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Journal of Trace Elements in Medicine and Biology

B Sundararajan, B D Ranjitha Kumari
The Aedes aegypti L. mosquito transmits dengue and yellow fever, which cause millions of death every year. Dengue is a mosquito-borne viral disease that has rapidly spread worldwide particularly in countries with tropical and subtropical climates areas. The present study denotes a simple and eco-friendly biosynthesis of gold nanoparticles using Artemisia vulgaris L. leaf extract as reducing agent. The synthesized gold nanoparticles were characterized by UV-Visible Spectroscopy, X-Ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FT-IR), Dynamic Light Scattering (DLS), Zeta Potential (ZP), Transmission Electron Microscopy (TEM) and Energy Dispersive X-ray Spectroscopy (EDX)...
March 18, 2017: Journal of Trace Elements in Medicine and Biology
K Maduray, J Moodley, C Soobramoney, R Moodley, T Naicker
Pre-eclampsia is a hypertensive disorder that is associated with adverse maternal and perinatal outcomes. It has been proposed that specific trace and macro elements associated with antioxidant activities may also play a contributory role in aetiology of pre-eclampsia. The aim of this study was to measure the concentrations of thirteen different elements in hair and serum samples from women with a diagnosis of pre-eclampsia and compare them with normotensive controls. Venous blood and pubic hair samples were collected from forty-three pre-eclamptic and twenty-three normotensive pregnant women...
March 9, 2017: Journal of Trace Elements in Medicine and Biology
Emilio Carpenè, Giulia Andreani, Gloria Isani
The role of trace elements in animal health has attracted increasing interest in recent years. The essentiality and toxicity of these elements have been extensively investigated in humans, laboratory animal models and partially in domestic animals, whereas little is known about trace element metabolism in most living organisms. Forty years ago our research started on Cd metabolism in molluscs, thereafter expanding to Zn, Cu, and Fe metabolism in many unconventional animal species of veterinary interest. This review summarizes the main results obtained over this long period of time: some of the findings are original and have not been published to date...
February 10, 2017: Journal of Trace Elements in Medicine and Biology
Eleni Sazakli, Michalis Leotsinidis
An epidemiological cross-sectional study was conducted in a Greek population, being orally exposed to Ni via food consumption, in order to investigate possible health effects and to evaluate hair Ni concentration as a biomarker of exposure. The study population consisted of 139 men and 155 women, aged 25-69. Socio-demographics, lifestyle, dietary habits, occupational and medical history data were recorded through a personal interview. Hematological and biochemical examinations were conducted in blood specimens...
February 6, 2017: Journal of Trace Elements in Medicine and Biology
Miguel Chin Chan, Elizabeth Bautista, Isabel Alvarado-Cruz, Betzabet Quintanilla-Vega, José Segovia
Exposure to mercury (Hg) occurs through different pathways and forms including methylmecury (MeHg) from seafood and rice, ethylmercury (EtHg), and elemental Hg (Hg(0)) from dental amalgams and artisanal gold mining. Once in the brain all these forms are transformed to inorganic Hg (I-Hg), where it bioaccumulates and remains for long periods. Hg is a well-known neurotoxicant, with its most damaging effects reported during brain development, when cellular key events, such as cell differentiation take place. A considerable number of studies report an impairment of neuronal differentiation due to MeHg exposure, however the effects of I-Hg, an important form of Hg found in brain, have received less attention...
February 6, 2017: Journal of Trace Elements in Medicine and Biology
Jinyan Fu, Anqiang Yang, Jun Zhao, Yunlong Zhu, Ying Gu, Yaohui Xu, Daozhen Chen
Our objective was to evaluate the relationship between iron level and thyroid function during the first trimester of pregnancy in Eastern China. This was a hospital-based, cross-sectional observational study. A total of 1764 pregnant women were enrolled during their first trimester of gestation in Wuxi city. Serum ferritin (SF), hemoglobin (Hb), urinary iodine concentrations (UIC), thyroid-stimulating hormone (TSH), free thyroxine (FT4) and free triiodothyronine (FT3) were measured and evaluated in pregnant women...
January 22, 2017: Journal of Trace Elements in Medicine and Biology
Giuseppa Visalli, Alessio Facciolà, Daniela Iannazzo, Anna Piperno, Alessandro Pistone, Angela Di Pietro
This study aimed to investigate the role of iron, used as a catalyst, in the biological response to pristine and functionalized multi-walled carbon nanotubes (p/fMWCNTs) with an iron content of 2.5-2.8%. Preliminarily, we assessed the pro-oxidant activity of MWCNTs-associated iron by an abiotic test. To evaluate iron bioavailability, we measured intracellular redox-active iron in A549 cells exposed to both MWCNT suspensions and to the cell medium preconditioned by MWCNTs, in order to assess the iron dissolution rate under physiological conditions...
January 20, 2017: Journal of Trace Elements in Medicine and Biology
Alicia Moreno-Ortega, Rafael Moreno-Rojas, Jesús Román Martínez-Álvarez, Montserrat González Estecha, Numa Pompilio Castro González, Manuel Ángel Amaro López
In Spain, recently, the public institutions have given information to the population in relation to fish consumption and the risk that it poses to health from the ingestion of mercury supposedly contained in the fish. At the same time, several scientific societies have published various works in this direction. All this without there being, up to now, any study on the evaluation of a probabilistic risk from mercury due to fish and seafood intake in Spain, which is the objective of this present work. For that purpose, we took individual data from a survey of the total diet of 3000 people, whose consumption of the principal fish and seafood species (49) was estimated...
January 16, 2017: Journal of Trace Elements in Medicine and Biology
Anatoly V Skalny, Lydmila L Klimenko, Aliya A Turna, Maria N Budanova, Ivan S Baskakov, Marina S Savostina, Aksana N Mazilina, Anatoly I Deyev, Margarita G Skalnaya, Alexey A Tinkov
The objective of the present study was to assess hormonal and trace element status in men suffering from acute ischemic stroke. METHODS: 21 acute ischemic stroke patients and 21 age- and body mass index-matched healthy volunteers were enrolled in the study. Serum trace elements were assessed using inductively coupled plasma mass spectrometry. Serum hormones and brain damage markers were estimated using enzyme-linked immunosorbent assay. RESULTS: Ischemic stroke patients are characterized by significantly higher levels of total and free triiodothyronine (T3), anti-thyroid peroxidase antibodies (Anti-TPO-Ab), prolactin, and cortisol, whereas the level of thyroid stimulating hormone (TSH) was decreased...
January 6, 2017: Journal of Trace Elements in Medicine and Biology
Natalia A Platonova, Iurii A Orlov, Sergey A Klotchenko, Victor S Babich, Ekaterina Y Ilyechova, Polina S Babich, Yuri P Garmai, Andrey V Vasin, Nadezhda V Tsymbalenko, Liudmila V Puchkova
Copper metabolism disturbances in mammary gland (MG) cells have severe consequences in newborns. The mechanism that controls the balance of copper in the MG has not been thoroughly characterized. Four primary copper homeostasis genes in mammals: (1) ceruloplasmin (Cp) encoding multifunction multicopper blue (ferr)oxidase; (2) CTR1 encoding high affinity copper importer 1; and (3 and 4) two similar genes encoding Cu(I)/Cu(II)-ATPases P1 type (ATP7A and ATP7B) responsible for copper efflux from the cells and metallation of cuproenzymes formed in the Golgi complex are expressed in MG...
January 3, 2017: Journal of Trace Elements in Medicine and Biology
Marco Vinceti, Tommaso Filippini, Jessica Mandrioli, Federica Violi, Annalisa Bargellini, Jennifer Weuve, Nicola Fini, Peter Grill, Bernhard Michalke
Exposure to neurotoxic chemicals such as pesticides, selenium, and heavy metals have been suggested to play a role in the etiology of amyotrophic lateral sclerosis (ALS). We assessed exposure to lead, cadmium, and mercury in 38 ALS patients (16 men and 22 females) and 38 hospital-admitted controls by using their cerebrospinal fluid (CSF) content as biomarker. We determined CSF heavy metal levels with inductively coupled plasma sector field mass spectrometry, according to a methodology specifically developed for this biological matrix...
January 3, 2017: Journal of Trace Elements in Medicine and Biology
Montserrat González-Estecha, Irene Palazón-Bru, Andrés Bodas-Pinedo, Elena Trasobares, Antonio Palazón-Bru, Manuel Fuentes, M Ángeles Cuadrado-Cenzual, Elpidio Calvo-Manuel
INTRODUCTION: Several studies have shown an inverse relationship between selenium status and cardiovascular health, although epidemiologic evidence yielded by the randomized trials did not find a beneficial effect of selenium administration. The aim of this study was to analyze the association between serum selenium levels and lipid profile adjusted by age, sex and other associated factors among a general adult population in Spain. MATERIALS AND METHODS: We recruited 372 hospital employee volunteers (60 men and 312 women) with a mean age of 47 (SD: 10...
January 3, 2017: Journal of Trace Elements in Medicine and Biology
David Clases, Marvin Birka, Michael Sperling, Andreas Faust, Uwe Karst
A novel quantification method named isobaric dilution analysis (IBDA) is introduced for internal calibration using inductively coupled plasma mass spectrometry (ICP-MS). Unlike isotope dilution analysis (IDA), where a sample to be analysed for a target analyte element is spiked with an isotopically enriched solution of the same element, IBDA uses the fact that conventional mass analysers cannot distinguish between two isobaric isotopes of different elements. Therefore, in IBDA, the sample with the element of interest is spiked with a solution of a different element, which shares at least one isobaric isotope and shows similar chemical properties resulting in a similar response...
March 2017: Journal of Trace Elements in Medicine and Biology
Hongmei Zhang, Chonghuai Yan, Zhen Yang, Weiwei Zhang, Yixin Niu, Xiaoyong Li, Li Qin, Qing Su
OBJECTIVE: The aim of the present study is to investigate the association of trace elements and the risk of type 2 diabetes mellitus. DESIGN AND METHODS: The 1837 participants (637 men and 1200 women) aged 40-70 were from a cross-sectional community-based study performed in downtown Shanghai. All the participants without diabetes mellitus history underwent a 75-g OGTT. The participants with diabetes mellitus took 100g steamed bread as the substitute. The fasting and OGTT 2h or postprandial 2h venous blood samples were collected...
March 2017: Journal of Trace Elements in Medicine and Biology
Guenievre Roussel, Valerie Stevens, Sarah Cottin, Harry J McArdle
Iron (Fe) metabolism is modified by many nutritional factors. Amino acids (AA) play a central role in various biological processes, such as protein synthesis and energy supply. However, the influence of AA status on iron metabolism has not been investigated. Here, we test whether AA alters iron metabolism in an intestinal cell model. Both Fe uptake and transfer across the cell monolayer were significantly increased by non-essential AA deficiency (both p<0.001) while only Fe transfer was increased by essential AA deficiency (p<0...
March 2017: Journal of Trace Elements in Medicine and Biology
Ekin Ö Tunçay, T Tolga Demirtaş, Menemşe Gümüşderelioğlu
The aim of the present study is to produce boron (B) doped hydroxyapatite (B-HAp), which has an osteoinductive property, and investigate in-vitro osteogenesis potential of B-HAp coated chitosan (B-HAp/Ch) scaffolds. At first, B-HAp was produced by the interaction of ions within the concentrated synthetic body fluid containing boron (B-SBF) with microwave energy. Boron incorporation into HAp structure was performed by the substitution of borate ions with phosphate and hydroxyl ions. Experiments were carried out with different microwave powers and exposure times, and optimum conditions for the production of B-HAp were determined...
March 2017: Journal of Trace Elements in Medicine and Biology
Renata Bandeira Lages, Enrico Coser Bridi, Carlos Alberto Pérez, Roberta Tarkany Basting
The purpose of this retrospective cohort study was to measure the salivary levels of nickel (Ni), chromium (Cr), iron (Fe) and copper (Cu) released from metal and esthetic fixed orthodontic appliances. Ninety patients were divided into three groups (n=30): control (those who had never undergone orthodontic treatment), metal appliance (stainless steel brackets and bands, and nitinol archwires) and esthetic appliance (polycarbonate brackets and tubes, and rhodium-coated nitinol archwires). Patients undergoing orthodontic treatment had used their appliances for periods between one and six months...
March 2017: Journal of Trace Elements in Medicine and Biology
Chang Xu, Yi Ding, Ho Wah Leung, Benny Meng Kiat Tong, Richard Y C Shin, Tong Kooi Lee
High accuracy methods were developed for the measurements of calcium, potassium, iron and magnesium in human serum using standard addition and isotope dilution mass spectrometry methods. The results were comparable to those obtained by other national metrology institutes and designated institutes as demonstrated in an inter-laboratory comparison. The methods were then adopted for the assignment of reference values in a human serum material and the uncertainties associated with the certified values were obtained by combining the uncertainty components from the characterisation, homogeneity and long-term stability of the materials...
March 2017: Journal of Trace Elements in Medicine and Biology
J I Lachowicz, S Palomba, P Meloni, M Carboni, G Sanna, R Floris, V Pusceddu, M Sarigu
In 1953, during the building restoration of San Michele church (Bono, Sardinia, 16th-19th Century), a high number of disarticulated skeletons were recovered. From a group of 412 hip bones, two of these, affected by several pathological lesions, were analysed. The two coxal bones can be referred to the same individual, an adult man. A multi-analytical study, started with the purpose of investigating the bone pathology, was extended to characterize the mineral components of a large representative set of bones from the same ossuary, all attributed to adult men who lived in the region four-two centuries ago...
March 2017: Journal of Trace Elements in Medicine and Biology
Ailin Falkmo Hansen, Anica Simić, Bjørn Olav Åsvold, Pål Richard Romundstad, Kristian Midthjell, Tore Syversen, Trond Peder Flaten
Differences in trace elements levels between individuals with type 2 diabetes and controls have been reported in several studies in various body fluids and tissues, but results have been inconsistent. In order to examine trace element levels in the early phase of type 2 diabetes, we investigated the association between whole blood levels of 26 trace elements and the prevalence of previously undiagnosed, screening-detected type 2 diabetes. The study was conducted as a case-control study nested within the third survey of the population-based Nord-Trøndelag Health Study (HUNT3 Survey)...
March 2017: Journal of Trace Elements in Medicine and Biology
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