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Heart Failure Reviews

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https://www.readbyqxmd.com/read/30209643/clinical-outcome-of-left-ventricular-multipoint-pacing-versus-conventional-biventricular-pacing-in-cardiac-resynchronization-therapy-a-systematic-review-and-meta-analysis
#1
REVIEW
Feng Hu, Lihui Zheng, Ligang Ding, Zhongpeng Du, Erpeng Liang, Lingmin Wu, Gang Chen, Xiaohan Fan, Yan Yao, Yu Jiang
Cardiac resynchronization therapy (CRT) is an effective treatment for selected patients with systolic heart failure. Unlike conventional biventricular pacing (BIP), the left ventricular multipoint pacing (MPP) can increase the number of left ventricular pacing sites via a quadripolar lead positioned in the coronary sinus. This synthetic study was conducted to integratively and quantitatively evaluate the clinical outcome of MPP in comparison with BIP. We systematically searched the databases of EMBASE, Ovid medline, and Cochrane Library through May 2018 for studies comparing the clinical outcome of MPP with BIP in the patients who accepted CRT...
September 12, 2018: Heart Failure Reviews
https://www.readbyqxmd.com/read/30194516/loop-diuretics-in-chronic-heart-failure-how-to-manage-congestion
#2
REVIEW
Justas Simonavičius, Christian Knackstedt, Hans-Peter Brunner-La Rocca
Loop diuretics remain the cornerstone of congestion management in contemporary chronic heart failure care. However, their use is not supported by high quality data, and there is doubt about the safety in the outpatient heart failure setting. Still, congestion is related to a worse outcome, and there is general consensus among experts that congestion should not be tolerated in heart failure patients. Recommendations in international guidelines, regarding decongestion strategies in chronic heart failure, are limited...
September 7, 2018: Heart Failure Reviews
https://www.readbyqxmd.com/read/30167929/lanosteryl-triterpenes-from-protorhus-longifolia-as-a-cardioprotective-agent-a-mini-review
#3
REVIEW
Nonhlakanipho F Sangweni, Phiwayinkosi V Dludla, Rebamang A Mosa, Abidemi P Kappo, Andy Opoku, Christo J F Muller, Rabia Johnson
The epidemic of cardiovascular diseases is a global phenomenon that is exaggerated by the growing prevalence of diabetes mellitus. Coronary artery disease and diabetic cardiomyopathy are the major cardiovascular complications responsible for exacerbated myocardial infarction in diabetic individuals. Increasing research has identified hyperglycemia and hyperlipidemia as key factors driving the augmentation of oxidative stress and a pro-inflammatory response that usually results in increased fibrosis and reduced cardiac efficiency...
August 31, 2018: Heart Failure Reviews
https://www.readbyqxmd.com/read/30143910/understanding-non-response-to-cardiac-resynchronisation-therapy-common-problems-and-potential-solutions
#4
REVIEW
Benjamin J Sieniewicz, Justin Gould, Bradley Porter, Baldeep S Sidhu, Thomas Teall, Jessica Webb, Gerarld Carr-White, Christopher A Rinaldi
Heart failure is a complex clinical syndrome associated with a significant morbidity and mortality burden. Reductions in left ventricular (LV) function trigger adaptive mechanisms, leading to structural changes within the LV and the potential development of dyssynchronous ventricular activation. This is the substrate targeted during cardiac resynchronisation therapy (CRT); however, around 30-50% of patients do not experience benefit from this treatment. Non-response occurs as a result of pre-implant, peri-implant and post implant factors but the technical constraints of traditional, transvenous epicardial CRT mean they can be challenging to overcome...
August 24, 2018: Heart Failure Reviews
https://www.readbyqxmd.com/read/30099646/electrical-manipulation-of-the-failing-heart
#5
REVIEW
Valerio Zacà, Theodore Murphy, Mauro Biffi
Chronic heart failure with reduced (≤ 40%) ejection fraction (HFrEF) poses a significant residual mortality risk despite modern optimal medical therapy. In the last decades, we have witnessed the introduction of breakthrough cardiac implantable electronic devices (CIED) aimed at addressing sudden cardiac death and HF progression in patients with HFrEF, leading to improved survival and functional capacity. Following their introduction, implantable cardioverter defibrillators (ICD) and cardiac resynchronization therapy (CRT) have undergone substantial technological improvements and have been investigated in different settings of HFrEF, some of which yielded controversial results...
August 11, 2018: Heart Failure Reviews
https://www.readbyqxmd.com/read/30094532/transcatheter-aortic-valve-replacement-in-patients-with-severe-aortic-stenosis-and-heart-failure
#6
REVIEW
Chirag Bavishi, Dhaval Kolte, Paul C Gordon, J Dawn Abbott
Severe aortic stenosis (AS) and heart failure (HF) represent an important and high-risk group of patients who are often referred for transcatheter aortic valve replacement (TAVR) due to high risk for surgical intervention. Thus far, randomized controlled trials have shown comparable outcomes between TAVR and surgical aortic valve replacement in patients with severe AS and heart failure with reduced ejection fraction. In the current review, we will discuss (1) the pathophysiology of HF in patients with severe AS, (2) role of imaging modalities in management, (3) role of biomarkers of HF on prognosis, (4) impact of other valvular heart diseases, (5) evidence from the contemporary trials on the role of TAVR in patients with severe AS and HF, and (6) future directions and research...
August 9, 2018: Heart Failure Reviews
https://www.readbyqxmd.com/read/30073443/cardio-oncology-a-new-and-developing-sector-of-research-and-therapy-in-the-field-of-cardiology
#7
REVIEW
Peggy M Kostakou, Nikos T Kouris, Vassilios S Kostopoulos, Dimitrios S Damaskos, Christoforos D Olympios
Cardio-oncology is a new field of interest in cardiology that focuses on the detection, monitoring, and treatment of cardiovascular disease occurring as a side effect of chemotherapy and radiotherapy. Both cancer treatment modalities can cause cardiac dysfunction, a major cause of morbidity and mortality in the oncologic population. It is necessary to periodically monitor cancer patients under treatment, especially those receiving anthracyclines and trastuzumab (monoclonal antibody), using mainly 3D echocardiography to calculate left ventricular ejection fraction and to estimate myocardial deformation...
August 2, 2018: Heart Failure Reviews
https://www.readbyqxmd.com/read/30058016/autonomic-nervous-system-in-takotsubo-syndrome
#8
REVIEW
Sonia Borodzicz, Katarzyna Czarzasta, Grzegorz Opolski, Agnieszka Cudnoch-Jędrzejewska
Takotsubo syndrome (TTS) is an acute and usually reversible heart failure syndrome with symptoms resembling acute myocardial infarction, however, without obstruction of coronary arteries. In the majority of cases, TTS is preceded by emotional or physical stress and the disease concerns mainly postmenopausal women. Although several hypotheses have been introduced, the pathogenesis of TTS is controversial and still remains to be determined. As reported in recent studies, the role of the autonomic nervous system (ANS) seems to be pivotal in the pathogenesis of TTS...
July 30, 2018: Heart Failure Reviews
https://www.readbyqxmd.com/read/30058015/percutaneous-support-of-the-failing-left-and-right-ventricle-recommendations-for-the-use-of-mechanical-device-therapy
#9
REVIEW
Sven Möbius-Winkler, Michael Fritzenwanger, Rüdiger Pfeifer, P Christian Schulze
Patients in cardiogenic shock and acute heart failure show high mortality and morbidity despite aggressive and invasive methods such as percutaneous coronary intervention and the use of mechanical support devices. Percutaneous implantation of active hemodynamic support is often the only option for hemodynamic stabilization of patients in cardiogenic shock. Therefore, current guidelines support the use of these devices. Standardized protocols and clinical algorithms for the use of these support devices decrease mortality in these patients...
July 30, 2018: Heart Failure Reviews
https://www.readbyqxmd.com/read/30033478/diagnostic-and-prognostic-role-of-cardiac-magnetic-resonance-in-acute-myocarditis
#10
REVIEW
Chrysanthos Grigoratos, Gianluca Di Bella, Giovanni Donato Aquaro
Acute myocarditis (AM) is commonly found in everyday clinical practice. Differential diagnosis between various causes of myocardial damage with non-obstructive coronary arteries can be cumbersome for clinician. Moreover, AM may be provoked by a number of different causes and clinical presentation can be heterogeneous with potential overlap going from asymptomatic or subclinical to severe heart failure, arrhythmias, and death. Cardiac magnetic resonance (CMR) over the last decades has proven to be the diagnostic technique of choice since it allows identifying AM with excellent diagnostic accuracy...
July 23, 2018: Heart Failure Reviews
https://www.readbyqxmd.com/read/30054781/continuous-versus-intermittent-administration-of-furosemide-in-acute-decompensated-heart-failure-a-systematic-review-and-meta-analysis
#11
REVIEW
Akira Kuriyama, Seigo Urushidani
Diuretic therapy is important in critically ill patients because fluid overload impairs organ function and increases mortality. Compared to intermittent administration, continuous infusion of loop diuretics is theoretically superior in terms of diuresis and electrolyte balance. However, the available evidence is susceptible to carryover diuretic effects and resistance in earlier crossover trials. Consequently, we conducted a systematic review and meta-analysis of parallel-group randomized controlled trials to compare these two strategies in adults with acute decompensated heart failure...
July 21, 2018: Heart Failure Reviews
https://www.readbyqxmd.com/read/29995216/flow-mediated-dilation-and-heart-failure-a-review-with-implications-to-physical-rehabilitation
#12
REVIEW
G P T Areas, A Mazzuco, F R Caruso, R B Jaenisch, R Cabiddu, S A Phillips, R Arena, A Borghi-Silva
Endothelial dysfunction plays as an important role on mismatch responses that occur during exercise in patients with congestive heart failure (CHF). However, cardiac rehabilitation, a core component of management of CHF patients, can improve endothelial function, contributing to reduce the morbidity and mortality of these patients. The primary aims of this review were to describe the importance of flow-mediated dilatation (FMD) as a non-invasive validation tool to assess endothelial dysfunction and to highlight the relevance of scientific studies that evaluated the effects of exercise interventions on peripheral vascular endothelial function as measured by FMD in patients with CHF with both preserved and reduced ejection fraction...
July 11, 2018: Heart Failure Reviews
https://www.readbyqxmd.com/read/29987445/biomarkers-for-the-identification-of-cardiac-fibroblast-and-myofibroblast-cells
#13
REVIEW
Emiri Tarbit, Indu Singh, Jason N Peart, Roselyn B Rose'Meyer
Experimental research has recognized the importance of cardiac fibroblast and myofibroblast cells in heart repair and function. In a normal healthy heart, the cardiac fibroblast plays a central role in the structural, electrical, and chemical aspects within the heart. Interestingly, the transformation of cardiac fibroblast cells to cardiac myofibroblast cells is suspected to play a vital part in the development of heart failure. The ability to differentiate between the two cells types has been a challenge. Myofibroblast cells are only expressed in the stressed or failing heart, so a better understanding of cell function may identify therapies that aid repair of the damaged heart...
July 10, 2018: Heart Failure Reviews
https://www.readbyqxmd.com/read/29968222/response-to-the-editor
#14
LETTER
Anne Pernille Ofstad, Dan Atar, Lars Gullestad, Gisle Langslet, Odd Erik Johansen
No abstract text is available yet for this article.
July 2, 2018: Heart Failure Reviews
https://www.readbyqxmd.com/read/29968221/cardiac-resynchronization-therapy-improves-left-ventricular-remodeling-and-function-compared-with-right-ventricular-pacing-in-patients-with-atrioventricular-block
#15
REVIEW
Dasheng Lu, Hao Zhang, Hongxiang Zhang
Right ventricular pacing (RVP) exerts a detrimental effect on left ventricular (LV) remodeling. In patients with atrioventricular block (AVB) that require ventricular pacing, the effect of biventricular pacing (BiVP) versus RVP on LV remodeling and function has not been comprehensively assessed in a meta-analysis. Electric databases MEDLINE and Cochrane Library were retrieved for randomized controlled trials (RCT) comparing RVP and BiVP in patients with AVB. Data on left ventricular ejection fraction (LVEF) and LV volumes were analyzed, stratified by different time points...
July 2, 2018: Heart Failure Reviews
https://www.readbyqxmd.com/read/30043131/author-s-response-to-letter-to-the-editor
#16
LETTER
Anne Pernille Ofstad, Dan Atar, Lars Gullestad, Gisle Langslet, Odd Erik Johansen
No abstract text is available yet for this article.
September 2018: Heart Failure Reviews
https://www.readbyqxmd.com/read/29982970/letter-to-the-editor-regarding-the-article-the-heart-failure-burden-of-type-2-diabetes-mellitus-a-review-of-pathophysiology-and-interventions
#17
LETTER
Michael Dandel, Gerd Wallukat, Roland Hetzer
No abstract text is available yet for this article.
September 2018: Heart Failure Reviews
https://www.readbyqxmd.com/read/29978359/testosterone-myocardial-function-and-mortality
#18
REVIEW
Vittorio Emanuele Bianchi
The cardiovascular system is particularly sensitive to androgens, but some controversies exist regarding the effect of testosterone on the heart. While among anabolic abusers, cases of sudden cardiac death have been described, recently it was reported that low serum level of testosterone was correlated with increased risk of cardiovascular diseases (CVD) and mortality rate. This review aims to evaluate the effect of testosterone on myocardial tissue function, coronary artery disease (CAD), and death. Low testosterone level is associated with increased incidence of CAD and mortality...
September 2018: Heart Failure Reviews
https://www.readbyqxmd.com/read/29968223/prognostic-value-of-t1-mapping-and-extracellular-volume-fraction-in-cardiovascular-disease-a-systematic-review-and-meta-analysis
#19
REVIEW
Baiyan Zhuang, Arlene Sirajuddin, Shuli Wang, Andrew Arai, Shihua Zhao, Minjie Lu
T1 mapping and extracellular volume (ECV) fraction are useful new magnetic resonance imaging (MRI) techniques to evaluate myocardial fibrosis; however, their prognostic value has not been well described. In this study, a systematic review and meta-analysis evaluating the prognostic value of these techniques is performed in patients with ischemic and non-ischemic cardiomyopathy. PubMed, Cochrane CENTRAL, and Meta-Register of Controlled Trials were searched for studies that utilized T1 mapping and ECV and that also had ≥ 12 months of follow-up data...
September 2018: Heart Failure Reviews
https://www.readbyqxmd.com/read/29862462/role-of-cytokines-and-inflammation-in-heart-function-during-health-and-disease
#20
REVIEW
Monika Bartekova, Jana Radosinska, Marek Jelemensky, Naranjan S Dhalla
By virtue of their actions on NF-κB, an inflammatory nuclear transcription factor, various cytokines have been documented to play important regulatory roles in determining cardiac function under both physiological and pathophysiological conditions. Several cytokines including TNF-α, TGF-β, and different interleukins such as IL-1 IL-4, IL-6, IL-8, and IL-18 are involved in the development of various inflammatory cardiac pathologies, namely ischemic heart disease, myocardial infarction, heart failure, and cardiomyopathies...
September 2018: Heart Failure Reviews
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