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European Journal of Oral Sciences

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https://www.readbyqxmd.com/read/29752756/soluble-urokinase-type-plasminogen-activator-receptor-is-associated-with-signs-of-periodontitis-in-adolescents
#1
Peter D Skottrup, Gunnar Dahlén, Vibeke Baelum, Rodrigo Lopez
Owing to its molecular stability in body fluids, soluble urokinase-type plasminogen activator receptor (suPAR) is used as a biomarker for the level of systemic inflammation. This study compares the suPAR levels in serum with those in the saliva of adolescents and evaluates their association with the periodontal conditions. Adolescents identified as screen positive (n = 87) or screen negative (n = 73) for periodontitis had saliva and serum samples taken, along with subgingival plaque samples. The concentrations of suPAR were determined in saliva and serum, and 18 microbial species and the immunoglobulin response to them was evaluated...
May 11, 2018: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29676806/obstacles-to-comprehensive-dental-care-in-patients-with-sustained-limitations-of-their-decision-making-abilities-findings-from-a-delphi-study
#2
Alessandra Blaizot, Céline Catteau, Caroline Delfosse, Olivier Hamel, Thomas Trentesaux
The objective of this study was to explore the therapeutic limitations experienced by a panel of special-care dentists in France when treating patients with sustained limitations of their decision-making abilities. We used a Delphi technique conducted in three rounds from 01 June 2014 to 30 September 2015. A first questionnaire comprising open-ended questions was addressed to 72 panellists. A content analysis of the returned questionnaires served to draft a second questionnaire comprising closed-ended questions; this was sent to the 28 panellists who responded in the first round...
April 20, 2018: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29676804/the-biphasic-effect-of-extracellular-glucose-concentration-on-carbachol-induced-fluid-secretion-from-mouse-submandibular-glands
#3
Momomi Terachi, Chikara Hirono, Michinori Kitagawa, Makoto Sugita
Cholinergic agonists evoke elevations of the cytoplasmic free-calcium concentration ([Ca2+ ]i ) to stimulate fluid secretion in salivary glands. Salivary flow rates are significantly reduced in diabetic patients. However, it remains elusive how salivary secretion is impaired in diabetes. Here, we used an ex vivo submandibular gland perfusion technique to characterize the dependency of salivary flow rates on extracellular glucose concentration and activities of glucose transporters expressed in the glands. The cholinergic agonist carbachol (CCh) induced sustained fluid secretion, the rates of which were modulated by the extracellular glucose concentration in a biphasic manner...
April 20, 2018: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29676511/role-of-the-high-mobility-group-box-1-signalling-axes-via-the-receptor-for-advanced-glycation-end-products-and-toll-like-receptor-4-in-the-immunopathology-of-oral-lichen-planus-a-potential-drug-target
#4
Abdelhakim Salem, Rabeia Almahmoudi, Mari Vehviläinen, Tuula Salo
High mobility group box 1 (HMGB1) is an extremely conserved DNA-binding protein that stabilizes nucleosomes and facilitates gene transcription in mammalian cells. When released extracellularly, HMGB1 becomes an alarmin that can mediate systemic diseases. High mobility group box 1 signals via two main receptors: receptor for advanced glycation end-products (RAGE) and toll-like receptor-4 (TLR4). We hypothesized that HMGB1 expression is increased in patients with oral lichen planus (OLP) relative to healthy controls...
April 20, 2018: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29676477/influence-of-estrogen-deficiency-on-guided-bone-augmentation-investigation-of-rat-calvarial-model-and-osteoblast-like-mc3t3-e1-cells
#5
Tatsuya Kubota, Akira Hasuike, Naoya Tsukune, Yasumasa Ozawa, Takanobu Yamamoto, Seiko Min, Masako Naito, Shuichi Sato
The effect of estrogen deficiency in bone augmentation, and the mechanisms by which estrogen deficiency impedes osteoblast differentiation and collagen matrix production, were examined. Twenty female Jcl:Wistar rats were divided into two groups: ovariectomized rats; and control rats. Guided bone augmentation was performed by positioning plastic caps in the calvarium of all animals at 8 wk after ovariectomy or sham surgery. Micro-computed tomography and histological sections were used to determine the amount of bone augmentation within the plastic caps...
April 20, 2018: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29664137/msh-homeobox-1-polymorphisms-and-the-risk-of-non-syndromic-orofacial-clefts-a-meta-analysis
#6
Min Gu, Yan Zhang, Hualian Liu, Jue Liu, Danxia Zhu, Xu Yang
MSH homebox 1 (MSX1) is a susceptibility gene for non-syndromic orofacial clefts (NSOCs). Here, a meta-analysis was conducted to assess their associations. A systematic search of PubMed to 1 September 2017, was performed to retrieve all eligible studies. Odds ratios (ORs) were used to calculate the associations. The stability of the results was evaluated by sensitivity analysis. Publication bias was assessed using Begg's funnel plots and the Egger test. In silico Msx1 expression during early mouse craniofacial development was evaluated by the Gene Expression Omnibus...
April 17, 2018: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29745471/dna-replication-licensing-factor-mcm2-geminin-and-ki67-define-proliferative-state-and-are-linked-with-survival-in-oral-squamous-cell-carcinoma
#7
Nadia Al-Hazmi, Turki Alhazzazi, Gareth Williams, Kai Stoeber, Raghad Al-Dabbagh
Oral squamous cell carcinoma (OSCC) is still an unabated global killer with little advancement in its survival rate. DNA replication licensing proteins and Aurora kinase A are biomarkers that play important roles in genomic stability. The expression profile of minichromosomal maintenance protein 2 (MCM2), Ki67, geminin, and Aurora-A were linked to clinicopathological and outcome parameters, survival, and DNA content in 125 cases of OSCC. Oral fibroepithelial polyps (OFEP) were controls. The OSCC tumour cells were in a rapidly proliferating state, as assessed by the increased expression profile of MCM2, Ki67, geminin, and Aurora-A and of the geminin/Ki67 ratio, and the decrease of the MCM2/Ki67 ratio, in OSCC compared with OFEP (P < 0...
June 2018: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29745470/author-guidelines
#8
(no author information available yet)
No abstract text is available yet for this article.
June 2018: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29517121/effects-of-three-%C3%AE-alkylidene-%C3%AE-lactams-on-the-formation-of-multispecies-biofilms
#9
Josiane de Almeida, Andrea L Pimenta, Ulisses A Pereira, Luiz C A Barbosa, Michel A Hoogenkamp, Suzette V van der Waal, Wim Crielaard, Wilson T Felippe
This study evaluated the inhibitory effects of lactams on Streptococcus mutans, Enterococcus faecalis, and Candida glabrata multispecies biofilm formation. γ-Alkylidene-γ-lactams 1, 2, and 3 [solubilized in 3.5% dimethyl sulfoxide (DMSO)] were tested. Glass coverslips were conditioned with either the lactams or 3.5% DMSO (control) for 1 h, inoculated with microbial cultures, and incubated for 48 h. To assess the effect of the lactams on biofilm formation, the following parameters were determined: the biofilm biomass (by both crystal violet staining and protein determination); the amount of insoluble polysaccharides of the extracellular matrix; and the number of viable and total cells [by both colony-forming unit counting and quantitative real-time PCR (qPCR)]...
June 2018: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29480521/soft-tissue-changes-following-extraction-vs-nonextraction-orthodontic-fixed-appliance-treatment-a-systematic-review-and-meta-analysis
#10
REVIEW
Dimitrios Konstantonis, Dimitrios Vasileiou, Spyridon N Papageorgiou, Theodore Eliades
The aim of this systematic review was to assess the effect of systematic extraction protocols during orthodontic fixed appliance treatment on the soft tissue profile of human patients. Nine databases were searched until December 2016 for controlled clinical studies including premolar extraction or nonextraction treatment. After elimination of duplicate studies, data extraction, and risk-of-bias assessment according to the Cochrane guidelines, random-effects meta-analyses of mean differences (MD) or standardized mean differences (SMD) and their 95% CIs were performed, followed by subgroup, meta-regression, and sensitivity analyses...
June 2018: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29512929/author-guidelines
#11
(no author information available yet)
No abstract text is available yet for this article.
April 2018: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29450917/factors-predictive-of-the-onset-and-duration-of-action-of-local-anesthesia-in-mandibular-third-molar-surgery-a-prospective-study
#12
Mohammad H Al-Shayyab, Zaid H Baqain
The aim of this study was to assess the influence of patients' and surgical variables on the onset and duration of action of local anesthesia (LA) in mandibular third-molar (M3) surgery. Patients scheduled for mandibular M3 surgery were considered for inclusion in this prospective cohort study. Patients' and surgical variables were recorded. Two per cent (2%) lidocaine with 1:100,000 epinephrine was used to block the nerves for extraction of mandibular M3. Then, the onset of action and duration of LA were monitored...
April 2018: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29424090/the-host-defense-peptide-ll-37-is-detected-in-human-parotid-and-submandibular-sublingual-saliva-and-expressed-in-glandular-neutrophils
#13
Daniel Svensson, Alexandra Aidoukovitch, Emma Anders, Birgitta Agerberth, Fredrik Andersson, Eva Ekblad, Dan Ericson, Daniel Nebel, Ulrikke Voss, Bengt-Olof Nilsson
The human host defense peptide, LL-37, is an important player in the first line of defense against invading microorganisms. LL-37 and its precursor, hCAP18, have been detected in unstimulated whole saliva but no reports showing hCAP18/LL-37 in isolated, parotid, and/or submandibular/sublingual saliva have been presented. Here, we measured the levels of hCAP18/LL-37 in human parotid and submandibular/sublingual saliva and investigated the expression of hCAP18/LL-37 in parotid and submandibular gland tissue. Parotid and submandibular/sublingual saliva was collected from healthy volunteers, and the levels of hCAP18/LL-37 in saliva were analyzed by dot blot, ELISA, and western blotting...
April 2018: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29411897/the-immunopathogenic-and-immunomodulatory-effects-of-interleukin-12-in-periodontal-disease
#14
REVIEW
Benjar Issaranggun Na Ayuthaya, Vincent Everts, Prasit Pavasant
Interleukin 12 (IL-12) is an inflammatory cytokine that promotes the response of the immune system. This cytokine has been implicated as a potent stimulator of several diseases characterized by inflammatory-induced bone destruction, such as rheumatoid arthritis and periodontitis. Yet, the exact role of IL-12 in the development and progress of periodontitis has not been clarified. Several studies have demonstrated a positive correlation between the level of IL-12 and the severity of periodontal destruction. Deletion of IL-12 in mice with periodontitis significantly suppressed the level of bone destruction...
April 2018: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29392764/genuine-halitosis-in-patients-with-dental-and-laryngological-etiologies-of-mouth-odor-severity-and-role-of-oral-hygiene-behaviors
#15
Sabina Herman, Grażyna Lisowska, Joanna Herman, Ewa Wojtyna, Maciej Misiołek
The aims of the study were to determine the severity of halitosis and the association between oral hygiene practices and the severity of malodor in patients with dental and laryngological etiologies of genuine halitosis. Thirty-five laryngological and 40 dental patients with halitosis completed a structured interview and underwent laryngological and dental examinations. Halitosis was assessed using organoleptic and halimeter tests. Greater halitosis severity in laryngological patients was associated with worse clinical status of the palatine tonsils, less frequent toothbrushing, less frequent use of tongue cleaners, fewer daily meals, and increased use of mouthrinses...
April 2018: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29380895/use-of-polyphenols-as-a-strategy-to-prevent-bond-degradation-in-the-dentin-resin-interface
#16
Isabel C C M Porto, Ticiano G Nascimento, José M S Oliveira, Pedro H Freitas, Asmaa Haimeur, Rodrigo França
This study evaluated the effect of dentin pretreatment with the polyphenols quercetin and resveratrol on the resin-dentin microtensile bonding strength (μTBS) and collagen fibrils stability of the adhesive interface. Different concentrations (100, 250, 500, or 1,000 μg ml-1 ) of quercetin or resveratrol, or a mixture of quercetin and resveratrol (3:1, 1:1, 1:3; vol:vol), as well as distilled water or 2% chlorhexidine digluconate, were applied to etched dentin. Then, a two-step etch-and-rinse adhesive was applied followed by composite restoration...
April 2018: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29377334/effect-of-finish-line-design-on-stress-distribution-in-bilayer-and-monolithic-zirconia-crowns-a-three-dimensional-finite-element-analysis-study
#17
Shoko Miura, Shin Kasahara, Shinobu Yamauchi, Hiroshi Egusa
This study evaluated the influence of different finish line designs and abutment materials on the stress distribution of bilayer and monolithic zirconia crowns using three-dimensional finite element analysis (FEA). Three-dimensional models of two types of zirconia premolars - a yttria-stabilized zirconia framework with veneering ceramic and a monolithic zirconia ceramic - were used in the analysis. Cylindrical models with the finish line design of the crown abutments were prepared with three types of margin curvature radius (CR): CR = 0 (CR0; shoulder margin), CR = 0...
April 2018: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29336070/changes-in-surface-characteristics-of-titanium-and-zirconia-after-surface-treatment-with-ultraviolet-light-or-non-thermal-plasma
#18
Anders Henningsen, Ralf Smeets, Roman Heuberger, Ole T Jung, Henning Hanken, Max Heiland, Claudio Cacaci, Clarissa Precht
Positive effects of irradiation with ultraviolet (UV) light or treatment with non-thermal plasma on titanium and zirconia surfaces have been described in various studies. The aim of this study was to assess and compare the changes in the physicochemical surface conditions of titanium and zirconia surfaces after a short treatment with UV light or with non-thermal plasmas of argon or oxygen. Titanium and zirconia samples with moderately rough surfaces were treated for 12 min either in a UV-light oven or in a non-thermal plasma reactor that generates non-thermal plasmas of oxygen or argon...
April 2018: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29334137/calcium-phosphate-precipitation-in-experimental-gaps-between-fluoride-containing-fast-setting-calcium-silicate-cement-and-dentin
#19
Bahram Ranjkesh, Ming Ding, Michel Dalstra, Jens R Nyengaard, Jacques Chevallier, Flemming Isidor, Henrik Løvschall
A novel fast-setting calcium silicate cement containing fluoride (novel-CSC) has been developed for applications in tooth crowns. The aim of this study was to assess the ability of the novel-CSC to close the experimental gaps at the dentin-cement interface. The novel-CSC was tested against Vitrebond and GC Fuji II LC. Experimental gaps of 50 or 300 μm width were created between the materials and dentin. Specimens with the 300-μm-wide gap were immersed in phosphate-buffered saline and the closed gap area was measured during 96 h...
April 2018: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29327785/the-effect-of-partially-exposed-connective-tissue-graft-on-root-coverage-outcomes-a-systematic-review-and-meta-analysis
#20
REVIEW
Austin Dodge, Jeffrey Garcia, Paul Luepke, Yu-Lin Lai, Moawia Kassab, Guo-Hao Lin
The aim of this systematic review was to compare the root-coverage outcomes of using a partially exposed connective tissue graft (CTG) technique with a fully covered CTG technique for root coverage. An electronic search up to February 28th , 2017, was performed to identify human clinical studies with data comparing outcomes of root coverage using CTG, with and without a partially exposed graft. Five clinical studies were selected for inclusion in this review. For each study, the gain of keratinized gingiva, reduction of recession depth, number of surgical sites achieving complete root coverage, percentage of root coverage, gain of tissue thickness, and changes of probing depth and clinical attachment level were recorded...
April 2018: European Journal of Oral Sciences
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