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Skin Research and Technology

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https://www.readbyqxmd.com/read/27896851/quantitating-the-lateral-skin-stiffness-by-a-new-and-versatile-electro-mechanical-instrument-preliminary-studies
#1
M Nomura, D Velleman, J Pierre, F Flament
BACKGROUND: A new electro-mechanical device for measuring the lateral stiffness of the skin is now available. It basically allows to recording the forces that the skin opposes to a lateral displacement (1-2 mm) of a pinching type movement. Preliminary assays of this device to various skin sites and an artificial substrate aimed at defining its major characteristics (sensitivity, reproducibility, variations according to skin site). METHODS: The calibration of the device (Khelometer(®) ) and assessment of its reproducibility were carried out through the use of elastometer substrates of various stiffness's...
November 29, 2016: Skin Research and Technology
https://www.readbyqxmd.com/read/27892649/thresholding-methods-for-lesion-segmentation-of-basal-cell-carcinoma-in-dermoscopy-images
#2
R Kaur, R LeAnder, N K Mishra, J R Hagerty, R Kasmi, R J Stanley, M E Celebi, W V Stoecker
PURPOSE: Algorithms employed for pigmented lesion segmentation perform poorly on dermoscopy images of basal cell carcinoma (BCC), the most common skin cancer. The main objective was to develop better methods for BCC segmentation. METHODS: Fifteen thresholding methods were implemented for BCC lesion segmentation. We propose two error metrics that better measure the type II error: Relative XOR Error and Lesion Capture Ratio. RESULTS: On training/test sets of 305 and 34 BCC images, respectively, five new techniques outperform two state-of-the-art methods used in segmentation of melanomas, based on the new error metrics...
November 28, 2016: Skin Research and Technology
https://www.readbyqxmd.com/read/27891678/morphomechanics-of-dermis-a-method-for-non-destructive-testing-of-collagenous-tissues
#3
R G Shah, M C Pierce, F H Silver
BACKGROUND: Collagenous tissues store, transmit and dissipate elastic energy during mechanical deformation. In skin, mechanical energy is stored during loading and then is dissipated, which protects skin from mechanical failure. Thus, energy storage (elastic properties) and dissipation (viscous properties) are important characteristics of extracellular matrices (ECMs) that support the cyclic loading of ECMs without tissue failure. METHODS: Uniaxial stress-strain measurements on decellularized human dermis have been made and compared to results of a non-destructive technique involving optical coherence tomography (OCT) combined with vibrational analysis...
November 27, 2016: Skin Research and Technology
https://www.readbyqxmd.com/read/27885713/a-new-tool-to-quantify-the-geometrical-characteristics-of-facial-skin-pores-changes-with-age-and-a-making-up-procedure-in-caucasian-women
#4
A Shaiek, F Flament, G François, V Lefebvre-Descamps, C Barla, M Vicic, F Giron, R Bazin
BACKGROUND: Facial skin pores (FSP) are common and benign signs that generate frequent esthetic concerns or complaints. Despite their worldwide prevalence, related literature remains scarce. Hence, a new device has been developed and applied to validating studies, aiming at best describing FSP as they are self-perceived, i.e. their anatomic features, their possible alterations with age and their appearance after application of a make-up product. METHODS: Dermascore+(®) is an imaging device dedicated to a direct observation and acquisition of various characteristics of the skin surface...
November 25, 2016: Skin Research and Technology
https://www.readbyqxmd.com/read/27882608/about-the-in-vivo-quantitation-of-skin-anisotropy
#5
C Rosado, F Antunes, R Barbosa, R Fernando, M Estudante, H N Silva, L M Rodrigues
BACKGROUND/PURPOSE: Human skin anisotropy is difficult to quantify. The Cutiscan(®) , is allegedly, the first biometrical system to provide information on the elastic and viscoelastic properties, as well as on anisotropy and directionality of the human skin in vivo. Thus, this study aims to contribute to characterize this new device and its applicability, and to compare its behavior with two other well-known devices-the Cutometer(®) and the Reviscometer(®) . METHODS: Measurements were conducted with each device in three different anatomical sites (forehead, forearm and leg) of 20 female volunteers engaged after informed consent...
November 24, 2016: Skin Research and Technology
https://www.readbyqxmd.com/read/27878858/non-invasive-tools-for-the-diagnosis-of-cutaneous-melanoma
#6
REVIEW
C Fink, H A Haenssle
BACKGROUND: While the excisional biopsy and histological examination of suspicious lesions remains the current gold standard for diagnosing cutaneous melanoma (CM), there is a demand for more objective and non-invasive examination methods that may support clinicians in their decision when to biopsy or not. METHODS: This review is based on publications and guidelines retrieved by a selective search in PubMed and MEDLINE and focused on non-invasive diagnostic strategies for detecting melanoma...
November 22, 2016: Skin Research and Technology
https://www.readbyqxmd.com/read/27878850/analysis-of-morphological-changes-after-facial-massage-by-a-novel-approach-using-three-dimensional-computed-tomography
#7
H Nishimura, I Okuda, N Kunizawa, T Inoue, Y Nakajima, S Amano
BACKGROUND/PURPOSE: Photograph-based visual scoring has been used for evaluation of facial morphological changes. Here, we describe a three-dimensional computed tomography (3D-CT) method for objective analysis of facial and intra-facial (subcutaneous) changes. The effects of facial massage were examined using both methods. METHODS: Subjects were 12 healthy female volunteers without facial scars or deformation (age 30-54 years, mean 39.4 years). Photograph-based scoring of massage-induced morphological changes was done at the nasolabial folds, upper, lower and lateral cheeks and lower eyelids...
November 22, 2016: Skin Research and Technology
https://www.readbyqxmd.com/read/27873364/modelling-the-effect-of-hydration-on-skin-conductivity
#8
L Davies, P Chappell, T Melvin
BACKGROUND: Electrical signals are recorded from and sent into the body via the skin in a number of applications. In practice, skin is often hydrated with liquids having different conductivities so a model was produced in order to determine the relationship between skin impedance and conductivity. METHODS: A model representing the skin was subjected to a variety of electrical signals. The parts of the model representing the stratum corneum were given different conductivities to represent different levels of hydration...
November 22, 2016: Skin Research and Technology
https://www.readbyqxmd.com/read/27868283/non-invasive-evaluation-of-skin-tension-lines-with-elastic-waves
#9
C Deroy, M Destrade, A Mc Alinden, A Ní Annaidh
BACKGROUND: Since their discovery by Karl Langer in the 19th Century, Skin Tension Lines (STLs) have been used by surgeons to decide the location and orientation of an incision. Although these lines are patient-specific, most surgeons rely on generic maps to determine their orientation. Beyond the imprecise pinch test, there remains no accepted method for determining STLs in vivo. METHODS: (i) The speed of an elastic motion travelling radially on the skin of canine cadavers was measured with a commercial device called the Reviscometer(®) ...
November 20, 2016: Skin Research and Technology
https://www.readbyqxmd.com/read/27868246/personal-identification-based-on-skin-texture-features-from-the-forearm-and-multi-modal-imaging
#10
F Bianconi, E Chirikhina, F Smeraldi, C Bontozoglou, P Xiao
BACKGROUND/PURPOSE: We investigate the use of skin texture features from the inner forearm as a means for personal identification. The forearm offers a number of potential advantages in that it is a fairly accessible area, and, compared with other zones such as fingertips, is less exposed to the elements and more shielded from wear. METHODS: We extract and combine skin textural features from two imaging devices (optical and capacitive) with the aim of discriminating between different individuals...
November 20, 2016: Skin Research and Technology
https://www.readbyqxmd.com/read/27868243/simulation-of-laser-tattoo-pigment-interaction-in-a-tissue-mimicking-phantom-using-q-switched-and-long-pulsed-lasers
#11
K J Ahn, B J Kim, S B Cho
BACKGROUND: Laser therapy is the treatment of choice in tattoo removal. However, the precise mechanisms of laser-tattoo pigment interactions remain to be evaluated. METHODS: We evaluated the geometric patterns of laser-tattoo pigment particle interactions using a tattoo pigment-embedded tissue-mimicking (TM) phantom. RESULTS: A Q-switched (QS) neodymium-doped yttrium aluminum garnet laser was used at settings of 532-, 660-, and 1064-nm wavelengths, single-pulse and quick pulse-to-pulse treatment modes, and spot sizes of 4 and 7 mm...
November 20, 2016: Skin Research and Technology
https://www.readbyqxmd.com/read/27868242/assessment-of-macrovascular-endothelial-function-using-pulse-wave-analysis-and-its-association-with-microvascular-reactivity-in-healthy-subjects
#12
N N I N Ibrahim, A H G Rasool
BACKGROUND: Pulse wave analysis (PWA) and laser Doppler fluximetry (LDF) are non-invasive methods of assessing macrovascular endothelial function and microvascular reactivity respectively. The aim of this study was to assess the correlation between macrovascular endothelial function assessed by PWA and microvascular reactivity assessed by LDF. METHOD: 297 healthy and non-smoking subjects (159 females, mean age (±SD) 23.56 ± 4.54 years) underwent microvascular reactivity assessment using LDF followed by macrovascular endothelial function assessments using PWA...
November 20, 2016: Skin Research and Technology
https://www.readbyqxmd.com/read/27868241/high-intensity-focused-ultrasound-treatment-for-skin-ex-vivo-evaluation
#13
J-H Park, S-D Lim, S H Oh, J H Lee, U C Yeo
BACKGROUND/PURPOSE: High-intensity focused ultrasound (HIFU) has been used for skin tightening. However, there is a rising concern of irreversible adverse effects. Our aim was to evaluate the depth of thermal injury zone after HIFU energy passes through different condition. MATERIALS AND METHODS: To analyze the consistency of the HIFU device, phantom tests were performed. Simulations were performed on ex vivo porcine tissues to estimate the area of the thermal coagulation point (TCP) according to the applied energy and skin condition...
November 20, 2016: Skin Research and Technology
https://www.readbyqxmd.com/read/27868233/age-related-changes-in-dermal-fiber-like-structures-in-facial-cheeks
#14
K Mizukoshi, K Hirayama
BACKGROUND/PURPOSE: Despite recent progress in non-invasive measurement methods, such as in vivo laser confocal microscopy (CLSM), it is difficult to quantitatively measure age-related changes in dermal fibrous structures in the face using these methods and qualitative characteristics. We used characteristics extracted from the analysis of CLSM images to quantitatively investigate the effects of aging on dermal fibrous structures in the face. METHODS: CLSM images of dermal fibrous structures were obtained from 90 Japanese females, ranging in age from 20 to 60 years...
November 20, 2016: Skin Research and Technology
https://www.readbyqxmd.com/read/27804169/structural-and-functional-3d-mapping-of-skin-tumours-with-non-invasive-multispectral-optoacoustic-tomography
#15
S Y Chuah, A B E Attia, V Long, C J H Ho, P Malempati, C Y Fu, S J Ford, J S S Lee, W P Tan, D Razansky, M Olivo, S Thng
BACKGROUND: Recent advances in technology have enabled the development of various non-invasive skin imaging tools to aid real-time diagnosis of both benign and malignant skin tumours, minimizing the need for invasive skin biopsy. Multispectral optoacoustic tomography (MSOT) is a recently developed non-invasive imaging tool, which offers the unique capacity for high resolution three dimensional (3D) optical mapping of tissue by further delivering highly specific optical contrast from a depth of several millimetres to centimetres in living tissues...
November 2, 2016: Skin Research and Technology
https://www.readbyqxmd.com/read/27800641/automatic-facial-pore-analysis-system-using-multi-scale-pore-detection
#16
J Y Sun, S W Kim, S H Lee, J E Choi, S J Ko
BACKGROUND/PURPOSE: As facial pore widening and its treatments have become common concerns in the beauty care field, the necessity for an objective pore-analyzing system has been increased. Conventional apparatuses lack in usability requiring strong light sources and a cumbersome photographing process, and they often yield unsatisfactory analysis results. This study was conducted to develop an image processing technique for automatic facial pore analysis. METHODS: The proposed method detects facial pores using multi-scale detection and optimal scale selection scheme and then extracts pore-related features such as total area, average size, depth, and the number of pores...
November 1, 2016: Skin Research and Technology
https://www.readbyqxmd.com/read/27800639/measurement-of-skin-surface-biomakers-by-transdermal-analyses-patch-following-different-in-vivo-models-of-irritation-a-pilot-study
#17
D Falcone, P Spee, K Salk, M Peppelman, P C M van de Kerkhof, P E J van Erp
BACKGROUND/PURPOSE: FibroTx Transdermal Analyses Patch (TAP) is a novel technology for non-invasive measurements of protein biomarkers on the skin surface, in vivo. The aim of this study was to explore the potential of TAP in detecting skin surface biomarkers following mild perturbations, in vivo, using two experimental models: tape stripping, mimicking acute barrier disruption, and histamine iontophoresis, mimicking acute and local inflammation at minimal skin barrier insult. METHODS: Tape stripping and histamine iontophoresis were performed in two separate experiments on the volar forearm of healthy volunteers (n = 27 and n = 10, respectively)...
November 1, 2016: Skin Research and Technology
https://www.readbyqxmd.com/read/27800637/effect-of-aging-on-breast-skin-thickness-and-elasticity-implications-for-breast-support
#18
C E Coltman, J R Steele, D E McGhee
BACKGROUND/PURPOSE: The skin overlying a woman's breast acts as an anatomical support structure to the breast. Although aging is known to affect the thickness and elasticity of human skin, limited research has examined age-related changes to skin covering the breast or related these changes to breast support requirements. The purpose of this study was to determine the effect of age on female breast skin thickness and elasticity. METHODS: The left breast of 339 women (18-84 years), classified into four age groups (18-24 years, 25-44 years, 45-64 years, and 65 + years), was divided into four quadrants...
November 1, 2016: Skin Research and Technology
https://www.readbyqxmd.com/read/27796065/clinical-and-color-doppler-ultrasound-evaluation-of-polyacrylamide-injection-in-hiv-patients-with-severe-facial-lipoatrophy-secondary-to-antiretroviral-therapy
#19
E Faundez, N Vega, E Vera, P Vega, D Sepulveda, X Wortsman
BACKGROUND/PURPOSE: Facial lipoatrophy in HIV patients, secondary to antiretroviral therapy (ART) with thymidine analogs, has been related to important psychosocial alterations and poor adherence to treatment. Polyacrylamide gel (PAAG) is a filler that has been used for treating facial lipoatrophy in HIV patients. The aim was to assess the clinical and sonographic anatomical changes after injection of PAAG in HIV patients with facial lipoatrophy secondary to ART. METHODS: HIV patients receiving ART and suffering from severe facial lipoatrophy were recruited and underwent clinical and color Doppler ultrasound evaluation prior to PAAG application (AQUAMID(®) ) and sonographically monitored at 18 months and clinically followed up for 36 months after the procedure...
October 30, 2016: Skin Research and Technology
https://www.readbyqxmd.com/read/27796064/measurements-of-scar-properties-by-skinfibrometer-%C3%A2-skinglossmeter-%C3%A2-and-mexameter-%C3%A2-and-comparison-with-vancouver-scar-scale
#20
S R Seo, N O Kang, M S Yoon, H J Lee, D H Kim
BACKGROUND: An objective measurement of scar is important for evaluating treatment outcomes. However, to date, there is no 'gold standard' for quantitative measurement of properties of hypertrophic scar. Existing objective modalities are neither portable nor easy to use. OBJECTIVE: This study aims to validate the correlation between objective measurements with SkinFibrometer(®) , SkinGlossMeter(®) , and Mexameter(®) and subjective assessment with Vancouver Scar Scale (VSS) of keloid and hypertrophic scar...
October 30, 2016: Skin Research and Technology
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