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Journal of Cutaneous Medicine and Surgery

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https://www.readbyqxmd.com/read/29466863/observe-5-comparison-of-etanercept-treated-psoriasis-patients-from-canada-and-the-united-states
#1
Kim A Papp, Marc Bourcier, Yves Poulin, Charles W Lynde, Martin Gilbert, Melanie Poulin-Costello, Lieven Billen, Maya Isaila
BACKGROUND: OBSERVE-5 surveillance registry results evaluating etanercept safety and effectiveness in patients with moderate to severe psoriasis from Canada and the United States have been reported from data collected between May 2006 and December 2012. Although both countries have an identical indicated starting dose, the maintenance dose can differ and thus affect management strategies and outcomes. OBJECTIVE: To compare the long-term safety and effectiveness outcomes of etanercept in the Canadian and US cohorts...
February 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29463114/a-case-report-highlighting-the-effective-treatment-of-alopecia-universalis-with-tofacitinib-in-an-adolescent-and-adult-patient
#2
Nupur U Patel, Elias Oussedik, Alexandra Grammenos, Rita Pichardo-Geisinger
No abstract text is available yet for this article.
February 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29463113/pediatric-lip-adhesion-following-bullous-erythema-multiforme-and-review-of-similar-oral-complications
#3
Rosalind Ashton, Karen W Wong, Miriam Weinstein
BACKGROUND: Erythema multiforme (EM) is a mucocutaneous disease most often associated with preceding herpes simplex virus or Mycoplasma pneumoniae infection. It is characterized by targetoid lesions occurring on the limbs and head and neck. Mucosal involvement can be extensive. OBJECTIVE: We report a case of lip adhesion as a complication of EM in a child who required corrective surgery and review similar oral commissure complications. METHODS: We completed a review of the literature for similar cases using PubMed and Medline...
February 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29457486/case-report-of-empagliflozin-induced-cutaneous-polyarteritis-nodosa
#4
Derek To, Scott Bradshaw, Jennifer Lipson
Polyarteritis nodosa (PAN) is a rare vasculitis affecting medium-sized vessels. Cutaneous PAN is a clinical variant, and we report the first case of empagliflozin-induced cutaneous PAN in a 69-year-old man. After starting empagliflozin, the patient presented with tender subcutaneous nodules on his legs, which showed a medium-sized vessel vasculitis on histopathology. Upon cessation of this medication, he had full resolution of these nodules. This case illustrates that empagliflozin can induce cutaneous PAN, and further attention to this medication's association with cutaneous PAN is warranted...
February 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29457485/atopy-associated-with-positive-patch-test-and-possible-allergic-contact-dermatitis
#5
Mark G Kirchhof, Gillian C de Gannes
BACKGROUND: Atopy is a genetic predisposition to the development of allergic reactions and the increased production of immunoglobulin E (IgE) upon exposure to environmental antigens. Clinical manifestations of atopy include asthma, atopic dermatitis (AD), and allergic rhinoconjunctivitis (ARC). OBJECTIVE: To determine if cutaneous delayed hypersensitivity reactions (CDHRs) as assessed by patch testing are higher among patients with a history of atopy and with a familial predisposition to atopy...
February 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29457484/cryosurgery-5-5-fluorouracil-for-treatment-of-superficial-basal-cell-carcinoma-and-bowen-s-disease
#6
Laura C Soong, Christopher P Keeling
BACKGROUND: Superficial basal cell carcinoma (sBCC) and squamous cell carcinoma in situ (SCCis) are 2 types of nonmelanoma skin cancers (NMSCs) that are amenable to treatment with topical 5-fluorouracil, cryosurgery, or topical imiquimod, among other destructive and surgical modalities. There are few studies examining the effectiveness of combination therapy with 5% 5-fluorouracil and cryosurgery for the treatment of sBCC and SCCis. OBJECTIVES: Our objective was to study the clinical cure rate achieved with the regimen of cryosurgery and a 3-week course of 5% 5-fluorouracil in the treatment of biopsy-proven sBCC and SCCis...
February 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29448815/topiramate-induced-acne-in-a-31-year-old-woman-a-case-report
#7
Alanna C Bridgman, Philip R Doiron
No abstract text is available yet for this article.
February 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29421925/pediatric-stevens-johnson-syndrome-toxic-epidermal-necrolysis-halted-by-etanercept
#8
Geneviève M Gavigan, Nordau D Kanigsberg, Michele L Ramien
We report a case of an 11-year-old female with Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) overlap, most likely triggered by sulfamethoxazole-trimethoprim, who was treated with the combination of methylprednisolone, cyclosporine, and etanercept. Her condition stabilized and her skin involvement did not progress after the addition of etanercept. To our knowledge, this is the first report of etanercept for pediatric SJS/TEN.
February 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29421924/a-13-year-old-presenting-with-recurrent-angioma-serpiginosum
#9
Michael Bishara, Michael Jiaravuthisan, Miriam Weinstein
BACKGROUND: Angioma serpiginosum (AS) is a rare vascular abnormality consisting of proliferation and dilation of superficial blood vessels in the skin. AS typically presents in the first 2 decades of life and remains stable with time. CASE SUMMARY: We report the case of a 13-year-old female with an acquired, recurrent erythematous lesion with serpiginous borders on her left upper arm. Over several years, the lesion reappeared then disappeared 12 to 15 times. At one point, she developed a tender red nodule within the lesion; consequently, a biopsy was taken, revealing dilated telangiectatic vessels in the dermal papillae with mild, focal extravasation of erythrocytes...
February 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29411629/clinical-texting-among-medical-trainees-of-the-university-of-british-columbia
#10
Danny Guo, Nam Phan, Kendall Ho, John Pawlovich, Neil Kitson
We believe cellphone text messages are commonly used in medical practice whether in rural or urban settings and that clinical photos are often attached to them. Our interest is the use of this technology to provide dermatology service to rural and remote British Columbia. Concern has been expressed about the security of confidential information and adequacy of privacy protection in such an application. We have found little published information about the extent of texting in rural and remote settings (and none in our jurisdiction) or the number and nature of privacy breaches that have actually occurred as a result...
February 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29400079/drug-eruption-to-rosuvastatin-with-recurrence-on-simvastatin-a-case-report
#11
Ian T Y Wong, Yuanshen Huang, Youwen Zhou
No abstract text is available yet for this article.
February 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29383948/nevoid-basal-cell-carcinomata-mimicking-melanocytic-nevi-case-report
#12
Emma Heck, Habib Kurwa, Lynne Robertson
No abstract text is available yet for this article.
January 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29383947/development-of-a-comprehensive-quality-of-life-measure-for-facial-and-torso-acne
#13
Chelsea McLellan, Marc P Frey, Diane Thibotout, Alison Layton, Mary-Margaret Chren, Jerry Tan
Background Acne is a chronic skin disorder which generally presents in adolescence but continues into adulthood, and negatively affects both physical and psychosocial well-being. Presently, there are no validated acne-specific quality-of-life (QoL) measures that include dimensions for both facial and torso acne. OBJECTIVE: The objective of this study was to develop a QoL instrument for both facial and torso acne (CompAQ) in accordance with recommended standards. METHODS: A literature review and Delphi survey of patients and clinicians were used to develop the conceptual framework for outcomes perceived important to acne patients...
January 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29373925/disseminated-eczema-following-radiotherapy-a-case-report
#14
Alia Bosworth, Peter R Hull
BACKGROUND: Radiotherapy-induced acute skin reactions are common and an expected effect of radiotherapy. Eczematous eruptions, however, are rarely reported, with disseminated eczema in particular being infrequently seen and likely underrecognized. OBJECTIVE: We present a unique case of disseminated vesicular eczema following radiotherapy for ductal carcinoma in situ. CONCLUSIONS: The development of a localized vesicular eruption with subsequent dissemination can occur following radiotherapy...
January 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29373924/efficacy-and-safety-of-apremilast-monotherapy-for-moderate-to-severe-psoriasis-retrospective-study
#15
Arvin Ighani, Jorge R Georgakopoulos, Linda L Zhou, Scott Walsh, Neil Shear, Jensen Yeung
BACKGROUND: Apremilast is a new oral drug for the treatment of moderate to severe plaque psoriasis that reduces inflammation by inhibiting phosphodiesterase 4. Its efficacy and safety data are limited; hence, real-world outcomes are important for elucidating the full spectrum of its adverse events (AEs) and expanding generalizability of clinical trial findings. OBJECTIVE: Assess the efficacy and safety of apremilast monotherapy in real-world practice. METHODS: A retrospective chart review was conducted in 2 academic dermatology practices...
January 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29373923/a-unique-case-of-cutaneous-larva-migrans-acquired-within-the-province-of-quebec-and-successfully-treated-with-topical-ivermectin
#16
Anne-Sophie Smilga, Janie Bujold
Cutaneous larva migrans (CLM) is a zoonotic helminthiasis frequently imported to Canada by travellers to beach destinations in the tropics. The preferred treatment is oral ivermectin. We present a case of CLM acquired within the province of Quebec, a first in our provincial health records. Our case also puts forward the use of topical ivermectin as a possibly effective CLM treatment approach as our patient was successfully treated with 1 month of an ivermectin 1% cream applied locally twice daily.
January 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29366337/extensive-cutaneous-botryomycosis-with-subsequent-development-of-nocardia-positive-wound-cultures
#17
Judy Park DeWitt, Cloyce L Stetson, Kleesy L Thomas, Bryan J Carroll
Botryomycosis is a rare, chronic granulomatous infection caused by a response to bacteria, most commonly Staphylococcus aureus. Cutaneous manifestations, such as subcutaneous nodules, nonhealing ulcers, or sinus tracks, typically occur following inoculation of bacteria after trauma. Drainage from the skin lesions may contain yellow grains resembling those seen in actinomycosis and nocardiosis. A 20-year-old Hispanic male presented over the course of several years with a chronic nonhealing left posterior scalp wound...
January 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29357685/case-based-learning-in-dermatology
#18
Annie Liu, Linghong Linda Zhou, Andrea Lam, Erin Dahlke
IMPORTANCE: The instruction of dermatology can be challenging due to its large scope, heavy clinical nature, and limited curriculum space. Case-based learning (CBL) is an emerging education paradigm and has no current literature on its use in dermatology. OBJECTIVES: Assess CBL in undergraduate dermatology medical education. METHODS: Case-based learning was implemented in the preclerkship dermatology curriculum at the University of Toronto to 3 student cohorts (totaling 710 students and 93 tutors) between May 2016 and April 2017...
January 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29351725/daylight-mediated-photodynamic-therapy-with-methyl-aminolevulinate-in-actinic-keratosis-treatment
#19
Shantel D J Demay, Kunal Sharma, Sheetal Sapra, Rahul Sapra, Priya Sapra
BACKGROUND: Research has shown daylight-mediated photodynamic therapy (PDT) for the treatment of actinic keratosis (AK) to be effective, tolerable, and convenient, with excellent patient satisfaction and cosmesis. Although success has been demonstrated in areas with similar latitudes to Switzerland and Scandinavia, this treatment has not been studied in a Canadian population. OBJECTIVES: The purpose of this study is to investigate the effectiveness, safety, and patient satisfaction of daylight-mediated methyl 5-aminolevulinate (MAL)-PDT to make recommendations for its use in Canadian practice...
January 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29332425/dermatological-manifestations-in-patients-undergoing-in-vitro-fertilisation-a-prospective-study
#20
Aradhana Sood, Suvash Sahu, Sandeep Karunakaran, Rajneesh K Joshi, Deep Kumar Raman
BACKGROUND: Changing sociodemographic patterns with an increase in the age of childbirth have affected fertility rates worldwide. With advancing reproductive medicine, assisted reproductive techniques (ARTs) are becoming common. While dermatological manifestations in normal pregnancies have been well documented, there is a paucity of data regarding cutaneous manifestations in patients undergoing ART. OBJECTIVES: The objectives of our study were to estimate the incidence and types of dermatological manifestations in patients undergoing in vitro fertilisation (IVF) and to study their associations with age, type of infertility, and outcome of the procedure...
January 1, 2018: Journal of Cutaneous Medicine and Surgery
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