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Canadian Journal of Urology

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https://www.readbyqxmd.com/read/29524979/bilateral-hydronephrosis-and-acute-kidney-injury-secondary-to-pelvis-lipomatosis
#1
Wesley Baas, Blake O'Connor, Ahmed El-Zawahry
A 57-year-old African American male presented with vague abdominal pain and bilateral flank pain. The patient was found to have bilateral hydronephrosis and significant renal function impairment secondary to pelvic lipomatosis. Pelvic lipomatosis represents a clinically-diagnosed unique cause of ureteral obstruction and subsequent renal impairment. We present a case report of newly diagnosed pelvic lipomatosis, the clinical and imaging characteristics for diagnosis, and its conservative management with serial ureteral stent exchanges...
February 2018: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29524978/t4-urothelial-carcinoma-in-undiagnosed-closed-bladder-exstrophy-in-a-post-menopausal-female
#2
Brian J McArdle, Patricia Vidal, Sarah P Psutka, Courtney M P Hollowell
It is rare to see an adult presenting with exstrophy of the bladder. Malignant conversion in exstrophy occurs in 4%, with adenocarcinoma as the most common histopathology. We report the first case of metastatic high grade urothelial carcinoma with squamous and sarcomatoid differentiation arising from undiagnosed, closed bladder exstrophy in a female at advanced age with associated bilateral deep vein thrombosis and clot retention. The patient developed clinical progression of disease despite neoadjuvant gemcitabine-cisplatin and salvage (or palliative) radiotherapy...
February 2018: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29524977/retroperitoneal-leydig-cell-tumor-recurrence-presenting-14-years-after-orchiectomy
#3
Nicholas H Chakirya, Phil W Raess, Kevin Turner, Jason C Hedges, Jen-Jane Liu
Malignant Leydig cell tumor is a rare entity that has been previously described as rapidly progressive and uniformly fatal. We present the case of a malignant Leydig cell tumor that presented 14 years after orchiectomy with an isolated retroperitoneal metastasis. Our patient underwent a retroperitoneal lymph node dissection and has been free of recurrence or progression at 12 months of follow up. Additionally, we describe the symptomatic hormone dysfunction experienced by our patient as a result of his tumor...
February 2018: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29524976/fluoroless-ureteroscopy-for-definitive-management-of-distal-ureteral-calculi-randomized-controlled-trial
#4
Ahmed Mohey, Mohamed Alhefnawy, Mostafa Mahmoud, Rabea Gomaa, Tarek Soliman, Shabieb Ahmed, Yasser A Noureldin
INTRODUCTION: To assess the conversion rate during fluoroless-ureteroscopy (URS) and evaluate the feasibility, safety, and efficacy of fluoroless-URS as a definitive management of distal ureteral calculi. MATERIAL AND METHODS: Between May 2013 and August 2015, patients with radio-opaque distal ureteral calculi of ≤ 1 cm in size were randomized to undergo fluoroless-URS or standard URS. Patients with previous ureteral surgery, ureteral kinking, ureteral stricture, single kidney, additional proximal ureteral or renal calculi, uncontrolled coagulopathy, and/or congenital anomalies of the urinary tract were excluded...
February 2018: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29524975/urine-kidney-injury-markers-do-not-increase-following-gastric-bypass-a-multi-center-cross-sectional-study
#5
Bryan D Hinck, Ricardo Miyaoka, James E Lingeman, Dean G Assimos, Brian R Matlaga, Rocky Pramanik, John Asplin, Benjamin Cohen, Manoj Monga
INTRODUCTION: To determine if markers of kidney injury correlate with urinary oxalate excretion. If so, such biomarkers might be early predictors of oxalate nephropathy. Gastric bypass surgery for obesity is known to be associated with postoperative hyperoxaluria, which can lead to urolithiasis and kidney damage. MATERIALS AND METHODS: Patients were recruited from four large academic centers > 6 months following completion of gastric bypass surgery. Patients provided a spot urine sample for analysis of three markers of kidney injury: 8-iso-Prostaglandin F2 α, N-acetyl- β -D-Glucosaminidase, and Neutrophil gelatinase-associated lipocalin...
February 2018: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29524974/african-american-men-with-prostate-cancer-have-larger-tumor-volume-than-caucasian-men-despite-no-difference-in-serum-prostate-specific-antigen
#6
Jay G Fuletra, Anastasiya Kamenko, Frederick Ramsey, Daniel D Eun, Adam C Reese
INTRODUCTION: Prior studies suggest that among men with low grade prostate cancer, African Americans (AA) produce less prostate-specific antigen (PSA) than Caucasians. We investigated racial differences in PSA, PSA density (PSAD), and tumor volume among men with prostate cancer, regardless of tumor grade. These racial differences, if present, would suggest that AA men may benefit from different screening, surveillance, and treatment regiments compared to Caucasians. MATERIALS AND METHODS: We identified men from our institutional prostate cancer database that underwent radical prostatectomy between 2012 and 2015...
February 2018: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29524973/implications-of-postoperative-pulmonary-aspiration-following-major-urologic-surgery
#7
Eric J Kirshenbaum, Robert H Blackwell, Belinda Li, Anai N Kothari, Paul C Kuo, Robert C Flanigan, Alex Gorbonos, Gopal N Gupta
INTRODUCTION: The purpose of this article is to assess the incidence of pulmonary aspiration following major urologic surgery, predictors of an aspiration event, and subsequent clinical outcomes. MATERIALS AND METHODS: The Healthcare Cost and Utilization Project State Inpatient Database for California between 2007-2011 was used to identify cystectomy, prostatectomy, partial and radical nephrectomy patients. Aspiration events were identified within 30 days of surgery...
February 2018: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29524972/sociodemographic-and-survival-disparities-for-histologic-variants-of-bladder-cancer
#8
Joshua S Jue, Tulay Koru-Sengul, Kevin J Moore, Feng Miao, Mahmoud Alameddine, Bruno Nahar, Sanoj Punnen, Dipen J Parekh, Chad R Ritch, Mark L Gonzalgo
INTRODUCTION: To investigate the impact of perioperative factors on overall survival among patients with histologic variants of bladder cancer treated with radical cystectomy. MATERIALS AND METHODS: The National Cancer Data Base was utilized to identify patients diagnosed with muscle-invasive bladder cancer (cT2-4, N0, M0) from 2004-2013. Variant histology bladder cancers (non-mucinous adenocarcinoma, mucinous/signet ring adenocarcinoma, micropapillary urothelial carcinoma, small cell carcinoma, and squamous cell carcinoma) were compared to urothelial carcinoma with respect to overall survival...
February 2018: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29524971/analysis-of-evidence-within-the-aua-s-clinical-practice-guidelines
#9
Samuel G Antoine, Alexander C Small, James M McKiernan, Ojas Shah
INTRODUCTION: Surgical subspecialty societies release clinical practice guidelines (CPGs) to provide topic-specific recommendations to healthcare providers. We hypothesize that there may be significant differences in statement strength and evidence quality both within the American Urological Association (AUA) guidelines and compared to those published by the American Academy of Orthopedic Surgeons (AAOS) and American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS). MATERIALS AND METHODS: CPGs issued through 2017 were extracted from the AUAnet...
February 2018: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29524970/analysis-of-bladder-cancer-subtypes-in-neurogenic-bladder-tumors
#10
Quentin Manach, Olivier Cussenot, Morgan Rouprêt, Xavier Gamé, Emmanuel Chartier-Kastler, Christine Reus, Philippe Camparo, Eva Compérat, Véronique Phé
INTRODUCTION: To establish if the validated tumor biomarkers of luminal and basal bladder cancers in non neuro-urological patients are applicable to a neuro-urological population. MATERIALS AND METHODS: We retrieved bladder cancer samples from neuro-urological patients (n = 20) and non-neurological controls (n = 40). The expression of GATA3 and CK5/6 was analyzed using immunohistochemistry of microarray tissue sections. We also assessed the correlation between previous biomarker expression, gender, age, tumor stage (non-muscle-invasive bladder cancer (NMIBC)/muscle-invasive bladder cancer (MIBC)), squamous-cell differentiation and basal/luminal subtypes using Pearson's correlation coefficient (r)...
February 2018: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29524969/identifying-and-managing-the-risks-of-medical-ionizing-radiation-in-endourology
#11
Todd Yecies, Timothy D Averch, Michelle J Semins
INTRODUCTION: The risks of exposure to medical ionizing radiation is of increasing concern both among medical professionals and the general public. Patients with nephrolithiasis are exposed to high levels of ionizing radiation through both diagnostic and therapeutic modalities. Endourologists who perform a high-volume of fluoroscopy guided procedures are also exposed to significant quantities of ionizing radiation. The combination of judicious use of radiation-based imaging modalities, application of new imaging techniques such as ultra-low dose computed tomography (CT) scan, and modifying use of current technology such as increasing ultrasound and pulsed fluoroscopy utilization offers the possibility of significantly reducing radiation exposure...
February 2018: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29524968/letter-to-the-editor
#12
EDITORIAL
J G Blaivas, J F Tsui, G Mekel, M S Benedon, B Li, F M Friedman, J M Weinberger, J Weedon, J P Weiss
No abstract text is available yet for this article.
February 2018: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29524967/legends-in-urology
#13
EDITORIAL
Per-Anders Abrahamsson
No abstract text is available yet for this article.
February 2018: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29524966/resistance-to-change-resistance-is-futile-change-is-inevitable-so-why-is-it-so-challenging
#14
EDITORIAL
Timothy D Averch
No abstract text is available yet for this article.
February 2018: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29260644/recurrent-renal-cell-carcinoma-presenting-as-a-solitary-left-ventricular-mass
#15
Lindsay Wilde, Praveen Mehrotra, Jean Hoffman-Censits
A 73-year-old male with a remote history of renal cell carcinoma presented with an asymptomatic left ventricular mass. Biopsy of the mass revealed a late recurrence of his renal cell carcinoma. Given the size and location of the mass, resection was not possible. Treatment with pazopanib was initiated with good clinical response.
December 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29260643/blueprint-unknown-a-case-for-multidisciplinary-management-of-advanced-penile-mycosis-fungoides
#16
Jonathan S O'Brien, Todd Manning, Marlon Perera, H Miles Prince, Nathan Lawrentschuk
A 64-year-old man presented with a 2 week history of progressive phimosis and painful ulcer on his penile meatus. He underwent penile preserving excision, and subsequent pathological examination confirmed T-cell non-Hodgkin lymphoma with immunohistochemical features of large cell transformation of mycosis fungoides. The penis was further treated with local external beam radiotherapy consisting of 27 Gy in 15 fractions and systemic mini-CHOP chemotherapy. An organ-preserving tissue response has since been achieved...
December 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29260642/subcutaneous-emphysema-following-cystoscopic-clot-evacuation
#17
Madeline Cancian, Joseph Brito, Vincent Harisaran
Gross hematuria is a common urologic problem which often requires surgical intervention. While generally a safe procedure, clot evacuation can have serious complications. Here we describe the case of an 85-year-old male who developed extensive subcutaneous emphysema following a small extraperitoneal bladder perforation during a clot evacuation. While our patient did well with expectant management, subcutaneous emphysema can lead to serious complications and any endourologic procedure should be stopped once crepitus is noted...
December 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29260641/benign-fibrous-pseudotumor-resulting-in-orchiectomy-despite-intraoperative-frozen-section
#18
Tomy Y Perez, Brian J O'Hara, Irvin H Hirsch
Fibrous pseudotumors are rare benign lesions that originate within the paratesticular tissues. Local excision is the preferred method of treatment of these tumors over radical orchiectomy, however a definitive diagnosis must be made beforehand given the similarity of these tumors to malignant entities. We present a case of fibrous pseudotumor of the tunica vaginalis and cauda epididymis. A diagnosis of fibrous pseudotumor could not be established despite the use of intraoperative frozen section, therefore necessitating radical orchiectomy...
December 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29260640/ultrasound-self-referral-does-not-increase-utilization-in-pediatric-urology
#19
Lesli Nicolay, Adam S Howe, Lane S Palmer
INTRODUCTION: Costs of radiologic imaging are rising. The goal of this study is to examine the utilization practices of pediatric urologists who have access to in-office ultrasound imaging when managing children with primary hydronephrosis. MATERIALS AND METHODS: A retrospective cross sectional study was performed of children ≤ 5 years old with an isolated diagnosis of hydronephrosis. Ultrasound utilization was evaluated by tallying the number of ultrasounds obtained during the time each child was followed...
December 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29260639/importance-of-counseling-and-patient-selection-in-treatment-of-male-stress-incontinence
#20
EDITORIAL
David E Rapp
No abstract text is available yet for this article.
December 2017: Canadian Journal of Urology
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