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Continuum: Lifelong Learning in Neurology

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https://www.readbyqxmd.com/read/28968377/patient-management-problem-preferred-responses
#1
Nimish J Thakore
No abstract text is available yet for this article.
October 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28968376/patient-management-problem
#2
Nimish J Thakore
No abstract text is available yet for this article.
October 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28968372/the-implication-of-diagnostic-errors
#3
Raghav Govindarajan
Diagnostic errors are mistakes in the diagnostic process that lead to a misdiagnosis, a missed diagnosis, or a delayed diagnosis. While the past decade's impetus to improve patient safety has focused on medication errors, health care-associated infections, and postsurgical complications, diagnostic errors have received comparatively less attention. Diagnostic errors will continue to play a major role in the patient safety and quality improvement movement because of their burden on care and their financial burden...
October 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28968371/right-to-try-investigational-therapies-for-incurable-disorders
#4
Zachary Simmons
Patients with life-threatening disorders such as amyotrophic lateral sclerosis, for which only minimally effective medical therapies currently exist, often seek treatments not proven to be effective and not approved by regulatory agencies for use outside of experimental treatment trials. The expanded access (compassionate use) provisions of the US Food and Drug Administration (FDA) for access to such therapies are often perceived as being inadequate. In response, states have passed right-to-try laws designed to improve access to experimental therapies for patients willing to assume the risks associated with such treatments...
October 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28968370/peripheral-nerve-hyperexcitability-syndromes
#5
Komal Sawlani, Bashar Katirji
PURPOSE OF REVIEW: This article provides a review of the clinical phenotypes and evaluation of peripheral nerve hyperexcitability syndromes. These rare diagnoses include cramp-fasciculation syndrome, Isaacs syndrome, and Morvan syndrome. Recent investigations have led to an understanding of the autoimmune underpinnings of these conditions and their specific associated antibodies. As the presentation of peripheral nerve hyperexcitability syndromes includes muscle stiffness, twitches, and spasms, which are also shared with certain central nervous system and myopathic conditions, the differential diagnosis of peripheral nerve hyperexcitability syndromes is reviewed...
October 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28968369/sensory-polyneuropathies
#6
Kelly Graham Gwathmey
PURPOSE OF REVIEW: This article describes the methods of diagnosis and management of the sensory-predominant polyneuropathies. To simplify the approach to this category of patients, sensory-predominant polyneuropathies are divided broadly into either small fiber (or pain-predominant) neuropathies and large fiber (or ataxia-predominant) neuropathies, of which the sensory neuronopathies (dorsal root ganglionopathies) are highlighted. RECENT FINDINGS: Physicians can now easily perform skin biopsies in their offices, allowing access to the gold standard pathologic diagnostic tool for small fiber neuropathies...
October 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28968368/immune-axonal-polyneuropathy
#7
Jinny O Tavee
PURPOSE OF REVIEW: Immune axonal polyneuropathy is caused by a diverse group of disorders that share similar presentations and treatment regimens. This article focuses on the clinical findings, evaluation, and management of immune-mediated causes of axonal polyneuropathy, focusing primarily on large fiber sensorimotor polyneuropathy. RECENT FINDINGS: Specific characteristics of an immune-mediated polyneuropathy have been incorporated in a new diagnostic screening tool that is highly sensitive and can easily be used in the outpatient clinic setting...
October 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28968367/axonal-sensorimotor-polyneuropathies
#8
Yuebing Li
PURPOSE OF REVIEW: This article describes clinical features of axonal sensorimotor polyneuropathies based on selected etiologies. RECENT FINDINGS: Axonal sensorimotor polyneuropathies have been well described for some time. Recent advances include the assessment of the incidence of peripheral neuropathy in the elderly, the recognition of the limited influence of electrodiagnostic testing on the clinical management of uncomplicated axonal sensorimotor polyneuropathy, the development of guidelines for treatment of painful neuropathy, the identification of risk factors predisposing patients for chemotherapy-induced neuropathy, a report on the association of metabolic syndrome and idiopathic axonal sensorimotor neuropathy, and the availability of more cost-effective genetic testing for identifying inherited polyneuropathies...
October 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28968366/charcot-marie-tooth-disease-and-other-genetic-polyneuropathies
#9
Sindhu Ramchandren
PURPOSE OF REVIEW: Genetic polyneuropathies are rare and clinically heterogeneous. This article provides an overview of the clinical features, neurologic and electrodiagnostic findings, and management strategies for Charcot-Marie-Tooth disease and other genetic polyneuropathies as well as an algorithm for genetic testing. RECENT FINDINGS: In the past 10 years, many of the mutations causing genetic polyneuropathies have been identified. International collaborations have led to the development of consortiums that are undertaking careful genotype-phenotype correlations to facilitate the development of targeted therapies and validation of outcome measures for future clinical trials...
October 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28968365/diagnosis-and-clinical-management-of-amyotrophic-lateral-sclerosis-and-other-motor-neuron-disorders
#10
Stephen A Goutman
PURPOSE OF REVIEW: This article reviews the clinical features, diagnostic pathway, therapies, and current understanding of the pathophysiology of amyotrophic lateral sclerosis (ALS). The spectrum of motor neuron diseases is reviewed, and the clinical heterogeneity of ALS is described. RECENT FINDINGS: ALS is increasingly recognized as a clinical spectrum disorder with pure upper and pure lower motor neuron presentations, supported by genetic links. The phenotypic variability is broad...
October 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28968364/chronic-demyelinating-polyneuropathies
#11
Jeffrey A Allen
PURPOSE OF REVIEW: This article reviews the chronic demyelinating neuropathies, with a focus on the diagnosis and treatment of immune-mediated neuropathies and the features that can help differentiate immune-mediated neuropathies from other chronic demyelinating peripheral nerve conditions. RECENT FINDINGS: Advances in clinical phenotyping and outcomes assessment have enabled neurologists to improve disease recognition, treatment, and disease monitoring. Our understanding of the immunopathogenesis of demyelinating neuropathies is evolving...
October 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28968363/guillain-barr%C3%A3-syndrome
#12
Peter D Donofrio
PURPOSE OF REVIEW: This article reviews the current state of Guillain-Barré syndrome (GBS), including its clinical presentation, evaluation, pathophysiology, and treatment. RECENT FINDINGS: GBS is an acute/subacute-onset polyradiculoneuropathy typically presenting with sensory symptoms and weakness over several days, often leading to quadriparesis. Approximately 70% of patients report a recent preceding upper or lower respiratory tract infection or gastrointestinal illness...
October 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28968362/ultrasonography-in-peripheral-nervous-system-diagnosis
#13
Francis O Walker
PURPOSE OF REVIEW: High-resolution ultrasound has made it possible to view most nerves and muscles in real time and to identify pathologic change in size, echo texture, and vascularity. This article focuses on the principles underlying ultrasound imaging and the application of ultrasound imaging to clinical disorders commonly seen in an electrodiagnostic laboratory. RECENT FINDINGS: Ultrasound is a sensitive and specific tool for evaluating myopathic and neurogenic muscle disease...
October 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28968361/neurophysiologic-studies-in-the-evaluation-of-polyneuropathy
#14
John C Kincaid
PURPOSE OF REVIEW: This article provides core information on the clinical neurophysiology techniques available for the investigation of disorders of the peripheral nervous system. RECENT FINDINGS: The role of small fiber dysfunction in some types of polyneuropathy is being increasingly appreciated, and neurophysiologic techniques for evaluating the autonomic components of peripheral axons have enhanced our understanding of small fiber dysfunction. SUMMARY: The principles of nerve conduction studies and needle EMG are presented in this article, along with the patterns of abnormality encountered in patients with polyneuropathy due to large and small fiber involvement...
October 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28968360/general-approach-to-peripheral-nerve-disorders
#15
James A Russell
PURPOSE OF REVIEW: This article provides a conceptual framework for the evaluation of patients with suspected polyneuropathy to enhance the clinician's ability to localize and confirm peripheral nervous system pathology and, when possible, identify an etiologic diagnosis through use of rational clinical and judicious testing strategies. RECENT FINDINGS: Although these strategies are largely time-honored, recent insights pertaining to the pathophysiology of certain immune-mediated neuropathies and to evolving genetic testing strategies may modify the way that select causes of neuropathy are conceptualized, evaluated, and managed...
October 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28968359/the-periphery-at-the-center
#16
Steven L Lewis
No abstract text is available yet for this article.
October 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28777189/patient-management-problem-preferred-responses
#17
Erik K St Louis
No abstract text is available yet for this article.
August 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28777188/patient-management-problem
#18
Erik K St Louis
No abstract text is available yet for this article.
August 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28777184/appendix-epworth-sleepiness-scale
#19
(no author information available yet)
No abstract text is available yet for this article.
August 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28777183/sleep-medicine-coding-and-coverage-guidelines
#20
Waleed Hamed El-Feky, David A Evans
Successful sleep billing and reimbursement is dependent on correct reporting of proper diagnostic codes for sleep disorders and associated testing. Recent changes in disease classification systems have affected the coding for sleep disorders. Guidelines set forth by the American Academy of Sleep Medicine and followed by third-party payers provide direction for the required techniques and indications for sleep procedures.
August 2017: Continuum: Lifelong Learning in Neurology
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