journal
MENU ▼
Read by QxMD icon Read
search

Helicobacter

journal
https://www.readbyqxmd.com/read/28425141/efficacy-of-helicobacter-pylori-eradication-therapies-in-korea-a-systematic-review-and-network-meta-analysis
#1
REVIEW
Yoon Suk Jung, Chan Hyuk Park, Jung Ho Park, Eunwoo Nam, Hang Lak Lee
BACKGROUND: The efficacy of Helicobacter pylori eradication regimens may depend on the country where the studies were performed because of the difference in antibiotic resistance. We aimed to analyze the efficacy of H. pylori eradication regimens in Korea where clarithromycin resistance rate is high. METHODS: We searched for all relevant randomized controlled trials published until November 2016 that investigated the efficacy of H. pylori eradication therapies in Korea...
April 19, 2017: Helicobacter
https://www.readbyqxmd.com/read/28402048/sensitivity-of-helicobacter-pylori-detection-by-giemsa-staining-is-poor-in-comparison-with-immunohistochemistry-and-fluorescent-in-situ-hybridization-and-strongly-depends-on-inflammatory-activity
#2
Éva Kocsmár, Ildikó Szirtes, Zsófia Kramer, Attila Szijártó, László Bene, György Miklós Buzás, István Kenessey, Peter Bronsert, Agnes Csanadi, Lisa Lutz, Martin Werner, Ulrich Friedrich Wellner, András Kiss, Zsuzsa Schaff, Gábor Lotz
BACKGROUND: Conventional stainings (including H&E and special stains like Giemsa) are the most widely applied histopathologic detection methods of Helicobacter pylori (HP). MATERIALS AND METHODS: We aimed to compare the diagnostic performance of Giemsa staining with immunohistochemistry (IHC) and fluorescent in situ hybridization (FISH) on a monocentric cohort of 2896 gastric biopsies and relate results to histologic alterations in order to find such histopathologic subgroups in which these methods underperform...
April 12, 2017: Helicobacter
https://www.readbyqxmd.com/read/28402047/survival-of-helicobacter-pylori-in-gastric-acidic-territory
#3
REVIEW
Shamshul Ansari, Yoshio Yamaoka
BACKGROUND: Helicobacter pylori is well adapted to colonize the epithelial surface of the human gastric mucosa and can cause persistent infections. In order to infect the gastric mucosa, it has to survive in the gastric acidic pH. This organism has well developed mechanisms to neutralize the effects of acidic pH. OBJECTIVE: This review article was designed to summarize the various functional and molecular aspects by which the bacterium can combat and survive the gastric acidic pH in order to establish the persistent infections...
April 12, 2017: Helicobacter
https://www.readbyqxmd.com/read/28402041/inactivation-of-ferric-uptake-regulator-fur-attenuates-helicobacter-pylori-j99-motility-by-disturbing-the-flagellar-motor-switch-and-autoinducer-2-production
#4
Ai-Yun Lee, Cheng-Yen Kao, Yao-Kuan Wang, Ssu-Yuan Lin, Tze-Ying Lai, Bor-Shyang Sheu, Chien-Jung Lo, Jiunn-Jong Wu
BACKGROUND: Flagellar motility of Helicobacter pylori has been shown to be important for the bacteria to establish initial colonization. The ferric uptake regulator (Fur) is a global regulator that has been identified in H. pylori which is involved in the processes of iron uptake and establishing colonization. However, the role of Fur in H. pylori motility is still unclear. MATERIALS AND METHODS: Motility of the wild-type, fur mutant, and fur revertant J99 were determined by a soft-agar motility assay and direct video observation...
April 12, 2017: Helicobacter
https://www.readbyqxmd.com/read/28326664/the-corpus-predominant-gastritis-index-can-be-an-early-and-reversible-marker-to-identify-the-gastric-cancer-risk-of-helicobacter-pylori-infected-nonulcer-dyspepsia
#5
Hsiu-Chi Cheng, Yu-Ching Tsai, Hsiao-Bai Yang, Yi-Chun Yeh, Wei-Lun Chang, Hsin-Yu Kuo, Cheng-Chan Lu, Bor-Shyang Sheu
BACKGROUND: Corpus-predominant gastritis index (CGI) is an early histological marker to identify Helicobacter pylori-infected gastric cancer relatives at risk of cancer. This study validated whether CGI is more prevalent in H. pylori-infected nonulcer dyspepsia (NUD) subjects than in duodenal ulcer (DU) controls and whether it is reversible after H. pylori eradication or is correlated with noninvasive biomarkers. MATERIALS AND METHODS: In this longitudinal cohort study, 573 H...
March 22, 2017: Helicobacter
https://www.readbyqxmd.com/read/28303625/eradication-rate-of-helicobacter-pylori-infection-is-directly-influenced-by-adherence-to-therapy-in-children
#6
Kallirroi Kotilea, Joyce Mekhael, Assaad Salame, Tania Mahler, Veronique Yvette Miendje-Deyi, Samy Cadranel, Patrick Bontems
BACKGROUND: Current commonly accepted strategies to eradicate Helicobacter pylori in children are a 10-day sequential treatment or a triple therapy for 7-14 days. To avoid further expensive and possibly risky investigations as well as induction of secondary antimicrobial resistance, a success rate of elimination strategies over 90% in a per-protocol analysis is the target goal but rates observed in clinical trials are lower. Antimicrobial resistance is a well-recognized risk factor for treatment failure; therefore, only a treatment tailored to susceptibility testing should be recommended...
March 17, 2017: Helicobacter
https://www.readbyqxmd.com/read/28299869/helicobacter-pylori-infection-is-associated-with-reduced-prevalence-of-colonic-diverticular-disease
#7
Lars Erik Bartels, Peter Jepsen, Anders Tøttrup, Hendrik Vilstrup, Jens Frederik Dahlerup
BACKGROUND: Colonic diverticular disease is a common disorder with increasing incidence in Western societies. The intestinal microbiome may be among etiological factors. Helicobacter pylori may protect against some intestinal diseases, and incidence of H. pylori is decreasing in Western societies. Thus, we aimed to determine whether H. pylori is associated to decreased prevalence of registered colonic diverticular disease. MATERIALS AND METHODS: In a historical cohort study, patients were enrolled from primary health care centers after urea breath test for H...
March 16, 2017: Helicobacter
https://www.readbyqxmd.com/read/28271597/population-genetic-structure-of-helicobacter-pylori-strains-from-portuguese-speaking-countries
#8
Mónica Oleastro, Raquel Rocha, Filipa F Vale
BACKGROUND: The human gastric colonizer Helicobacter pylori is useful to track human migrations given the agreement between the bacterium phylogeographic distribution and human migrations. As Portugal was an African and Brazilian colonizer for over 400 years, we hypothesized that Portuguese isolates were likely genetically closer with those from countries colonized by Portuguese in the past. We aimed to characterize the population structure of several Portuguese-speaking countries, including Portugal, Brazil, Angola, and Cape Verde...
March 8, 2017: Helicobacter
https://www.readbyqxmd.com/read/28244264/real-world-practice-and-expectation-of-asia-pacific-physicians-and-patients-in-helicobacter-pylori-eradication-reap-hp-survey
#9
Yoen-Young Chuah, Deng-Chyang Wu, Seng-Kee Chuah, Jyh-Chin Yang, Tzong-Hsi Lee, Hong-Zen Yeh, Chan-Lin Chen, Yu-Hwa Liu, Ping-I Hsu
OBJECTIVE: The aims of the study were: 1, to survey the most popular anti-H. pylori regimens in Asia-Pacific region and the real-world effectiveness of these regimens; and 2, to investigate the expectation gaps of eradication rate between physicians and patients. DESIGN: A questionnaire was distributed to Asia-Pacific physicians who attended the Asia-Pacific Digestive Week 2015 meeting. Reported eradication rates from the literatures were compared with real-world rates of surveyed popular regimens within the region...
February 28, 2017: Helicobacter
https://www.readbyqxmd.com/read/28244177/the-histone-like-protein-hu-has-a-role-in-gene-expression-during-the-acid-adaptation-response-in-helicobacter-pylori
#10
Alhejandra Álvarez, Héctor Toledo
BACKGROUND: Gastritis, ulcers, and gastric malignancy have been linked to human gastric epithelial colonization by Helicobacter pylori. Characterization of the mechanisms by which H. pylori adapts to the human stomach environment is of crucial importance to understand H. pylori pathogenesis. MATERIAL AND METHODS: In an effort to extend our knowledge of these mechanisms, we used proteomic analysis and qRT-PCR to characterize the role of the histone-like protein HU in the response of H...
February 28, 2017: Helicobacter
https://www.readbyqxmd.com/read/28181350/no-evidence-of-a-role-for-mitochondrial-complex-i-in-helicobacter-pylori-pathogenesis
#11
Garrett Z Ng, Bi-Xia Ke, Adrienne Laskowski, David R Thorburn, Philip Sutton
BACKGROUND: Complex I is the first enzyme complex in the mitochondrial respiratory chain, responsible for generating a large fraction of energy during oxidative phosphorylation. Recently, it has been identified that complex I deficiency can result in increased inflammation due to the generation of reactive oxygen species by innate immune cells. As a reduction in complex I activity has been demonstrated in human stomachs with atrophic gastritis, we investigated whether complex I deficiency could influence Helicobacter pylori pathogenesis...
February 9, 2017: Helicobacter
https://www.readbyqxmd.com/read/28125857/new-bismuth-containing-quadruple-therapy-in-patients-infected-with-helicobacter-pylori-a-first-italian-experience-in-clinical-practice
#12
Antonio Tursi, Francesco Di Mario, Marilisa Franceschi, Rudi De Bastiani, Walter Elisei, Gianluca Baldassarre, Antonio Ferronato, Simone Grillo, Stefano Landi, Maria Zamparella, Manuela De Polo, Laura Boscariolo, Marcello Picchio
BACKGROUND: Rising antibiotic resistance requires the evaluation of new and effective therapies. AIMS: To test the efficacy and safety of the new bismuth-containing quadruple therapy in patients infected with Helicobacter pylori. MATERIAL AND METHODS: Consecutive H. pylori-positive dyspeptic patients were enrolled, either naïve or with previous failure treatment. Patients were treated with Pylera(®) (three-in-one capsules containing bismuth subcitrate potassium 140 mg, metronidazole 125 mg, and tetracycline 125 mg) three capsules q...
January 26, 2017: Helicobacter
https://www.readbyqxmd.com/read/28124492/helicobacter-pylori-infection-is-an-independent-risk-factor-of-early-and-advanced-colorectal-neoplasm
#13
Tae Jun Kim, Eun Ran Kim, Dong Kyung Chang, Young-Ho Kim, Sun-Young Baek, Kyunga Kim, Sung Noh Hong
BACKGROUND: The role of Helicobacter pylori (H. pylori) in the development of colorectal neoplasm remains controversial. We examined the association between H. pylori infection and colorectal neoplasm in a large sample of healthy participants who underwent screening colonoscopy. METHODS: A cross-sectional study of 8916 men, who participated in a regular health-screening examination that included an H. pylori-specific immunoglobulin G antibody test and colonoscopy, was conducted to evaluate the association between H...
January 26, 2017: Helicobacter
https://www.readbyqxmd.com/read/28124467/species-specific-immunity-to-helicobacter-suis
#14
Iris Bosschem, Bram Flahou, Kim Van Deun, Stefaan De Koker, Jiri Volf, Annemieke Smet, Richard Ducatelle, Bert Devriendt, Freddy Haesebrouck
BACKGROUND: Helicobacter (H.) suis is mainly associated with pigs, but is also the most prevalent gastric non-H. pylori Helicobacter species found in humans. Both H. pylori and H. suis may cause persistent infection of the stomach. Several immune evasion mechanisms have been proposed for H. pylori, which focus to a great extent on its major virulence factors, which are absent in H. suis. The aim of this study was to gain more knowledge on immune evasion by H. suis. MATERIALS AND METHODS: Cytokine expression kinetics were monitored in the stomach of BALB/c mice experimentally infected with H...
January 26, 2017: Helicobacter
https://www.readbyqxmd.com/read/28297163/helicobacter-pylori-infection-in-omani-children
#15
Siham Al-Sinani, Sharef Waadallah Al-Mulaabed, Khalid Al-Naamani, Hyatt Al-Sharji
No abstract text is available yet for this article.
April 2017: Helicobacter
https://www.readbyqxmd.com/read/27933701/ccr2-mediates-helicobacter-pylori-induced-immune-tolerance-and-contributes-to-mucosal-homeostasis
#16
Xia Sun, Min Zhang, Mohamad El-Zaatari, Gray B Huffnagle, John Y Kao
BACKGROUND: We previously demonstrated that H. pylori infection leads to increased induction of regulatory T cells in local and systemic immune compartments. Here, we investigate the role of CCR2 in the tolerogenic programing of dendritic cells in a mouse model of H. pylori infection. MATERIALS AND METHODS: CCR2 deficient (CCR2KO) mice and wild-type (Wt) mice infected with H. pylori SS1 strain were analyzed by qPCR and FACS analysis. In vitro, bone marrow-derived DC on day 6 from CCR2KO and Wt mice cocultured with or without H...
April 2017: Helicobacter
https://www.readbyqxmd.com/read/27879042/high-antibiotic-resistance-of-helicobacter-pylori-and-its-effect-on-tailored-and-empiric-eradication-of-the-organism-in-lower-silesia-poland
#17
Stanisław Ferenc, Jan Gnus, Magdalena Kościelna, Małgorzata Kinda, Andriy Yarka, Luke Stewart, Wojciech Witkiewicz
BACKGROUND: At present, the resistance to antibiotics is considered the most important reason for Helicobacter pylori (HP) eradication failure. The aim of this study was to estimate the prevalence of antimicrobial resistance of HP strains and to evaluate tailored and empiric therapeutic regimens in patients with peptic ulcer disease associated with infection of this microorganism. MATERIALS AND METHODS: Between May 2011 and February 2013, 185 consecutive Polish patients with at least one positive Helicobacter pylori test (urease test, histopathologic examination, and/or culture) underwent eradication therapy...
April 2017: Helicobacter
https://www.readbyqxmd.com/read/27786400/helicobacter-pylori-colonization-and-pregnancies-complicated-by-preeclampsia-spontaneous-prematurity-and-small-for-gestational-age-birth
#18
Wouter J den Hollander, Sarah Schalekamp-Timmermans, I Lisanne Holster, Vincent W Jaddoe, Albert Hofman, Henriëtte A Moll, Guillermo I Perez-Perez, Martin J Blaser, Eric A P Steegers, Ernst J Kuipers
BACKGROUND: Preeclampsia (PE), small for gestational age (SGA), and spontaneous preterm birth (PTB) each may be complications of impaired placental function in pregnancy. Although their exact pathogenesis is still unknown, certain infectious agents seem to play a role. Helicobacter pylori (H. pylori) colonization has been associated with increased risk for PE. Our aim was to assess the association between H. pylori colonization and PE, SGA, and PTB. MATERIAL AND METHODS: We measured IgG anti-H...
April 2017: Helicobacter
https://www.readbyqxmd.com/read/27785853/helicobacter-pylori-infection-and-its-related-factors-in-junior-high-school-students-in-nagano-prefecture-japan
#19
Yoshiko Nakayama, Yingsong Lin, Minoru Hongo, Hiroya Hidaka, Shogo Kikuchi
BACKGROUND: There have been few reports on Helicobacter pylori (H. pylori) infection in asymptomatic Japanese children and adolescents. We hypothesized that the prevalence of H. pylori infection is very low among Japanese children and that clinical variables such as serum pepsinogen and iron levels are associated with H. pylori infection. MATERIALS AND METHODS: We conducted a cross-sectional analysis of a sample of 454 junior high school students aged 12-15 years in four areas in Nagano Prefecture...
April 2017: Helicobacter
https://www.readbyqxmd.com/read/27717096/prevalence-of-helicobacter-pylori-infection-in-newly-arrived-refugees-attending-the-migrant-health-service-south-australia
#20
Nur R Abdul Rahim, Jill Benson, Kathryn Grocke, Deeva Vather, Jessica Zimmerman, Tessa Moody, Lillian Mwanri
BACKGROUND: To determine the prevalence of Helicobacter pylori infection in the refugee population attending the Migrant Health Service, South Australia, identify demographic factors associated with infection and compare prevalence of infection in refugees with that of the nonrefugee population in Australia. MATERIALS AND METHODS: Cross-sectional study conducted between October 2010 and August 2013. Monoclonal stool antigen testing for H. pylori infection is performed as part of a comprehensive health assessment for newly arrived refugees...
April 2017: Helicobacter
journal
journal
32491
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"