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Skin Research and Technology

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https://www.readbyqxmd.com/read/28585341/investigation-of-a-correlation-between-taxane-based-chemotherapy-and-the-ultrasonic-time-of-flight-of-human-fingernails
#1
R A Vacarescu, B Slak, A Maeva, C Hamm, N Lewoc, A T Daabous, E Strumban, R G Maev
BACKGROUND: Medical practitioners have long associated the physical appearance of human fingernails with certain underlying health conditions due to their direct connection to the vascular system. The objective of this study was to demonstrate how human fingernails can potentially be used as a biomarker to determine the severity of a patient's reaction to chemotherapy. METHODS: Quantitative investigation of fingernails in patients undergoing taxane-based chemotherapy was conducted using a high-frequency 50 MHz ultrasound device in B-mode in the form of a pilot study...
June 5, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28585335/comparison-of-two-skin-imaging-analysis-instruments-the-visia-%C3%A2-from-canfield-vs-the-antera-3d-%C3%A2-cs-from-miravex
#2
F Linming, H Wei, L Anqi, C Yuanyu, X Heng, P Sushmita, L Yiming, L Li
BACKGROUND: The skin imaging analysis instruments are widely used to record and measure the surface and subsurface skin conditions. The main aim of this study is to reveal the differences and correlations in measuring wrinkle, skin texture, coloration/evenness, vascular features, and pore between two commercially available instruments. METHODS: Twenty-eight subjects were enrolled in the study. A 2*2 cm cardboard was used to make sure the two instruments analyze the same area...
June 5, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28573767/measuring-contact-area-in-a-sliding-human-finger-pad-contact
#3
X Liu, M J Carré, Q Zhang, Z Lu, S J Matcher, R Lewis
BACKGROUND/PURPOSE: The work outlined in this paper was aimed at achieving further understanding of skin frictional behaviour by investigating the contact area between human finger-pads and flat surfaces. METHODS: Both the static and the dynamic contact areas (in macro- and micro-scales) were measured using various techniques, including ink printing, optical coherence tomography (OCT) and Digital Image Correlation (DIC). RESULTS: In the studies of the static measurements using ink printing, the experimental results showed that the apparent and the real contact area increased with load following a piecewise linear correlation function for a finger-pad in contact with paper sheets...
June 1, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28568473/facial-skin-photo-aging-and-development-of-hyperpigmented-spots-from-children-to-middle-aged-japanese-woman
#4
Y Takahashi, Y Fukushima, K Kondo, M Ichihashi
BACKGROUND/PURPOSE: Facial skin hyperpigmention caused by chronic sun exposure is a major skin complaint, however, its characteristics and influential factors are still limitedly known. METHODS: A cross-sectional survey in healthy Japanese women aged from 6 to 62 years (n=169) was conducted using a facial image analyzer VISIA(™) for knowing onset age of hyperpigmented spot formation, its chronological changes, and influence of environmental factors. RESULTS: UV Pigmented Spot (PS) Score was positively correlated with age (R=...
June 1, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28557064/quantitative-assessment-of-wound-healing-using-high-frequency-ultrasound-image-analysis
#5
H Mohafez, S A Ahmad, M Hadizadeh, S Moghimi, S A Roohi, M H Marhaban, M I Saripan, S Rampal
PURPOSE: We aimed to develop a method for quantitative assessment of wound healing in ulcerated diabetic feet. METHODS: High-frequency ultrasound (HFU) images of 30 wounds were acquired in a controlled environment on post-debridement days 7, 14, 21, and 28. Meaningful features portraying changes in structure and intensity of echoes during healing were extracted from the images, their relevance and discriminatory power being verified by analysis of variance. Relative analysis of tissue healing was conducted by developing a features-based healing function, optimised using the pattern-search method...
May 29, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28543874/ex-vivo-magnetic-resonance-imaging-using-hyaluronic-acid-fillers-differences-between-monophasic-and-biphasic-fillers
#6
M J Kim, W-J Moon, M S Hur, S H Han, Y W Lee, Y B Choe, K J Ahn
BACKGROUND/PURPOSE: Hyaluronic acid (HA) is an anionic, non-sulfated glycosaminoglycan distributed throughout the human skin and injectable HA fillers are the most commonly used in aesthetic field. This study aimed to determine if differences in physical characteristics of HA products (monophasic or biphasic fillers) affect the patterns of magnetic resonance imaging (MRI). METHODS: Twenty biphasic fillers and nine monophasic fillers were obtained from a commercial source, and examined with a 3...
May 25, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28543720/freeze-artifact-on-full-field-optical-coherence-tomography-skin-imaging
#7
J R Durkin, L Ogrich, D Morales-Neira, S Dundumalla, M Abdelmalek
BACKGROUND/PURPOSE: Full-field optical coherence tomography (FFOCT) is an emerging imaging technique for rapid histological analysis. As FFOCT is introduced into the Mohs workflow, it is important to document the effect of tissue freezing on FFOCT images and any effect FFOCT has on frozen sections. Our study aimed to evaluate the changes on FFOCT images after tissue freezing as well as FFOCT imaging effects on frozen sectioning. METHODS: Six normal skin specimens were imaged using FFOCT and subsequently frozen using a cryostat...
May 24, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28543622/in-vivo-exfoliating-efficacy-of-biodegradable-beads-and-the-correlation-with-user-s-satisfaction
#8
J Kitsongsermthon, J Kreepoke, K Duangweang, A Tansirikongkol
BACKGROUND/PURPOSE: By the end of 2017, non-biodegradable microbeads will be prohibited in USA, UK and Europe, due to their environmental issue. There are biodegradable beads available, but their effect on skin desquamation has not been evaluated yet. This study aimed to understand the skin renewal time, moisturizing effect and user's satisfaction of gel scrubs containing different exfoliating beads. METHODS: Gel scrubs, containing polyethylene, mannan or wax beads, were used in this study...
May 24, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28544155/oct-based-microangiography-for-reactive-hyperaemia-assessment-within-residual-limb-skin-of-people-with-lower-limb-loss
#9
LETTER
U Baran, E Swanson, J E Sanders, R K Wang
No abstract text is available yet for this article.
May 22, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28543777/efficacy-and-safety-of-non-invasive-body-tightening-with-high-intensity-focused-ultrasound-hifu
#10
E J Ko, J Y Hong, T-R Kwon, E J Choi, Y-J Jang, S Y Choi, K H Yoo, S Y Kim, B J Kim
BACKGROUND: Noninvasive skin-tightening devices have become increasingly popular in response to increasing demand for improvements in skin laxity and tightening with minimal risk and recovery time. OBJECTIVE: We evaluated the efficacy and safety of HIFU for skin tightening in the face and body. METHODS: A total of 32 Korean subjects enrolled in this prospective clinical trial. The subjects were treated with HIFU to both cheeks, lower abdomen, and thigh...
May 22, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28543966/development-of-a-quantitative-assessment-method-of-pigmentary-skin-disease-using-ultraviolet-optical-imaging
#11
Onseok Lee, Sunup Park, Jaeyoung Kim, Chilhwan Oh
BACKGROUND/PURPOSE: The visual scoring method has been used as a subjective evaluation of pigmentary skin disorders. Severity of pigmentary skin disease, especially melasma, is evaluated using a visual scoring method, the MASI (melasma area severity index). This study differentiates between epidermal and dermal pigmented disease. The study was undertaken to determine methods to quantitatively measure the severity of pigmentary skin disorders under ultraviolet illumination. METHODS: The optical imaging system consists of illumination (white LED, UV-A lamp) and image acquisition (DSLR camera, air cooling CMOS CCD camera)...
May 21, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28543606/reflectance-confocal-microscopy-analysis-of-equivocal-melanocytic-lesions-with-severe-regression
#12
M Agozzino, A Ferrari, C Cota, C Franceschini, P Buccini, L Eibenshutz, M Ardigò
BACKGROUND: The differential diagnosis between regressing nevi and melanoma might be challenging; regressing areas can represent a confounding factor for the diagnosis and the histology still remain mandatory to rule out melanoma. Reflectance confocal microscopy may add valuable information by revealing features suggestive of the nature of the melanocytic proliferation. OBJECTIVE: To assess the impact of confocal microscopy in the management of regressive melanocytic lesions...
May 21, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28517733/comparison-of-the-measuring-efficacy-of-transepidermal-water-loss-of-a-reasonably-priced-portable-closed-chamber-system-device-h4500-with-that-of-rather-expensive-conventional-devices-such-as-tewameter-%C3%A2-and-vapometer-%C3%A2
#13
K Kikuchi, M Asano, H Tagami, M Kato, S Aiba
BACKGROUND/PURPOSE: Although measuring transepidermal water loss (TEWL) is important to assess the barrier function of the stratum corneum (SC), the commercially available instruments are rather expensive. Recently launched Model H4500 employs a closed-chamber system to measure TEWL and is more reasonably priced compared to devices currently in general use. METHODS: To check the reproducibility of the obtained data with H4500, we conducted measurements on the volar forearms of healthy volunteers and compared these data with those measured with Vapometer(®) and Tewameter(®) ...
May 18, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28516727/non-invasive-longitudinal-monitoring-of-angiogenesis-in-a-murine-full-thickness-cutaneous-wound-healing-model-using-high-resolution-three-dimensional-ultrasound-imaging
#14
K Mukai, W Zhu, Y Nakajima, M Kobayashi, T Nakatani
BACKGROUND/PURPOSE: The aim of this study was to evaluate the longitudinal monitoring of angiogenesis in a murine full-thickness cutaneous wound healing model using high-resolution three-dimensional (3D) ultrasound imaging. METHODS: Two C57BL/6 mice were used. Two-dimensional (2D) ultrasound images with the Color Doppler mode were acquired at regular spatial intervals on day 9, 11, and 14 after wounding. 3D ultrasound images were processed by reconstructing the 2D ultrasound image sequences...
May 17, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28516572/identification-of-ageing-biomarkers-in-human-dermis-biopsies-by-thermal-analysis-dsc-combined-with-fourier-transform-infrared-spectroscopy-ftir-atr
#15
R Tang, V Samouillan, J Dandurand, C Lacabanne, M-H Lacoste-Ferre, P Bogdanowicz, P Bianchi, A Villaret, F Nadal-Wollbold
BACKGROUND/PURPOSE: The purpose of this clinical study was to identify suitable biomarkers for a better understanding of the molecular and organizational changes in human dermis during intrinsic and extrinsic ageing. METHODS: Sun-exposed and non-exposed skin biopsies were collected from twenty-eight women devised in two groups (20-30 and ≥60 years old). The hydric organization and thermal transitions were determined by Differential Scanning Calorimetry (DSC)...
May 17, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28514014/repeatability-of-vessel-density-measurement-in-human-skin-by-oct-based-microangiography
#16
S J Men, C-L Chen, W Wei, T-Y Lai, S Z Song, R K Wang
PURPOSE: To investigate the repeatability of vessel density measurement at human arm skin in healthy subjects with OCT-based microangiography (OMAG). METHODS: Four locations including volar wrist, volar forearm, shoulder, and volar upper arm were scanned using an optimized swept source OCT system, working at center wavelength of 1300 nm and A-line rate of 100 kHz. Three scans were acquired at each location at the same visit. Vascular images of papillary dermis, reticular dermis, and the whole dermis layer were generated with OMAG processing and automatic segmentation algorithms...
May 17, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28513064/autofluorescence-of-collagen-fibres-in-scar
#17
H L Zhao, C P Zhang, H Zhu, Y F Jiang, X B Fu
BACKGROUND/PURPOSE: Autofluorescence has become an important factor associated with diagnosis and treatment of many diseases. METHODS: Full thickness skin grafts and scar biopsies were obtained from five volunteers. The normal skin or scar tissue paraffin-wax sections were stained with HE and the autofluorescence of collagen fibres was viewed under fluorescence microscopy. RESULTS: In normal skin, the autofluorescence was showed in dermis, specifically in collagen fibres...
May 17, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28513053/high-frequency-ultrasound-quantification-of-acute-radiation-dermatitis-pilot-study-of-patients-undergoing-radiotherapy-for-breast-cancer
#18
M Garnier, E Champeaux, E Laurent, A Boehm, O Briard, T Wachter, L Vaillant, F Patat, G Bens, L Machet
BACKGROUND: Acute radiation dermatitis (ARD) is a frequent complication after breast cancer radiotherapy and is usually assessed by semi-quantitative clinical scores, which may be subject to inter-observer variability. High-frequency ultrasound imaging of the skin can reliably quantify thickness and edema in diseased skin. We aimed to compare the relative increase in dermal thickness of the irradiated zone in breast-cancer patients undergoing radiotherapy, with clinical severity. METHODS: A consecutive series of patients undergoing treatment for breast cancer by lumpectomy and radiotherapy in a 6-month period also underwent clinical and ultrasound evaluation of ARD...
May 17, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28513003/quantification-of-skin-erythema-response-to-topical-alcohol-in-alcohol-intolerant-east-asians
#19
Y Aoki, S L Wehage, P Talalay
BACKGROUND/PURPOSE: Severe alcohol intolerance characterized by flushing, headache, nausea, and tachycardia even after very modest oral alcohol consumption, is common among East Asians (Chinese, Japanese, Koreans) and has been associated with the accumulation of acetaldehyde resulting from genetic polymorphism of aldehyde dehydrogenase (ALDH). These individuals also display erythema of the skin in response to exposure to topical alcohol. We have recently observed that dietary phytochemicals such as sulforaphane can accelerate the disposal of acetaldehyde from cells and animals by inducing ALDH...
May 17, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28370745/in-vitro-methods-for-evaluating-skin-hydration-under-diapers-and-incontinence-products
#20
M L Tate, A S Wright
BACKGROUND/PURPOSE: Excessive skin hydration from wearing wet undergarments, such as infant diapers and adult incontinence products, has been historically problematic. Skin damage occurs from wetness (urine) and limited product breathability. Evaporative water loss has been measured on adult arms (armband method) or infant torsos (on-baby method), after wearing a saline-insulted diaper product. The current study developed a reliable in vitro method of evaluating diaper and incontinence products for improvements in skin dryness...
April 1, 2017: Skin Research and Technology
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