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Journal of Spinal Cord Medicine

Akira Ikumi, Shigeki Kubota, Yukiyo Shimizu, Hideki Kadone, Aiki Marushima, Tomoyuki Ueno, Hiroaki Kawamoto, Yasushi Hada, Akira Matsumura, Yoshiyuki Sankai, Masashi Yamazaki
CONTEXT: Recently, locomotor training with robotic assistance has been found effective in treating spinal cord injury (SCI). Our case report examined locomotor training using the robotic suit hybrid assistive limb (HAL) in a patient with complete C4 quadriplegia due to chronic SCI. This is the first report examining HAL in complete C4 quadriplegia. FINDINGS: The patient was a 19-year-old man who dislocated C3/4 during judo 4 years previously. Following the injury, he underwent C3/4 posterior spinal fusion but remained paralyzed despite rehabilitation...
October 20, 2016: Journal of Spinal Cord Medicine
Özlem Taşoğlu, Engin Koyuncu, Rabia Daylak, Derya Yumuşak Karacif, Zerrin I Nce, Didem Yenigün, Neşe Özgirgin
OBJECTIVE: To define the demographic and clinical characteristics of persons with spinal cord injury, rehabilitated in a primary referral rehabilitation center in Turkey. DESIGN: Retrospective study. SETTING: Ankara Physical Medicine and Rehabilitation Training and Research Hospital, Ankara, Turkey Methods: Medical records of all patients with spinal cord injury (acute-subacute-chronic) at a single academic referral center over the course of one year were reviewed...
October 20, 2016: Journal of Spinal Cord Medicine
Saul Wilson, Kingsley O Abode-Iyamah, John W Miller, Chandan G Reddy, Sina Safayi, Douglas C Fredericks, Nicholas D Jeffery, Nicole A DeVries-Watson, Sara K Shivapour, Stephanus Viljoen, Brian D Dalm, Katherine N Gibson-Corley, Michael D Johnson, George T Gillies, Matthew A Howard
OBJECTIVE: To develop a large animal model of spinal cord injury (SCI), for use in translational studies of spinal cord stimulation (SCS) in the treatment of spasticity. We seek to establish thresholds for the SCS parameters associated with reduction of post-SCI spasticity in the pelvic limbs, with implications for patients. STUDY DESIGN: The weight-drop method was used to create a moderate SCI in adult sheep, leading to mild spasticity in the pelvic limbs. Electrodes for electromyography (EMG) and an epidural spinal cord stimulator were then implanted...
October 19, 2016: Journal of Spinal Cord Medicine
Kanan Yatsuya, Satoshi Hirano, Eiichi Saitoh, Shigeo Tanabe, Hirotaka Tanaka, Masayuki Eguchi, Masaki Katoh, Yasuhiro Shimizu, Akito Uno, Hitoshi Kagaya
OBJECTIVE: To compare the energy efficiency of Wearable Power-Assist Locomotor (WPAL) with conventional knee-ankle-foot orthoses (MSH-KAFO) such as Hip and Ankle Linked Orthosis (HALO) or Primewalk. STUDY DESIGN: Cross over case-series. SETTING: Chubu Rosai Hospital, Aichi, Japan, which is affiliated with the Japan Organization of Occupational Health and Safety. METHODS: Six patients were trained with MSH-KAFO (either HALO or Primewalk) and WPAL...
October 17, 2016: Journal of Spinal Cord Medicine
Ashraf S Gorgey, Zachary A Graham, William A Bauman, Christopher Cardozo, David R Gater
STUDY DESIGN: Longitudinal design. OBJECTIVES: The study determined the effects of two forms of exercise training on the abundance of two proteins, (glucose transporter-4 [GLUT-4], adenosine monophosphate kinase [AMPK]) involved in glucose utilization and the transcriptional coactivator that regulates the genes involved in energy metabolism and mitochondrial biogenesis (peroxisome proliferator-activated receptor (PPAR) coactivator 1 alpha [PGC-1α]), in muscles in men with chronic motor-complete spinal cord injury (SCI)...
October 13, 2016: Journal of Spinal Cord Medicine
Engin Koyuncu, Güldal Funda Nakipoğlu Yüzer, Didem Yenigün, Neşe Özgirgin
STUDY DESIGN: Retrospective study. OBJECTIVES: The purposes of this investigation were to evaluate the serum lipid profile among a broad sample of patients with spinal cord injury (SCI), examining the impact of disease duration, lesion level, lesion grade and functional activity level on serum lipid levels of patients with SCI. SETTING: Ankara Physical Medicine and Rehabilitation Training and Research Hospital, Turkey. METHODS: Serum lipid profiles of 269 participants with SCI were analyzed and correlated to disease duration, lesion level, lesion grade and ambulation status...
October 13, 2016: Journal of Spinal Cord Medicine
Daniele Starnoni, John Michael Duff, Gopalakrishnan Chittur Viswanathan
CONTEXT: Anatomical variations of the filum terminale (FT) have been described in association with split cord malformations (SCM) but they appear to be a rare finding in its absence. We report the first case in literature of a duplicated FT in a patient presenting with tethered cord syndrome (TCS) without any radiological evidence of SCM. FINDINGS: A 47-year-old man presented with invalidating back pain radiating to both legs. Magnetic resonance imaging revealed an intradural dorsal lipoma in a low-lying conus...
October 13, 2016: Journal of Spinal Cord Medicine
Yingli Jing, Fan Bai, Hui Chen, Hao Dong
BACKGROUND: Melatonin can be neuroprotective in models of neurological injury, but its effects on blood vessel loss and neurological impairment following spinal cord injury (SCI) are unclear. Our goal herein was to evaluate the possible protective action of melatonin on the above SCI-induced damage in rats. MATERIALS AND METHODS: Sixty-three female Sprague-Dawley rats were randomly divided into three equal groups: sham, SCI and melatonin groups. Melatonin (10 mg/kg) was injected intraperitoneally and further administered twice a day at indicated time after a moderate injury at T10 in melatonin group...
October 13, 2016: Journal of Spinal Cord Medicine
Krista L Best, Karen Ethans, B Catharine Craven, Luc Noreau, Sander L Hitzig
OBJECTIVE: To identify and classify quality of life (QoL) tools for assessing the influence of neurogenic bladder after spinal cord injury/disease (SCI). DESIGN: Systematic Review Methods: Medline/Pubmed, CINAHL, and PsycInfo were searched using terms related to SCI, neurogenic bladder and QoL. Studies that assessed the influence neurogenic bladder on QoL (or related construct) in samples consisting of ≥50% individuals with SCI were included. Two independent reviewers screened titles and abstracts of 368 identified references; 118 full-text articles were assessed for eligibility, and 42 studies were included...
October 13, 2016: Journal of Spinal Cord Medicine
Hussein Algahtani, Bader Shirah, Raafat Ahmad, Hind Abobaker, Mohammed Hmoud
CONTEXT: Methanol is the simplest member of alcohol family. However, it is an extremely toxic substance to humans upon exposure with severe and detrimental effects that range from visual loss to death. Spinal cord involvement in methanol intoxication is a rare occurrence. FINDINGS: In this article, we are reporting a case of methanol intoxication with extensive spinal cord involvement possibly due to necrosis. A literature review yielded only two cases of spinal cord involvement due to methanol intoxication...
October 6, 2016: Journal of Spinal Cord Medicine
Lizette Norin, Björn Slaug, Maria Haak, Sophie Jörgensen, Jan Lexell, Susanne Iwarsson
OBJECTIVES: To describe the housing situation and aspects of participation among older adults living with long-standing spinal cord injury (SCI) with attention to SCI severity, and to examine whether and how objective housing accessibility (based on objectively measurable criteria) is associated with aspects of participation. DESIGN: Cross-sectional study utilizing the assessment tools Impact on Participation and Autonomy (IPA) and Housing Enabler (HE). Adjusting for demographic, social and injury related data, associations between objective housing accessibility and aspects of participation were analyzed by means of ordinal regression models...
September 16, 2016: Journal of Spinal Cord Medicine
Rory A Cooper
Assistive technology is essential to people with spinal cord injuries (SCI) for living and participating in their communities. However, many people with SCI do not have access to adequate assistive technology and qualified services. The World Health Organization (WHO) is addressing this need through the Global Cooperation on Assistive Technology (GATE). The GATE initiative is focused on improving access to high-quality affordable AT world-wide. GATE working to meet the AT sector needs in response to the call by WHO to increase access to essential, high-quality, safe, effective and affordable medical devices, which is one of the six WHO leadership priorities...
September 16, 2016: Journal of Spinal Cord Medicine
Noureddin Nakhostin Ansari, Mina Kashi, Soofia Naghdi
OBJECTIVE: To adapt the Spinal Cord Injury Spasticity Evaluation Tool (SCI-SET) into the Persian language (SCI-SETp) and to examine the reliability and validity of the SCI-SETp in patients with spinal cord injury (SCI). DESIGN: A cross-sectional and prospective cohort validation study. SETTING: University Neurological Physiotherapy Clinic. PARTICIPANTS: Adult patients with SCI. MAIN OUTCOME MEASURES: SCI-SET...
August 31, 2016: Journal of Spinal Cord Medicine
Young In Eom, Min Kim, In Soo Joo
OBJECTIVES: The aim of this study was to assess the characteristics of neuropathic pain after non-traumatic, non-compressive (NTNC) myelopathy and find potential predictors for neuropathic pain. DESIGN: We analyzed 54 patients with NTNC myelopathy. The Short Form McGill Pain Questionnaire (SF-MPQ) and the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) were used to assess pain. Health-related QOL was evaluated by the Short Form 36-item (SF-36) health survey...
August 31, 2016: Journal of Spinal Cord Medicine
Yasin Abanoz, Yeşim Abanoz, Ayşegül Gündüz, Murat Uludağ, Nurettin I˙rem Örnek, Nurten Uzun, Halil Ünalan, Meral Kızıltan
INTRODUCTION: Spinal cord injury (SCI) may cause functional changes at various levels in central and peripheral nervous systems. One of these changes is increased excitability above the lesion such as enhanced auditory startle responses (ASR). Startle response may also be obtained after somatosensory stimulus (startle reflex to somatosensory stimuli, SSS). In this study, we investigated changes of both ASR and SSS in SCI. METHOD: We examined ASR and SSS in 14 patients with SCI and 18 age-matched healthy volunteers...
August 31, 2016: Journal of Spinal Cord Medicine
Sareh Pandamooz, Mohammad Saied Salehi, Mohammad Nabiuni, Leila Dargahi
OBJECTIVE: Spinal cord injury (SCI) is a devastating condition causing neuronal loss. A key challenge in treatment of SCI is how to retain neurons after injury. Valproic acid (VPA) is a drug recently has been appreciated for its neuroprotective and neurotrophic properties in various SCI models. In this study the role of VPA was assessed in organotypic spinal cord slice culture following the contusion. DESIGN: The lumbar enlargement of adult rat was cut transversely and slices were cultured...
August 31, 2016: Journal of Spinal Cord Medicine
So Eyun Park, Stacy Elliott, Vanessa K Noonan, Nancy P Thorogood, Nader Fallah, Allan Aludino, Marcel F Dvorak
OBJECTIVE: The disruption of autonomic function following a spinal cord injury (SCI) is common and can negatively affect quality of life. The objective of this study was to describe the prevalence of bladder/bowel incontinence and sexual dysfunction in community-dwelling individuals with a thoracolumbar SCI and examine the impact on general physical and mental health status. METHODS: Participants who sustained a traumatic SCI to the thoracolumbar region of the spinal cord and classified as American Spinal Injury Association Impairment Scale (AIS) A to D were recruited...
August 31, 2016: Journal of Spinal Cord Medicine
Hadis Sabour, Abbas Norouzi Javidan, Zahra Soltani, Amir H Pakpour, Mir Saeed Yekaninejad, Seyedeh A Mousavifar
OBJECTIVE: The efficacy of nutrition education on body weight and serum lipids has not yet been described in patients with spinal cord injury (SCI). In the present study, we examined the effect of a 7-month nutrition education program on lipid profile and body weight in individuals with SCI. DESIGN: Randomized clinical trial. SETTING: A tertiary rehabilitation center. PARTICIPANTS: Patients with SCI who were referred to Brain and Spinal Cord Injury Research Center...
August 25, 2016: Journal of Spinal Cord Medicine
Joceline S Liu, Caroline Dong, Amanda X Vo, Laura Jo Dickmeyer, Claudia L Leung, Richard A Huang, Stephanie J Kielb, Shubhra Mukherjee
OBJECTIVE: Diagnosis of obesity using traditional body mass index (BMI) using length may not be a reliable indicator of body composition in spina bifida (SB). We examine traditional and surrogate measures of adiposity in adults with SB, correlated with activity, metabolic disease, attitudes towards exercise and quality of life. DESIGN: Adult subjects with SB underwent obesity classification using BMI by length and arm span, abdominal girth and percent trunk fat (TF) on dual energy X-ray absorptiometry (DXA)...
August 23, 2016: Journal of Spinal Cord Medicine
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September 2016: Journal of Spinal Cord Medicine
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