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Allergy and Asthma Proceedings:

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https://www.readbyqxmd.com/read/28710850/efficacy-and-safety-of-beclomethasone-dipropionate-breath-actuated-or-metered-dose-inhaler-in-pediatric-patients-with-asthma
#1
M Vandewalker, L Hickey, C J Small
BACKGROUND: Breath-actuated inhalers (BAI) eliminate the need for hand-breath coordination and, therefore, simplify thedelivery of inhaled medication. OBJECTIVE: To evaluate the efficacy and safety of beclomethasone dipropionate BAI and metered-dose inhaler (MDI) versus placebo in pediatric patients ages 4-11 years with persistent asthma. METHODS: In this double-blind, double-dummy, phase III study, 628 children with persistent asthma were randomly assigned(1:1:1:1:1) to twice-daily beclomethasone dipropionate (BAI 80 micrograms/day, BAI 160 micrograms/day, MDI 80 micrograms/day, or MDI 160 micrograms/day) or to placebo...
July 14, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28639542/fluticasone-propionate-and-fluticasone-propionate-salmeterol-multidose-dry-powder-inhalers-compared-with-placebo-for-persistent-asthma
#2
L D Sher, G Yiu, A Sakov, S Liu, C F Caracta
BACKGROUND: A novel, inhalation-driven, multidose dry powder inhaler (MDPI) has been developed, which allows for lowerdoses of fluticasone propionate (Fp) and Fp/salmeterol (FS) for the treatment of patients with asthma. OBJECTIVE: This phase III, multicenter, double-blind, parallel-group study (NCT02141854) evaluated the efficacy and safetyof Fp MDPI and FS MDPI versus placebo MDPI. METHODS: Patients aged greater than or equal to 12 years with persistent asthma who previously took an inhaled corticosteroid with or without a long-acting beta-agonist entered a 14- to 21-day run-in period, during which they received single-blind, low-dose Fp MDPI 50 microgram (1 inhalation twice daily [b...
June 21, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28540844/a-6-month-safety-and-efficacy-study-of-fluticasone-propionate-and-fluticasone-propionate-salmeterol-multidose-dry-powder-inhalers-in-persistent-asthma
#3
Lyndon Mansfield, Gloria Yiu, Anat Sakov, Siyu Liu, Cynthia Caracta
BACKGROUND: A novel multidose dry powder inhaler (MDPI) that is breath actuated, easy, and intuitive to use has been developed for administering fluticasone propionate (Fp) and Fp/salmeterol (FS). OBJECTIVE: To assess the safety and efficacy of Fp MDPI versus Fp hydrofluoroalkane (HFA) and FS MDPI versus FS dry-powder inhaler (DPI). METHODS: This phase III, 26-week, open-label, active drug-controlled study enrolled subjects ≥12 years old with persistent asthma...
July 24, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28668115/abstracts-from-the-new-england-society-of-allergy-spring-meeting-april-7-2017-westford-ma
#4
(no author information available yet)
No abstract text is available yet for this article.
July 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28668114/for-the-patient-prevalence-and-triggers-of-anaphylactic-events-in-schools
#5
(no author information available yet)
No abstract text is available yet for this article.
July 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28668113/a-28-year-old-woman-with-fever-rash-and-pancytopenia
#6
Sebastian Ochoa, Kyle Cheng, Christine M Fleury, Stefano Luccioli, Joseph A Bellanti
A 28-year-old Hispanic woman was admitted to the hospital with fever, sore throat, arthralgia, and a generalized rash of 2 weeks' duration. Her medical history was significant for various food and medication allergies. Multiple antibiotics were given for suspected infection, and she subsequently developed a new skin rash, acute liver injury, eosinophilia, and pancytopenia. Additional studies showed hypertriglyceridemia; elevated interleukin-2 receptor levels; absent natural killer cell activity; and hemophagocytosis in skin, liver, and bone marrow biopsy specimens...
July 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28668112/pearls-and-pitfalls-autoimmune-lymphoproliferative-syndrome-and-autoimmune-lymphoproliferative-syndrome-like-disease
#7
Anne K Bartels, Taylor A Banks, Jeannie L Bay
A case of autoimmune lymphoproliferative syndrome (ALPS) was presented, followed by a discussion of the clinical characteristics, pathophysiology, diagnosis, and management of this disease. Clinical pearls and pitfalls are emphasized for the use of the practicing allergist and the fellow in-training. The diagnosis of ALPS was guided by published criteria. A careful history and workup were needed to exclude other possible etiologies for the patient's symptoms and physical findings. ALPS often carries significant morbidity and is best managed through a multidisciplinary approach...
July 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28668111/a-10-year-experience-of-a-novel-and-safe-modified-environmental-rush-immunotherapy-protocol
#8
Merritt L Fajt, Stacy L Rosenberg, Emmanuelle Yecies, Russell S Traister, Andrej A Petrov
BACKGROUND: Allergen immunotherapy (AIT) is an effective treatment option for allergic rhinitis. Although conventional AIT takes 6 months to reach maintenance dosing, rush AIT accelerates the build-up period and reaches the maintenance dose months earlier. However, accelerated schedules of AIT carry an increased risk of systemic reactions (SR). OBJECTIVE: We aimed to describe a novel 1-day, eight-step modified environmental rush immunotherapy (MERIT) protocol, characteristics of the patients who underwent this therapy, and the safety of this procedure...
July 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28668110/association-of-maternal-depression-and-allergic-diseases-in-korean-children
#9
Cheol Hong Kim, Sung Hoon Kim, Ju Suk Lee
PURPOSE: An association between childhood allergic disease and parental psychological disorders has been reported. However, little is known about the relationship between childhood allergic disease and maternal depression. This study was performed to determine if there is an association between childhood allergic disease and maternal depression. METHODS: Data were acquired from 13,782 subjects (8091 mothers) ages < 18 years who participated in the Korea National Health and Nutrition Examination Surveys, which was conducted from 2007 to 2014...
July 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28668109/seasonal-variation-and-monthly-patterns-of-skin-symptoms-in-korean-children-with-atopic-eczema-dermatitis-syndrome
#10
Minji Kim, Young-Min Kim, Ji Young Lee, Hea-Kyoung Yang, Hyunmi Kim, Joongbum Cho, Kangmo Ahn, Jihyun Kim
BACKGROUND: There have been controversies about the seasonality in aggravation of atopic eczema/dermatitis syndrome (AEDS) symptoms, although understanding the seasonal patterns of AEDS symptoms is an important step in preventing exacerbation through proactive management. OBJECTIVE: The aim of this study was to evaluate whether there are seasonal variations or monthly patterns of symptoms in children with AEDS. METHODS: A total of 590 children with AEDS (median age, 21 months) were enrolled and were followed up for at least 1 year between August 2012 and March 2015...
July 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28668108/prevalence-and-triggers-of-anaphylactic-events-in-schools
#11
Martha V White, Suyapa Silvia, Rafael Muniz, Christopher Herrem, Susan L Hogue
BACKGROUND: Prevention and management of anaphylaxis in schools is an area of active interest as allergy and asthma rates in children continue to increase. A greater understanding of the prevalence and characteristics of anaphylaxis can help guide preventive and management strategies both within and outside of the school setting, with the goal of reducing morbidity and mortality. OBJECTIVE: This study was performed to elucidate the epidemiology of and management strategies for anaphylaxis in the school setting...
July 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28668107/asthma-in-older-people-hospitalized-with-influenza-in-spain-a-case-control-study
#12
María Morales-Suárez-Varela, Agustín Llopis-González, Carlos Vergara-Hernández, Estrella Fernandez-Fabrellas, Francisco Sanz, María José Perez-Lozano, Vicente Martin, Jenaro Astray, Jesús Castilla, Mikel Egurrola, Luis Force, Diana Toledo, Àngela Domínguez
BACKGROUND: Influenza infection is an exacerbating factor for asthma, and its prevention is critical in older patients with asthma. OBJECTIVE: This study investigated the association between asthma and influenza-related hospitalization, in Spain, of patients ages ≥ 65 years and their clinical evolution. METHODS: A multicenter case-control study was carried out in 20 Spanish hospitals during the 2013-2014 and 2014-2015 influenza seasons. Patients ages ≥ 65 years hospitalized with laboratory-confirmed influenza with and without asthma were matched with controls according to the presence of asthma, sex, age, hospital, and date of hospitalization...
July 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28668106/atopic-dermatitis-treatment-current-state-of-the-art-and-emerging-therapies
#13
Jonathan I Silverberg
BACKGROUND: Atopic dermatitis (AD) can be debilitating and often requires the use of combination topical and systemic therapy to achieve adequate disease control. METHODS: A non-systematic review was performed of current state of the art and emerging therapies for AD. RESULTS: There are a number of topical agents approved by the U.S. Food and Drug Administration (FDA) for the treatment of AD and multiple nonapproved systemic agents that are used off label for the treatment of AD...
July 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28668105/the-atopic-disorders-and-atopy-%C3%A2-strange-diseases-now-better-defined
#14
Joseph A Bellanti, Russell A Settipane
No abstract text is available yet for this article.
July 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28668104/a-call-to-arms-of-specialty-societies-to-review-the-who-international-classification-of-diseases-eleventh-revision-terms-appropriate-for-the-diseases-they-manage-the-example-of-the-joint-allergy-academies
#15
Luciana K Tanno, Thomas Casale, Nikolaos G Papadopoulos, Mario Sanchez-Borges, Francis Thiens, Ruby Pawankar, Moises A Calderon, Maximiliano Gómez, Juan C Sisul, Ignacio J Ansotegui, James Sublett, Pascal Demoly
No abstract text is available yet for this article.
July 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28631599/efficacy-and-safety-of-omalizumab-in-children-and-adolescents-with-moderate-to-severe-asthma-a-systematic-literature-review
#16
Jonathan Corren, Abhishek Kavati, Benjamin Ortiz, Jennifer A Colby, Kimberly Ruiz, Brett A Maiese, Sarah M Cadarette, Reynold A Panettieri
BACKGROUND: There are limited pediatric data about the use of omalizumab, especially the effectiveness and safety of omalizumab in the real-world management of allergic asthma. OBJECTIVE: The objective of this study was to summarize the safety and efficacy of omalizumab in both randomized clinical trials (RCT) used for U.S. Food and Drug Administration registration and real-world studies (RWS) based on clinical care of children with moderate-to-severe asthma. METHODS: Studies that evaluated omalizumab use in patients <18 years old and with asthma, published between January 2003 and October 2016, were retrieved from medical literature data bases...
July 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28442001/asthma-control-in-saudi-arabia-gender-implications
#17
A A Torchyan
No abstract text is available yet for this article.
May 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28442000/association-between-depression-and-asthma-in-korean-adults
#18
S Choi, S H Kim, J S Lee
No abstract text is available yet for this article.
May 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28441999/vitamin-d-and-food-allergies-in-children-a-systematic-review-and-meta-analysis
#19
E K Willits, Z Wang, J Jin, B Patel, M Motosue, A Bhagia, J Almasri, P J Erwin, S Kumar, A Y Joshi
No abstract text is available yet for this article.
May 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28441998/25-hydroxyvitamin-d-biomarkers-of-eosinophilic-inflammation-and-airway-remodeling-in-children-with-newly-diagnosed-untreated-asthma
#20
G Sypniewska, M Krintus, G Fulgheri, J Siodmiak, M Kuligowska-Prusinska, B Stepien-Jaszowska, R Staszak-Kowalska, A Zawadzka-Krajewska, S Kierat, K Bergmann, U Demkow
No abstract text is available yet for this article.
May 1, 2017: Allergy and Asthma Proceedings:
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