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Journal of Atherosclerosis and Thrombosis

Ichiro Tatsuno
No abstract text is available yet for this article.
October 18, 2016: Journal of Atherosclerosis and Thrombosis
Yohei Shibata, Hideki Ishii, Susumu Suzuki, Akihito Tanaka, Yosuke Tatami, Shingo Harata, Tomoyuki Ota, Yusaku Shimbo, Yohei Takayama, Ayako Kunimura, Kenshi Hirayama, Kazuhiro Harada, Naohiro Osugi, Toyoaki Murohara
AIMS: Previous studies have shown that aortic valve calcification (AVC) was associated with cardiovascular events and mortality. On the other hand, periprocedural myocardial injury (PMI) in percutaneous coronary intervention (PCI) is a well-known predictor of subsequent mortality and poor clinical outcomes. The purpose of the study was to assess the hypothesis that the presence of AVC could predict PMI in PCI. METHODS: This study included 370 patients treated with PCI for stable angina pectoris...
October 13, 2016: Journal of Atherosclerosis and Thrombosis
Tatsuya Shiraki, Osamu Iida, Mitsuyoshi Takahara, Yoshimitsu Soga, Shinsuke Mii, Jin Okazaki, Sosei Kuma, Terutoshi Yamaoka, Daisuke Kamoi, Yoshiaki Shintani, Toshinobu Ishikawa, Ikuro Kitano, Masaaki Uematsu
AIM: The treatment strategy for hemodialysis (HD) patients with critical limb ischemia (CLI) has been clinically debatable. Here we compared clinical outcomes after bypass surgery (BSX) and after endovascular therapy (EVT) using propensity score matching. METHODS: A retrospective multicenter database of 246 (68 BSX and 178 EVT) consecutive HD patients with CLI (79% with tissue loss) who underwent infrainguinal revascularization from 2007 to 2009 was used to compare clinical outcomes, including overall survival (OS), major amputation (MA), major adverse limb event (MALE: repeat EVT, surgical reconstruction, or MA), and MALE-free survival after BSX vs...
October 13, 2016: Journal of Atherosclerosis and Thrombosis
Ryo Naito, Katsumi Miyauchi, Hiroyuki Daida
Statin treatment to reduce low-density lipoprotein cholesterol (LDL-C) is associated with the prevention of cardiovascular events in Western patients. Similar results have been reported in studies conducted in Japan. However, the dose of statins and the degree of LDL-C reduction achieved with statins are different between Asian and Western patients. In addition, there are limited data regarding racial differences in response to statins. In this review, racial differences between Asians and Westerners in response to statins are described...
October 12, 2016: Journal of Atherosclerosis and Thrombosis
Koichi Kaikita
No abstract text is available yet for this article.
October 12, 2016: Journal of Atherosclerosis and Thrombosis
Tamio Teramoto
No abstract text is available yet for this article.
October 12, 2016: Journal of Atherosclerosis and Thrombosis
Naohisa Tomosugi, Shoko Yamamoto, Masayoshi Takeuchi, Hideto Yonekura, Yasuhito Ishigaki, Noriaki Numata, Shogo Katsuda, Yasuo Sakai
AIM: Collagen tripeptide (CTP) is a functional food with a high content of Gly-X-Y tripeptides derived from collagen. The objective of this study was to evaluate the effect of CTP administration on the development of atherosclerosis in healthy individuals. METHODS: The present study was conducted in the form of an open-label, single-dose trial for 6 months. All subjects ingested CTP twice daily: at breakfast and supper (total intake per day: 16 g). The effect of CTP on atherosclerosis was verified by measuring several indices, including serum lipid levels, toxic advanced glycation end-products (TAGE), and the cardio-ankle vascular index (CAVI), at baseline and 6 months...
October 6, 2016: Journal of Atherosclerosis and Thrombosis
Miki Kikui, Yoshihiro Kokubo, Takahiro Ono, Momoyo Kida, Takayuki Kosaka, Masaaki Yamamoto, Makoto Watanabe, Yoshinobu Maeda, Yoshihiro Miyamoto
AIM: A positive association between metabolic syndrome (MetS) and periodontal status has recently been noted. However, no study has evaluated the relationship by sex and in a general urban population using the uniform definition proposed in the 2009 Joint Interim Statement. The aim of this study was to clarify the relationship between MetS and periodontal status using the uniform definition in a general urban Japanese population. METHODS: A total of 1,856 Japanese men and women (mean age: 66...
October 6, 2016: Journal of Atherosclerosis and Thrombosis
Shinsuke Mori, Keisuke Hirano, Yoshiaki Ito, Masahiro Yamawaki, Motoharu Araki, Norihiro Kobayashi, Hideyuki Takimura, Yasunari Sakamoto, Masakazu Tsutsumi, Takuro Takama, Yohsuke Honda, Takahiro Tokuda, Kenji Makino, Shigemitsu Shirai
AIM: To investigate the relationship between intravascular ultrasound (IVUS) findings and restenosis after stent implantation for long occlusive femoropopliteal (FP) lesions using the intraluminal approach. METHODS: This was a single-center retrospective study of 45 patients (49 lesions) with de novo long occlusive FP lesions treated with bare metal stents implanted using the intraluminal approach under IVUS guidance from April 2007 to December 2014. All patients were followed up at least 12 months...
October 1, 2016: Journal of Atherosclerosis and Thrombosis
Chizuko Maruyama, Rena Nakano, Mitsuha Shima, Asumi Mae, Yuri Shijo, Eri Nakamura, Yuuna Okabe, Sunmi Park, Noriko Kameyama, Satomi Hirai, Mamoru Nakanishi, Kagehiro Uchida, Hiroshi Nishiyama
AIM: We conducted a pilot study to clarify the effects of the Japan Diet nutritional education program on metabolic risk factors for atherosclerotic cardiovascular disease in middle-aged men who were brought up in the westernized dietary environment of modern Japan. METHODS: Thirty-three men, 30-49 years of age, attended a nutrition education class to learn food items and recommended volumes comprising the Japan Diet (more fish, soybeans and soy products, vegetables, seaweed, mushrooms and unrefined cereals, and less animal fat, meat and poultry with fat, sweets, desserts and snacks, and alcoholic drinks), and were encouraged to consume the Japan Diet for 6 weeks...
September 21, 2016: Journal of Atherosclerosis and Thrombosis
Miyuki Hori, Akihiko Kitamura, Masahiko Kiyama, Hironori Imano, Kazumasa Yamagishi, Renzhe Cui, Mitsumasa Umesawa, Isao Muraki, Takeo Okada, Tomoko Sankai, Tetsuya Ohira, Isao Saito, Takeshi Tanigawa, Hiroyasu Iso
AIM: Data for long-term trends in blood pressures, body mass index (BMI), and their relations are needed to set future intervention priorities for prevention of cardiovascular disease. The objective of this study was to investigate these trends revealed by repeated cross-sectional surveys conducted from 1963 to 2013 in a Japanese community. METHODS: Men and women aged 40-79 years who participated in annual cardiovascular checkups were enrolled, and the number of participants ranged between 1,776 and 2,366 with consistently high participation rates for both sexes aged 60-69 years...
September 21, 2016: Journal of Atherosclerosis and Thrombosis
Jin-Tao Wu, De-Yong Long, Shan-Ling Wang
No abstract text is available yet for this article.
September 15, 2016: Journal of Atherosclerosis and Thrombosis
Hsu-Lung Jen, Wei-Hsian Yin, Jaw-Wen Chen, Shing-Jong Lin
AIM: Previous studies demonstrated that endothelin-1 (ET-1) can significantly increase the cell size and stimulate adiponectin expression in cultured human cardiomyocytes (HCM). The aim of the present study was to investigate the effects of fenofibrate, a peroxisome proliferator-activated receptor-α (PPARα) activator, on cell hypertrophy and adiponectin expression in vitro and in a rat model of daunorubicin-induced cardiomyopathy. METHODS: The cultured human cardiomyocytes (HCM) were stimulated with or without ET-1...
September 15, 2016: Journal of Atherosclerosis and Thrombosis
Mami Iida
No abstract text is available yet for this article.
September 14, 2016: Journal of Atherosclerosis and Thrombosis
Yujiro Okute, Tetsuo Shoji, Tomoshige Hayashi, Yukinobu Kuwamura, Mika Sonoda, Katsuhito Mori, Atsushi Shioi, Yoshihiro Tsujimoto, Tsutomu Tabata, Masanori Emoto, Masaaki Inaba
AIM: The cardiothoracic ratio (CTR) on a chest X-ray is an indicator of cardiac enlargement, although its predictive power for cardiovascular disease (CVD) events in chronic kidney disease is unknown. We examined it in a cohort of hemodialysis patients, as compared with an N-terminal fragment of probrain natriuretic peptide (NT-proBNP). METHOD: This was an observational study with cross-sectional and longitudinal analyses including 517 maintenance hemodialysis patients and 122 healthy control subjects...
September 13, 2016: Journal of Atherosclerosis and Thrombosis
Jing Dong, Ying-Zhi Liang, Jie Zhang, Li-Juan Wu, Shuo Wang, Qi Hua, Yu-Xiang Yan
AIM: To explore the relationship between lipometabolism-related microRNAs (miRNAs) in peripheral blood mononuclear cells (PBMCs) and the presence of coronary artery disease (CAD). METHODS: In the present study, 161 stable CAD patients and 149 health controls were enrolled. The expression levels of seven miRNAs (miR-21, miR-24, miR-29a, miR-33a, miR-34a, miR-103a, and miR-122) in PBMCs were qualified by quantitative real-time polymerase chain reaction (qRT-PCR). The miRNA markers that showed significant difference between the two groups were used for further analysis...
September 13, 2016: Journal of Atherosclerosis and Thrombosis
Shigeatsu Hashimoto, Masato Nagai, Shingo Fukuma, Tetsuya Ohira, Mitsuaki Hosoya, Seiji Yasumura, Hiroaki Satoh, Hitoshi Suzuki, Akira Sakai, Akira Ohtsuru, Yukihiko Kawasaki, Atsushi Takahashi, Kotaro Ozasa, Gen Kobashi, Kenji Kamiya, Shunichi Yamashita, Shun-Ichi Fukuhara, Hitoshi Ohto, Masafumi Abe
AIM: After the Great East Japan Earthquake, over 160,000 residents near the Fukushima Daiichi Nuclear Power Plant were forced to evacuate due to a nuclear accident. Health problems in these evacuees have since become major issues. We examined the association between evacuation and incidence of metabolic syndrome (METS) among residents in Fukushima. METHODS: We conducted a cohort study among residents aged 40-74 years without METS at the time of the disaster in Fukushima...
September 13, 2016: Journal of Atherosclerosis and Thrombosis
Daisuke Sanoyama, Mototsugu Nagao, Akira Asai, Yuko Nakamura, Kazumi Sato, Yasushi Nakajima, Shinichi Oikawa, Hitoshi Sugihara
AIM: The clinical significance of energy expenditure (EE) in the treatment of type 2 diabetes has not been fully elucidated. Here we analyzed the relationships between EE and clinical measurements in patients with type 2 diabetes receiving diet therapy. METHODS: A total of 100 patients (34 women and 66 men) with type 2 diabetes admitted to our hospital for glycemic control were enrolled. The participants received an energy-restricted diet during their hospitalization (median, 15 days)...
September 7, 2016: Journal of Atherosclerosis and Thrombosis
Manuel Martínez-Sellés, Luis Alberto Escobar Robledo, Adrian Baranchuk
No abstract text is available yet for this article.
September 6, 2016: Journal of Atherosclerosis and Thrombosis
Ta-Chen Su, Juey-Jen Hwang, Kuo-Chin Huang, Fu-Tien Chiang, Kuo-Liong Chien, Kuo-Yang Wang, Min-Ji Charng, Wei-Chuan Tsai, Lian-Yu Lin, Runar Vige, José Emilio Ruiz Olivar, Chuen-Den Tseng
AIM: Information regarding the effects of omega-3 fatty acid on hypertriglyceridemic patients in Chinese is still limited. This study aimed to investigate the efficacy and safety of Omacor(®), a prescription ethyl-ester omega-3 fatty acid for the treatment of hypertriglyceridemia, administered at doses of 2 g/day and 4 g/day to Taiwanese hypertriglyceridemic patients. METHODS: A multicenter, randomized, double-blind, placebo-controlled, parallel study in adults with hypertriglyceridemia was conducted...
September 6, 2016: Journal of Atherosclerosis and Thrombosis
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