journal
MENU ▼
Read by QxMD icon Read
search

Allergology International: Official Journal of the Japanese Society of Allergology

journal
https://www.readbyqxmd.com/read/30391169/efficacy-and-safety-of-rupatadine-in-japanese-patients-with-seasonal-allergic-rhinitis-a-double-blind-randomized-multicenter-placebo-controlled-clinical-trial
#1
Kimihiro Okubo, Takamasa Suzuki, Ayaka Tanaka, Hiroshi Aoki
BACKGROUND: Rupatadine is a novel non-sedating second-generation H1 -antihistamine with antiplatelet-activating factor activity, first marketed in Spain in 2003. It is used for treating allergic rhinitis in more than 80 countries. This study investigated its efficacy and safety in Japanese patients with seasonal allergic rhinitis (SAR). METHODS: This was a randomized, placebo-controlled, double-blind study conducted at 4 medical institutions in Japan (JapicCTI-152785)...
October 31, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/30366757/a-comprehensive-understanding-of-the-gut-mucosal-immune-system-in-allergic-inflammation
#2
REVIEW
Daisuke Tokuhara, Yosuke Kurashima, Mariko Kamioka, Toshinori Nakayama, Peter Ernst, Hiroshi Kiyono
Despite its direct exposure to huge amounts of microorganisms and foreign and dietary antigens, the gut mucosa maintains intestinal homeostasis by utilizing the mucosal immune system. The gut mucosal immune system protects the host from the invasion of infectious pathogens and eliminates harmful non-self antigens, but it allows the cohabitation of commensal bacteria in the gut and the entry of dietary non-self antigens into the body via the mucosal surface. These physiological and immunological activities are regulated by the ingenious gut mucosal immune network, comprising such features as gut-associated lymphoid tissue, mucosal immune cells, cytokines, chemokines, antimicrobial peptides, secretory IgA, and commensal bacteria...
October 23, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/30355455/identification-of-biomarkers-for-predicting-the-response-to-cyclosporine-a-therapy-in-patients-with-chronic-spontaneous-urticaria
#3
LETTER
Takahiro Endo, Shota Toyoshima, Kazuko Kanegae, Satoshi Izaki, Nobuyuki Nishimori, Mana Ito, Kazuko Sugai, Koremasa Hayama, Tadashi Terui, Yoshimichi Okayama
No abstract text is available yet for this article.
October 22, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/30348485/reduced-nasal-nitric-oxide-levels-in-patients-with-eosinophilic-chronic-rhinosinusitis
#4
Kanako Yoshida, Tetsuji Takabayashi, Yoshimasa Imoto, Masafumi Sakashita, Norihiko Narita, Shigeharu Fujieda
BACKGROUND: In Eosinophilic chronic rhinosinusitis (ECRS), it is difficult to estimate the refractoriness and recurrence risk for each patient. Fraction of exhaled nitric oxide (FeNO) is known as a biomarker of eosinophilic inflammation in lower airway. It has been reported that nasal NO has some crucial functions in the upper and lower airways. However, in upper airway, paranasal sinuses, the usefulness of NO measurement remains controversial. The purpose of this study is to identify the usefulness of nasal NO measurement in ECRS and the involvement of nasal NO in the pathogenesis of ECRS...
October 19, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/30342889/sema4a-promotes-eosinophil-survival-and-contributes-to-eosinophil-mediated-allergic-diseases
#5
LETTER
Yohei Maeda, Takeshi Tsuda, Yoshito Takeda, Shohei Koyama, Yoshitomo Hayama, Satoshi Nojima, Tetsuya Kimura, Daisuke Ito, Hyota Takamatsu, Sujin Kang, Masayuki Nishide, Keiko Morimoto, Takashi Hosokawa, Yuhei Kinehara, Yasuhiro Kato, Takeshi Nakatani, Kazuya Takeda, Masaki Hayama, Sho Obata, Hitoshi Akazawa, Takashi Shikina, Hidenori Inohara, Atsushi Kumanogoh
No abstract text is available yet for this article.
October 17, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/30342888/efficacy-of-a-short-pretreatment-with-omalizumab-in-children-with-anaphylaxis-to-hymenoptera-venom-immunotherapy-a-report-of-three-cases
#6
LETTER
Catherine Droitcourt, Claude Ponvert, Alain Dupuy, Pierre Scheinmann, Rola Abou-Taam, Jacques de Blic, Guillaume Lezmi
No abstract text is available yet for this article.
October 17, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/30316748/significance-of-igg4-positive-cells-in-severe-eosinophilic-chronic-rhinosinusitis
#7
Takahisa Koyama, Shin Kariya, Yasuharu Sato, Yuka Gion, Takaya Higaki, Takenori Haruna, Tazuko Fujiwara, Akira Minoura, Soshi Takao, Yorihisa Orita, Kengo Kanai, Masami Taniguchi, Kazunori Nishizaki, Mitsuhiro Okano
BACKGROUND: IgG4 production is regulated by type 2 (IL-4 and IL-13) and regulatory (IL-10) cytokines involved in the pathophysiology of chronic rhinosinusitis (CRS). We sought to determine the pathophysiological characteristics of IgG4-positive cells in sinonasal tissues in CRS, especially eosinophilic CRS (ECRS). METHODS: IgG4-positive cells in uncinate tissues (UT) and nasal polyps (NP) were examined by immunohistochemistry. Associations between the number of IgG4-positive cells and clinicopathological factors were analyzed...
October 10, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/30309809/accuracy-of-objective-tests-for-diagnosing-adult-asthma-in-symptomatic-patients-a-systematic-literature-review-and-hierarchical-bayesian-latent-class-meta-analysis
#8
Hiroyuki Sano, Katsuyuki Tomita, Akiko Sano, Shou Saeki, Yusaku Nishikawa, Osamu Nishiyama, Takashi Iwanaga, Yuji Tohda
BACKGROUND: We obtain summary estimates of the accuracy of additional objective tests for the diagnosis of adult asthma using systematic review and meta-analysis of diagnostic test accuracy studies. METHODS: Medline, Embase, and other relevant electronic databases were searched for papers published between January 1989 and December 2016. Studies were included if they evaluated the diagnostic accuracy of objective tests, including airway reversibility (AR), airway hyperresponsiveness (AHR), and fractionated exhaled nitric oxide (FeNO) for the diagnosis of adult asthma in patients with symptoms suggestive of asthma...
October 8, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/30297096/usefulness-of-serum-biopterin-as-a-predictive-biomarker-for-childhood-asthma-control-a-prospective-cohort-study
#9
Saki Kasuga, Daijiro Kabata, Tomoko Sakaguchi, Satoshi Kudoh, Satsuki Nishigaki, Yusuke Higa, Shiori Fujikawa, Hiroko Fujitani, Ayumi Shintani, Takashi Hamazaki, Haruo Shintaku
BACKGROUND: Pteridines are metabolites of tetrahydrobiopterin, which serves as co-enzyme of nitric oxide synthase. We sought to investigate the usefulness of pteridines as biomarkers for childhood asthma control. METHODS: We conducted a single-center prospective cohort study involving 168 asthmatic children aged 4-17 years who visited the periodical asthma checkup program. Serum neopterin and biopterin levels were measured as pteridines at each visit along with measurement of FeNO, respiratory function tests, nasal eosinophil test, blood eosinophil count, and IgE level...
October 5, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/30279045/sensitization-to-api-m-1-api-m-2-and-api-m-4-in-japanese-beekeepers-who-had-experienced-systemic-reactions-to-honeybee-stings
#10
LETTER
Hirokuni Hirata, Kozo Sato, Takeshi Ogasawara, Tatsuo Funakoshi, Daisuke Shima, Masamitsu Tatewaki, Sadaaki Shiromori, Ryosuke Souma, Hideyuki Satoh, Kumiya Sugiyama, Masafumi Arima, Kazuhiro Kurasawa, Takeshi Fukuda, Yasutsugu Fukushima
No abstract text is available yet for this article.
September 29, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/30253946/severity-scales-of-non-ige-mediated-gastrointestinal-food-allergies-in-neonates-and-infants
#11
Hisako Yagi, Takumi Takizawa, Koichiro Sato, Takaharu Inoue, Yutaka Nishida, Takashi Ishige, Maiko Tatsuki, Reiko Hatori, Yasuko Kobayashi, Yoshiyuki Yamada, Hirokazu Arakawa
BACKGROUND: Non-IgE-mediated gastrointestinal food allergies (non-IgE-GI-FAs) are one type of food allergy found in neonates and infants. Few reports have defined the severity of non-IgE-GI-FAs in these populations. METHODS: Grading scales of the severity of non-IgE-GI-FAs according to extra-GI symptoms, such as poor weight gain, as well as systemic symptoms, including fever and shock, were developed and retrospectively applied to patients with non-IgE-GI-FAs. The relationship between the severity of non-IgE-GI-FAs and both clinical and laboratory findings were examined...
September 22, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/30249378/ultrasonographic-study-of-intestinal-doppler-blood-flow-in-infantile-non-ige-mediated-gastrointestinal-food-allergy
#12
Keisuke Jimbo, Yoshikazu Ohtsuka, Tatsuo Kono, Nobuyasu Arai, Reiko Kyoudo, Kenji Hosoi, Yo Aoyagi, Takahiro Kudo, Nobuyoshi Asai, Toshiaki Shimizu
BACKGROUND: Although non-IgE-mediated gastrointestinal food allergy has increased rapidly in Japan, a small number of reports has evaluated B-mode and Doppler ultrasonographic findings in the acute phase of infantile gastrointestinal milk allergy. The aim of the present study was to compare the diagnostic utility of ultrasonographic findings and laboratory allergic data in non-IgE-mediated infantile gastrointestinal milk allergy. METHODS: Sixteen cases of active non-IgE-mediated infantile gastrointestinal milk allergy, diagnosed by food elimination tests and oral food challenge tests (OFCTs) (group A), 15 cases of acute viral gastroenteritis (AGE) (group B), and 15 controls (group C) were enrolled...
September 22, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/30249379/stem-cell-factor-suppressed-il-33-induced-mhc-class-ii-expression-in-murine-bone-marrow-derived-mast-cells
#13
LETTER
Tomonobu Ito, Chizu Egusa, Tatsuo Maeda, Takafumi Numata, Nobuhiro Nakano, Chiharu Nishiyama, Ryoji Tsuboi
No abstract text is available yet for this article.
September 21, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/30217405/factors-determining-parenting-stress-in-mothers-of-children-with-atopic-dermatitis
#14
Chikae Yamaguchi, Takeshi Ebara, Rikuya Hosokawa, Masaki Futamura, Yukihiro Ohya, Midori Asano
BACKGROUND: Atopic dermatitis (AD) influences a child's emotional and social well-being, as well as his or her physical health. The influence of AD on the daily lives of parents and caregivers has also been documented. This study examined how parenting stress is affected by demographic background, characteristics of children's AD, and their family systems. METHODS: The participants were mothers of children, aged 2-6 years old, who had been diagnosed with AD. The predictive power of a model of parenting stress was examined using multiple regression analysis (stepwise), with parenting stress (PSI-SF) as the dependent variable, and children's demographics, including characteristics of AD; parents' demographics; QoL of families of children with AD (JCMV-CADIS); and family functioning (FAI) as independent variables...
September 11, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/30213444/characteristics-of-breath-sound-in-infants-with-risk-factors-for-asthma-development
#15
Hiromi Shioya, Hiromi Tadaki, Fusae Yamazaki, Manabu Miyamoto, Shigemi Yoshihara, Mayumi Enseki, Hideyuki Tabata, Kota Hirai, Hiroyuki Furuya, Masahiko Kato, Shuichi Ito, Hiroyuki Mochizuki
BACKGROUND: Breath sound parameters have been suggested as biomarkers of the airway narrowing in children. Using a commercially available breath sound analyzer, the characteristics of the airway condition were investigated in infants with the risk factors for asthma development. METHODS: A total of 443 infants (mean age, 9.9 months; range, 3-24 months) were included in the present study. The breath sound parameters of the frequency limiting 99% of the power spectrum (F99 ), the roll-off from 600 to 1200 Hz (Slope) and spectrum curve indices, the total area under the curve of the dBm data (A3 /AT ) and the ratio of power and frequency at 50% and 75% of the highest frequency of the power spectrum (RPF75 and RPF50 ), were evaluated...
September 10, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/30197185/cish-is-a-negative-regulator-of-il-13-induced-ccl26-production-in-lung-fibroblasts
#16
Hideyuki Takeshima, Masafumi Horie, Yu Mikami, Kosuke Makita, Naoya Miyashita, Hirotaka Matsuzaki, Satoshi Noguchi, Hirokazu Urushiyama, Yoshihisa Hiraishi, Akihisa Mitani, Zea Borok, Takahide Nagase, Yasuhiro Yamauchi
BACKGROUND: Bronchial asthma is a chronic airway disease characterized by eosinophilic airway inflammation. Lung fibroblasts activated by IL-13 serve as important sources of chemokines, such as eotaxins, contributing to persistent eosinophilic inflammation. Src-homology 2-containing protein (CISH), belonging to the suppressor of cytokine signaling (SOCS) family, acts as a negative regulator of cytokine induction. The aim of this study was to elucidate the role of CISH in the production of eosinophil chemotactic chemokines in human lung fibroblasts...
September 6, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/30190098/anaphylaxis-to-xylitol-diagnosed-by-skin-prick-test-and-basophil-activation-test
#17
LETTER
Kaoru Okamoto, Michiko Kagami, Manabu Kawai, Yuji Mori, Kazuo Yamawaki, Yoichi Nakajima, Yasuto Kondo, Ikuya Tsuge
No abstract text is available yet for this article.
September 3, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/30181013/a-case-of-human-seminal-plasma-allergy-sensitized-with-dog-prostatic-kallikrein-can-f-5
#18
LETTER
Mari Tanaka, Yukinobu Nakagawa, Yorihisa Kotobuki, Ichiro Katayama
No abstract text is available yet for this article.
September 1, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/30166059/role-of-whole-saliva-in-the-efficacy-of-sublingual-immunotherapy-in-seasonal-allergic-rhinitis
#19
Takenori Haruna, Shin Kariya, Tazuko Fujiwara, Atsushi Yuta, Takaya Higaki, Pengfei Zhao, Yukiko Ogawa, Kengo Kanai, Yuji Hirata, Aiko Oka, Kazunori Nishizaki, Mitsuhiro Okano
BACKGROUND: The development of methods to predict the clinical effectiveness of sublingual immunotherapy (SLIT) for allergic diseases is a crucial matter. We sought to determine whether whole saliva, which is the first body component that contacts allergen extracts during SLIT, is associated with the clinical effectiveness of SLIT in Japanese cedar pollinosis. METHODS: Blood monocytes or monocytic THP-1 cells were cultured in the presence or absence of either whole saliva or pure saliva with or without treatments including filtration and blockade of TLR2 and/or TLR4 signaling...
August 27, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/30146465/central-suppressant-therapies-in-unexplained-chronic-cough-patients-whose-sputum-cultures-yielded-bjerkandera-adusta
#20
LETTER
Haruhiko Ogawa, Kazuya Tone, Masaki Fujimura, Koichi Makimura
No abstract text is available yet for this article.
August 23, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
journal
journal
32642
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"