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Skin Research and Technology

Laura E Dellalana, Fuyao Chen, Arved Vain, Jocelyn S Gandelman, Mihkel Põldemaa, Heidi Chen, Eric R Tkaczyk
BACKGROUND: Clinical assessment of skin stiffness is unreliable in many applications. The durometer, an industrial device to measure hardness, has previously been applied in scleroderma. The Myoton is a noninvasive handheld device for assessing soft tissue biomechanical parameters. MATERIALS AND METHODS: We evaluated the reproducibility of both devices in six healthy subjects in the volar forearm, dorsal forearm, upper arm, shin, and calf bilaterally. The intraclass correlation coefficient (ICC) was used as a measure of reproducibility among three observers...
November 10, 2018: Skin Research and Technology
Aurélie Villaret, Célia Ipinazar, Tuvana Satar, Eléonore Gravier, Céline Mias, Emmanuel Questel, Anne-Marie Schmitt, Valérie Samouillan, Florence Nadal, Gwendal Josse
BACKGROUND: Skin aging is a complex biological process mixing intrinsic and extrinsic factors, such as sun exposure. At the molecular level, skin aging affects in particular the extracellular matrix proteins. MATERIALS AND METHODS: Using Raman imaging, which is a nondestructive approach appropriate for studying biological samples, we analyzed how aging modifies the matrix proteins of the papillary and reticular dermis. Biopsies from the buttock and dorsal forearm of volunteers younger than 30 and older than 60 were analyzed in order to identify chronological and photoaging processes...
November 7, 2018: Skin Research and Technology
Naoki Nishimura, Shinsuke Inoue, Keiko Yokoyama, Satoshi Iwase
BACKGROUND/PURPOSE: It is known that the elderly and adult women with reduction in sebum secretion have reduced skin barrier function, drying of the skin in a low humidity environment is accompanied by physiological distress. As our hypothesis, when fine water particles are sprayed on the skin, the water content of the corneal layer is significantly increased. In the present study, we examined the ability of fine water particles to improve facial skin moisture levels in adult women. METHODS: We examined skin conductance, transepidermal water loss (TEWL), and skin elasticity as an index of skin barrier function at the cheek in 17 healthy adult women in the spraying of fine water particles, in the environment temperature at 24°C and 34...
November 6, 2018: Skin Research and Technology
Gary Grove, Tim Houser, Gary Sibbald, Ginger Salvadalena
BACKGROUND: Ostomy barriers are adhesive devices designed to hold pouching systems to the abdomen and protect the peristomal skin from stoma effluent. The objective of this study was to determine differences in the extent of skin trauma resulting from serially applying and removing two types of ostomy barriers. METHODS: The study was a randomized, prospective, repeated measure trial involving healthy volunteers. The ostomy skin barriers were applied to the abdomen and changed every 3-4 days over a 17-day period...
November 2, 2018: Skin Research and Technology
Tomohisa Hirobe, Hisao Enami
INTRODUCTION: The classical study revealed the melanocyte density in the epidermis of many skin sites of humans. However, these data were obtained by counting melanocytes using dihydroxyphenylalanine (dopa)-treated epidermal sheets. Since rete ridges are developed well in human epidermis, there is a concern about the accuracy of these data. The accurate counting of the melanocyte density in the epidermis including the rete ridges should be performed using histological sections after the dopa treatment...
November 2, 2018: Skin Research and Technology
Miku Aoki, Kazuhiro Ogai, Masato Kobayashi, Takeo Minematsu, Toshio Nakatani, Mayumi Okuwa, Hiromi Sanada, Junko Sugama
BACKGROUND/PURPOSE: Skin care via moisturization compensates for the lack of skin barrier function. However, moisturizer application methods are not clearly decided. Here, we focused on and examined the retention of externally applied ceramide in the stratum corneum (SC) using fluorescent imaging method. This study aimed to compare ceramide retention in the SC between normal skin and dry skin using an animal model. METHODS: Nine-week-old Sprague-Dawley rats were divided into two groups: normal skin and dry skin model...
October 27, 2018: Skin Research and Technology
Elisa Cinotti, Marco Campoli, Giacomo Pataia, Youcef Ouerdane, Gilles Thuret, Philippe Gain, Linda Tognetti, Jean Luc Perrot, Pietro Rubegni
BACKGROUND: In the clinical practice, transparent films are used as sterile interfaces in in vivo dermatologic imaging in order to prevent the transmissions of infections. However, in our experience, the use of a transparent film can alter skin images. Our study aimed to compare the optical quality of a series of different plastic films used as interfaces in order to understand if some might be more suitable for imaging. MATERIALS AND METHODS: We tested the optical properties of 11 different protective transparent films that are marketed in France with a transparency meter and a spectrophotometer...
October 27, 2018: Skin Research and Technology
Alfageme Fernando, Nájera Laura, Fonda Pablo, Roustan Gastón
No abstract text is available yet for this article.
October 25, 2018: Skin Research and Technology
Hyerim Kim, Myeongryeol Lee, Sun Young Park, Yong Min Kim, Jiyeon Han, Eunjoo Kim
OBJECTIVE: Age-related changes in lip morphological and physiological characteristics are key indices for estimating age based on facial features, as reported in many studies. Yet, a majority of studies have focused on Caucasian individuals, with few studies characterizing these changes in Asian female populations. Therefore, the aim of this study was to investigate lip morphological and physiological characteristics in a cohort of Korean women. METHODS: A total of 114 volunteers participated in the study...
October 25, 2018: Skin Research and Technology
Francesco Lacarrubba, Anna Elisa Verzì, Rosario Caltabiano, Giuseppe Broggi, Angelo Di Natale, Giuseppe Micali
No abstract text is available yet for this article.
October 25, 2018: Skin Research and Technology
Yoo Sang Baek, Jaeyoung Kim, Jin Young Song, Jiehyun Jeon, Chil Hwan Oh
BACKGROUND: Diagnosis of actinic keratosis (AK) based only on clinical findings can be misleading, and histopathological diagnosis results in scars. Dynamic thermal imaging is a potential non-invasive tool for the diagnosis of AK. This imaging technique quantifies the infrared (IR) radiation emitted by a subject after exposure to external thermal stimuli, such as heat or cold. METHODS: Twenty-six histopathologically confirmed AK patients participated in the study...
October 25, 2018: Skin Research and Technology
Xiangzi Li, Yue Zheng, Congxiu Ye, Angelie Tengguna Theng, Diana, Songchao Yin, Wei Lai
BACKGROUND/AIMS: How to select a suitable method in whitening products evaluation is still under discussion. Here, we compared two different artificial pigmentation models and explored an ideal UV dosage for skin whitening products evaluation model establishment. METHODS: Thirty five healthy volunteers with type IV human skin were recruited and the skin minimal erythema dose (MEDs) and minimal persistent pigment dose (MPPDs) were measured. All volunteers were simultaneously exposed to six increasing doses of radiations from different ultraviolet sources on lower back bilateral flattening area: 95% UVA/5% UVB with the radiating doses of 0...
October 25, 2018: Skin Research and Technology
Christos Bontozoglou, Xu Zhang, Perry Xiao
BACKGROUND: In this study, the performance of capacitive imagining in skin micro-relief analysis was investigated. This measurement principle has been used for skin hydration measurements over the last decade and it is commercially available by various manufacturers. Strengthening its potential for new applications could offer an affordable and portable multi-purpose device for in vivo skin research. Previous studies in the literature have used a wide range of optical devices to determine how the skin surface topographic features are affected by chronological age, environmental influences and living habits...
October 22, 2018: Skin Research and Technology
Changhui Cho, Eunbyul Cho, Nahee Kim, Juhee Shin, Sanga Woo, Jiun Lee, Jungok Lee, Eunyoung Lee, Jaehyoun Ha
BACKGROUND: Striae distensae are common dermal lesions that progress through two different stages: the striae rubra, which appears to be erythematous, and striae alba, which is characterized by a hypopigmented feature. The clinical characteristics between striae distensae stages and normal skin remain unknown. OBJECTIVES: We aimed to investigate the clinical characteristics according to stages of striae distensae in terms of their biophysical properties, using objective noninvasive measurements in comparison with adjacent normal skin...
October 22, 2018: Skin Research and Technology
Sachie Kudo, Satoru Nakashima
BACKGROUND: Natures and amounts of water retained at the surface of stratum corneum (SC) of human skins, affecting skin health and penetration of chemical components, remain unclear. METHODS: A keratin film, a main component of human SC surface, was measured by IR micro-spectroscopy combined with a quartz crystal microbalance (QCM) and a relative humidity (RH) control system. RESULTS: Water contents increased with RH up to about 19 wt% and were correlated linearly with the OH + NH band areas in IR spectra of the keratin film...
October 22, 2018: Skin Research and Technology
Sai Yee Chuah, Steven Tien Guan Thng
No abstract text is available yet for this article.
October 22, 2018: Skin Research and Technology
Valerii Teplyi, Kateryna Grebchenko
BACKGROUND: The application of new techniques of the scars' correction requires the objective evaluation of their vascularization. OBJECTIVE: To evaluate the effectiveness of digital program ImageJ in assessing neovascularization of pathologic scars. MATERIAL AND METHODS: In this cross-sectional study, a total of 25 patients with pathologic scars were enrolled. Vessel selection in the first set of digital images of their scars was performed by computer processing started from thresholding with subsequent manual correction...
October 17, 2018: Skin Research and Technology
Linda Tognetti, Elisa Cinotti, Diletta Fiorani, Pietro Rubegni, Jean Luc Perrot
No abstract text is available yet for this article.
October 16, 2018: Skin Research and Technology
Heesu Kim, Keun Jae Ahn, Sugun Lee, Henry Park, Sung Bin Cho
BACKGROUND: Intense focused ultrasound (IFU) and radiofrequency (RF) systems generate thermal tissue reactions in multiple zones in the skin, with the microscopic features thereof varying according to energy sources and treatment parameters. OBJECTIVE: To evaluate interactive thermal tissue reactions of IFU and RF in cadaveric skin. METHODS: Thermal reaction patterns generated by IFU, invasive bipolar RF, and non-invasive monopolar RF treatments were analyzed in cadaveric skin of the inner thigh...
October 15, 2018: Skin Research and Technology
Anna Herman, Andrzej P Herman
This review presents the current state of knowledge regarding multifunctional role of human skin antimicrobial peptides (AMPs), including (a) protection from microbial infection, (b) improvement of skin barrier homoeostasis, (c) modulation of inflammation responses, and (d) promotion of wound healing. In addition, association of AMPs with skin diseases as well as challenges and future prospects for AMP therapeutics has also been discussed.
October 15, 2018: Skin Research and Technology
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