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Dermatology Online Journal

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https://www.readbyqxmd.com/read/27617952/university-of-california-health-system-school-of-medicine-department-of-dermatology
#1
Uc Davis Department Of Dermatology Faculty Recruitment
No abstract text is available yet for this article.
August 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/27617951/zebrafish-for-modeling-skin-disorders
#2
Abigail Cline, Steven R Feldman
The experimental advantages of zebrafish make this model system highly amenable to the field of dermatology. Zebrafish skin development is similar to humans and its genome is ~70% orthologous to the human genome. Its external developmental process allows for genetic manipulation and analysis of embryogenesis within a short time frame with all important internal organs and skin compartments formed within 6 days. Zebrafish models of cutaneous human diseases offer insight into pathogenesis and a unique platform for testing of potential therapies...
August 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/27617950/uremic-pruritus-treated-successfully-with-the-goeckerman-program
#3
Mio Nakamura, John Koo, Tina Bhutani
Uremic pruritus (UP) is a common condition among patients with chronic kidney disease (CKD) on hemodialysis (HD). We report 19 a case of severe UP recalcitrant to conventional therapy including topical corticosteroids, anti-histamines, and phototherapy, 20 which was treated successfully with the Goeckerman regimen consisting of topical coal tar, topical corticosteroids, and broadband 21 UVB (BB-UVB). Little is known about the pathophysiology of UP, and there is currently no consensus or evidence-based 22 treatments for UP...
August 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/27617949/active-tuberculosis-in-a-psoriasis-patient-treated-with-tumor-necrosis-factor-inhibitors-despite-an-initial-negative-tuberculin-skin-test-and-no-known-risk-factors
#4
Kathleen E Gilbert E Gilbert, Iviesan F Manalo, Jashin J Wu
Tumor necrosis factor (TNF) inhibitors are becoming more common in the treatment of moderate-to-severe chronic plaque psoriasis. These medications have a low incidence of serious adverse events and are generally considered safe; however, they do make patients more susceptible to tuberculosis (TB) infection both through latent reactivation and primary infection. We describe a case of a patient who had an initial negative tuberculin skin test (TST), began TNF inhibitor therapy, and then 11 years later was diagnosed with active TB...
August 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/27617948/top-cited-psoriasis-authors-in-4-high-impact-dermatology-journals-2000-2012
#5
Shivani Reddy, Christina Vu, Young Mike Choi, Jashin J Wu
Psoriasis is a largely researched topic with abundant potential for publication in dermatologic journals. We used the Thomson Reuters' Web of Science citation database using the search term "psoriasis" in the titles of any literature published in 4 high-impact dermatology journals. We compiled a ranking of the top 25 cited first authors and top 25 cited authors overall on the subject of psoriasis between 2000-2012. We hope our analysis highlights the achievements of our colleagues and predecessors.
August 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/27617947/external-ear-nodule-revealing-a-disseminated-kaposi-disease
#6
Hanane Rachadi, Youssef Zemmez, Kaoutar Znati, Nadia Ismaili, Badreddine Hassam
Kaposi disease (KD) is an angiogenetic tumor process, characterized by its various clinical aspects. Its pathogenesis is multifactorial and it was attributed to HHV-8 infection. We report an original case of disseminated KD revealed by solitary lesion of external ear in a patient treated by corticosteroids for bullous pemphigoid.
August 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/27617946/a-case-of-pachydermodactyly-in-a-seventeen-year-old-associated-with-repetitive-minor-trauma
#7
W Abdelrahman, M Y Walsh, A Smyth, D Alderice
A boy presented initially to a Rheumatology clinic with a three year history of asymptomatic swelling of the third to fourth proximal interphalangeal (PIP) joints bilaterally. A presumptive diagnosis of seronegative arthritis was made. Sulfasalazine was commenced without improvement and resulted in mood disturbance. Blood tests including ESR, lupus anticoagulant, rheumatoid factor and CCP antibodies were unremarkable. Hand radiographs were normal. MRI showed oedema within soft tissues around PIP joints. His care was transferred to the Rheumatology unit in our hospital and the rheumatological diagnosis was revised; sulfasalazine was stopped and skin biopsy organised...
August 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/27617945/erythematous-papules-over-the-neck-a-diagnostic-conundrum
#8
Anupam Das, Piyush Kumar
Syringomas are common appendageal neoplasms, manifested as skin-colored papules, most commonly distributed over the periorbital region. We describe a patient with syringoma localized over the neck and upper chest.
August 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/27617944/primary-periungual-leiyomyosarcoma
#9
Hanane Rachadi, Nora Derrabi, Farida Marnissi, Soumaya Chiheb
Primary superficial leiomyosarcoma is a very uncommon malignant tumor which occurs most commonly the lower limbs. We report one case of unusual topography of this tumor. An 81-year-old female patient presented with a 2 year history of a periungual tumor of the left index finger. The histopathological and immunohistochemical examination of a biopsy specimen was compatible with the diagnosis of leiomyosarcoma. There was no evidence of metastatic disease. An amputation of the index was performed.
August 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/27617943/frictional-alopecia-of-the-distal-legs-case-series-and-review
#10
Johnny Zhao, Philip R Cohen
UNLABELLED: BackgroundAcquired alopecia of the lower legs may occur secondary to friction due to socks, footwear, or both on the lower extremities. There is scant literature that reports on this phenomenon.Methods and MaterialsWe describe 5 patients who presented with alopecia of their lower legs induced by socks, footwear, or both. METHODS AND MATERIALS: We reviewed PubMed for the following terms: ankle alopecia, friction alopecia, frictional alopecia, lower extremity alopecia, non-scarring leg alopecia, and sock alopecia...
August 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/27617942/mucin-in-the-dermis-a-case-of-tender-tumors
#11
Gina J Ferris, Gina P Spohn, Alejandro Gru, Jessica Kaffenberger
We present an original case report of a 45-year-old woman with a five-month history of sporadic, tender, nodules present on the right upper abdomen, bilateral dorsal wrists, right upper arm, and left flank. Biopsy revealed a mild perivascular infiltrate, increased dermal mucin, and no significant increase in fibroblasts. Presentation and histology were most consistent with nodular lichen myxedematosus (NLM), a rare primary mucinosis. Only four previous cases are reported in the literature to our knowledge. Management of NLM and other subtypes of lichen myxedematosus is not well described...
August 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/27617941/epithelioid-angiosarcoma-of-the-skin-a-malignant-tumor-mimicking-many-different-neoplasms
#12
Jorge Santos-Juanes1, Blanca Vivanco-Allende, Cristina Galache Galache
Epithelioid angiosarcomas are rare malignant mesenchymal tumors. The main problem of these tumors is the complicate clinical and histological diagnosis. We report a case with an immunohistochemical panel. We propose the use of CD31 in the immunohistochemical panel of an undifferenciated tumor with epithelioid features, because it appears to be the only endothelial marker these tumors constantly express.
August 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/27617940/nilontinib-induced-keratosis-pilaris-atrophicans
#13
Shilpi Khetarpal, Apra Sood, Steven D Billings
Keratosis pilaris (KP) is a disorder of follicular keratinization that is characterized by keratin plugs in the hair follicles with surrounding erythema. A 46-year-old man with chronic myelogenous leukemia (CML) was started on nilotinib, a second generation tyrosine kinase inhibitor (TKI). Two months later the patient noticed red bumps on the skin and patchy hair loss on the arms, chest, shoulders, back, and legs. Cutaneous reactions to nilotinib are the most frequent non-hematologic adverse effects reported...
August 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/27617939/fluoroscopy-induced-radionecrosis
#14
Catherine N Tchanque-Fossuo, Faranak Kamangar, Baran Ho, Shurong Chang, Sara E Dahle, Joshua M Schulman, R Rivkah Isseroff
Complications from radiation exposure during fluoroscopic guidance of cardiac catheterization may occur. With repeated procedures, the risk for cutaneous injuries increases. Herein, we describe a 59-year-old man with extensive coronary artery disease, who had undergone multiple revascularization procedures and developed a non-healing ulcer on his left inferior scapula. The patient's medical history, physical exam findings, and histopathology gave clues to a case of radiation-induced dermatitis and necrosis.
August 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/27617938/treatment-of-rosacea-with-topical-ivermectin-cream-a-series-of-34-cases
#15
Marta Mendieta Eckert, Nerea Landa Gundin
Rosacea is a highly prevalent, chronic inflammatory disease. The use of topical ivermectin cream has recently been described in the treatment of rosacea in three clinical trials. We report our experience in a series of 34 patients treated with topical ivermectin cream. The results are a reflection of the reality of clinical practice and the perception of patients of the treatment. We also evaluate the efficacy in cases of mild rosacea and erythematotelangiectatic rosacea which have not been studied in trials...
August 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/27617936/generalized-eruptive-histiocytosis-associated-with-a-novel-fusion-in-lmna-ntrk1
#16
Sarah S Pinney, Richard R Jahan-Tigh, Susan Chon
Non-Langerhans cell histiocytosis (NLCH) is a histiocyte disorder comprised of dermal dendritic histiocytes with a characteristic staining pattern. Erdheim-Chester disease (ECD) is a subset of NLCH in which patients experience bone pain with corresponding changes on imaging. In addition, these patients show other evidence of systemic involvement, which can also be identified with imaging. This disease can occasionally present with cutaneous findings. We present a case of generalized eruptive histiocytosis (GEH), misdiagnosed as ECD, found to have an NTRK1 gene rearrangement...
August 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/27617935/do-non-melanoma-skin-cancer-survivors-use-tanning-beds-less-often-than-the-general-public
#17
Lauren Wiznia, Feng Dai, Anees B Chagpar
Purpose Indoor tanning is associated with an increased risk of non-melanoma skin cancers (NMSC), yet little is known about indoor tanning habits of individuals with a history of NMSC. Methods We examined self-reported history of NMSC and tanning bed use among non-Hispanic white respondents in the 2010 National Health Interview Survey (NHIS), a cross-sectional population-based survey designed to be representative of the civilian US population. We computed weighted population estimates and standard errors using the Taylor series linearization method...
August 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/27617934/comparing-the-efficacies-of-alginate-foam-hydrocolloid-hydrofiber-and-hydrogel-dressings-in-the-management-of-diabetic-foot-ulcers-and-venous-leg-ulcers-a-systematic-review-and-meta-analysis-examining-how-to-dress-for-success
#18
Michael Saco, Nicole Howe, Rajiv Nathoo, Basil Cherpelis
Diabetic foot ulcers and venous leg ulcers are chronic wounds frequently encountered by dermatologists. Choosing appropriate wound dressings can effectively promote wound healing and potentially reduce morbidity and financial burden experienced by patients. The objective of our systematic review and meta-analysis was to evaluate wound healing efficacies of synthetic active dressings in diabetic foot ulcer and venous leg ulcer management. For data collection, PubMed, Embase, Cochrane Library, CINAHL, and clinicaltrials...
August 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/27617734/agminated-melanocytic-nevus-status-post-dabrafenib-therapy-for-metastatic-melanoma
#19
Alfredo Agulló, Brian Hinds, Raquel Santesteban, Josune Mitxelena Mitxelena, Ignacio Yanguas
Agminated melanocytic nevus is an uncommon type of mole, characterized by a local group of macular or papular pigmented lesions, well demarcated, without a common pigmented background. This pattern has also been associated with Spitz nevi, dysplastic melanocytic nevi, and non-melanocytic lesions.We describe the onset of an acquired agminated melanocytic nevus after dabrafenib treatment. Our case highlights paradoxical MAPK activation in the setting of single-agent BRAF blockade and underscores the importance of characterizing the diverse side effects of selective BRAF inhibitors...
July 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/27617733/allergic-contact-dermatitis-from-cetearyl-alcohol-in-thrombocid%C3%A2-ointment
#20
Miquel Armengot-Carbo1 Armengot-Carbo, Mercedes Rodríguez-Serna, Pilar Taberner-Bonastre, Javier Miquel-Miquel
Thrombocid® ointment (Lacer, Barcelona, Spain) is widely used in Spain and other countries for varicose veins and 22 hematomas. To our knowledge, there are no reported cases of allergic contact dermatitis following its use. Herein we present 23 two cases of allergic contact dermatitis to Thrombocid® ointment, owing to cetearyl alcohol.
July 15, 2016: Dermatology Online Journal
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