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Allergology International: Official Journal of the Japanese Society of Allergology

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https://www.readbyqxmd.com/read/29945815/natural-course-of-new-onset-urticaria-results-of-a-10-year-follow-up-nationwide-population-based-study
#1
Sang Jun Eun, Jin Yong Lee, Do-Yeop Kim, Hyun-Sun Yoon
BACKGROUND: Previous epidemiologic studies of the natural course of urticaria mainly focused on chronic spontaneous urticaria and were conducted at hospitals. The natural course of new-onset urticaria in the general population is unknown. METHODS: Patients with new-onset urticaria were identified from the National Health Insurance Service-National Sample Cohort data. Patients who had at least one visit for urticaria in 2002 and 2003 were excluded and the study cohort consisted of 1,027,620 subjects with no history of urticaria...
June 23, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29941231/soluble-st2-suppresses-il-5-production-by-human-basophilic-ku812-cells-induced-by-epithelial-cell-derived-il-33
#2
Koji Matsumoto, Hideaki Kouzaki, Hirotaka Kikuoka, Tomohisa Kato, Ichiro Tojima, Shino Shimizu, Takeshi Shimizu
BACKGROUND: Epithelial cell-derived IL-33 has an important role in the initiation and activation of innate allergic inflammation. IL-33 acts as a cytokine through the ST2 receptor (ST2L) and it stimulates the production of Th2 cytokines. Soluble ST2 (sST2) may regulate Th2 responses by neutralizing the activity of IL-33. Basophils express ST2L and produce IL-5 in response to IL-33. However, the role of the epithelial cell-basophil interaction and sST2 in IL-5 production remains unclear...
June 22, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29921489/examination-of-the-cut-off-values-for-a-questionnaire-used-to-evaluate-asthma-control-in-japanese-asthma-patients
#3
Yuji Tohda, Soichiro Hozawa, Hiroshi Tanaka
BACKGROUND: The Japan Asthma Control Survey (JACS) questionnaire, developed as a tool for measuring asthma control levels in Japanese asthma patients, was previously tested for its reliability and validity. However, many of the patients enrolled in the original validation study had mild asthma; thus a re-evaluation including severe cases was required to calculate more reliable cut-off values. METHODS: Pooled analysis of data from the original validation study and the subsequent medication guidance study including adult patients with severe asthma was conducted to calculate the JACS questionnaire cut-off values and to assess their sensitivity and specificity for identifying "well-controlled", "not well-controlled", and "poorly controlled" asthma as described in the Asthma Prevention and Management Guideline 2015 (JGL2015)...
June 16, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29921488/pediatric-case-with-rice-bran-allergy-induced-by-epicutaneous-sensitization-in-a-family-rice-shop
#4
LETTER
Yui Togashi, Naoko Inomata, Aki Suzuki, Amiko Hakuta, Michiko Aihara
No abstract text is available yet for this article.
June 16, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29910099/effects-of-anti-allergic-drugs-on-t-cell-mediated-nasal-hyperresponsiveness-in-a-murine-model-of-allergic-rhinitis
#5
Tomoe Nishimura, Osamu Kaminuma, Mayumi Saeki, Noriko Kitamura, Minoru Gotoh, Akio Mori, Takachika Hiroi
BACKGROUND: We have recently demonstrated that T cell-mediated nasal hyperresponsiveness (NHR) is a representative pathophysiological feature of allergic rhinitis (AR). Although several anti-allergic drugs are used for the treatment of AR, the efficacy of these drugs on T cell-mediated NHR have not been elucidated. In these studies we investigated the effects of dexamethasone (Dex), montelukast (Mk), and chlorpheniramine (Chl) on NHR in antigen-immunized and antigen-specific Th2 cell-transferred mice...
June 15, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29908674/analysis-of-factors-associated-with-cedar-pollen-sensitization-and-development-of-pollinosis-in-a-young-japanese-adult-population
#6
Satoshi Nakamura, Sachiko Tsunoda, Hiroshi Sakaida, Sawako Masuda, Ahamad Shah Said, Kazuhiko Takeuchi
BACKGROUND: Genetic and environmental factors are proposed to be involved in cedar pollen allergy sensitization and onset. The impact of these factors will provide key information for the prevention of cedar pollen sensitization and allergy onset, which we investigated in this cross-sectional study. METHODS: Subjects were 382 young adult volunteers who completed a self-administered questionnaire on self-reported subjective symptoms of pollinosis, physician-diagnosed pollinosis, and background factors...
June 13, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29903677/analyses-of-dermal-innate-lymphoid-cells-in-mice-lacking-t-bet-and-stat6
#7
LETTER
Sohei Makita, Hiroaki Takatori, Tomohiro Tamachi, Akira Suto, Kotaro Suzuki, Hiroshi Nakajima
No abstract text is available yet for this article.
June 11, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29866587/contact-dermatitis-with-concomitant-contact-urticaria-syndrome-due-to-multiple-ingredients-of-oxidative-hair-dye
#8
LETTER
Jun-Ichi Iwata, Naoko Inomata, Megumi Sato, Mami Miyakawa, Toshiko Kawaguchi, Michiko Aihara
No abstract text is available yet for this article.
June 1, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29857933/a-breath-sound-analysis-in-children-with-cough-variant-asthma
#9
Mayumi Enseki, Mariko Nukaga, Hiromi Tadaki, Hideyuki Tabata, Kota Hirai, Masahiko Kato, Hiroyuki Mochizuki
BACKGROUND: Cough variant asthma (CVA) is characterized by a chronic cough and bronchial hyperresponsiveness without confirmation of wheezing. Using a breath sound analyzer, we evaluate the characteristics of breath sound in children with CVA. METHODS: Nine children with CVA (median age, 7.0 years) participated. The existence of breath sounds was confirmed by sound spectrogram. Breath sound parameters, the frequency limiting 50% and 99% of the power spectrum (F50 and F99 ), the roll-off from 600 to 1200 Hz (Slope) and spectrum curve indices, the ratio of the third and fourth area to the total area of the power spectrum (P3 /PT and P4 /PT ) and the ratio of power and frequency at 50% and 75% of the highest frequency of the power spectrum (RPF75 and RPF50 ) were calculated before and after β2 agonist inhalation...
May 29, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29857932/an-independent-relation-of-atopic-dermatitis-to-exercise-induced-wheezing-in-asthmatic-children
#10
Satoshi Honjo, Yoko Murakami, Hiroshi Odajima, Yuichi Adachi, Koichi Yoshida, Yukihiro Ohya, Akira Akasawa
BACKGROUND: Atopic dermatitis (AD) and exercise-induced asthma (EIA) are common in asthmatic children, and exercise is the most common trigger other than infection for acute onset asthma attack in children. We examined whether AD is related to exercise-induced wheezing (EIW), some proxy for EIA. METHODS: Japanese version of the International Study of Asthma and Allergies in Childhood questionnaires were used. For 12,405 asthmatic school children, AD was defined as itchy rash coming and going for at least 6 months at any time in the last 12 months with affecting places of flexural parts of body, and severity of AD was rated according to frequency of being kept awake at night with the itch as follows: never in the past 12 months, less than one night per week and one or more nights per week...
May 29, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29805085/current-status-of-sublingual-immunotherapy-for-allergic-rhinitis-in-japan
#11
REVIEW
Keisuke Masuyama, Tomokazu Matsuoka, Atsushi Kamijo
Japanese cedar pollen (JCP) and house dust mite (HDM) are two major allergens that cause allergic rhinitis (AR) in Japan and the prevalence of AR is increasing. Pharmacothearpy is a commonly used treatment, but the level of patient satisfaction is very low. Allergen immunotherapy (AIT) is the only therapeutic modality that provides not only symptom relief but also quality of life improvement that leads to a high rate of satisfaction. In particular, sublingual immunotherapy (SLIT) is a safe and effective treatment for AR...
May 25, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29789204/quantification-of-the-%C3%AF-5-and-%C3%AE-gliadin-content-in-wheat-flour-and-rat-plasma-with-an-enzyme-linked-immunosorbent-assay-using-antibodies-specific-to-their-ige-binding-epitopes
#12
LETTER
Tomoharu Yokooji, Hitomi Nouma, Ryohei Ogino, Takanori Taogoshi, Eishin Morita, Hiroaki Matsuo
No abstract text is available yet for this article.
May 19, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29784282/characterization-of-human-decidual-mast-cells-and-establishment-of-a-culture-system
#13
Takayuki Matsuno, Shota Toyoshima, Tomomi Sakamoto-Sasaki, Jun-Ichi Kashiwakura, Akira Matsuda, Yasuo Watanabe, Hiromitsu Azuma, Kei Kawana, Tatsuo Yamamoto, Yoshimichi Okayama
BACKGROUND: Although rodent decidual mast cells (MCs) reportedly play an important role in implantation and placenta formation, the characterization of human decidual MCs has been not well clarified. The aims of this study were to investigate the distribution and characteristics of MCs in human decidua and to establish a culture system for decidua-derived MCs. METHODS: Decidual tissues were obtained from patients who underwent a legal elective abortion (6th week to 9th week of pregnancy), and decidual MCs were enzymatically dispersed...
May 18, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29779833/a-recurrent-case-of-eosinophilic-pneumonia-with-high-il-25-levels
#14
LETTER
Masaki Ikeda, Shigeki Katoh, Mikio Oka
No abstract text is available yet for this article.
May 17, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29779832/eosinophilic-vasculitis-affecting-multiple-middle-sized-arteries-in-a-patient-with-kimura-s-disease-a-case-report-and-literature-review
#15
LETTER
Hiroki Furuya, Kei Ikeda, Junya Suzuki, Kazumasa Suzuki, Kaito Nakamura, Shunsuke Furuta, Tomohiro Tamachi, Kotaro Suzuki, Koichi Hirose, Hiroshi Nakajima
No abstract text is available yet for this article.
May 17, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29773476/effects-of-%C3%AE-2-adrenergic-agonists-on-periostin-induced-adhesion-superoxide-anion-generation-and-degranulation-of-human-eosinophils
#16
LETTER
Toru Noguchi, Kazuyuki Nakagome, Takehito Kobayashi, Yutaka Ueda, Tomoyuki Soma, Hidetomo Nakamoto, Makoto Nagata
No abstract text is available yet for this article.
May 15, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29773475/concordance-between-aspergillus-specific-precipitating-antibody-and-igg-in-allergic-bronchopulmonary-aspergillosis
#17
Kazuki Harada, Tsuyoshi Oguma, Akemi Saito, Yuma Fukutomi, Jun Tanaka, Katsuyoshi Tomomatsu, Masami Taniguchi, Koichiro Asano
BACKGROUND: Several serological tests for specific precipitin or IgG are available to demonstrate type III hypersensitivity reactions to Aspergillus species and are essential for infectious fungal disease diagnosis. These assays are also important for allergic bronchopulmonary aspergillosis (ABPA) diagnosis; however, their concordance in ABPA was not well studied. METHODS: Fifty-two ABPA patients diagnosed based on ISHAM criteria were enrolled. Precipitins and IgG specific to Aspergillusfumigatus, Aspergillusniger, Aspergillusflavus, or Aspergillusterreus were measured using Ouchterlony double immunodiffusion tests and ImmunoCAP method, respectively...
May 15, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29759659/the-global-development-and-clinical-efficacy-of-sublingual-tablet-immunotherapy-for-allergic-diseases
#18
REVIEW
Hendrik Nolte, Jennifer Maloney
Allergy immunotherapy (AIT) is a treatment option for respiratory allergy that is complementary to pharmacotherapy, with a distinct mechanism of action. Alternative methods to subcutaneous administration of AIT that enable patients to safely self-administer AIT is considered an unmet clinical need. The sublingual immunotherapy tablet (SLIT-tablet) is an orally disintegrating pharmaceutical formulation (oral lyophilisate) containing standardized allergens. SLIT-tablets have been developed for sublingual immunotherapy (SLIT) of cedar-pollen, grass-pollen, ragweed-pollen, tree-pollen, and house dust mite allergies...
May 12, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29759658/three-cases-of-food-protein-induced-enterocolitis-syndrome-caused-by-egg-yolk
#19
LETTER
Masaki Shimomura, Hiroki Tanaka, Takaaki Meguro, Mitsuaki Kimura
No abstract text is available yet for this article.
May 11, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29754974/implication-of-fraction-of-exhaled-nitric-oxide-and-blood-eosinophil-count-in-severe-asthma
#20
Tomoyuki Soma, Hidetoshi Iemura, Erika Naito, Sachiko Miyauchi, Yoshitaka Uchida, Kazuyuki Nakagome, Makoto Nagata
BACKGROUND: Severe asthma is a complex disease with heterogeneous features and involves type 2 airway inflammation, including eosinophil accumulation. Surrogate biomarkers, fraction of exhaled nitric oxide (FeNO) and blood eosinophil count (b-EOS), may predict eosinophilic airway inflammation. Here we investigated clinical characteristics of severe asthma phenotype using a combined analysis of FeNO and b-EOS. METHODS: This retrospective study examined clinical data of patients with severe asthma (N = 107; median age, 64 years) treated at Saitama Medical University Hospital from 2009 to 2016...
May 10, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
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