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Skin Research and Technology

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https://www.readbyqxmd.com/read/28517733/comparison-of-the-measuring-efficacy-of-transepidermal-water-loss-of-a-reasonably-priced-portable-closed-chamber-system-device-h4500-with-that-of-rather-expensive-conventional-devices-such-as-tewameter-%C3%A2-and-vapometer-%C3%A2
#1
K Kikuchi, M Asano, H Tagami, M Kato, S Aiba
BACKGROUND/PURPOSE: Although measuring transepidermal water loss (TEWL) is important to assess the barrier function of the stratum corneum (SC), the commercially available instruments are rather expensive. Recently launched Model H4500 employs a closed-chamber system to measure TEWL and is more reasonably priced compared to devices currently in general use. METHODS: To check the reproducibility of the obtained data with H4500, we conducted measurements on the volar forearms of healthy volunteers and compared these data with those measured with Vapometer(®) and Tewameter(®) ...
May 18, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28516727/non-invasive-longitudinal-monitoring-of-angiogenesis-in-a-murine-full-thickness-cutaneous-wound-healing-model-using-high-resolution-three-dimensional-ultrasound-imaging
#2
K Mukai, W Zhu, Y Nakajima, M Kobayashi, T Nakatani
BACKGROUND/PURPOSE: The aim of this study was to evaluate the longitudinal monitoring of angiogenesis in a murine full-thickness cutaneous wound healing model using high-resolution three-dimensional (3D) ultrasound imaging. METHODS: Two C57BL/6 mice were used. Two-dimensional (2D) ultrasound images with the Color Doppler mode were acquired at regular spatial intervals on day 9, 11, and 14 after wounding. 3D ultrasound images were processed by reconstructing the 2D ultrasound image sequences...
May 17, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28516572/identification-of-ageing-biomarkers-in-human-dermis-biopsies-by-thermal-analysis-dsc-combined-with-fourier-transform-infrared-spectroscopy-ftir-atr
#3
R Tang, V Samouillan, J Dandurand, C Lacabanne, M-H Lacoste-Ferre, P Bogdanowicz, P Bianchi, A Villaret, F Nadal-Wollbold
BACKGROUND/PURPOSE: The purpose of this clinical study was to identify suitable biomarkers for a better understanding of the molecular and organizational changes in human dermis during intrinsic and extrinsic ageing. METHODS: Sun-exposed and non-exposed skin biopsies were collected from twenty-eight women devised in two groups (20-30 and ≥60 years old). The hydric organization and thermal transitions were determined by Differential Scanning Calorimetry (DSC)...
May 17, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28514014/repeatability-of-vessel-density-measurement-in-human-skin-by-oct-based-microangiography
#4
S J Men, C-L Chen, W Wei, T-Y Lai, S Z Song, R K Wang
PURPOSE: To investigate the repeatability of vessel density measurement at human arm skin in healthy subjects with OCT-based microangiography (OMAG). METHODS: Four locations including volar wrist, volar forearm, shoulder, and volar upper arm were scanned using an optimized swept source OCT system, working at center wavelength of 1300 nm and A-line rate of 100 kHz. Three scans were acquired at each location at the same visit. Vascular images of papillary dermis, reticular dermis, and the whole dermis layer were generated with OMAG processing and automatic segmentation algorithms...
May 17, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28513064/autofluorescence-of-collagen-fibres-in-scar
#5
H L Zhao, C P Zhang, H Zhu, Y F Jiang, X B Fu
BACKGROUND/PURPOSE: Autofluorescence has become an important factor associated with diagnosis and treatment of many diseases. METHODS: Full thickness skin grafts and scar biopsies were obtained from five volunteers. The normal skin or scar tissue paraffin-wax sections were stained with HE and the autofluorescence of collagen fibres was viewed under fluorescence microscopy. RESULTS: In normal skin, the autofluorescence was showed in dermis, specifically in collagen fibres...
May 17, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28513053/high-frequency-ultrasound-quantification-of-acute-radiation-dermatitis-pilot-study-of-patients-undergoing-radiotherapy-for-breast-cancer
#6
M Garnier, E Champeaux, E Laurent, A Boehm, O Briard, T Wachter, L Vaillant, F Patat, G Bens, L Machet
BACKGROUND: Acute radiation dermatitis (ARD) is a frequent complication after breast cancer radiotherapy and is usually assessed by semi-quantitative clinical scores, which may be subject to inter-observer variability. High-frequency ultrasound imaging of the skin can reliably quantify thickness and edema in diseased skin. We aimed to compare the relative increase in dermal thickness of the irradiated zone in breast-cancer patients undergoing radiotherapy, with clinical severity. METHODS: A consecutive series of patients undergoing treatment for breast cancer by lumpectomy and radiotherapy in a 6-month period also underwent clinical and ultrasound evaluation of ARD...
May 17, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28513003/quantification-of-skin-erythema-response-to-topical-alcohol-in-alcohol-intolerant-east-asians
#7
Y Aoki, S L Wehage, P Talalay
BACKGROUND/PURPOSE: Severe alcohol intolerance characterized by flushing, headache, nausea, and tachycardia even after very modest oral alcohol consumption, is common among East Asians (Chinese, Japanese, Koreans) and has been associated with the accumulation of acetaldehyde resulting from genetic polymorphism of aldehyde dehydrogenase (ALDH). These individuals also display erythema of the skin in response to exposure to topical alcohol. We have recently observed that dietary phytochemicals such as sulforaphane can accelerate the disposal of acetaldehyde from cells and animals by inducing ALDH...
May 17, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28370745/in-vitro-methods-for-evaluating-skin-hydration-under-diapers-and-incontinence-products
#8
M L Tate, A S Wright
BACKGROUND/PURPOSE: Excessive skin hydration from wearing wet undergarments, such as infant diapers and adult incontinence products, has been historically problematic. Skin damage occurs from wetness (urine) and limited product breathability. Evaporative water loss has been measured on adult arms (armband method) or infant torsos (on-baby method), after wearing a saline-insulted diaper product. The current study developed a reliable in vitro method of evaluating diaper and incontinence products for improvements in skin dryness...
April 1, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28370413/intra-and-inter-individual-variability-in-the-mechanical-properties-of-the-human-skin-from-in-vivo-measurements-on-20-volunteers
#9
E Jacquet, J Chambert, J Pauchot, P Sandoz
BACKGROUND/PURPOSE: The mechanical properties and behavior of the human skin in vivo are of medical importance, particularly to surgeons who have to consider the skin extension capabilities in the preparation of surgical acts. Variable data can be found in literature that result from diverse kinds of tests (in vivo, ex vivo, and postmortem) performed with different instruments. METHODS: This paper presents the results of in vivo measurements performed on a cohort of 20 healthy volunteers with an ultralight homemade uniaxial extensometer...
March 30, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28349598/ultra-light-extensometer-for-the-assessment-of-the-mechanical-properties-of-the-human-skin-in-vivo
#10
E Jacquet, S Joly, J Chambert, K Rekik, P Sandoz
BACKGROUND/PURPOSE: This paper aims to present an ultra-light extensometer device dedicated to the mechanical characterization of the human skin in vivo. METHODS: The device developed was conceived to be non-invasive, to work without any stand and to perform various uniaxial tensile tests with either effort or displacement control. We also use specific guarding tabs to make in vivo extension tests analogous to traction tests. RESULTS: Force-displacement curves are derived from the data provided by the device's sensors...
March 28, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28326611/mechanical-characterization-of-curly-hair-influence-of-the-use-of-nonconventional-hair-straightening-treatments
#11
M G A Leite, P M B G Maia Campos
BACKGROUND/PURPOSE: Hair straighteners are very popular around the world, although they can cause great damage to the hair. Thus, the characterization of the mechanical properties of curly hair using advanced techniques is very important to clarify how hair straighteners act on hair fibers and to contribute to the development of effective products. On this basis, we chose two nonconventional hair straighteners (formaldehyde and glyoxylic acid) to investigate how hair straightening treatments affect the mechanical properties of curly hair...
March 21, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28317229/clinical-features-and-in-vivo-reflectance-confocal-microscopy-of-an-atypical-presentation-of-herpesvirus-2-and-cytomegalovirus-co-infection-of-the-intergluteal-sulcus
#12
LETTER
G Odorici, V D Mandel, A Giannetti, G Pellacani, A Conti
No abstract text is available yet for this article.
March 19, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28317176/periorbital-melasma-hierarchical-cluster-analysis-of-clinical-features-in-asian-patients
#13
Y S Jung, J M Bae, B J Kim, J-S Kang, S B Cho
BACKGROUND: Studies have shown melasma lesions to be distributed across the face in centrofacial, malar, and mandibular patterns. Meanwhile, however, melasma lesions of the periorbital area have yet to be thoroughly described. METHODS: We analyzed normal and ultraviolet light-exposed photographs of patients with melasma. The periorbital melasma lesions were measured according to anatomical reference points and a hierarchical cluster analysis was performed. RESULTS: The periorbital melasma lesions showed clinical features of fine and homogenous melasma pigmentation, involving both the upper and lower eyelids that extended to other anatomical sites with a darker and coarser appearance...
March 19, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28303612/infant-skin-maturation-preliminary-outcomes-for-color-and-biomechanical-properties
#14
M O Visscher, S A Burkes, D M Adams, A M Hammill, R R Wickett
BACKGROUND: Newborn infant skin changes after birth but studies have focused on the epidermal barrier. Dermal properties are relevant for care, but literature on postnatal changes is sparse. We further characterized skin maturational changes in lightness, color and response to biomechanical stress. METHODS: Normal skin sites from subsets of participants in a trial on the progression and stage of infantile hemangiomas were retrospectively examined. Standardized photographs were analyzed as L*, a*, and b* images...
March 16, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28303604/in-vivo-cleansing-efficacy-of-biodegradable-exfoliating-beads-assessed-by-skin-bioengineering-techniques
#15
J Kitsongsermthon, K Duangweang, J Kreepoke, A Tansirikongkol
BACKGROUND/PURPOSE: The plastic microbeads, used in many cleansers, will be banned in cosmetic and personal care products within 2017 since they are non-degradable and can disturb the living organisms in water reservoirs. Various choices of biodegradable beads are commercially available, but their efficacy has not been proven yet. This study aimed to compare the cleansing efficacy in dirt and sebum removal aspects of three types of exfoliating beads. METHODS: The gel scrubs with polyethylene (PE) beads, mannan beads or wax beads, were formulated and evaluated for their stability...
March 16, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28295641/wash-or-wipe-a-comparative-study-of-skin-physiological-changes-between-water-washing-and-wiping-after-skin-cleaning
#16
K Ogai, M Matsumoto, M Aoki, R Ota, K Hashimoto, R Wada, M Kobayashi, J Sugama
BACKGROUND/PURPOSE: Presently, skin-cleaning agents that claim to be removed by water or wiping alone are commercially available and have been used for the purpose of bed baths. However, there is a lack of knowledge on how water washing and wiping differently affect skin physiological functions or ceramide content. The aim of this study was to compare the effects of water washing and wiping on skin physiological functions and ceramide content. METHODS: Three kinds of the cleaning agents with different removal techniques (ie, water washing and wiping) were used in this study...
March 14, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28295631/relationship-between-the-changes-in-blood-flow-and-volume-in-the-finger-during-a-braille-character-discrimination-task
#17
J Murata, S Murata, M Soma, H Nakae, Y Sato, H Kogo, N Umeki
PURPOSE: We hypothesized that skin blood flow (SBF) of fingers are modulated during concentrated finger perception and that the changes in SBF reflect fluctuations in finger volume (FV). The aim of this study, therefore, was examine the relationship between the changes in SBF and FV during Braille reading. METHODS: We measured SBF of the finger, cutaneous vascular conductance (CVC), FV, and arterial blood pressure during Braille reading performed under blind conditions in thirty healthy subjects...
March 14, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28295674/skin-hydration-analysis-by-experiment-and-computer-simulations-and-its-implications-for-diapered-skin
#18
M Saadatmand, K J Stone, V N Vega, S Felter, S Ventura, G Kasting, J Jaworska
BACKGROUND: Experimental work on skin hydration is technologically challenging, and mostly limited to observations where environmental conditions are constant. In some cases, like diapered baby skin, such work is practically unfeasible, yet it is important to understand potential effects of diapering on skin condition. To overcome this challenge, in part, we developed a computer simulation model of reversible transient skin hydration effects. METHODS: Skin hydration model by Li et al...
March 13, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28295600/exogenous-and-endogenous-lipids-of-human-hair
#19
L Coderch, M A Oliver, V Martínez, A M Manich, L Rubio, M Martí
PURPOSE: The aim of this study was to characterize the external and internal lipids of Caucasian hair and their influence in different hair properties such as moisture content, hydrophobic character, and mechanical properties. METHODS: Lipid extraction and their analysis by thin layer chromatography with flame ionization detector were carried out. Lipid rearrangement and water sorption and desorption evaluation of these fibers with and without lipids will also be determined using different techniques such as differential scanning calorimetry, thermogravimetric analysis and dynamic vapor sorption, mainly to evaluate permeation changes of these hair fibers possibly related to the fluidity of the lipids extracted...
March 13, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28271554/examination-of-wound-healing-after-curettage-by-multiphoton-tomography-of-human-skin-in-vivo
#20
S Springer, M Zieger, A Böttcher, J Lademann, M Kaatz
BACKGROUND: The multiphoton tomography (MPT) has evolved into a useful tool for the non-invasive investigation of morphological and biophysical characteristics of human skin in vivo. Until now, changes of the skin have been evaluated mainly by using clinical and histological techniques. In this study, the progress of wound healing was investigated by MPT over 3 weeks with a final examination after 24 months. Especially, the collagen degradation, reepithelization and tissue formation were examined...
March 7, 2017: Skin Research and Technology
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