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Evidence-based Medicine

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https://www.readbyqxmd.com/read/28720642/evidence-based-medicine-manifesto-for-better-healthcare-a-response-to-systematic-bias-wastage-error-and-fraud-in-research-underpinning-patient-care
#1
EDITORIAL
Carl Heneghan, Kamal R Mahtani, Ben Goldacre, Fiona Godlee, Helen Macdonald, Duncan Jarvies
No abstract text is available yet for this article.
July 18, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28716810/clinicians-should-assess-the-benefits-and-risks-of-using-bezlotoxumab-for-reducing-the-risk-of-recurrent-clostridium-difficile-infection
#2
Habiba Hassouna, Abhishek Deshpande
No abstract text is available yet for this article.
July 17, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28716809/determining-clinical-decision-thresholds-for-hiv-positive-patients-suspected-of-having-tuberculosis
#3
Tom Boyles, Isabella Locatelli, Nicolas Senn, Mark Ebell
Clinical decision thresholds may aid the evaluation of diagnostic tests but have rarely been determined for tuberculosis (TB). We presented clinicians with six web-based clinical scenarios, describing patients with HIV and possible TB at various sites and with a range of clinical stability. The probability of disease was varied randomly and clinicians asked to make treatment decisions; threshold curves and therapeutic thresholds were calculated. Test and treatment thresholds were calculated using Bayes theorem and the diagnostic accuracy of Xpert MTB/RIF...
July 17, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28716808/second-trimester-levothyroxine-treatment-for-subclinical-hypothyroidism-or-hypothyroxinaemia-of-pregnancy-does-not-improve-cognitive-outcomes-of-children
#4
Alex Stagnaro-Green
No abstract text is available yet for this article.
July 17, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28716807/antenatal-corticosteroid-administration-between-24-hours-and-7-days-before-extremely-preterm-delivery-is-associated-with-the-lowest-rate-of-mortality
#5
Colm P Travers, Waldemar A Carlo
No abstract text is available yet for this article.
July 17, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28705922/the-cochrane-collaboration-withdraws-a-review-on-methylphenidate-for-adults-with-attention-deficit-hyperactivity-disorder
#6
Kim Boesen, Luis Carlos Saiz, Juan Erviti, Ole Jakob Storebø, Christian Gluud, Peter C Gøtzsche, Karsten Juhl Jørgensen
A Cochrane systematic review on immediate-release methylphenidate for adults with attention deficit hyperactivity disorder (ADHD) was withdrawn from the Cochrane Library on 26 May 2016 after substantial criticism of its methods and flawed conclusions. Retraction of scientific papers on this basis is unusual but can be necessary. We provide a summary of the criticism that led to the withdrawal. We detail the methodological flaws of the withdrawn Cochrane systematic review and general issues of bias and shortcomings of the included ADHD trials: cross-over designs compared with parallel-group designs, exclusion of participants with psychiatric comorbidity, absence of 'functional outcomes' and use of clinical outcomes with limited relevance, short trial duration and small trial populations, broken blinding caused by easily recognisable side effects, combining outcome assessments by trial investigators and participants, outcome reporting bias, poor evaluation of cardiovascular and psychiatric harms and conflicts of interest of trialists and systematic reviewers...
July 13, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28705921/apixaban-may-have-lower-risk-of-gi-bleeding-compared-with-dabigatran-and-rivaroxaban-in-patients-with-atrial-fibrillation
#7
José Miguel Rivera-Caravaca, Gregory Y H Lip
No abstract text is available yet for this article.
July 13, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28701373/antibiotic-utilisation-in-very-low-birth-weight-infants-without-sepsis-or-necrotising-enterocolitis-is-associated-with-multiple-adverse-outcomes
#8
Jessica L Roberts, Ravi M Patel
No abstract text is available yet for this article.
July 12, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28701372/guidelines-for-reporting-meta-epidemiological-methodology-research
#9
Mohammad Hassan Murad, Zhen Wang
Published research should be reported to evidence users with clarity and transparency that facilitate optimal appraisal and use of evidence and allow replication by other researchers. Guidelines for such reporting are available for several types of studies but not for meta-epidemiological methodology studies. Meta-epidemiological studies adopt a systematic review or meta-analysis approach to examine the impact of certain characteristics of clinical studies on the observed effect and provide empirical evidence for hypothesised associations...
July 12, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28684430/percutaneous-coronary-intervention-has-similar-5-year-survival-rates-to-coronary-artery-bypass-grafting-surgery-for-patients-with-unprotected-left-main-artery-disease
#10
Carlos Collet, Patrick W Serruys
No abstract text is available yet for this article.
July 6, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28663203/use-of-the-m-chat-follow-up-interview-m-chat-f-by-paediatricians-during-well-child-care-visits-is-feasible-valid-and-reliable
#11
Thyde Dumont-Mathieu
No abstract text is available yet for this article.
June 29, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28646127/induction-of-labour-at-37-weeks-for-suspected-fetal-macrosomia-may-reduce-birth-trauma
#12
Kate Walker, Jim Thornton
No abstract text is available yet for this article.
June 23, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28637684/placebo-might-be-superior-to-antipsychotics-in-management-of-delirium-in-the-palliative-care-setting
#13
Soenke Boettger, Josef Jenewein
No abstract text is available yet for this article.
June 21, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28554944/how-good-is-the-evidence-to-support-primary-care-practice
#14
Mark H Ebell, Randi Sokol, Aaron Lee, Christopher Simons, Jessica Early
Our goal was to determine the extent to which recommendations for primary care practice are informed by high-quality research-based evidence, and the extent to which they are based on evidence of improved health outcomes (patient-oriented evidence). As a substrate for study, we used Essential Evidence, an online, evidence-based, medical reference for generalists. Each of the 721 chapters makes overall recommendations for practice that are graded A, B or C using the Strength of Recommendations Taxonomy (SORT)...
May 29, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28546146/criticisms-of-the-vapour-trial-in-a-recent-commentary-are-unsubstantiated-and-incorrect
#15
LETTER
William Clark, Paul Bird, Terry Diamond, Peter Gonski, Elizabeth Barnes, Val Gebski
No abstract text is available yet for this article.
May 25, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28526711/urine-concentration-should-be-taken-into-account-when-interpreting-pyuria-in-infants
#16
Shouja Alam, Judith van der Voort, Christopher C Butler
No abstract text is available yet for this article.
May 19, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28512110/in-patients-with-intracerebral-haemorrhage-and-concomitant-atrial-fibrillation-optimal-timing-of-reinitiating-anticoagulants-may-be-7-8-weeks-after-ich
#17
Catharina Jm Klijn, Floris Hbm Schreuder
No abstract text is available yet for this article.
May 16, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28512109/resumption-of-anticoagulation-after-major-bleeding-decreases-the-risk-of-stroke-in-patients-with-atrial-fibrillation
#18
Marcelle D Smit, Isabelle C Van Gelder
No abstract text is available yet for this article.
May 16, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28501803/among-opioid-naive-patients-receiving-opioids-more-intensive-opioid-prescribing-in-the-first-month-is-associated-with-transition-to-long-term-opioid-use
#19
Marc R Larochelle
No abstract text is available yet for this article.
May 13, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28500063/oral-antibiotics-are-as-effective-as-intravenous-antibiotics-for-postdischarge-treatment-of-complicated-pneumonia-in-children
#20
Igho Onakpoya
No abstract text is available yet for this article.
May 12, 2017: Evidence-based Medicine
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