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Evidence-based Medicine

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https://www.readbyqxmd.com/read/28818966/meta-analysis-using-individual-participant-data-from-randomised-trials-opportunities-and-limitations-created-by-access-to-raw-data
#1
Ewelina Rogozińska, Nadine Marlin, Shakila Thangaratinam, Khalid S Khan, Javier Zamora
Meta-analysis based on individual participant data (IPD), often described as the 'gold standard' for effectiveness evidence synthesis, is increasingly being deployed despite being more resource intensive than collating study-level results. Its professed virtues include the ability to incorporate unreported data and to standardise variables and their definitions across trials. In reality, the unreported data, although present in shared datasets, might still not be usable in the analysis. The characteristics of trial participants and their outcomes may be too diversely captured for harmonisation and too time and resource consuming to standardise...
August 17, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28818965/parent-delivered-cbt-may-reduce-intervention-cost-but-questions-arise-about-effectiveness
#2
Gabriela M Hungerford, Lauren C Santucci, John R Weisz
No abstract text is available yet for this article.
August 17, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28818964/caffeine-does-not-increase-the-arrhythmic-burden-in-patients-with-heart-failure-and-left-ventricular-systolic-dysfunction
#3
Daniel Caldeira
No abstract text is available yet for this article.
August 17, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28818963/uspstf-is-unable-to-recommend-for-or-against-lipid-screening-to-identify-multifactorial-dyslipidaemia-in-childhood-no-recommendation-is-not-without-consequences
#4
REVIEW
Sarah D de Ferranti, Radley C Sheldrick
Paediatric lipid screening has been recommended for decades to identify youth at increased risk for early atherosclerotic disease but is controversial and not universally adopted. A 2016 review by the US Preventive Services Task Force (USPSTF) found inadequate evidence to recommend for or against lipid screening in childhood. In this Perspective article, we examine this controversial and important topic more broadly. We consider whether the USPSTF framework is asking the right questions, and whether the answers to these questions should be valued equally, whether the USPSTF questions are answerable and by what types of evidence and whether the burden of proof is appropriate...
August 17, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28818962/comparing-levels-of-evidence-between-choosing-wisely-and-essential-evidence-plus
#5
LETTER
Joseph R Yancey, Kenneth W Lin
No abstract text is available yet for this article.
August 17, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28814450/in-localised-prostate-cancer-radical-prostatectomy-was-associated-with-more-sexual-dysfunction-and-urinary-incontinence-than-radiation-or-active-surveillance
#6
Zachary L Smith, Scott E Eggener
No abstract text is available yet for this article.
August 16, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28814449/haem-iron-and-nitrate-nitrite-account-for-much-of-the-mortality-increase-associated-with-red-meat-consumption
#7
Sabine Rohrmann, Jakob Linseisen
No abstract text is available yet for this article.
August 16, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28801320/in-stable-copd-long-acting-muscarinic-antagonist-plus-long-acting-beta-agonists-resulted-in-less-exacerbations-pneumonia-and-larger-improvement-in-fev-1-than-long-acting-beta-agonists-plus-inhaled-corticosteroids
#8
https://www.readbyqxmd.com/read/28780494/early-renin-angiotensin-system-inhibition-induced-renal-deterioration-may-be-a-predictor-for-long-term-cardiorenal-outcomes
#9
Redi Llubani, Michael Böhm
No abstract text is available yet for this article.
August 5, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28775170/routine-invasive-strategies-compared-with-conservative-strategies-do-not-lower-the-all-cause-mortality-in-patients-with-non-st-elevation-myocardial-infarction-and-unstable-angina
#10
https://www.readbyqxmd.com/read/28765141/meniscal-resection-may-not-benefit-patients-with-traumatic-meniscal-tears
#11
Raine Sihvonen
No abstract text is available yet for this article.
August 1, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28756394/over-half-of-the-patients-who-undergo-adjustable-gastric-banding-may-require-revision-bariatric-surgery
#12
Christopher de Gara, Vanessa Falk
No abstract text is available yet for this article.
July 29, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28735279/value-of-screening-for-and-treating-pre-diabetes-is-reduced-by-low-test-accuracy-and-indirect-evidence-of-impact-on-patient-important-outcomes
#13
Neri A Alvarez-Villalobos, Rene Rodriguez-Gutierrez, Victor M Montori
No abstract text is available yet for this article.
July 22, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28735278/longer-screening-intervals-are-recommended-following-a-negative-hpv-test-in-primary-cervical-screening
#14
Julian Peto, Clare Gilham
No abstract text is available yet for this article.
July 22, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28735277/join-the-editorial-board
#15
EDITORIAL
Carl Heneghan
No abstract text is available yet for this article.
July 22, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28735276/mental-health-literacy-in-primary-care-canadian-research-and-education-for-the-advancement-of-child-health-canreach
#16
Eden S N McCaffrey, Samuel Chang, Geraldine Farrelly, Abdul Rahman, David Cawthorpe
The effectiveness of a continuing education programme in paediatric psychopharmacology designed for primary healthcare providers was objectively measured based on the assumption that training would lead to measurable changes in referral patterns and established clinical measures of referred patients. Using established, valid and reliable measures of clinical urgency embedded in to a regional healthcare system since 2002, the referrals to child and adolescent psychiatric services of physicians who participated in the training (n=99) were compared pretraining and post-training, and to non-participating/untrained referring physicians (n=7753) making referrals over the same time period...
July 22, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28720642/evidence-based-medicine-manifesto-for-better-healthcare-a-response-to-systematic-bias-wastage-error-and-fraud-in-research-underpinning-patient-care
#17
EDITORIAL
Carl Heneghan, Kamal R Mahtani, Ben Goldacre, Fiona Godlee, Helen Macdonald, Duncan Jarvies
No abstract text is available yet for this article.
July 18, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28716807/antenatal-corticosteroid-administration-between-24-hours-and-7-days-before-extremely-preterm-delivery-is-associated-with-the-lowest-rate-of-mortality
#18
Colm P Travers, Waldemar A Carlo
No abstract text is available yet for this article.
July 17, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28701373/antibiotic-utilisation-in-very-low-birth-weight-infants-without-sepsis-or-necrotising-enterocolitis-is-associated-with-multiple-adverse-outcomes
#19
Jessica L Roberts, Ravi M Patel
No abstract text is available yet for this article.
July 12, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28546146/criticisms-of-the-vapour-trial-in-a-recent-commentary-are-unsubstantiated-and-incorrect
#20
LETTER
William Clark, Paul Bird, Terry Diamond, Peter Gonski, Elizabeth Barnes, Val Gebski
No abstract text is available yet for this article.
May 25, 2017: Evidence-based Medicine
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