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Vascular Medicine

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https://www.readbyqxmd.com/read/29786477/the-impact-of-a-multi-specialty-team-for-high-risk-pulmonary-embolism-on-resident-and-fellow-education
#1
Ayman Elbadawi, Colin Wright, Dhwani Patel, Yu Lin Chen, Justin Mazzillo, Pamela Cameron, Geoffrey D Barnes, Scott J Cameron
The impact of the Pulmonary Embolism Response Team (PERT) model on trainee physician education and autonomy over the management of high risk pulmonary embolism (PE) is unknown. A resident and fellow questionnaire was administered 1 year after PERT implementation. A total of 122 physicians were surveyed, and 73 responded. Even after 12 months of interacting with the PERT consultative service, and having formal instruction in high risk PE management, 51% and 49% of respondents underestimated the true 3-month mortality for sub-massive and massive PE, respectively, and 44% were unaware of a common physical exam finding in patients with PE...
May 1, 2018: Vascular Medicine
https://www.readbyqxmd.com/read/29781402/life-expectancy-and-comorbidities-in-patients-with-hereditary-hemorrhagic-telangiectasia
#2
Freya Droege, Kruthika Thangavelu, Boris A Stuck, Andreas Stang, Stephan Lang, Urban Geisthoff
There are only a few published studies that demonstrate associations between life expectancy, severe comorbidities, and their complications in patients with hereditary hemorrhagic telangiectasia (HHT). Relatives of 73 deceased patients with suspected HHT completed a questionnaire about causes of death, and symptoms and comorbidities that the patients had developed. We compared the data for 55 cases where HHT had been clinically confirmed with the general population. Patients suffering from HHT lost, on average, 19 years (SD 11 years) of potential life compared to the general population...
May 1, 2018: Vascular Medicine
https://www.readbyqxmd.com/read/29781388/hospitalization-metrics-associated-with-hospital-level-variation-in-inferior-vena-cava-filter-utilization-for-patients-with-venous-thromboembolism-in-the-united-states-implications-for-quality-of-care
#3
Ming Chen, Amie Goodin, Hong Xiao, Qiong Han, Driss Raissi, Joshua Brown
Variation in the use of inferior vena cava filters (IVCFs) across hospitals has been observed, suggesting differences in quality of care. Hospitalization metrics associated with venous thromboembolism (VTE) patients have not been compared based on IVCF utilization rates using a national sample. We conducted a descriptive retrospective study using the Nationwide Readmissions Database (NRD) to delineate the variability of hospitalization metrics across the hospital quartiles of IVCF utilization for VTE patients...
May 1, 2018: Vascular Medicine
https://www.readbyqxmd.com/read/29775172/septic-and-tumor-thrombosis-caught-by-inferior-vena-cava-filters-and-demonstrated-on-fdg-pet-ct
#4
Yiyan Liu
No abstract text is available yet for this article.
May 1, 2018: Vascular Medicine
https://www.readbyqxmd.com/read/29775165/a-case-of-horner-s-syndrome-after-catheter-based-fibrinolysis-for-pulmonary-embolism
#5
Julia Loewenthal, Ankit Patel, Robert Kurtz, Gregory Piazza
No abstract text is available yet for this article.
May 1, 2018: Vascular Medicine
https://www.readbyqxmd.com/read/29734865/peripheral-artery-disease-calf-skeletal-muscle-mitochondrial-dna-copy-number-and-functional-performance
#6
Mary M McDermott, Charlotte A Peterson, Robert Sufit, Luigi Ferrucci, Jack M Guralnik, Melina R Kibbe, Tamar S Polonsky, Lu Tian, Michael H Criqui, Lihui Zhao, James H Stein, Lingyu Li, Christiaan Leeuwenburgh
In people without lower extremity peripheral artery disease (PAD), mitochondrial DNA copy number declines with aging, and this decline is associated with declines in mitochondrial activity and functional performance. However, whether lower extremity ischemia is associated with lower mitochondrial DNA copy number and whether mitochondrial DNA copy number is associated with the degree of functional impairment in people with PAD is unknown. In people with and without PAD, age 65 years and older, we studied associations of the ankle-brachial index (ABI) with mitochondrial DNA copy number and associations of mitochondrial DNA copy number with functional impairment...
May 1, 2018: Vascular Medicine
https://www.readbyqxmd.com/read/29734862/great-debates-in-vascular-medicine-extended-duration-anticoagulation-for-unprovoked-venous-thromboembolism-coming-to-consensus-when-the-debate-rages-on
#7
Yogendra Kanthi, Gregory Piazza
No abstract text is available yet for this article.
May 1, 2018: Vascular Medicine
https://www.readbyqxmd.com/read/29683088/increase-in-skin-perfusion-pressure-predicts-amputation-free-survival-after-lower-extremity-bypass-surgery-for-critical-limb-ischemia
#8
Kota Yamamoto, Takuya Kawahara, Atsushi Akai, Toshihiko Isaji, Daisuke Akagi, Takuya Miyahara, Katsuyuki Hoshina
The objective of this study was to determine how postoperative skin perfusion pressure (SPP) as a measure of blood flow after revascularization affects limb prognosis in patients with critical limb ischemia (CLI). We retrospectively reviewed 223 consecutive bypass surgery cases performed in 192 patients with CLI during a 10-year period. SPP was measured 1-2 weeks before and after the procedure. An SPP of 40 mmHg was set as the cut-off value for revascularization. Patients were grouped according to their postoperative SPPs, and amputation-free survival (AFS) was analyzed...
April 1, 2018: Vascular Medicine
https://www.readbyqxmd.com/read/29683087/resolving-the-high-stakes-of-limb-salvage-with-skin-perfusion-pressure
#9
Matthew C Bunte, Mehdi H Shishehbor
No abstract text is available yet for this article.
April 1, 2018: Vascular Medicine
https://www.readbyqxmd.com/read/29671381/minimal-clinically-important-differences-in-treadmill-6-minute-walk-and-patient-based-outcomes-following-supervised-and-home-based-exercise-in-peripheral-artery-disease
#10
Andrew W Gardner, Polly S Montgomery, Ming Wang
We estimated minimal clinically important differences (MCIDs) for small, moderate, and large changes in measures obtained from a standardized treadmill test, a 6-minute walk test, and patient-based outcomes following supervised and home-based exercise programs in symptomatic patients with peripheral artery disease (PAD). Patients were randomized to either 12 weeks of a supervised exercise program ( n=60), a home-based exercise program ( n=60), or an attention-control group ( n=60). Using the distribution-based method to determine MCIDs, the MCIDs for small, moderate, and large changes in peak walking time (PWT) in the supervised exercise group were 38, 95, and 152 seconds, respectively, and the changes in claudication onset time (COT) were 35, 87, and 138 seconds...
April 1, 2018: Vascular Medicine
https://www.readbyqxmd.com/read/29651931/hypertension
#11
Shireen R Khoury, Elizabeth V Ratchford
No abstract text is available yet for this article.
April 1, 2018: Vascular Medicine
https://www.readbyqxmd.com/read/29638194/the-role-of-novel-cytokines-in-inflammation-defining-peripheral-artery-disease-among-patients-with-coronary-artery-disease
#12
Demet Ozkaramanli Gur, Savas Guzel, Aydin Akyuz, Seref Alpsoy, Niyazi Guler
Coronary artery disease (CAD) patients with concomitant peripheral artery disease (PAD) experience more extensive and calcified atherosclerosis, greater lesion progression and more common coronary events compared to patients with CAD only. To characterize the distinct features of this aggressive atherosclerotic disease, we studied novel cytokines that code different stages of atherogenesis. One hundred and eighty consecutive subjects (60 patients into each group of CAD+PAD, CAD and controls) were recruited among patients with stable angina pectoris scheduled for coronary angiography...
April 1, 2018: Vascular Medicine
https://www.readbyqxmd.com/read/29629845/ticagrelor-in-peripheral-artery-disease-endovascular-revascularization-ti-pad-challenges-in-clinical-trial-execution
#13
R Kevin Rogers, William R Hiatt, Manesh R Patel, Mehdi H Shishehbor, Robin White, Naeem D Khan, Narinder P Bhalla, W Schuyler Jones, Cecilia C Low Wang
There is limited evidence to guide clinical decision-making for antiplatelet therapy in peripheral artery disease (PAD) in the setting of lower extremity endovascular treatment. The Ticagrelor in Peripheral Artery Disease Endovascular Revascularization Study (TI-PAD) evaluated the role of ticagrelor versus aspirin as monotherapy in the management of patients following lower extremity endovascular revascularization. The trial failed to recruit the targeted number of patients, likely due to aspects of the design including the lack of option for dual antiplatelet therapy, and inability to identify suitable patients at study sites...
April 1, 2018: Vascular Medicine
https://www.readbyqxmd.com/read/29629844/aspirin-suppresses-components-of-lymphangiogenesis-and-lymphatic-vessel-remodeling-by-inhibiting-the-nf-%C3%AE%C2%BAb-vcam-1-pathway-in-human-lymphatic-endothelial-cells
#14
Orawin Prangsaengtong, Phatcharida Jantaree, Kriengsak Lirdprapamongkol, Lukana Ngiwsara, Jisnuson Svasti, Keiichi Koizumi
Lymphangiogenesis is the process of new vessel formation from pre-existing lymphatic vessels. The process mainly involves cell adhesion, migration, and tubule formation of lymphatic endothelial cells. Tumor-induced lymphangiogenesis is an important factor contributing to promotion of tumor growth and cancer metastasis via the lymphatic system. Finding the non-toxic agents that can prevent or inhibit lymphangiogenesis may lead to blocking of lymphatic metastasis. Recently, aspirin, a non-steroidal anti-inflammatory drug (NSAID), has been reported to inhibit in vivo lymphangiogenesis in tumor and incision wound models, but the mechanisms of actions of aspirin on anti-lymphangiogenesis have been less explored...
April 1, 2018: Vascular Medicine
https://www.readbyqxmd.com/read/29600739/-popcorn-in-the-heart-thromboemboli-in-transit-during-acute-pulmonary-embolism
#15
Akshyaya Pradhan, Raj Sharma, Pravesh Vishwakarma, Rishi Sethi, Varun Shankar Narain
No abstract text is available yet for this article.
March 1, 2018: Vascular Medicine
https://www.readbyqxmd.com/read/29600738/under-utilization-of-statin-medications-in-patients-with-peripheral-artery-disease-or-cerebrovascular-disease
#16
Ehrin J Armstrong, Stephen W Waldo
No abstract text is available yet for this article.
March 1, 2018: Vascular Medicine
https://www.readbyqxmd.com/read/29600737/statin-prescription-rates-and-their-facility-level-variation-in-patients-with-peripheral-artery-disease-and-ischemic-cerebrovascular-disease-insights-from-the-department-of-veterans-affairs
#17
Cameron L McBride, Julia M Akeroyd, David J Ramsey, Vijay Nambi, Khurram Nasir, Erin D Michos, Ruth L Bush, Hani Jneid, Pamela B Morris, Vera A Bittner, Christie M Ballantyne, Laura A Petersen, Salim S Virani
The 2013 American College of Cardiology/American Heart Association cholesterol guideline recommends moderate to high-intensity statin therapy in patients with peripheral artery disease (PAD) and ischemic cerebrovascular disease (ICVD). We examined frequency and facility-level variation in any statin prescription and in guideline-concordant statin prescriptions in patients with PAD and ICVD receiving primary care in 130 facilities across the Veterans Affairs (VA) health care system between October 2013 and September 2014...
March 1, 2018: Vascular Medicine
https://www.readbyqxmd.com/read/29537350/association-of-obstructive-sleep-apnea-with-microvascular-endothelial-dysfunction-and-subclinical-coronary-artery-disease-in-a-community-based-population
#18
Daniel Shpilsky, Sebhat Erqou, Sanjay R Patel, Kevin E Kip, Oluremi Ajala, Aryan Aiyer, Patrick J Strollo, Steven E Reis, Oladipupo Olafiranye
Studies have reported an association between obstructive sleep apnea (OSA) and cardiovascular disease (CVD) morbidity and mortality. Proposed mechanisms include endothelial dysfunction and atherosclerosis. We aimed to investigate the associations of OSA with endothelial dysfunction and subclinical atherosclerotic coronary artery disease (CAD), and assess the impact of race on these associations. We used data from the Heart Strategies Concentrating on Risk Evaluation (Heart SCORE) study, a community-based prospective cohort with approximately equal representation of black and white participants...
March 1, 2018: Vascular Medicine
https://www.readbyqxmd.com/read/29521183/short-and-long-term-mortality-after-pulmonary-embolism-in-patients-with-and-without-cancer
#19
Ghazi Alotaibi, Cynthia Wu, Ambikaipakan Senthilselvan, Michael Sean McMurtry
Pulmonary embolism (PE) is a major cause of mortality and morbidity. It is known that the risk of death varies by provoking factors; however, it is unknown if the risk of death persists beyond the initial diagnosis among patients with cancer-associated and non-cancer provoked patients. In this study, we aimed to investigate the effect of cancer on overall, short- and long-term mortality in a cohort of consecutive incident PE patients. Using administrative databases, we identified all incident cases of PE between 2004 and 2012 in Alberta, Canada...
March 1, 2018: Vascular Medicine
https://www.readbyqxmd.com/read/29502492/endovascular-iliocaval-reconstruction-for-the-treatment-of-iliocaval-thrombosis-from-imaging-to-intervention
#20
Anthony N Hage, Ravi N Srinivasa, Steven D Abramowitz, Kyle J Cooper, Minhaj S Khaja, Geoff D Barnes, Jeffrey Forris Beecham Chick
Thrombosis of the inferior vena cava and iliac veins, known as iliocaval thrombosis, is a common cause of significant morbidity. Patients with chronic iliocaval obstruction often present with life-limiting occlusive symptoms secondary to recurrent lower extremity deep venous thrombosis, swelling, pain, venous stasis ulcers, or phlegmasia. Endovascular iliocaval reconstruction is a technically successful procedure that results in favorable clinical outcomes and stent patency rates with few complications and is often able to relieve debilitating symptoms in affected patients...
March 1, 2018: Vascular Medicine
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