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Diabetes & Metabolism

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https://www.readbyqxmd.com/read/29146035/renal-outcomes-with-dipeptidyl-peptidase-4-inhibitors
#1
REVIEW
A J Scheen, P Delanaye
Dipeptidyl peptidase-4 inhibitors (DPP-4is) are increasingly being used in the management of type 2 diabetes (T2D). The present review summarizes the current knowledge of the effects of DPP-4is on renal outcomes by analyzing the experimental preclinical data, the effects of DPP-4is on urinary albumin-creatinine ratios (UACRs) and estimated glomerular filtration rates (eGFRs) from observational studies and clinical trials, and renal events (including kidney failure requiring renal replacement therapy) in recent large prospective cardiovascular outcome trials...
November 13, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29129541/weight-gain-in-early-pregnancy-and-risk-of-gestational-diabetes-mellitus-among-latinas
#2
T A Moore Simas, M E Waring, K Callaghan, K Leung, M Ward Harvey, A Buabbud, L Chasan-Taber
AIM: To evaluate the association between gestational weight gain (GWG) in early pregnancy and incidence of abnormal glucose tolerance (AGT) and gestational diabetes mellitus (GDM) among Latinas. METHODS: We conducted a retrospective cohort study of 2039 Latinas using pooled data from two medical centres in Massachusetts. Gestational weights were abstracted from medical records and GWG was categorized as low, appropriate and excessive according to 2009 Institute of Medicine Guidelines...
November 9, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29129540/inhibitory-role-of-oxytocin-on-tnf%C3%AE-expression-assessed-in-vitro-and-in-vivo
#3
S Garrido-Urbani, N Deblon, A L Poher, A Caillon, P Ropraz, F Rohner-Jeanrenaud, J Altirriba
AIM: Oxytocin administration to diet-induced obese (DIO) rodents, monkeys and humans decreases body weight and fat mass with concomitant improvements in glucose metabolism. Moreover, several studies show an immunomodulatory role of oxytocin in a number of settings (such as atherosclerosis, injury, sepsis). This study aims to shed some light on the effects of oxytocin on macrophage polarization and cytokine production, as well as its possible impact on these parameters in adipose tissue in DIO mice with impaired glucose metabolism...
November 9, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29128289/predictors-of-the-response-of-hba1c-and-body-weight-after-sglt2-inhibition
#4
LETTER
T Abe, Y Matsubayashi, A Yoshida, H Suganami, T Nojima, T Osawa, M Ishizawa, M Yamamoto, K Fujihara, S Tanaka, K Kaku, H Sone
No abstract text is available yet for this article.
November 8, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29128288/hypoglycaemic-episodes-and-risk-of-diabetic-peripheral-neuropathy-in-patients-with-type-2-diabetes
#5
LETTER
Y-W Pai, C-H Lin, I-T Lee, M-H Chang
No abstract text is available yet for this article.
November 8, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29126785/glycated-heamoglobin-a1c-as-a-tool-for-epidemiological-studies-to-assess-diabetes-prevalence-how-has-it-been-used-since-its-official-recommendation-for-diabetes-diagnosis
#6
EDITORIAL
https://www.readbyqxmd.com/read/29097005/insulin-secretion-in-response-to-high-extracellular-calcium-is-not-a-pathognomonic-feature-of-insulinoma-cells
#7
LETTER
J-C Henquin, F Pattou, M Nenquin
No abstract text is available yet for this article.
October 30, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29097004/temporal-characterization-of-cardiac-expression-of-glucose-transporters-sglt-and-glut-in-an-experimental-model-of-myocardial-infarction
#8
LETTER
J Sánchez-Más, E Saura-Guillén, M C Asensio-López, Á Soriano-Filiu, M Carmen Sánchez-Pérez, A M Hernandez-Martinez, A Lax, D Pascual-Figal
No abstract text is available yet for this article.
October 30, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29097003/skin-autofluorescence-improves-the-finnish-diabetes-risk-score-in-the-detection-of-diabetes-in-a-large-population-based-cohort-the-lifelines-cohort-study
#9
B T Fokkens, R P van Waateringe, D J Mulder, B H R Wolffenbuttel, A J Smit
AIM: The aim of the present study was to investigate whether skin autofluorescence would improve the Finnish Diabetes Risk Score (FINDRISC) in detecting undiagnosed diabetes in a large population-based cohort. METHODS: Included were participants from the Dutch LifeLines Cohort Study. Skin autofluorescence was assessed in an unselected subset of participants using the AGE Reader. After the exclusion of participants with previously diagnosed diabetes (n=1635), pregnant women (n=58) and those using corticosteroids (n=345), 79,248 subjects were eligible for analysis...
October 30, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29097002/evacuation-is-a-risk-factor-for-diabetes-development-among-evacuees-of-the-great-east-japan-earthquake-a-4-year-follow-up-of-the-fukushima-health-management-survey
#10
LETTER
H Satoh, T Ohira, M Nagai, M Hosoya, A Sakai, S Yasumura, A Ohtsuru, Y Kawasaki, H Suzuki, A Takahashi, Y Sugiura, H Shishido, Y Hayashi, H Takahashi, G Kobashi, K Ozasa, S Hashimoto, H Ohto, M Abe, K Kamiya
No abstract text is available yet for this article.
October 30, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29107455/type-2-diabetes-mellitus-and-risk-of-open-angle-glaucoma-development-in-koreans-an-11-year-nationwide-propensity-score-matched-study
#11
Y Jung, K Han, H-Y L Park, C K Park
PURPOSE: To evaluate the risk of primary open-angle glaucoma (POAG) development in type 2 diabetes mellitus (T2DM) patients. METHODS: In this 11-year longitudinal study based on the Korean National Health Insurance research database, the data collected comprised 1,025,340 (2.2%) participants who were randomly selected from 46,605,433 Korean residents in 2002. The database was analyzed to identify participants with an initial diagnosis of T2DM in 2003-2004. The control group was composed of participants without T2DM who were propensity-score-matched, five controls per T2DM patient, according to age, gender, household income, residential area and underlying diseases, including hypertension, dyslipidaemia, coronary heart disease, cerebrovascular disease and thyroid disease...
October 26, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29074329/degree-of-ketonaemia-and-its-association-with-insulin-resistance-after-dapagliflozin-treatment-in-type-2-diabetes
#12
S H Min, T J Oh, S-I Baek, D-H Lee, K M Kim, J H Moon, S H Choi, K S Park, H C Jang, S Lim
BACKGROUND: Euglycaemic ketoacidosis has been reported after sodium-glucose cotransporter 2 (SGLT2) inhibitor treatment. However, the degree of ketonaemia and its metabolic effects have not been well investigated. Our study examined the degree of ketonaemia induced by SGLT2 inhibition and its association with metabolic profiles in type 2 diabetes mellitus (T2DM). METHODS: Biochemical parameters, including insulin, glucagon, free fatty acid (FFA), β-hydroxybutyrate (BHB) and acetoacetate (ACA) levels, were measured in 119 T2DM patients after dapagliflozin treatment for>3 months, and compared with a matched control group...
October 23, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29074328/fasting-blood-glucose-and-risk-of-prostate-cancer-a-systematic-review-and-meta-analysis-of-dose-response
#13
REVIEW
A Jayedi, K Djafarian, F Rezagholizadeh, A Mirzababaei, M Hajimohammadi, S Shab-Bidar
AIM: This study aimed to test the dose-response relationship between fasting blood glucose (FBG) levels and risk of prostate cancer. METHODS: A systematic search was done of PubMed and Scopus from their inception up to January 2017. Prospective and retrospective studies reporting risk estimates of prostate cancer for two or more categories of blood glucose levels were identified, and two independent authors extracted the information. Relative risk (RR) was calculated using random-effects models and pooled...
October 23, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29066209/changes-in-glucose-lowering-drug-use-before-and-after-cancer-diagnosis-in-patients-with-diabetes
#14
M M J Zanders, H R Haak, M P P van Herk-Sukel, R M C Herings, L V van de Poll-Franse, J A Johnson
AIM: This study explores the changes in glucose-lowering drug (GLD) use before and after cancer diagnosis among patients with diabetes. METHODS: New GLD users (1998-2011) living in the Dutch ECR-PHARMO catchment area were selected from the PHARMO Database Network (n=52,228). Those with a primary cancer diagnosis were considered cases (n=3281) and matched with eligible controls (n=12,891) without cancer during follow-up. Conditional logistic regression analysis was used to assess changes in GLD use, such as treatment add-ons, treatments drops and initiation of insulin, for cases compared with controls associated with specific cancer types in four time windows (6-3 and 0-3months before cancer diagnosis; 0-3 and 3-6months after cancer diagnosis)...
October 21, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29066156/gestational-diabetes-mellitus-screening-according-to-carpenter-coustan-and-iadpsg-criteria-a-7-year-follow-up-of-prevalence-treatment-and-neonatal-complications-at-a-belgian-general-hospital
#15
LETTER
P Oriot, J Radikov, U Gilleman, R Loumaye, V Ryckoort, E Debue, C Neve, A Gruber, S Vermeulen, M Jacob, G Herman, M Buysschaert
No abstract text is available yet for this article.
October 21, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29029946/hypoglycaemia-causes-both-daytime-and-nighttime-qtc-interval-prolongation-in-patients-with-type-2-diabetes-receiving-insulin-treatment
#16
LETTER
K Makrilakis, C Stathi, I Vlahodimitris, S Kalopita, P Thomakos, P Konstantopoulos, D Perrea, N Katsilambros, S Liatis
No abstract text is available yet for this article.
October 10, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29029945/continuous-positive-airway-pressure-improves-sleep-quality-but-not-glycaemic-control-in-patients-with-poorly-controlled-long-standing-type-2-diabetes
#17
LETTER
M Torrella, I Castells, G Gimenez-Perez, A Recasens, M Miquel, O Simó, E Barbeta, G Sampol
No abstract text is available yet for this article.
October 10, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29032950/trajectories-of-fasting-plasma-glucose-variability-and-mortality-in-type-2-diabetes
#18
Chia-Lin Lee, Wayne Huey-Herng Sheu, I-Te Lee, Shih-Yi Lin, Wen-Miin Liang, Jun-Sing Wang, Yu-Fen Li
AIM: To investigate the effect of changes in fasting plasma glucose (FPG) variability, as assessed by 2-year trajectories of FPG variability, on mortality risk in patients with type 2 diabetes (T2D). METHODS: From 2009 to 2012, outpatients with T2D, aged>18 years, were enrolled from a medical centre. FPG was measured every 3 months for 2 years in 3569 people. For each of the eight 3-month intervals, FPG variability and means were calculated, with variability defined as the coefficient of variation of FPG...
October 9, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/28988697/diagnosis-and-management-of-patients-with-significantly-abnormal-glycaemic-profiles-during-pregnancy-after-bariatric-surgery-presage-pregnancy-with-significantly-abnormal-glycaemic-exposure%C3%A2-%C3%A2-bariatric-patients
#19
LETTER
https://www.readbyqxmd.com/read/28986133/glycated-albumin-predicts-the-development-of-early-diabetic-nephropathy-in-patients-with-type-2-diabetes
#20
LETTER
J E Jun, K Y Hur, Y-B Lee, S-E Lee, S-M Jin, M-K Lee, J H Kim
No abstract text is available yet for this article.
October 3, 2017: Diabetes & Metabolism
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