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Parkinsonism & related Disorders

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https://www.readbyqxmd.com/read/28094104/zolpidem-in-movement-disorders-after-cardiac-arrest
#1
LETTER
W O Arruda, M S Silva, D B Bertholdo, R P Munhoz, H A G Teive
No abstract text is available yet for this article.
January 11, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28094106/expanded-phenotype-and-hippocampal-involvement-in-a-novel-compound-heterozygosity-of-adult-pla2g6-associated-neurodegeneration-park14
#2
LETTER
Joan Philipp Michelis, Elke Hattingen, Florian C Gaertner, Martina Minnerop, Frank Träber, Saskia Biskup, Thomas Klockgether, Sebastian Paus
No abstract text is available yet for this article.
January 10, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28094105/sonographic-alteration-of-substantia-nigra-is-related-to-parkinsonism-predominant-course-of-x-linked-dystonia-parkinsonism
#3
Uwe Walter, Raymond Rosales, Alessandro Rocco, Ana Westenberger, Aloysius Domingo, Criscely L Go, Norbert Brüggemann, Christine Klein, Lillian V Lee, Dirk Dressler
INTRODUCTION: X-linked recessive dystonia-parkinsonism (XDP, DYT3) is highly prevalent in the Philippines and manifests with varying phenotype. We sought to evaluate the significance of transcranial brain sonography as a biomarker for parkinsonism-predominant phenotype. METHODS: 90 Filipino participants were enrolled into a cross-sectional study: 39 patients with XDP, 21 asymptomatic first-degree relatives of XDP patients, and 30 healthy control subjects. Echogenicity of the substantia nigra and the lenticular nuclei was digitally quantified...
January 10, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28089264/development-and-validation-of-the-deep-brain-stimulation-impairment-scale-dbs-is
#4
Franziska Maier, Catharine J Lewis, Carsten Eggers, Andrea A Kühn, Henriette Krug, Jens Volkmann, Anna D Kirsch, Lars Wojtecki, Alfons Schnitzler, Günther Deuschl, Joachim K Krauss, Christiane Woopen, Lars Timmermann
BACKGROUND: Bilateral deep brain stimulation of the subthalamic nucleus (STN-DBS) has considerable influence on motor and non-motor symptoms in Parkinson's disease (PD). While improvements in motor functioning can be easily assessed with general quality of life questionnaires, the measurement of specific STN-DBS-associated impairments often remains insufficient. Hence, we aimed to develop a questionnaire that measures STN-DBS-related impairments. METHODS: The development of the (STN-)DBS Impairment Scale (DBS-IS) consisted of four steps...
January 6, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28073679/identification-of-early-neurodegenerative-change-in-presymptomatic-spinocerebellar-ataxia-type-1-a-diffusion-tensor-imaging-study
#5
LETTER
Yeon Ji Yoo, Jeehae Oh
We report a 41-year-old man of presymptomatic spinocerebellar ataxia type 1. Diffusion tensor imaging (DTI) verified decreased fractional anisotropy of cerebellar afferent and efferent pathways compared to 5 age-matched healthy controls while conventional MRI revealed normal brain. DTI was valuable in detection of early microstructural damage of cerebellar pathways.
January 3, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28063684/abnormal-dopamine-transporter-imaging-in-adult-onset-niemann-pick-disease-type-c
#6
LETTER
Joanne Terbeek, Philippe Latour, Koen Van Laere, Wim Vandenberghe
No abstract text is available yet for this article.
January 3, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28065403/medication-errors-in-parkinson-s-disease-inpatients-in-the-basque-country
#7
Unax Lertxundi, Arantxa Isla, María Ángeles Solinís, Saioa Domingo- Echaburu, Rafael Hernandez, Javier Peral-Aguirregoitia, Juan Medrano, Juan Carlos García-Moncó
INTRODUCTION: Parkinson's disease (PD) medication errors, including both missing dopaminergic drug doses and antidopaminergic usage, have been suggested as risk factors for prolonged hospital stays. The objective of this study was to evaluate the prevalence of such errors in PD patients admitted to public acute-care hospitals in the Basque Country over a two year period and their association with clinically relevant adverse health outcomes, such as length of hospital stay and mortality...
December 31, 2016: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28063683/diphasic-dyskinesias-during-levodopa-carbidopa-intestinal-gel-lcig-infusion-in-parkinson-s-disease
#8
Meloni Mario, Solla Paolo, Mascia Mario Marcello, Marrosu Francesco, Cannas Antonino
OBJECTIVES: Levodopa-carbidopa intestinal gel infusion (LCIG) is indicated in patients with advanced levodopa-responsive Parkinson's disease (PD) for the treatment of motor fluctuations and dyskinesias. Here we describe 4 PD patients who developed disabling diphasic dyskinesias after LCIG initiation. METHODS: The clinical data of 33 PD patients consecutively treated with LCIG therapy were obtained through direct clinical observation and detailed review of medical records...
December 31, 2016: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28089265/gender-differences-in-parkinson-s-disease-depression
#9
Andrew J Perrin, Ekaterina Nosova, Kim Co, Adam Book, Oscar Iu, Vanessa Silva, Christina Thompson, Martin J McKeown, A Jon Stoessl, Matthew J Farrer, Silke Appel-Cresswell
INTRODUCTION: 30-40% of patients with Parkinson's disease (PD) experience depression during their illness; identifying subtypes of depression and groups at risk remains a challenge in routine clinical care. One avenue that remains underexplored is the gender-specific profiles manifested in PD depression. We sought to explore this in a large sample of clinical PD patients. METHODS: 307 patient records at a tertiary referral centre were reviewed for clinical and demographic factors...
December 29, 2016: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28082015/response-shift-the-experience-of-disease-progression-in-parkinson-disease
#10
Jessica Yang, Brenda Hanna-Pladdy, Ann L Gruber-Baldini, Erik Barr, Rainer von Coelln, Melissa J Armstrong, Stephen G Reich, Lisa M Shulman
OBJECTIVE: To investigate response shift, the recalibration of perceived quality of life (QoL) relative to symptomatic changes in Parkinson disease (PD). BACKGROUND: Health-related QoL in PD is influenced by improvement vs. decline in disease severity. However, it is unclear how disease course changes internal standards of QoL over time. METHODS: 124 PD patients were subdivided based on Total UPDRS change over 1 year (stable, improved, declined)...
December 29, 2016: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28057432/pattern-of-cognitive-impairment-in-patients-with-parkinson-s-disease-and-psychosis-a-critical-review
#11
REVIEW
Abhishek Lenka, Shantala Hegde, Shyam Sundar Arumugham, Pramod Kumar Pal
Psychosis is one of the debilitating non-motor symptoms (NMS) of Parkinson's disease (PD). Cognitive impairment is considered to be a risk factor for emergence of psychosis in PD. Early detection of relevant cognitive impairment may serve as a predictor for development of psychosis, with implications for prevention and early intervention. However, the exact pattern of cognitive impairment associated with psychosis is not clear. In this article, we aim to critically review the literature on case-control studies in PD patients with and without psychosis in order to understand the pattern of cognitive impairment in those with psychosis...
December 29, 2016: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28049603/dyskinesia-hyperpyrexia-syndrome-under-continuous-dopaminergic-stimulation
#12
LETTER
Fernando Acebrón Sánchez-Herrera, Nuria García-Barragán, Carlos Estévez-Fraga, Juan Carlos Martínez-Castrillo, Jose Luis López-Sendón Moreno
No abstract text is available yet for this article.
December 29, 2016: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28057431/advanced-structural-neuroimaging-in-progressive-supranuclear-palsy-where-do-we-stand
#13
REVIEW
Albert Stezin, Abhishek Lenka, Ketan Jhunjhunwala, Jitender Saini, Pramod K Pal
Progressive supranuclear palsy (PSP) is a progressive neurological disorder characterized by presence of supranuclear gaze palsy, early postural instability, parkinsonism and cognitive impairment. Advanced structural neuroimaging studies have demonstrated variable areas of grey and white matter involvement in PSP. Grey matter (GM) involvement is predominantly reported in the midbrain, subcortical structures such as thalamus and basal ganglia, and cerebellum. Most white matter (WM) tracts are also reported to be damaged in PSP...
December 26, 2016: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28089442/in-memoriam-felipe-pretelt-1951-2016
#14
EDITORIAL
Catalina Cerquera, Camilo Castañeda-Cardona
No abstract text is available yet for this article.
December 23, 2016: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28038867/parkinsonian-axial-signs-in-schizophrenia
#15
Francesca Morgante, Corrado Barbui, Michele Tinazzi
INTRODUCTION: We have recently demonstrated evidence of nigro-striatal denervation, disease progression and response to levodopa in a subgroup of patients with schizophrenia who developed parkinsonism. OBJECTIVE: In the present study, we investigated whether axial parkinsonian signs might be an early manifestation of parkinsonism in schizophrenia not necessarily related to chronic administration of antipsychotic drugs (AP) drugs. METHODS: From a baseline cohort of 299 schizophrenic patients who did not satisfy the diagnostic criteria for parkinsonism (presence of at least two of the following appendicular signs: bradykinesia, tremor, rigidity), we identified a group of patients who manifested two out of three axial parkinsonian signs (abnormality of trunk posture, hypomimia and short-step gait)...
December 23, 2016: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28038866/genetic-analysis-of-the-tmem230-gene-in-chinese-patients-with-familial-parkinson-disease
#16
LETTER
Hongwei Wu, Xiaosheng Zheng, Zhidong Cen, Fei Xie, You Chen, Xingjiao Lu, Wei Luo
No abstract text is available yet for this article.
December 22, 2016: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28027851/spatial-learning-deficits-in-parkinson-s-disease-with-and-without-mild-cognitive-impairment
#17
Christine B Schneider, Katharina Linse, Robby Schönfeld, Sebastian Brown, Rainer Koch, Heinz Reichmann, Bernd Leplow, Alexander Storch
BACKGROUND: Several MRI studies have demonstrated hippocampal atrophy in Parkinson's disease (PD), a structure considered a key element in spatial learning. Despite this, no study has been undertaken to investigate spatial navigation in PD using a virtual version of the Morris water maze, which is the gold standard for testing hippocampal function in rodents. METHODS: We studied 17 cognitively unimpaired PD patients, 12 PD patients with mild cognitive impairment (MCI) and 15 controls in a virtual water maze procedure...
December 22, 2016: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28024710/basal-ganglia-calcification-in-a-case-of-pkan
#18
LETTER
Alfonso Fasano, Gholamali Shahidi, Anthony E Lang, Mohammad Rohani
No abstract text is available yet for this article.
December 21, 2016: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28024709/thalamic-deep-brain-stimulation-as-rescue-therapy-for-tremor-following-bilateral-radiosurgery
#19
LETTER
Jonathan T Butler, William Rodriguez, Srivatsan Pallavaram, Peter Konrad, Christopher M Tolleson
No abstract text is available yet for this article.
December 21, 2016: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28017548/evaluating-the-role-of-tmem230-variants-in-parkinson-s-disease
#20
LETTER
Hauke Baumann, Simone Wolff, Alexander Münchau, Johann M Hagenah, Katja Lohmann, Christine Klein
No abstract text is available yet for this article.
December 20, 2016: Parkinsonism & related Disorders
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