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Continuum: Lifelong Learning in Neurology

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https://www.readbyqxmd.com/read/29200126/patient-management-problem-preferred-responses
#1
Raymond Price, Amy A Pruitt
No abstract text is available yet for this article.
December 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/29200125/patient-management-problem
#2
Raymond Price, Amy A Pruitt
No abstract text is available yet for this article.
December 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/29200121/appendix-b-useful-websites-for-oncology-patients-and-providers
#3
Amy A Pruitt
No abstract text is available yet for this article.
December 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/29200120/appendix-a-an-oncologic-reference-for-neurologists
#4
Amy A Pruitt
No abstract text is available yet for this article.
December 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/29200119/pediatric-brain-tumors
#5
Mai Dang, Peter C Phillips
PURPOSE OF REVIEW: This article describes the most common pediatric brain tumors and highlights recent developments in their diagnosis and treatment strategies. RECENT FINDINGS: We are in the midst of a molecular era for pediatric brain tumors. Genetic and epigenetic profiling of tumors has impacted their diagnosis, allowing for the subgrouping of heterogeneous tumor groups and leading to the complete renaming of some tumor types. These advances are reflected in the new 2016 World Health Organization classification...
December 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/29200118/palliative-care-end-of-life-care-and-advance-care-planning-in-neuro-oncology
#6
Tobias Walbert
PURPOSE OF REVIEW: Despite new therapeutic approaches, most patients with high-grade glioma face limited overall survival and have a high symptom burden throughout their disease trajectory, especially in the end-of-life phase. This article provides an overview of the role of palliative care in neuro-oncology. Management recommendations are made for neurologic symptoms in patients with advanced brain tumors, including headaches, nausea, and fatigue. Special attention is given to how and when to involve subspecialty palliative care and hospice services to improve symptom management during active tumor treatment and in the end-of-life phase of patients with brain tumors...
December 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/29200117/common-histologically-benign-tumors-of-the-brain
#7
Roy E Strowd, Jaishri O Blakeley
PURPOSE OF REVIEW: As a group, benign tumors account for the majority of primary neoplasms affecting the central nervous system (CNS). This article reviews the epidemiology, clinical presentation, neuroimaging features, and management of the most common of these tumors: meningiomas, schwannomas, and pituitary adenomas. RECENT FINDINGS: Awareness of the most common nonmalignant tumors of the CNS and their management guidelines is important as many of these tumors are managed conservatively, with neurologists playing a primary role in both surveillance and symptom management...
December 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/29200116/paraneoplastic-disorders
#8
Eric Lancaster
PURPOSE OF REVIEW: Paraneoplastic neurologic syndromes target specific areas of the nervous system with pathogenic autoantibodies or T-cell responses. Each syndrome conveys a risk of particular tumors. Expanded paraneoplastic antibody testing has led to improved diagnosis but created challenges involving appropriate interpretation of test results. RECENT FINDINGS: Peripheral nervous system paraneoplastic disorders such as myasthenia gravis and Lambert-Eaton myasthenic syndrome involve pathogenic autoantibodies...
December 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/29200115/medical-complications-of-brain-tumors
#9
Nimish A Mohile
PURPOSE OF REVIEW: This article discusses common and emergent medical complications encountered in patients with primary brain tumors. RECENT FINDINGS: Clinical studies and systematic reviews published in recent years have improved knowledge regarding the incidence of neurologic and medical complications occurring in patients with primary brain tumors. Studies in tumor-related epilepsy and venous thromboembolism provide data for the clinician to make evidence-based decisions about perioperative management, prophylaxis, and therapy...
December 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/29200114/neuroradiologic-pearls-for-neuro-oncology
#10
Joshua P Klein, Jorg Dietrich
PURPOSE OF REVIEW: This article reviews key principles in the identification of tumors of the central nervous system (CNS) using standard and advanced imaging modalities. This article highlights the pitfalls and pearls of the imaging evaluation of patients with cancer at time of diagnosis and during cancer therapy and discusses the challenges of the imaging evaluation of treatment-related toxicities. RECENT FINDINGS: Treatment of CNS tumors with surgery, chemotherapy, or radiation alters the imaging appearance of the tumor and can be associated with a variety of treatment-related toxicities...
December 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/29200113/primary-central-nervous-system-lymphoma
#11
Catherine H Han, Tracy T Batchelor
PURPOSE OF REVIEW: Primary central nervous system (CNS) lymphoma is a rare and aggressive extranodal non-Hodgkin lymphoma confined to the brain, eyes, spinal cord, or leptomeninges without systemic involvement. This article provides an overview of the clinical features, diagnosis, and management of primary CNS lymphoma in patients who are immunocompetent, focusing on recent advances in treatment. RECENT FINDINGS: Primary CNS lymphoma is sensitive to radiation therapy; however, whole-brain radiation therapy inadequately controls the disease when used alone and causes delayed neurotoxicity with significant neurocognitive impairment, especially in patients who are elderly...
December 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/29200112/epidemiology-treatment-and-complications-of-central-nervous-system-metastases
#12
Amy A Pruitt
PURPOSE OF REVIEW: Neurologic problems resulting from systemic cancer metastases to brain parenchyma, dura, spinal cord, and leptomeninges are among the most common types of consultations addressed by neurologists. With patients surviving longer from systemic cancer, along with the rapidly evolving therapeutic options, the treatment of these devastating complications has become both more effective and more complicated. This article reviews current patterns of metastatic disease and the increasingly nuanced landscape of evolving therapies, their complications, and their impact on quality of survival...
December 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/29200111/low-grade-gliomas
#13
David Schiff
PURPOSE OF REVIEW: Low-grade gliomas present vexing management issues for neuro-oncologists. The relatively long survival compared to other brain tumors makes consideration of treatment toxicity, and thus timing of potentially damaging interventions such as surgery, radiation, and chemotherapy, crucial. Moreover, the rarity of these tumors makes clinical trials to ascertain optimal care challenging. RECENT FINDINGS: The discovery that most low-grade gliomas harbor isocitrate dehydrogenase (IDH) mutations that confer a favorable prognosis has improved diagnosis and risk stratification of these tumors...
December 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/29200110/high-grade-gliomas
#14
Lakshmi Nayak, David A Reardon
PURPOSE OF REVIEW: This article reviews the standard treatment for high-grade gliomas, with a focus on promising new strategies and response assessment. RECENT FINDINGS: The new World Health Organization (WHO) classification of central nervous system tumors classifies high-grade gliomas based on molecular markers that are of prognostic and therapeutic significance. The addition of chemotherapy, specifically procarbazine, CCNU (lomustine), and vincristine, to radiation in newly diagnosed 1p/19q codeleted anaplastic oligodendrogliomas doubled overall survival...
December 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/29200109/2016-world-health-organization-classification-of-central-nervous-system-tumors
#15
Patrick Y Wen, Jason T Huse
PURPOSE OF REVIEW: Since 1979, the World Health Organization (WHO) has periodically published a consensus classification and grading of tumors of the central nervous system (CNS) to ensure uniform histopathologic diagnostic criteria worldwide. In 2016, the WHO published an update of the fourth edition of the classification of CNS tumors. This article summarizes the major changes in the update and discusses their impact on clinical practice. RECENT FINDINGS: For the first time, the 2016 revision of the WHO classification uses molecular parameters in addition to traditional histology to diagnose many CNS tumors, resulting in major restructuring of the classification of many tumors, especially gliomas, ependymomas, and medulloblastomas...
December 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/29200108/oncology-recapitulates-neurology
#16
EDITORIAL
Steven L Lewis
No abstract text is available yet for this article.
December 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/29200104/issue-overview
#17
(no author information available yet)
No abstract text is available yet for this article.
December 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28968377/patient-management-problem-preferred-responses
#18
Nimish J Thakore
No abstract text is available yet for this article.
October 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28968376/patient-management-problem
#19
Nimish J Thakore
No abstract text is available yet for this article.
October 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28968372/the-implication-of-diagnostic-errors
#20
Raghav Govindarajan
Diagnostic errors are mistakes in the diagnostic process that lead to a misdiagnosis, a missed diagnosis, or a delayed diagnosis. While the past decade's impetus to improve patient safety has focused on medication errors, health care-associated infections, and postsurgical complications, diagnostic errors have received comparatively less attention. Diagnostic errors will continue to play a major role in the patient safety and quality improvement movement because of their burden on care and their financial burden...
October 2017: Continuum: Lifelong Learning in Neurology
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