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Respirology: Official Journal of the Asian Pacific Society of Respirology

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https://www.readbyqxmd.com/read/28445925/endobronchial-ultrasound-elastography-for-the-differentiation-of-benign-and-malignant-lymph-nodes
#1
LETTER
Saurabh Mittal, Anant Mohan, Karan Madan
No abstract text is available yet for this article.
April 26, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28445920/endobronchial-ultrasound-elastography-for-the-differentiation-of-benign-and-malignant-lymph-nodes-reply
#2
LETTER
Potjanee Korrungruang, Viboon Boonsarngsuk
No abstract text is available yet for this article.
April 26, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28440565/lower-limb-muscle-function-and-exercise-performance-in-lung-cancer
#3
EDITORIAL
Matthew Maddocks, Catherine Granger
No abstract text is available yet for this article.
April 25, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28440556/direct-hemoperfusion-with-polymyxin-b-immobilized-fibre-treatment-for-acute-exacerbation-of-interstitial-pneumonia
#4
Haruhiko Furusawa, Makiko Sugiura, Chieko Mitaka, Naohiko Inase
BACKGROUND AND OBJECTIVE: Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) is recognized as an important cause of mortality. AE has also been reported in patients with other interstitial lung diseases such as idiopathic non-specific interstitial pneumonia (NSIP) and interstitial pneumonia associated with collagen vascular disease (CVD). Current therapies such as high-dose corticosteroid with immunosuppressive agents have provided little benefit for AE. Direct hemoperfusion (DHP) with a polymyxin B-immobilized fibre column (PMX) was originally developed for the treatment of endotoxaemia...
April 25, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28440554/tolerability-of-treatment-with-pirfenidone-or-nintedanib-for-pulmonary-fibrosis-in-the-real-world
#5
EDITORIAL
Takashi Ogura, Hideya Kitamura
No abstract text is available yet for this article.
April 25, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28440553/different-location-same-results
#6
EDITORIAL
Kyle R Brownback
No abstract text is available yet for this article.
April 25, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28429504/induced-pluripotent-stem-cells-reduce-neutrophil-chemotaxis-via-activating-grk2-in-endotoxin-induced-acute-lung-injury
#7
Vincent Yi-Fong Su, Shih-Hwa Chiou, Chi-Shiuan Lin, Wei-Chih Chen, Wen-Kuang Yu, Yen-Wen Chen, Cheng-Yu Chen, Kuang-Yao Yang
BACKGROUND AND OBJECTIVE: We investigated the effect of induced pluripotent stem cells (iPSCs) in moderating neutrophil chemotaxis in endotoxin-induced acute lung injury (ALI). METHODS: Male C57BL/6 mice at 8-12 weeks of age were studied. Murine iPSCs were delivered through the tail veins of mice 4 h after intratracheal instillation of endotoxin. Lung histopathological findings, neutrophil counts in peripheral blood and bronchoalveolar lavage fluid (BALF), bone marrow (BM) cell distribution, expression of chemokine receptors and regulatory signalling pathways were analysed after 24 h...
April 21, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28422346/does-limb-partitioning-and-positioning-affect-acute-cardiorespiratory-responses-during-strength-exercises-in-patients-with-copd
#8
Priscila Robles, Tamara Araujo, Dina Brooks, Karl Zabjek, Tania Janaudis-Ferreira, Susan Marzolini, Roger Goldstein, Sunita Mathur
BACKGROUND AND OBJECTIVE: Cardiorespiratory responses and symptoms in response to endurance exercise in patients with COPD vary with the number and position of involved limbs. Responses to such variations have never been quantified for strength exercises. We therefore assessed acute cardiorespiratory responses during brief bouts of weight lifting exercises. METHODS: We compared double- versus single-limb leg extensions and arm elevations, as well as arm elevation done above or below shoulder level in patients with moderate to severe COPD (n = 10, 6 males, 66 (8...
April 19, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28417586/icu-mortality-is-increased-with-high-admission-serum-osmolarity-in-all-patients-other-than-those-admitted-with-pulmonary-diseases-and-hypoxia
#9
Shailesh Bihari, Shivesh Prakash, Sandra L Peake, Michael Bailey, David Pilcher, Andrew Bersten
BACKGROUND AND OBJECTIVE: High serum osmolarity has been shown to be lung protective. There is lack of clinical studies evaluating the impact on outcomes such as mortality. We aimed to examine the effect of serum osmolarity on intensive care unit (ICU) mortality in critically ill patients METHODS: Data from January 2000 to December 2012 was accessed using the Australian and New Zealand Intensive Care Society (ANZICS) Clinical Outcomes and Resource Evaluation (CORE) database. A total of 509 180 patients were included...
April 17, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28417583/ethnic-differences-in-the-pathogenesis-of-obstructive-sleep-apnoea-exploring-non-anatomical-factors
#10
EDITORIAL
Abd A Tahrani
No abstract text is available yet for this article.
April 17, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28409851/response-to-a-combination-of-oxygen-and-a-hypnotic-as-treatment-for-obstructive-sleep-apnoea-is-predicted-by-a-patient-s-therapeutic-cpap-requirement
#11
Shane A Landry, Simon A Joosten, Scott A Sands, David P White, Atul Malhotra, Andrew Wellman, Garun S Hamilton, Bradley A Edwards
BACKGROUND AND OBJECTIVE: Upper airway collapsibility predicts the response to several non-continuous positive airway pressure (CPAP) interventions for obstructive sleep apnoea (OSA). Measures of upper airway collapsibility cannot be easily performed in a clinical context; however, a patient's therapeutic CPAP requirement may serve as a surrogate measure of collapsibility. The present work aimed to compare the predictive use of CPAP level with detailed physiological measures of collapsibility...
April 13, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28401621/mouse-models-of-severe-asthma-understanding-the-mechanisms-of-steroid-resistance-tissue-remodelling-and-disease-exacerbation
#12
REVIEW
Steven Maltby, Hock L Tay, Ming Yang, Paul S Foster
Severe asthma has significant disease burden and results in high healthcare costs. While existing therapies are effective for the majority of asthma patients, treatments for individuals with severe asthma are often ineffective. Mouse models are useful to identify mechanisms underlying disease pathogenesis and for the preclinical assessment of new therapies. In fact, existing mouse models have contributed significantly to our understanding of allergic/eosinophilic phenotypes of asthma and facilitated the development of novel targeted therapies (e...
April 11, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28397998/determinants-of-peripheral-airway-function-in-adults-with-and-without-asthma
#13
Paul D Robinson, Gregory G King, Malcolm R Sears, Chuen Y Hong, Robert J Hancox
BACKGROUND AND OBJECTIVE: Peripheral airway involvement in asthma remains poorly understood. We investigated impulse oscillometry (IOS) measures of peripheral airway function in a population-based birth cohort. METHODS: Pre- and post-bronchodilator spirometry and IOS measures of respiratory resistance and reactance were measured in 915 participants at age 38 years. RESULTS: Current asthma was associated with impairments in both spirometry and IOS parameters...
April 11, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28397994/prevalence-of-obesity-hypoventilation-syndrome-in-ambulatory-obese-patients-attending-pathology-laboratories
#14
Jean-Christian Borel, Fabrice Guerber, Ingrid Jullian-Desayes, Marie Joyeux-Faure, Nathalie Arnol, Nellie Taleux, Renaud Tamisier, Jean-Louis Pépin
BACKGROUND AND OBJECTIVE: The prevalence of obesity hypoventilation syndrome (OHS) in the unselected obese is unknown. Our objectives were: (i) to determine the prevalence of OHS in ambulatory obese patients not previously referred to a pulmonologist for suspicion of sleep breathing disorders and (ii) to assess whether venous bicarbonate concentration [HCO3(-)v ] can be used to detect OHS. METHODS: In this prospective multicentric study, we measured [HCO3(-)v ] in consenting obese patients attending pathology analysis laboratories...
April 11, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28397992/mucoactive-agents-for-chronic-non-cystic-fibrosis-lung-disease-a-systematic-review-and-meta-analysis
#15
REVIEW
Benjamin J Tarrant, Caitlin Le Maitre, Lorena Romero, Ranjana Steward, Brenda M Button, Bruce R Thompson, Anne E Holland
Inhaled mucoactive agents are used in respiratory disease to improve mucus properties and enhance secretion clearance. The effect of mannitol, recombinant human deoxyribonuclease/dornase alfa (rhDNase) and hypertonic saline (HS) or normal saline (NS) are not well described in chronic lung conditions other than cystic fibrosis (CF). The aim of this review was to determine the benefit and safety of inhaled mucoactive agents outside of CF. We searched Medline, Embase, CINAHL and CENTRAL for randomized controlled trials investigating the effects of mucoactive agents on lung function, adverse events (AEs), health-related quality of life (HRQOL), hospitalization, length of stay, exacerbations, sputum clearance and inflammation...
April 11, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28382791/lymphatic-invasion-is-a-more-significant-prognostic-factor-than-visceral-pleural-invasion-in-non-small-cell-lung-cancer-with-tumours-of-3%C3%A2-cm-or-less
#16
Youngkyu Moon, Jae Kil Park, Kyo Young Lee, Sook Whan Sung
BACKGROUND AND OBJECTIVE: Visceral pleural invasion is an upstaging factor that increases cancer staging from stage IA to IB for tumours of 3 cm or less. However, lymphatic invasion has not been associated with the tumour-node-metastasis (TNM) staging system. The purpose of this study was to compare visceral pleural invasion and lymphatic invasion as prognostic factors. METHODS: We retrospectively reviewed 353 consecutive patients who underwent curative resection for stage I non-small cell lung cancer (NSCLC) tumours of 3 cm or less...
April 5, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28382762/nasopharyngeal-viral-pcr-in-immunosuppressed-patients-and-its-association-with-virus-detection-in-bronchoalveolar-lavage-by-pcr
#17
Daniel J Lachant, Daniel P Croft, Heather McGrane Minton, Paritosh Prasad, Robert M Kottmann
BACKGROUND AND OBJECTIVE: Pulmonary infiltrates are common in immunosuppressed patients. Bronchoscopy with bronchoalveolar lavage (BAL) is often used to evaluate their aetiology. However, it may not always be easily performed. Thus, alternative diagnostic strategies may be needed. There is limited data on the correlation of nasopharyngeal (NP) respiratory viral panel (RVP)-PCR testing compared with BAL. We aimed to identify the predictive value of NP RVP-PCR samples compared with samples obtained from BAL in immunosuppressed patients with pulmonary infiltrates...
April 5, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28374969/randomized-cross-over-trial-of-ventilator-modes-during-non-invasive-ventilation-titration-in-amyotrophic-lateral-sclerosis
#18
Bart Vrijsen, Bertien Buyse, Catharina Belge, Goele Vanpee, Philip Van Damme, Dries Testelmans
BACKGROUND AND OBJECTIVE: Non-invasive ventilation (NIV) improves survival, quality of life and sleep in patients with amyotrophic lateral sclerosis (ALS). Nevertheless, NIV titration is conducted in different ways. We aim to provide more insight into NIV titration by comparing the effects of a spontaneous (S) and spontaneous-timed (ST) modes on gas exchange, sleep architecture and patient-ventilator asynchronies (PVAs). METHODS: After an initial night of NIV titration, patients were randomized to S or ST mode in a cross-over design...
April 4, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28374936/effect-of-smoking-on-resting-state-functional-connectivity-in-smokers-an-fmri-study
#19
Shuang Zhou, Dan Xiao, Peng Peng, Shuang-Kun Wang, Zhao Liu, Hai-Yan Qin, Sheng-Shu Li, Chen Wang
BACKGROUND AND OBJECTIVE: Smoking is a leading cause of death in the world. Aberrant brain function has been repeatedly linked to tobacco smoking. However, little is known about insula-based resting-state functional connectivity (rsFC) in non-deprived tobacco-dependent smokers. This study characterized the correlation between insula-based rsFC and tobacco dependence severity in non-deprived smokers. METHODS: A total of 37 male smokers and 37 age-matched male non-smokers completed resting-state functional MRI (fMRI) scans...
April 4, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28370834/nintedanib-for-idiopathic-pulmonary-fibrosis-in-the-japanese-population
#20
EDITORIAL
Helen E Jo, Tamera J Corte
No abstract text is available yet for this article.
April 3, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
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