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Journal of Obstetrics and Gynaecology Research

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https://www.readbyqxmd.com/read/29144016/what-is-the-protective-effect-of-metformin-on-rat-ovary-against-ischemia-reperfusion-injury
#1
Cemile Dayangan Sayan, Gokhan Karaca, Zehra Sema Ozkan, Ozlem B Tulmac, Aslı Ceylan Isik, Tuba Devrim, Gülcin Aydin, Ilkin Yeral
AIM: The aim of this study was to investigate the protective effect of metformin on the rat ovary against ischemia-reperfusion injury. METHODS: Thirty-seven female Wistar albino rats were used in the study. The rats were divided into five groups, as follows: sham operation group (group 1); torsion group (group 2); torsion/detorsion + saline group (group 3); torsion/detorsion + low-dose metformin group (group 4); and torsion/detorsion + high-dose metformin group (group 5)...
November 16, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29144012/uterine-cervical-adenocarcinoma-associated-with-lobular-endocervical-glandular-hyperplasia-radiologic-pathologic-correlation
#2
Ayumi Ohya, Shiho Asaka, Yasunari Fujinaga, Masumi Kadoya
AIM: We aimed to identify the radiologic features of uterine cervical adenocarcinoma associated with lobular endocervical glandular hyperplasia (LEGH). METHODS: We retrospectively analyzed magnetic resonance (MR) images and pathologic findings of eight patients who underwent preoperative MR imaging followed by surgical resection and who were pathologically diagnosed with adenocarcinoma (except for adenocarcinoma in situ) associated with LEGH. We assessed the following MR findings: multicystic component (MC), solid component (SC), signal intensity of SC on diffusion-weighted imaging (DWI) and the apparent diffusion coefficient (ADC) map, and radiological stage (r-stage) based on the FIGO classification...
November 16, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29121434/spontaneous-post-partum-rupture-of-bilateral-ovarian-arteries-treated-with-transarterial-embolization
#3
Rupert Stanborough, Kathleen Hamrick, Christopher Stephens
Rupture of an ovarian artery aneurysm in the peripartum period occurs in both traumatic and atraumatic settings. To our knowledge, this is the first reported case of spontaneous atraumatic rupture of the bilateral ovarian arteries. This report describes a multiparous recently post-partum patient with abdominal pain and signs of hemodynamic compromise, the sequela of hemoperitoneum from ruptured bilateral ovarian arteries. With a multidisciplinary approach, this patient was successfully treated with transarterial embolization...
November 9, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29121433/structural-arrangement-of-vesicouterine-fistula-revisited-an-immunohistochemical-study-documenting-the-presence-of-the-endometrium
#4
Maciej Jóźwik, Marcin Jóźwik, Robert Kozłowski, Stanisław Sulkowski, Andrzej Semczuk, Michał Jóźwik
Previous research has described a woman of reproductive age who presented with a vesicouterine fistula (VUF) of 20 months' duration. The VUF was lined with a metaplastic glandular epithelium containing both estrogen receptors (ER) and progesterone receptors (PR) in abundance. The aim of the present investigation was to evaluate the histology of the VUF canal when exposure to urine of the cellular elements within the fistula was of much shorter duration. A 41-year-old woman who developed a VUF during her third cesarean section was treated with transvesical fistula excision, electrocoagulation, and subsequent attempted hormonal treatment...
November 9, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29121428/efficacy-of-medroxyprogesterone-acetate-treatment-and-retreatment-for-atypical-endometrial-hyperplasia-and-endometrial-cancer
#5
Satoshi Tamauchi, Hiroaki Kajiyama, Fumi Utsumi, Shiro Suzuki, Kaoru Niimi, Jun Sakata, Mika Mizuno, Kiyosumi Shibata, Fumitaka Kikkawa
AIM: Medroxyprogesterone acetate (MPA) is used to preserve fertility in patients with Grade 1 endometrial cancer without myometrial invasion (G1EA) and those with atypical endometrial hyperplasia (AEH). However, the efficacy of retreatment with MPA has not been sufficiently established for patients who experience recurrence but wish to retain their fertility. This study aimed to show the effectiveness of MPA treatment and retreatment for AEH and G1EA. METHODS: A total of 39 patients received MPA treatment between 2005 and 2015, including nine with G1EA and 30 with AEH...
November 9, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29121427/long-term-survival-with-bevacizumab-in-heavily-pretreated-and-platinum-resistant-mucinous-ovarian-cancer-a-case-report
#6
Yosuke Tarumi, Taisuke Mori, Hiroshi Matsushima, Tetsuya Kokabu, Hiroshi Tsuchiya, Jo Kitawaki
The prognosis of patients with recurrent and platinum-resistant ovarian cancer is quite poor. Randomized trials have shown that bevacizumab (BEV) can be effective, even in platinum-resistant ovarian cancer, but only a few such cases of long-term survival with BEV have been reported. Furthermore, there is no consensus on how many cycles of BEV should be administered. Herein, we report a case of refractory mucinous ovarian cancer showing long-term survival after six cycles of weekly paclitaxel with BEV followed by 26 cycles of BEV maintenance...
November 9, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29121417/transabdominal-cerclage-tac-for-patients-with-ultra-short-uterine-cervix-after-uterine-cervix-surgery-and-its-impact-on-pregnancy
#7
Shinichi Ishioka, Miseon Kim, Yuko Mizugaki, Saori Kon, Kyoko Isoyama, Masahito Mizuuchi, Miyuki Morishita, Tsuyoshi Baba, Takao Sekiya, Tsuyoshi Saito
AIM: Patients with an ultra-short uterine cervix as a result of large conization, repeated conization or radical trachelectomy (RT), are at high risk of preterm premature rupture of the membrane, which leads to preterm birth. We have commenced performing transabdominal cerclage (TAC) of the uterine cervix for these patients. In this study, we examined the safety of TAC and its impact on pregnancy. METHODS: We have performed TAC in 11 patients before pregnancy: in six after large cervical operations, such as repeated conization; and in five for difficulties with cervical cerclage after RT...
November 9, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29121416/pregnant-outcomes-of-atypical-polypoid-adenomyoma-treated-with-progestin-therapy
#8
Qin Chen, Weiguo Lu, Bingjian Lu
AIM: We aimed to investigate the long-term clinical and pregnancy outcome in patients with atypical polypoid adenomyoma (APA) after hysteroscopic excision. METHODS: We analyzed the clinicopathological features, including pregnancy outcomes, in 10 APA patients who had been treated with hysteroscopic excision of the lesion and progesterone therapy. RESULTS: The patients were all nulliparous, and nine had been clinically diagnosed as infertile...
November 9, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29114962/annual-report-of-the-perinatology-committee-japan-society-of-obstetrics-and-gynecology-2016-overall-report-on-a-comprehensive-retrospective-study-of-obstetric-management-of-preterm-labor-and-preterm-premature-rupture-of-the-membranes
#9
Hiroshi Sameshima, Shigeru Saito, Yoshio Matsuda, Masato Kamitomo, Shintaro Makino, Masanao Ohashi, Emi Kino, Naohiro Kanayama, Satoru Takeda
We conducted a questionnaire survey on the current obstetric management of preterm labor (PL) and preterm premature rupture of the membranes (pPROM). The questionnaire covered approximately a third of all preterm deliveries and nearly half of the preterm deliveries before 32 gestational weeks. The diagnostic criterion for PL was either painful uterine contractions or cervical dilatation. Tocolytic agents were primarily used as long-term maintenance therapy. Intrauterine infection was clinically diagnosed at most responding institutions...
November 8, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29111594/letter-to-successful-treatment-of-uterine-artery-pseudoaneurysm-with-laparoscopic-temporary-clamping-of-bilateral-uterine-arteries-followed-by-hysteroscopic-surgery-pseudoaneurysm-and-vascular-involution
#10
LETTER
Shigeki Matsubara, Daisuke Matsubara, Hironori Takahashi
No abstract text is available yet for this article.
November 7, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29111579/knowledge-and-perceptions-of-zika-virus-among-reproductive-aged-women-after-public-announcement-of-local-mosquito-borne-transmission
#11
Christine L Curry, Colette Tse, Victoria Billero, Leah Hellerstein, Marisa Messore, Lydia Fein
AIM: This study was conducted to ascertain the knowledge and perceptions of the Zika virus among reproductive-aged women living in the first affected area of the United States with local mosquito-borne transmission. METHODS: Reproductive-aged women were surveyed during the four weeks immediately following the announcement of local Zika virus transmission. The survey evaluated the participant's knowledge of Zika pathogenesis and transmission, sequelae of infection, epidemiology and public health information...
November 7, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29094502/association-between-uterine-position-and-transvaginal-misoprostol-treatment-for-early-pregnancy-failure
#12
Henry H Chill, Nirit Malyanker, Gilad Karavani, Rani Haj-Yahya, Shmuel Herzberg, Raz Bahar, David Shveiky, Uri P Dior
AIM: We aimed to determine the importance of uterine position as a predicting factor of success rate in medically treated early pregnancy failure (EPF). METHODS: We carried out a retrospective cohort study at the Obstetrics and Gynecology Department of a tertiary medical center between January 2011 and June 2012. We included women diagnosed with EPF, which we defined as women diagnosed with missed abortion up to 13 gestational weeks. Patients were treated with one or two doses of 800 μg of misoprostol vaginally in accordance with the department's protocol...
November 2, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29094487/effectiveness-of-fetal-cardiac-screening-for-congenital-heart-disease-using-a-combination-of-the-four-chamber-view-and-three-vessel-view-during-the-second-trimester-scan
#13
Mina Itsukaichi, Takehiro Serikawa, Kosuke Yoshihara, Hiroshi Suzuki, Kazufumi Haino, Masayuki Yamaguchi, Takayuki Enomoto, Koichi Takakuwa
AIM: We aimed to assess the accuracy and effectiveness of fetal cardiac screening for congenital heart disease (CHD) during the second trimester by general obstetricians in a non-selected population. METHODS: In this multicenter, prospective cohort study of fetal cardiac screening, four-chamber and three-vessel views were recorded by obstetricians at 18-21 gestational weeks (GW). A total of 3005 fetuses that were scheduled for delivery at our institution were included...
November 2, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29094486/comparison-of-effacement-curve-with-dilatation-curve-for-prediction-of-labor-progression
#14
Jila Agah, Roya Baghani, Milad Nazarzadeh, Sedigheh Borna
AIM: This study was conducted to evaluate the ability of the effacement curve to predict fetal descent by comparing it to dilatation in order to improve the accuracy of the current partogram. METHOD: We conducted an observational study of women who were admitted for vaginal delivery at Mobini Hospital, Sabzevar, Iran in 2015. During labor, dilatation and effacement were plotted in different graphs and then their association with fetal descent was separately evaluated and compared...
November 2, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29094482/maternal-peripartum-septic-shock-caused-by-intrauterine-infection-with-edwardsiella-tarda-a-case-report-and-review-of-the-literature
#15
Yuki Miyazawa, Keisuke Murakami, Yuichiro Kizaki, Yukiko Itaya, Yasushi Takai, Hiroyuki Seki
Edwardsiella tarda (E. tarda) is a rare pathogen in humans, especially during the peripartum period. Only a few cases of fatal neonatal infection with E. tarda have been reported. Herein, we describe a case of maternal septicemia caused by E. tarda following peripartum chorioamnionitis. The mother developed septic shock, disseminated intravascular coagulation and a post-cesarean wound hematoma with abscess. Her condition improved with multidisciplinary therapy including blood transfusion, antimicrobial agents, recombinant thrombomodulin and surgical debridement...
November 2, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29094453/uterine-metastasis-of-lung-adenocarcinoma-under-molecular-target-therapy-with-epidermal-growth-factor-receptor-tyrosine-kinase-inhibitors-a-case-report-and-review-of-the-literature
#16
Mayu Shibata, Masato Shizu, Kazuko Watanabe, Akihiro Takeda
A 63-year-old woman presented with abnormal vaginal bleeding. Her disease history was significant, and included advanced lung adenocarcinoma with a deletion mutation in exon 19 of the epidermal growth factor receptor (EGFR) gene, which was managed by concurrent chemoradiotherapy, followed by molecular targeted therapy with tyrosine kinase inhibitors (TKIs) for a two-year period. Contrast-enhanced computed tomography showed the enlargement of a previously suspicious myoma node, with peripheral enhancement. Hemorrhagic necrosis was also observed on magnetic resonance imaging...
November 2, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29094444/metformin-as-a-prophylactic-treatment-of-gestational-diabetes-in-pregnant-patients-with-pregestational-insulin-resistance-a-randomized-study
#17
Enrique Valdés, Alvaro Sepúlveda-Martínez, Paula Candia, Nancy Abusada, Rodrigo Orellana, Bárbara Manukian, Eduardo Cuellar
AIM: We aimed to assess the use of metformin (MTF) in the prevention of gestational diabetes mellitus (GDM) in patients with pregestational insulin resistance (PIR). METHODS: A double blind, multicenter, randomized trial was carried out in patients with a history of PIR and pregestational MTF treatment. Groups were allocated either to MTF 1700 mg/day or placebo. Patients were recruited between 12(+0) and 15(+6)  gestational weeks, and treatment was extended until week 36...
November 2, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29094433/effects-of-vitamin-d-supplementation-on-insulin-sensitivity-and-androgen-levels-in-vitamin-d-deficient-polycystic-ovary-syndrome-patients
#18
Cihan Karadağ, Tevfik Yoldemir, Dilek Gogas Yavuz
AIM: The aim of this study was to identify the effects of vitamin D supplementation on insulin sensitivity and androgen levels in vitamin-D-deficient polycystic ovary syndrome (PCOS) patients. METHODS: Sixty-seven vitamin-D-deficient (25-hydroxyvitamin D [25(OH)D] levels below 20 ng/mL) PCOS patients and 54 vitamin-D-deficient non-PCOS volunteer subjects matched for age and body mass index were enrolled to this prospective study. All participants were given 50 000 IU/week cholecalciferol orally for 8 weeks and 1500 IU/day for 4 weeks...
November 2, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29094431/rate-of-intrapartum-cesarean-section-and-related-factors-in-older-nulliparous-women-at-term
#19
Haruka Muto, Keisuke Ishii, Takahiro Nakano, Shusaku Hayashi, Yoko Okamoto, Nobuaki Mitsuda
AIM: The aim of this study was to determine the effect of maternal age on emergency cesarean section (CS) during labor, and to identify the independent risk factors for emergency CS. METHODS: This was a retrospective cohort study using data from 2009 to 2014 from a tertiary perinatal care center in Japan. Inclusion criteria were maternal age ≥ 35 years, nulliparous singleton pregnancy at term and a cephalic presentation without indication of elective CS at onset of labor...
November 2, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29094429/cesarean-section-rates-and-local-resources-for-perinatal-care-in-japan-a-nationwide-ecological-study-using-the-national-database-of-health-insurance-claims
#20
Eri Maeda, Osamu Ishihara, Jun Tomio, Aya Sato, Yukihiro Terada, Yasuki Kobayashi, Katsuyuki Murata
AIM: High cesarean section (CS) rates in middle and high-income countries are partly attributable to provider factors, such as staffing patterns and fear of litigation. However, the relationship between CS rates and healthcare resources in the community is poorly understood. Official data on CS rates has been particularly limited in Japan. In this study, we examined nationwide CS statistics and evaluated the association with local resources for perinatal care. METHODS: We used accumulated data for CS registered in the Japan National Database of health insurance claims in 2013 and calculated crude and age-standardized CS rates at national and prefectural levels...
November 2, 2017: Journal of Obstetrics and Gynaecology Research
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