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Spinal Cord

Junsik Kim, Bum Suk Lee, Hye-Jin Lee, Hye-Ri Kim, Duk-Youn Cho, Jung-Eun Lim, Jin-Ju Kim, Ha Yeon Kim, Zee-A Han
STUDY DESIGN: A pilot randomized controlled trial. OBJECTIVES: To evaluate the clinical efficacy of upper limb robotic therapy in people with tetraplegia. SETTING: Inpatient rehabilitation hospital in Seoul, Korea. METHODS: Participants were randomly allocated to a robotic therapy (RT) or occupational therapy (OT) group. Both groups received usual care plus 30 min of additional therapy per day for 4 weeks. The additional therapy provided to the OT group was OT, and the additional therapy provided to RT group was RT using the Armeo Power...
September 11, 2018: Spinal Cord
Mahsa Ghajarzadeh, Hooshang Saberi
STUDY DESIGN: Cross-sectional retrospective study. OBJECTIVE: To describe the transportation mode to hospital and timing of spinal cord decompression and stabilization (D&S), length of hospital stay, frequency of pressure injuries, and sepsis during hospitalization. SETTING: Brain and Spinal Injury Research Center, Tehran, Iran. METHODS: Eight hundred and thirty patients with traumatic spinal cord injury (TSCI) were enrolled...
September 10, 2018: Spinal Cord
Erin E Cunningham, Jeremy W Noble, Andrei Krassioukov, Lara A Boyd, Janice J Eng
STUDY DESIGN: Prospective cross-sectional study OBJECTIVES: The objective of this study was to assess associations between white matter changes and functional motor markers including grip strength and prehension in the upper limb. SETTING: Single Center Imaging Study, in Vancouver Canada. METHODS: Diffusion tensor imaging produced FA (Fractional Anisotropy) maps of the brain for participants with SCI (n = 7) and controls (n = 6). These FA maps were analyzed using tract-based spatial statistics...
September 5, 2018: Spinal Cord
G Stampacchia, A Massone, A Gerini, E Battini, S Mazzoleni
STUDY DESIGN: Multicentric prospective psychometric study. OBJECTIVE: To provide a translation of the International Spinal Cord Injury Pain Basic Data Set (ISCIPBDS) for Italian persons and to evaluate the interrater reliability of the translated version. SETTING: Ten Italian rehabilitation centres specialized in spinal injury care. METHODS: The initial translation was performed by two medical doctors who had an in-depth knowledge of spinal cord injury (SCI), and then a back translation (from Italian to English) was given to an accredited agency...
August 24, 2018: Spinal Cord
Helen Thrussell, Maureen Coggrave, Allison Graham, Angela Gall, Michelle Donald, Richa Kulshrestha, Tracey Geddis
STUDY DESIGN: Cross-sectional phenomenological qualitative study. OBJECTIVES: To investigate women's experience of sexuality after spinal cord injury (SCI) with a focus on rehabilitation and manging practical impact. SETTING: Women with SCI living in the community in United Kingdom (UK). METHODS: Participants were recruited via three UK SCI centres, ensuring tetraplegia, paraplegia and cauda equina syndrome representation...
August 23, 2018: Spinal Cord
Amanda L Botticello, David Tulsky, Allen Heinemann, Susan Charlifue, Claire Kalpakjian, Mary Slavin, Rachel Byrne, Tanya Rohrbach
STUDY DESIGN: Secondary analysis of cross-sectional data from a multisite cohort study. OBJECTIVES: To analyze the association between the built environment and physical functioning reported by adults living with chronic spinal cord injury (SCI). SETTING: Four US Spinal Cord Injury Model Systems centers in New Jersey, Colorado, Illinois, and Michigan. METHODS: Participants were from the Spinal Cord Injury-Functional Index/Capacity (SCI-FI/C) development study...
August 14, 2018: Spinal Cord
Marlene Elmelund, Fin Biering-Sørensen, Mette Hornum Bing, Niels Klarskov
STUDY DESIGN: Observational cross-sectional study. OBJECTIVES: Due to weakened pelvic floor muscles, the risk of pelvic organ prolapse (POP) may increase after a spinal cord injury (SCI); hence, the aim of this study was to investigate the occurrence of POP after SCI and to evaluate the need for urogynecological consultations offered to women with SCI. SETTING: Clinic for Spinal Cord Injuries, Rigshospitalet, Denmark. METHODS: Women with SCI who visited our SCI-clinic during January 2013-January 2018 were offered a specialized urogynecological consultation...
August 10, 2018: Spinal Cord
Michael F La Fountaine, Christopher M Cirnigliaro, Joshua C Hobson, Trevor A Dyson-Hudson, Cristin Mc Kenna, Steven C Kirshblum, Ann M Spungen, William A Bauman
STUDY DESIGN: Retrospective cohort. OBJECTIVE: This report identified the serum triglyceride (TG) concentrations in persons with spinal cord injury (SCI) and able-bodied (AB) individuals that the serum high-density lipoprotein cholesterol (HDL-C) equaled 40 mg/dl, a concentration below which is an independent risk factor for coronary artery disease. METHODS: Retrospective analysis was performed on 578 participants: 223 with SCI at or proximal to the 4th thoracic vertebrae (↑T4), 178 with SCI at or distal to the 5th thoracic vertebrae (↓T5), and 177 AB...
August 8, 2018: Spinal Cord
Nicole D DiPiro, David Murday, Elizabeth H Corley, James S Krause
STUDY DESIGN: Retrospective analysis of self-report and administrative billing data. OBJECTIVES: (1) Identify the self-reported prevalence of seven chronic health conditions (CHCs) in adults with chronic, traumatic spinal cord injury (SCI), (2) Examine the relationships between the presence of CHC with future hospital admissions and total number of inpatient days and (3) identify predictors of utilization. SETTING: Data were collected from participants living in and utilizing hospitals in South Carolina, USA...
August 8, 2018: Spinal Cord
Tao Zhang, Shuangfei Ni, Zixiang Luo, Ye Lang, Jianzhong Hu, Hongbin Lu
STUDY DESIGN: Experimental animal study. OBJECTIVES: To validate the anti-apoptosis effect of microRNA-21 in neurons after spinal cord injury (SCI) and explore the mechanism. SETTING: Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China. METHODS: In situ hybridization was used to detect the expression of miR-21 in spinal cord neurons (n = 24). In a rat contusion SCI model (n = 48), we upregulated the miR-21 level around the injured area using miR-21 lentiviral vectors and evaluated the therapeutic effect with histology and behavioural scores...
August 8, 2018: Spinal Cord
Victor F Leite, Daniel R de Souza, Marta Imamura, Linamara R Battistella
STUDY DESIGN: Retrospective cohort. OBJECTIVE: To evaluate the survival outcomes in patients with traumatic spinal cord injury (TSCI). SETTING: A teaching hospital in Brazil. METHODS: A total of 434 patients diagnosed with TSCI (2004-2014) were included. Overall survival, standardized mortality ratios (SMR), and causes of death were assessed by Student's t-test, χ2 test, Kaplan-Meier analysis, and Cox proportional-hazards regression...
August 8, 2018: Spinal Cord
Vijayanth Kanagaraju, P K Karthik Yelamarthy, Harvinder Singh Chhabra, Ajoy Prasad Shetty, Ankur Nanda, Gururaj M Sangondimath, Kali Dutta Das, Murari Lal Bansal, Bibhudendu Mohapatra, Nishit Patel, Rainer Abel, Sagun Tuli, Tarsissio Barros, Vikas Tandon
STUDY DESIGN: A psychometrics study. OBJECTIVES: To determine intra and inter-observer reliability of Allen Ferguson system (AF) and sub-axial injury classification and severity scale (SLIC), two sub axial cervical spine injury (SACI) classification systems. SETTING: Online multi-national study METHODS: Clinico-radiological data of 34 random patients with traumatic SACI were distributed as power point presentations to 13 spine surgeons of the Spine Trauma Study Group of ISCoS from seven different institutions...
August 8, 2018: Spinal Cord
Nicholas E Koutrakis, Rebekah L Goldstein, Palak Walia, Madeline M Polak, Antonio A Lazzari, Carlos G Tun, Jaime E Hart, Eric Garshick
STUDY DESIGN: Cross-sectional study. OBJECTIVES: Determine dietary, lifestyle, and clinical factors associated with plasma 25-hydroxyvitamin D [25(OH)D] levels in persons with chronic spinal cord injury (SCI). SETTING: Veterans Affairs Medical Center in Boston, MA. METHODS: 174 participants completed food frequency and health questionnaires, provided a blood sample, and underwent dual x-ray absorptiometry (DXA) to assess %total body fat...
August 8, 2018: Spinal Cord
Alessio Conti, Marco Clari, Lorenza Garrino, Patrizia Maitan, Giorgio Scivoletto, Lucia Cavallaro, Barbara Bandini, Silvia Mozzone, Ercole Vellone, Simona Frigerio
DESIGN: Validation cross-sectional study. OBJECTIVES: Even though caregiver burden (CB) represents a well-recognised concern among caregivers of people with a spinal cord injury (SCI), there are no specific questionnaires designed for its evaluation. This study aimed to assess the psychometric properties of the Caregiver Burden Inventory in Spinal Cord Injury (CBI-SCI), which was modified from its original version, and specifically its construct and reliability...
August 1, 2018: Spinal Cord
Sara J T Guilcher, Mary-Ellen Hogan, Andrew Calzavara, Sander L Hitzig, Tejal Patel, Tanya Packer, Aisha K Lofters
STUDY DESIGN: Retrospective cohort study. OBJECTIVES: The objectives for this study were to examine the prevalence of polypharmacy for people with traumatic spinal cord injury (SCI) following injury and to determine risk factors. SETTING: Ontario, Canada METHODS: We used provincial-level administrative health services data of publicly funded healthcare encounters housed at the Institute for Clinical Evaluative Sciences, Toronto, Ontario. We examined prescription medications dispensed over a 1 year period post injury for persons 66+ years with an index traumatic SCI between 2004 and 2014...
July 31, 2018: Spinal Cord
Xiangzhe Li, Qinfeng Wu, Caizhong Xie, Can Wang, Qinghua Wang, Chuanming Dong, Lu Fang, Jie Ding, Tong Wang
STUDY DESIGN: Experimental study. OBJECTIVES: To investigate the role of BDNF-TrkB signaling that promotes the recovery of neurological function in rats with incomplete spinal cord injury (SCI) after treadmill training (TT). SETTING: Rehabilitation Medicine Center of the First Affiliated Hospital of Nanjing Medical University, Nanjing, China. METHODS: Forty rats were divided into five groups: (i) Sham; (ii) SCI and phosphate-buffered saline (PBS) (SCI/PBS); (iii) SCI-TT/PBS; (iv) SCI/TrkB-IgG; and (v) SCI-TT/TrkB-IgG...
July 12, 2018: Spinal Cord
Emelie Butler Forslund, Vivien Jørgensen, Kirsti Skavberg Roaldsen, Claes Hultling, Kerstin Wahman, Erika Franzén
STUDY DESIGN: Prediction study. OBJECTIVES: To investigate the prediction accuracy of the Downton fall risk index (DFRI) and a question of falls the previous year; further to examine the association between time to first fall and risk indicators for falls in wheelchair users and ambulatory persons with Spinal Cord Injury (SCI). SETTING: Two SCI centres in Norway and Sweden (Sunnaas Rehabilitation Hospital, Rehab Station Stockholm /Spinalis)...
July 9, 2018: Spinal Cord
Emil Kostovski, Elena Frigato, Mladen Savikj, Anders Dahm, Per Morten Sandset, Marie-Christine Mowinckel, Grethe Skretting, Bjarne Østerud, Cristiano Bertolucci, Per Ole Iversen
STUDY DESIGN: Crossover double blind, randomized placebo-controlled trial. OBJECTIVES: Circadian oscillators are located both in the brain and in peripheral organs. Melatonin, the main brain-derived hormone governing circadian variations, is highly associated with daylight patterns. However, in subjects with tetraplegia the melatonin levels are blunted. Here we studied peripheral oscillators in peripheral blood mononuclear cells (PBMCs) in males with tetraplegia by examining how exogenous melatonin may influence the expression of clock gene mRNAs...
July 9, 2018: Spinal Cord
Jae-Hyun Yun, Seong-Min Chun, Ju-Chan Kim, Hyung-Ik Shin
STUDY DESIGN: Cross-sectional. OBJECTIVES: To determine the obesity cutoff values for body mass index (BMI) and waist circumference (WC) in Korean men with motor complete spinal cord injury (SCI). SETTING: Tertiary level hospital in Seoul, Korea. METHODS: BMI (kg/m2 ) was calculated and WC (cm) was measured in each participant in the supine position. Percentage of total body fat (%) was determined using whole-body dual-energy X-ray absorptiometry...
July 5, 2018: Spinal Cord
Andréane Richard-Denis, Cynthia Thompson, Jean-Marc Mac-Thiong
STUDY DESIGN: Prospective cohort study. OBJECTIVES: To evaluate the relationship between quality of life (QOL) after a traumatic spinal cord injury (TSCI) and acute predictors, with a particular emphasis on the initial severity of the neurological injury. Secondarily, to compare the QOL after a TSCI with the general population. SETTING: A single Level-1 SCI-trauma centre. METHODS: A cohort of 119 individuals admitted after a cervical TSCI between April 2010 and September 2016 was studied...
July 3, 2018: Spinal Cord
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