journal
MENU ▼
Read by QxMD icon Read
search

Audiology & Neuro-otology

journal
https://www.readbyqxmd.com/read/29332068/the-role-of-preoperative-steroids-for-hearing-preservation-cochlear-implantation-results-of-a-randomized-controlled-trial
#1
Jafri Kuthubutheen, Samidha Joglekar, Leah Smith, Lendra Friesen, Kari Smilsky, Tara Millman, Amy Ng, David Shipp, Harvey Coates, Christoph Arnoldner, Julian Nedzelski, Joseph Chen, Vincent Lin
OBJECTIVES: To determine whether preoperative steroids can improve hearing outcomes in cochlear implantation (CI). METHODS: This is a randomized controlled trial involving 30 postlingual deaf CI patients. Subjects had preoperative thresholds of better than or equal to 80 dB at 125 and 250 Hz, and better than or equal to 90 dB at 500 and 1,000 Hz. The subjects were randomized to a control group, an oral steroid group (receiving 1 mg/kg/day of prednisolone for 6 days prior to surgery), or a transtympanic steroid group (receiving a single dose of 0...
January 13, 2018: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29324449/toward-optimizing-vestibular-evoked-myogenic-potentials-normalization-reduces-the-need-for-strong-neck-muscle-contraction
#2
Kimberley S Noij, Barbara S Herrmann, Steven D Rauch, John J Guinan
BACKGROUND: The cervical vestibular evoked myogenic potential (cVEMP) represents an inhibitory reflex of the saccule measured in the ipsilateral sternocleidomastoid muscle (SCM) in response to acoustic or vibrational stimulation. Since the cVEMP is a modulation of SCM electromyographic (EMG) activity, cVEMP amplitude is proportional to muscle EMG amplitude. We sought to evaluate muscle contraction influences on cVEMP peak-to-peak amplitudes (VEMPpp), normalized cVEMP amplitudes (VEMPn), and inhibition depth (VEMPid)...
January 12, 2018: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29298446/effect-of-cochlear-implantation-on-quality-of-life-in-adults-with-unilateral-hearing-loss
#3
Margaret T Dillon, Emily Buss, Meredith A Rooth, English R King, Ellen J Deres, Craig A Buchman, Harold C Pillsbury, Kevin D Brown
OBJECTIVE: Patients with moderate-to-profound sensorineural hearing loss in 1 ear and normal hearing in the contralateral ear, known as unilateral hearing loss (UHL) or single-sided deafness (SSD), may experience improved quality of life with the use of a cochlear implant (CI) in the affected ear. Quality of life assessment before and after implantation may reveal changes to aspects of hearing beyond those explicitly evaluated with behavioral measures. METHODS: The present report completed 2 experiments investigating quality of life outcomes in CI recipients with UHL...
January 4, 2018: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29262414/quality-of-life-and-cost-effectiveness-of-cochlear-implants-a-narrative-review
#4
Matthew G Crowson, Yevgeniy R Semenov, Debara L Tucci, John K Niparko
OBJECTIVES: To review evidence regarding the health-related quality of life (HRQoL) and cost-effectiveness of unilateral and bilateral cochlear implantation (CI) among children and adults with severe-to-profound hearing loss. STUDY DESIGN: Narrative review. METHODS: Publications related to quality of life (QoL) and costs of care in CI were acquired through searches in English-language databases. Studies were included if they had identified the HRQoL attainment, cost of care, cost-utility, or cost-effectiveness associated with CI...
December 21, 2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29232662/a-multicenter-clinical-evaluation-of-data-logging-in-cochlear-implant-recipients-using-automated-scene-classification-technologies
#5
Eliana Cristofari, Domenico Cuda, Alessandro Martini, Francesca Forli, Diego Zanetti, Diego Di Lisi, Pasquale Marsella, Daniele Marchioni, Vincenzo Vincenti, Claudia Aimoni, Gaetano Paludetti, Maria Grazia Barezzani, Carlo Antonio Leone, Nicola Quaranta, Marco Bianchedi, Livio Presutti, Antonio Della Volpe, Luca Oscar Redaelli de Zinis, Italo Cantore, Giuseppe Nicolò Frau, Eva Orzan, Francesco Galletti, Silvano Vitale, Ferdinando Raso, Maurizio Negri, Franco Trabalzini, Walter Livi, Lucia Oriella Piccioni, Giampietro Ricci, Paolo Malerba
Currently, there are no studies assessing everyday use of cochlear implant (CI) processors by recipients by means of objective tools. The Nucleus 6 sound processor features a data logging system capable of real-time recording of CI use in different acoustic environments and under various categories of loudness levels. In this study, we report data logged for the different scenes and different loudness levels of 1,366 CI patients, as recorded by SCAN. Monitoring device use in cochlear implant recipients of all ages provides important information about the listening conditions encountered in recipients' daily lives that may support counseling and assist in the further management of their device settings...
December 13, 2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29224005/evidence-of-osteoclastic-activity-in-the-human-temporal-bone
#6
Takefumi Kamakura, Joseph B Nadol
Bone remodeling within the otic capsule has been reported to be inhibited especially at or near the cochlea, except under some pathological conditions such as otosclerosis, Paget's disease, or mastoiditis, when bone remodeling can occur. Microcavitations found in periosteal and endosteal layers of human temporal bone specimens without otosclerosis, Paget's disease, or inflammation as reported in the current study are consistent with osteoclastic bone resorption. Thirty-three temporal bones from 33 patients were prepared for light microscopy and classified into 4 groups: histologically proven dehiscence of the superior semicircular canal (SSCD) (n = 3, group 1), age 20 years or younger (n = 10, group 2), age 90 years or older and with otosclerosis (n = 10, group 3), and age 90 years or older without otosclerosis (n = 10, group 4)...
December 9, 2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29166635/the-protean-neuropsychiatric-and-vestibuloauditory-manifestations-of-neurosarcoidosis
#7
Jacqueline J Greene, Ilka C Naumann, Janet M Poulik, Kevin T Nella, Lindsay Weberling, Jeffrey P Harris, Akihiro J Matsuoka
BACKGROUND: A rare subset of sarcoidosis, neurosarcoidosis, is reported to occur in 5-7% of sarcoid patients and can manifest in a variety of ways. The most common are facial paralysis and optic neuritis, less commonly causing cochleovestibulopathy, blindness, anosmia, and other cranial nerve (CN) palsies. The sensory deficit may be severe and psychiatric symptoms may result from the effects of the disease or steroid treatment. Although MRI-compatible cochlear implants are now available, concerns about the feasibility of recoverable hearing with cochlear implantation in these patients as well as the practical difficulty of disease monitoring due to implant artifact must be considered...
November 23, 2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29130955/tinnitus-and-hearing-survey-a-polish-study-of-validity-and-reliability-in-a-clinical-population
#8
Danuta Raj-Koziak, Elzbieta Gos, Joanna Rajchel, Adam Piłka, Henryk Skarżyński, Joanna Rostkowska, Piotr H Skarzynski
This study investigates the psychometric properties of the Polish version of the Tinnitus and Hearing Survey (THS-POL), which is a tool for evaluating what proportion of patients' tinnitus is due to hearing problems and what proportion is specifically due to the tinnitus. The THS-POL was created using the translation-backtranslation method. Study participants completed the THS-POL twice over a period of 3 days. The test-retest analysis shows excellent strength of correlations (THS-POL subscale A r = 0.89, subscale B r = 0...
November 11, 2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29084395/electrophysiological-evidence-of-the-basilar-membrane-travelling-wave-and-frequency-place-coding-of-sound-in-cochlear-implant-recipients
#9
Luke Campbell, Christofer Bester, Claire Iseli, David Sly, Adrian Dragovic, Anthony W Gummer, Stephen O'Leary
AIM: To obtain direct evidence for the cochlear travelling wave in humans by performing electrocochleography from within the cochlea in subjects implanted with an auditory prosthesis. BACKGROUND: Sound induces a travelling wave that propagates along the basilar membrane, exhibiting cochleotopic tuning with a frequency-dependent phase delay. To date, evoked potentials and psychophysical experiments have supported the presence of the travelling wave in humans, but direct measurements have not been made...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29080887/evaluation-of-vestibular-functions-in-patients-with-vogt-koyanagi-harada-disease
#10
Keishi Fujiwara, Shinya Morita, Kimiko Hoshino, Atsushi Fukuda, Yuji Nakamaru, Akihiro Homma
Vogt-Koyanagi-Harada (VKH) disease is an idiopathic, multisystem autoimmune disorder characterized by bilateral, diffuse granulomatous uveitis associated with neurological, audiovestibular, and dermatological manifestations. The purpose of this study is to investigate vestibular functions in patients with VKH disease. A total of 43 patients with VKH disease in Hokkaido University Hospital were enrolled in this study. Subjective symptoms such as dizziness or vertigo and the results of various vestibular examinations including nystagmus testing, caloric testing, and vestibular-evoked myogenic potential (VEMP) testing were investigated...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29059669/clinical-investigation-of-the-nucleus-slim-modiolar-electrode
#11
Antje Aschendorff, Robert Briggs, Goetz Brademann, Silke Helbig, Joachim Hornung, Thomas Lenarz, Mathieu Marx, Angel Ramos, Timo Stöver, Bernard Escudé, Chris J James
AIMS: The Nucleus CI532 cochlear implant incorporates a new precurved electrode array, i.e., the Slim Modiolar electrode (SME), which is designed to bring electrode contacts close to the medial wall of the cochlea while avoiding trauma due to scalar dislocation or contact with the lateral wall during insertion. The primary aim of this prospective study was to determine the final position of the electrode array in clinical cases as evaluated using flat-panel volume computed tomography...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29049998/endoplasmic-reticulum-stress-is-involved-in-cochlear-cell-apoptosis-in-a-cisplatin-induced-ototoxicity-rat-model
#12
Shimin Zong, Tianyi Liu, Fangmin Wan, Pei Chen, Pan Luo, Hongjun Xiao
Endoplasmic reticulum (ER) stress arises when excessive improperly folded proteins accumulate in the ER lumen. When ER stress occurs, the unfolded protein response (UPR) is subsequently activated to restore ER proteostasis. However, severe ER stress leads to apoptosis. Recent studies have suggested that cisplatin cytotoxicity may be related to ER stress. The purpose of this study was to determine whether ER stress participates in cochlear cell apoptosis in a cisplatin-induced ototoxicity rat model and to also determine the possible relationship between ER stress and hearing loss...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/28992622/a-subjective-rating-scale-for-initial-assessment-of-sudden-unilateral-sensorineural-hearing-loss
#13
Omer J Ungar, Oren Cavel, Yahav Oron, Anat Wengier, Oshri Wasserzug, Ophir Handzel
OBJECTIVE: To examine the value of a subjective numerical rating scale (NRS) in the initial evaluation of patients suspected of suffering from unilateral sudden sensorineural hearing loss (SSNHL) until a formal audiogram is available. STUDY DESIGN: Prospective noncontrolled clinical study. METHODS: Thirty-one consecutive patients referred to the emergency department due to suspected unilateral SSNHL and with no other aural pathology by history or physical examination were enrolled...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/28982105/impact-of-lipid-inflammatory-oxidative-metabolism-on-auditory-skills-after-hearing-aid-fitting-in-the-elderly
#14
Alexandre Hundertmarck Lessa, Ivana Beatrice Mânica da Cruz, Maria Fernanda Manica-Cattani, Rafael Noal Moresco, Marta Maria Medeiros Frescura Duarte, Maristela Julio Costa
This study aimed to assess whether lipid-inflammatory-oxidative metabolism influences auditory processing skills, and whether they function in changing auditory performance after hearing aid fitting in the elderly. Twelve subjects with bilateral hearing loss were submitted to blood tests (to check their lipid-inflammatory-oxidative metabolism) and auditory processing skill tests. After 3 months of using the hearing aids, their auditory skills were re-evaluated and the data were correlated statistically. Oxidative stress levels mainly showed some impact on auditory temporal processing; such a relation and others should best be examined in further studies with larger populations...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/28968605/expression-profiling-of-micrornas-in-the-inner-ear-of-elderly-people-by-real-time-pcr-quantification
#15
Kuwon Sekine, Tomohiro Matsumura, Toshihiro Takizawa, Yurika Kimura, Shiho Saito, Kyoko Shiiba, Susumu Shindo, Kimihiro Okubo, Tetsuo Ikezono
The molecular mechanisms underlying age-related hearing loss are unknown, and currently, there is no treatment for this condition. Recent studies have shown that microRNAs (miRNAs) and age-related diseases are intimately linked, suggesting that some miRNAs may present attractive therapeutic targets. In this study, we obtained 8 human temporal bones from 8 elderly subjects at brain autopsy in order to investigate the expression profile of miRNAs in the inner ear with miRNA arrays. A mean of 478 different miRNAs were expressed in the samples, of which 348 were commonly expressed in all 8 samples...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/28889125/brimonidine-protects-auditory-hair-cells-from-in-vitro-induced-toxicity-of-gentamicin
#16
Maurizio Cortada, Soledad Levano, Daniel Bodmer
Brimonidine, an alpha-2 adrenergic receptor (α2-AR) agonist, has neuroprotective effects in the visual system and in spiral ganglion neurons. Auditory hair cells (HCs) express all 3 α2-AR subtypes, but their roles in HCs remain unknown. This study investigated the effects of brimonidine on auditory HCs that were also exposed to gentamicin, which is toxic to HCs. Organ of Corti explants were exposed to gentamicin in the presence or absence of brimonidine, and the α2-AR protein expression levels and Erk1/2 and Akt phosphorylation levels were determined...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/28848089/histopathology-of-the-human-inner-ear-in-the-cogan-syndrome-with-cochlear-implantation
#17
Takefumi Kamakura, Daniel J Lee, Barbara S Herrmann, Joseph B Nadol
The Cogan syndrome is a rare disorder characterized by nonsyphilitic interstitial keratitis and audiovestibular symptoms. Profound sensorineural hearing loss has been reported in approximately half of the patients with the Cogan syndrome resulting in candidacy for cochlear implantation in some patients. The current study is the first histopathologic report on the temporal bones of a patient with the Cogan syndrome who during life underwent bilateral cochlear implantation. Preoperative MRI revealed tissue with high density in the basal turns of both cochleae and both vestibular systems consistent with fibrous tissue due to labyrinthitis...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/28848077/perception-of-iterated-rippled-noise-periodicity-in-cochlear-implant-users
#18
Luise Wagner, Stefan K Plontke, Torsten Rahne
Pitch perception is more challenging for individuals with cochlear implants (CIs) than normal-hearing subjects because the signal processing by CIs is restricted. Processing and perceiving the periodicity of signals may contribute to pitch perception. Whether individuals with CIs can discern pitch within an iterated rippled noise (IRN) signal is still unclear. In a prospective controlled psychoacoustic study with 34 CI users and 15 normal-hearing control subjects, the difference limen between IRN signals with different numbers of iterations was measured...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/28817812/the-mir-34a-bcl-2-pathway-contributes-to-auditory-cortex-neuron-apoptosis-in-age-related-hearing-loss
#19
Qiuhong Huang, Yongkang Ou, Hao Xiong, Haidi Yang, Zhigang Zhang, Suijun Chen, Yongyi Ye, Yiqing Zheng
HYPOTHESIS: The miR-34a/Bcl-2 signaling pathway may play a role in the mechanisms related to age-related hearing loss (AHL) in the auditory cortex. BACKGROUND: The auditory cortex plays a key role in the recognition and processing of complex sound. It is difficult to explain why patients with AHL have poor speech recognition, so increasing numbers of studies have focused on its central change. Although micro (mi)RNAs in the central nervous system have recently been increasingly reported to be associated with age-related diseases, the molecular mechanisms of AHL in the auditory cortex are not fully understood...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/28793285/resistance-of-gerbil-auditory-function-to-reversible-decrease-in-cochlear-blood-flow
#20
Fahd El Afia, Fabrice Giraudet, Laurent Gilain, Thierry Mom, Paul Avan
The objective was to design in gerbils a model of reversible decrease in cochlear blood flow (CBF) and analyze its influence on cochlear function. In Mongolian gerbils injected with ferromagnetic microbeads, a magnet placed near the porus acusticus allowed CBF to be manipulated. The cochlear microphonic potential (CM) from the basal cochlea was monitored by a round-window electrode. In 13 of the 20 successfully injected gerbils, stable CBF reduction was obtained for 11.5 min on average. The CM was affected only when CBF fell to less than 60% of its baseline, yet remained >40% of its initial level in about 2/3 of such cases...
2017: Audiology & Neuro-otology
journal
journal
32513
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"