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Vascular Medicine

George M DeKornfeld, Julia Boll, Kenneth R Ziegler, Jonathan Ratcliff, Thomas C Naslund, C Louis Garrard, R James Valentine, John A Curci
An embolic event originating from thrombus on an otherwise un-diseased or minimally diseased proximal artery (Phantom Thrombus) is a rare but significant clinical challenge. All patients from a single center with an imaging defined luminal thrombus with a focal mural attachment site on an artery were evaluated retrospectively. We excluded all patients with underlying anatomic abnormalities of the vessel at the attachment site. Six patients with a mean age of 62.5 years were identified over a 2.5-year period...
August 19, 2018: Vascular Medicine
Ellen K Brinza, Ehrin J Armstrong
Peripheral artery disease (PAD) affects a growing number of women, with a prevalence equal to that of men. Still, little is known about sex-specific differences in disease manifestations of PAD and how these differences in presentation impact outcomes of surgical and endovascular intervention. Women have also been consistently underrepresented in clinical trials evaluating treatment options for vascular disease. Thus, many of the practice guidelines in place today were generated from clinical trial data that either included a small number of women or excluded them entirely, and, consequently, whose findings may not be applicable to female patients...
August 16, 2018: Vascular Medicine
Rebecca J Wellman, Su Bin Cho, Pratibha Singh, Miriya Tune, Carlos A Pardo, Anne M Comi
No abstract text is available yet for this article.
August 16, 2018: Vascular Medicine
Andrew F Prouse, Paula Langner, Mary E Plomondon, P Michael Ho, Javier A Valle, Anna E Barón, Ehrin J Armstrong, Stephen W Waldo
Lower extremity arterial thromboembolism is associated with significant morbidity and mortality. We sought to establish temporal trends in the incidence, management and outcomes of lower extremity arterial thromboembolism within the Veterans Affairs Healthcare System (VAHS). We identified patients admitted to VAHS between 2003 and 2014 with a primary diagnosis of lower extremity arterial thromboembolism. Medical and procedural management were ascertained from pharmaceutical and administrative data. Subsequent rates of major adverse limb events (MALE), major adverse cardiovascular events (MACE), and mortality were calculated using Cox proportional hazards models...
August 14, 2018: Vascular Medicine
GuangMing Tan, Ari J Mintz, Bruce Mintz, Jorge C Borges, Mary Deborah Hines, Robert M Schainfeld, Michael R Jaff, Ido Weinberg
Amphetamine and its related derivatives and analogues (ADRA) are highly addictive central nervous system stimulants that are used commonly in the treatment of attention-deficit/hyperactivity disorder and narcolepsy. These medications are associated with many side effects but reports of peripheral arterial manifestations associated with ADRA usage are scarce. We retrospectively reviewed the records of 16 patients (median age 37 years (IQR 31-47), 13 females) referred to a single tertiary referral service while receiving ADRA...
August 14, 2018: Vascular Medicine
Umberto G Rossi, Anna Maria Ierardi, Gianpaolo Carrafiello, Maurizio Cariati
No abstract text is available yet for this article.
July 1, 2018: Vascular Medicine
Jeffrey S Berger, Beth L Abramson, Renato D Lopes, Gretchen Heizer, Frank W Rockhold, Iris Baumgartner, F Gerry R Fowkes, Peter Held, Brian G Katona, Lars Norgren, W Schuyler Jones, Marcus Millegård, Juuso Blomster, Craig Reist, William R Hiatt, Manesh R Patel, Kenneth W Mahaffey
Patients with peripheral artery disease (PAD) are at heightened risk of cardiovascular morbidity and mortality. We sought to evaluate the risk of concomitant coronary artery disease (CAD) in patients with symptomatic PAD versus PAD without diagnosed CAD, and whether ticagrelor was superior to clopidogrel in reducing that risk. The EUCLID trial randomized 13,885 patients with PAD to antithrombotic monotherapy with ticagrelor or clopidogrel. CAD was defined as prior myocardial infarction (MI), percutaneous coronary intervention (PCI), or coronary artery bypass graft (CABG) surgery...
July 1, 2018: Vascular Medicine
Aaron W Aday, Scott Kinlay, Marie D Gerhard-Herman
Although the resting ankle-brachial index (ABI) is commonly used as a tool to diagnose peripheral artery disease (PAD), several additional indices measured after exercise may have increased sensitivity for identifying PAD. The aim of this study was to determine the utility of resting ABI and three post-exercise physiological parameters for diagnosing PAD confirmed by arterial imaging studies. For each qualifying study, we assessed the performance measures for identifying PAD for resting ABI < 0.90, exercise ABI < 0...
July 1, 2018: Vascular Medicine
Raghu Kolluri, Elizabeth V Ratchford
No abstract text is available yet for this article.
October 2018: Vascular Medicine
Robert P Liddell, Natalie S Evans
No abstract text is available yet for this article.
October 2018: Vascular Medicine
Timothy C Lin, Brittany N Burton, Andrew Barleben, Martin Hoenigl, Rodney A Gabriel
The primary objectives of this work were: (1) to describe trends in HIV prevalence among those undergoing carotid intervention (carotid endarterectomy or carotid artery stenting) in the United States; and (2) to determine if HIV infection is independently associated with symptomatic carotid atherosclerotic disease or age at the time of carotid intervention. In a nationally representative inpatient database from 2004 to 2014, HIV infection was associated with younger age at the time of carotid intervention (59 years [SE 0...
October 2018: Vascular Medicine
Chris T Longenecker
No abstract text is available yet for this article.
October 2018: Vascular Medicine
Natalie Vm Hernandez, Joel L Ramirez, Sukaynah A Khetani, Kimberly A Spaulding, Warren J Gasper, Jade Hiramoto, Daniel Lindqvist, Owen M Wolkowitz, Nancy K Hills, S Marlene Grenon, Greg J Zahner
The present study examines the association between depressive symptoms and inflammatory markers in peripheral artery disease (PAD) to better understand the mechanistic relationship between depression and PAD. A cross-sectional sample of 117 patients with PAD (97% male, 76% Caucasian) was recruited from the San Francisco Veterans Affairs Medical Center. Patients were categorized into three subgroups based upon current depressive symptom severity, as defined by Patient Health Questionnaire-8 scores: no symptoms (score of 0-4, n = 62), mild symptoms (score of 5-9, n = 33), and moderate/severe symptoms (score ≥ 10, n = 22)...
October 2018: Vascular Medicine
Heather L Gornik
No abstract text is available yet for this article.
October 2018: Vascular Medicine
Klaas Frederik Franzen, Johannes Willig, Silja Cayo Talavera, Moritz Meusel, Friedhelm Sayk, Michael Reppel, Klaus Dalhoff, Kai Mortensen, Daniel Droemann
The introduction of electronic cigarettes has led to widespread discussion on the cardiovascular risks compared to conventional smoking. We therefore conducted a randomized cross-over study of the acute use of three tobacco products, including a control group using a nicotine-free liquid. Fifteen active smokers were studied during and after smoking either a cigarette or an electronic cigarette with or without nicotine (eGo-T CE4 vaporizer). Subjects were blinded to the nicotine content of the electronic cigarette and were followed up for 2 hours after smoking a cigarette or vaping an electronic cigarette...
October 2018: Vascular Medicine
Jessica L Fetterman, Naomi M Hamburg
No abstract text is available yet for this article.
October 2018: Vascular Medicine
Leili Pourafkari, Catherine Choi, Reza Garajehdaghi, Arezou Tajlil, Hasan H Dosluoglu, Nader D Nader
The neutrophil-lymphocyte ratio (NLR), as a marker of inflammation, is associated with the severity of peripheral artery disease (PAD). The role of the NLR on predicting future complications after elective revascularization for patients with PAD remains unknown. We aimed to examine the role of the NLR in the development of major adverse limb events (MALE) and the long-term mortality of these patients. We evaluated 1708 revascularization procedures from May 2001 to December 2015 at the Veterans Affairs Western New York Healthcare System from a prospectively maintained vascular database that included demographics, comorbidities and pre-procedural medications...
October 2018: Vascular Medicine
Teresa Martin-Gonzalez, Graeme Penney, Debra Chong, Meryl Davis, Tara M Mastracci
Fusion imaging is standard for the endovascular treatment of complex aortic aneurysms, but its role in follow up has not been explored. A critical issue is renal function deterioration over time. Renal volume has been used as a marker of renal impairment; however, it is not reproducible and remains a complex and resource-intensive procedure. The aim of this study is to determine the accuracy of a fusion-based software to automatically calculate the renal volume changes during follow up. In this study, computerized tomography (CT) scans of 16 patients who underwent complex aortic endovascular repair were analysed...
October 2018: Vascular Medicine
Kim G Smolderen, Mary E Plomondon, Ehrin J Armstrong, Edward Hess, Stephen Waldo, Thomas T Tsai, Thomas M Maddox
The association between depression and peripheral artery disease (PAD) outcomes remains widely understudied. In patients with PAD undergoing a peripheral vascular intervention (PVI) who have a recent diagnosis of depression, it is unknown what their long-term outcomes are and what factors may mediate an adverse risk. We therefore studied 797 consecutive patients undergoing PVI across 33 Veterans Affairs (VA) centers. Depression and outcomes were documented from patients' medical records. Outcomes included: (1) all-cause death; (2) non-fatal cardiovascular events (myocardial infarction, stroke); and (3) PAD-related events (including repeat PVI or amputation)...
October 2018: Vascular Medicine
Joel L Ramirez, Laura M Drudi, S Marlene Grenon
The incidence of depression has been rising rapidly, and depression has been recognized as one of the world's leading causes of disability. More recently, depression has been associated with an increased risk of symptomatic atherosclerotic disease as well as worse perioperative outcomes in patients with cardiovascular disease. Additionally, recent studies have demonstrated an association between depression and peripheral artery disease (PAD), which has been estimated to affect more than 200 million people worldwide...
October 2018: Vascular Medicine
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