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Mymensingh Medical Journal: MMJ

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https://www.readbyqxmd.com/read/30487515/off-label-medication-in-children-responsibilities-of-pediatrician-and-neonatologist
#1
J C Das, M A Hossain, M Shahidullah, M A Mannan
Use of drug in pediatrics and neonatology should be rational. There are clinical situations when the use of unlicensed medicines or use of medicines outside the terms of license (i.e., 'off-label') may be judged by prescriber in the best interest of the patient. Off-label prescribing is clinically appropriate when the benefits outweigh the potential risks. Such practice is particularly common in pediatrics and neonatology where development of age-appropriate formulations is difficult. Before going to prescribe a drug on off-label basis, the clinician should be satisfied that an alternative medicine would not meet the patient's needs...
October 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/30487514/role-of-immune-cells-and-cytokines-for-immune-response-in-kala-azar
#2
S R Sarkar, N C Ray, S Nahar, S Roy, M A Aziz, A M Al Amin, S K Paul
Resolution of leishmanial infection is dependent on the coordinated interactions between components of cell mediated immune response, central to which is the activation of targeted T-cell populations for appropriate cytokine production and activation of infected cells. There is a correlation between the clinical outcome of Leishmania infection and the cytokine response profile. While a protective immune response against Leishmania has been clearly identified to be related to the influence of a type-l response and IFN-γ production, the precise role of T helper (TH) 2 cytokines in non-healing infections requires further exploration...
October 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/30487513/septicemia-meningitis-and-bilateral-subdural-empyema-in-an-infant-caused-by-staphylococcus-aureus
#3
S Ahmed, T Biswas, S P Paul
Staphylococcus aureus is a global bacterial pathogen. It is an uncommon pathogen causing central nervous system infections, accounting for <1% cases of bacterial meningitis. Sinusitis, trauma and presence of an intracranial device have been reported as risk factors for developing meningitis and brain abscesses. A previously healthy 5-month-old female infant presented to a hospital in North-Eastern India in February 2018 with Staphylococcus aureus sepsis and meningitis and was subsequently detected to have developed bilateral subdural empyema on computed tomography scan of the brain...
October 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/30487512/a-case-of-single-atrium-mitral-valve-prolapse-spontaneously-closed-inlet-vsd-with-polydactyly
#4
R K Majumder, T Haque
Single Atrium is a complex cardiac anomaly and generally a component of certain congenital syndromes. It is extremely rare for SA to be observed as an isolated defect. We report here a 14 year-old male patient with SA with MVP with spontaneously-closed inlet-VSD with polydactyly. He was examined first at "L. Harun Health Complex" 77 Sehora, Mymensingh, Bangladesh on 11th September 2016 and then at National Heart Foundation Hospital, Mirpur, Dhaka, Bangladesh on 17th October 2016.
October 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/30487511/primary-non-hodgkin-lymphoma-of-sphenoid-sinus-involving-cavernus-sinus-and-clivus-with-isolated-3rd-nerve-palsy
#5
D Chowdhury, A Rahman, M H Rashid, B Chaurasia, M Kamal, K K Barua
Lymphomas are group of malignant neoplasm having origins from lymphoreticular cells. B cell Non Hodgkin Lymphoma (BNHL) of sphenoid sinus as primary site for lymphomas are very rare and whenever involves comes usually with ocular manifestations. The proximity of the lesion to optic nerve and cavernous sinus present a high risk of developing unilateral ophthalmoplegia or even blindness. The vast majority of cases of localized sphenoid sinus lymphomas are usually curable to surgery, chemotherapy alone or combination of both, sometimes radiotherapy...
October 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/30487510/anti-phospholipid-antibody-syndrome-presenting-as-huge-ascites-a-case-report
#6
A H Khan, M M Rahman, M F Rahaman, M Rahman, M K Mondal, M A Chowdhury
Antiphospholipid Syndrome (APS) is characterized by arterial, venous or small vessel thromboses and/or pregnancy morbidity in the presence of persistently elevated titers of antiphospholipid antibodies. Since virtually any organ can be involved, the clinical presentation of APS is very varied. Abdominal manifestations are rare but may be life-threatening, and include Budd-Chiari Syndrome. We report the case of a 26-year-old woman with primary APS, on aspirin treatment, who presented to us at Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh in March 2017 with ascites for which she had been receiving treatment for abdominal tuberculosis...
October 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/30487509/extra-skeletal-ewing-s-sarcoma-involving-perineum-of-a-young-male-patient
#7
M A Habib, M A Taher, S N Sumi, K Nahar, T A Khan, G M Mia, M S Islam, B P Dey
Ewing's Sarcoma is the second most common primary malignant bone tumor in children and young adults after osteosarcoma but exceptionally it can arise from extra skeletal sites also. Extra skeletal Ewing's sarcoma is of neuroectodermal origin and usually involves extremities, retroperitoneum and paravertebral regions. No case of extra skeletal Ewing's sarcoma involving perineum is yet reported. A 16 years old male patient admitted to colorectal surgery department of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh in July 2015 having swellings in perineum as well as both inguinal regions...
October 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/30487508/situs-inversus-totalis-laparoscopic-cholecystectomy-and-some-modifications
#8
M K Khan, R H Talukder
Laparoscopic cholecystectomy has become the standard approach since its introduction in 1987 by Mouret. Situs inversus totalis is a rare anomaly in which transposition of the organ to the opposite site of the body occurs. Laparoscopic cholecystectomy due to gall stone disease in such few cases has been reported in the literature. The presentation of the cholecystitis, its diagnosis and the operative procedure can pose problems. Laparoscopic cholecystectomy in those patients is technically more demanding and needs reorientation of visual motor skill to left upper quadrant...
October 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/30487507/hepatic-hydatid-cyst-a-case-report
#9
F A Dowel, R Ara, N Nahar, N Khan, S Z Rima, R K Chakraborty, M Nadiruzzaman
Hepatic hydatid disease is a goonotic disease caused by Echinococcus granulosus and it is endemic in different parts of the world. This infection is an important public health problem. Although it is distributed throughout the world but common in the livestock grazing regions of the world such as in Central Europe, Africa, South America, Central Asia and China. Here we present the case "30 years old female" with the complaints of right upper abdominal pain for 3 months, nausea & occasional vomiting for 1 month and was admitted under general surgery ward at Mymensingh Medical College Hospital, Mymensingh, Bangladesh on 12th March 2018...
October 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/30487506/a-52-years-old-male-presented-with-acute-kidney-injury-with-hepatitis-after-taking-fish-gallbladder
#10
O F Miah, F A Dowel
A 52 years old male was admitted at National Institute of Kidney Diseases & Urology, Dhaka, Bangladesh on 16th September 2016 with the history of oliguria, nausea, vomiting & swelling of both legs following consumption of rohu fish gall bladder for the permanent remedy of recurrent abdominal discomfort. He was admitted and received antiemetic, proton pump inhibitor. He had azotemia & underwent urgent haemodialysis (HD). Renal function improved over a period of 5 weeks. Fish gallbladder poisoning is quite frequent in several developing country of Southeast Asia...
October 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/30487505/evaluation-of-radiological-outcomes-of-theracal-light-cured-tlc-and-calcium-hydroxide-as-indirect-pulp-capping-agents-in-the-treatment-of-deep-carious-lesion-of-permanent-molar-teeth
#11
M K Parvin, A A Moral, Z H Shikder, M S Alam, A M Bashar
To evaluate the radiographic changes in permanent molar teeth submitted to indirect pulp treatment (IPT) over 12 months period. This prospective comparative study was performed in Department of Conservative Dentistry and Endodontics, Faculty of Dentistry, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from August 2016 to July 2017. Fifty permanent molar teeth with deep caries, but without preoperative signs and symptoms of irreversible pulpitis, received for indirect pulp capping. The teeth were randomly divided into two groups, according to the material used for protection of the dentin- pulp complex: Group A - Twenty five teeth were treated by using Ca(OH)₂ Control and Group B - Twenty five teeth were treated by using theracal light cured (TLC) experimental...
October 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/30487504/echocardiographic-assessment-of-left-atrial-systolic-function-after-percutaneous-mitral-balloon-valvuloplasty-using-tissue-doppler-imaging
#12
M N Hasan, S K Banarjee, S A Ahsan, S M Habib, M Mahmood
Mitral stenosis (MS) affects left atrial (LA) function as a result of hemodynamic and myocardial factors that causes significant symptoms and complications. Conventional echocardiographic methods have been practicing to see the improvement of left atrial function after successful percutaneous mitral balloon valvuloplasty (PMBV). Introduction of tissue doppler imaging allows direct and non-invasive measurement of myocardial velocities. The aim of the study was to evaluate LA functions after PMBV using colour tissue doppler imaging...
October 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/30487503/pattern-of-self-medication-practices-among-rural-population-of-mymensingh
#13
S Sattar, R Quddus, S K Saha
Self-medication is widely practiced in both developed and developing countries and an age old practice. Inappropriate self-medication results in increases resistance of pathogens, wastage of resources and serious health hazards. Present study was conducted to determine the pattern of self-medication practices among rural population. This cross-sectional study was carried out at community pharmacies in a rural area of Mymensingh district, Bangladesh from January 2017 to June 2017. Self-medication data were collected from well stocked licensed retail pharmacies and 20 pharmacies were randomly selected as the study site...
October 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/30487502/laboratory-diagnosis-of-bacterial-vaginosis-and-potential-pathogens-other-than-group-b-streptococcus-in-vaginal-swab-of-pregnant-women-in-dhaka-medical-college-hospital
#14
M N Tarana, S M Shamsuzzaman
Pathogenic microorganisms are important cause of maternal and neonatal infections which are transmitted from colonized vagina of mother. The purpose of the present study was to detect the potential pathogens other than Group B Streptococcus in vaginal swab of pregnant women. This prospective cross sectional study was conducted from July 2013 to June 2014 at Dhaka Medical College Hospital, Dhaka, Bangladesh. A total of 224 vaginal swab samples were studied. Gram stain Nugent score was applied for all vaginal smear to detect bacterial vaginosis...
October 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/30487501/role-of-liver-biopsy-in-the-diagnosis-of-neonatal-cholestasis-due-to-biliary-atresia
#15
M S Hasan, A B Karim, M Rukunuzzaman, A Haque, M A Akhter, U K Shoma, F Yasmin, M A Rahman
Biliary atresia is the commonest cause of cholestatic jaundice. Early diagnosis & surgical correction helps long time survival & prevent development of cirrhosis. This study was conducted to find out the role of liver biopsy in the diagnosis of biliary atresia having positive hepatobiliary scintigraphy as there is chance of false positivity. This cross sectional study was carried out in Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh at Paediatric Gastroenterology & Nutrition Department from January 2014 to June 2015...
October 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/30487500/celiac-disease-in-children-with-chronic-diarrhoea-attending-at-paediatric-gastroenterology-and-nutrition-department-of-bsmmu
#16
S Parveen, A B Karim, S M Rahman, M R Alam, D S Ahmed, M Z Rahman
This descriptive, cross sectional study was conducted at Bangabandhu Sheikh Mujib Medical University from July 2012 to July 2015 to see the occurrence of celiac disease in children with chronic diarrhea. A total of 62 children (age <18 years) attending the Paediatric Gastroenterology and Nutrition department of BSMMU with chronic diarrhoea were enrolled for the study. Mean age of studied children was 7.87±4.67 years. Ratio of the male and female was 2.27:1. Maximum (66.1%) children came from middle income class family...
October 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/30487499/association-of-prolonged-qtc-dispersion-with-diastolic-dysfunction-of-the-left-ventricle-in-patients-with-non-st-segment-elevation-myocardial-infarction
#17
P Karmaker, A K Choudhury, S Hashem, N Alam, G K Paul, M K Siddiqui, R K Datta, M M Ahsan, S I Sikder, C M Kudrat-E-Khuda, S M Faroque, T K Bhowmik, M M Chowdhury
Diastolic function usually declines before systolic function, and this precedes clinical signs in patients with acute coronary syndrome. Therefore, diagnosis of diastolic dysfunction is very important for early diagnosis, follow-up, treatment, and prognostic evaluation in heart failure with preserved ejection fraction (HFpEF) patients. The main objective of the study was to find out association between prolonged QTc dispersion and left ventricular diastolic dysfunction in Non ST Segment Elevation Myocardial Infarction (NSTEMI) patients in HFpEF...
October 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/30487498/pattern-and-risk-factors-of-congenital-anomaly-in-newborn-in-a-tertiary-level-private-medical-college-hospital-bangladesh
#18
M Siddika, S Sen, M N Islam, M K Bhuiyan
The cross sectional study was done to estimate the prevalence of various congenital malformations among the patients delivered in Community Based Medical College Hospital (CBMCH), Mymensingh, Bangladesh and corresponding risk factors were also studied from July 2014 to December 2015. A total of 2560 babies who were born at Community Based Medical College Hospital (CBMCH) were enrolled in this study. The newborn babies were examined and assessed for detection of congenital malformation, system wise distribution and risk factors attributable...
October 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/30487497/wound-coverage-of-infected-open-fracture-of-distal-third-of-tibia-by-distally-based-medial-hemi-soleus-muscle-flap
#19
M S Islam, M T Hossain, M N Uddin, M R Chowdhury, M S Hasan
We conducted a study to evaluate the reliability of the medial hemi-soleus muscle flap for wound coverage of infected open fracture of distal third of tibia. Wound coverage of exposed lower third tibia and ankle region remains a difficult task. Muscle flaps are preferred for infected wounds especially where there are exposed bone, joint and/or tendons. Soleus muscle is a good option for local reconstruction. Soleus being the prime ankle plantar flexor and stabilizer of the ankle in ambulation cannot be sacrificed without significant morbidity...
October 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/30487496/comparison-between-carbetocin-and-oxytocin-in-active-management-of-3rd-stage-of-labour-in-preventing-post-partum-hemorrhage
#20
P Akhter, S N Pal, S Begum
The third stage of labour is considered to be the most critical part of child birth due to the risk of post partum haemorrhage (PPH). To compare the effectiveness of carbetocin and oxytocin in the management of 3rd stage of labour in preventing post partum hemorrhage, this experimental clinical trial was conducted in the Department of Obstetrics and Gynecology, Sir Salimulla Medical College Hospital, Dhaka, Bangladesh from January 2015 to June 2016. Three hundred women undergoing normal vaginal delivery were consecutively enrolled...
October 2018: Mymensingh Medical Journal: MMJ
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