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Journal of Atherosclerosis and Thrombosis

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https://www.readbyqxmd.com/read/27904029/coronary-artery-calcium-and-carotid-artery-intima-media-thickness-and-plaque-clinical-use-in-need-of-clarification
#1
Maryam Zaid, Akira Fujiyoshi, Aya Kadota, Robert D Abbott, Katsuyuki Miura
Atherosclerosis begins in early life and has a long latent period prior to onset of clinical disease. Measures of subclinical atherosclerosis, therefore, may have important implications for research and clinical practice of atherosclerotic cardiovascular disease (ASCVD). In this review, we focus on coronary artery calcium (CAC) and carotid artery intima-media thickness (cIMT) and plaque as many population-based studies have investigated these measures due to their non-invasive features and ease of administration...
December 1, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27904028/prognostic-value-of-eosinophil-to-leukocyte-ratio-in-patients-with-st-elevation-myocardial-infarction-undergoing-primary-percutaneous-coronary-intervention
#2
Takao Konishi, Naohiro Funayama, Tadashi Yamamoto, Toru Morita, Daisuke Hotta, Hiroshi Nishihara, Shinya Tanaka
AIM: Leukocyte profile has been related to clinical outcome in patients with ST-segment elevation (STE) myocardial infarction (MI). However, whether eosinophil to leukocyte ratio (ELR) predicts clinical outcome in patients who have undergone primary percutaneous coronary intervention (PCI) remains unclear. Therefore, we examined the prognostic value of ELR in this patient population. METHODS: We retrospectively analyzed the data of 331 consecutive patients who underwent primary PCI for STEMI between January 2009 and March 2015...
December 1, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27904027/retinal-vascular-changes-and-prospective-risk-of-disabling-dementia-the-circulatory-risk-in-communities-study-circs
#3
Hiroshige Jinnouchi, Akihiko Kitamura, Kazumasa Yamagishi, Masahiko Kiyama, Hironori Imano, Takeo Okada, Renzhe Cui, Mitsumasa Umesawa, Isao Muraki, Mina Hayama-Terada, Ryo Kawasaki, Tomoko Sankai, Tetsuya Ohira, Hiroyasu Iso
AIM: To investigate the association of retinal vascular changes with a risk of dementia in longitudinal population-based study. METHODS: We performed a nested case-control study of 3,718 persons, aged 40-89 years, enrolled between 1983 and 2004. Retinal vascular changes were observed in 351 cases with disabling dementia (average period before the onset, 11.2 years) and in 702 controls matched for sex, age, and baseline year. Incidence of disabling dementia was defined as individuals who received cares for disabilities including dementia-related symptoms and/or behavioral disturbance...
December 1, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27904026/inverse-relationship-between-sleep-duration-and-cardio-ankle-vascular-index-in-children
#4
Noriteru Morita, Isao Kambayashi, Tomoyasu Okuda, Shiro Oda, Shingo Takada, Toshihiro Nakajima, Noriyuki Shide, Hisashi Shinkaiya, Koichi Okita
AIM: Poor sleep has been shown to be associated with the development of cardiovascular risk factors, such as obesity, in both adults and children. This study aimed to investigate the relationship between sleep duration and arterial stiffness indices in Japanese children and early adolescents. METHODS: The data on 102 students (56 males, 46 females; mean age, 11.9±1.8 years) were analyzed. As non-invasive arterial stiffness parameters, the cardio-ankle vascular index (CAVI) and heart-ankle pulse wave velocity (haPWV) were evaluated...
December 1, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27904017/what-does-intravascular-ultrasound-illustrate
#5
Osamu Iida, Mitsuyoshi Takahara
No abstract text is available yet for this article.
November 29, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27890885/medication-adherence-improvement-by-using-administration-timing-simplification-protocol-atsp-in-cardiovascular-disease-patients
#6
Sun Hoi Jung, Ok Sang Lee, Hyang Sook Kim, Chan Soon Park, Hyun Jung Lee, Kyeng Hee Kwon, Hae Young Lee
AIMS: In chronic diseases, keeping adherence to medication is very difficult. The objective of this study was to evaluate the impact of administration timing simplification protocol (ATSP) on medication adherence and clinical parameters of cardiovascular diseases. METHODS: 210 out-patients with cardiovascular disease, who were taking two or more pills of any type of medication per day for more than one year, were enrolled and randomized. The intervention group followed the simplified administration schedule of ATSP with two main strategies: 1) moving medication from "pc" (30 minute after meal) to "stat...
November 25, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27874838/associations-of-cardiovascular-risk-factors-with-carotid-intima-media-thickness-in-middle-age-adults-and-elders
#7
Tzu-Wei Wu, Chung-Lieh Hung, Chun-Chieh Liu, Yih-Jer Wu, Li-Yu Wang, Hung-I Yeh
AIMS: Elevated carotid intima-media thickness (cIMT) is a preclinical phenotype of atherosclerotic diseases. There are significant sex differences in the morbidities of cardiovascular diseases and their major determinants, and we explored the sex-specific effects of cardiovascular factors on cIMT by a community-based study. METHODS: We measured the cIMT and cardiovascular profiles of 1579 residents aged 40-74 years in northern Taiwan. Multivariate regression analyses were used to assess the effects and contributions of these factors on cIMT...
November 18, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27840387/serum-non-high-density-lipoprotein-cholesterol-and-risk-of-cardiovascular-disease-in-community-dwellers-with-chronic-kidney-disease-the-hisayama-study
#8
Tomoko Usui, Masaharu Nagata, Jun Hata, Naoko Mukai, Yoichiro Hirakawa, Daigo Yoshida, Hiro Kishimoto, Takanari Kitazono, Yutaka Kiyohara, Toshiharu Ninomiya
AIM: It is not clear whether elevated serum non-high-density lipoprotein cholesterol (non-HDL-C) levels are a risk factor for cardiovascular disease (CVD) in subjects with chronic kidney disease (CKD) in the general population. METHODS: A total of 2,630 community-dwelling Japanese subjects (1,107 men and 1,523 women) without history of CVD and aged ≥40 years were prospectively followed up for an average of 19 years, and the association between serum non-HDL-C levels and the incidence of type-specific CVD was estimated using a Cox proportional hazards model...
November 12, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27840386/association-of-the-lox-1-rs1050283-polymorphism-with-risk-for-atherosclerotic-cerebral-infarction-and-its-effect-on-slox-1-and-lox-1-expression-in-a-chinese-population
#9
Xin Guo, Yuanyuan Xiang, Heng Yang, Lijin Yu, Xiangdong Peng, Ren Guo
AIMS: The interaction between lectin-like oxidized low density lipoprotein (LDL) receptor-1 (LOX-1) and oxidized LDL (ox-LDL) has been viewed as an important pathogenic factor for cardiovascular diseases. This study aimed to explore the association of a functional polymorphism rs1050283 in the 3'-untranslated region of the LOX-1 gene with atherosclerotic cerebral infarction (ACI) susceptibility, and we also investigated the effects of the rs1050283 polymorphism on LOX-1 expression and serum levels of sLOX-1 in patients with ACI...
November 12, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27840385/calcium-overload-accelerates-phosphate-induced-vascular-calcification-via-pit-1-but-not-the-calcium-sensing-receptor
#10
Asuka Masumoto, Tomohiro Sonou, Masaki Ohya, Mitsuru Yashiro, Yuri Nakashima, Kouji Okuda, Yuko Iwashita, Toru Mima, Shigeo Negi, Takashi Shigematsu
AIM: Vascular calcification (VC) is a risk factor of cardiovascular and all-cause mortality in patients with chronic kidney disease (CKD). CKD-mineral and bone metabolism disorder is an important problem in patients with renal failure. Abnormal levels of serum phosphate and calcium affect CKD-mineral and bone metabolism disorder and contribute to bone disease, VC, and cardiovascular disease. Hypercalcemia is a contributing factor in progression of VC in patients with CKD. However, the mechanisms of how calcium promotes intracellular calcification are still unclear...
November 11, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27840384/association-of-subjective-and-objective-sleep-duration-as-well-as-sleep-quality-with-non-invasive-markers-of-sub-clinical-cardiovascular-disease-cvd-a-systematic-review
#11
Muhammad Aziz, Shozab S Ali, Sankalp Das, Adnan Younus, Rehan Malik, Muhammad A Latif, Choudhry Humayun, Dixitha Anugula, Ghulam Abbas, Joseph Salami, Javier Valero Elizondo, Emir Veledar, Khurram Nasir
AIM: Abnormal daily sleep duration and quality have been linked to hypertension, diabetes, stroke, and overall cardiovascular disease (CVD) morbidity& mortality. However, the relationship between daily sleep duration and quality with subclinical measures of CVD remain less well studied. This systematic review evaluated how daily sleep duration and quality affect burden of subclinical CVD in subjects free of symptomatic CVD. METHODS: Literature search was done via MEDLINE, EMBASE, Web of Science until June 2016 and 32 studies met the inclusion criteria...
November 11, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27829582/postprandial-hyperlipidemia-and-remnant-lipoproteins
#12
Daisaku Masuda, Shizuya Yamashita
Fasting hypertriglyceridemia is positively associated with the morbidity of coronary heart disease (CHD), and postprandial (non-fasting) hypertriglyceridemia is also correlated with the risk status for CHD, which is related to the increase in chylomicron (CM) remnant lipoproteins produced from the intestine. CM remnant particles, as well as oxidized low density lipoprotein (LDL) or very low density lipoprotein (VLDL) remnants, are highly atherogenic and act by enhancing systemic inflammation, platelet activation, coagulation, thrombus formation, and macrophage foam cell formation...
November 8, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27829581/enhanced-intestinal-absorption-of-cholesterol-along-with-increased-chylomicron-remnants-for-de-novo-progression-of-coronary-stenosis
#13
Daisaku Masuda, Shizuya Yamashita
No abstract text is available yet for this article.
November 8, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27803490/impact-of-homocysteine-level-on-long-term-cardiovascular-outcomes-in-patients-after-coronary-artery-stenting
#14
Jih-Kai Yeh, Chun-Chi Chen, Ming-Jer Hsieh, Ming-Lung Tsai, Chia-Hung Yang, Dong-Yi Chen, Shang-Hung Chang, Chao-Yung Wang, Cheng-Hung Lee, I-Chang Hsieh
AIM: The prognostic value of homocysteine (HCY) in patients with coronary artery diseases (CAD) is still controversial. The objective of this study was to investigate whether elevated HCY level at admission predict long-term outcomes in patients after percutaneous coronary interventions (PCI) with coronary artery stenting. METHODS: From the institutional registry of Cardiovascular Atherosclerosis and Percutaneous TrAnsluminal INterventions (CAPTAIN), we enrolled a total of 1,307 patients with documented CAD undergone PCI with bare metal stents from July 2003 to December 2014...
November 1, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27784850/risk-factor-of-cardiovascular-disease-among-older-individuals
#15
Hiroshi Yatsuya, Masaaki Matsunaga, Yuanying Li, Atsuhiko Ota
No abstract text is available yet for this article.
October 26, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27784849/hyperuricemia-as-a-predictive-marker-for-progression-of-nephrosclerosis-clinical-assessment-of-prognostic-factors-in-biopsy-proven-arterial-arteriolar-nephrosclerosis
#16
Kumiko Momoki, Hiroshi Kataoka, Takahito Moriyama, Toshio Mochizuki, Kosaku Nitta
AIM: The influence of serum urate on kidney disease is attracting attention, but the effects of uric acid (UA) on nephrosclerosis have not been elucidated. METHODS: We reviewed data from 45 patients diagnosed with arterial/arteriolar nephrosclerosis. The renal outcomes of the arterial/arteriolar nephrosclerosis patients were assessed by performing logistic and Cox regression analyses. A Kaplan-Meier analysis was used to evaluate the impact of hyperuricemia (HU) on kidney survival...
October 26, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27784848/is-high-serum-ldl-hdl-cholesterol-ratio-an-emerging-risk-factor-for-sudden-cardiac-death-findings-from-the-kihd-study
#17
Setor K Kunutsor, Francesco Zaccardi, Jouni Karppi, Sudhir Kurl, Jari A Laukkanen
AIM: Low-density lipoprotein cholesterol (LDL-c) and high-density lipoprotein cholesterol (HDL-c), which are components of total cholesterol, have each been suggested to be linked to the risk of sudden cardiac death (SCD). However, the relationship between LDL-c/HDL-c ratio and the risk of SCD has not been previously investigated. We aimed to assess the associations of LDL-c, HDL-c, and the ratio of LDL-c/HDL-c with the risk of SCD. METHODS: Serum lipoprotein concentrations were assessed at baseline in the Finnish Kuopio Ischemic Heart Disease prospective cohort study of 2,616 men aged 42-61 years at recruitment...
October 26, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27773886/cdkn2b-methylation-and-aortic-arch-calcification-in-patients-with-ischemic-stroke
#18
Shuyu Zhou, Biyang Cai, Zhizhong Zhang, Yumeng Zhang, Li Wang, Keting Liu, Hao Zhang, Lingli Sun, Huan Cai, Guangming Lu, Xinfeng Liu, Gelin Xu
AIM: CDKN2A/2B near chromosome 9p21 has been proposed as a potential genetic etiology for both atherosclerosis and arterial calcification. DNA methylation, which can change the expression of CDKN2A/2B, may be an underlying mechanism for this association. This study aimed to evaluate whether CDKN2A/2B methylation is related to aortic arch calcification (AAC) in patients with ischemic stroke. METHODS: DNA methylation levels of CDKN2A/2B was measured using venous blood samples in 322 patients with ischemic stroke...
October 21, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27760913/is-the-effect-of-omega-3-polyunsaturated-fatty-acids-dependent-on-life-style-severity-of-disease-and-use-of-concomitant-medications
#19
Ichiro Tatsuno
No abstract text is available yet for this article.
October 18, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27733732/predictive-value-of-aortic-valve-calcification-for-periprocedural-myocardial-injury-in-patients-undergoing-percutaneous-coronary-intervention
#20
Yohei Shibata, Hideki Ishii, Susumu Suzuki, Akihito Tanaka, Yosuke Tatami, Shingo Harata, Tomoyuki Ota, Yusaku Shimbo, Yohei Takayama, Ayako Kunimura, Kenshi Hirayama, Kazuhiro Harada, Naohiro Osugi, Toyoaki Murohara
AIMS: Previous studies have shown that aortic valve calcification (AVC) was associated with cardiovascular events and mortality. On the other hand, periprocedural myocardial injury (PMI) in percutaneous coronary intervention (PCI) is a well-known predictor of subsequent mortality and poor clinical outcomes. The purpose of the study was to assess the hypothesis that the presence of AVC could predict PMI in PCI. METHODS: This study included 370 patients treated with PCI for stable angina pectoris...
October 13, 2016: Journal of Atherosclerosis and Thrombosis
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