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Breast Journal

Giovanni Corso, Brunella Di Nubila, Angelo Ciccia, Elisa De Camilli, Elisa Vicini, Chiara Trentin, Germana Lissidini, Linda Cairns, Paolo Veronesi, Viviana Galimberti
Granular cell tumor is a rare condition that occasionally affects breast parenchyma: approximately, 5%-15% of all granular cell tumors represent 1:1000 of breast tumors. In this study, we reported a consecutive series of 12 patients with primary granular cell tumor of the breast observed at our institute, focusing attention on preoperative management, surgical approach, and long-term follow-up. Eight cases (8/12; 66.78%) presented with left-breast tumors; in the majority of patients (11/12; 91.7%), the lesion was identified in one of the upper quadrants...
June 13, 2018: Breast Journal
Grace Neville, Cathleen O' Neill, Rosemary Murphy, Mark Corrigan, Paul H Redmond, Linda Feeley, Michael W Bennett, Fionnuala O'Connell, Tara Jane Browne
Fibroadenomas (FA) are the most common benign tumor in the female breast. Most are managed conservatively provided there is clinical, radiologic, and pathologic concordance. However, surgical excision is typically recommended for cellular fibroepithelial lesions or those lesions with clinical, radiologic, or pathologic features concerning for phyllodes tumor (PT). Some studies have suggested surgical excision in all FA >30 mm to reduce core needle biopsy (CNB) sampling errors. The aim of our study was to evaluate, in the absence of any other concerning clinicopathologic features, whether surgical excision of FA was warranted based on size criteria alone...
May 25, 2018: Breast Journal
Sergey Melnov, Patricia Murphy, Thomas Foley, Eldar Nadyrov, Vyacheslav Kipen, Boris Leushev, Francesmary Modugno
No abstract text is available yet for this article.
May 21, 2018: Breast Journal
Constance A Roche, Rong Tang, Suzanne B Coopey, Kevin S Hughes
Patients with atypical hyperplasia and lobular carcinoma in situ (LCIS) (atypical breast lesions) are at high risk of developing breast cancer, and chemoprevention has been shown to confer a substantial reduction in that risk. Despite this, the overall rate of chemoprevention utilization in this group is low. This study evaluates the efficacy of a formal individualized education and counseling session on patient acceptance and adherence to chemoprevention. Patients with atypical breast lesions having an individualized education and counseling session in a single surgical oncology practice were prospectively entered into a database from 2001 to 2016, and with IRB approval, their data were analyzed...
May 21, 2018: Breast Journal
Jamie Caughran, Tom M Braun, Tara M Breslin, Daniel R Smith, Jennifer L Kreinbrink, Grace K Parish, Alan T Davis, Teresa A Bacon-Baguley, Samuel M Silver, Norah L Henry
In 2009, the revised United States Preventive Services Task Force (USPSTF) guidelines recommended against routine screening mammography for women age 40-49 years and against teaching self-breast examinations (SBE). The aim of this study was to analyze whether breast cancer method of presentation changed following the 2009 USPSTF screening recommendations in a large Michigan cohort. Data were collected on women with newly diagnosed stage 0-III breast cancer participating in the Michigan Breast Oncology Quality Initiative (MiBOQI) registry at 25 statewide institutions from 2006 to 2015...
May 21, 2018: Breast Journal
Yaser Mansoori, Mohammad Bagher Tabei, Alireza Askari, Pantea Izadi, Abdolreza Daraei, Milad Bastami, Mohammad Mehdi Naghizadeh, Ziba Nariman-Saleh-Fam, Behnam Mansoori, Javad Tavakkoly-Bazzaz
Long noncoding RNAs (lncRNAs) constitute a major class of the human transcriptome which play crucial roles in the key biological processes of both normal and malignant breast cells. Although the aberrant expression of lncRNAs has been well-documented in breast cancer (BC), little is currently known about the association between their expression levels in the breast tissue of healthy women and BC risk factors, especially the reproductive or demographic characteristics that are among the most well-known BC risk modifiers...
May 21, 2018: Breast Journal
Kazuaki Nakashima, Takayoshi Uematsu, Takashi Sugino, Kaoru Takahashi, Seiichirou Nishimura, Yukiko Tadokoro, Tomomi Hayashi
We investigated the radiologic-pathologic correlation of a strong hypointense rim on T2-weighted images (T2-hypo-rim) surrounding breast mass lesions and evaluated its clinical significance. We retrospectively reviewed 3503 consecutive breast magnetic resonance imaging (MRI) examinations. The T2-hypo-rim was defined as a border of strong hypointensity compared with the fat signal on fat-suppressed T2-weighted images. Detected lesions with T2-hypo-rim were classified as a solid or cystic mass with MRI and correlated with histopathologic findings...
May 21, 2018: Breast Journal
Michael Sosin, Aiste Gulla, Lindsay Potdevin, Solange E Cox, Alex J Bartholomew, Sulakshana Seevaratnam, Manisha Sigdel, Troy A Pittman, Shawna C Willey, Eleni A Tousimis
The aim of this study is to assess the complication profile and impact on patient-reported quality of life in those undergoing nipple-sparing mastectomy (NSM) with immediate breast reconstruction and subsequent prosthetic reconstruction in patients with prior breast radiation therapy (pRT) vs those receiving adjuvant post-mastectomy radiation therapy (PMRT). An IRB-approved, retrospective analysis was performed from 2002 to 2014 to identify NSM patients that underwent pRT or PMRT. A 22-item Likert scale questionnaire was administered by a third party to register patient-reported quality of life...
May 20, 2018: Breast Journal
Ehsan H Balagamwala, Bindu V Manyam, Charles Marc Leyrer, Naveen Karthik, Timothy Smile, Rahul D Tendulkar, Sheen Cherian, Diane Radford, Zahraa Al-Hilli, Frank Vicini, Chirag Shah
We evaluated the proportion of patients eligible for alternatives to standard whole breast irradiation (WBI) following breast-conserving surgery using the National Cancer Database (NCDB). Using the 2016 dataset, Stage I-III patients were identified. Eligibility for hypofractionated WBI (HFRT), accelerated partial breast irradiation (APBI) and endocrine therapy (ET-alone) was defined using eligibility from large clinical trials as well as consensus guidelines. For patients with pN0 breast cancer, 20.6% and 37...
May 20, 2018: Breast Journal
Miriam David, Priyanka Handa, Maria Castaldi
We have retrospectively examined a wide range of clinical characteristics, sonographic features, microbiology, and antibiotic regimens in patients with breast abscesses to seek predictive features related to outcome. Because consensus for optimal treatment of breast abscesses has moved toward minimally invasive management using single or repeated needle aspiration (ASP) coupled with adjuvant antibiotics, we assessed whether any factors correlate with the need for repeat procedures by analyzing the number of ASPs and/or surgical incision and drainage (I&D) per abscess...
May 20, 2018: Breast Journal
Yasemin Durum Polat, Füsun Taşkın, Mehmet Burak Çildağ, Ahmet Tanyeri, Aykut Soyder, Filiz Ergin
To investigate the contribution of breast tomosynthesis to intraoperative specimen evaluation in subjects with breast cancer. Approval was obtained from the hospital ethics committee. Specimen mammography, tomosynthesis, and, if available, ultrasonography images were retrospectively assessed for 208 women who had undergone conservative surgery at our hospital between January 2013 and April 2016 after being diagnosed with breast cancer. The success of mammography, tomosynthesis, and ultrasonography in lesion detection and characterization was evaluated...
May 20, 2018: Breast Journal
JoonGoon Kim, MoonHyung You, YeonWoong Kim, DongHoon Shin, JongSoo Choi
No abstract text is available yet for this article.
May 20, 2018: Breast Journal
Salma Moalla, Salma Gharbi, Chaouki Mbarki, Hajer Chennoufi, Saousen Melliti, Sana Mezghani Boussetta
No abstract text is available yet for this article.
May 20, 2018: Breast Journal
Megan Kalambo, Gary J Whitman
No abstract text is available yet for this article.
May 20, 2018: Breast Journal
Sarah P Rooney, Shirley Hoffman, John C Perrin, Kara J Milliron, Alexis V Nees, Julie M Jorns
No abstract text is available yet for this article.
May 20, 2018: Breast Journal
Imtinene Belaid, Leila Ben Fatma, Faten Ezzairi, Makrem Hochlaf, Imene Chabchoub, Olfa Gharbi, Salma Gahbiche, Moncef Mokni, Abdelfattah Zakhama, Mohamed Bibi, Hedi Khairi, Slim Ben Ahmed
No abstract text is available yet for this article.
May 20, 2018: Breast Journal
Mary C White, Ashwini Soman, Clarice R Weinberg, Juan L Rodriguez, Susan A Sabatino, Lucy A Peipins, Lisa DeRoo, Hazel B Nichols, M Elizabeth Hodgson, Dale P Sandler
Although annual breast magnetic resonance imaging (MRI) is recommended for women at high risk for breast cancer as an adjunct to screening mammography, breast MRI use remains low. We examined factors associated with breast MRI use in a cohort of women with a family history of breast cancer but no personal cancer history. Study participants came from the Sister Study cohort, a nationwide, prospective study of women with at least 1 sister who had been diagnosed with breast cancer but who themselves had not ever had breast cancer (n = 17 894)...
May 20, 2018: Breast Journal
Yang Yang, Yingjian He, Zhaoqing Fan, Yiqiang Liu, Tao Ouyang
There is no previous predictive model to assess risk of nonsentinel lymph node metastases (NSLN) in sentinel lymph node (SLN)-positive breast cancer patients after neoadjuvant chemotherapy (NAT). Our goal was to develop a new predictive model for SLN-positive patients after NAT, and validate this new model. A series of 513 patients with metastases in SLN who received NAT were used to evaluate factors affecting NSLN status. Logistic regression analysis was performed to develop a predictive model, which was validated by a subsequent prospective 138 patients...
May 20, 2018: Breast Journal
Angelena Crown, Lauren Scovel, Shanley Deal, Dawna Kramer, Debra Wechter, Janie Grumley
No abstract text is available yet for this article.
May 8, 2018: Breast Journal
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