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European Journal of Oral Sciences

Pinar Altinci, Murat Mutluay, Leo Tjäderhane, Arzu Tezvergil-Mutluay
Matrix metalloproteinases (MMPs) and cysteine cathepsins (CCs) can break down unprotected type I collagen fibrils in dentin matrix. This study investigated the use of potassium fluoride (KF) as a potential inhibitor of MMPs and CCs in dentin. Demineralized dentin beams were divided into groups (n = 10 in each group) and incubated in artificial saliva (AS, control), either alone or with one of seven concentrations of KF (6-238 mM fluoride) for 1, 7, and 21 d. After 21 d, all groups were further aged in AS for 6 months...
November 10, 2018: European Journal of Oral Sciences
Ida S R Stenhagen, Håkon V Rukke, Inger S Dragland, Hilde M Kopperud
The lifespan of a resin-based restoration is limited, with the main reason for failure being secondary caries. Biofilm formation at the tooth-material interface is a necessary etiological agent for caries development. Dental materials with antimicrobial properties may reduce formation of biofilm and thus increase the longevity of restorations. This study aimed to investigate the effect of methacrylated chitosan (CH-MA), incorporated into the polymeric network of an experimental dental composite and adhesive, on biofilm growth of Streptococcus mutans and to assess the mechanical properties of the modified materials...
November 9, 2018: European Journal of Oral Sciences
Gustavo G Nascimento, Bo Danielsen, Vibeke Baelum, Rodrigo Lopez
We used novel analytical approaches to identify inflammatory response patterns to plaque accumulation in experimental gingivitis studies in humans. Data from two experimental gingivitis studies [Dataset I (n = 40) and Dataset II (n = 42)], which differed in design and recording methods, were used. Both studies comprised a three-phase program as follows: pre-induction period (oral hygiene as usual for Dataset I; professional tooth cleaning for Dataset II); induction period (plaque accumulation); and resolution period (oral hygiene as usual)...
November 9, 2018: European Journal of Oral Sciences
Jarin Paphangkorakit, Kasama Kanpittaya, Nattawipa Pawanja, Waranuch Pitiphat
Fast eating has been shown to increase the risk of overweight in both children and adults. The objectives of the present study were to investigate the correlation between chewing rate and the number of chews per mouthful and to evaluate if they were associated with the weight of meal intake. Thirty healthy subjects, aged 18-24 yr, ate a test lunch at their habitual speed until they felt satiated. The activities of masseter and suprahyoid muscles were recorded to determine the number of chews and the moment of swallowing...
October 31, 2018: European Journal of Oral Sciences
Harry C Stamatakis, Ralph Steegman, Joost Dusseldorp, Yijin Ren
Head position during cone beam computed tomography (CBCT) examination can easily deviate from the ideal, which may affect the accuracy of the segmented three-dimensional (3D) model. The aim of this study was to determine the effect of head positioning on the accuracy of the 3D model. A human dry skull was positioned at predetermined orientations in a CBCT scanner and scanned in multiple orientations and voxel sizes. The resulting 3D surface models were superimposed over those derived from the reproducible centered positioned skull with 0° inclination...
October 30, 2018: European Journal of Oral Sciences
Sergio M Viafara-Garcia, Diego F Gualtero, Daniel Avila-Ceballos, Gloria I Lafaurie
Eikenella corrodens is a gram-negative bacterium, and although primarily associated with periodontal infections or infective endocarditis, it has been identified in coronary atheromatous plaques. The effect of its lipopolysaccharide (LPS) on human coronary artery endothelial cells (HCAECs) is unknown. Our aim was to examine the mechanism underlying the inflammatory response in HCAECs stimulated with E. corrodens-LPS and to evaluate monocyte adhesion. Endothelial responses were determined by measuring the levels of chemokines and cytokines using flow cytometry...
October 24, 2018: European Journal of Oral Sciences
Xin Liu, Chunkui Zhang, Qian Liu, Kaixiang Zhou, Nannan Yin, Hongyun Zhang, Minghong Shi, Xiaodong Liu, Meiqing Wang
Unilateral anterior crossbite (UAC) has been demonstrated to cause masseter hyperactivity via the periodontal trigeminal mesencephalic nucleus (Vme)-trigeminal motor nucleus circuit. Here, we studied activation of motor neurons of the facial nucleus (VII), hypoglossal nucleus (XII), nucleus ambiguus (Amb), and spinal nucleus of the accessory nerve (SNA) in rats with UAC via their similar connections with Vme. An anterograde tracer, biotinylated dextran amine (BDA), was injected into the Vme to identify the central axon terminals around the motor neurons of VII, XII, Amb, and SNA...
October 20, 2018: European Journal of Oral Sciences
Petra Borilova Linhartova, Julius Janos, Simona Slezakova, Jirina Bartova, Jitka Petanova, Pavel Kuklinek, Antonin Fassmann, Ladislav Dusek, Lydie Izakovicova Holla
Genetic factors, especially those related to immune system functioning, have been intensively studied to determine their role in the development of recurrent aphthous stomatitis (RAS). The aim of the present study was to analyze gene variability in interleukin (IL)2, IL4 (and its receptor α, IL4Rα), IL10, and IL13, which were selected based on literature review and/or their functional relevance, in Czech patients with RAS and in healthy controls. In total, 252 subjects (178 controls and 74 patients with RAS) were enrolled in this case-control study, and their detailed anamnestic, clinical, and laboratory data were obtained...
October 20, 2018: European Journal of Oral Sciences
Anja W Dynesen, Charlotte A Gehrt, Sabine E Klinker, Lisa B Christensen
It is well known that early signs of eating disorders (EDs), such as dental erosion and enlarged salivary glands, may be recognized in the dental clinic. Dentists acknowledge that approaching a patient to discuss the suspicion of an ED is difficult. However, little is known about how persons with EDs experience and manage dental visits. Therefore, this study aimed to uncover knowledge, experience, and attitude of oral health and oral health behavior among persons with EDs. The study design was cross-sectional and 260 persons with EDs completed an electronic questionnaire...
October 19, 2018: European Journal of Oral Sciences
Bjørn E Dahl, Jon E Dahl, Hans J Rønold
The present study used a new, digitized version of the impression replica technique, namely the dual-scan technique, to evaluate the adaptation of single-crown fixed dental prostheses (FDPs). Scans of the bare master model and of the master model with a silicone layer representing the cement layer were superimposed and analyzed using designated software. Single crowns produced using the lost-wax metal casting technique were included. The cement space of the band width, 0.5-1.0 mm from the preparation margin (marginal fit), was smallest for crowns made from laser-sintered cobalt-chromium...
October 8, 2018: European Journal of Oral Sciences
Anna Lövgren, Linnea Karlsson Wirebring, Birgitta Häggman-Henrikson, Anders Wänman
Temporomandibular disorders (TMDs) are common, but many patients with such disorders go undetected and under-treated. Our aim was to evaluate the outcome of using a screening tool (5 yr after it was first implemented), on the clinical decision-making for patients with TMDs. Adults who attended for a dental check-up at the Public Dental Health Services in Västerbotten, Sweden, answered three screening questions (3Q/TMD) on frequent jaw pain, pain on jaw function, and catching/locking of the jaw. The dental records of a random sample of 200 individuals with at least one positive response to 3Q/TMD (3Q screen-positive patients) and 200 individuals with all negative responses (3Q screen-negative patients) were reviewed for TMD-related treatment decisions...
October 8, 2018: European Journal of Oral Sciences
Kosuke Kusaba, Futoshi Komine, Junichi Honda, Kei Kubochi, Hideo Matsumura
This study investigated the effect of preparation design on the marginal and internal adaptation of laminate veneers (LVs) fabricated from translucent zirconia. Thirty-three resin teeth were prepared for LVs of three designs: window preparation (WP); incisal shoulder preparation (ISP); and incisal palatal chamfer preparation (IPP). Marginal adaptation was evaluated by measuring the vertical discrepancy between the LV margin and the finish line at 60 points. The internal adaptation was assessed by measuring the internal space width as the distance between the LV and the tooth at cervical, central, and incisal sites after sectioning...
October 5, 2018: European Journal of Oral Sciences
Guido Sterzenbach, Martin Rosentritt, Hendrik Meyer-Lueckel, Kerstin Bitter, Michael Naumann
The influence of a fiber post-restored abutment tooth on the load capability of a three-unit zirconia framework cantilever fixed dental prosthesis (cFDP) was evaluated after simulated clinical function. Human lower sound premolars (n = 64) were distributed, in equal numbers, to four experimental groups: two vital abutment teeth (group I; control); mesial abutment tooth post-restored (group II); distal abutment tooth post-restored (group III); and mesial and distal abutment teeth post-restored (group IV). All specimens received an adhesively luted three-unit cFDP of veneered zirconia...
October 1, 2018: European Journal of Oral Sciences
Sou Nakazaki, Kazuya Tadokoro, Shiori Takehana, Yumiko Syoji, Yoshihito Shimazu, Mamoru Takeda
The present study investigated whether daily systemic administration of docosahexaenoic acid (DHA) in rats could attenuate the hyperexcitability of trigeminal spinal nucleus caudalis (SpVc) neurons associated with hyperalgesia. Inflammation was induced in rats by injecting complete Freund's adjuvant into the whisker pads. The threshold of escape from mechanical stimulation applied to the whisker pads in inflamed rats was significantly lower than that in naïve rats. The lowered mechanical threshold in the inflamed rats was returned to that in naïve rats by 3 d intraperitoneal administration of DHA...
October 1, 2018: European Journal of Oral Sciences
Tamar Brosh, Zvi Metzger, Raphael Pilo
The circumferential strains created in the radicular dentin by nickel-titanium (NiTi) and stainless steel (SS) finger spreaders (FSs) during a simulated clinical procedure of lateral compaction were compared after minimal (size 50) and extensive (size 100) canal preparations. Nineteen maxillary central incisors underwent minimal preparation, while 10 underwent an extra phase of extensive preparation. Four miniature strain gauges were bonded circumferentially in the apical third of the root (buccal, lingual, mesial, and distal)...
September 25, 2018: European Journal of Oral Sciences
Heithem Ben Amara, Hyun Y Song, Eunju Ryu, Ji S Park, Frank Schwarz, Byeong M Kim, Bong-Kyu Choi, Ki-Tae Koo
This study aimed to verify, in in vivo settings, whether quorum-sensing inhibition molecules could attenuate alveolar bone loss induced by Porphyromonas gingivalis/Fusobacterium nucleatum co-infection and reduce the bacterial colonization of periodontal tissues. In BALB/c mice, periodontitis was induced through oral inoculation with P. gingivalis and F. nucleatum six times during a 42-d period. Quorum sensing inhibitors (a furanone compound and D-ribose) were administered simultaneously with bacterial infection...
September 19, 2018: European Journal of Oral Sciences
Pamela Uribe, Pawel Plakwicz, Lena Larsson, Ewa Czochrowska, Anna Westerlund, Maria Ransjö
We sought to investigate site-specific expression of bone-regulatory factors expressed by human dental follicles and to compare the stimulated expression of tumour necrosis factor (ligand) superfamily, member 11/tumour necrosis factor receptor superfamily, member 11b (RANKL/OPG) in human dental follicle cells (HDFCs) from different patients. Analysis of bone-regulatory markers in follicles from 12 different study participants was performed using RT-qPCR and immunofluorescence; apical and coronal segments from each dental follicle were processed independently...
September 14, 2018: European Journal of Oral Sciences
Leng Wu, Lei Zhao, Jun Wang, Chengcheng Liu, Yan Li, Yafei Wu
Bacterial metabolism during infection is related to bacterial persistence and virulence factors. Porphyromonas gingivalis is a key pathogen that contributes to chronic periodontitis. Our previous study showed that pckA, the gene encoding phosphoenolpyruvate carboxykinase, is a putative-specific pathogenic gene of virulent strains of P. gingivalis. Here, a pckA-deficient strain (ΔPG1676) was constructed in P. gingivalis W83. Virulence properties were compared between the mutant and wild-type strains. Specifically, hemagglutination activity was determined by the ability to agglutinate sheep erythrocytes...
August 20, 2018: European Journal of Oral Sciences
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December 2018: European Journal of Oral Sciences
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December 2018: European Journal of Oral Sciences
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