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Diabetes & Metabolism

F Barkas, M Elisaf, V Tsimihodimos, H Milionis
BACKGROUND: Type 2 diabetes mellitus (T2DM) is associated with an increased risk of stroke and an unfavourable outcome following stroke. Apart from pioglitazone, glucose-lowering modalities have not been shown to protect against stroke. Nevertheless, there is evidence from experimental studies of potential neuroprotective effects with dipeptidyl peptidase (DPP)-4 inhibitors, especially if treatment starts before stroke. OBJECTIVE: To perform a meta-analysis of available evidence regarding the risk of stroke in individuals taking DPP-4 inhibitors...
December 1, 2016: Diabetes & Metabolism
G Asghari, Z Ghorbani, P Mirmiran, F Azizi
AIM: Nuts are rich in unsaturated fatty acids as well as other bioactive constituents. The present study investigated the association between nut consumption and the incidence of type 2 diabetes mellitus (T2DM) in a Middle Eastern population. METHODS: The study was conducted within the framework of the Tehran Lipid and Glucose Study (TLGS), in which 1984 participants (920 men and 1064 women) free of DM, aged≥20 years, were followed from phase III (2005-2008) to phase V (2011-2014)...
November 16, 2016: Diabetes & Metabolism
K Chabot, M-S Gauthier, P Y Garneau, R Rabasa-Lhoret
AIM: Obesity is associated with the development of metabolic complications such as insulin resistance (IR). The mechanisms leading to IR remain unclear. This study aimed to investigate the relationship between adipose tissue fibrosis and IR in obese patients before and after bariatric surgery. METHODS: Thirty-five obese patients awaiting bariatric surgery (12 with type 2 diabetes) were included in the study. Non-diabetic patients were classified as either insulin-sensitive (n=11) or insulin-resistant (n=12), based on the Matsuda insulin sensitivity index (ISIMatsuda)...
November 11, 2016: Diabetes & Metabolism
G Meng, H Yang, X Bao, Q Zhang, L Liu, H Wu, H Du, Y Xia, H Shi, X Guo, X Liu, C Li, Q Su, Y Gu, L Fang, F Yu, S Sun, X Wang, M Zhou, Q Jia, Q Guo, K Song, G Huang, G Wang, Y Wu, K Niu
AIM: To comprehensively and exhaustively assess the relationship between serum ferritin levels and incidence of prediabetes in a prospective study. METHODS: This prospective cohort study (n=7380) with a mean follow-up of 3.07 years (range: 1-7, 95% CI: 3.03-3.12) was conducted in Tianjin, China. Blood fasting glucose, oral glucose tolerance test, serum ferritin levels and other potentially confounding factors were measured at baseline and at each year of follow-up...
November 11, 2016: Diabetes & Metabolism
Kanza Benomar, Stéphanie Espiard, Claire Vahe, Kristell Le Mapihan, Arnaud Jannin, Sébastien Dharancy, Marc Hazzan, Marie-Christine Vantyghem
No abstract text is available yet for this article.
November 10, 2016: Diabetes & Metabolism
M Kim, S H Jee, M Kim, H J Yoo, M Kang, J Kim, J H Lee
No abstract text is available yet for this article.
November 10, 2016: Diabetes & Metabolism
D Dubois-Laforgue, C Bellanné-Chantelot, P Charles, A Jacquette, E Larger, C Ciangura, C Saint-Martin, C Rastel, B Keren, J Timsit
No abstract text is available yet for this article.
November 9, 2016: Diabetes & Metabolism
L Lei, L Cui, Y Mao, X Zhang, Q Jiang, S Dong, Y Wang
No abstract text is available yet for this article.
November 3, 2016: Diabetes & Metabolism
H Hamasaki, Y Kawashima, H Yanai
No abstract text is available yet for this article.
November 2, 2016: Diabetes & Metabolism
J-Y Kim, J R Choi, I H Park, J H Huh, J-W Son, K W Kim, K-S Park, S-K Cha, J H Sohn, D-H Jung, S-B Koh
No abstract text is available yet for this article.
November 1, 2016: Diabetes & Metabolism
M B Rehman, B V Tudrej, J Soustre, M Buisson, P Archambault, D Pouchain, H Vaillant-Roussel, F Gueyffier, J-L Faillie, M-C Perault-Pochat, C Cornu, R Boussageon
BACKGROUND: Guidelines for type 2 diabetes (T2D) recommend reducing HbA1c through lifestyle interventions and glucose-lowering drugs (metformin, then combination with dipeptidyl peptidase-4 inhibitors [DPP-4Is] among other glucose-lowering drugs). However, no double-blind randomized clinical trial (RCT) compared with placebo has so far demonstrated that DDP-4Is reduce micro- and macrovascular complications in T2D. Moreover, the safety of DPP-4Is (with increased heart failure and acute pancreatitis) remains controversial...
October 10, 2016: Diabetes & Metabolism
G Kim, Y-H Lee, J Y Jeon, H Bang, B-W Lee, E S Kang, I-K Lee, B-S Cha, C S Kim
OBJECTIVE: The association between resting heart rate (RHR) and the development of diabetes has yet to be fully elucidated, and the relationship between changes in RHR and incidence of diabetes also remains unclear. Our study aimed to investigate the association between changes in RHR over 2 years and the risk of diabetes. METHODS: A total of 7416 adults without diabetes were included. All had participated in the Korean Genome and Epidemiology Study, a community-based, 10-year prospective study in which RHR was measured at baseline and 2 years later...
October 10, 2016: Diabetes & Metabolism
A J Cox, P Zhang, D W Bowden, B Devereaux, P M Davoren, A W Cripps, N P West
AIM: Relationships between the intestinal microbiota, intestinal permeability and inflammation in the context of risk for obesity-associated disease continue to be of interest. The aim of the study was to examine the associations between intestinal permeability and type 2 diabetes (T2D). METHODS: A total of 130 individuals with T2D (age: 57.5±6.2 years (mean±SD); BMI: 30.4±3.2; 45% female) and 161 individuals without T2D (age: 37.4±12.5 years; BMI: 25.1±3.9; 65% female) were included in the study...
October 10, 2016: Diabetes & Metabolism
C Dunyach-Remy, C Courtais-Coulon, C DeMattei, N Jourdan, S Schuldiner, A Sultan, C Carrière, S Alonso, A Sotto, J-P Lavigne
AIMS: Nasal carriage of Staphylococcus aureus in diabetic patients may be a risk factor for diabetic foot lesion infections. The aims of this study were to compare the genotypic profiles of S. aureus strains isolated from nares and diabetic foot ulcers (DFUs) using microarray technology. METHODS: Patients were included if they were admitted for diabetic foot infection (DFI) at any of three diabetology departments of Montpellier and Nîmes University Hospitals between 1 September 2010 to 30 June 2012...
October 5, 2016: Diabetes & Metabolism
K Fujihara, R Igarashi, M Yamamoto, M Ishizawa, Y Matsubayasi, S Matsunaga, K Kato, C Ito, M Koishi, N Yamanaka, S Kodama, H Sone
AIMS: To examine the impact of glucose tolerance status on the development of coronary artery disease (CAD) in working-age men in Japan. METHODS: This population-based retrospective cohort study included 111,621 men aged 31-60 years [63,558 with normal glucose tolerance (NGT); 37,126 with prediabetes; 10,937 with diabetes]. The Cox proportional-hazards regression model was used to identify variables related to the incidence of CAD. RESULTS: Multivariate analysis showed that, compared with NGT, diabetes increased the risk of CAD by 17...
October 3, 2016: Diabetes & Metabolism
M Buysschaert, C Tshongo Muhindo, O Alexopoulou, D Rahelic, H Reychler, V Preumont
No abstract text is available yet for this article.
September 28, 2016: Diabetes & Metabolism
C Vatier, L Arnaud, X Prieur, B Guyomarch, C Le May, E Bigot, M Pichelin, A Daguenel, M-C Vantyghem, J-F Gautier, C Vigouroux, B Cariou
No abstract text is available yet for this article.
September 27, 2016: Diabetes & Metabolism
T Osaka, Y Hashimoto, T Fukuda, M Tanaka, M Yamazaki, M Fukui
No abstract text is available yet for this article.
September 22, 2016: Diabetes & Metabolism
A Moutairou, R Roussel, B Charbonnel, R El Boustany, A Nicolas, A Leye, K Mohammedi, M Marre, B Detournay, L Potier
No abstract text is available yet for this article.
September 21, 2016: Diabetes & Metabolism
J-P Riveline, P Boudou, B Blondeau, J-F Gautier
No abstract text is available yet for this article.
September 21, 2016: Diabetes & Metabolism
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