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Respirology: Official Journal of the Asian Pacific Society of Respirology

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https://www.readbyqxmd.com/read/30011423/pulmonary-infarction-a-disease-of-the-mostly-young
#1
EDITORIAL
Victor F Tapson
No abstract text is available yet for this article.
July 16, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/30011421/multidimensional-improvement-in-connective-tissue-disease-associated-interstitial-lung-disease-two-courses-of-pulse-dose-methylprednisolone-followed-by-low-dose-prednisone-and-tacrolimus
#2
Yasuhiko Yamano, Hiroyuki Taniguchi, Yasuhiro Kondoh, Masahiko Ando, Kensuke Kataoka, Taiki Furukawa, Takeshi Johkoh, Junya Fukuoka, Koji Sakamoto, Yoshinori Hasegawa
BACKGROUND AND OBJECTIVE: Corticosteroids and immunosuppressive agents are considered mainstays of therapy for connective tissue disease-related interstitial lung disease (CTD-ILD); however, tacrolimus with corticosteroid therapy has not been fully investigated. Our objectives were to examine the multidimensional therapeutic benefit and tolerability of the combined therapy for the initial treatment of patients with CTD-ILD. METHODS: In this retrospective case series, we identified consecutive CTD-ILD patients treated with tacrolimus plus intravenous (i...
July 16, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/30003637/towards-an-assessment-of-perceived-copd-exacerbation-triggers-initial-development-and-validation-of-a-questionnaire
#3
Chelsey A Werchan, Ashton M Steele, Thomas Janssens, Mark W Millard, Thomas Ritz
BACKGROUND AND OBJECTIVE: Prevention of exacerbations in chronic obstructive pulmonary disease (COPD) is important to decrease overall declines in functioning and improve quality of life. The present study sought to develop a psychometrically valid measure of perceived triggers of exacerbations in COPD patients, the COPD Exacerbation Trigger Inventory (CETI). METHODS: Participants (n = 192) were recruited through local clinics and online to complete surveys of the CETI, demographic information, disease-specific information and the COPD Assessment Test (CAT)...
July 13, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29992713/continuous-positive-airway-pressure-for-obstructive-sleep-apnoea-does-not-improve-asthma-control
#4
Susanna S S Ng, Tat-On Chan, Kin-Wang To, Ken K P Chan, Jenny Ngai, Wing-Ho Yip, Rachel L P Lo, Fanny W S Ko, David S C Hui
BACKGROUND AND OBJECTIVE: Unrecognized obstructive sleep apnoea syndrome (OSAS) may lead to poor asthma control despite optimal therapy. We assessed asthma control, airway responsiveness, daytime sleepiness and health status at baseline and 3 months after continuous positive airway pressure (CPAP) treatment among asthma patients with nocturnal symptoms and OSAS. METHODS: Patients with nocturnal asthma symptoms despite receiving at least moderate-dose inhaled corticosteroid and long-acting bronchodilators underwent a home sleep study using 'Embletta' portable diagnostic system...
July 10, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29974559/is-the-consumption-of-fast-foods-associated-with-asthma-or-other-allergic-diseases
#5
REVIEW
Cheng S Wang, Ji Wang, Xin Zhang, Li Zhang, Hong P Zhang, Lei Wang, Lisa G Wood, Gang Wang
The associations between the consumption of fast foods and asthma or allergic diseases have not been clarified. The aim of this study was to determine whether fast foods consumption is associated with asthma or allergic diseases. Databases were searched up to February 2018. Studies investigating the associations between fast foods consumption and asthma or allergic diseases were considered eligible. Included studies were assessed for quality using standardized critical appraisal checklists. The quality scores were 5...
July 4, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29966171/risk-factors-for-pleural-effusion-recurrence-in-patients-with-malignancy
#6
Horiana B Grosu, Sofia Molina, Roberto Casal, Juhee Song, Liang Li, Javier Diaz-Mendoza, Chakravarthy Reddy, Lonny Yarmus, Dante Schiavo, Michael Simoff, Jared Johnstun, Abu-Awwad Raid, David Feller-Kopman, Hans Lee, Sarina Sahetya, Finbar Foley, Fabien Maldonado, Xin Tian, Laila Noor, Russell Miller, Lakshmi Mudambi, Timothy Saettele, Macarena Vial-Rodriguez, Gerogie A Eapen, David E Ost
BACKGROUND AND OBJECTIVE: The main purpose of treatment in patients with malignant pleural effusion (MPE) is symptom palliation. Currently, patients undergo repeat thoracenteses prior to receiving a definitive procedure as clinicians are not aware of the risk factors associated with fluid recurrence. The primary objective of this study was to identify risk factors associated with recurrent symptomatic MPE. METHODS: Retrospective multicentre cohort study of patients who underwent first thoracentesis was performed...
July 2, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29956871/expression-analysis-of-extracellular-microrna-in-bronchoalveolar-lavage-fluid-from-patients-with-pulmonary-sarcoidosis
#7
Amit Kishore, Zdenka Navratilova, Vitezslav Kolek, Eva Novosadova, Klára Čépe, Roland M du Bois, Martin Petrek
BACKGROUND AND OBJECTIVE: MicroRNA (miRNA) are transcriptional regulators implicated in pulmonary sarcoidosis and packaged in extracellular vesicles (EV) during cellular communication. We characterized EV and investigated miRNA expression in bronchoalveolar lavage (BAL) fluid from sarcoidosis patients. METHODS: EV were characterized for size(s) using dynamic light scattering and transmission electron microscopy (TEM) analysis and protein markers by immunoblotting...
June 29, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29945291/glucold-eosinophils-and-chronic-obstructive-pulmonary-disease
#8
EDITORIAL
Ian D Pavord
No abstract text is available yet for this article.
June 26, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29943875/inflammation-dependent-and-independent-airway-remodelling-in-asthma
#9
John G Elliot, Peter B Noble, Thais Mauad, Tony R Bai, Michael J Abramson, Karen O McKay, Francis H Y Green, Alan L James
BACKGROUND AND OBJECTIVE: The pathology of asthma is characterized by airway inflammation (granulocytic (GA) or paucigranulocytic (PGA)) and remodelling of airway structures. However, the relationship between inflammatory phenotypes and remodelling is unclear. We hypothesized that some features of airway remodelling are dependent on granulocytic airway inflammation while others are not. METHODS: Post-mortem airway sections from control subjects (n = 48) and cases of asthma with (n = 51) or without (n = 29) granulocytic inflammation in the inner airway wall were studied...
June 26, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29943514/targeting-dyspnoea-in-patients-with-very-severe-copd-practical-precision-medicine
#10
EDITORIAL
Bartolome R Celli
No abstract text is available yet for this article.
June 25, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29943489/metformin-is-associated-with-a-lower-risk-of-active-tuberculosis-in-patients-with-type-2-diabetes
#11
Shang-Yi Lin, Hung-Pin Tu, Po-Liang Lu, Tun-Chieh Chen, Wen-Hung Wang, Inn-Wen Chong, Yen-Hsu Chen
BACKGROUND AND OBJECTIVE: Metformin is an oral anti-diabetic therapy (ADT) to manage type 2 diabetes mellitus (T2DM), and has been reported to have potential anti-tuberculosis (TB) effects. This study investigates the risk of active TB among persons with T2DM who were treated with various ADT and insulin therapies. METHODS: We conducted a nationwide population-based cohort study using the Taiwan Longitudinal Health Insurance Database, including 49 028 T2DM patients who were metformin users (n = 44 002) or non-users (n = 5026)...
June 25, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29924458/current-controversies-in-the-stepping-up-and-stepping-down-of-inhaled-therapies-for-copd-at-the-patient-level
#12
REVIEW
Jose Luis Lopez-Campos, Laura Carrasco Hernández, Xavier Muñoz, Víctor Bustamante, Esther Barreiro
The implementation of potential new step-up or step-down treatment recommendations in response to current guidelines is one of the main challenges currently faced in actual daily practice settings. In the present narrative review, we aim to discuss the relevance of these step-up and step-down proposals at the patient level in daily clinical practice. In particular, we aim to review the challenges associated with inhaled maintenance therapy for chronic obstructive pulmonary disease (COPD) in four clinical scenarios...
June 20, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29923364/annual-southeast-asia-haze-increases-respiratory-admissions-a-2-year-large-single-institution-experience
#13
Chew R Ming, Andrea Ban Yu-Lin, Mohammad F Abdul Hamid, Mohd T Latiff, Nurashikin Mohammad, Tidi Hassan
BACKGROUND AND OBJECTIVE: The Southeast Asia (SEA) haze is an annual problem and at its worst could produce respirable particles of concentrations up to 500 μg/m3 which is five times the level considered as 'unhealthy'. However, there are limited reports examining the direct clinical impact of the annual haze. This study examines the effects of the SEA haze on respiratory admissions. METHODS: Data from all respiratory admissions in Universiti Kebangsaan Malaysia Medical Centre (UKMMC) from 1st January 2014 to 31st December 2015 were collected retrospectively from chart and electronic database...
June 19, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29917287/new-drugs-and-regimens-for-tuberculosis
#14
REVIEW
Kwok-Chiu Chang, Eric Nuermberger, Giovanni Sotgiu, Chi-Chiu Leung
Since standardized rifampin-based first-line regimens and fluoroquinolone-based second-line regimens were used to treat tuberculosis (TB), unfortunately without timely modification according to the drug resistance profile, TB and drug-resistant disease are still important public health threats worldwide. Although the last decade has witnessed advances in rapid diagnostic tools and use of repurposed and novel drugs for better managing drug-resistant TB, we need an appropriate TB control strategy and a well-functioning health infrastructure to ensure optimal operational use of rapid tests, judicious use of effective treatment regimens that can be rapidly tailored according to the drug resistance profile and timely management of risk factors and co-morbidities that promote infection and its progression to disease...
June 19, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29904985/malignant-airway-obstruction-what-to-do
#15
EDITORIAL
Martin J Phillips
No abstract text is available yet for this article.
June 14, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29901251/latent-tuberculosis-infection-opportunities-and-challenges
#16
REVIEW
Cynthia B E Chee, Randall Reves, Ying Zhang, Robert Belknap
Diagnosing and treating latent tuberculosis (TB) infection (LTBI) is recognized by the World Health Organization as an important strategy to accelerate the decline in global TB and achieve TB elimination. Even among low-TB burden countries that have achieved high rates of detection and successful treatment for active TB, a number of barriers have prevented implementing or expanding LTBI treatment programmes. Of those infected with TB, relatively few will develop active disease and the current diagnostic tests have a low predictive value...
June 14, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29897160/clinical-behaviour-of-patients-exposed-to-organic-dust-and-diagnosed-with-idiopathic-pulmonary-fibrosis
#17
Laurens J De Sadeleer, Stijn E Verleden, Els De Dycker, Jonas Yserbyt, Johny A Verschakelen, Eric K Verbeken, Benoit Nemery, Geert M Verleden, Frederik Hermans, Bart M Vanaudenaerde, Wim A Wuyts
BACKGROUND AND OBJECTIVE: Although idiopathic pulmonary fibrosis (IPF) patients experience a worse survival compared with chronic hypersensitivity pneumonitis (CHP), organic dust exposure is a known risk factor for both IPF and CHP. METHODS: We divided patients diagnosed with IPF, based on their exposure to moulds/birds (absent: group A; present: group B). We retrospectively compared pulmonary function and survival between groups A and B, and a separate CHP cohort (group C)...
June 13, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29897157/could-quality-be-the-key-in-connective-tissue-disease-associated-interstitial-lung-disease
#18
EDITORIAL
Philip L Molyneaux, Toby M Maher
No abstract text is available yet for this article.
June 13, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29890567/red-cell-transfusion-and-clinical-outcomes-in-acute-pulmonary-embolism-harmful-therapy-or-an-indicator-of-sicker-patients-with-poor-prognosis
#19
EDITORIAL
Sanjeev D Chunilal, Erica M Wood
No abstract text is available yet for this article.
June 11, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29890566/red-blood-cell-transfusion-and-outcomes-in-acute-pulmonary-embolism-a-response
#20
LETTER
Christopher Wong, Austin Chin Chwan Ng, Leonard Kritharides
No abstract text is available yet for this article.
June 11, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
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