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Skin Research and Technology

U Dahlstrand, R Sheikh, C D Nguyen, J Hult, N Reistad, M Malmsjö
OBJECTIVE: A novel extended-wavelength diffuse reflectance spectroscopy (EWDRS) technique is being developed for future clinical non-invasive tumor margin delineation. In this study, the ability of EWDRS to identify the margins of pigmented skin lesions in an in vivo pig model was evaluated. MATERIALS AND METHODS: Extended-wavelength diffuse reflectance spectroscopy recordings (350-1550 nm) were made on 13 pigmented skin lesions and non-pigmented skin, as a reference...
May 17, 2018: Skin Research and Technology
K Lee, M Kim, K Kim
BACKGROUND: Skin surface evaluation has been studied using various imaging techniques. However, all these studies had limited impact because they were performed using visual exam only. To improve on this scenario with haptic feedback, we propose 3D reconstruction of the skin surface using a single image. Unlike extant 3D skin surface reconstruction algorithms, we utilize the local texture and global curvature regions, combining the results for reconstruction. MATERIALS AND METHODS: The first entails the reconstruction of global curvature, achieved by bilateral filtering that removes noise on the surface while maintaining the edge (ie, furrow) to obtain the overall curvature...
May 11, 2018: Skin Research and Technology
W Fei, S Xu, J Ma, W Zhai, S Cheng, Y Chang, X Wang, J Gao, H Tang, S Yang, X Zhang
BACKGROUND: Skin blood flow is believed to link with many diseases, and shows a significant heterogeneity. There are several papers on basal cutaneous microcirculation perfusion in different races, while the data in Chinese is vacant. OBJECTIVE: The aim was to establish the database of absolute fundamental supply of skin blood flow in the Chinese Han population. METHODS: With a full-field laser perfusion imager (FLPI), the skin blood flow can be quantified...
May 8, 2018: Skin Research and Technology
J Zundel, S A Ansari, H M Trivedi, J G Masters, S Mascaro
BACKGROUND: The purpose of this research is to characterize the effects of mouthwash solutions on oral friction and moisture using a quantitative in vitro approach. MATERIALS AND METHODS: The frictional coefficient of in vitro porcine tongue samples was measured using a magnetic levitation haptic device equipped with a custom tactor designed to mimic human skin. A commercially available moisture meter was used to measure moisture content of the samples. Tongue samples were first tested before treatment, then after application of saliva (either human or artificial), and again after application of 1 of 11 different mouthwash solutions...
May 7, 2018: Skin Research and Technology
C Martinez-Mera, F Alfageme Roldán, D Suarez Massa, G Roustan Gullón
No abstract text is available yet for this article.
May 7, 2018: Skin Research and Technology
M Fąk, H Rotsztejn, A Erkiert-Polguj
BACKGROUND: Microdermabrasion is a popular form of mechanical peel, used for many aesthetic purposes. Because it removes the superficial epidermal layer, it has an impact on hydrolipid skin coat. OBJECTIVE: The aim of the study was to examine the changes taking place in the hydrolipid coat of the skin after microdermabrasion measured by skin hydration and sebum level. METHODS: Sixteen healthy women were included in the study, and the aluminium oxide crystal microdermabrasion device was used over the entire face of each patient...
May 7, 2018: Skin Research and Technology
J Olsen, F H Birch-Johansen, L Themstrup, J Holmes, G B E Jemec
BACKGROUND: Dynamic optical coherence tomography (D-OCT) is a noninvasive imaging technique providing images of the skin and detecting movement in the tissue ie, measuring blood flow. The "attenuation coefficient" describes light absorption and scattering abilities of the tissue, while the dynamic signal provides a quantitative measure of the blood flow. AIM: The study objective is to describe the dynamic changes of the skin and skin vessels during histamine release using D-OCT...
May 1, 2018: Skin Research and Technology
N Ogai, I Nonaka, Y Toda, T Ono, S Minegishi, A Inou, M Hachiya, H Fukamizu
BACKGROUND: The intradermal (ID) route for vaccination represents an effective alternative to subcutaneous (SC)/intramuscular administration to induce protective immunity. However, a critical issue associated with ID vaccination is the precise delivery of solution in the upper dermis, which ensures enhanced immunity. METHODS: We fabricated a hollow microneedle unit made of poly-glycolic acid by injection molding and bonding, and created a dedicated prototype injector...
April 29, 2018: Skin Research and Technology
T Suzuki, T Uchino, I Hatta, Y Miyazaki, S Kato, K Sasaki, Y Kagawa
BACKGROUND: The aim of this study was to investigate whether the lamellar and lateral structure of intercellular lipid of stratum corneum (SC) can be evaluated from millimeter-sized SC (MSC) by X-ray diffraction. MATERIALS AND METHODS: A 12 mm × 12 mm SC sheet from hairless mouse was divided into 16 pieces measuring 3 mm × 3 mm square. From another sheet, 4 pieces of ultramillimeter-sized SC (USC:1.5 mm × 1.5 mm square) were prepared. Small and wide-angle X-ray diffraction (SAXD and WAXD) measurements were performed on each piece...
April 29, 2018: Skin Research and Technology
M Dąbrowska, A Mielcarek, I Nowak
BACKGROUND: Evaluation of skin condition on the basis of parametrization and objective measurements of the parameters has become obligatory. The aim of this study was to assess sex-related changes in skin topography and structure using the skin testing equipment. MATERIALS AND METHODS: The study was carried out on the group of 40 volunteers (20 females and 20 males) of the mean age 24 ± 3 years. The skin parameters were measured using 3 devices: Visioscan®  VC 98 (skin topography), Visioline® VL 650 (skin macro relief) and Ultrascan UC22 (ultrasound imaging of the skin)...
April 29, 2018: Skin Research and Technology
C Messaraa, A Metois, M Walsh, J Flynn, L Doyle, N Robertson, A Mansfield, C O'Connor, A Mavon
BACKGROUND: The cause of enlarged pores remains obscure but still remains of concern for women. To complement subjective methods, bioengineered methods are needed for quantification of pores visibility following treatments. The study objective was to demonstrate the suitability of pore measurements from the Antera 3D. MATERIAL AND METHODS: Pore measurements were collected on 22 female volunteers aged 18-65 years with the Antera 3D, the DermaTOP and image analysis on photographs...
April 29, 2018: Skin Research and Technology
M Morvová, P Jeczko, L Šikurová
BACKGROUND: Human skin naturally contains many endogenous fluorophores; therefore, fluorescence techniques can be used for monitoring of the human skin even in in vivo mode. The aim of this work was to study skin autofluorescence in vivo regarding the possible effect of gender. MATERIALS AND METHODS: Fluorescence emission spectra of young healthy Caucasian adults in 3 anatomical regions (forehead, hand, and inner upper arm) were taken with excitation at 280, 325, or 400 nm...
April 27, 2018: Skin Research and Technology
C Magalhaes, R Vardasca, J Mendes
BACKGROUND: Infrared thermal imaging captures the infrared radiation emitted by the skin surface. The thermograms contain valuable information, since the temperature distribution can be used to characterize physiological anomalies. Thus, the use of infrared thermal imaging (IRT) has been studied as a possible medical tool to aid in the diagnosis of skin oncological lesions. The aim of this review is to assess the current state of the applications of IRT in skin neoplasm identification and characterization...
March 25, 2018: Skin Research and Technology
S O'Leary, A Fotouhi, D Turk, P Sriranga, A Rajabi-Estarabadi, K Nouri, S Daveluy, D Mehregan, M Nasiriavanaki
BACKGROUND: Skin cancer represents the most prevalent type of cancer in the United States. Excision of these lesions can leave significant scarring, and a delay in the diagnosis of malignant melanoma could result in metastasis or death. Therefore, developing technology and criteria to accurately diagnose these cancers is of particular importance to the medical community. While biopsy can lead to scarring and infections, dermoscopy and confocal microscopy offer noninvasive imaging methods but are also limited in their ability to determine tumor depth and margins...
March 25, 2018: Skin Research and Technology
H Yoshida, A Komiya, R Ohtsuki, A Kusaka-Kikushima, S Sakai, K Kawabata, M Kobayashi, S Nakamura, A Nagaoka, T Sayo, Y Okada, Y Takahashi
BACKGROUND: Hyaluronan (HA) is an important constituent of extracellular matrix (ECM) in the skin, and HA degradation mediated by HYBID (KIAA1199) is suggested to be implicated in facial skin wrinkling in Japanese women. Ethnic difference in skin wrinkle formation is known between Caucasian and Japanese women, but no information is available for the relations of HA and HYBID expression levels with skin wrinkling in Caucasian women. METHODS: The skin surface roughness at the eye corner of the Caucasian female subjects was measured, and the skin specimens biopsied from the same areas were subjected to microarray gene analysis, HA staining, and immunohistochemistry for HYBID...
March 14, 2018: Skin Research and Technology
L Petit, D Zugaj, V Bettoli, B Dreno, S Kang, J Tan, V Torres, A M Layton, P Martel
BACKGROUND: One major sequelae of acne is atrophic scarring, yet objective tools to assess scars are lacking. Neither depth nor volume of atrophic scars is readily evaluable clinically and standard 2D photography is significantly affected by lighting and shadows. The aim of our study was to define and evaluate parameters of 3D imaging that can be used to assess severity of atrophic acne scarring. METHODS: Single center study of 31 patients with acne scarring. A target area of 3 × 3 cm was defined on the face...
March 6, 2018: Skin Research and Technology
J Y Choi, E J Kim, S I Jang, A R Kim, T J Lee, H K Lee
BACKGROUND: Dryness-related heel skin problems are common; however, there are very few studies about heel skin dryness. The objective of this study was to develop new assessment methods for evaluating heel skin dryness, to clarify the characteristics associated with heal skin dryness, and assess the effectiveness of moisturizer use according to dryness severity. MATERIALS AND METHODS: We investigated the heel skin of 150 Korean women (aged 20-78 years). Heel skin images were taken using a DSLR camera and the distribution or severity of flakes, scaling, cracking, and fissures were visually assessed...
March 1, 2018: Skin Research and Technology
A J B Andersen, C Fuchs, M Ardigo, M Haedersdal, M Mogensen
BACKGROUND AND OBJECTIVE: Malassezia Folliculitis (MaF) is an inflammatory condition of hair follicles caused by Malassezia yeast. Optical coherence tomography (OCT) and reflectance confocal microscopy (RCM) are imaging technologies enabling in vivo visualization of superficial skin layers. This study explores morphology of pustules in MaF imaged by OCT and RCM. METHODS: Patients with microscopically verified MaF were included in this case series. Morphology was evaluated qualitatively with RCM and OCT, focusing on shape, border and content of selected pustules...
February 27, 2018: Skin Research and Technology
G Boyer, N Lachmann, G Bellemère, C De Belilovsky, C Baudouin
BACKGROUND: A woman's skin is dramatically affected by pregnancy. Its biomechanical properties are critical for resisting highly stressed areas. The aim of this work was to evaluate the impact of pregnancy on the mechanical properties of skin, as well as to evaluate the imprint that pregnancy leaves on the skin after delivery. MATERIALS AND METHODS: Suction tests using a cutometer were performed on 15 non-pregnant women and 26 pregnant women at 8 months of pregnancy and 4 months after delivery...
February 26, 2018: Skin Research and Technology
D J du Preez, J L du Plessis, C Y Wright
BACKGROUND: Observing accurate real-time measurements of solar ultraviolet radiation (UVR) levels is important since personal excess sun exposure is associated with skin cancers. Handheld measurement devices may be helpful but their accuracy is unknown. We compare a portable, science-grade solar UVR monitoring device against two fixed, science-grade solar UVR instruments. METHODS: Instruments were (1) a fixed Solar Light 501 UV-B biometer to measure UV-B; (2) a fixed Kipp and Zonen radiometer used to measure UV-A and UV-B; and (3) Goldilux ultraviolet probes which are commercially available portable devices...
February 23, 2018: Skin Research and Technology
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