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Respirology: Official Journal of the Asian Pacific Society of Respirology

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https://www.readbyqxmd.com/read/28211210/asthma-or-asthma-copd-overlap-syndrome
#1
LETTER
Fa-Ping Wang, Ting Liu, Geng Wang, Hui Mao
No abstract text is available yet for this article.
February 16, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28211152/asthma-or-asthma-copd-overlap-syndrome-reply
#2
LETTER
Tunn R Tay, Naghmeh Radhakrishna, Mark Hew
No abstract text is available yet for this article.
February 16, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28206696/medullary-neuropathology-in-sleep-apnoea
#3
LETTER
J Howard Jaster
No abstract text is available yet for this article.
February 16, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28206691/new-biomarkers-in-community-acquired-pneumonia-another-step-in-improving-outcome-prediction
#4
EDITORIAL
Paola Faverio, Oriol Sibila
No abstract text is available yet for this article.
February 16, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28198129/beyond-the-thermistor-novel-technology-for-the-ambulatory-diagnosis-of-obstructive-sleep-apnoea
#5
EDITORIAL
Emma L Gray, David J Barnes
No abstract text is available yet for this article.
February 14, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28198072/ager-gene-polymorphisms-and-soluble-receptor-for-advanced-glycation-end-product-in-patients-with-idiopathic-pulmonary-fibrosis
#6
Kakuhiro Yamaguchi, Hiroshi Iwamoto, Yasushi Horimasu, Shinichiro Ohshimo, Kazunori Fujitaka, Hironobu Hamada, Witold Mazur, Nobuoki Kohno, Noboru Hattori
BACKGROUND AND OBJECTIVE: The receptor for advanced glycation end product (RAGE) is a multiligand cell-surface receptor abundantly expressed in the lung. RAGE/ligand interaction has been postulated to participate in the pathogenesis of inflammatory diseases, while soluble RAGE (sRAGE) might act as a decoy receptor. A functional polymorphism rs2070600 in the gene coding RAGE (AGER) might modulate its receptor function. The aim of this study was to investigate the association of AGER polymorphisms and circulatory sRAGE with the development and progression of idiopathic pulmonary fibrosis (IPF)...
February 14, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28177181/radial-endobronchial-ultrasound-for-the-diagnosis-of-peripheral-pulmonary-lesions-a-systematic-review-and-meta-analysis
#7
REVIEW
Muhammad S Ali, William Trick, Benjamin I Mba, Divyanshu Mohananey, Jaskaran Sethi, Ali I Musani
Tissue diagnosis of peripheral pulmonary lesions (PPLs) can be challenging. In the past, flexible bronchoscopy was commonly performed for this purpose but its diagnostic yield is suboptimal. This has led to the development of new bronchoscopic modalities such as radial endobronchial ultrasound (R-EBUS), electromagnetic navigation bronchoscopy (ENB) and virtual bronchoscopy (VB). We performed this meta-analysis using data from previously published R-EBUS studies, to determine its diagnostic yield and other performance characteristics...
February 8, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28166611/health-related-quality-of-life-in-idiopathic-pulmonary-fibrosis-data-from-the-australian-ipf-registry
#8
Ian N Glaspole, Sally A Chapman, Wendy A Cooper, Samantha J Ellis, Nicole S Goh, Peter M Hopkins, Sacha Macansh, Annabelle Mahar, Yuben P Moodley, Eldho Paul, Paul N Reynolds, E Haydn Walters, Christopher J Zappala, Tamera J Corte
BACKGROUND AND OBJECTIVE: Studies analysing the effect of worsening pulmonary physiological impairment in idiopathic pulmonary fibrosis (IPF) with respect to quality of life have been limited to single centres or highly selected trial populations. The aim of this study was to determine the principal determinants of baseline and longitudinal health-related quality of life (HRQoL) in a large unselected IPF population. METHODS: We used the Australian IPF Registry to examine the relationship between HRQoL, measured using the St George Respiratory Questionnaire (SGRQ), and demographic features, physiological features, co-morbidities and symptoms...
February 6, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28166610/oral-administration-of-saccharomyces-cerevisiae-ufmg-a-905-prevents-allergic-asthma-in-mice
#9
Vanessa M B Fonseca, Thamires M S Milani, Rafael Prado, Vania L D Bonato, Simone G Ramos, Flaviano S Martins, Elcio O Vianna, Marcos de C Borges
BACKGROUND AND OBJECTIVE: The prevalence of asthma has increased in communities that adopt a Western lifestyle and become more urbanized. Probiotics may be effective in the prevention of allergic diseases, such as asthma. The aim of the current study was to examine the effects of Saccharomyces cerevisiae UFMG A-905 in an allergic model of asthma. METHODS: Balb/c mice were sensitized twice with ovalbumin (OVA) intraperitoneally, 1 week apart and challenged with OVA intranasally for 3 days...
February 6, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28161892/osa-and-cardiometabolic-risk-what-s-the-bottom-line
#10
REVIEW
Camilla M Hoyos, Luciano F Drager, Sanjay R Patel
Obstructive sleep apnoea (OSA) is a common condition characterized by repetitive upper airway obstruction during sleep. OSA promotes wide intrathoracic pressure swings, intermittent hypoxia and sleep fragmentation. Growing evidence derived from animal models mimicking the oxygen profile observed in patients with OSA as well as clinical studies support that this important sleep-disordered breathing is associated with increased cardiovascular risk. Although the precise mechanisms are not fully established, it is conceivable that the metabolic deregulation promoted by the components of OSA may have an important causal role in the poor cardiovascular prognosis...
February 5, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28161888/the-cost-of-asthma-control
#11
EDITORIAL
Sanjay H Chotirmall
No abstract text is available yet for this article.
February 5, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28150362/global-strategy-for-the-diagnosis-management-and-prevention-of-chronic-obstructive-lung-disease-2017-report
#12
Claus F Vogelmeier, Gerard J Criner, Fernando J Martinez, Antonio Anzueto, Peter J Barnes, Jean Bourbeau, Bartolome R Celli, Rongchang Chen, Marc Decramer, Leonardo M Fabbri, Peter Frith, David M G Halpin, M Victorina López Varela, Masaharu Nishimura, Nicolas Roche, Roberto Rodriguez-Roisin, Don D Sin, Dave Singh, Robert Stockley, Jørgen Vestbo, Jadwiga A Wedzicha, Alvar Agusti
This Executive Summary of the Global Strategy for the Diagnosis, Management, and Prevention of COPD (GOLD) 2017 Report focuses primarily on the revised and novel parts of the document. The most significant changes include: i) the assessment of COPD has been refined to separate the spirometric assessment from symptom evaluation. ABCD groups are now proposed to be derived exclusively from patient symptoms and their history of exacerbations; ii) for each of the groups A to D, escalation strategies for pharmacological treatments are proposed; iii) the concept of de-escalation of therapy is introduced in the treatment assessment scheme; iv) nonpharmacologic therapies are comprehensively presented and; v) the importance of comorbid conditions in managing COPD is reviewed...
February 2, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28139873/impact-of-exacerbations-on-adherence-and-outcomes-of-pulmonary-rehabilitation-in-patients-with-copd
#13
Dionne C W Braeken, Martijn A Spruit, Sarah Houben-Wilke, Dionne E Smid, Gernot G U Rohde, Emiel F M Wouters, Frits M E Franssen
BACKGROUND AND OBJECTIVE: Dropout or lack of response is an important issue in pulmonary rehabilitation (PR), which underlines the need to identify predictors of dropout and response. Acute exacerbations (AEs) of COPD may influence dropout rates and PR response. We aimed to assess differences in dropout and outcomes of PR between COPD with and without AEs. METHODS: Clinically stable patients with moderate-to-very severe COPD (age: 64.1 ± 9.1 years, 55.6% males, forced expiratory volume in 1 s (FEV1 ): 48...
January 31, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28139869/effect-of-pulmonary-tuberculosis-on-clinical-outcomes-of-long-term-dialysis-patients-pre-and-post-dots-implementation-in-taiwan
#14
Kuan-Jen Bai, Kuan-Chih Huang, Chih-Hsin Lee, Chao-Hsiun Tang, Ming-Chih Yu, Yuh-Mou Sue
BACKGROUND AND OBJECTIVE: The link between tuberculosis (TB) and dialysis is known; however, the impact of TB on the clinical outcomes remains to be elucidated. This study aims to determine the clinical consequences of pulmonary TB among patients under long-term dialysis. METHODS: A retrospective propensity-scores matched (1:4) cohort study was conducted by retrieving patient data for pulmonary TB after long-term dialysis commencement from the Taiwan National Health Insurance Research Database between 1999 and 2013...
January 31, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28139858/geographic-and-socioeconomic-factors-in-patients-with-malignant-pleural-mesothelioma-in-new-south-wales-and-their-impact-upon-clinical-outcomes
#15
Anthony Linton, Matthew Soeberg, Richard Broome, Steven Kao, Nico van Zandwijk
BACKGROUND AND OBJECTIVE: Whilst the impact of clinicopathological factors on the prognosis of malignant pleural mesothelioma (MPM) is well understood, socioeconomic and geographic factors have received less attention. We analysed the relationship between geographic and socioeconomic factors upon survival and treatment provision in a large series of patients with MPM. METHODS: We assessed MPM patients awarded compensation between 2002 and 2009 with additional MPM incidence data from the New South Wales (NSW) Cancer Registry...
January 31, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28139852/eosinophil-transendothelial-migration-induced-by-the-bronchoalveolar-lavage-fluid-of-acute-eosinophilic-pneumonia
#16
Kazuyuki Nakagome, Hisakazu Shoda, Tetsu Shirai, Fuyumi Nishihara, Tomoyuki Soma, Yoshitaka Uchida, Yoshio Sakamoto, Makoto Nagata
BACKGROUND AND OBJECTIVE: Acute eosinophilic pneumonia (AEP) is characterized by a massive pulmonary infiltration of eosinophils. Mechanisms regulating the selective accumulation of eosinophils in AEP have not been fully established. The objective of this study was to evaluate the mechanisms of eosinophil accumulation in alveolar spaces through examination of bronchoalveolar lavage fluid (BALF) from AEP patients (AEP-BALF). METHODS: Eosinophils were isolated from the blood of healthy subjects and were placed on a human pulmonary microvascular endothelial cell monolayer cultured on Transwell filters (Coster, Cambridge, MA, USA)...
January 31, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28122397/oral-administration-of-clostridium-butyricum-cgmcc0313-1-reduces-ovalbumin-induced-allergic-airway-inflammation-in-mice
#17
Zhang Juan, Shi Zhao-Ling, Zeng Ming-Hua, Wei Chun, Wu Hai-Xia, Liu Meng-Yun, Huang Jian-Qiong, Zheng Yue-Jie, Sun Xin
BACKGROUND AND OBJECTIVE: Probiotic bacteria can induce immune regulation or immune tolerance in patients with allergic diseases, but the underlying mechanisms are still unclear. There has been a growing interest in the use of beneficial bacteria for allergic diseases recently. This study aimed at exploring whether Clostridium butyricum CGMCC0313-1 (C. butyricum) can reduce ovalbumin (OVA)-induced allergic airway inflammation in a mouse model. METHODS: Mouse model of allergic airway inflammation induced via OVA was used in this study...
January 25, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28120412/rare-variant-of-map2k7-is-associated-with-increased-risk-of-copd-in-southern-and-eastern-chinese
#18
Fuman Qiu, Yinyan Li, Xiaoxiao Lu, Chenli Xie, Qingqing Nong, Di Wu, Jiansong Chen, Lei Yang, Yifeng Zhou, Jiachun Lu
BACKGROUND AND OBJECTIVE: A wide range of common loci have been extensively screened and evaluated for their associations with various complex diseases; however, the relevance of rare variants causing missense substitutions in the protein-coding genes in human diseases is still poorly understood. METHODS: In this study, we conducted a two-stage retrospective study of a total of 1791 patients with COPD and 1940 controls in southern and eastern Chinese to test relevancies of five rare variants (i...
January 24, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28117553/airflow-limitation-severity-and-post-operative-pulmonary-complications-following-extra-pulmonary-surgery-in-copd-patients
#19
Beomsu Shin, Hyun Lee, Danbee Kang, Byeong-Ho Jeong, Hyung Koo Kang, Hae Ri Chon, Won-Jung Koh, Man Pyo Chung, Eliseo Guallar, Juhee Cho, Hye Yun Park
BACKGROUND AND OBJECTIVE: The association between airflow limitation severity and post-operative pulmonary complications (PPCs) among COPD patients undergoing extra-pulmonary surgery is unknown. We evaluated the association between forced expiratory volume in 1 s (FEV1 ) and PPC in COPD patients undergoing extra-pulmonary surgery. METHODS: Using prospective cohort of PPC evaluation for extra-pulmonary surgery, we identified 694 COPD patients who conducted PPC evaluation before extra-pulmonary surgery between March 2014 and January 2015 at a tertiary hospital, Seoul, Korea...
January 24, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28117530/progression-of-mean-pulmonary-arterial-pressure-in-idiopathic-pulmonary-fibrosis-with-mild-to-moderate-restriction
#20
Ryo Teramachi, Hiroyuki Taniguchi, Yasuhiro Kondoh, Masahiko Ando, Tomoki Kimura, Kensuke Kataoka, Atsushi Suzuki, Taiki Furukawa, Koji Sakamoto, Yoshinori Hasegawa
BACKGROUND AND OBJECTIVE: Elevation of mean pulmonary arterial pressure (MPAP) is associated with poor prognosis in patients with idiopathic pulmonary fibrosis (IPF), yet the progression of MPAP in patients with IPF has not been sufficiently elucidated. We evaluated serial changes in MPAP and its determinants in patients with IPF with mild to moderate restriction. METHODS: We retrospectively reviewed patients with IPF who underwent initial evaluations including right heart catheterization (RHC) in our institute from May 2007 to December 2013 with follow-up RHC at least 1 year later...
January 24, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
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