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Journal of Cutaneous Medicine and Surgery

Fatima Aloraifi, Stephen Mulgrew, Nick K James
Merkel cell carcinoma (MCC) is a highly aggressive cutaneous neuroendocrine tumour that is increasing in incidence. We report a case of a 92-year-old white man on long-term immunosuppression for temporal arteritis who presented with a Merkel cell tumour on his left cheek. A wide local excision was performed and the defect was reconstructed with a full-thickness skin graft. Four years later, the patient re-presented with a Merkel cell tumour arising from the right supraclavicular donor site. To our knowledge, this is the first report of a recurrence of MCC into a donor site...
October 24, 2016: Journal of Cutaneous Medicine and Surgery
Marius Rademaker
No abstract text is available yet for this article.
October 24, 2016: Journal of Cutaneous Medicine and Surgery
María Librada Porriño-Bustamante, José Aneiros-Fernández, Juan Antonio Retámero, María Antonia Fernández-Pugnaire
Hobnail hemangioma, also known as targetoid hemosiderotic hemangioma, is an uncommon vascular proliferation that clinically presents as a small solitary red to purple papule or macule, located on the limbs or trunk. Multiple lesions and atypical locations have been described. Histopathologically, it exhibits a biphasic pattern, with dilated vessels in the superficial dermis and angulated vessels in the deeper dermis, with endothelial cells that show a hobnail appearance. There is controversy about the histogenetic origin of hobnail hemangioma, although recent studies support that it is a lymphatic malformation...
October 5, 2016: Journal of Cutaneous Medicine and Surgery
Karishma Desai, Marc Philip Frey, Jerry Tan
BACKGROUND: Acne grading is an essential component in establishing treatment options, but little is known on how neck acne should be incorporated into grading scales. OBJECTIVE: Our objective was to explore the prevalence of neck acne and determine if its own severity category on an acne global grading scale was warranted. METHODS: Acne severity was assessed in 6 categories: face, chest, back, anterior upper (AUN), anterior lower neck (ALN), and posterior neck (PN)...
October 3, 2016: Journal of Cutaneous Medicine and Surgery
Sarah Baldwin, Sheila Au
The Skin Cancer Post-Transplant (SCREEN) Clinic is a skin-cancer screening clinic that is fully integrated into the renal transplantation clinic at St Paul's Hospital in Vancouver, British Columbia. The purpose of this review was to determine characteristics of patients most at risk for skin cancer, to specify types and locations of skin cancers diagnosed, and to identify areas for patient and physician education. Transplant patients (91% renal; 5% heart) screened by a dermatologist during a 12-month period were stratified into low-, medium-, and high-risk groups based on detailed history and skin examination...
September 23, 2016: Journal of Cutaneous Medicine and Surgery
Noelani E González, Rajiv I Nijhawan, Maritza I Perez
No abstract text is available yet for this article.
September 20, 2016: Journal of Cutaneous Medicine and Surgery
Melinda Gooderham, Charles W Lynde, Kim Papp, Marc Bourcier, Lyn Guenther, Wayne Gulliver, Chih-Ho Hong, Yves Poulin, Gordon Sussman, Ronald Vender
BACKGROUND: Atopic dermatitis (AD) is a chronic, pruritic inflammatory skin disease resulting from defects in skin barrier and aberrant immune responses. AD significantly affects the quality of life. Not all patients respond to topical therapies, and often systemic therapy is required to control the disease. OBJECTIVE: To review the treatment options for adult AD patients including those options for patients who do not respond adequately or have contraindications to oral systemic therapy...
September 15, 2016: Journal of Cutaneous Medicine and Surgery
Connie Zhang, Richard M Haber
Perineal streptococcal dermatitis (PSD) is largely known to be caused by group A β-hemolytic Streptococcus (GAS). We would like to bring cases of non-GAS PSD to the attention of dermatologists, as there are implications for workup and therapy. We report 3 pediatric cases of PSD: 1 caused by GAS, 1 caused by group B β-hemolytic Streptococcus (GBS), and 1 associated with group C β-hemolytic Streptococcus (GCS). GBS and GCS are very rarely reported in pediatric cases of PSD. The literature on non-GAS PSD is reviewed, which additionally revealed several instances of PSD caused by group G β-hemolytic Streptococcus (GGS) and Staphylococcus aureus GBS, GCS, GGS, and S aureus are significant causes of PSD to consider, particularly among adult patients, based on our encountered cases and the literature...
September 14, 2016: Journal of Cutaneous Medicine and Surgery
Jean-Philip Lacroix, Beatrice Wang
BACKGROUND: Dabrafenib, a novel selective small-molecule inhibitor of BRAF, has been shown to increase overall survival in patients with unresectable metastatic melanoma harboring the BRAF V600E mutation. The development of resistance has led to combination therapy with selective MEK inhibitor trametinib. Compared with vemurafenib, dabrafenib is a more recent BRAF inhibitor approved by the Food and Drug Administration in May 2013 for metastatic melanoma; fewer data are available in the current literature regarding cutaneous toxicity...
September 13, 2016: Journal of Cutaneous Medicine and Surgery
Sara Sherif, Elizabeth Blakeway, Chris Fenn, Alyn German, Philip Laws
Cutaneous reactions to tattoos are well reported and include allergic reactions, infections, and foreign body granuloma or may be a presenting sign of sarcoidosis. There have been very few reported cases of squamous cell carcinoma (SCC) arising in tattoo-treated skin. We report a case of SCC arising within a red-ink tattoo and discuss the potential the role of chronic low-grade inflammation in pathogenesis. This should serve to raise awareness of potential tattoo-related serious adverse effects.
September 13, 2016: Journal of Cutaneous Medicine and Surgery
Bahman Sotoodian, Mariam Abbas, Alain Brassard
BACKGROUND: Hidradenitis suppurativa (HS) is a chronic inflammatory disease affecting skin sites with a high density of apocrine glands. HS commonly presents after puberty, with most patients diagnosed in the second decade of their life. Several studies have investigated smoking, obesity, hypertension, diabetes, and dyslipidemia as possible underlying risk factors for HS. However, we encountered 2 patients with a long-standing history of untreated leukemia who developed late-onset HS...
August 29, 2016: Journal of Cutaneous Medicine and Surgery
Eoin R Storan, Susan M O'Gorman, Annette Murphy, Mary Laing
BACKGROUND: Calciphylaxis is a rare disorder that is very unusual outside the setting of end-stage kidney disease. CASE SUMMARY: A 64-year-old woman with normal renal function presented with painful leg ulcers. She had previously received 300 000 IU of vitamin D3 followed by daily calcium and vitamin D3 supplementation. A skin biopsy was consistent with calciphylaxis, and she was treated with sodium thiosulphate infusions and wound debridement. CONCLUSION: Calcium and vitamin D3 supplements are widely prescribed...
August 26, 2016: Journal of Cutaneous Medicine and Surgery
Judy K Qiang, Whan B Kim, Akerke Baibergenova, Raed Alhusayen
BACKGROUND: There is variation in the risk of malignancy in dermatomyositis (DM) and polymyositis (PM) in the existing literature. OBJECTIVE: To conduct a meta-analysis to estimate the risk of malignancy in DM and PM as compared with the general population. METHODS: Medline and Embase Database abstracts were searched through August 2014 using the search terms myositis, neoplasms, and paraneoplastic syndromes. Population-based, observational studies in English were included...
August 17, 2016: Journal of Cutaneous Medicine and Surgery
Allison K Cinats, Richard M Haber
Autoimmune hepatitis is a subtle diagnosis that has many diverse clinical presentations. It has been reported in the literature to occur concomitantly with pyoderma gangrenosum, a neutrophilic dermatosis. Sweet's syndrome is another neutrophilic dermatosis and has been reported to be associated with autoimmune hepatitis in only 2 previous cases: 1 idiopathic and 1 drug induced. Here we report a third case in a 24-year-old woman diagnosed with Sweet's syndrome in association with autoimmune hepatitis, documenting a possible trend between neutrophilic dermatoses and autoimmune hepatitis...
August 17, 2016: Journal of Cutaneous Medicine and Surgery
Mathew N Nicholas, Jensen Yeung
Chronic wounds, including diabetic ulcers, pressure ulcers, venous ulcers, and arterial insufficiency ulcers, are both difficult and expensive to treat. Conventional wound care may sometimes lead to suboptimal wound healing and significant morbidity and mortality for patients. The use of skin substitutes provides an alternative therapy showing superior efficacy and, in some cases, similar cost-effectiveness compared to traditional treatments. This review discusses the different types of currently available commercial skin substitutes for use in chronic wounds as well as the paucity of strong evidence supporting their use...
August 16, 2016: Journal of Cutaneous Medicine and Surgery
Lukas Kofler, Markus Wambacher, Katrin Schweinzer, Maritta Scherl, Heinz Kofler
Polyether ether ketone (PEEK) is a thermoplastic polymer frequently used in engineering but also in medical devices. Only 1 case of allergic reaction to PEEK used as an implanted medical device has been reported so far; however, the route of sensitization remained unclear. Here we report on a 62-year-old male patient with a preknown, severe type IV allergy to epoxy resin. He reported strong pain in his shoulder after implantation of a PEEK-containing device after a rotator cuff injury. For testing, the device was implanted in a small pouch subcutaneously on the abdomen...
August 12, 2016: Journal of Cutaneous Medicine and Surgery
Alexandra Kuzyk, Shane Silver, Sharon Wallace, Sate Hamza, John Toole
No abstract text is available yet for this article.
August 9, 2016: Journal of Cutaneous Medicine and Surgery
Danya Traboulsi, Habib Kurwa
BACKGROUND: Basal cell carcinoma (BCC) is the most common cutaneous malignancy. Terminal hair is not routinely removed for assessment of BCCs on the scalp and yet may obscure the true size of scalp BCCs. This can compromise effective management. OBJECTIVE: To underscore the importance of removing terminal hair on the scalp for an accurate assessment of clinical margins of BCC on the scalp. METHODS: We report 2 cases of cutaneous BCC arising on the scalp...
August 8, 2016: Journal of Cutaneous Medicine and Surgery
Kirk Barber
No abstract text is available yet for this article.
September 2016: Journal of Cutaneous Medicine and Surgery
(no author information available yet)
No abstract text is available yet for this article.
September 2016: Journal of Cutaneous Medicine and Surgery
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