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Mymensingh Medical Journal: MMJ

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https://www.readbyqxmd.com/read/28588188/a-young-boy-with-l-asparaginase-induced-seizure
#1
M A Aziz, N K Singh, M H Rahman, M R Khan, A L Kabir, M Begum
L-Asparaginase is a critical component in the treatment of acute lymphoblastic leukemia in children. It is known to cause coagulation abnormalities, thrombosis and hemorrhage in the central nervous system in addition to vasculitis and hypersensitivity reactions. This syndrome generally occurs after a few weeks of therapy and may occur after L-asparaginase therapy is completed. Seizures are uncommon symptoms. We report a case of seizure associated with L-asparaginase therapy but no evidence of hemorrhagic or thrombotic cerebrovascular events, completed in the department of Hematology of Bangabandhu Sheikh Mujib Medical University during March & April 2016...
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28588187/primary-sclerosing-cholangitis-in-a-young-female
#2
S Biswas, C S Bala, M N Ahasan, M K Chowdhury, M M Hassan, P K Sarkar, M M Sarkar, M Haque
Primary sclerosing cholangitis (PSC) is a liver disease characterized by inflammation and fibrosis of both intrahepatic and extrahepatic bile ducts resulting in cholestasis. Due to nonspecific symptoms it is difficult to diagnose until complication arises. It is common in male and usually associated with other autoimmune diseases. Here, we report a case of PSC in a young female which was initially thought to be drug induced cholestasis without presence of any other autoimmunity.
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28588186/post-operative-supplementary-motor-area-syndrome-a-case-report
#3
A R Satter, D S Asif, S Zannat, S K Gaddam
The supplementary motor area (SMA-proper) is important for the programming and execution of motor, speech, and other elaborative functions. SMA is frequently involved by brain tumors (particularly WHO grade II gliomas). Surgery in this area can be followed by the 'SMA syndrome', characterised by contralateral akinesia and mutism. We present a case of Falcine meningioma in the region of the right SMA which developed SMA syndrome. Our patient showed complete recovery of neurological function but the process was slow with a specific pattern...
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28588185/mucinous-adenocarcinoma-of-the-appendix-a-case-report
#4
M K Khan, R H Talukder, M J Uddin
Primary tumors of the appendix are unusual and most of them are carcinoids. Their main presentation is that of an acute appendicitis or as a palpable mass, mainly in the right lower quadrant. A 40 years old male patient presented in Dhaka Community Medical College Hospital, Dhaka, Bangladesh on 31st October 2013 with mucous adenocarcinoma of the appendix, which primarily presented as heaviness in right lower abdomen and atypical abdominal pain. Diagnosis of the disease was made after right hemicolectomy and histopathological analysis of the specimen...
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28588184/association-of-relationship-between-periodontal-disease-and-cardiovascular-disease
#5
N Johar, S V Dhodapkar, R Kumar, T Verma, A Jajoo
The present study was undertaken to determine the relationship between periodontal and cardiovascular disease. Previous studies have shown some co-relation between the two conditions. We included 186 patients divided into four groups. First two Groups (A1 & A2) were the patients with cardiac disease (100 in numbers) whilst Groups (B1 & B2) (86 in numbers) were treated as controls (without cardiac disease). Following markers of periodontal disease were assessed - plaque index, calculus index, gingival and periodontal index...
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28588183/orlistat-the-lipase-inhibitor-therapy-in-overweight-and-obese-subfertile-women
#6
D Rahman, S M Shahida, T Hussain, A Begum
This experimental study was carried out to evaluate the efficacy of orlistat (a pancreatic lipase inhibitor) therapy over lifestyle change on weight reduction and ovulation in overweight and obese subfertile women. It was carried out in Department of Gynecology and Obstetrics, Bangabandhu Sheikh Mujib Medical University (BSMMU) Dhaka, Bangladesh from August 2015 to January 2016. Subfertile obese and overweight female patients attending the study centre during study period was considered as study population...
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28588182/role-of-computed-tomography-in-the-evaluation-of-nasopharyngeal-mass
#7
A Datta, P P Das, M M Ullah, P G Datta, M S Azad
In Indian subcontinent, all types of nasopharyngeal masses are rare. However, Nasopharyngeal carcinoma is not uncommon in Bangladesh. It is very important to differentiate malignant from benign lesions early in the disease process. In recent years, CT is the primary diagnostic screening modality for the detection of nasopharyngeal pathology. This cross sectional study was carried out in the Department of Radiology & Imaging, BSMMU in collaboration with Department of otolaryngology of the same hospital from July 2012 to June 2014...
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28588181/magnetic-resonance-cholangiopancreatography-mrcp-evaluation-of-obstructive-jaundice-in-comparison-with-endoscopic-retrograde-cholangiopancreatography-ercp
#8
S Imam, M N Islam, N A Khan, S N Mostafa, M S Amin, S Rahman, P Akhter
This cross sectional study was carried out in the department of Radiology and Imaging in collaboration with Department of Gastroenterology of Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh from July 2013 to June 2014 to evaluate the efficacy of Magnetic resonance cholangiopancreatography (MRCP) and ERCP in the management of obstructive jaundice and also to determine diagnostic validity accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of MRCP in evaluation of obstructive jaundice...
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28588180/impact-of-adrenocortical-insufficiency-on-biochemical-parameters-in-haemodynamically-stable-cirrhotic-patients-with-ascites
#9
H Ahmed, M R Karim, R K Paul, M Chowdhury, M S Alam, F Rahman, M A Rouf
Cirrhosis has many complications regardless of the aetiology. Among them, adrenal insufficiency is recently identified entity. A prospective cohort study was done to evaluate the biochemical impact of adrenocortical insufficiency in haemodynamically stable, non-septic, cirrhotic patients with ascites and had been performed at the inpatient of GHPD department, BIRDEM, Dhaka from April 2011 to March 2012. A total of fifty three (53) patients fulfilling inclusion criteria were included in the study. Patients were divided into two groups: Group A (patients of normal adrenal function) and Group B (patients of insufficient adrenal function) and those were followed up for the next 6 months...
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28588179/childhood-wilson-disease-bangladesh-perspective
#10
M Rukunuzzaman, A B Karim, M Nurullah, F Sultana, M W Mazumder, M A Rahman, S B Billah, F Begum, M Oliullah
Wilson's disease (WD) is an autosomal recessive disorder affecting copper metabolism causing copper induced damage to various organs. In children liver is commonly involved. Central nervous system, eyes, RBC, kidneys, brain and bones may also be affected. Aim of the study is to evaluate clinical & laboratory profile of Wilson's disease in children. This cross sectional descriptive study was conducted at the department of Paediatric Gastroenterology and Nutrition, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh, from January 2011 to December, 2013...
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28588178/assessment-of-difficulties-associated-with-endotracheal-intubation-using-modified-mallampati-and-upper-lip-bite-test
#11
D Banik, L Ray, A K Akhtaruzzaman, D K Bhowmick, M S Hossain, M S Islam, M F Haque
This study was aimed at finding the parameters for prediction of difficulty in endotracheal intubation, that are easy to examine and that could better predict difficulty. The current observational prospective, cross sectional study was conducted in the department of Anaesthesia, Analgesia and Intensive Care Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from March 2015 to September 2015 comprising 180 patient of both sexes requiring endotracheal intubation were arranged into two groups, Group A: Modified Mallampati test Group and Group B: Modified Mallampati & upper lip bite test group (combined) Assessment of difficulty in intubation was done by Cormack & Lehane direct Laryngoscopic grading...
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28588177/antibiotic-susceptibility-pattern-of-bacteria-isolated-from-various-specimens-of-patients-with-hematological-malignancy
#12
J Roy, D C Nag
Infection is a life threatening complication in patients with hematological malignancy. So, proper treatment of infection with suitable antibiotic is very important in these patients. The aim of this study was to determine the antibiotic susceptibility of bacteria isolated from various specimens of patients with hematological malignancy, so that, an appropriate regimen of empiric antibiotic treatment can be established for these patients. This observational study was done in the Department of Microbiology and Immunology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from March 2012 to August 2012...
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28588176/evaluation-of-bcr-abl-gene-rearrangement-among-bangladeshi-chronic-myeloid-leukaemia-patients
#13
T F Dipta, A Datta, A Tarif, M A Mottalib, A M Yunus, M A Muttalib, S Choudhury, M A Islam
Chronic Myeloid Leukaemia (CML) is a clonal myeloproloferative disorder. Presence of molecular translocation t (9; 22) in CML patients can be confirmed by Reverse Transcriptase Polymerase Chain Reaction (RT-PCR). Among haematological malignancies CML is the commonest leukaemia of adults in Asia. Despite this, there are very few studies published from Bangladesh, documenting the frequency of bcr-abl fusion transcripts. So, we would like to perform this observational study to evaluate bcr-abl fusion transcripts and demographic status among RT-PCR positive chronic phase CML patients at BIRDEM & other two centers of Dhaka city, Bangladesh where patients admitted from different districts of Bangladesh in the period of January 2010 to June 2012...
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28588175/her2-status-in-gastric-and-gastroesophageal-junction-adenocarcinoma
#14
F A Rima, M Hussain, N Haque, R K Dewan, N Rahman, M A Jinnah, R Jeba, F Chowdhury
Gastric carcinoma is a biologically heterogenous disease and survival varies among the patients with same stage. Recent studies have shown that a subset of gastric and gastroesophageal junction adenocarcinoma over express the HER2/neu protein and these patients can be treated by monoclonal antibody against HER2/neu protein. The purpose of this study was to detect the frequency of HER2 expression in gastric and gastroesophageal junction adenocarcinoma and to evaluate the relationship between HER2 expression and clinicopathological features in these patients...
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28588174/c-reactive-protein-crp-as-a-single-biomarker-for-diagnosis-of-neonatal-sepsis-a-comprehensive-meta-analysis
#15
K H Shabuj, J Hossain, S C Moni, S K Dey
Neonatal sepsis (NS) is a life-threatening disorder and an important cause of morbidity and mortality in neonates. Blood culture, the gold standard for diagnosis of neonatal sepsis is costly, not available at all centres and test result not readily available. CRP is low cost diagnostic test for neonatal sepsis which is possible to perform at all centres and test result is easily available. We aimed to evaluate the usefulness of C-reactive protein (CRP) measurement to identify neonatal sepsis. We conducted this meta-analysis to investigate the diagnostic accuracy of the CRP in neonatal sepsis...
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28588173/macrophage-activation-syndrome-in-paediatric-rheumatic-diseases
#16
M I Islam, M K Talukder, M M Islam, K Laila, S A Rahman
Macrophage activation syndrome (MAS) is a potentially fatal complication of rheumatic disorders, which commonly occurs in systemic juvenile idiopathic arthritis (sJIA).This study was carried out with the aims of describing the clinical features, laboratory findings and outcomes of MAS associated with paediatric rheumatic diseases in the Department of Paediatrics, Bangabandhu Sheikh Mujib Medical University (BSMMU) and compare these results with previous studies on MAS. This retrospective study was conducted in the paediatric rheumatology wing of the Department of Paediatrics, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh...
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28588172/primary-angioplasty-for-the-treatment-of-acute-st-elevated-myocardial-infarction-single-centre-experience
#17
K N Khan, M H Khan, R Rahman, M A Rashid, S Z Haque, Z Zakia
Worldwide primary angioplasty is a recommended strategy of reperfusion in patient with acute myocardial infarction as because it ensures reperfusion of the infarct-related vessels more than 90% whereas, with thrombolytics it is only 60-70%. This retrospective observational study includes all patients treated with primary angioplasty at United Hospital from Between March 2007 to January 2011. Total 114 consecutive patients with acute myocardial infarction were treated with primary angioplasty included. Those presented beyond 12 hours of onset of chest pain, in cardiogenic shock, resuscitate and intubated before the procedure were excluded from the study...
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28588171/clinical-and-laboratory-predictors-of-esophageal-varices-in-children-with-chronic-liver-disease
#18
M I Hasan, M Rukunuzzaman, M Nurullah, F Sultana
Esophageal varices are a serious consequence of portal hypertension in patients with chronic liver diseases. Several studies have evaluated possible noninvasive markers of esophageal varices to reduce the number of unnecessary endoscopies in patients with chronic liver disease. Aim of this study was to identify clinical and laboratory predictors of esophageal varices in children with chronic liver disease. This cross sectional observational study was done at Pediatric Gastroenterology and Nutrition Department of Bangabandhu Sheikh Mujib Medical University, Dhaka, over a period of 6 months...
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28588170/early-postoperative-parathyroid-hormone-level-as-a-predictor-of-hypocalcaemia-after-total-thyroidectomy
#19
S B Sharif, S A Rakib, K S Naznin, S M Alam
Postoperative transient hypocalcaemia is a common squeal after total thyroidectomy usually due to parathyroid insufficiency. Objective of this study is to find out the optimum cut-off value of parathyroid hormone (PTH) level in early postoperative period as a best predictor for hypocalcaemia. This prospective observational study was carried out from July 2013 to July 2014 in the Department of Surgery Sir Salimullah Medical College & Mitford Hospital (SSMC&MH), in collaboration with department of Otolaryngology SSMC&MH, department of Otolaryngology Bangabandhu Sheikh Mujib Medical University (BSMMU) and department of Otolaryngology Dhaka Medical College & Hospital (DMC&H), Dhaka...
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28588169/outcome-of-surgical-drainage-of-the-pancreatic-duct-in-chronic-pancreatitis
#20
S R Islam, S Rahman, S Rahman, H Kumar, S A Sarkar
Abdominal pain, one of the major symptoms of chronic pancreatitis, is believed to be caused by obstruction of the pancreatic duct system by stones or strictures. This results in increased intraductal pressure and parenchymal ischemia. Surgical decompression of the duct and ductal drainage can achieve best pain relieve and slow the progression of the disease. We want to share our experience of surgical drainage of pancreatic duct in chronic pancreatitis in our hospital. We studied 20 cases operated in our hospital between January 2010 and October 2015...
April 2017: Mymensingh Medical Journal: MMJ
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