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Journal of Pediatric and Adolescent Gynecology

Lisa M Moon, Krista J Childress, Reena Isaac, Oluyemisi Adeyemi-Fowode
BACKGROUND: Medical child abuse is a challenging diagnosis to make, particularly in older children with unusual presenting symptoms. CASE: A 7 year old with complex medical history presented with ano-genital bleeding of unknown origin. Extensive laboratory testing, imaging studies, and diagnostic procedures were negative for any etiology. Forensic testing confirmed the blood in her underwear was a genetic match to the patient. Trial separation from the mother was both diagnostic and therapeutic in this case...
July 7, 2018: Journal of Pediatric and Adolescent Gynecology
Faidah Badru, Saxena Saurabh, Armando Salim Munoz-Abraham, Miguel A Guzman, Samiksha Bansal, Kaveer Chatoorgoon
BACKGROUND: Mature ovarian teratomas are common in children. These well-differentiated tumors are typically confined to the ovary. In rare cases, they can rupture leading to granulomatous peritonitis that mimics carcinomatosis. Ovarian tumors with peritoneal/omental implants suggest malignant pathology with different prognosis. CASE: 15-year-old girl with 5 months of abdominal pain, and weight loss. CT abdomen revealed a large mass filling the abdomen. Slightly elevated LDH and CA-125...
July 7, 2018: Journal of Pediatric and Adolescent Gynecology
Naima Khamsi, Melissa D Mendez, Patricia Rojas-Mendez, Sheralyn Sanchez, Sireesha Reddy
BACKGROUND: Rhabdomyolysis can be the result of vigorous physical activity. Typical signs and symptoms at presentation are muscle pain, weakness, or dark colored urine. There is no scientific literature associating rhabdomyolysis to gynecologic signs and symptoms. CASE: We present a case of a 16 year old female who presented to our pediatric emergency department with complaints of progressive left vulvar swelling. The patient underwent an MRI, which showed polymyositis in the rectus abdominus, external and internal obliques and bilateral vastus lateralis muscles...
July 7, 2018: Journal of Pediatric and Adolescent Gynecology
Soren M Johnson, Grisel Trejo, Keli L Beck, Carrie Worsley, Hope Tranberg, Katie L Plax, Julie M Linton
STUDY OBJECTIVE: To identify community priorities, foster awareness of existing supports, and recognize barriers and opportunities to enhance support services for pregnant and parenting teens (PPT). DESIGN: and Setting: A modified World Café event incorporated parallel, rotating focus groups with semi-structured, case-based discussions of salient issues. The event was organized and took place in Forsyth County, North Carolina. PARTICIPANTS: Seventy-eight local health and social service professionals and fifteen PPT representatives INTERVENTIONS AND MAIN OUTCOME MEASURES: Qualitative coding was used to thematically analyze transcript data...
June 27, 2018: Journal of Pediatric and Adolescent Gynecology
Lauren Kanner, Julie Ce Hakim, Christina Davis Kankanamge, Vrunda Patel, Vivian Yu, Emily Podany, Veronica Gomez-Lobo
STUDY OBJECTIVE: Primary ovarian insufficiency (POI) in adolescents not due to cytotoxic therapy has not been well studied. Causes of POI have been described in adults, but adolescents may represent a unique subset necessitating a targeted approach to diagnosis, work-up and treatment. We sought to better characterize adolescent POI through a descriptive multicenter study. DESIGN: Case series of patients with POI. SETTING: Six tertiary care institutions ParticipantsPatients presenting from 2007-2014 aged 13-21 years diagnosed with non-cytotoxic POI, exclusions gonadotoxic therapy, 46XY gonadal dysgenesis, lack of evidence of hypergonadotropic hypogonadism on chart review...
June 22, 2018: Journal of Pediatric and Adolescent Gynecology
Jacquelyn M Powers, Joseph R Stanek, Lakshmi Srivaths, Fareeda W Haamid, Sarah H O'Brien
STUDY OBJECTIVE: To assess the frequency, severity, and inpatient management of girls admitted with heavy menstrual bleeding and iron deficiency anemia at U.S. children's hospitals, with a focus on hematologic considerations. DESIGN: Retrospective multicenter cohort study from October 2012 through September 2015. SETTING: Children's hospitals submitting data to the Pediatric Health Information System. PARTICIPANTS: Females, age 8 to 18 years, admitted with both heavy menstrual bleeding and anemia as either a primary or secondary diagnosis...
June 22, 2018: Journal of Pediatric and Adolescent Gynecology
Gina S Sucato, Cynthia Holland-Hall
Peer-review of manuscripts submitted for publication in a scholarly journal is a cornerstone of the scientific process. Most scholars receive little or no training on how to conduct this key component of academic citizenship. This article provides guidance on a systematic approach to performing peer-review.
June 21, 2018: Journal of Pediatric and Adolescent Gynecology
Catherine A Hennessey, Vrunda K Patel, Eshetu A Tefera, Veronica Gomez-Lobo, Catherine A Hennessey, Vrunda K Patel, Eshetu A Tefera, Veronica Gomez-Lobo
STUDY OBJECTIVE: Our goal was to describe the period prevalence of VTE and characterize adolescent female patients diagnosed with VTE by describing their age, race, and number of comorbidities. Adolescent females with estrogen exposure were of particular interest since estrogen-containing contraception increases the risk of VTE. DESIGN, SETTING, PARTICIPANTS: We queried the Pediatric Health Information System database for International Classification of Diseases, Ninth/Tenth Revision, Clinical Modification codes to identify females aged twelve to eighteen years old diagnosed with a VTE or PE from April 2006 - March 2016 in the United States...
June 19, 2018: Journal of Pediatric and Adolescent Gynecology
Jessica Y Shim, Jessica M Madrigal, Juan Aparicio, Ashlesha Patel
STUDY OBJECTIVE: To evaluate the prevalence of anemia among female adolescents and young adults seeking abortion care at a county hospital, and to determine its associated factors. DESIGN: A cross-sectional retrospective study. SETTING: John H. Stroger, Jr. Hospital of Cook County, Chicago, IL. PARTICIPANTS: 2,916 young females (ages 11 to 24 years) who underwent first trimester medical or surgical termination in 2016...
June 18, 2018: Journal of Pediatric and Adolescent Gynecology
Cinzia Chiaramonte, Elettra Vestri, Flavia Tripi, Antonino Giulio Giannone, Marcello Cimador, Ferdinando Cataliotti
BACKGROUND: Female vaginoplasty reconstruction, by choice, is usually performed with adjacent tissue. However in some clinical conditions such as high urogenital confluence sinus, cloacal malformation with extreme vaginal hypoplasia, local tissue may not be available. When vaginal replacement is performed in pediatric patients intestinal segments is preferred to non-operative procedures that require continuative dilations. However mucus production, malignant transformation risk and diversion colitis are important side effects...
June 18, 2018: Journal of Pediatric and Adolescent Gynecology
Jessica Shim, Maggie Dwiggins, Veronica Gomez-Lobo
BACKGROUND: Postoperative complications after transverse vaginal septum excision include stricture formation. The purpose of this report is to describe use of intralesional corticosteroid injections for vaginal strictures. CASE: A 32-year-old gravida-0 with history of transverse vaginal septum and recurrent strictures presented for follow-up of chronic pelvic pain. After her fourth septum revision, the patient underwent a total of seven triamcinolone injections at the septum tissue...
June 18, 2018: Journal of Pediatric and Adolescent Gynecology
Jenny K R Francis, Ariel M de Roche, Christine Mauro, Sara E Landers, Jane Chang, Marina Catallozzi, Carmen Radecki Breitkopf, Susan L Rosenthal
STUDY OBJECTIVE: The study describes adolescent and parent retention and changes in willingness to participate (WTP) in research among adolescents, parents, and adolescent-parent dyads. DESIGN AND SETTING: Adolescent-parent dyads were recruited to participate in a longitudinal study to assess research participation attitudes using simultaneous individual interviews of the adolescent and parent with a return visit one year later using the same interview. PARTICIPANTS: Adolescents (14-17 years old) and their parents...
June 12, 2018: Journal of Pediatric and Adolescent Gynecology
Christos Anthoulakis, Eirini Iordanidou, Anastasia Vatopolou
STUDY OBJECTIVE: Intrauterine devices (IUDs) still remain underused in adolescents. Pain during insertion may prevent adolescents to opt for a levonorgestrel (LNG) - releasing IUD. This study aimed to conduct a systematic review, following the PRISMA guidelines, and critically appraise published data with respect to the efficacy of various substances (analgesics or not) in preventing pain during LNG-IUD insertion in nulliparous women as a proxy for adolescents. DESIGN, SETTING, PARTICIPANTS, INTERVENTIONS, AND MAIN OUTCOME MEASURES: A comprehensive computerized systematic literature search of all English language studies between 2006 and 2016 was performed in PubMed, EMBASE, Scopus, Evidence Based Medicine Reviews (Cochrane Database and Cochrane Central Register of Controlled Trials), and Google Scholar...
June 8, 2018: Journal of Pediatric and Adolescent Gynecology
Nicole Todd, Julia E Boucher, Mylène Bassal, Tania Dumont, Nathalie Fleming
BACKGROUND: An 18-month-old female presenting with severe vulvar ulcers and pancytopenia with investigations revealing P.aeruginosa bacteremia. CASE: Previously healthy 18-month-old female presented with 6 days of fevers, vulvar rash and ulcers. Vulvar cultures demonstrated S.aureus and P.aeruginosa. Bloodwork showed pancytopenia and P.aeruginosa bacteremia. She started broad spectrum antibiotics. Bone marrow aspirate revealed a hypocellular marrow with erythroid dysplasia...
June 6, 2018: Journal of Pediatric and Adolescent Gynecology
Makri Angeliki, Boyce M Alison, Constantine A Stratakis, Lodish Maya
BACKGROUND: The long-term morbidity of childhood cancer survivors is an emerging field as more patients are now expected to live through adulthood. CASE: We describe two adolescent patients with permanent premature ovarian failure and failure of endometrium to respond to estrogen after they received a combination of chemotherapy and pelvic radiation for metastatic Ewing sarcoma. Both girls were pre-pubertal at diagnosis of Ewing sarcoma. Puberty was induced with high-dose estrogen and progesterone; however, none of the patients had withdrawal bleeding...
May 29, 2018: Journal of Pediatric and Adolescent Gynecology
Lina Michala, Elpis Vlachopapadopoulou, Pandelis Tsimaris, Georgia Papaioannou, Anna Paisiou, Ioulia Peristeri, Stephanos Michalacos, Vassiliki Kitra
BACKGROUND: Bone Marrow Transplant (BMT) is a lifesaving procedure for a range of serious benign or malignant hematological conditions. A proportion of patients however will develop Graft Versus Host Disease (GVHD), acute or chronic, with serious long term sequalae. CASES: We present two cases of hematocolpos that developed in adolescence because of vaginal synechiae due to GVHD. The condition was initially asymptomatic, resolved spontaneously at first and recurred...
May 29, 2018: Journal of Pediatric and Adolescent Gynecology
K V Greco, L G Jones, I Obiri-Yeboa, T Ansari
STUDY OBJECTIVE: our aim was to use porcine vagina to create a vaginal matrix and test its cellular biocompatibility. DESIGN: vagina was harvested from pigs and de-cellularised (DC) using a combination of detergents (Triton x-100 and sodium deoxycholate) and enzymes (DNAse/RNAse). INTERVENTIONS: the presence of cellular material, collagen structural integrity and basement membrane proteins were assessed histologically. To address cytocompatibility, porcine adipose derived-mesenchymal stem cells (AD-MSC) were harvested from abdominal fat together with vaginal epithelial cells (VEC) and seeded onto the mucosal aspect of the vaginal scaffold...
May 21, 2018: Journal of Pediatric and Adolescent Gynecology
Ayamo G Oben, Oliver Batiste, Kunuwo Fokong, Sasha Davidson, Ometeotl M Acosta
STUDY OBJECTIVE: To identify risk factors for primary non-elective cesarean delivery, in a predominantly Hispanic teen population of an urban tertiary care center DESIGN: Retrospective descriptive study SETTING: A tertiary academic center with ∼3000 deliveries per year PARTICIPANTS: Our study population comprised of all women (ages 13-19 at time of delivery) who gave birth at our tertiary university hospital between July 2011 and July 2016. INTERVENTIONS: None MAIN OUTCOME MEASURE(S): Our main outcome of interest was primary non-elective cesarean delivery RESULTS AND CONCLUSIONS: Of the 958 included deliveries, 9...
May 10, 2018: Journal of Pediatric and Adolescent Gynecology
Golfo Tzilos Wernette, Erin E Bonar, Frederic C Blow, Maureen A Walton
STUDY OBJECTIVE: Pregnant and non-pregnant populations in the US report marijuana as the most commonly used illicit drug. Patterns of marijuana use and psychosocial correlates are unclear among non-treatment seeking teenage girls. DESIGN, SETTING AND PARTICIPANTS: The objective of this study was to use cross-sectional data to examine the psychosocial correlates of recent marijuana use among a sample of 646 pregnant and non-pregnant adolescent girls presenting to urban primary care clinics (mean age = 15...
May 8, 2018: Journal of Pediatric and Adolescent Gynecology
Roman Chmel, Marta Novackova, Zlatko Pastor, Jiri Fronek
STUDY OBJECTIVE: The goal of this study was to assess a group of Mayer-Rokitansky-Küster-Hauser syndrome (MRKH) women with surgically created neovaginas in the interest of uterus transplantation (UTx) and to recruit the first group of applicants for a uterus transplant trial. DESIGN: and Setting: This is an original prospective study using semistructured interviews. PARTICIPANTS: A study group of 50 MRKH syndrome women with Vecchietti neovaginas was recruited by letter of invitation...
May 8, 2018: Journal of Pediatric and Adolescent Gynecology
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