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Oral Diseases

Önder Gürlek, Pınar Gümüş, Nurcan Buduneli
AIM: To comparatively evaluate peri-implant health status in smokers and non-smokers. MATERIALS AND METHODS: A total of 142 implants (74 implants in non-smokers, 68 in smokers) in 43 smoker or non-smoker systemically healthy patients were included in the study. Demographic and clinical periodontal data were recorded and analysed by Chi-square and Mann-Whitney U tests. RESULTS: Peri-implantitis and mucositis cases were significantly more frequent in the smokers than non-smokers (p=0...
August 11, 2017: Oral Diseases
Alpdogan Kantarci, Hatice Hasturk
The human body hosts billions of microorganisms. According to one estimate, the ratio of bacterial cells to human cells is 10:1. There are an enormous diversity and specificity based on where the species live and how they interact with each other as well as the host. While bacterial species define how the host lives and adapts to its environment, host-associated factors also determine the microbiome and its components. This article is protected by copyright. All rights reserved.
August 11, 2017: Oral Diseases
Qiao Shi Xu, Chong Wang, Bo Li, Jin Zhong Li, Ming Hui Mao, Li Zheng Qin, Hua Li, Xin Huang, Zhengxue Han, Zhien Feng
OBJECTIVE: The purposes of this study were to explore both the prognostic value of pathologic grade and the relationships between differentiation and clinicopathological characteristics in oral squamous cell carcinoma. METHODS: This retrospective cohort study included the records of 2036 patients with oral squamous cell carcinoma who were surgically treated from June 1999 to December 2011. Chi square test, Kaplan-Meier analysis and Cox proportional-hazards regression model were performed for statistical analysis...
August 8, 2017: Oral Diseases
Paswach Wiriyakijja, Stefano Fedele, Stephen Porter, Valeria Mercadante, Richeal Ni Riordain
OBJECTIVES: To analyse the range of existing patient-reported outcome measures (PROMs) used in studies of recurrent aphthous stomatitis (RAS) and to evaluate their quality properties via the assessment of psychometric properties and interpretability. MATERIALS AND METHODS: Electronic databases were searched to identify relevant publications related to PROMs used in RAS. Publications were selected based on predefined criteria. All identified PROMs were then classified by measuring concepts and assessed for instrument characteristics and evidence for quality properties for RAS patients...
August 5, 2017: Oral Diseases
J M Trevillyan, J J Chang, J S Currier
We read with great interest your special edition 'The Mouth and AIDS' (Vol 22, Supplement S1, April 2016) which highlighted the important and oft ignored issue of oral health in people living with HIV. Oral disease appears common in the setting of HIV, with rates of chronic periodontitis reported to be as high as 76% in HIV-positive individuals (Kroidl, Schaeben, Oette et al., 2005), This article is protected by copyright. All rights reserved.
August 5, 2017: Oral Diseases
Rym Kammoun, Catherine Behets, Lamia Mansour, Sonia Ghoul-Mazgar
To explore the mineral features of dentin and cementum in hypoplastic AI teeth MATERIALS AND METHODS: Forty four (44) teeth cleaned and free of caries were used: 20 control and 24 affected by hypoplastic amelogenesis imperfecta. Thirty-two teeth were studied by pQCT, cut in sections and analysed under microradiography, polarized light microscopy and confocal Raman spectroscopy. Eight teeth were observed under scanning electron microscope. Four teeth were used for an X-ray diffraction. The mineral density data were analysed statistically with the Mann-Whitney U test, using GraphPad InStat Software RESULTS: Both coronal and radicular dentin were less mineralized in AI teeth when compared to control (respectively 6...
August 3, 2017: Oral Diseases
Jiao Li, XiaoJing Ke, Fuhua Yan, Lang Lei, Houxuan Li
Periodontal tissues are constantly exposed to microbial stimuli. The equilibrium between microbes and host defense system helps maintain the homeostasis in the periodontal microenvironment. Growth of pathogenic bacteria in dental biofilms may induce proinflammatory cytokine production to recruit sentinel cells, mainly neutrophils and monocytes into the gingival sulcus or the periodontal pocket. Moreover,dybiosis with over-growth of anaerobic pathogens, such as Porphyromonas gingivalis and Tannerella forsythia, may induce death of both immune cells and host resident cells...
August 1, 2017: Oral Diseases
Goli Chamani, Mohammad Reza Shakibi, Mohammad Reza Zarei, Maryam Rad, Adeleh Pouyafard, Ardavan Parhizkar, Mojdeh Mansoori
OBJECTIVE: To determine the relationship between xerostomia and Oral-Health Related Quality of Life in patients with rheumatoid arthritis. MATERIALS AND METHODS: Two hundred patients with rheumatoid arthritis were assessed using Fox and OHIP-14 questionnaires concerning xerostomia and Oral-Health Related Quality of Life respectively. The sum of decayed, missing and filled teeth (DMFT) was determined via an intra-oral exam. In addition, intergroup comparisons were evaluated using T-test, Chi-square, regression and Tukey analysis...
July 27, 2017: Oral Diseases
Nimisha Divakar
In a recently published study "Topical tocopherol for treatment of reticular oral lichen planus: a randomized, double-blind, crossover study" (Oral Diseases, January 2017), the authors have assessed the efficacy of topical tocopherol acetate in improving the lesions and oral discomfort of patient's suffering from reticular oral lichen planus comparing it with the results achievable by administering placebo. ((1)) In the study, 34 patients with clinically diagnosed and histologically confirmed ROLP were randomly assigned to two groups, which received first one of two treatments (treatment 1 or 2) for a month, then the other (treatment 2 or 1) for another month, with a two-week washout between them...
July 26, 2017: Oral Diseases
Bruno Ramos Chrcanovic, Ricardo Santiago Gomez
OBJECTIVE: To integrate the available data published on glandular odontogenic cyst (GOC) into a comprehensive analysis of its clinical/radiologic and histopathological features. METHODS: An electronic search was undertaken in May/2017. Eligibility criteria included publications having enough clinical/radiological/histological information to confirm the diagnosis. RESULTS: 58 publications (169 GOCs) were included. The lesion was slightly more prevalent in men than in women...
July 26, 2017: Oral Diseases
Luiz Alcino Gueiros, Telma Arão, Thayse Souza, Camila Lins Vieira, Ricardo Santiago Gomez, Oslei Paes de Almeida, Giovani Lodi, Jair Carneiro Leão
OBJECTIVE: The aim of this study was to evaluate the association of IL-17A G197A polymorphism and serum levels with oral lichen planus susceptibility and clinical presentation. SUBJECTS AND METHODS: Eighty three individuals diagnosed with oral lichen planus (OLP) and ninety nine healthy controls (C) were consecutively recruited. All participants had desquamating oral mucosal cells collected and DNA isolated for IL-17A (G197A) genotyping. Blood samples of 42 OLP individuals and 23 healthy controls were collected for evaluation of IL-17A serum levels...
July 25, 2017: Oral Diseases
Jinli Liu, Fangman Chen, Zihao Wei, Min Qiu, Zheru Li, Hongxia Dan, Qianming Chen, Lu Jiang
OBJECTIVES: Oral submucous fibrosis (OSMF), a potentially malignant oral cavity disorder that causes speech and mastication problems, lacks an established treatment regimen; moreover, no treatment can effectively reverse the course of OSMF. A meta-analysis was conducted to investigate the efficacy of the peripheral vasodilator, pentoxifylline, in the treatment of OSMF. METHODS: We searched five different databases for studies meeting our eligibility criteria (up to June 30, 2017)...
July 24, 2017: Oral Diseases
Zihao Wei, Qianqian Hou, Heng Xu, Lu Jiang, Qianming Chen
The study by Wu et al (2014), which examined the association between mtDNA haplogroups and oral lichen planus (OLP) susceptibility, identified a protective role of mitochondrial haplogroup B4 in OLP susceptibility in Chinese individuals. This study points to the importance of genetic factors in OLP pathogenesis. To date, only a limited number of studies (especially case studies) have provided evidence for the role of genetic predisposition in OLP pathogenesis. This article is protected by copyright. All rights reserved...
July 24, 2017: Oral Diseases
K Delli, C Livas, F K L Spijkervet, A Vissink
OBJECTIVES: To identify the most discussed dental articles on the Web and to assess the association between the intensity of online attention, publication characteristics and citations. MATERIALS & METHODS: An Altmetric Explorer search was conducted for articles published in the 91 dental journals included in 2015 InCites(™) Journal Citation Report(®) and mentioned online at all times. The 100 articles with the highest online attention, as measured by the 'Altmetric Attention Score' (AAS), were screened for journal title, quartile of impact factor distribution (Q1-Q4), publication date, origin and affiliation of first author, article topic, type and access...
July 22, 2017: Oral Diseases
D Listyarifah, A Al-Samadi, A Salem, A Syaify, T Salo, T Tervahartiala, D Grenier, D C Nordström, T Sorsa, M Ainola
OBJECTIVE: Evidence of increased apoptosis is observed in periodontitis and may be associated with destruction of the periodontal tissue caused by the increased cell death, with the release of danger signals and subsequent stimulation of the proinflammatory processes. However, the exact mechanisms associated with these processes remain unclear. This study aimed to investigate the presence of the periodontal pathogen Treponema denticola, apoptosis, high mobility group box 1 as a damage-associated molecular pattern, and several inflammatory markers in periodontitis and gingivitis subjects...
July 7, 2017: Oral Diseases
R V Lalla, N Treister, T Sollecito, B Schmidt, L L Patton, K Mohammadi, J S Hodges, M T Brennan
OBJECTIVE: To examine oral complications 6 months after modern radiation therapy (RT) for head and neck cancer (HNC). METHODS: Prospective multicenter cohort study of patients with HNC receiving intensity-modulated radiation therapy or more advanced RT. Stimulated whole salivary flow, maximal mouth opening, oral mucositis, oral pain, oral health-related quality of life (OH-QOL), and oral hygiene practices were measured in 372 subjects pre-RT and 216 subjects at 6 months from the start of RT...
July 4, 2017: Oral Diseases
Kelly McGowan, Troy McGowan, Saso Ivanovski
OBJECTIVE: The purpose of this study was to identify the patient populations at risk of medication related osteonecrosis of the jaw (MRONJ) and determine which medical and dental comorbidities are significant risk factors for this disease. METHODS: An electronic search of Embase, MEDLINE, Cochrane Central Register of Controlled Trials, WHO International Clinical Trials Registry Platform and ProQuest Dissertations and Theses Global was conducted to identify all human studies that reported risk factors for MRONJ...
June 28, 2017: Oral Diseases
Camila Nobre de Freitas, Paula Midori Castelo, Karina Guedes de Sousa, Gabriela Caroline Alonso, Fernando Luiz Affonso Fonseca, Marlise Inês Klein, Taís de Souza Barbosa
OBJECTIVE: To evaluate educational strategies and ART-restoration impact on salivary physicochemical and microbiological characteristics. DESIGN: Two groups of 6-7-yr-old children were included: GART , with at least one decayed primary molar (n=36), submitted to 4 sessions of oral health educational strategy (OHES) and ART-restoration; GC , a paired caries-free group (n=36), submitted to 4 sessions of OHES. Three evaluations were carried out: baseline, one week after OHES and one month after OHES or ART, when biofilm and gingivitis frequencies, salivary flow, pH, buffer capacity, calcium and phosphorus concentrations were assessed...
June 26, 2017: Oral Diseases
Marilia A Figueiredo, Maria Cristina Domingues Fink, Talita Castro, Paulo Henrique Braz-Silva, Jeanne Carla Steffens, Fernanda de Paula Eduardo, Marina Gallottini, Karem L Ortega
OBJECTIVE: This study aimed to identify and quantify polyomaviruses (BKPyV and JCPyV) in the saliva, mouthwash, blood and urine of liver pre-transplant patients. MATERIALS & METHODS: A case-control study was performed using a convenience sample of 21 end-stage liver disease patients (EG = experimental group) and 20 normoreactive controls (CG = control group). In total, 162 samples were collected. Detection and quantification of polyomaviruses were performed by using real-time PCR method...
June 26, 2017: Oral Diseases
R A Machado, H A R Pontes, F R Pires, H M Silveira, A Bufalino, R Carlos, F M Tuji, D B M Alves, A R Santos-Silva, M A Lopes, H M Capistrano, R D Coletta, F P Fonseca
OBJECTIVE: To describe the clinical and genetic features of patients with cherubism. MATERIAL AND METHODS: A descriptive analysis of 14 cases from 9 different families was carried out. Clinicopathological, imaging and follow-up data were retrieved from patients' medical files and correlated with the genetic profile of each patient. Genomic DNA isolated from buccal mucosa cells was subjected to direct sequencing analysis of the SH3BP2 gene. RESULTS: Females were more affected than males (8:6), and the mean age at diagnosis was 8...
June 23, 2017: Oral Diseases
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