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Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]

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https://www.readbyqxmd.com/read/28614091/injectable-daxibotulinumtoxina-for-the-treatment-of-glabellar-lines-a-phase-2-randomized-dose-ranging-double-blind-multicenter-comparison-with-onabotulinumtoxina-and-placebo
#1
Jean Carruthers, Nowell Solish, Shannon Humphrey, Nathan Rosen, Channy Muhn, Vince Bertucci, Arthur Swift, Andrei Metelitsa, Roman G Rubio, Jacob Waugh, John Quiring, Gill Shears, Alastair Carruthers
BACKGROUND: Injectable daxibotulinumtoxinA (RT002) is an investigational botulinum toxin Type A in clinical development. It is formulated with a proprietary peptide and offers the potential of a longer acting neurotoxin therapy. OBJECTIVE: To compare the safety, efficacy, and duration of response of daxibotulinumtoxinA with onabotulinumtoxinA and placebo [www.clinicaltrials.gov NCT02303002]. METHODS: In this Phase 2, randomized, dose-ranging, parallel-group, double-blind, multicenter study, subjects with moderate or severe glabellar lines at maximum frown were randomly assigned to 20U, 40U, or 60U daxibotulinumtoxinA, 20U onabotulinumtoxinA, or placebo...
June 12, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28614090/three-dimensional-topography-of-the-supratrochlear-nerve-with-reference-to-the-lacrimal-caruncle-and-its-danger-zone-in-asians
#2
Young-Chun Gil, Shin-Hyo Lee, Kang-Jae Shin, Wu-Chul Song, Ki-Seok Koh, Hyun Jin Shin
BACKGROUND: The supratrochlear nerve (STN) is relatively superficial and therefore vulnerable to iatrogenic injury. OBJECTIVE: To elucidate the course of STN with reference to the lacrimal caruncle, with the aim of preventing nerve injury during surgery in the forehead region. MATERIALS AND METHODS: Thirty-four hemifaces from 18 Korean cadavers were dissected. The vertical line through the apex of lacrimal caruncle and the horizontal line through the supraorbital margin were used as horizontal and vertical reference lines, respectively...
June 12, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28595252/recurrent-tumors-referred-for-mohs-micrographic-surgery-a-12-year-experience-at-a-single-academic-center
#3
H William Higgins, Sara Capobianco, Kachiu C Lee
BACKGROUND: Mohs micrographic surgery (MMS) is used for treatment of primary and recurrent tumors. Compared with primary tumors, recurrent tumors are often more aggressive. OBJECTIVE: To understand differing characteristics between primary versus recurrent tumors treated by MMS. MATERIALS AND METHODS: The authors conducted a retrospective review of a 12-year period at 1 academic center. Recurrent tumors were defined as recurrent if previously treated with cryotherapy, topical chemotherapeutics, electrodesiccation and curettage, or excision...
June 6, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28595251/use-of-turn-in-skin-flaps-for-nasal-lining-reconstruction
#4
Memet Yazar, Sevgi Kurt Yazar, Erol Kozanoğlu, Murat Diyarbakırlıoğlu, Hikmet İhsan Eren
BACKGROUND: Reconstruction of the nasal lining is the most difficult part of complex nasal reconstruction because the mucosa has a unique texture and fineness. Many techniques, ranging from skin grafts to local flaps, have been applied for the reconstruction of the mucosa. In some cases, even free flaps have been used. OBJECTIVE: The aim of this study was to discuss the feasibility of using turn-in flaps in nasal reconstruction. MATERIALS AND METHODS: Seventeen patients with full-thickness nasal defects underwent reconstruction with turn-in flaps...
June 6, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28595250/prospective-split-face-randomized-long-term-blinded-objective-comparison-of-the-performance-and-tolerability-of-two-new-hyaluronic-acid-fillers
#5
Patrick Trevidic, Pierre Andre, Laurent Benadiba, Jean-Jacques Deutsch, Olivier Galatoire, Philippe Garcia, Anne Grand-Vincent, Sylvie Boisnic, Jean-Charles Kerihuel, Catherine Salomon
BACKGROUND: There are requirements for long-term, objective comparisons of hyaluronic acid (HA) dermal fillers. OBJECTIVE: To compare efficacy and tolerability of ART FILLER Universal (AFU) and ART FILLER Fine lines (AFFL) with the existing HA fillers for the treatment of nasolabial folds and crow's feet. MATERIALS AND METHODS: Prospective, randomized, rater- and patient-blind, split-face comparison of AFU with JUVEDERM Ultra 3 (JUV) and AFFL with FIRST LINES PureSense (FLPS)...
June 6, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28595249/a-prospective-randomized-single-blind-study-comparing-cyanoacrylate-adhesives-to-sutures-for-wound-closure-in-skin-cancer-patients
#6
Diana W Bartenstein, Deborah L Cummins, Gary S Rogers
BACKGROUND: Cyanoacrylate tissue adhesives are not more likely to result in wound dehiscence or infection than sutured closures. However, suturing is the gold standard for optimal cosmetic appearance of scars. OBJECTIVE: To determine whether cyanoacrylate tissue adhesives produce a cosmetic outcome equivalent to sutures at 3 months. Secondary outcomes include time for wound closure, time spent on wound care, and surgeon and patient satisfaction. METHODS AND MATERIALS: Seventy-one patients scheduled for skin cancer excision at Beverly Hospital were included in this prospective, randomized, single-blind study...
June 6, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28595248/novel-camera-mounting-technique-for-dermatologic-surgeries
#7
Baran Ho, Ali M Rkein, Heidi B Donnelly
No abstract text is available yet for this article.
June 6, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28595247/mohs-melanoma-chemosurgery-simplified-to-a-single-brief-caustic-application-possible-vaccine-effect
#8
Norman A Brooks
No abstract text is available yet for this article.
June 6, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28595246/cryolipolysis-for-reduction-of-arm-fat-safety-and-efficacy-of-a-prototype-coolcup-applicator-with-flat-contour
#9
Jean D Carruthers, Shannon Humphrey, Jason K Rivers
BACKGROUND: Cryolipolysis of the arms has been shown to be an effective but somewhat time-consuming process. OBJECTIVE: The study evaluated safety and efficacy of a contoured cup cryolipolysis applicator for reduction of arm fat. The prototype was designed to maximize tissue contact with the cooling surface to improve comfort, while reducing treatment time by 25 minutes. METHODS AND MATERIALS: Both arms were treated using a prototype device that delivered treatment in 35 minutes at -11°C...
June 6, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28595245/massively-metastatic-dermatofibrosarcoma-protuberans-with-fibrosarcomatous-transformation-years-after-surgical-resection
#10
Teo Soleymani, Catherine Ni, Anna Laury, Jashin J Wu
No abstract text is available yet for this article.
June 6, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28595244/dermoscopy-in-facilitating-the-recognition-of-poikiloderma-of-civatte
#11
Enzo Errichetti, Giuseppe Stinco
No abstract text is available yet for this article.
June 6, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28595243/determinants-and-timeline-of-perioperative-anxiety-in-mohs-surgery
#12
Irèn Kossintseva, David Zloty
BACKGROUND: Patients undergoing Mohs micrographic surgery (MMS) exhibit anxiety relating to cancer cure or the expected cosmetic outcome. OBJECTIVE: To obtain quantitative measurements of perioperative cancer and cosmetic anxiety levels in first-time MMS patients. Parameters influencing anxiety and its natural course were assessed. METHODS: Prospective, single-blinded, questionnaire study of 173 patients undergoing MMS of the face. Anxiety levels were assessed using a visual analog scale preoperatively and postoperatively over 6 months...
June 6, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28595242/three-dimensional-imaging-as-a-novel-method-of-evaluating-the-longevity-of-hyaluronic-acid-fillers-in-a-mouse-model
#13
Sun Young Choi, Eun Ja Choi, Joon Hyuk Suh, Beom Joon Kim, Sun Young Choi
No abstract text is available yet for this article.
June 6, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28562439/impact-of-smoke-evacuation-on-patient-experience-during-mohs-surgery
#14
Yousif Yonan, Shari Ochoa
BACKGROUND: There have been several investigations into possible health risks of surgical smoke exposure, and it has previously been associated with harboring pathogens and carcinogens. Patients in the authors' practice have expressed that the odor from the smoke created by electrosurgical equipment is unpleasant. OBJECTIVE: The authors sought to determine if smoke evacuation decreases patient perception of smoke created by electrosurgery during Mohs surgery and if it subsequently improves patient satisfaction with their surgical experience by minimizing the associated odor...
May 25, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28562438/retrospective-evaluation-of-topical-bimatoprost-and-iris-pigmentation-change
#15
Lisa A Zaleski-Larsen, Nadine H Ruth, Sabrina G Fabi
BACKGROUND: Topical bimatoprost is a topical prostaglandin analog originally used to treat glaucoma and more recently used to cosmetically induce hypertrichosis of the eyelashes. Iris pigmentation change has been noted in the treatment of glaucoma but has not been assessed with the cosmetic periorbital application of bimatoprost. OBJECTIVE: To evaluate for iris pigmentation change with the long-term cosmetic use of topical bimatoprost. MATERIALS AND METHODS: A retrospective chart review in a cosmetic dermatology practice of women (N = 50) who consistently purchased topical bimatoprost over an average of 4...
May 25, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28562437/use-of-skin-biopsies-among-dermatologists
#16
David A Weinstein, Sasank Konda, Brett M Coldiron
BACKGROUND: Skin biopsies are essential to establish a diagnosis in many skin diseases. Utilization has been increasing rapidly and represents a significant health care cost. There are no benchmarks or baselines to guide the practice of skin biopsies. OBJECTIVE: To create a reference data set of biopsy behavior among dermatologists. METHODS: Five hundred eighty-eight dermatologists belonging to the American Dermatological Association (ADA) were surveyed...
May 25, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28562436/comment-on-double-blind-placebo-controlled-pilot-study-on-the-use-of-platelet-rich-plasma-in-women-with-female-androgenetic-alopecia
#17
Rubina Alves, Ramon Grimalt
No abstract text is available yet for this article.
May 25, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28562435/calcium-hydroxylapatite-dermal-filler-for-treatment-of-dorsal-hand-volume-loss-results-from-a-12-month-multicenter-randomized-blinded-trial
#18
Mitchel P Goldman, Amir Moradi, Michael H Gold, Daniel P Friedmann, Kaveh Alizadeh, Jeffrey M Adelglass, Bruce E Katz
BACKGROUND: Calcium hydroxylapatite (CaHA) microspheres suspended in a carrier gel is an opaque dermal filler that has been used to provide immediate volume correction in the dorsal hands. OBJECTIVE: To assess the safety and effectiveness of CaHA for the correction of volume loss in the hands up to 12 months. MATERIALS AND METHODS: This multicenter, controlled, single-blind study (NCT01832090) included 114 subjects randomized 3:1 to CaHA treatment and untreated control groups...
May 25, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28562434/treatment-of-actinic-keratoses-a-randomized-split-site-approach-comparison-of-sequential-5-fluorouracil-and-5-aminolevulinic-acid-photodynamic-therapy-to-5-aminolevulinic-acid-photodynamic-monotherapy
#19
Susan Pei, Edidiong C N Kaminska, Maria M Tsoukas
BACKGROUND: Actinic keratoses (AKs) are skin lesions resulting from sun exposure and carry a risk of developing into squamous cell carcinoma. Current therapies for AK eradication include topical 5-fluorouracil (5-FU) and photodynamic therapy (PDT) with topical 5-aminolevulinic acid (ALA). However, sequential therapy with 5-FU-ALA-PDT may offer improved outcome compared to ALA-PDT alone. OBJECTIVE: The purpose of this study is to compare the long-term efficacy of AK clearance by sequential therapy with 5-FU-ALA-PDT versus ALA-PDT alone...
May 25, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28562433/platelet-rich-plasma-in-combination-with-5-minoxidil-topical-solution-and-1-mg-oral-finasteride-for-the-treatment-of-androgenetic-alopecia-a-randomized-placebo-controlled-double-blind-half-head-study
#20
Rubina Alves, Ramon Grimalt
No abstract text is available yet for this article.
May 25, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
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