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Diabetes & Metabolism

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https://www.readbyqxmd.com/read/29331269/clinical-benefits-of-autologous-haematopoietic-stem-cell-transplantation-in-type-1-diabetes-patients
#1
B Gu, H Miao, J Zhang, J Hu, W Zhou, W Gu, W Wang, G Ning
Type 1 diabetes (T1D) is characterized by severe damage to pancreas islet function through immunological attack; therefore, it is also called 'insulin-dependent diabetes'. The present study aimed to evaluate the safety and clinical efficacy of autologous haematopoietic stem cell transplantation (AHSCT) in adolescent patients with newly diagnosed T1D. A phase-II prospective, parallel-assignment, non-randomized trial was conducted from March 2008 to December 2011 with 40 T1D patients, of whom 20 received AHSCT therapy and 20 were treated only with insulin injections...
December 22, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29305111/patients-with-diabetes-and-foot-ulcer-present-cognitive-dysfunction-and-express-fewer-needs-in-terms-of-educational-support
#2
LETTER
C Bouché, A Zucchello, P Troude, T Sarron, J Dumurgier, J F Gautier
No abstract text is available yet for this article.
December 19, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29336986/a-systematic-literature-review-of-observational-studies-of-the-bidirectional-association-between-metabolic-syndrome-and-migraine
#3
REVIEW
V A Andreeva, P Galan, C Julia, L Fezeu, S Hercberg, E Kesse-Guyot
AIMS: To evaluate all epidemiological evidence in the literature linking the metabolic syndrome (MetS) and migraine in adults. METHODS: Database (Medline, Embase; published reports up to November 2017) and manual searches were performed. Information on data collection, sample characteristics, study design, MetS and migraine assessment, and results was extracted from each relevant publication. The methodological quality of each study was also assessed. RESULTS: A total of 15 observational epidemiological studies in adults, published between 2009 and 2017, were retrieved...
December 13, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29277378/assessment-of-hypoglycaemia-during-basal-insulin-therapy-temporal-distribution-and-risk-of-events-using-a-predefined-or-an-expanded-definition-of-nocturnal-events
#4
M C Riddle, G B Bolli, A Avogaro, M G Álvarez, A Merino-Trigo, E Boëlle-Le Corfec, P D Home
AIM: To describe in type 2 diabetes the 24-hour distribution of hypoglycaemia and compare the frequency of nocturnal events based on a predefined nocturnal window or an expanded interval, using illustrative data for two insulin glargine formulations. METHODS: Temporal distribution of hypoglycaemic events was assessed descriptively and by profile using participant-level data from three randomized trials comparing insulin glargine 300 U/mL (Gla-300) and 100 U/mL (Gla-100)...
December 11, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29275947/glp-1-agonist-associated-acute-kidney-injury-a-case-report-and-review
#5
LETTER
T Sharma, R Paixao, C Villabona
No abstract text is available yet for this article.
December 9, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29254879/diabetes-related-distress-is-reduced-in-people-with-type-1-but-not-type-2-diabetes-after-participating-in-a-diabetes-treatment-and-teaching-programme
#6
LETTER
N Kuniss, U A Müller, C Kloos, V Jörgens, G Kramer
No abstract text is available yet for this article.
December 5, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29249613/metabolically-healthy-and-unhealthy-weight-statuses-health-issues-and-related-costs-findings-from-the-2013-2015-european-health-examination-survey-in-luxembourg
#7
H Samouda, M Ruiz-Castell, M Karimi, V Bocquet, A Kuemmerle, A Chioti, F Dadoun, S Stranges
AIM: To investigate the relationship between metabolically healthy and unhealthy weight statuses and a wide range of related health issues, and healthcare and loss-of-productivity costs. METHODS: A total of 693 men and 729 women, aged 25-64 years, took part in the European Health Examination Survey conducted in Luxembourg between 2013 and 2015. Metabolically unhealthy normal-weight profiles were defined as having two or more cardiometabolic abnormalities (high blood pressure, high fasting glucose or triglycerides, low HDL cholesterol and/or previously diagnosed hypertension or diabetes) in people with normal weight...
December 1, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29249611/actinic-keratosis-and-diabetes-complications-a-nationwide-population-based-study-in-south-korea-2009-2015
#8
Y Bok Lee, J Hyun Lee, J Young Choi, D Soo Yu, K Do Han, Y Gyu Park
AIM: As the associations between actinic keratosis (AK) and diabetes complications in patients with diabetes mellitus (DM) have never been investigated, this study aimed to evaluate any such associations in patients with DM. METHODS: This retrospective cohort study analyzed clinical data for DM patients aged>40 years who had undergone the health examination recommended by the South Korea National Health Insurance Program between 2009 and 2012 (n=2,056,580). All of these patients were classified according to the presence of diabetic retinopathy (DR), end-stage renal disease (ESRD) and history of DVD; myocardial infarction, stroke, transient ischaemic attacks...
November 29, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29248337/clinical-efficacy-of-the-novel-thiazolidinedione-lobeglitazone-in-patients-with-type-2-diabetes
#9
LETTER
J-Y Lee, Y Cho, M Lee, Y-H Lee, B-W Lee, E S Kang, B-S Cha
No abstract text is available yet for this article.
November 25, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29233451/hyperglycaemic-hyperosmolar-syndrome-in-a-5-year-old-girl-with-newly-diagnosed-type-2-diabetes-mellitus
#10
LETTER
N Al Hassani, W Kaplan
No abstract text is available yet for this article.
November 25, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29249612/does-periodontitis-affect-diabetes-incidence-and-haemoglobin-a1c-change-an-11-year-follow-up-study
#11
T G Kebede, C Pink, W Rathmann, B Kowall, H Völzke, A Petersmann, P Meisel, T Dietrich, T Kocher, B Holtfreter
AIM: As periodontitis may contribute to the pathogenesis of diabetes, the effects of periodontitis on diabetes incidence and HbA1c change was quantified in a prospective cohort. METHODS: Data from an 11-year follow-up of the Study of Health in Pomerania were analyzed to evaluate the effects of periodontitis on incident diabetes and long-term HbA1c changes in 2047 subjects aged 20-81years. Diabetes was based on self-reported physician diagnoses, antidiabetic medication use, or HbA1c≥6...
November 22, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29153486/glucose-variability-do-we-have-to-revisit-the-profusion-of-definitions-to-avoid-confusion
#12
EDITORIAL
L Monnier, C Colette, D Owens
No abstract text is available yet for this article.
November 16, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29153485/morning-administration-of-0-4u-kg-day-insulin-glargine-300u-ml-provides-less-fluctuating-24-hour-pharmacodynamics-and-more-even-pharmacokinetic-profiles-compared-with-insulin-degludec-100u-ml-in-type-1-diabetes
#13
T S Bailey, J Pettus, R Roussel, W Schmider, M Maroccia, N Nassr, O Klein, G B Bolli, R Dahmen
AIM: To compare steady state pharmacodynamic and pharmacokinetic profiles of insulin glargine 300U/mL (Gla-300) with insulin degludec 100U/mL (Deg-100) in people with type 1 diabetes. METHODS: This single-centre, randomized, double-blind crossover euglycaemic clamp study included two parallel cohorts with fixed once-daily morning dose regimens. For both insulins participants received 0.4 (n=24) or 0.6U/kg/day (n=24), before breakfast, for 8 days prior to the clamp...
November 16, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29257747/low-dose-aspirin-for-primary-prevention-of-cardiovascular-events-in-patients-with-diabetes-benefit-or-risk
#14
REVIEW
M Leggio, M G Bendini, E Caldarone, M Lombardi, P Severi, S D'Emidio, D C Stavri, M Armeni, V Bravi, A Mazza
Primary prevention aims to avert the onset of cardiovascular disease (CVD) by targeting its natural causes and risk factors; secondary prevention includes strategies and therapies that address preclinical or clinical evidence of CVD progression. The value of aspirin for primary CVD prevention is controversial because of increased bleeding, which may offset the overall modest benefits in patients with no overt CVD. In contrast, the benefits of aspirin for secondary prevention have been repeatedly and convincingly demonstrated to outweigh the risk of bleeding...
November 14, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29196025/pharmacological-variability-of-insulins-degludec-and-glargine-300u-ml-equivalent-or-not
#15
EDITORIAL
L Monnier, C Colette
No abstract text is available yet for this article.
November 14, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29146035/renal-outcomes-with-dipeptidyl-peptidase-4-inhibitors
#16
REVIEW
A J Scheen, P Delanaye
Dipeptidyl peptidase-4 inhibitors (DPP-4is) are increasingly being used in the management of type 2 diabetes (T2D). The present review summarizes the current knowledge of the effects of DPP-4is on renal outcomes by analyzing the experimental preclinical data, the effects of DPP-4is on urinary albumin-creatinine ratios (UACRs) and estimated glomerular filtration rates (eGFRs) from observational studies and clinical trials, and renal events (including kidney failure requiring renal replacement therapy) in recent large prospective cardiovascular outcome trials...
November 13, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29217386/early-worsening-of-diabetic-retinopathy-after-rapid-improvement-of-blood-glucose-control-in-patients-with-diabetes
#17
REVIEW
S Feldman-Billard, É Larger, P Massin
AIM: To review the frequency, importance of and risk factors for "early worsening of diabetic retinopathy" (EWDR) after rapid improvement of blood glucose in patients with diabetes. METHODS: This was a systematic review of key references (PubMed 1980-2016) and the current international recommendations for the above-mentioned topics. RESULTS: EWDR has been described during intensive treatment (IT) in patients with uncontrolled type 1 or 2 diabetes, and after pancreas transplantation or bariatric surgery...
November 11, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29174479/practical-implementation-education-and-interpretation-guidelines-for-continuous-glucose-monitoring-a-french-position-statement
#18
S Borot, P Y Benhamou, C Atlan, E Bismuth, E Bonnemaison, B Catargi, G Charpentier, A Farret, N Filhol, S Franc, D Gouet, B Guerci, I Guilhem, C Guillot, N Jeandidier, M Joubert, V Melki, E Merlen, A Penfornis, S Picard, E Renard, Y Reznik, J P Riveline, S Rudoni, P Schaepelynck, A Sola-Gazagnes, N Tubiana-Rufi, O Verier-Mine, H Hanaire
The use by diabetes patients of real-time continuous interstitial glucose monitoring (CGM) or the FreeStyle Libre® (FSL) flash glucose monitoring (FGM) system is becoming widespread and has changed diabetic practice. The working group bringing together a number of French experts has proposed the present practical consensus. Training of professionals and patient education are crucial for the success of CGM. Also, institutional recommendations must pay particular attention to the indications for and reimbursement of CGM devices in populations at risk of hypoglycaemia...
November 11, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29169927/metabolic-syndrome-and-impaired-glucose-metabolism-during-early-postpartum-after-twin-pregnancies-complicated-by-gestational-diabetes-mellitus-is-the-risk-comparable-to-singleton-pregnancies
#19
LETTER
M A Guillén-Sacoto, B Barquiel, N Hillman, M A Burgos, L Herranz
No abstract text is available yet for this article.
November 11, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29153750/family-history-of-diabetes-is-associated-with-enhanced-adipose-lipolysis-evidence-for-the-implication-of-epigenetic-factors
#20
I Dahlman, M Ryden, P Arner
AIMS: Type 2 diabetes is associated with insulin resistance, adipose hypertrophy and increased lipolysis. The heritability of these traits has been determined by associating them with a family history of diabetes. METHODS: Abdominal subcutaneous fat biopsies were obtained from 581 subjects in a cross-sectional study. Fat cells were isolated, and the difference between measured and expected fat-cell volume was used to determine adipose morphology (degree of hypertrophy or hyperplasia)...
November 11, 2017: Diabetes & Metabolism
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