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European Journal of Oral Sciences

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https://www.readbyqxmd.com/read/29226456/cigarette-smoke-extract-induces-oral-squamous-cell-carcinoma-cell-invasion-in-a-receptor-for-advanced-glycation-end-products-dependent-manner
#1
Steven Chapman, Madison Mick, Parker Hall, Camilo Mejia, Stephanie Sue, Bihishta Abdul Wase, Margaret A Nguyen, Evan C Whisenant, Shalene H Wilcox, Duane Winden, Paul R Reynolds, Juan A Arroyo
Oral squamous cell carcinoma (OSCC) affects approximately 30,000 people and is associated with tobacco use. Little is known about the mechanistic effects of second-hand smoke in the development of OSSC. The receptor for advanced glycation end-products (RAGE) is a surface receptor that is upregulated by second-hand smoke and inhibited by semi-synthetic glycosaminoglycan ethers (SAGEs). Our objective was to determine the role of RAGE during cigarette smoke extract-induced cellular responses and to use SAGEs as a modulating factor of Ca9-22 OSCC cell invasion...
December 11, 2017: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29197133/perceptions-of-the-dental-profession-a-comparative-analysis-through-scale-development
#2
Burak Buldur, Jason M Armfield
Dentistry is a science-based profession that has a close interaction with people and society. However, despite this close interaction, perceptions of the dental profession by both patients and dental professionals have received little research attention. The purpose of this study was to compare the perceptions of dentists, dental students, and patients toward the dental profession through the development and testing of the Dental Profession Perceptions Scale (DPPS). The DPPS contains a total of 17 items measured on a 5-point Likert response scale...
December 2, 2017: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29171091/internal-fit-of-three-unit-fixed-dental-prostheses-produced-by-computer-aided-design-computer-aided-manufacturing-and-the-lost-wax-metal-casting-technique-assessed-using-the-triple-scan-protocol
#3
Bjørn E Dahl, Jon E Dahl, Hans J Rønold
Suboptimal adaptation of fixed dental prostheses (FDPs) can lead to technical and biological complications. It is unclear if the computer-aided design/computer-aided manufacturing (CAD/CAM) technique improves adaptation of FDPs compared with FDPs made using the lost-wax and metal casting technique. Three-unit FDPs were manufactured by CAD/CAM based on digital impression of a typodont model. The FDPs were made from one of five materials: pre-sintered zirconium dioxide; hot isostatic pressed zirconium dioxide; lithium disilicate glass-ceramic; milled cobalt-chromium; and laser-sintered cobalt-chromium...
November 24, 2017: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29159829/calcium-hydroxide-regulates-transcription-of-the-bone-sialoprotein-gene-via-a-calcium-sensing-receptor-in-osteoblast-like-ros-17-2-8-cells
#4
Shuang Wang, Keisuke Noda, Yuanyuan Yang, Zhengyan Shen, Zhen Chen, Yorimasa Ogata
Bone sialoprotein (BSP) is a glycoprotein associated with mineralized tissues. In this study, we investigated the regulation of Bsp transcription by calcium hydroxide [Ca(OH)2 ] in rat osteosarcoma-derived osteoblast-like ROS 17/2.8 cells and stromal bone marrow cells. Application of Ca(OH)2 (0.4 mM) increased the levels of runt-related transcription factor 2 (Runx2) and BspmRNAs at 3 and 6 h and the level of BSP protein at 12 h. Transient transfection analyses were performed using chimeric constructs encompassing different regions of the rat Bsp gene promoter ligated to a luciferase reporter gene...
November 21, 2017: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29148101/homeobox-protein-msx-1-inhibits-expression-of-bone-morphogenetic-protein-2-bone-morphogenetic-protein-4-and-lymphoid-enhancer-binding-factor-1-via-wnt-%C3%AE-catenin-signaling-to-prevent-differentiation-of-dental-mesenchymal-cells-during-the-late-bell-stage
#5
Xiao-Yu Feng, Xiao-Shan Wu, Jin-Song Wang, Chun-Mei Zhang, Song-Lin Wang
Homeobox protein MSX-1 (hereafter referred to as MSX-1) is essential for early tooth-germ development. Tooth-germ development is arrested at bud stage in Msx1 knockout mice, which prompted us to study the functions of MSX-1 beyond this stage. Here, we investigated the roles of MSX-1 during late bell stage. Mesenchymal cells of the mandibular first molar were isolated from mice at embryonic day (E)17.5 and cultured in vitro. We determined the expression levels of β-catenin, bone morphogenetic protein 2 (Bmp2), Bmp4, and lymphoid enhancer-binding factor 1 (Lef1) after knockdown or overexpression of Msx1...
November 17, 2017: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29131414/oral-health-related-quality-of-life-measured-using-the-five-item-version-of-the-oral-health-impact-profile-in-relation-to-socio-economic-status-a-population-survey-in-sweden
#6
Ulla Wide, Magnus Hakeberg
Oral health-related quality of life (OHRQoL) is an important patient-reported outcome measure in dental research. This study was conducted to analyse the association between OHRQoL, as measured using the five-item version of the Oral Health Impact Profile (OHIP-5), and different socio-economic indices. A national survey of randomly selected adult individuals in Sweden (n = 3,500) was performed using telephone interviews. The questions asked for the purpose of this study were defined by the items of the OHIP-5, just as questions were asked regarding socio-economic variables, including education, income, and economic resources...
November 13, 2017: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29130564/effect-of-non-thermal-atmospheric-plasma-on-the-dentin-surface-topography-and-composition-and-on-the-bond-strength-of-a-universal-adhesive
#7
Ana P Ayres, Jean J Bonvent, Borys Mogilevych, Luis E S Soares, Airton A Martin, Glaucia M Ambrosano, Fábio D Nascimento, Bart Van Meerbeek, Marcelo Giannini
This study investigated the effect of application of non-thermal atmospheric plasma (NTAP) on the topography and composition of the dentin surface, as well as the microtensile bond strength (μTBS) of a universal adhesive to NTAP-treated dentin. Exposed flat dentin surfaces from human third molars were either treated with NTAP for 10 and 30 s or untreated (control). The dentin-surface topography and chemical composition were characterized by atomic force microscopy (n = 3) and Raman confocal spectroscopy (n = 5), respectively...
November 11, 2017: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29114927/genetic-study-of-non-syndromic-tooth-agenesis-through-the-screening-of-paired-box-9-msh-homeobox-1-axin-2-and-wnt-family-member-10a-genes-a-case-series
#8
Marwa Haddaji Mastouri, Peter De Coster, Aicha Zaghabani, Frej Jammali, Nabiha Raouahi, Amina Ben Salem, Ali Saad, Paul Coucke, Dorra H'mida Ben Brahim
Non-syndromic tooth agenesis (NSTA) is the most common developmental anomaly in humans. Several studies have been conducted on dental agenesis and numerous genes have been identified. However, the pathogenic mechanisms responsible for NSTA are not clearly understood. We studied a group of 28 patients with sporadic NSTA and nine patients with a family history of tooth agenesis. We focused on four genes - paired box 9 (PAX9), Wnt family member 10A (WNT10A), msh homeobox 1 (MSX1), and axin 2 (AXIN2) - using direct Sanger sequencing of the exons and intron-exon boundaries...
November 8, 2017: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29110340/effect-of-topical-fluoride-application-on-enamel-after-in-office-bleaching-as-evaluated-using-a-novel-hardness-tester-and-a-transverse-microradiography-method
#9
Mai Fukuyama, Chiharu Kawamoto, Pipop Saikaew, Yasuhiro Matsuda, Ricardo M Carvalho, Denis Selimovic, Hidehiko Sano
This study evaluated the effect of topical fluoride application on enamel hardness after in-office bleaching. Twelve human incisors were cut along the long axis, resulting in 24 halves used in four treatment groups (n = 6 in each group): (i) untreated group (C); (ii) in-office bleaching material (B); (iii) treatment with surface reaction-type prereacted glass-ionomer varnish after in-office bleaching (B+PRG); and (iv) treatment with acidulated phosphate fluoride solution after bleaching (B+F). All specimens were subjected to pH-cycling for 4 wk...
November 7, 2017: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29105170/influence-of-glutamate-evoked-pain-and-sustained-elevated-muscle-activity-on-blood-oxygenation-in-the-human-masseter-muscle
#10
Shunichi Suzuki, Taro Arima, Yoshimasa Kitagawa, Peter Svensson, Eduardo Castrillon
This study aimed to investigate the effect of glutamate-evoked masseter muscle pain on intramuscular oxygenation during rest and sustained elevated muscle activity (SEMA). Seventeen healthy individuals participated in two sessions in which they were injected with glutamate and saline in random order. Each session was divided into three, 10-min periods. During the first (period 1) and the last (period 3) 10-min periods, participants performed five intercalated 1-min bouts of masseter SEMA with 1-min periods of 'rest'...
November 3, 2017: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29083074/oridonin-induces-apoptosis-in-human-oral-cancer-cells-via-phosphorylation-of-histone-h2ax
#11
In-Hyoung Yang, Ji-Ae Shin, Kyung-Eun Lee, Junghyun Kim, Nam-Pyo Cho, Sung-Dae Cho
Oridonin, a natural diterpenoid purified from Rabdosia rubescens, has displayed beneficial biological activities, including anti-proliferation and anti-angiogenesis effects, in various types of cancers. However, the anti-cancer potential of oridonin and its mechanism in oral cancer have never previously been studied. In this study, we assessed the role of oridonin as an inducer of apoptosis in HSC-3 and HSC-4 human oral cancer cells. Our results showed that oridonin reduces the viability of human oral cancer cells and significantly increases the expression of γH2AX, a well-known marker of DNA damage...
October 30, 2017: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29083073/dental-hygienist-attendance-and-its-covariates-in-an-ageing-swedish-cohort
#12
Anne N Åstrøm, Gunnar Ekbäck, Sven Ordell, Stein A Lie, Ferda Gulcan
Delegation of tasks between professional groups is important to make health-care services accessible and effective for ageing people. Focussing on a Swedish 1942 birth cohort and guided by Andersen's Behavioral Model, this study assessed dental hygienist attendance from age 50 to age 70 and identified covariates at the population-averaged and person-specific levels. In 1992, a census of 50-yr-old subjects was invited to participate in a questionnaire survey. Of the 6,346 respondents, 3,585 completed follow-ups in 1997, 2002, 2007, and 2012...
October 30, 2017: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29024129/efficacy-of-vitamins-e-and-c-for-reversing-the-cytotoxic-effects-of-nicotine-and-cotinine
#13
Maryam Torshabi, Zeinab Rezaei Esfahrood, Mahshid Jamshidi, Abbas Mansuri Torshizi, Samira Sotoudeh
Nicotine has adverse cellular and molecular effects on oral mucosa, bone, and teeth. Vitamin E (α-tocopherol) and vitamin C (ascorbic acid) are biological antioxidants with positive effects on wound healing and bone formation. This in vitro study sought to assess the cytotoxic effects of different concentrations of nicotine and cotinine (a metabolite of nicotine) on MG-63 osteoblast-like cells and human gingival fibroblasts (HGFs) in the presence and absence of antioxidant vitamins E and C (separately and combined)...
October 12, 2017: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29024061/in-vitro-studies-of-the-antimicrobial-effect-of-non-thermal-plasma-activated-water-as-a-novel-mouthwash
#14
Yinglong Li, Jie Pan, Guopin Ye, Qian Zhang, Jing Wang, Jue Zhang, Jing Fang
The aim of this study was to evaluate the antimicrobial effects of non-thermal plasma-activated water (PAW) as a novel mouthwash in vitro. Three representative oral pathogens - Streptococcus mutans, Actinomyces viscosus and Porphyromonas gingivalis - were treated with PAW. The inactivation effect was evaluated using the colony-forming unit (CFU) method, and the morphological and structural changes of a cell were observed by scanning electron microscopy and transmission electron microscopy (TEM). The physicochemical properties of PAW were analysed, and its influence on the leakage of intracellular proteins and DNA was evaluated...
October 11, 2017: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29023985/interaction-between-calcitonin-gene-related-peptide-immunoreactive-neurons-and-satellite-cells-via-p2y12-r-in-the-trigeminal-ganglion-is-involved-in-neuropathic-tongue-pain-in-rats
#15
Shiori Sugawara, Shinji Okada, Ayano Katagiri, Hiroto Saito, Tatsuro Suzuki, Hiroki Komiya, Kohei Kanno, Kinuyo Ohara, Toshimitsu Iinuma, Akira Toyofuku, Koichi Iwata
The P2Y12 receptor expressed in satellite cells of the trigeminal ganglion is thought to contribute to neuropathic pain. The functional interaction between neurons and satellite cells via P2Y12 receptors and phosphorylated extracellular signal-regulated kinase 1/2 (pERK1/2) underlying neuropathic pain in the tongue was evaluated in this study. Expression of P2Y12 receptor was enhanced in pERK1/2-immunoreactive cells encircling trigeminal ganglion neurons after lingual nerve crush. The administration to lingual nerve crush rats of a selective P2Y12 receptor antagonist, MRS2395, attenuated tongue hypersensitivity to mechanical and heat stimulation and suppressed the increase in the relative numbers of calcitonin gene-related peptide (CGRP)-immunoreactive neurons and neurons encircled by pERK1/2-immunoreactive cells...
October 11, 2017: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/28921710/non-stick-properties-of-thin-film-coatings-on-dental-restorative-instruments
#16
Jarmo Leppäniemi, Sasha Hoshian, Kimmo Suomalainen, Toni Luoto, Ville Jokinen, Jari Koskinen
The non-stick properties of thin-film coatings on dental-restorative instruments were investigated by static contact-angle measurement using dental filler resin as well as by scanning electron microscopy of the amount of sticking dental restorative material. Furthermore, using a customized dipping measurement set-up, non-stick properties were evaluated by measuring force-by-time when the instrument was pulled out of restorative material. Minor improvements in non-stick properties were obtained with commercial diamond-like carbon and commercial polytetrafluoroethylene-based coatings...
September 18, 2017: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29130547/mir-140-5p-mediated-regulation-of-the-proliferation-and-differentiation-of-human-dental-pulp-stem-cells-occurs-through-the-lipopolysaccharide-toll-like-receptor-4-signaling-pathway
#17
De-Gang Sun, Bing-Chang Xin, Di Wu, Lei Zhou, Hong-Bin Wu, Wen Gong, Jian Lv
Human dental pulp stem cells (DPSCs) are oral mesenchymal stem cells with potential to differentiate into various cell types. Recent studies of DPSCs have focused on microRNAs (miRNAs), a class of small noncoding RNAs that play crucial roles in regulating DPSC phenotypes. In the current study, the expression of miR-140-5p was significantly decreased during lipopolysaccharide (LPS)-mediated differentiation of DPSCs in vitro. Overexpression of miR-140-5p enhanced proliferation of DPSCs and inhibited DPSC differentiation, whereas suppression of miR-140-5p produced the opposite effect...
December 2017: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29130545/author-guidelines
#18
(no author information available yet)
No abstract text is available yet for this article.
December 2017: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/28872190/author-guidelines
#19
(no author information available yet)
No abstract text is available yet for this article.
October 2017: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/28833699/impaired-polymorphonuclear-neutrophils-in-the-oral-cavity-of-edentulous-individuals
#20
Patrick Rijkschroeff, Bruno G Loos, Elena A Nicu
Oral health is characterized by functional oral polymorphonuclear neutrophils (oPMNs). Edentulism might be associated with a loss of oPMNs because these cells enter the oral cavity primarily through the gingival crevices. The main aim of this study was to investigate the numbers of oPMNs in rinse samples obtained from edentulous (n = 21) and dentate (n = 20) subjects. A second study aim was to investigate possible differences between oPMNs and peripheral blood polymorphonuclear neutrophils (cPMNs). Apoptosis/necrosis and cell-activation markers (CD11b, CD63 and CD66b) were analyzed using flow cytometry...
October 2017: European Journal of Oral Sciences
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