore Nocadello, Aleksandra G Florek, Dennis P West, Beatrice Nardone
BACKGROUND: Systemic biologic and nonbiologic agents used to treat psoriasis may or may not contribute to serious infection (SI) risk. Safety data, particularly for biologic agents, and associated risk for SI, are scarce. The study's aim was to explore the risk for SI in psoriasis patients exposed to systemic biologic or nonbiologic agents. METHODS: A large, single-center electronic medical record repository was searched between January 2010 and December 2014. Records for patients prescribed a systemic agent for psoriasis (SAP) with psoriasis or psoriatic arthritis diagnoses were included (ICD-9 codes 696...
August 10, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28796400/methotrexate-for-treatment-of-vitiligo
#18
LETTER
Ayman Abdelmaksoud
No abstract text is available yet for this article.
August 10, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28796343/prevention-of-graying-is-krox20-the-solution
#19
LETTER
Lilia M Correa-Selm, James M Grichnik
No abstract text is available yet for this article.
August 10, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28796288/a-novel-topical-agent-in-the-treatment-of-seborrheic-keratoses-a-proof-of-concept-study-by-clinical-and-dermoscopic-evaluation
#20
Francesco Lacarrubba, Maria Rita Nasca, Anna Elisa Verzì, Giuseppe Micali
In this proof of concept study, 50 lesions from 15 patients with multiple seborrheic keratoses (SKs) were treated with a novel aqueous solution containing nitric acid, zinc and copper salts, and organic acids (acetic, lactic, and oxalic acid). Treatment consisted in the application of an amount of the solution sufficient to obtain a whitening/yellowish reaction. Application of the nitric-zinc solution was performed every other week until clinical and dermoscopic clearance or crust formation, for a maximum of 4 applications...
August 10, 2017: Dermatologic Therapy
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