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Respirology: Official Journal of the Asian Pacific Society of Respirology

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https://www.readbyqxmd.com/read/30408846/in-search-of-a-good-fit-cpap-therapy-mask-selection-for-obstructive-sleep-apnoea
#1
EDITORIAL
Peter A Cistulli, Colin E Sullivan
No abstract text is available yet for this article.
November 8, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/30408263/respiratory-adjuncts-to-niv-in-neuromuscular-disease
#2
REVIEW
Nicole Sheers, Mark E Howard, David J Berlowitz
Muscle weakness is an intrinsic feature of neuromuscular diseases (NMD). When the respiratory muscles are involved, the ability to take a deep breath is compromised, leading to reduced lung volumes and a restrictive ventilatory impairment. Inspiratory, expiratory and bulbar muscle weakness can also impair cough, which may impede secretion clearance. Non-invasive ventilation (NIV) is an established and indispensable therapy to manage hypoventilation and respiratory failure. The role of other therapies that support respiratory health is less clearly defined, and the evidence of efficacy is also harder to summarize as the underlying data are of a lesser quality...
November 8, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/30406954/non-invasive-ventilation-or-high-flow-oxygen-therapy-when-to-choose-one-over-the-other
#3
REVIEW
Jean-Pierre Frat, Rémi Coudroy, Arnaud W Thille
It has been found that high-flow oxygen therapy (HFOT) can reduce mortality of patients admitted to intensive care unit (ICU) for de novo acute respiratory failure (ARF) as compared to non-invasive ventilation (NIV). HFOT might therefore be considered as a first-line strategy of oxygenation in these patients. The beneficial effects of HFOT may be explained by its good tolerance and by physiological characteristics including delivery of high FiO2 , positive end expiratory pressure (PEEP) effect and continuous dead space washout contributing to decreased work of breathing...
November 8, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/30406950/pulmonary-arterial-hypertension-in-asia-as-elsewhere-still-a-lethal-disease-despite-modern-treatment
#4
EDITORIAL
Paul N Reynolds
No abstract text is available yet for this article.
November 8, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/30384396/physical-activity-associates-with-disease-characteristics-of-severe-asthma-bronchiectasis-and-copd
#5
Laura Cordova-Rivera, Peter G Gibson, Paul A Gardiner, Vanessa M McDonald
BACKGROUND AND OBJECTIVE: Physical activity (PA) in obstructive airway diseases (OAD) is likely to be impaired but this has not been extensively studied outside of chronic obstructive pulmonary disease (COPD). We describe PA levels in severe asthma and bronchiectasis compared to moderate-severe COPD and to controls, and tested the cross-sectional associations of PA (steps/day) with shared disease characteristics in the OAD group. METHODS: Adults with OAD (severe asthma = 62, COPD = 67, bronchiectasis = 60) and controls (n = 63) underwent a multidimensional assessment, including device-measured PA levels...
November 1, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/30338882/applying-new-tools-to-control-tuberculosis
#6
REVIEW
Chi Chiu Leung, Cynthia B E Chee, Ying Zhang
No abstract text is available yet for this article.
October 19, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/30338880/clinical-utility-of-pulmonary-function-and-blood-biomarker-measurements
#7
EDITORIAL
Ross Vlahos
No abstract text is available yet for this article.
October 19, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/30332712/a-letter-from-o-canada
#8
LETTER
Don D Sin, R Robert Schellenberg
No abstract text is available yet for this article.
October 17, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/30328644/implications-of-the-diagnostic-criteria-of-idiopathic-pulmonary-fibrosis-in-clinical-practice-analysis-from-the-australian-idiopathic-pulmonary-fibrosis-registry
#9
Helen E Jo, Ian Glaspole, Nicole Goh, Peter M A Hopkins, Yuben Moodley, Paul N Reynolds, Sally Chapman, Eugene Haydn Walters, Christopher Zappala, Heather Allan, Sacha Macansh, Christopher Grainge, Gregory J Keir, Andrew Hayen, Douglas Henderson, Sonja Klebe, Stefan B Heinze, Anne Miller, Hannah C Rouse, Edwina Duhig, Wendy A Cooper, Annabelle M Mahar, Samantha Ellis, Samuel R McCormack, Bernard Ng, David B Godbolt, Tamera J Corte
BACKGROUND AND OBJECTIVE: Current guidelines for the diagnosis of idiopathic pulmonary fibrosis (IPF) provide specific criteria for diagnosis in the setting of multidisciplinary discussion (MDD). We evaluate the utility and reproducibility of these diagnostic guidelines, using clinical data from the Australian IPF Registry. METHODS: All patients enrolled in the registry undergo a diagnostic review whereby international IPF guidelines are applied via a registry MDD...
October 17, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/30324714/towards-a-refined-definition-of-combined-pulmonary-fibrosis-and-emphysema
#10
EDITORIAL
Jeffrey J Swigris
No abstract text is available yet for this article.
October 15, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/30324712/predicting-response-to-bronchial-thermoplasty-in-patients-with-severe-uncontrolled-asthma-an-elusive-goal
#11
EDITORIAL
Chase S Hall, Mario Castro
No abstract text is available yet for this article.
October 15, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/30320420/predictive-factors-and-prognostic-effect-of-telomere-shortening-in-pulmonary-fibrosis
#12
Lurdes Planas-Cerezales, Elena G Arias-Salgado, Ivette Buendia-Roldán, Ana Montes-Worboys, Cristina Esquinas López, Vanesa Vicens-Zygmunt, Patricio Luburich Hernaiz, Roger Llatjós Sanuy, Virginia Leiro-Fernandez, Eva Balcells Vilarnau, Ernest Sala Llinás, Jordi Dorca Sargatal, Rosario Perona Abellón, Moisés Selman, Maria Molina-Molina
BACKGROUND AND OBJECTIVE: The abnormal shortening of telomeres is a mechanism linking ageing to idiopathic pulmonary fibrosis (IPF) that could be useful in the clinical setting. The objective of this study was to identify the IPF patients with higher risk for telomere shortening and to investigate the outcome implications. METHODS: Consecutive Spanish patients were included at diagnosis and followed up for 3 years. DNA blood samples from a Mexican cohort were used to validate the results found in Spanish sporadic IPF...
October 15, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/30315609/double-combination-inhalers-in-copd-how-to-get-your-head-around-this-data
#13
EDITORIAL
Dave Singh
No abstract text is available yet for this article.
October 12, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/30295360/targeting-reactive-oxygen-species-for-respiratory-infection-fact-or-fancy
#14
REVIEW
Stavros Selemidis
No abstract text is available yet for this article.
October 8, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/30284760/modelling-copd-co-morbidities-in-preclinical-models
#15
REVIEW
Ross Vlahos, Steven Bozinovski
No abstract text is available yet for this article.
October 4, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/30284753/tgf-%C3%AE-master-regulator-of-inflammation-and-fibrosis
#16
REVIEW
Alastair G Stewart, Belinda Thomas, Jon Koff
No abstract text is available yet for this article.
October 4, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/30284745/a-consensus-opinion-amongst-stakeholders-as-to-benefits-of-obstructive-sleep-apnoea-treatment-for-cardiovascular-health
#17
Shane A Landry, Siobhan Banks, Peter A Cistulli, Garun S Hamilton, Laure Héraud, Kristina Kairaitis, Steven Lubke, Sutapa Mukherjee, Teanau Roebuck, Joesph Soda, Darren Umbers, Shantha M W Rajaratnam, Darren Mansfield
BACKGROUND AND OBJECTIVE: Obstructive sleep apnoea (OSA) is a prevalent sleep disorder associated with increased cardiovascular morbidity and mortality. Whether treatment of OSA improves cardiovascular risk remains controversial. Our aim was to determine a consensus opinion of key sleep medicine stakeholder groups as to the cardiovascular benefits of treating moderate-severe OSA. METHODS: A multidisciplinary panel was assembled from representatives from the Australasian Sleep Association, Sleep Health Foundation, Australasian Sleep Technologists Association, the Sleep Health Foundation Business Council and the Sleep Disorders Australia patient support group...
October 4, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/30282116/the-contribution-of-respiratory-microbiome-analysis-to-a-treatable-traits-model-of-care
#18
REVIEW
Steven L Taylor, Hannah E O'Farrell, Jodie L Simpson, Ian A Yang, Geraint B Rogers
The composition of the airway microbiome in patients with chronic airway diseases, such as severe asthma, chronic obstructive pulmonary disease (COPD), bronchiectasis and cystic fibrosis (CF), has the potential to inform a precision model of clinical care. Patients with these conditions share overlapping disease characteristics, including airway inflammation and airflow limitation. The clinical management of chronic respiratory conditions is increasingly moving away from a one-size-fits-all model based on primary diagnosis, towards care targeting individual disease traits, and is particularly useful for subgroups of patients who respond poorly to conventional therapies...
October 3, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/30282111/understanding-the-patient-s-experience-of-care-in-idiopathic-pulmonary-fibrosis
#19
Kimberley Burnett, Ian Glaspole, Anne E Holland
No abstract text is available yet for this article.
October 3, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/30264869/transcriptomics-and-single-cell-rna-sequencing
#20
REVIEW
Daniel C Chambers, Alan M Carew, Samuel W Lukowski, Joseph E Powell
The past four decades have yielded advances in molecular biology allowing detailed characterization of the cellular genome and the transcriptome: the complete set of RNA species transcribed by a cell or tissue. Through transcriptomics and next-generation sequencing, we can now attain an unprecedented level of detail in understanding cellular phenotypes through examining the genes expressed in specific physiological and pathological states. In this review, we provide an overview of transcriptomics and RNA-sequencing in the analysis of whole tissue and single cells...
September 28, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
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