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Gefässchirurgie: Zeitschrift Für Vaskuläre und Endovaskuläre Chirurgie

journal
https://www.readbyqxmd.com/read/29527101/-stem-cell-based-strategies-in-vascular-surgery
#1
M Gasser, M H Frank, A M Waaga-Gasser
Critical chronic ischemia in patients with underlying arterial occlusive disease requires vascular reconstructive surgery. The limited supply of suitable small-diameter autologous vascular grafts in many patients and obvious disadvantages of synthetic bypass material demand the development of clinically usable tissue-engineered blood vessel substitutes. Despite substantial progress in the field over the last two decades, their implementation into the clinical routine has been challenging. The limited replicative life span of human adult vascular cells and their slow rate of collagenous matrix production in vitro have posed important problems in the development of mechanically robust and biologically functional engineered grafts...
February 2018: Gefässchirurgie: Zeitschrift Für Vaskuläre und Endovaskuläre Chirurgie
https://www.readbyqxmd.com/read/30412208/erratum-to-complex-endovascular-treatment-of-intact-aortic-aneurysms-an-analysis-of-health-insurance-claims-data
#2
C-A Behrendt, H C Rieß, T Schwaneberg, F Heidemann, N Tsilimparis, A-A Larena-Avellaneda, H Diener, T Kölbel, E S Debus
[This corrects the article DOI: 10.1007/s00772-018-0387-7.].
2018: Gefässchirurgie: Zeitschrift Für Vaskuläre und Endovaskuläre Chirurgie
https://www.readbyqxmd.com/read/30237669/why-i-use-both-prospective-randomized-trials-and-registry-data-when-choosing-the-personalized-treatment-of-an-aaa-patient
#3
REVIEW
M D Shah, S Edeiken, R C Darling Iii
Randomized controlled trials (RCTs) have been the core of level 1 data in medical and surgical science for at least the last three decades. However, frequently patient selection is very narrow, anatomic criteria do not match real-world experience, and much of the work is done in selected academic centers. We use RCTs to help explain the rational for intervention and then rely on longitudinal registries and single center data to give the patients a real-world expectation concerning outcomes and complications in our hands...
2018: Gefässchirurgie: Zeitschrift Für Vaskuläre und Endovaskuläre Chirurgie
https://www.readbyqxmd.com/read/30237668/treatment-of-aortic-aneurysms-registered-in-swedvasc-development-reflected-in-a-national-vascular-registry-with-an-almost-100-coverage
#4
REVIEW
D Bergqvist, K Mani, T Troëng, A Wanhainen
Swedvasc is a registry for vascular surgical procedures, both open and endovascular. It was started in 1987 and since 1994 the whole population of Sweden is covered, at present around 10 million inhabitants. In a recent external validation, it was found to be highly accurate with abdominal aortic aneurysm surgery correctly reported in >96%. In this paper various factors explaining the almost 100% coverage are discussed, one important being that the registry has been developed and maintained within the profession of vascular surgery and not dictated by authorities...
2018: Gefässchirurgie: Zeitschrift Für Vaskuläre und Endovaskuläre Chirurgie
https://www.readbyqxmd.com/read/30147245/regional-frequency-variation-of-revascularization-procedures-for-carotid-stenosis-in-germany-secondary-data-analysis-of-drg-data-from-2012-to-2014
#5
A Kuehnl, M Salvermoser, E Knipfer, A Zimmermann, V Schmid, H-H Eckstein
Background: For Germany, regional variation of procedure rates of carotid endarterectomy (CEA) and carotid artery stenting (CAS) performed for carotid stenosis have so far not been analyzed at a national level. The aim of this study was to assess small area estimates of procedure rates among German regions, and to identify regional characteristics, which are associated with the regional frequency of procedures. Methods: German diagnosis-related groups (DRG) statistics (2012-2014) were analyzed...
2018: Gefässchirurgie: Zeitschrift Für Vaskuläre und Endovaskuläre Chirurgie
https://www.readbyqxmd.com/read/30147244/the-marine-omega3-wound-matrix-for-treatment-of-complicated-wounds-a-multicenter-experience-report
#6
REVIEW
B Dorweiler, T T Trinh, F Dünschede, C F Vahl, E S Debus, M Storck, H Diener
Introduction: The Kerecis™ Omega3 Wound matrix is a decellularized skin matrix derived from fish skin and represents an innovative concept to achieve wound healing. The aim of this study was to report the cumulative experience of three centers for vascular surgery regarding use of the Omega3 Wound matrix in selected patients with complicated wounds. Material and methods: In this study 23 patients with 25 vascular and/or diabetes mellitus-associated complicated wounds and partially exposed bony segments were treated with the Omega3 Wound matrix in three vascular centers...
2018: Gefässchirurgie: Zeitschrift Für Vaskuläre und Endovaskuläre Chirurgie
https://www.readbyqxmd.com/read/30147243/staged-procedures-for-prevention-of-spinal-cord-ischemia-in-endovascular-aortic-surgery
#7
REVIEW
F Heidemann, N Tsilimparis, F Rohlffs, E S Debus, A Larena-Avellaneda, S Wipper, T Kölbel
Background: Spinal cord ischemia with development of paraplegia is the most relevant complication of thoracoabdominal aortic surgery caused by compromising the segmental arteries. To prevent this devastating complication in endovascular aortic surgery, staging procedures have been developed to reinforce collateral blood flood to the spinal cord. Results: In patients with a medium to high risk for spinal cord ischemia, staged aortic repair is recommended. The classical staged repair is the two-step repair with delayed implantation of the aortic stent grafts...
2018: Gefässchirurgie: Zeitschrift Für Vaskuläre und Endovaskuläre Chirurgie
https://www.readbyqxmd.com/read/29950794/complex-endovascular-treatment-of-intact-aortic-aneurysms-an-analysis-of-health-insurance-claims-data
#8
REVIEW
C-A Behrendt, H C Rieß, T Schwaneberg, F Heidemann, N Tsilimparis, A-A Larena-Avellaneda, H Diener, T Kölbel, E S Debus
Background: The complex endovascular repair of aortic aneurysms and dissections with fenestrated or branched stent grafts (FB-EVAR) remains challenging for interventional vascular surgery. To date, the evidence regarding treatment patterns and outcome measures consists of single center studies; however, it might be reasonable to validate results with multicenter real-world evidence. Methods: Health insurance claims data from Germany's third largest insurance provider, DAK-Gesundheit, were used to determine outcomes following FB-EVAR of non-ruptured thoracic aorta (TA) or thoracoabdominal including pararenal abdominal (TAA) aorta...
2018: Gefässchirurgie: Zeitschrift Für Vaskuläre und Endovaskuläre Chirurgie
https://www.readbyqxmd.com/read/29950793/the-incidence-of-incisional-hernia-after-aortic-aneurysm-is-not-higher-than-after-benign-colorectal-interventions-a-retrospective-control-matched-cohort-study
#9
REVIEW
A Wiegering, D Liebetrau, S Menzel, C Bühler, R Kellersmann, U A Dietz
Background: Abdominal aortic aneurysms (AAA) have most probably an inflammatory origin, whereby the elastica is the layer actually involved. In the past, collagen weackness was supposed to be the shared cause of both, AAA and incisional hernias. Since the development of new techniques of closure of the abdominal wall over the last decade, collagen deficency seems to play only a secondary etiologic role. Objectives: The aim of the study was to investigate whether the incidence of incisional hernia following laparotomy due to AAA differs from that of colorectal interventions...
2018: Gefässchirurgie: Zeitschrift Für Vaskuläre und Endovaskuläre Chirurgie
https://www.readbyqxmd.com/read/29950792/visceral-artery-aneurysms
#10
REVIEW
B Juntermanns, J Bernheim, K Karaindros, M Walensi, J N Hoffmann
Visceral artery aneurysms are rare with an incidence of only 0.01-0.1% of the population. Open surgical or endovascular elimination should be performed for aneurysms greater than 2 cm in size. The risk of aneurysm rupture is then approximately 25-40%. If the aneurysm ruptures the mortality can be as high as 76%. For mycotic aneurysms or spurious aneurysms there is no lower limit to the diameter size for the need of treatment. Sudden abdominal pain during pregnancy can be caused by visceral artery aneurysms and must be further clarified...
2018: Gefässchirurgie: Zeitschrift Für Vaskuläre und Endovaskuläre Chirurgie
https://www.readbyqxmd.com/read/29950791/pathophysiology-of-chronic-limb-ischemia
#11
REVIEW
F Simon, A Oberhuber, N Floros, P Düppers, H Schelzig, M Duran
Chronic ischemia of the lower extremities is an everyday problem in vascular surgery clinics. In Germany, approximately 3% of all hospitalizations are due to peripheral artery disease (PAD), with critical limb ischemia (CLI) in particular showing a rapid increase. The consequences of chronic undersupply range from reduced walking distance to loss of limbs. At the beginning there are stress factors, such as hyperlipidemia (LDL), free radicals, arterial hypertension, infections or subclinical inflammation that interfere with endothelial homeostasis and cause endothelial dysfunction with increased permeability...
2018: Gefässchirurgie: Zeitschrift Für Vaskuläre und Endovaskuläre Chirurgie
https://www.readbyqxmd.com/read/29950790/noninvasive-measurements-of-tissue-perfusion-in-critical-limb-ischemia
#12
REVIEW
U Rother, W Lang
Critical limb ischemia (CLI) remains a challenge for an interdisciplinary therapeutic team due to chronic nonhealing wounds. Against this background, there is a necessity of quality control after revascularization. Beside the isolated evaluation of the macrocirculation by Ankle-Brachial or Toe-Brachial Index measurements, the microcirculation as an additional important factor of wound healing often remains underestimated. The following article gives an overview about the current investigation methods for noninvasive perfusion control of the CLI patient...
2018: Gefässchirurgie: Zeitschrift Für Vaskuläre und Endovaskuläre Chirurgie
https://www.readbyqxmd.com/read/29950789/comparison-of-long-term-results-of-carotid-endarterectomy-for-asymptomatic-carotid-artery-stenosis
#13
REVIEW
S Demirel, D Böckler, M Storck
This article summarizes the current study situation on treatment of asymptomatic carotid artery stenosis and discusses the evidence situation in the literature. The 10-year results of the ACST study have shown that in comparison to conservative treatment, carotid endarterectomy (CEA) has retained a positive long-term effect on the reduction of all forms of stroke. All multicenter randomized controlled trials comparing CEA with carotid artery stenting (CAS) and, in particular the SAPHIRE and CAVATAS studies, have in common that despite a basic evidence level of Ib, the case numbers of asymptomatic patients are too small for a conclusive therapy recommendation...
2018: Gefässchirurgie: Zeitschrift Für Vaskuläre und Endovaskuläre Chirurgie
https://www.readbyqxmd.com/read/28944782/perioperative-cerebrospinal-fluid-drainage-for-the-prevention-of-spinal-ischemia-after-endovascular-aortic-repair
#14
M Wortmann, D Böckler, P Geisbüsch
Endovascular treatment of thoracic and thoracoabdominal aortic diseases is accompanied by a risk of spinal ischemia in 1-19% of patients, depending on the entity and extent of the disease. The use of perioperative drainage of cerebrospinal fluid is one of the invasive measures to reduce the occurrence of this severe complication. This article reviews the incidence of spinal ischemia, its risk factors, the evidence for carrying out cerebrospinal fluid drainage and its modern use by means of an automated, pressure controlled system (LiquoGuard®7)...
2017: Gefässchirurgie: Zeitschrift Für Vaskuläre und Endovaskuläre Chirurgie
https://www.readbyqxmd.com/read/28715514/i-swot-as-instrument-to-individually-optimize-therapy-of%C3%A2-thoracoabdominal-aortic-aneurysms-effective-norm-compliant-and-meeting-the-needs
#15
A Sachweh, Y von Kodolitsch, T Kölbel, A Larena-Avellaneda, S Wipper, A M Bernhardt, E Girdauskas, C Detter, H Reichenspurner, C R Blankart, E S Debus
BACKGROUND: Guidelines summarize medical evidence, they identify the most efficient therapy under study conditions and recommend this therapy for use. The physician now has the challenge to translate a therapy that is efficient under laboratory conditions to a patient who is an individual person. To accomplish this task the physician has to make sure that (I) the ideal typical therapy is applicable and effective in this individual patient taking the special features into consideration, that (II) therapy is compliant with the norm including guidelines, laws and ethical requirements (conformity) and that (III) the therapy meets the patient's needs...
2017: Gefässchirurgie: Zeitschrift Für Vaskuläre und Endovaskuläre Chirurgie
https://www.readbyqxmd.com/read/28715513/percutaneous-endovascular-treatment-of-infrainguinal-paod-results-of-the-psi-register-study-in-74%C3%A2-german-vascular-centers
#16
C-A Behrendt, F Heidemann, K Haustein, R T Grundmann, E S Debus
BACKGROUND: The percutaneous infrainguinal stent (PSI) register study aimed to collate all percutaneous endovascular procedures for infrainguinal peripheral arterial occlusive disease (PAOD) conducted in 74 German vascular centers between September and November 2015 (3 months). In order to obtain representative results all consecutive treatment procedures had to be submitted by the participating trial centers. MATERIAL AND METHODS: This was a prospective, nonrandomized multicenter study design...
2017: Gefässchirurgie: Zeitschrift Für Vaskuläre und Endovaskuläre Chirurgie
https://www.readbyqxmd.com/read/28715512/mouse-models-of-deep-vein-thrombosis
#17
T Schönfelder, S Jäckel, P Wenzel
The pathogenesis of venous thromboembolism (VTE) is still not completely understood. Experimental animals in which human deep vein thrombosis can be modeled are useful tools to investigate the pathogenesis of VTE. Besides the availability of transgenic and genetically modified mice, the use of high frequency ultrasound and intravital microscopy plays an important role in identifying thrombotic processes in mouse models. In this article, an overview about the application of various new technologies and existing mouse models is provided, and the impact of venous side branches on deep vein thrombosis in the mouse model is discussed...
2017: Gefässchirurgie: Zeitschrift Für Vaskuläre und Endovaskuläre Chirurgie
https://www.readbyqxmd.com/read/28715511/endovascular-treatment-of-genetically-linked-aortic-diseases
#18
D Böckler, K Meisenbacher, A S Peters, C Grond-Ginsbach, M S Bischoff
BACKGROUND: The most important structural proteins of the vascular wall are collagen and elastin. Genetically linked connective tissue diseases lead to degeneration, aneurysm formation and spontaneous dissection or rupture of arteries. The most well-known are Marfan syndrome, vascular Ehlers-Danlos syndrome (type IV), Loeys-Dietz syndrome and familial aortic aneurysms and dissections. OBJECTIVE: This review article addresses the current status of endovascular treatment options for important connective tissue diseases...
2017: Gefässchirurgie: Zeitschrift Für Vaskuläre und Endovaskuläre Chirurgie
https://www.readbyqxmd.com/read/28529410/quality-of-life-in-patients-with-intermittent-claudication
#19
A E Harwood, J P Totty, E Broadbent, G E Smith, I C Chetter
BACKGROUND: Intermittent claudication (IC) is a common condition that causes pain in the lower limbs when walking and has been shown to severely impact the quality of life (QoL) of patients. The QoL is therefore often regarded as an important measure in clinical trials investigating intermittent claudication. To date, no consensus exits on the type of life questionnaire to be used. This review aims to examine the QoL questionnaires used in trials investigating peripheral arterial disease (PAD)...
2017: Gefässchirurgie: Zeitschrift Für Vaskuläre und Endovaskuläre Chirurgie
https://www.readbyqxmd.com/read/27551877/results-of-peripheral-bypass-surgery-in-patients-with-critical-limb-ischemia-critisch-registry
#20
T Bisdas, G Torsello, A Stachmann, R T Grundmann
AIM: On the basis of the CRITISCH registry outcomes in patients with critical limb ischemia (CLI) undergoing lower extremity bypass surgery were analyzed according to the site of distal anastomosis and type of bypass material. PATIENTS AND METHODS: A total of 284 patients with lower extremity bypasses consisting of 75 patients with bypasses above the knee (group 1), 80 with bypasses below the knee (group 2) and 129 crural or pedal bypasses (group 3) were included in the study...
2016: Gefässchirurgie: Zeitschrift Für Vaskuläre und Endovaskuläre Chirurgie
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