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Breast Journal

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https://www.readbyqxmd.com/read/30240110/can-invasive-breast-carcinoma-with-close-or-positive-margins-be-managed-without-a-new-surgery
#1
Jose Luis Guinot, Maria Isabel Tortajada, Miguel Angel Santos, Araceli Moreno, Jesús Fernández, Marina Peña, Francisco Gozalbo, Laura Oliver, Cristina Bosó, Paula Santamaría, Julia Giménez, Leoncio Arribas
We present the long-term outcome (FU 127 months) of a prospective study with 248 breast cancer patients with close or positive surgical margin, treated with 50 Gy whole breast irradiation plus high-dose-rate boost, 3 × 4.4 Gy. Actuarial breast failure at 10/15 years was 6.5%/11.6%; with positive margin (120) 6.8%/14.8%, with margin ≤2 mm (76) 9.8%/9.8%, with margin >2 mm <5 mm (52) 2%/2%. In 90 patients aged ≤50 was 11.9%/17.8%, between 51 and 70, 3.8%/8.2%, >70, 0%. Fibrosis appeared in 26...
September 21, 2018: Breast Journal
https://www.readbyqxmd.com/read/30240101/risk-factors-for-breast-cancer-mortality-evidence-from-brazil
#2
Francisco Winter Dos Santos Figueiredo, Jean Henri Maselli Schoueri, Tábata Cristina do Carmo Almeida, Luis Eduardo Werneck de Carvalho, Fernando Adami
No abstract text is available yet for this article.
September 21, 2018: Breast Journal
https://www.readbyqxmd.com/read/30240099/recurrent-solitary-fibrous-tumor-of-the-breast-magnetic-resonance-imaging-and-pathologic-findings
#3
Bit Na Park, Ok Hee Woo, Chungyeul Kim, Kyu Ran Cho, Bo Kyoung Seo
No abstract text is available yet for this article.
September 21, 2018: Breast Journal
https://www.readbyqxmd.com/read/30240094/impact-of-insurance-coverage-and-socioeconomic-factors-on-screening-mammography-patients-selection-of-digital-breast-tomosynthesis-versus-full-field-digital-mammography
#4
Eniola Falomo, Kelly Myers, Kent F Reichel, Kathryn A Carson, Lisa Mullen, Philip Di Carlo, Susan Harvey
No abstract text is available yet for this article.
September 21, 2018: Breast Journal
https://www.readbyqxmd.com/read/30240080/robotic-nipple-sparing-mastectomy-the-first-experience-from-indian-subcontinent
#5
Suhas Kodasoge Rajappa, Rajeev Kumar, Shubha Garg, Dharma Ram
No abstract text is available yet for this article.
September 21, 2018: Breast Journal
https://www.readbyqxmd.com/read/30240079/a-clinicopathologic-study-of-invasive-apocrine-carcinoma-of-the-breast-a-single-center-experience
#6
Denira Imamovic, Nurija Bilalovic, Faruk Skenderi, Vanesa Beslagic, Timur Ceric, Berisa Hasanbegovic, Semir Beslija, Semir Vranic
No abstract text is available yet for this article.
September 21, 2018: Breast Journal
https://www.readbyqxmd.com/read/30240069/a-rare-case-of-pleomorphic-adenoma-of-the-breast-ultrasonography-and-pathology-findings
#7
Aydan Arslan, Nilgün Güldoğan, Nilgün Kapucuoğlu, Gul Esen, Halil Kara, Cihan Uras
No abstract text is available yet for this article.
September 21, 2018: Breast Journal
https://www.readbyqxmd.com/read/30240068/paraneoplastic-neurologic-syndrome-as-a-presentation-of-underlying-breast-malignancy
#8
Benjamin Laguna, Jessica H Hayward, Amie Y Lee, Bonnie N Joe, Kimberly M Ray
While breast cancer most commonly presents as a screen-detected mammographic finding or a breast symptom, in very rare instances it may first present as a paraneoplastic neurologic syndrome (PNS; Surg Case Rep, 2015;1:59; Ann Neurol 2004;56:715). Fewer than 1% of breast cancer patients have PNS, and an even smaller percentage initially present with neurologic symptoms (J Neurol Neurosurg Psychiatry, 2004;75:ii43). We report a case series of three patients who presented with neurological disorders suspicious for PNS, and were subsequently found to have underlying breast cancer...
September 21, 2018: Breast Journal
https://www.readbyqxmd.com/read/30240064/breast-mri-findings-of-fibroadenoma-with-hemorrhagic-infarction
#9
Shuichi Fukui, Ken Yamaguchi, Takahiko Nakazono, Ryoko Egashira, Jun Nakamura, Masanori Masuda, Hiroyuki Irie
No abstract text is available yet for this article.
September 21, 2018: Breast Journal
https://www.readbyqxmd.com/read/30240061/the-wiser-oncoplastic-reduction-mammaplasty-an-approach-to-challenging-medial-defects
#10
Xiao Zhu, Francesco M Egro, Carolyn De La Cruz
Medial defects created by breast-conservation surgery pose a significant challenge to oncoplastic reduction mammaplasty, especially with superficial tumors that necessitate resection of overlying skin. These tumors lie outside of the standard breast reduction excision pattern, and require modifications to the routine Wise approach. We present one modification - the "Wiser" oncoplastic reduction mammaplasty technique - that utilizes spared tissue along the lower pole, and a medial dermoglandular pedicle to address both skin and parenchymal defects created by the tumor resection...
September 21, 2018: Breast Journal
https://www.readbyqxmd.com/read/30230142/partial-breast-irradiation-for-ductal-carcinoma-in-situ-the-goldilocks-principle
#11
Icro Meattini, Philip Poortmans, Lorenzo Livi, Orit Kaidar Person, Stefania Pallotta, Carlotta Becherini, Livia Marrazzo
No abstract text is available yet for this article.
September 19, 2018: Breast Journal
https://www.readbyqxmd.com/read/30230131/malignant-peripheral-nerve-sheath-tumor-of-the-breast-in-a-patient-with-neurofibromatosis-1
#12
Sarah E Bonnet, Justine K Kang-Chapman, Kaila A Buckley, Xiaoyan Cui, Valerie P Grignol, Jeffrey R Hawley
No abstract text is available yet for this article.
September 19, 2018: Breast Journal
https://www.readbyqxmd.com/read/30230127/the-use-of-chromophore-gel-assisted-blue-light-phototherapy-lumiheal-for-the-treatment-of-surgical-site-infections-in-breast-surgery
#13
Tommaso Fogacci, Federico Cattin, Gloria Semprini, Gianluca Frisoni, Luca Fabiocchi, Domenico Samorani
No abstract text is available yet for this article.
September 19, 2018: Breast Journal
https://www.readbyqxmd.com/read/30230119/direct-to-implant-breast-reconstruction-higher-complication-rate-vs-cosmetic-benefits
#14
Daphne Gschwantler-Kaulich, Carmen Leser, Mohamed Salama, Christian Fridolin Singer
BACKGROUND: Since skin- and nipple-sparing mastectomies (SSM/NSM) are now considered oncologically safe options, the number of immediate implant-based breast reconstructions (IBBR) has increased. We present our experience with different techniques of immediate and delayed IBBR over a period of 5 years. METHODS: A single center, retrospective, cohort study was performed from January 2008 to January 2013. Complications, reconstructive failure, contralateral adjustment, cosmetic outcome, patient's quality of life, and the thickness of the overlying tissue were compared between different techniques of immediate and delayed IBBR...
September 19, 2018: Breast Journal
https://www.readbyqxmd.com/read/30230117/breast-cancer-histopathology-is-predictive-of-low-risk-oncotype-dx-recurrence-score
#15
Parker C Wilson, Anees B Chagpar, Ali F Cicek, Veerle Bossuyt, Natalia Buza, Sarah Mougalian, Brigid K Killelea, Natalie Patel, Malini Harigopal
BACKGROUND: Oncotype Dx is a genetic test that has been incorporated into the 2017 AJCC breast cancer staging system for ER positive, HER2-negative, lymph node-negative patients to predict the risk of recurrence. Recent data suggest that immunohistochemistry (ER, PR, HER2, and Ki-67) and histologic subtype may identify patients that will not benefit from Oncotype Dx testing. METHODS: A total of 371 patients underwent Oncotype Dx testing at our institution from 2012 to 2016...
September 19, 2018: Breast Journal
https://www.readbyqxmd.com/read/30230113/comparison-of-magee-and-oncotype-dx-recurrence-scores-in-estrogen-receptor-positive-breast-cancers
#16
Ann E Walts, James M Mirocha, Shikha Bose
Data from pathology reports of estrogen receptor positive (ER+) breast cancers with Ki67 < 14% (luminal-A; n = 128) and Ki67 ≥ 14% (luminal-B; n = 100) were entered into the automatic recurrence score (RS) calculator accessible at the University of Pittsburgh Department of Pathology website. Using RS obtained with Magee equations #1 and #3, an average modified Magee recurrence score (AMM RS) was calculated for each tumor. The AMM RS and the Oncotype DX RS (Onco RS) were compared per tumor and associated with follow-up...
September 19, 2018: Breast Journal
https://www.readbyqxmd.com/read/30230111/pd-l1-expression-and-cd8-positive-t-cells-are-associated-with-favorable-survival-in-her2-positive-invasive-breast-cancer
#17
Yanjun Hou, Hiroaki Nitta, Lai Wei, Peter M Banks, Maryam Lustberg, Robert Wesolowski, Bhuvaneswari Ramaswamy, Anil V Parwani, Zaibo Li
Programmed cell death 1 (PD-1) and its ligand (PD-L1) are key physiologic suppressors of the cytotoxic immune reaction. However, to date, the combination of PD1/PD-L1 expression and tumor-infiltrating lymphocytes (TILs) and antigen-presenting cells has been only minimally reported in breast carcinoma, in particular in relation to HER2-positive cases. The goal of this study was to evaluate both cellular tumoral immune reaction and PD-L1/PD1 distribution in HER2-positive cases, as well as any associations with clinical outcome using conventional chemotherapy combined with HER2 blocking...
September 19, 2018: Breast Journal
https://www.readbyqxmd.com/read/30230095/comparing-breast-biomarker-status-between-routine-immunohistochemistry-and-fish-studies-and-oncotype-dx-testing-a-study-of-610-cases
#18
Cameron Neely, Shuo You, Pia M Mendoza, Ritu Aneja, Aysegul A Sahin, Xiaoxian Li
INTRODUCTION: Oncotype DX (ODX) testing uses reverse transcription polymerase chain reaction (RT-PCR) to predict distant recurrence rate of estrogen receptor positive (ER+)/HER2-negative (HER2-)/lymph node-negative (LN-) breast cancers. ODX also reports the status of breast cancer biomarkers, ER, progesterone receptor (PR), and HER2. This study examined the discrepancy rate of breast cancer biomarker status as reported by ODX vs routinely used immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) methods...
September 19, 2018: Breast Journal
https://www.readbyqxmd.com/read/30216598/nipple-sparing-mastectomy-with-periareolar-incision-and-two-stage-reconstruction-initial-analysis-of-31-cases
#19
Francisco Pimentel Cavalcante, Marcos Venício Alves Lima
Surgical treatment of breast cancer has changed considerably over the past four decades, culminating in the substitution of conservative approaches for Halsted's paradigm from 1894. In parallel, many breast reconstruction techniques have been proposed for patients requiring mastectomy with loss of the nipple-areola complex (NAC). Myocutaneous flaps were once the most common form of reconstruction, but recently the use of implants and nipple-sparing mastectomy (NSM) in one or two stages has gained popularity...
September 14, 2018: Breast Journal
https://www.readbyqxmd.com/read/30216597/a-new-risk-stratification-score-for-the-management-of-ultrasound-detected-b3-breast-lesions
#20
Michela Giuliani, Pierluigi Rinaldi, Rossella Rella, Anna D'Angelo, Giorgio Carlino, Amato Infante, Maurizio Romani, Enida Bufi, Paolo Belli, Riccardo Manfredi
To develop a predictive scoring system for ultrasound-detected B3 lesions at ultrasound-guided core needle biopsy (US-CNB). A total of 2724 consecutive US-CNBs performed in our Institution (January 2011 to December 2014) were retrospectively reviewed. Inclusion criteria were as follows: (a) histopathological examination of the entire lesion or (b) availability of radiologic follow-up (FUP) ≥24 months. Patient- and lesion-related variables-patients' age, lesion consistency, lesion size, vascularization, BI-RADS category, and US-CNB result-were analyzed...
September 14, 2018: Breast Journal
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