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Audiology & Neuro-otology

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https://www.readbyqxmd.com/read/29953973/late-cochlear-implantation-in-early-deafened-adults-a-detailed-analysis-of-auditory-and-self-perceived-benefits
#1
Joke Debruyne, Miranda Janssen, Jan Brokx
OBJECTIVES: It is known that early-deafened cochlear implant (CI) users are a very heterogeneously performing group. To gain more insight into this population, this study investigated (1) postoperative changes in auditory performance over time based on various outcome measures, focusing on poor performers, (2) self-perceived outcomes, (3) relations between auditory and self-perceived outcomes, and (4) preimplantation factors predicting postoperative outcomes. METHODS: Outcomes were assessed prospectively in a group of 27 early-deafened, late-implanted CI users, up to 3 years after implantation...
June 28, 2018: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29936510/the-effect-of-binaural-beamforming-technology-on-speech-intelligibility-in-bimodal-cochlear-implant-recipients
#2
Jantien L Vroegop, Nienke C Homans, André Goedegebure, J Gertjan Dingemanse, Teun van Immerzeel, Marc P van der Schroeff
Although the benefit of bimodal listening in cochlear implant users has been agreed on, speech comprehension remains a challenge in acoustically complex real-life environments due to reverberation and disturbing background noises. One way to additionally improve bimodal auditory performance is the use of directional microphones. The objective of this study was to investigate the effect of a binaural beamformer for bimodal cochlear implant (CI) users. This prospective study measured speech reception thresholds (SRT) in noise in a repeated-measures design that varied in listening modality for static and dynamic listening conditions...
June 22, 2018: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29936507/abnormal-cochleovestibular-anatomy-and-hearing-outcomes-pediatric-patients-with-a-questionable-cochleovestibular-nerve-status-may-benefit-from-cochlear-implantation-and-or-hearing-aids
#3
Elina Kari, John L Go, Janice Loggins, Neelmini Emmanuel, Laurel M Fisher
OBJECTIVE: Imaging characteristics and hearing outcomes in children with cochleovestibular or cochleovestibular nerve (CVN) abnormalities. STUDY DESIGN: Retrospective, critical review. SETTING: Tertiary referral academic center. PATIENTS: Twenty-seven children with CVN abnormalities with magnetic resonance (MRI) and/or computed tomography (CT). Study Intervention(s): None. MAIN OUTCOME MEASURE(S): Determine the likely presence or absence of a CNV and auditory stimulation responses...
June 22, 2018: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29936500/cochlear-nerve-aplasia-with-detectable-olivocochlear-efferent-function-a-distinct-presentation-of-auditory-neuropathy-spectrum-disorder
#4
Adrian L James, Peter R Dixon, Robert V Harrison
BACKGROUND: Cochlear nerve aplasia (CNA) may present with features of auditory neuropathy spectrum disorder (ANSD), having detectable otoacoustic emissions (OAE) but profound hearing loss. We propose that some children with CNA have a distinct form of afferent ANSD in which efferent cochlear nerve function can be detected using contralateral suppression of OAE. METHODS: Children were prospectively enrolled with MRI and auditory brainstem response evidence of unilateral CNA, a normal contralateral ear, and detectable OAE bilaterally...
June 22, 2018: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29929192/effect-of-antioxidant-vitamins-as-adjuvant-therapy-for-sudden-sensorineural-hearing-loss-systematic-review-study
#5
REVIEW
Iman Ibrahim, Anthony Zeitouni, Sabrina Daniela da Silva
IMPORTANCE: Sudden sensorineural hearing loss (SSNHL) is an otological emergency of unknown etiology. Recent reports showed that antioxidant drugs can benefit patients with SSNHL. This study attempted to evaluate the effect of adding antioxidant vitamins as an adjuvant therapy alongside with corticosteroids. OBJECTIVE: To evaluate the effects of the 3 major antioxidant vitamins (A, C, and E) as an adjuvant therapy, administered with corticosteroids, for the treatment of SSNHL in adult patients (≥18 years)...
June 22, 2018: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29929200/methionine-sulfoxide-reductase-a-knockout-mice-show-progressive-hearing-loss-and-sensitivity-to-acoustic-trauma
#6
Safa Alqudah, Mark Chertoff, Dianne Durham, Jackob Moskovitz, Hinrich Staecker, Marcello Peppi
Methionine sulfoxide reductases (MsrA and MsrB) protect the biological activity of proteins from oxidative modifications to methionine residues and are important for protecting against the pathological effects of neurodegenerative diseases. In the current study, we characterized the auditory phenotype of the MsrA knockout mouse. Young MsrA knockout mice showed small high-frequency threshold elevations for auditory brainstem response and distortion product otoacoustic emission compared to those of wild-type mice, which progressively worsened in older MsrA knockout mice...
June 21, 2018: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29929187/one-year-results-for-patients-with-unilateral-hearing-loss-and-accompanying-severe-tinnitus-and-hyperacusis-treated-with-a-cochlear-implant
#7
Angel Ramos Macías, Juan Carlos Falcón-González, Manuel Manrique Rodríguez, Constantino Morera Pérez, Luis García-Ibáñez, Carlos Cenjor Español, Chrystelle Coudert-Koall, Matthijs Killian
OBJECTIVE: To show that patients with unilateral hearing loss (UHL), with one ear fulfilling cochlear implant (CI) indication criteria, and an additional severe tinnitus handicap can be treated effectively with a CI. METHOD: A prospective multi-centre study was conducted in five Spanish centres. Sixteen adult patients with UHL and a mean Tinnitus Handicap Inventory (THI) score of at least 58 were implanted. The study design included repeated within-subject measures of quality of life (Health Utility Index Mark 3 [HUI3]), tinnitus (THI, Visual Analogue Scale [VAS] on tinnitus loudness), hearing (Speech, Spatial, and Qualities of Hearing Scale- [SSQ]), and hyperacusis (Test de Hipersensibilidad al Sonido [THS]) up to 12 months after the initial CI fitting...
June 21, 2018: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29719297/predicting-sequential-cochlear-implantation-performance-a-systematic-review
#8
Yvette Smulders, Thomas Hendriks, Robert Eikelboom, Inge Stegeman, Peter Santa Maria, Marcus Atlas, Peter Friedland
This systematic review of the literature reveals which pre-operative factors affect sequential cochlear implantation outcomes in adults. The findings can help health care prof-essionals provide evidence-based advice on the expected benefits from a second cochlear implant (CI). We searched PubMed, EMBASE, and the Cochrane database from November 1977 to August 26, 2017, using the terms "sequential cochlear implantation"; the most frequently cited predictors for unilateral cochlear implantation performance and other potential predictors for sequential implantation outcome; and "speech perception," "localization" as well as synonyms of all of the above...
May 2, 2018: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29698956/long-term-hearing-outcomes-following-stapedotomy-in-patients-with-otosclerosis-and-preoperative-small-air-bone-gap
#9
Anna Alberti, Enric Figuerola, Guillermo Romero-Farina, Miquel Quer, Francisco Larrosa
OBJECTIVES: To assess the long-term effectiveness of stapedotomies performed on patients with otosclerosis and preoperative small air-bone gaps (ABGs). METHODS: Retrospective study comparing the 10-year postoperative hearing outcomes after primary stapedotomies in patients with small (≤20 dB) and large ABGs (> 20 dB). Ninety out of 175 stapedotomies (22 and 68 in the small and large ABG groups, respectively) were monitored with long-term follow-ups. RESULTS: Ten years after the operation, hearing measurements were similar for both groups, although a significant decline of bone conduction thresholds was evident (p = 0...
April 26, 2018: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29649793/long-term-effects-of-middle-ear-tendon-resection-on-middle-ear-myoclonic-tinnitus-hearing-and-hyperacusis
#10
Dong-Kee Kim, Jung Mee Park, Jung Ju Han, Yun Min Chung, Jung Min Kim, So Young Park, Shi Nae Park
OBJECTIVE: To evaluate the therapeutic effects of middle ear tendon resection (METR) on middle ear myoclonic tinnitus (MEMT) and to investigate its long-term effects on hearing and hyperacusis. MATERIALS AND METHODS: Thirty-seven patients with MEMT with a mean age of 33.2 ± 11.8 years were included in this study. METR was performed on all 37 MEMT patients (41 ears) between November 2004 and August 2016. The mean follow-up period was 16.1 months. We examined changes in tinnitus and accompanying stress and depression in patients after surgery, and examined the hearing changes and the occurrence of complications including hyperacusis...
April 12, 2018: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29495018/localization-and-spatial-discrimination-in-children-and-adolescents-with-moderate-sensorineural-hearing-loss-tested-without-their-hearing-aids
#11
Sylvia Meuret, Alexandra Annemarie Ludwig, Dorothee Predel, Burkhard Staske, Michael Fuchs
The present study investigated two measures of spatial acoustic perception in children and adolescents with sensorineural hearing loss (SNHL) tested without their hearing aids and compared it to age-matched controls. Auditory localization was quantified by means of a sound source identification task and auditory spatial discrimination acuity by measuring minimum audible angles (MAA). Both low- and high-frequency noise bursts were employed in the tests to separately address spatial auditory processing based on interaural time and intensity differences...
March 1, 2018: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29486475/hearing-preservation-with-the-slim-modiolar-electrode-nucleus-ci532%C3%A2-cochlear-implant-a-preliminary-experience
#12
Angel Ramos-Macías, S A Borkoski-Barreiro, J C Falcón-González, A Ramos-de Miguel
As the indications for cochlear implant have expanded to include younger patients and individuals with greater degrees of residual hearing, increasing emphasis has been placed on atraumatic surgery and the preservation of the cochlear structure. Here, a descriptive prospective randomized study was performed. It was shown that residual hearing preservation is possible 12 months postoperatively with an atraumatic perimodiolar flexible electrode array CI532® (Cochlear Ltd, Sydney, Australia). Residual hearing preservation, considered as < 15 dB, was obtained in 70% of the cases...
February 27, 2018: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29462815/a-trend-in-sudden-sensorineural-hearing-loss-data-from-a-population-based-study
#13
Shin Hye Kim, Su-Jong Kim, Hwibin Im, Tae-Hun Kim, Jae-Jun Song, Sung-Won Chae
This is the first study reporting on the incidence and clinical aspects of sudden sensorineural hearing loss (SSNHL) in South Korea. Using Health Insurance Review and Assessment Service data from 2011 to 2015, the monthly incidence of unilateral SSNHL and incidence according to patients' sex, age, and month of diagnosis were investigated. The monthly incidence of unilateral SSNHL increased over the 5-year study period, with a mean annual incidence of 17.76 cases/ 100,000 of the population. The incidence increased with age, with most patients presenting in their 60s...
February 20, 2018: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29393101/resveratrol-promotes-recovery-of-hearing-following-intense-noise-exposure-by-enhancing-cochlear-sirt1-activity
#14
Hao Xiong, Yongkang Ou, Yaodong Xu, Qiuhong Huang, Jiaqi Pang, Lan Lai, Yiqing Zheng
The sirtuin SIRT1 is a highly conserved nicotinamide adenine dinucleotide (NAD)-dependent protein deacetylase known to have protective effects against a wide range of neurological disorders. In the present study, we discovered that C57BL/6 mice fed a long-term diet supplemented with high-dose resveratrol exhibited increased cochlear SIRT1 activity and presented a better recovery of hearing and less loss of hair cells after intense noise exposure compared with those fed a standard chew. Moreover, resveratrol attenuated cochlear SIRT1 decrease and reduced oxidative stress in the cochlea after noise exposure...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29342460/role-of-the-frontal-sinus-in-mediating-ocular-vestibular-evoked-myogenic-potentials-by-bone-vibration-stimuli-applied-to-the-forehead
#15
Kuei-You Lin, Te-Huei Yeh, Fu-Shan Jaw, Yi-Ho Young
This study investigated ocular vestibular-evoked myogenic potential (oVEMP) tests via Fpz and Fz taps to assess the role of the frontal sinus in mediating oVEMP elicitation. Forty healthy subjects and 80 patients with Ménière disease (MD) underwent a series of oVEMP tests via a minishaker tapping at the Fpz and Fz sites in a randomized order. Response rates of oVEMP test via various tapping sites were compared. Dimensions of the frontal sinus were measured via CT scan. A significantly negative correlation between the age and height of the frontal sinus was noted, and the cutoff age for discriminating present and absent Fpz oVEMPs in MD patients was 52 years...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29332068/the-role-of-preoperative-steroids-for-hearing-preservation-cochlear-implantation-results-of-a-randomized-controlled-trial
#16
Jafri Kuthubutheen, Samidha Joglekar, Leah Smith, Lendra Friesen, Kari Smilsky, Tara Millman, Amy Ng, David Shipp, Harvey Coates, Christoph Arnoldner, Julian Nedzelski, Joseph Chen, Vincent Lin
OBJECTIVES: To determine whether preoperative steroids can improve hearing outcomes in cochlear implantation (CI). METHODS: This is a randomized controlled trial involving 30 postlingual deaf CI patients. Subjects had preoperative thresholds of better than or equal to 80 dB at 125 and 250 Hz, and better than or equal to 90 dB at 500 and 1,000 Hz. The subjects were randomized to a control group, an oral steroid group (receiving 1 mg/kg/day of prednisolone for 6 days prior to surgery), or a transtympanic steroid group (receiving a single dose of 0...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29324449/toward-optimizing-vestibular-evoked-myogenic-potentials-normalization-reduces-the-need-for-strong-neck-muscle-contraction
#17
Kimberley S Noij, Barbara S Herrmann, Steven D Rauch, John J Guinan
BACKGROUND: The cervical vestibular evoked myogenic potential (cVEMP) represents an inhibitory reflex of the saccule measured in the ipsilateral sternocleidomastoid muscle (SCM) in response to acoustic or vibrational stimulation. Since the cVEMP is a modulation of SCM electromyographic (EMG) activity, cVEMP amplitude is proportional to muscle EMG amplitude. We sought to evaluate muscle contraction influences on cVEMP peak-to-peak amplitudes (VEMPpp), normalized cVEMP amplitudes (VEMPn), and inhibition depth (VEMPid)...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29298446/effect-of-cochlear-implantation-on-quality-of-life-in-adults-with-unilateral-hearing-loss
#18
Margaret T Dillon, Emily Buss, Meredith A Rooth, English R King, Ellen J Deres, Craig A Buchman, Harold C Pillsbury, Kevin D Brown
OBJECTIVE: Patients with moderate-to-profound sensorineural hearing loss in 1 ear and normal hearing in the contralateral ear, known as unilateral hearing loss (UHL) or single-sided deafness (SSD), may experience improved quality of life with the use of a cochlear implant (CI) in the affected ear. Quality of life assessment before and after implantation may reveal changes to aspects of hearing beyond those explicitly evaluated with behavioral measures. METHODS: The present report completed 2 experiments investigating quality of life outcomes in CI recipients with UHL...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29262414/quality-of-life-and-cost-effectiveness-of-cochlear-implants-a-narrative-review
#19
Matthew G Crowson, Yevgeniy R Semenov, Debara L Tucci, John K Niparko
OBJECTIVES: To review evidence regarding the health-related quality of life (HRQoL) and cost-effectiveness of unilateral and bilateral cochlear implantation (CI) among children and adults with severe-to-profound hearing loss. STUDY DESIGN: Narrative review. METHODS: Publications related to quality of life (QoL) and costs of care in CI were acquired through searches in English-language databases. Studies were included if they had identified the HRQoL attainment, cost of care, cost-utility, or cost-effectiveness associated with CI...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29232662/a-multicenter-clinical-evaluation-of-data-logging-in-cochlear-implant-recipients-using-automated-scene-classification-technologies
#20
Eliana Cristofari, Domenico Cuda, Alessandro Martini, Francesca Forli, Diego Zanetti, Diego Di Lisi, Pasquale Marsella, Daniele Marchioni, Vincenzo Vincenti, Claudia Aimoni, Gaetano Paludetti, Maria Grazia Barezzani, Carlo Antonio Leone, Nicola Quaranta, Marco Bianchedi, Livio Presutti, Antonio Della Volpe, Luca Oscar Redaelli de Zinis, Italo Cantore, Giuseppe Nicolò Frau, Eva Orzan, Francesco Galletti, Silvano Vitale, Ferdinando Raso, Maurizio Negri, Franco Trabalzini, Walter Livi, Lucia Oriella Piccioni, Giampietro Ricci, Paolo Malerba
Currently, there are no studies assessing everyday use of cochlear implant (CI) processors by recipients by means of objective tools. The Nucleus 6 sound processor features a data logging system capable of real-time recording of CI use in different acoustic environments and under various categories of loudness levels. In this study, we report data logged for the different scenes and different loudness levels of 1,366 CI patients, as recorded by SCAN. Monitoring device use in cochlear implant recipients of all ages provides important information about the listening conditions encountered in recipients' daily lives that may support counseling and assist in the further management of their device settings...
2017: Audiology & Neuro-otology
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