Francisco Llavero, Lidia B Alejo, Carmen Fiuza-Luces, Alejandro López Soto, Pedro L Valenzuela, Adrián Castillo-García, Javier S Morales, David Fernández, Itziar Pagola Aldazabal, Manuel Ramírez, Alejandro Santos-Lozano, José L Zugaza, Alejandro Lucia
BACKGROUND: Regular exercise, particularly moderate-intensity continuous training (MICT), can improve immune function. Natural killer (NK) cells, a subset of lymphocytes that react to infections, are the most responsive innate immune cells to exercise, but the mechanisms underlying this are poorly understood. A type of exercise training that is gaining popularity in recent years is high-intensity interval training (HIIT), but how it affects NK cells is largely unknown. In fact, intense exercise has been traditionally viewed as a potential stressor to immune homeostasis...
2021: Exercise Immunology Review