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Audiology & Neuro-otology

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https://www.readbyqxmd.com/read/29719297/predicting-sequential-cochlear-implantation-performance-a-systematic-review
#1
Yvette Smulders, Thomas Hendriks, Robert Eikelboom, Inge Stegeman, Peter Santa Maria, Marcus Atlas, Peter Friedland
This systematic review of the literature reveals which pre-operative factors affect sequential cochlear implantation outcomes in adults. The findings can help health care prof-essionals provide evidence-based advice on the expected benefits from a second cochlear implant (CI). We searched PubMed, EMBASE, and the Cochrane database from November 1977 to August 26, 2017, using the terms "sequential cochlear implantation"; the most frequently cited predictors for unilateral cochlear implantation performance and other potential predictors for sequential implantation outcome; and "speech perception," "localization" as well as synonyms of all of the above...
May 2, 2018: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29698956/long-term-hearing-outcomes-following-stapedotomy-in-patients-with-otosclerosis-and-preoperative-small-air-bone-gap
#2
Anna Alberti, Enric Figuerola, Guillermo Romero, Miquel Quer, Francisco Larrosa
OBJECTIVES: To assess the long-term effectiveness of stapedotomies performed on patients with otosclerosis and preoperative small air-bone gaps (ABGs). METHODS: Retrospective study comparing the 10-year postoperative hearing outcomes after primary stapedotomies in patients with small (≤20 dB) and large ABGs (> 20 dB). Ninety out of 175 stapedotomies (22 and 68 in the small and large ABG groups, respectively) were monitored with long-term follow-ups. RESULTS: Ten years after the operation, hearing measurements were similar for both groups, although a significant decline of bone conduction thresholds was evident (p = 0...
April 26, 2018: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29649793/long-term-effects-of-middle-ear-tendon-resection-on-middle-ear-myoclonic-tinnitus-hearing-and-hyperacusis
#3
Dong-Kee Kim, Jung Mee Park, Jung Ju Han, Yun Min Chung, Jung Min Kim, So Young Park, Shi Nae Park
OBJECTIVE: To evaluate the therapeutic effects of middle ear tendon resection (METR) on middle ear myoclonic tinnitus (MEMT) and to investigate its long-term effects on hearing and hyperacusis. MATERIALS AND METHODS: Thirty-seven patients with MEMT with a mean age of 33.2 ± 11.8 years were included in this study. METR was performed on all 37 MEMT patients (41 ears) between November 2004 and August 2016. The mean follow-up period was 16.1 months. We examined changes in tinnitus and accompanying stress and depression in patients after surgery, and examined the hearing changes and the occurrence of complications including hyperacusis...
April 12, 2018: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29495018/localization-and-spatial-discrimination-in-children-and-adolescents-with-moderate-sensorineural-hearing-loss-tested-without-their-hearing-aids
#4
Sylvia Meuret, Alexandra Annemarie Ludwig, Dorothee Predel, Burkhard Staske, Michael Fuchs
The present study investigated two measures of spatial acoustic perception in children and adolescents with sensorineural hearing loss (SNHL) tested without their hearing aids and compared it to age-matched controls. Auditory localization was quantified by means of a sound source identification task and auditory spatial discrimination acuity by measuring minimum audible angles (MAA). Both low- and high-frequency noise bursts were employed in the tests to separately address spatial auditory processing based on interaural time and intensity differences...
March 1, 2018: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29486475/hearing-preservation-with-the-slim-modiolar-electrode-nucleus-ci532%C3%A2-cochlear-implant-a-preliminary-experience
#5
Angel Ramos-Macías, S A Borkoski-Barreiro, J C Falcón-González, A Ramos-de Miguel
As the indications for cochlear implant have expanded to include younger patients and individuals with greater degrees of residual hearing, increasing emphasis has been placed on atraumatic surgery and the preservation of the cochlear structure. Here, a descriptive prospective randomized study was performed. It was shown that residual hearing preservation is possible 12 months postoperatively with an atraumatic perimodiolar flexible electrode array CI532® (Cochlear Ltd, Sydney, Australia). Residual hearing preservation, considered as < 15 dB, was obtained in 70% of the cases...
February 27, 2018: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29462815/a-trend-in-sudden-sensorineural-hearing-loss-data-from-a-population-based-study
#6
Shin Hye Kim, Su-Jong Kim, Hwibin Im, Tae-Hun Kim, Jae-Jun Song, Sung-Won Chae
This is the first study reporting on the incidence and clinical aspects of sudden sensorineural hearing loss (SSNHL) in South Korea. Using Health Insurance Review and Assessment Service data from 2011 to 2015, the monthly incidence of unilateral SSNHL and incidence according to patients' sex, age, and month of diagnosis were investigated. The monthly incidence of unilateral SSNHL increased over the 5-year study period, with a mean annual incidence of 17.76 cases/ 100,000 of the population. The incidence increased with age, with most patients presenting in their 60s...
February 20, 2018: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29393101/resveratrol-promotes-recovery-of-hearing-following-intense-noise-exposure-by-enhancing-cochlear-sirt1-activity
#7
Hao Xiong, Yongkang Ou, Yaodong Xu, Qiuhong Huang, Jiaqi Pang, Lan Lai, Yiqing Zheng
The sirtuin SIRT1 is a highly conserved nicotinamide adenine dinucleotide (NAD)-dependent protein deacetylase known to have protective effects against a wide range of neurological disorders. In the present study, we discovered that C57BL/6 mice fed a long-term diet supplemented with high-dose resveratrol exhibited increased cochlear SIRT1 activity and presented a better recovery of hearing and less loss of hair cells after intense noise exposure compared with those fed a standard chew. Moreover, resveratrol attenuated cochlear SIRT1 decrease and reduced oxidative stress in the cochlea after noise exposure...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29342460/role-of-the-frontal-sinus-in-mediating-ocular-vestibular-evoked-myogenic-potentials-by-bone-vibration-stimuli-applied-to-the-forehead
#8
Kuei-You Lin, Te-Huei Yeh, Fu-Shan Jaw, Yi-Ho Young
This study investigated ocular vestibular-evoked myogenic potential (oVEMP) tests via Fpz and Fz taps to assess the role of the frontal sinus in mediating oVEMP elicitation. Forty healthy subjects and 80 patients with Ménière disease (MD) underwent a series of oVEMP tests via a minishaker tapping at the Fpz and Fz sites in a randomized order. Response rates of oVEMP test via various tapping sites were compared. Dimensions of the frontal sinus were measured via CT scan. A significantly negative correlation between the age and height of the frontal sinus was noted, and the cutoff age for discriminating present and absent Fpz oVEMPs in MD patients was 52 years...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29332068/the-role-of-preoperative-steroids-for-hearing-preservation-cochlear-implantation-results-of-a-randomized-controlled-trial
#9
Jafri Kuthubutheen, Samidha Joglekar, Leah Smith, Lendra Friesen, Kari Smilsky, Tara Millman, Amy Ng, David Shipp, Harvey Coates, Christoph Arnoldner, Julian Nedzelski, Joseph Chen, Vincent Lin
OBJECTIVES: To determine whether preoperative steroids can improve hearing outcomes in cochlear implantation (CI). METHODS: This is a randomized controlled trial involving 30 postlingual deaf CI patients. Subjects had preoperative thresholds of better than or equal to 80 dB at 125 and 250 Hz, and better than or equal to 90 dB at 500 and 1,000 Hz. The subjects were randomized to a control group, an oral steroid group (receiving 1 mg/kg/day of prednisolone for 6 days prior to surgery), or a transtympanic steroid group (receiving a single dose of 0...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29324449/toward-optimizing-vestibular-evoked-myogenic-potentials-normalization-reduces-the-need-for-strong-neck-muscle-contraction
#10
Kimberley S Noij, Barbara S Herrmann, Steven D Rauch, John J Guinan
BACKGROUND: The cervical vestibular evoked myogenic potential (cVEMP) represents an inhibitory reflex of the saccule measured in the ipsilateral sternocleidomastoid muscle (SCM) in response to acoustic or vibrational stimulation. Since the cVEMP is a modulation of SCM electromyographic (EMG) activity, cVEMP amplitude is proportional to muscle EMG amplitude. We sought to evaluate muscle contraction influences on cVEMP peak-to-peak amplitudes (VEMPpp), normalized cVEMP amplitudes (VEMPn), and inhibition depth (VEMPid)...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29298446/effect-of-cochlear-implantation-on-quality-of-life-in-adults-with-unilateral-hearing-loss
#11
Margaret T Dillon, Emily Buss, Meredith A Rooth, English R King, Ellen J Deres, Craig A Buchman, Harold C Pillsbury, Kevin D Brown
OBJECTIVE: Patients with moderate-to-profound sensorineural hearing loss in 1 ear and normal hearing in the contralateral ear, known as unilateral hearing loss (UHL) or single-sided deafness (SSD), may experience improved quality of life with the use of a cochlear implant (CI) in the affected ear. Quality of life assessment before and after implantation may reveal changes to aspects of hearing beyond those explicitly evaluated with behavioral measures. METHODS: The present report completed 2 experiments investigating quality of life outcomes in CI recipients with UHL...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29262414/quality-of-life-and-cost-effectiveness-of-cochlear-implants-a-narrative-review
#12
Matthew G Crowson, Yevgeniy R Semenov, Debara L Tucci, John K Niparko
OBJECTIVES: To review evidence regarding the health-related quality of life (HRQoL) and cost-effectiveness of unilateral and bilateral cochlear implantation (CI) among children and adults with severe-to-profound hearing loss. STUDY DESIGN: Narrative review. METHODS: Publications related to quality of life (QoL) and costs of care in CI were acquired through searches in English-language databases. Studies were included if they had identified the HRQoL attainment, cost of care, cost-utility, or cost-effectiveness associated with CI...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29232662/a-multicenter-clinical-evaluation-of-data-logging-in-cochlear-implant-recipients-using-automated-scene-classification-technologies
#13
Eliana Cristofari, Domenico Cuda, Alessandro Martini, Francesca Forli, Diego Zanetti, Diego Di Lisi, Pasquale Marsella, Daniele Marchioni, Vincenzo Vincenti, Claudia Aimoni, Gaetano Paludetti, Maria Grazia Barezzani, Carlo Antonio Leone, Nicola Quaranta, Marco Bianchedi, Livio Presutti, Antonio Della Volpe, Luca Oscar Redaelli de Zinis, Italo Cantore, Giuseppe Nicolò Frau, Eva Orzan, Francesco Galletti, Silvano Vitale, Ferdinando Raso, Maurizio Negri, Franco Trabalzini, Walter Livi, Lucia Oriella Piccioni, Giampietro Ricci, Paolo Malerba
Currently, there are no studies assessing everyday use of cochlear implant (CI) processors by recipients by means of objective tools. The Nucleus 6 sound processor features a data logging system capable of real-time recording of CI use in different acoustic environments and under various categories of loudness levels. In this study, we report data logged for the different scenes and different loudness levels of 1,366 CI patients, as recorded by SCAN. Monitoring device use in cochlear implant recipients of all ages provides important information about the listening conditions encountered in recipients' daily lives that may support counseling and assist in the further management of their device settings...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29224005/evidence-of-osteoclastic-activity-in-the-human-temporal-bone
#14
Takefumi Kamakura, Joseph B Nadol
Bone remodeling within the otic capsule has been reported to be inhibited especially at or near the cochlea, except under some pathological conditions such as otosclerosis, Paget's disease, or mastoiditis, when bone remodeling can occur. Microcavitations found in periosteal and endosteal layers of human temporal bone specimens without otosclerosis, Paget's disease, or inflammation as reported in the current study are consistent with osteoclastic bone resorption. Thirty-three temporal bones from 33 patients were prepared for light microscopy and classified into 4 groups: histologically proven dehiscence of the superior semicircular canal (SSCD) (n = 3, group 1), age 20 years or younger (n = 10, group 2), age 90 years or older and with otosclerosis (n = 10, group 3), and age 90 years or older without otosclerosis (n = 10, group 4)...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29166635/the-protean-neuropsychiatric-and-vestibuloauditory-manifestations-of-neurosarcoidosis
#15
Jacqueline J Greene, Ilka C Naumann, Janet M Poulik, Kevin T Nella, Lindsay Weberling, Jeffrey P Harris, Akihiro J Matsuoka
BACKGROUND: A rare subset of sarcoidosis, neurosarcoidosis, is reported to occur in 5-7% of sarcoid patients and can manifest in a variety of ways. The most common are facial paralysis and optic neuritis, less commonly causing cochleovestibulopathy, blindness, anosmia, and other cranial nerve (CN) palsies. The sensory deficit may be severe and psychiatric symptoms may result from the effects of the disease or steroid treatment. Although MRI-compatible cochlear implants are now available, concerns about the feasibility of recoverable hearing with cochlear implantation in these patients as well as the practical difficulty of disease monitoring due to implant artifact must be considered...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29130955/tinnitus-and-hearing-survey-a-polish-study-of-validity-and-reliability-in-a-clinical-population
#16
Danuta Raj-Koziak, Elzbieta Gos, Joanna Rajchel, Adam Piłka, Henryk Skarżyński, Joanna Rostkowska, Piotr H Skarzynski
This study investigates the psychometric properties of the Polish version of the Tinnitus and Hearing Survey (THS-POL), which is a tool for evaluating what proportion of patients' tinnitus is due to hearing problems and what proportion is specifically due to the tinnitus. The THS-POL was created using the translation-backtranslation method. Study participants completed the THS-POL twice over a period of 3 days. The test-retest analysis shows excellent strength of correlations (THS-POL subscale A r = 0.89, subscale B r = 0...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29084395/electrophysiological-evidence-of-the-basilar-membrane-travelling-wave-and-frequency-place-coding-of-sound-in-cochlear-implant-recipients
#17
Luke Campbell, Christofer Bester, Claire Iseli, David Sly, Adrian Dragovic, Anthony W Gummer, Stephen O'Leary
AIM: To obtain direct evidence for the cochlear travelling wave in humans by performing electrocochleography from within the cochlea in subjects implanted with an auditory prosthesis. BACKGROUND: Sound induces a travelling wave that propagates along the basilar membrane, exhibiting cochleotopic tuning with a frequency-dependent phase delay. To date, evoked potentials and psychophysical experiments have supported the presence of the travelling wave in humans, but direct measurements have not been made...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29080887/evaluation-of-vestibular-functions-in-patients-with-vogt-koyanagi-harada-disease
#18
Keishi Fujiwara, Shinya Morita, Kimiko Hoshino, Atsushi Fukuda, Yuji Nakamaru, Akihiro Homma
Vogt-Koyanagi-Harada (VKH) disease is an idiopathic, multisystem autoimmune disorder characterized by bilateral, diffuse granulomatous uveitis associated with neurological, audiovestibular, and dermatological manifestations. The purpose of this study is to investigate vestibular functions in patients with VKH disease. A total of 43 patients with VKH disease in Hokkaido University Hospital were enrolled in this study. Subjective symptoms such as dizziness or vertigo and the results of various vestibular examinations including nystagmus testing, caloric testing, and vestibular-evoked myogenic potential (VEMP) testing were investigated...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29059669/clinical-investigation-of-the-nucleus-slim-modiolar-electrode
#19
Antje Aschendorff, Robert Briggs, Goetz Brademann, Silke Helbig, Joachim Hornung, Thomas Lenarz, Mathieu Marx, Angel Ramos, Timo Stöver, Bernard Escudé, Chris J James
AIMS: The Nucleus CI532 cochlear implant incorporates a new precurved electrode array, i.e., the Slim Modiolar electrode (SME), which is designed to bring electrode contacts close to the medial wall of the cochlea while avoiding trauma due to scalar dislocation or contact with the lateral wall during insertion. The primary aim of this prospective study was to determine the final position of the electrode array in clinical cases as evaluated using flat-panel volume computed tomography...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29049998/endoplasmic-reticulum-stress-is-involved-in-cochlear-cell-apoptosis-in-a-cisplatin-induced-ototoxicity-rat-model
#20
Shimin Zong, Tianyi Liu, Fangmin Wan, Pei Chen, Pan Luo, Hongjun Xiao
Endoplasmic reticulum (ER) stress arises when excessive improperly folded proteins accumulate in the ER lumen. When ER stress occurs, the unfolded protein response (UPR) is subsequently activated to restore ER proteostasis. However, severe ER stress leads to apoptosis. Recent studies have suggested that cisplatin cytotoxicity may be related to ER stress. The purpose of this study was to determine whether ER stress participates in cochlear cell apoptosis in a cisplatin-induced ototoxicity rat model and to also determine the possible relationship between ER stress and hearing loss...
2017: Audiology & Neuro-otology
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