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Stress: the International Journal on the Biology of Stress

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https://www.readbyqxmd.com/read/28166699/planhab-study-assessment-of-psycho-neuroendocrine-function-in-male-subjects-during-21-days-of-normobaric-hypoxia-and-bed-rest
#1
C Strewe, R Zeller, M Feuerecker, M Hoerl, I Kumprej, A Crispin, B Johannes, T Debevec, I Mekjavic, G Schelling, A Choukèr
Immobilization and hypoxemia are conditions often seen in patients suffering from severe heart insufficiency or primary pulmonary diseases (e.g. fibrosis, emphysema). In future planned long-duration and exploration class space missions (including habitats on the moon and Mars), healthy individuals will encounter such a combination of reduced physical activity and oxygen tension by way of technical reasons and the reduced gravitational forces. These overall unconventional extraterrestrial conditions can result in yet unknown consequences for the regulation of stress-permissive, psycho-neuroendocrine responses, which warrant appropriate measures in order to mitigate foreseeable risks...
February 6, 2017: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/28166688/pyrexia-s-effect-on-the-cbg-cortisol-thermocouple-rather-than-cbg-cleavage-elevates-the-acute-free-cortisol-response-to-tnf-alpha-in-humans
#2
Marni Anne Nenke, Signe Tellerup Nielsen, Louise Lang Lehrskov, John Goodwyn Lewis, Wayne Rankin, Kirsten Møller, David James Torpy
Corticosteroid-binding globulin (CBG) cleavage promotes local cortisol delivery in inflammation. Enzymatic cleavage of high-affinity CBG to low affinity CBG (haCBG to laCBG) occurs at inflammatory sites and is now measurable in vivo; however, the time kinetics of haCBG depletion following an inflammatory stimulus is unknown. Hence our aim was to determine the immediate effect of the key pro-inflammatory cytokine TNF-α on CBG levels and cleavage. We performed a crossover study of twelve healthy males receiving a TNF-α vs...
February 6, 2017: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/28152657/obituary
#3
David S Goldstein
No abstract text is available yet for this article.
February 2, 2017: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/28140738/stress-in-childhood-adolescence-and-early-adulthood-and-cortisol-levels-in-older-age
#4
Mathew A Harris, Simon R Cox, Caroline E Brett, Ian J Deary, Alasdair M J MacLullich
The glucocorticoid hypothesis suggests that overexposure to stress may cause permanent upregulation of cortisol. Stress in youth may therefore influence cortisol levels even in older age. Using data from the 6-Day Sample, we investigated the effects of high stress in childhood, adolescence and early adulthood - as well as individual variables contributing to these measures; parental loss, social deprivation, school and home moves, illness, divorce and job instability - upon cortisol levels at age 77 years. Waking, waking+45min (peak) and evening salivary cortisol samples were collected from 159 participants, and the 150 who were not using steroid medications were included in this study...
January 31, 2017: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/28068856/effects-of-ethanol-on-social-avoidance-induced-by-chronic-social-defeat-stress-in-mice
#5
Cristiane A Favoretto, Giovana C Macedo, Isabel M H Quadros
In rodents, chronic social defeat stress promotes deficits in social interest and social interaction. We further explored these antisocial effects by comparing the consequences of two different defeat stress protocols (episodic vs. continuous stress) in a social investigation test. We expected that continuous, but not episodic, stress would induce social deficits in this model. Furthermore, we tested whether a potentially anxiolytic dose of ethanol reverses social deficits induced by defeat stress. Male Swiss mice were exposed to a 10-day social defeat protocol, using daily confrontations with an aggressive resident mouse...
January 31, 2017: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/28124571/the-dsm5-rdoc-debate-on-the-future-of-mental-health-research-implication-for-studies-on-human-stress-and-presentation-of-the-signature-bank
#6
S J Lupien, M Sasseville, N François, C E Giguère, J Boissonneault, P Plusquellec, R Godbout, L Xiong, S Potvin, E Kouassi, A Lesage
In 2008, the National Institute of Mental Health (NIMH) announced that in the next few decades, it will be essential to study the various biological, psychological and social 'signatures' of mental disorders. Along with this new 'signature' approach to mental health disorders, modifications of DSM were introduced. One major modification consisted of incorporating a dimensional approach to mental disorders, which involved analyzing, using a transnosological approach, various factors that are commonly observed across different types of mental disorders...
January 26, 2017: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/28114869/salivary-cortisol-and-cognitive-development-in-infants-from-low-income-communities
#7
Eric D Finegood, Claire Wyman, Thomas G O'Connor, Clancy B Blair
Early stress exposure is proposed to have significant lasting effects on cognitive development. The glucocorticoid hormone cortisol, a product of the hypothalamic-pituitary-adrenal (HPA) axis, is a particular focus of research, however, the majority of past research has been based on studies of older children and adults. Evidence linking cortisol levels in infancy with cognitive development is lacking. In a large cohort sample of infants (N = 1,091) oversampled for psychosocial risk, we tested whether basal cortisol levels and cortisol reactivity to emotional stressors administered at 7 and 15 months of age were associated with cognitive development measured at 15 months...
January 23, 2017: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/28114849/better-executive-function-under-stress-mitigates-the-effects-of-recent-life-stress-exposure-on-health-in-young-adults
#8
Grant S Shields, Wesley G Moons, George M Slavich
Executive function is a neuropsychological construct that enables controlled cognitive processing, which has been hypothesized to enhance individuals' resilience to stress. However, little empirical work has directly examined how executive function under different conditions mitigates the negative effects of stress exposure on health. To address this issue, we recruited 110 healthy young adults and assessed their recent life stress exposure, executive function in either a stressful or non-stressful context, and current health complaints...
January 23, 2017: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/28027684/associations-between-circadian-and-stress-response-cortisol-in-children
#9
Sterre S H Simons, Antonius H N Cillessen, Carolina de Weerth
Hypothalamic-pituitary-adrenal (HPA) axis functioning is characterized by the baseline production of cortisol following a circadian rhythm, as well as by the superimposed production of cortisol in response to a stressor. However, it is relatively unknown whether the basal cortisol circadian rhythm is associated with the cortisol stress response in children. Since alterations in cortisol stress responses have been associated with mental and physical health, this study investigated whether the cortisol circadian rhythm is associated with cortisol stress responses in 6-year-old children...
December 27, 2016: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/28027673/non-invasive-assessment-of-altered-activity-following-restraint-in-mice-using-an-automated-physiological-monitoring-system
#10
Jereme G Spiers, Hsiao-Jou Cortina Chen, Frederik J Steyn, Nickolas A Lavidis, Trent M Woodruff, John D Lee
In the laboratory setting, typical endocrine and targeted behavioral tests are limited in their ability to provide a direct assessment of stress in animals housed in undisturbed conditions. We hypothesized that an automated phenotyping system would allow the detection of subtle stress-related behavioral changes well beyond the time-frames examined using conventional methods. In the present study, we have utilized the TSE PhenoMaster system to continuously record basal behaviors and physiological parameters including activity, body weight, food intake, and oxygen consumption in undisturbed and stressed C57Bl/6J male mice (n = 12/group), with a pharmacological intervention using the conventional anxiolytic, diazepam (5 mg kg(-1) i...
December 27, 2016: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/27892761/autonomic-markers-associated-with-generalized-social-phobia-symptoms-heart-rate-variability-and-salivary-alpha-amylase
#11
María J García-Rubio, Laura Espín, Vanesa Hidalgo, Alicia Salvador, Jesús Gómez-Amor
The study of autonomic nervous system changes associated with generalized social phobia (GSP) disorder has increased in recent years, showing contradictory results. The present study aimed to evaluate how young people with GSP reacted before, during, and after exposure to the Trier Stress Social Test (TSST), focusing on their autonomic changes (heart rate variability (HRV) and salivary alpha-amylase (sAA)) compared to a control group (non-GSP). Some psychological variables were also considered. Sex was specifically studied as a possible modulator of autonomic fluctuations and psychological state...
December 21, 2016: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/27923288/toll-like-receptor-4-protects-against-stress-induced-ulcers-via-regulation-of-glucocorticoid-production-in-mice
#12
Liang Wang, Pengfei Luo, Fang Zhang, Yuelu Zhang, Xingtong Wang, Fei Chang, Yuechan Zhang, Hongtai Tang, Zhaofan Xia
Stress-induced gastric ulcer is an important life-threatening condition, while the molecular basis of its development is incompletely understood. Toll-like receptor 4 (TLR4), an innate immune pattern recognition receptor, can induce pro-inflammatory transcription, aggravating a stress ulcer. The present study found that TLR4 played a protective role in a mouse model of water immersion (23 °C) restraint stress. Wild-type (WT) and TLR4(-/-) male mice were respectively divided into five groups (5 per group), and exposed to the stressor for 0, 0...
December 6, 2016: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/27873537/brain-region-specific-effects-of-immobilization-stress-on-cholinesterases-in-mice
#13
Paulina Valuskova, Vladimir Farar, Katerina Janisova, Katarina Ondicova, Boris Mravec, Richard Kvetnansky, Jaromir Myslivecek
Brain acetylcholinesterase (AChE) variant AChER expression increases with acute stress, and this persists for an extended period, although the timing, strain and laterality differences, have not been explored previously. Acute stress transiently increases acetylcholine release, which in turn may increase activity of cholinesterases. Also the AChE gene contains a glucocorticoid response element (GRE), and stress-inducible AChE transcription and activity changes are linked to increased glucocorticoid levels. Corticotropin-releasing hormone knockout (CRH-KO) mice have basal glucocorticoid levels similar to wild type (WT) mice, but much lower levels during stress...
December 6, 2016: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/27841087/dispositional-self-control-relationships-with-aerobic-capacity-and-morning-surge-in-blood-pressure
#14
Ross W May, Gregory S Seibert, Marcos A Sanchez-Gonzalez, Michael C Fitzgerald, Frank D Fincham
The psychological, behavioral and psychosocial implications of self-control are well established, but relatively little is known about its implications for physical health. This study examined the association between self-control and two important indicators of cardiovascular risk: morning blood pressure surge (MBPS) and maximum oxygen consumption (VO2max). Undergraduate students (N = 78) completed a measure of dispositional self-control (Brief Self-Control Scale), participated in a 24-h ambulatory assessment of heart rate (HR) and blood pressure (BP), and completed the YMCA Cycle Ergometer Submaximal Test...
November 30, 2016: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/27820975/rigid-patterns-of-effortful-choice-behavior-after-acute-stress-in-rats
#15
Evan E Hart, Alexandra Stolyarova, Michael A Conoscenti, Thomas R Minor, Alicia Izquierdo
Physical effort is a common cost of acquiring rewards, and decreased effort is a feature of many neuropsychiatric disorders. Stress affects performance on several tests of cognition and decision-making in both humans and nonhumans. Only a few recent reports show impairing effects of stress in operant tasks involving effort and cognitive flexibility. Brain regions affected by stress such as the medial prefrontal cortex and amygdala are also implicated in mediating effortful choices. Here we assessed effort-based decision-making after an acute stress procedure known to induce persistent impairment in shuttle escape and elevated plasma corticosterone...
November 8, 2016: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/27594113/beyond-symptom-self-report-use-of-a-computer-avatar-to-assess-post-traumatic-stress-disorder-ptsd-symptoms
#16
Catherine E Myers, Milen L Radell, Christine Shind, Yasheca Ebanks-Williams, Kevin D Beck, Mark W Gilbertson
Post-traumatic stress disorder (PTSD) can occur in the wake of exposure to a traumatic event. Currently, PTSD symptoms are assessed mainly through self-report in the form of questionnaire or clinical interview. Self-report has inherent limitations, particularly in psychiatric populations who may have limited awareness of deficit, reduced attention span, or poor vocabulary and/or literacy skills. Diagnosis and evaluation of treatment efficacy would be aided by behavioral measures. A viable alternative may be virtual environments, in which the participant guides an on-screen "avatar" through a series of onscreen events meant to simulate real-world situations...
November 2016: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/27588343/impact-of-acute-psychological-stress-on-cardiovascular-risk-factors-in-face-of-insulin-resistance
#17
Kristian T Jones, Richard C Shelton, Jun Wan, Li Li
Individuals with insulin resistance (IR) are at greater risk for cardiovascular disease (CVD). Psychological stress may contribute to develop CVD in IR, although mechanisms are poorly understood. Our aim was to test the hypothesis that individuals with IR have enhanced emotional and physiological responses to acute psychological stress, leading to increased CVD risk. Sixty participants were enrolled into the study, and classified into IR group (n = 31) and insulin sensitive group (n = 29) according to the Quantitative insulin sensitivity check index, which was calculated based on an oral glucose tolerance test...
November 2016: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/27556727/the-influence-of-maternal-care-and-overprotection-on-youth-adrenocortical-stress-response-a-multiphase-growth-curve-analysis
#18
Chrystal Vergara-Lopez, Stephenie Chaudoir, Margaret Bublitz, Maggie O'Reilly Treter, Laura Stroud
We examined the association between two dimensions of maternal parenting style (care and overprotection) and cortisol response to an acute laboratory-induced stressor in healthy youth. Forty-three participants completed the Parental Bonding Instrument and an adapted version of the Trier Social Stress Test-Child (TSST-C). Nine cortisol samples were collected to investigate heterogeneity in different phases of youth's stress response. Multiphase growth-curve modeling was utilized to create latent factors corresponding to individual differences in cortisol during baseline, reactivity, and recovery to the TSST-C...
November 2016: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/27788633/light-and-water-are-not-simple-conditions-fine-tuning-of-animal-housing-in-male-c57bl-6-mice
#19
Dominik Langgartner, Sandra Foertsch, Andrea M Füchsl, Stefan O Reber
While animal housing conditions are highly controlled and standardized between different laboratories, there are still many subtle differences that unavoidably influence the host organisms and, consequently, inter-laboratory reproducibility. Here, we investigated the physiological and immunological consequences between two light-dark cycle (LDC) lengths (14h/10h versus 12h/12h LDC) and two commonly used forms of drinking water (acidified drinking water (AW) versus normal tap water (NW)) in single-housed (SH) mice...
October 27, 2016: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/27696924/the-rna-editing-deaminase-adar-is-involved-in-stress-resistance-of-artemia-diapause-embryos
#20
Li Dai, Xue-Chen Liu, Sen Ye, Hua-Wei Li, Dian-Fu Chen, Xiao-Jian Yu, Xue-Ting Huang, Li Zhang, Fan Yang, Jin-Shu Yang, Wei-Jun Yang
The most widespread type of RNA editing, conversion of adenosine to inosine (A→I), is catalyzed by two members of the adenosine deaminase acting on RNA (ADAR) family, ADAR1 and ADAR2. These enzymes edit transcripts for neurotransmitter receptors and ion channels during adaption to changes in the physical environment. In the primitive crustacean Artemia, when maternal adults are exposed to unfavorable conditions, they release diapause embryos to withstand harsh environments. The aim of the current study was therefore to elucidate the role of ADAR of Artemia diapause embryos in resistance to stress...
October 4, 2016: Stress: the International Journal on the Biology of Stress
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