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Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association

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https://www.readbyqxmd.com/read/30381495/predictors-of-failure-of-endoscopic-retrograde-cholangiography-in-clearing-bile-duct-stone-on-the-initial-procedure
#1
Majid A Almadi, Mohanned Eltayeb, Salem Thaniah, Faisal Alrashed, Mohammad A Aljebreen, Othman R Alharbi, Nahla Azzam, Abdulrahman M Aljebreen
Background/Aims: The aim of this study is to predict cases where the clearance of the biliary system from stones at the initial endoscopic retrograde cholangiopancreatography (ERCP) might be of value for better risk-stratifying patients. We attempted to identify factors that are associated with a higher failure rate of clearing the biliary system on the index ERCP. Patients and Methods: This is a retrospective study from January 2008 to January 2015. All patients with bile duct stones confirmed on ERCP were included in this study...
October 31, 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/30381494/accuracy-of-invasive-and-noninvasive-methods-of-helicobacter-pylori-infection-diagnosis-in-saudi-children
#2
Mohammed Hasosah
Background/Aim: Helicobacter pylori (H. pylori) infection is one of the most common chronic infections in the world. The prevalence of H. pylori is high in Saudi Arabia, but there are no studies in children on the accuracy of invasive and noninvasive methods to diagnose H. pylori infection. The aim of this study was to evaluate the accuracy of six methods for diagnosis of H. pylori infection; four invasive [rapid urease test (RUT), histology, antral nodularity (AD), and biopsy culture (BC)] and two noninvasive methods [serologic test and stool antigen test (SAT)]...
October 31, 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/30381493/%C3%AE-smooth-muscle-actin-expression-predicts-the-outcome-of-kasai-portoenterostomy-in-biliary-atresia
#3
Priya Ramachandran, Ashitha K Unny, Mukul Vij, Mohamed Safwan, Muthukrishnan Saravana Balaji, Mohamed Rela
Background/Aims: Biliary atresia (BA) is a cholangio-destructive disease of the infant liver presenting with features of obstructive cholangiopathy. The Kasai portoenterostomy (KPE) is the first line of management. The aim of our study was to identify the characteristic features of liver histology in BA that impact the outcome of KPE. Patients and Methods: Data from 30 consecutive children was retrieved from our prospectively maintained database of children undergoing KPE...
October 31, 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/30264737/the-saudi-association-for-the-study-of-liver-diseases-and-transplantation-clinical-practice-guidelines-for-management-of-autoimmune-hepatitis
#4
Abdulrahman A Aljumah, Badr Al Jarallah, Ali Albenmousa, Abdullah Al Khathlan, Adnan Al Zanbagi, Mohammed Al Quaiz, Bandar Al-Judaibi, Khalid Nabrawi, Waleed Al Hamoudi, Mohammed Alghamdi, Hind Fallatah
No abstract text is available yet for this article.
September 27, 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/30226482/a-meta-analysis-of-early-oral-refeeding-and-quickly-increased-diet-for-patients-with-mild-acute-pancreatitis
#5
Jiran Zhang, Sha Zhu, Dingyu Tan, Aiwen Ma, Yan Yang, Jiyang Xu
Background/Aim: The objective of the study is to clarify whether early oral refeeding (EORF) and quickly increasing diet (QID) are of benefit to patients with mild acute pancreatitis compared with a traditional oral refeeding strategy. Materials and Methods: Studies were searched in PubMed, Cochrane library, ScienceDirect, SpringerLink, China Biology Medicine disc and Embase. A meta-analysis was then performed, using relapse of abdominal pain, nausea/vomiting, and length of hospital stay (LOHS) as the evaluation indices...
September 18, 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/30226481/low-expression-of-muc2-is-associated-with-longer-disease-free-survival-in-patients-with-colorectal-carcinoma
#6
Jaudah Al-Maghrabi, Shabnum Sultana, Wafaey Gomaa
Background/Aim: The objective of this study was to investigate the relationship between MUC2 immunostaining and clinicopathological characteristics in a subset of colorectal carcinomas (CRCs). Materials and Methods: A total of 128 CRCs, 50 local nodal metastases, and 42 normal colonic mucosae were retrieved from the archives at the Department of Pathology at King Abdulaziz University, Jeddah, Saudi Arabia. Immunohistochemistry was performed using anti-MUC2 antibody...
September 18, 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/30226480/water-exchange-versus-air-insufflation-for-colonoscopy-a-meta-analysis
#7
Yang Liu, Qing-Ke Huang, Xiu-Li Dong, Piao-Piao Jin
Background/Aims: To compare water exchange (WE) method with conventional air insufflation (AI) method for colonoscopy, evaluating the technical quality, screening efficacy, and patients' acceptance. Materials and Methods: Electronic databases were systematically searched for randomized controlled trials comparing WE colonoscopy with AI colonoscopy. The pooled data of procedure-associated and patient-related outcomes were assessed, using the weighted mean difference (WMD) with 95% confidence interval (CI) for continuous variables and relative risk (RR) with 95% CI for dichotomous variables, respectively...
September 18, 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/30178779/the-puzzling-relationship-between-human-leukocyte-antigen-hla-genes-and-celiac-disease
#8
EDITORIAL
Carlo Catassi, Giulia Naspi Catassi
No abstract text is available yet for this article.
September 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/30117493/extraintestinal-manifestations-of-pediatric-inflammatory-bowel-disease-in-saudi-arabia
#9
LETTER
Mahmood D Al-Mendalawi
No abstract text is available yet for this article.
September 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/29956690/genetic-susceptibility-for-celiac-disease-is-highly-prevalent-in-the-saudi-population
#10
Abdulrahman Al-Hussaini, Hanan Alharthi, Awad Osman, Nezar Eltayeb-Elsheikh, Aziz Chentoufi
Background/Aim: To determine the frequency of celiac disease (CD)-predisposing human leukocyte antigen (HLA)-DQ genotypes in the Saudi population, where the prevalence of CD is 1.5% as recently reported in a mass screening study. Patients and Methods: In a cross-sectional population-based study, a total of 192 randomly selected healthy school children (97 females, mean age 10.5 ± 2.2 years, all negative for tissue transglutaminase-IgA) were typed for D QA1 and D QB1 genes by polymerase chain reaction sequence-specific oligonucleotide probes...
September 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/29873320/mirizzi-s-syndrome-a-scoring-system-for-preoperative-diagnosis
#11
Rachana D Tataria, Hrishikesh P Salgaonkar, Gaurav Maheshwari, Premashish J Halder
Background/Aim: Mirizzi's syndrome (MS) is an unusual complication of gallstone disease and occurs in approximately 1% of patients with cholelithiasis. Majority of cases are not identified preoperatively, despite the availability of modern imaging techniques. A preoperative diagnosis can forewarn the operating surgeon and avoid bile duct injuries in cases of complicated cholecystitis. A preoperative scoring system helpful and hence, we aim to devise a scoring system based on clinical, biochemical, and imaging features to predict the diagnosis of MS in cases of complicated cholecystitis...
September 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/29873319/is-water-exchange-superior-to-water-immersion-for-colonoscopy-a-systematic-review-and-meta-analysis
#12
REVIEW
Zhihao Chen, Zhengqi Li, Xinying Yu, Guiqi Wang
Background/Aims: Recently, water exchange (WE) instead of water immersion (WI) for colonoscopy has been proposed to decrease pain and improve adenoma detection rate (ADR). This systematic review and meta-analysis is conducted to assess whether WE is superior to WI based on the published randomized controlled trials (RCTs). Materials and Methods: We searched studies from PubMed, Cochrane Central Register of Controlled Trials, EMBASE, and MEDLINE. Only RCTs were eligible for our study...
September 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/29873317/correlated-non-nuclear-cox2-and-low-her2-expression-confers-a-good-prognosis-in-colorectal-cancer
#13
Fei-Fei Zhou, Rong Huang, Jun Jiang, Xiao-Hong Zeng, Shu-Qian Zou
Background/Aims: COX2 and HER2 are shown to be critical in the regulation of cancer progression. However, the prognostic value of nuclear COX2 in colorectal cancer (CRC) and its relationship with HER2 still remains unknown. In this study, the expression and biological significance of COX2 and HER2 were evaluated in CRC at mRNA and protein levels. Materials and Methods: RNA-Seq data of CRC were downloaded from TCGA, and 229 CRC and 50 non-cancerous subjects were enrolled in this study...
September 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/29873316/the-role-of-the-plr-nlr-combination-in-the-prediction-of-the-presence-of-helicobacter-pylori-and-its-associated-complications
#14
Mustafa Kaplan, Ihsan Ates, Mahmut Yuksel, Mehmet F Arikan, Gulden Aydog, Nesrin Turhan, Volkan Gökbulut, Ertugrul Kayacetin
Background/Aim: The aim of this study was to investigate the role of the platelet-to-lymphocyte ratio (PLR)-neutrophil-to-lymphocyte ratio (NLR) combination, in the prediction of the presence of Helicobacter pylori (HP) and its associated complications in the gastrointestinal system. Patients and Methods: In all, 1289 patients who underwent esophagogastroduodenoscopy and biopsy for HP were included in the study. Results: The ratio of patients with moderate and severe chronic gastritis was higher in HP (+) group than HP (-) group...
September 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/29806596/gastric-adenocarcinoma-expressing-human-epidermal-growth-factor-receptor-in-south-asian-population
#15
Asma Shabbir, Muhammad Asif Qureshi, Abdullah Bin Khalid, Talat Mirza, Asma Shaikh, Syed Mehmood Hasan
Background/Aim: Gastric cancer is the third leading cause of cancer mortality worldwide. Human epidermal growth factor (Her-2/neu) has shown strong therapeutic implication in breast cancer. Although the prevalence of Her-2/neu over-expression in gastric cancer has been reported across the world, it is still unknown from South Asia. The aim of this study is to evaluate Her-2/neu expression in gastric adenocarcinomas and to correlate with various clinicopathological variables. Patients and Methods: A total of 95 consecutive patients undergoing endoscopic biopsy or gastrectomy were recruited in this study...
September 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/29676288/predictors-of-morbidity-and-mortality-post-emergency-abdominal-surgery-a-national-study
#16
Afnan Altamimi, Mazen Hassanain, Thamer Nouh, Khawlah Ateeq, Murad Aljiffry, Abrar Nawawi, Ghaith Al Saied, Mohammed Riaz, Huda Alanbar, Abdullah Altamimi, Saeed Alsareii, Mashael Al-Mousa, Abeer Al-Shammari, Saleh Alnuqaydan, Amal Ghzwany
Background/Aim: Emergency surgeries have increased in Saudi Arabia. This study examines these surgeries and associated complications. Patients and Methods: This was a prospective multicenter cohort study of patients undergoing emergency intraperitoneal surgery from the eight health sectors of Saudi Arabia. Patients' data were collected over 14 days. Results: In total, 283 patients were included (163 men [54.06%]). The majority of cases were open surgery (204 vs...
September 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/30136703/the-characteristics-of-83-giant-peptic-ulcers-in-chinese-children-evaluation-and-follow-up
#17
Zifei Tang, Jieru Shi, Min Ji, Peng Shi, Zhiheng Huang, Ying Huang
Background/Aims: Giant peptic ulcers (GPUs) are detrimental for all patients, especially for children. However, few reports have described GPUs in children. This study aims to evaluate the characteristics of GPUs in Chinese children and to identify risk factors. Patients and Methods: We retrospectively analyzed patients at the Children's Hospital of Fudan University from April 2014 to August 2017. Patients with GPUs (>2.0 cm) were included in the study, and the clinical data, pathological characteristics and presence of Helicobacter pylori (H...
August 20, 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/30117492/radiofrequency-ablation-versus-surgical-resection-in-elderly-patients-with-early-stage-hepatocellular-carcinoma-in-the-era-of-organ-shortage
#18
Bin Yu, Youming Ding, Xiaofeng Liao, Changhua Wang, Bin Wang, Xiaoyan Chen
Background/Aims: To compare the survival benefits of surgical resection (SR) with those of radiofrequency ablation (RFA) in elderly patients (≥65 years) with single hepatocellular carcinoma (HCC) ≤5 cm. Patients and Methods: Using the Surveillance, Epidemiology, and End Results database, a total of 461 patients who underwent SR and 575 patients who underwent RFA were enrolled from 2004 to 2012. Overall survival (OS) and liver-cancer-specific survival (LCSS) comparisons were conducted between the two groups before and after propensity score matching (PSM)...
August 14, 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/30117491/in-hospital-post-transplant-acute-hepatitis-a-viral-hav-infection-in-a-liver-transplant-recipient-who-was-hav-seropositive-pre-transplant
#19
Julie Zhu, Fatema Alalkim, Trana Hussaini, Siegfried R Erb, Vladimir Marquez, Mel Krajden, Douglas Webber, Eric M Yoshida
Acute hepatitis A viral (HAV) infection is rare in the liver transplant population due to recommended pre-transplant vaccinations. We report a case of acute hepatitis A infection in a liver transplant recipient. This individual had immunity to hepatitis A with protective IgG antibodies and presented with abnormal liver biochemistry in the post-transplant in-patient setting. Hepatitis A infection was confirmed by positive HAV IgM whereas other etiologies, including acute cellular rejection, were ruled out by laboratory tests and liver biopsies...
August 14, 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/30117490/treatment-efficacy-of-ledipasvir-sofosbuvir-for-8-weeks-in-non-cirrhotic-chronic-hepatitis-c-genotype-4-patients
#20
Mohammed A Babatin, Abdullah S AlGhamdi, Abdullah M Assiri, Haziz AlBiladi, Hammad S AlOthmani, Mohammed H Mogharbel, Wedad Mahallawi, Tarik Asselah, Faisal M Sanai
Background/Aims: Ledipasvir/sofosbuvir (LDV/SOF) combination is administered for 12 to 24 weeks to treat hepatitis C virus (HCV); guidelines recommend 8 weeks treatment duration for HCV genotype (GT) 1 infection based on the patient's baseline characteristics. Data on treating HCV GT4 with LDV/SOF are limited. In this prospective cohort study, the efficacy and safety of 8 weeks treatment duration with LDV/SOF was evaluated in HCV GT4 patients in Saudi Arabia. Patients and Methods: Treatment-naïve, non-cirrhotic HCV GT4 patients received LDV/SOF for 8 weeks...
August 14, 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
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