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Journals Journal of Obstetrics and Gyna...

Journal of Obstetrics and Gynaecology Research

https://read.qxmd.com/read/38412992/cellular-senescence-in-the-pathogenesis-of-ovarian-dysfunction
#21
JOURNAL ARTICLE
Miyuki Harada
The follicular microenvironment is crucial for normal ovarian function, and intra-ovarian factors, in coordination with gonadotropins, contribute to its regulation. Recent research has revealed that the accumulation of senescent cells worsens the adverse environment of various tissues and plays critical roles in chronological aging and various pathological conditions. Cellular senescence involves cell-cycle arrest, a senescence-associated secretory phenotype (SASP), macromolecular damage, and dysmetabolism...
February 27, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38403851/letrozole-cotreatment-progestin-primed-ovarian-stimulation-in-women-undergoing-controlled-ovarian-stimulation-for-in-vitro-fertilization
#22
JOURNAL ARTICLE
Xiaoning Wang, Ying Zhang, Honglu Diao, Shengfang Jiang, Changjun Zhang
AIM: To investigate the impact of letrozole cotreatment progestin-primed ovarian stimulation (PPOS) (Le PPOS) in controlled ovarian stimulation (COS) and the pregnancy outcomes in frozen-thawed embryo transfer cycles. METHODS: This retrospective cohort study included women who underwent in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI). A total of 2575 cycles were included (1675 in the Le PPOS group and 900 in the PPOS group). The primary outcome was the clinical pregnancy rates...
February 25, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38369816/nationwide-status-of-progestogen-treatment-to-prevent-spontaneous-preterm-birth-a-questionnaire-survey-for-childbirth-healthcare-facilities-in-japan
#23
JOURNAL ARTICLE
Ikuno Kawabata, Takeshi Nagamatsu, Satoshi Yoneda, Rie Oi, Yoshio Matsuda, Akihito Nakai, Katsufumi Otsuki
AIM: This study aimed to investigate the current status of progestogen treatment for pregnant women at a high risk for preterm birth (PTB) in childbirth healthcare facilities in Japan. METHODS: A web-based nationwide questionnaire survey regarding progestogen use for prevention of PTB was conducted among childbirth healthcare facilities from 2019 to 2021. RESULTS: Valid responses were obtained from 528 facilities (25.2% of those surveyed), including 155 tertiary perinatal facilities (making up 92...
February 18, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38369640/prepregnancy-weight-loss-and-maternal-metabolic-and-inflammatory-biomarkers-during-pregnancy-an-analysis-of-national-health-and-nutrition-examination-survey
#24
JOURNAL ARTICLE
Yang Yu, Qianheng Ma, Susan Groth
AIM: Women with overweight or obesity are recommended to lose weight before conception to optimize pregnancy outcomes. However, the obstetrical implications of prepregnancy weight loss have been minimally examined. The objective of this study was to investigate the association between prepregnancy weight loss and maternal metabolic and inflammatory profiles during a subsequent pregnancy. METHODS: This study was a retrospective analysis of National Health and Nutrition Examination Survey data (2003-2018)...
February 18, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38366809/first-trimester-preterm-preeclampsia-prediction-model-for-prevention-with-low-dose-aspirin
#25
JOURNAL ARTICLE
Ritsuko Kimata Pooh
INTRODUCTION: Preeclampsia (PE) is a major maternal and fetal threat. Previous risk-scoring methods in guidelines lacked precision. The Fetal Medicine Foundation (FMF) proposed a first-trimester PE screening model using Bayes' theorem. PE PREDICTION MODEL: FMF prediction model combines maternal characteristics and medical/obstetrical history to determine prior risk and further incorporate maternal blood pressure, maternal serum biomarkers, and uterine Doppler pulsatility index expressed as multiples of the median (MoM) to estimate posterior risk...
February 17, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38366767/placental-abruption-incidence-and-risk-of-recurrence-in-subsequent-pregnancies
#26
JOURNAL ARTICLE
Yinka Oyelese, Morgan Peltier, Bridget Donovan, Nehaa Khadka, Vicki Y Chiu, Michael J Fassett, Darios Getahun
AIM: To estimate the incidence of abruption in first births and recurrence in the subsequent birth in patients of a large US-based integrated health care system. METHODS: Retrospective population-based cohort study of patients with first two consecutive singleton births using data from the Kaiser-Permanente South California health care system who delivered over a period of 30 years (1991-2021), using longitudinally linked electronic health records. ICD-9/ICD-10 codes "641...
February 17, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38350492/bioinformatics-analysis-identifies-potential-autophagy-key-genes-and-immune-infiltration-in-preeclampsia
#27
JOURNAL ARTICLE
Lu Sun, Yanhong He, Jie Chen, Xiaofeng Yang, Yuzhen Ding, Meiting Shi, Andong He, Ping Zhang, Zhengrui Huang, Ruiman Li
BACKGROUND: Preeclampsia (PE) is a disease that seriously threatens maternal and fetal health. Appropriate autophagy can shield the placenta from oxidative stress, but its role in PE is unclear. OBJECTIVE: To identify potential autophagy-related genes in PE. METHODS: Microarray datasets from the Gene Expression Omnibus database, compassing the test dataset GSE10588, along with validation datasets GSE4707 and GSE60438 GPL10558, were utilized...
February 13, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38339841/turkish-adaptation-of-the-reproductive-autonomy-scale-validity-and-reliability-study
#28
JOURNAL ARTICLE
Seda Hazar, Ceylan Güzel İnal, Gülçin Nacar, Sermin Timur Taşhan
OBJECTIVE: This study aimed to determine the validity and reliability of the reproductive autonomy scale by adapting it to Turkish society. MATERIALS AND METHODOLOGY: Designed with a methodological method, the study was conducted with an online form created by using Google Forms with 308 married women of reproductive age between the ages of 15 and 49 who use WhatsApp or Instagram. The cultural adaptation process of the scale was carried out in three stages: language validity, content validity, and pilot application...
February 10, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38332458/real-world-study-of-lymphadenectomy-in-patients-with-advanced-epithelial-ovarian-cancer
#29
JOURNAL ARTICLE
Ziran Yin, Ming Wang
BACKGROUND: The evidence on the role of retroperitoneal lymphadenectomy is limited to less common histology subtypes of epithelial advanced ovarian cancer. METHODS: This retrospective cohort study utilized data from the Surveillance, Epidemiology, and End Results Program from January 1, 2010, to December 31, 2019. Patients with stage III-IV epithelial ovarian cancer were included and divided into two groups based on whether they received retroperitoneal lymphadenectomy...
February 8, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38325806/validity-and-reliability-study-of-the-cardiff-fertility-knowledge-scale-in-turkish
#30
JOURNAL ARTICLE
Resmiye Kaya Odabaş, Ayla Ergin, Figen Başkan Birinci
AIM: This study aims to determine the Turkish validity and reliability of the Cardiff Fertility Knowledge Scale. METHODS: This methodological research was conducted between April and December 2022 with 302 married individuals at a health center in Kocaeli province, Turkey. Research data were collected using a Personal Information Form and the Cardiff Fertility Knowledge Scale. Content construct and face validity, item analysis, factor analysis, and internal consistency were used to evaluate the data...
February 7, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38325805/evaluation-of-maternal-serum-thiol-and-ischemia-modified-albumin-levels-in-cases-of-placenta-previa-a-case-control-study-in-a-tertiary-center
#31
JOURNAL ARTICLE
Ramazan Denizli, Atakan Tanacan, Ayşe Gülçin Bastemur, Bedri Sakcak, Nihat Farisogullari, Özgür Kara, Hayriye Gözde Kanmaz Kutman, Salim Neselioglu, Özcan Erel, Dilek Sahin
AIM: We aim to compare the maternal serum thiol and ischemia-modified albumin (IMA) levels between pregnant women with placenta previa and those with uncomplicated pregnancies and to determine whether changes in these levels were useful in predicting cases of abnormally invasive placenta (AIP). METHODS: Fifty-five pregnant women diagnosed with placenta previa according to the diagnostic criteria (case group) were compared to 100 women with uncomplicated pregnancies of similar demographic characteristics (control group)...
February 7, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38316165/consultants-for-the-journal-of-obstetrics-and-gynaecology-research-2023
#32
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
February 5, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38308457/the-efficacy-of-vaginal-treatment-for-non-lactobacillus-dominant-endometrial-microbiota-a-case-control-study
#33
JOURNAL ARTICLE
Mito Sakamoto, Hiroaki Tanaka, Sayako Enomoto, Hiroki Takeuchi, Mikiko Nishioka, Kayo Tanaka, Erina Takayama, Tadashi Maezawa, Eiji Kondo, Tomoaki Ikeda
AIM: Reduced Lactobacillus occupancy in the uterine microflora has been associated with implantation failure. This study aimed to evaluate a treatment for improving the uterine microflora. METHODS: This study included patients diagnosed with repeated implantation failure-defined as failure to achieve pregnancy after two or more transfers of viable embryos-who were classified as non-Lactobacillus dominant. Treatment A comprised oral administration of antibiotics for 1 week, followed by oral probiotic butyrate tablets (3 g/day) for approximately 30 days...
February 2, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38304973/defining-the-relationship-between-ovarian-adult-granulosa-cell-tumors-and-synchronous-endometrial-pathology-does-ovarian-tumor-size-correlate-with-endometrial-cancer
#34
JOURNAL ARTICLE
Abdurrahman Alp Tokalioglu, Okan Oktar, Mustafa Sahin, Cagatayhan Ozturk, Ozgur Erdogan, Hande Esra Koca Yildirim, Yesim Ucar, Fatih Kilic, Burak Ersak, Necim Yalcin, Fatma Ozmen, Aysun Alci, Sevda Bas, Goksen Gorgulu, Ilker Selcuk, Gokhan Ucar, Ozgur Kocak, Caner Cakir, Cigdem Kilic, Gunsu Kimyon Comert, Isin Ureyen, Tayfun Toptas, Mehmet Ali Narin, Tolga Tasci, Salih Taskin, Nurettin Boran, Bulent Ozdal, Muzaffer Sanci, Dogan Uncu, Vakkas Korkmaz, Ozlem Moraloglu Tekin, Yaprak Ustun, Fırat Ortac, Taner Turan
OBJECTIVE: The main feature of adult granulosa cell tumors (AGCT) is their capacity to secrete hormones, with nearly all of them capable of synthesizing oestradiol. The primary goal of this study is to identify synchronized endometrial pathologies, particularly endometrial cancer, in AGCT patients who had undergone a hysterectomy. MATERIALS AND METHODS: The study cohort comprised retrospectively of 316 AGCT patients from 10 tertiary gynecological oncology centers...
February 2, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38297984/neuroendocrine-carcinoma-of-the-uterine-cervix-with-extensive-pagetoid-spread-pattern
#35
Azusa Sakurai, Koji Yamanoi, Ken Yamaguchi, Junzo Hamanishi, Sachiko Minamiguchi, Masaki Mandai
There have been no reported cases of neuroendocrine carcinoma (NEC) of the cervix with pagetoid spread (Pag-S). A 44-year-old woman came to our department because of abnormal cytology that persisted immediately after a radical hysterectomy for NEC of the cervix. A mapping biopsy in a large area from the vaginal wall to the vulva revealed that synaptophysin/Ki-67-positive tumor cells were scattered within the epithelium in multiple areas, suggesting a wide Pag-S of NEC. Because tumor cells were found beyond the vaginal wall, the anterior pelvic exenteration was performed...
January 31, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38281490/efficacy-and-safety-of-vaginal-formulations-with-tyndallized-ferments-in-subjects-with-nonspecific-vulvovaginitis-a-randomized-study-in-italy
#36
JOURNAL ARTICLE
Francesco Forleo, Fanny Mara Pelosi, Luigina Bianco, Vincenzo Petrella
AIM: In this study, we tested the efficacy, safety, and tolerability of vaginal ovules and a vaginal douche containing tyndallized ferments in women affected by nonspecific vulvovaginitis, with or without the human papillomavirus (HPV). METHODS: The study included 91 female patients and had a randomized, controlled sequential design, with parallel groups. Ovules and douche were tested and compared to a control group treated with sterile physiological solution. Total symptom score (TSS), individual signs and symptoms, therapeutic success were evaluated, as well as safety and tolerability...
January 28, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38273716/annual-numbers-of-diagnoses-and-medical-expenses-for-obstetric-diseases-in-japan-a-report-from-the-national-database-of-health-insurance-claims
#37
JOURNAL ARTICLE
Chie Nagata, Maiko Suto, Naho Morisaki, Tohru Kobayashi, Kenji Takehara
AIM: The present study aimed to estimate the total numbers of obstetric diseases diagnosed, total amounts of medical expenses claimed for obstetric diseases, their averages per livebirth, and yearly trends in Japan. METHODS: This is a secondary analysis of the National Database of Health Insurance Claims and Specific Health Checkups of Japan (NDB) (data from 2015 to 2019). The target population was women of reproductive age (15-49 years old) with diseases in pregnancy, childbirth, and the puerperium, defined by having O codes according to the International Classification of Diseases 10th Revision...
January 25, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38263596/survey-on-the-implementation-status-and-reproductive-outcomes-of-oocyte-and-ovarian-tissue-cryopreservation-in-japan-historical-comparison-with-nationwide-surveys
#38
JOURNAL ARTICLE
Seido Takae, Miyuki Harada, Kentaro Nakamura, Sayako Furuyama, Masanori Ono, Yutaka Osuga, Nao Suzuki
PURPOSE: To clarify the reproductive outcomes of fertility preservation (FP) treatment. METHODS: We conducted a mailed-in questionnaire survey at institutions certified by the Japan Society of Obstetrics and Gynecology to investigate the number of oocyte cryopreservations (OC) and ovarian tissue cryopreservations (OTC) performed from December 2016 to the end of 2020. And, we conducted a detailed investigation of cases in which frozen specimens were used during the investigation period, and made historical comparisons with previous nationwide studies...
January 23, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38263573/prenatal-diagnosis-and-appearance-of-nasal-chondromesenchymal-hamartoma-in-a-fetus-a-case-report
#39
Yu-Qing Su, Shu-Jing Huang, Yan-Ting Lin, Mei Huang, Xiao-Dong Zhang, Bi-Mei Zhuang, Jin-Na Jiang, Dong-Yu Bai, Jin-Rong Lin, Yi-Ming Su
We report a case of fetal nasal chondromesenchymal hamartoma (NCMH) first noted on prenatal ultrasound at 34 weeks. A solid-cystic mass which predominantly hyperechoicgenic and relatively clear margin, was located on the left nasal cavity and pharynx, with anterior extension and moderate blood flow. Further follow-up ultrasound examination depicted an enlargement of the tumor. Fetal magnetic resonance imaging (MRI) showed an inhomogeneous signal lesion involving the ethmoid sinuses, nasal cavity, and pharynx...
January 23, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38262424/a-phase-i-ii-study-evaluating-the-pharmacokinetics-pharmacodynamics-and-safety-of-drospirenone-as-an-oral-contraceptive-in-japanese-women
#40
JOURNAL ARTICLE
Kunio Kitamura, Enrico Colli, Rieko Azuma, Ryoko Kikuyama, Masayuki Kanai
AIM: Drospirenone (DRSP) is a synthetic progestogen approved as a progestin-only pill for contraception in both the United States and Europe. Herein, we conducted a phase I/II study to evaluate the pharmacokinetics, pharmacodynamics, and safety of DRSP in Japanese women. METHODS: Single and multiple doses of 4 mg of DRSP were orally administered to healthy premenopausal Japanese women. In the multiple-dose period, 4 mg of DRSP was administered once daily for 24 days...
January 23, 2024: Journal of Obstetrics and Gynaecology Research
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