journal
MENU ▼
Read by QxMD icon Read
search

Stress: the International Journal on the Biology of Stress

journal
https://www.readbyqxmd.com/read/29790822/the-serotonin-transporter-polymorphism-5-httlpr-and-cortisol-stress-responsiveness-preliminary-evidence-for-a-modulating-role-for-sleep-quality
#1
Jens H van Dalfsen, C Rob Markus
The short (S) allele of a functional polymorphism (5-HTTLPR) within the promoter region of the serotonin transporter gene (SLC6A4) is found to predispose the risk for stress-related affective disorders relative to the long (L) allele. Evidence suggests that elevated stress reactivity of the hypothalamic-pituitary-adrenal (HPA) axis might underlie this association although there is little understanding about the origin of inconsistent findings. Since inadequate sleep is commonly known to promote HPA stress reactivity, it might well play an important modulating role...
May 23, 2018: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/29764284/role-of-glucocorticoid-negative-feedback-in-the-regulation-of-hpa-axis-pulsatility
#2
Julia K Gjerstad, Stafford L Lightman, Francesca Spiga
The hypothalamic-pituitary-adrenal (HPA) axis is the major neuroendocrine axis regulating homeostasis in mammals. Glucocorticoid hormones are rapidly synthesized and secreted from the adrenal gland in response to stress. In addition, under basal conditions glucocorticoids are released rhythmically with both a circadian and an ultradian (pulsatile) pattern. These rhythms are important not only for normal function of glucocorticoid target organs, but also for the HPA axis responses to stress. Several studies have shown that disruption of glucocorticoid rhythms is associated with disease both in humans and in rodents...
May 15, 2018: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/29745275/animal-models-of-social-stress-the-dark-side-of-social-interactions
#3
Marianela Masis-Calvo, Anna K Schmidtner, Vinícius E de Moura Oliveira, Cindy P Grossmann, Trynke R de Jong, Inga D Neumann
Social stress occurs in all social species, including humans, and shape both mental health and future interactions with conspecifics. Animal models of social stress are used to unravel the precise role of the main stress system - the HPA axis - on the one hand, and the social behavior network on the other, as these are intricately interwoven. The present review aims to summarize the insights gained from three highly useful and clinically relevant animal models of psychosocial stress: the resident-intruder (RI) test, the chronic subordinate colony housing (CSC), and the social fear conditioning (SFC)...
May 10, 2018: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/29693483/rehabilitation-for-improved-cognition-in-patients-with-stress-related-exhaustion-disorder-reco-a-randomized-clinical-trial
#4
Hanna Malmberg Gavelin, Therese Eskilsson, Carl-Johan Boraxbekk, Maria Josefsson, Anna Stigsdotter Neely, Lisbeth Slunga Järvholm
Stress-related exhaustion has been associated with selective and enduring cognitive impairments. However, little is known about how to address cognitive deficits in stress rehabilitation and how this influences stress recovery over time. The aim of this open-label, parallel randomized controlled trial (ClinicalTrials.gov: NCT03073772) was to investigate the long-term effects of 12 weeks cognitive or aerobic training on cognitive function, psychological health, and work ability for patients diagnosed with exhaustion disorder (ED)...
April 25, 2018: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/29676198/blockade-of-at1-type-receptors-for-angiotensin-ii-prevents-cardiac-microvascular-fibrosis-induced-by-chronic-stress-in-sprague-dawley-rats
#5
Lília Taddeo Firoozmand, Andrea Sanches, Nilsa Regina Damaceno-Rodrigues, Juliana Dinéia Perez, Danielle Sanches Aragão, Rodolfo Mattar Rosa, Fernanda Klein Marcondes, Dulce Elena Casarini, Elia Garcia Caldini, Tatiana Sousa Cunha
To test the effects of chronic-stress on the cardiovascular system, the model of chronic mild unpredictable stress (CMS) has been widely used. The CMS protocol consists of the random, intermittent, and unpredictable exposure of laboratory animals to a variety of stressors, during 3 consecutive weeks. In this study, we tested the hypothesis that exposure to the CMS protocol leads to left ventricle microcirculatory remodeling that can be attenuated by angiotensin II receptor blockade. Male Sprague-Dawley rats were randomly assigned into four groups: Control, Stress, Control + losartan, and Stress + losartan (N = 6, each group, losartan: 20 mg/kg/day)...
April 20, 2018: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/29661114/pasireotide-treatment-does-not-modify-hyperglycemic-and-corticosterone-acute-restraint-stress-responses-in-rats
#6
Antônio Ribeiro-Oliveira, Junia R O L Schweizer, Pedro H S Amaral, Mariana F Bizzi, Warley Cezar da Silveira, Daniel T A Espirito-Santo, Giancarlo Zille, Beatriz S Soares, Herbert A Schmid, Kevin C J Yuen
Pasireotide is a new-generation somatostatin analog that acts through binding to multiple somatostatin receptor subtypes. Studies have shown that pasireotide induces hyperglycemia, reduces glucocorticoid secretion, alters neurotransmission, and potentially affects stress responses typically manifested as hyperglycemia and increased corticosterone secretion. This study specifically aimed to evaluate whether pasireotide treatment modifies glucose and costicosterone secretion in response to acute restraint stress...
April 17, 2018: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/29648498/timing-matters-the-interval-between-acute-stressors-within-chronic-mild-stress-modifies-behavioral-and-physiologic-stress-responses-in-male-rats
#7
Sonia A Cavigelli, Alexander D Bao, Rebecca A Bourne, Michael J Caruso, Jasmine I Caulfield, Mary Chen, Joshua M Smyth
Chronic mild stress can lead to negative health outcomes. Frequency, duration, and intensity of acute stressors can affect health-related processes. We tested whether the temporal pattern of daily acute stressors (clustered or dispersed across the day) affects depression-related physiology. We used a rodent model to keep stressor frequency, duration, and intensity constant, and experimentally manipulated the temporal pattern of acute stressors delivered during the active phase of the day. Adult male Sprague-Dawley rats were exposed to one of three chronic mild stress groups: Clustered: stressors that occurred within 1 hour of each other (n = 21), Dispersed: stressors that were spread out across the active phase (n = 21), and Control: no stressors presented (n = 21)...
April 12, 2018: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/29648494/placental-glucocorticoid-receptor-and-11%C3%AE-hydroxysteroid-dehydrogenase-2-recruitment-indicates-impact-of-prenatal-adversity-upon-postnatal-development-in-mice
#8
Moshe Gross, Hava Romi, Yelena Gilimovich, Elyashiv Drori, Albert Pinhasov
Prenatal stress may increase concentrations of maternal glucocorticoids, which restrict fetal growth, with variable impact upon postnatal development. Among key regulators of stress hormone effects are the glucocorticoid receptor (GR) and 11β-hydroxysteroid dehydrogenase-2 (11βHSD2), the enzyme that inactivates glucocorticoid. This study utilized mice selectively bred for social dominance (Dom) or submissiveness (Sub), respectively exhibiting resilience or sensitivity to stress, to test whether stress-induced alterations in placental GR and 11βHSD2 protein expression may mediate divergent effects of prenatal adversity upon postnatal development...
April 12, 2018: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/29631452/children-s-biological-responsivity-to-acute-stress-predicts-concurrent-cognitive-performance
#9
Leslie E Roos, Kathryn G Beauchamp, Ryan Giuliano, Maureen Zalewski, Hyoun K Kim, Philip A Fisher
Although prior research has characterized stress system reactivity (i.e. hypothalamic-pituitary-adrenal axis, HPAA; autonomic nervous system, ANS) in children, it has yet to examine the extent to which biological reactivity predicts concurrent goal-directed behavior. Here, we employed a stressor paradigm that allowed concurrent assessment of both stress system reactivity and performance on a speeded-response task to investigate the links between biological reactivity and cognitive function under stress. We further investigated gender as a moderator given previous research suggesting that the ANS may be particularly predictive of behavior in males due to gender differences in socialization...
April 10, 2018: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/29614900/mineralocorticoid-and-glucocorticoid-receptor-mediated-control-of-genomic-responses-to-stress-in-the-brain
#10
Karen R Mifsud, Johannes M H M Reul
Successful coping with stressful events involves adaptive and cognitive processes in the brain that make the individual more resilient to similar stressors in the future. Stressful events result in the secretion of glucocorticoids (GCs) from the adrenal glands into the blood stream. Early work proved instrumental for developing the concept that these hormones act in the brain to coordinate physiological and behavioral responses to stress through binding to two different GC-binding receptors. Once activated these receptors translocate to the nucleus where they act on target genes to facilitate (or sometimes inhibit) transcription...
April 4, 2018: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/29614892/an-evaluation-of-distal-hair-cortisol-concentrations-collected-at-delivery
#11
Olivia R Orta, Shelley S Tworoger, Kathryn L Terry, Brent A Coull, Bizu Gelaye, Clemens Kirschbaum, Sixto E Sanchez, Michelle A Williams
Distal hair segments collected at delivery may allow for the assessment of maternal cortisol secretion in early pregnancy, an important time window for fetal development. Therefore, an investigation of the validity of distal hair cortisol concentrations is warranted. We examined the concordance between proximal and distal hair cortisol concentrations (HCC), both representing the first trimester of pregnancy. The study population was comprised of a random sample of 97 women participating in the Pregnancy Outcomes Maternal and Infant Study, a prospective cohort study of pregnant women attending prenatal clinics in Lima, Peru...
April 4, 2018: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/29607713/association-of-24-h-maternal-deprivation-with-a-saline-injection-in-the-neonatal-period-alters-adult-stress-response-and-brain-monoamines-in-a-sex-dependent-fashion
#12
Rafael Cabbia, Amanda Consoli, Deborah Suchecki
Maternal deprivation (MD) disinhibits the adrenal glands, rendering them responsive to various stressors, including saline injection, and this increased corticosterone (CORT) response can last for as long as 2 h. In the present study, we tested the hypothesis that association of MD on day 11 with a saline injection would alter emotional behavior, CORT response, and brain monoamine levels, in male and female adult rats. Rats were submitted to the novelty suppressed feeding (NSF), the sucrose negative contrast test (SNCT), social investigation test (SIT), and the elevated plus maze (EPM)...
April 1, 2018: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/29577783/chasing-as-a-model-of-psychogenic-stress-characterization-of-physiological-and-behavioral-responses
#13
Ji-Hye Lee, Sunwhi Kimm, Jung-Soo Han, June-Seek Choi
Being chased by a predator or a dominant conspecific can induce significant stress. However, only a limited number of laboratory studies have employed chasing by itself as a stressor. In this study, we developed a novel stress paradigm in which rats were chased by a fast-moving object in an inescapable maze. In Experiment 1, defensive behaviors and stress hormone changes induced by chasing stress were measured. During the chasing stress, the chasing-stress group (n = 9) froze and emitted 22-kHz ultrasonic vocalizations (USVs), but the no-chasing control group (n = 10) did not...
March 25, 2018: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/29557286/affective-and-physiological-response-to-a-novel-parent-adolescent-conflict-stressor
#14
Emily C Cook, Orianna Duncan, Mary Ellen Fernandez, Bryan Mercier, Jason Windrow, Laura R Stroud
Few laboratory paradigms exist that expose adolescents to conflict that might commonly be experienced in parent-adolescent relationships. Given the continued importance of parent-adolescent relationships on adolescent development, as well as the changing expectations in these relationships, we examined the effect of a novel parent-adolescent conflict paradigm on physiological and affective response in a sample of 52 adolescents. The parent-adolescent conflict stressor (PACS) involved adolescent participants (50% girls; M = 14...
March 20, 2018: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/29546791/reduced-levels-of-the-endocannabinoid-arachidonylethanolamide-aea-in-hair-in-patients-with-borderline-personality-disorder-a-pilot-study
#15
Katja Wingenfeld, Lucia Dettenborn, Clemens Kirschbaum, Wei Gao, Christian Otte, Stefan Roepke
Endocannabinoids are involved in depressive and anxious symptoms and might play a role in stress-associated psychiatric disorders. While alterations in the endogenous cannabinoid system have been repeatedly found in patients with posttraumatic stress disorder (PTSD), this system has been mostly neglected in borderline personality disorder (BPD). However, there is first evidence for elevated serum levels of the endocannabinoids arachidonylethanolamide (AEA) and 2-arachidonyl-sn-glycerol (2-AG) in BPD patients compared to healthy controls and PTSD patients...
March 16, 2018: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/29529950/the-plasma-interleukin-6-response-to-acute-psychosocial-stress-in-humans-is-detected-by-a-magnetic-multiplex-assay-comparison-to-high-sensitivity-elisa
#16
Andrea M Quinn, Allison R Williams, Teresa I Sivilli, Charles L Raison, Thaddeus W W Pace
Circulating concentrations of interleukin (IL)-6, an inflammatory biomarker widely assessed in humans to study the inflammatory response to acute psychological stress, have for decades been quantified using enzyme-linked immunosorbent assay (ELISA). However, biobehavioral researchers are increasingly using cytokine multiplex assays instead of ELISA to measure IL-6 and other cytokines. Despite this trend, multiplex assays have not been directly compared to ELISA for their ability to detect subtle stress-induced changes of IL-6...
March 13, 2018: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/29529922/assessing-the-antecedents-and-consequences-of-threat-appraisal-of-an-acute-psychosocial-stressor-the-role-of-optimism-displacement-behavior-and-physiological-responses
#17
Martina Zandara, Carolina Villada, Vanesa Hidalgo, Alicia Salvador
The feeling of stress is increasing in today's societies, particularly in young adults subjected to social evaluative situations in highly competitive academic and work contexts. Threat appraisal is a primary and fundamental reaction when people face a stressful situation. The aim of this study was to investigate the role of dispositional optimism as an antecedent and displacement behavior as a consequence of threat appraisal of a social-evaluative situation of stress. A second objective was to verify the moderating role of physiological responses to stress (heart rate and cortisol reactivity) in the relationship between threat appraisal and displacement behavior...
March 13, 2018: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/29513067/preclinical-stress-research-where-are-we-headed-an-early-career-investigator-s-perspective
#18
Anand Gururajan, Aron Kos, Juan Pablo Lopez
Stress is a major risk factor in the development of various psychiatric disorders such as depression, anxiety and post-traumatic stress disorder. The use of stress paradigms in preclinical contexts is essential to advance our understanding of the pathophysiology of these disorders. However, they are not without their limitations and in this commentary, we have examined some of the practical issues associated with their use. We also highlight some of the latest techniques to identify their neuromolecular correlates as well as the potentially important and integrative role of computational neuroscience...
March 7, 2018: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/29478357/insights-into-thermal-stress-in-japanese-quail-coturnix-coturnix-dynamics-of-immunoendocrine-and-biochemical-responses-during-and-after-chronic-exposure
#19
Franco Nicolas Nazar, Emiliano Ariel Videla, Maria Emilia Fernandez, Maria Carla Labaque, Raul Hector Marin
Avian require comfortable temperatures for optimal development and heat stress is a high concern in warm weather countries. We aimed to assess the dynamics of immunoendocrine and biochemical variables responses of birds exposed to a heat stressor applied during daylight hours, during the chronic stress and the recovery periods. We hypothesize that variables involved in the birds response will be differentially and gradually modified during those periods. Female quail (n = 210) were housed in six rearing boxes...
May 2018: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/29451058/developmental-differences-in-stress-responding-after-repeated-underwater-trauma-exposures-in-rats
#20
Daniel E Altman, Laurence P Simmons, Chau T Vuong, Rachel M Taylor, Jason C Sousa, Sean R Marcsisin, Victor E Zottig, Nicole L T Moore
Adolescence is a distinct developmental period characterized by behavioral and physiological maturation. Rapid ongoing changes during neurodevelopment in particular present potential opportunities for stress to have lasting effects on longitudinal outcomes of behavioral and neuroendocrine function. While adult stress effects on outcomes during adulthood have been characterized, little is known about the lasting effects of adolescent repeated stressor exposure on outcomes during adolescence. We have previously reported different stress responses in adolescent rats relative to adult rats, including a blunted fear response outcome in adulthood in rats stressed during adolescence...
May 2018: Stress: the International Journal on the Biology of Stress
journal
journal
32668
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"