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Journal of the International Neuropsychological Society: JINS

Vanessa Siffredi, Vicki Anderson, Alissandra McIlroy, Amanda G Wood, Richard J Leventer, Megan M Spencer-Smith
OBJECTIVES: Agenesis of the corpus callosum (AgCC), characterized by developmental absence of the corpus callosum, is one of the most common congenital brain malformations. To date, there are limited data on the neuropsychological consequences of AgCC and factors that modulate different outcomes, especially in children. This study aimed to describe general intellectual, academic, executive, social and behavioral functioning in a cohort of school-aged children presenting for clinical services to a hospital and diagnosed with AgCC...
March 7, 2018: Journal of the International Neuropsychological Society: JINS
Leigh E Colvin, Matteo Malgaroli, Silvia Chapman, Anna MacKay-Brandt, Stephanie Cosentino
OBJECTIVES: Emerging work reveals the neuroanatomic changes that compromise metacognition; however, little is known about the impact of premorbid factors. Research suggests that psychological variables influence the perception of cognition, but whether they influence the accuracy of those perceptions (i.e., metacognition) has not been directly examined. PARTICIPANTS AND METHODS: Using Latent Class Analysis (LCA), we tested for discrete personality (NEOFFI) and mood (STAI, BDI-II, and GDS) classes among a community-based cohort of 151 older adults, enrolled in the NKI-Rockland study...
February 5, 2018: Journal of the International Neuropsychological Society: JINS
Laura J Grande, Meghan E Robinson, Lauren J Radigan, Laura K Levin, Catherine B Fortier, William P Milberg, Regina E McGlinchey
OBJECTIVES: This study investigated the relationship between close proximity to detonated blast munitions and cognitive functioning in OEF/OIF/OND Veterans. METHODS: A total of 333 participants completed a comprehensive evaluation that included assessment of neuropsychological functions, psychiatric diagnoses and history of military and non-military brain injury. Participants were assigned to a Close-Range Blast Exposure (CBE) or Non-Close-Range Blast Exposure (nonCBE) group based on whether they had reported being exposed to at least one blast within 10 meters...
January 24, 2018: Journal of the International Neuropsychological Society: JINS
Shayden D Bryce, Susan L Rossell, Stuart J Lee, Richard J Lawrence, Eric J Tan, Sean P Carruthers, Jennie L Ponsford
OBJECTIVES: The aim of this study was to evaluate the impact of computer-assisted "drill-and-strategy" cognitive remediation (CR) for community-dwelling individuals with schizophrenia on cognition, everyday self-efficacy, and independent living skills. METHODS: Fifty-six people with schizophrenia or schizoaffective disorder were randomized into CR or computer game (CG) playing (control), and offered twenty 1-hr individual sessions in a group setting over 10 weeks...
January 21, 2018: Journal of the International Neuropsychological Society: JINS
Andrea R Zammit, Charles B Hall, Richard B Lipton, Mindy J Katz, Graciela Muniz-Terrera
OBJECTIVES: The aim of this study was to identify natural subgroups of older adults based on cognitive performance, and to establish each subgroup's characteristics based on demographic factors, physical function, psychosocial well-being, and comorbidity. METHODS: We applied latent class (LC) modeling to identify subgroups in baseline assessments of 1345 Einstein Aging Study (EAS) participants free of dementia. The EAS is a community-dwelling cohort study of 70+ year-old adults living in the Bronx, NY...
January 10, 2018: Journal of the International Neuropsychological Society: JINS
Benjamin L Brett, Andrew W Kuhn, Aaron M Yengo-Kahn, Aaron S Jeckell, Gary S Solomon, Scott L Zuckerman
OBJECTIVES: This study investigated the relationship between on-field, objective signs immediately following sport-related concussion and self-reported symptom endorsement within 1 day post injury. METHODS: A retrospective case series of 237 concussed high school athletes was performed. On-field signs were evaluated immediately post injury. Self-reported symptoms (2 clusters) were collected within 1 day post injury. A two-step structural equation model and follow-up bivariate regression analyses of significant on-field signs and symptom clusters were performed...
January 8, 2018: Journal of the International Neuropsychological Society: JINS
Kathleen F Pagulayan, Holly Rau, Renee Madathil, Madeleine Werhane, Steven P Millard, Eric C Petrie, Brett Parmenter, Sarah Peterson, Scott Sorg, Rebecca Hendrickson, Cindy Mayer, James S Meabon, Bertrand R Huber, Murray Raskind, David G Cook, Elaine R Peskind
OBJECTIVES: To evaluate prospective and retrospective memory abilities in Operation Enduring Freedom (OEF), Operation Iraqi Freedom (OIF), and Operation New Dawn (OND) Veterans with and without a self-reported history of blast-related mild traumatic brain injury (mTBI). METHODS: Sixty-one OEF/OIF/OND Veterans, including Veterans with a self-reported history of blast-related mTBI (mTBI group; n=42) and Veterans without a self-reported history of TBI (control group; n=19) completed the Memory for Intentions Test, a measure of prospective memory (PM), and two measures of retrospective memory (RM), the California Verbal Learning Test-II and the Brief Visuospatial Memory Test-Revised...
December 29, 2017: Journal of the International Neuropsychological Society: JINS
Umesh M Venkatesan, Elena K Festa, Brian R Ott, William C Heindel
OBJECTIVES: Patients with Alzheimer's disease (AD) demonstrate deficits in cross-cortical feature binding distinct from age-related changes in selective attention. This may have consequences for driving performance given its demands on multisensory integration. We examined the relationship of visuospatial search and binding to driving in patients with early AD and elderly controls (EC). METHODS: Participants (42 AD; 37 EC) completed search tasks requiring either luminance-motion (L-M) or color-motion (C-M) binding, analogs of within and across visual processing stream binding, respectively...
December 28, 2017: Journal of the International Neuropsychological Society: JINS
Clare L Kempnich, Sophie C Andrews, Fiona Fisher, Dana Wong, Nellie Georgiou-Karistianis, Julie C Stout
OBJECTIVES: People with Huntington's disease (HD) experience poor social quality of life, relationship breakdown, and social withdrawal, which are mediated to some extent by socially debilitating neuropsychiatric symptoms, such as apathy and disinhibition. Social cognitive symptoms, such as impaired emotion recognition, also occur in HD, however, the extent of their association with these socially debilitating neuropsychiatric symptoms is unknown. Our study examined the relationship between emotion recognition and symptom ratings of apathy and disinhibition in HD...
December 28, 2017: Journal of the International Neuropsychological Society: JINS
François Osiurak, Marine Granjon, Isabelle Bonnevie, Joël Brogniart, Laura Mechtouff, Amandine Benoit, Norbert Nighoghossian, Mathieu Lesourd
OBJECTIVES: Recent evidence indicates that some left brain-damaged (LBD) patients have difficulties to use familiar tools because of the inability to reason about physical object properties. A fundamental issue is to understand the residual capacity of those LBD patients in tool selection. METHODS: Three LBD patients with tool use disorders, three right brain-damaged (RBD) patients, and six matched healthy controls performed a novel tool selection task, consisting in extracting a target out from a box by selecting the relevant tool among eight, four, or two tools...
December 26, 2017: Journal of the International Neuropsychological Society: JINS
Christa L Watson, Katherine Possin, I Elaine Allen, H Isabel Hubbard, Marita Meyer, Ariane E Welch, Gil D Rabinovici, Howard Rosen, Katherine P Rankin, Zachary Miller, Miguel A Santos-Santos, Joel H Kramer, Bruce L Miller, Maria Luisa Gorno-Tempini
OBJECTIVES: The aim of this study was to identify whether the three main primary progressive aphasia (PPA) variants would show differential profiles on measures of visuospatial cognition. We hypothesized that the logopenic variant would have the most difficulty across tasks requiring visuospatial and visual memory abilities. METHODS: PPA patients (n=156), diagnosed using current criteria, and controls were tested on a battery of tests tapping different aspects of visuospatial cognition...
March 2018: Journal of the International Neuropsychological Society: JINS
Amanda R Rabinowitz, Tessa Hart, John Whyte, Junghoon Kim
OBJECTIVES: The goal of the present study was to elucidate the influence of demographic and neuropathological moderators on the longitudinal trajectory neuropsychological functions during the first year after moderate to severe traumatic brain injury (TBI). In addition to examining demographic moderators such as age and education, we included a measure of whole-brain diffuse axonal injury (DAI), and examined measures of processing speed (PS), executive function (EF), and verbal learning (VL) separately...
March 2018: Journal of the International Neuropsychological Society: JINS
Shanna L Burke, Miriam J Rodriguez, Warren Barker, Maria T Greig-Custo, Monica Rosselli, David A Loewenstein, Ranjan Duara
OBJECTIVES: The aim of this study was to determine the presence and severity of potential cultural and language bias in widely used cognitive and other assessment instruments, using structural MRI measures of neurodegeneration as biomarkers of disease stage and severity. METHODS: Hispanic (n=75) and White non-Hispanic (WNH) (n=90) subjects were classified as cognitively normal (CN), amnestic mild cognitive impairment (aMCI) and mild dementia. Performance on the culture-fair and educationally fair Fuld Object Memory Evaluation (FOME) and Clinical Dementia Rating Scale (CDR) between Hispanics and WNHs was equivalent, in each diagnostic group...
February 2018: Journal of the International Neuropsychological Society: JINS
Zac Houck, Breton Asken, James Clugston, William Perlstein, Russell Bauer
OBJECTIVES: The purpose of this study was to assess the contribution of socioeconomic status (SES) and other multivariate predictors to baseline neurocognitive functioning in collegiate athletes. METHODS: Data were obtained from the Concussion Assessment, Research and Education (CARE) Consortium. Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) baseline assessments for 403 University of Florida student-athletes (202 males; age range: 18-23) from the 2014-2015 and 2015-2016 seasons were analyzed...
January 2018: Journal of the International Neuropsychological Society: JINS
Brandon P Vasquez, Malcolm A Binns, Nicole D Anderson
OBJECTIVES: Intraindividual variability increases with age, but the relative strength of association with cognitive domains is still unclear. The objective of this study was to examine the relation between cognitive domains and the shape and spread of response time (RT) distributions as indexed by intraindividual standard deviation (ISD), and ex-Gaussian parameters (μ, σ, τ). METHODS: Healthy adults (40 young [aged 18-30 years], 40 young-old [aged 65-74 years], and 41 old-old [aged 75-85 years]) completed neuropsychological testing and a touch-screen attention task from which ISD and ex-Gaussian parameters were derived...
December 6, 2017: Journal of the International Neuropsychological Society: JINS
Jennifer J Vasterling, Mihaela Aslan, Lewina O Lee, Susan P Proctor, John Ko, Shawna Jacob, John Concato
OBJECTIVES: Military deployment is associated with increased risk of adverse emotional and cognitive outcomes. Longitudinal associations involving posttraumatic stress disorder (PTSD), relatively mild traumatic brain injury (TBI), and neurocognitive compromise are poorly understood, especially with regard to long-term outcomes, and rigorous research is necessary to better understand the corresponding relationships. The objective of this study was to examine short-term and long-term (>5 years) longitudinal associations among PTSD, neurocognitive performance, and TBI following military deployment...
December 4, 2017: Journal of the International Neuropsychological Society: JINS
Natascia De Lucia, Dario Grossi, Graziella Milan, Luigi Trojano
OBJECTIVES: Alzheimer's disease (AD) patients may show the Closing-in (CI), a tendency to reproduce figures close to or superimposed on the model. AD patients with CI might manifest reduced functional independence compared to AD patients without CI, but no study directly assessed if CI can hamper common daily living activities. To address this issue here we investigated whether AD patients with CI veer their walking trajectory toward irrelevant objects more often than AD patients without CI...
December 4, 2017: Journal of the International Neuropsychological Society: JINS
Antonia F Ten Brink, Johanna M A Visser-Meily, Tanja C W Nijboer
OBJECTIVES: Stroke could lead to deficits in organization of visual search. Cancellation tests are frequently used in standard neuropsychological assessment and appear suitable to measure search organization. The current aim was to evaluate which cognitive functions are associated with cancellation organization measures after stroke. METHODS: Stroke patients admitted to inpatient rehabilitation were included in this retrospective study. We performed exploratory factor analyses to explore cognitive domains...
December 4, 2017: Journal of the International Neuropsychological Society: JINS
Aurore Etchepare, Antoinette Prouteau
OBJECTIVE: Social cognition has received growing interest in many conditions in recent years. However, this construct still suffers from a considerable lack of consensus, especially regarding the dimensions to be studied and the resulting methodology of clinical assessment. Our review aims to clarify the distinctiveness of the dimensions of social cognition. METHOD: Based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statements, a systematic review was conducted to explore the factor structure of social cognition in the adult general and clinical populations...
November 27, 2017: Journal of the International Neuropsychological Society: JINS
Wesley R Cole, Emma Gregory, Jacques P Arrieux, F Jay Haran
OBJECTIVES: The Automated Neuropsychological Assessment Metrics 4 TBI-MIL (ANAM4) is a computerized cognitive test often used in post-concussion assessments with U.S. service members (SMs). However, existing evidence remains mixed regarding ANAM4's ability to identify cognitive issues following mild traumatic brain injury (mTBI). Studies typically examine ANAM4 using standardized scores and/ or comparisons to a baseline. A more fine-grained approach involves examining inconsistency within an individual's performance (i...
November 23, 2017: Journal of the International Neuropsychological Society: JINS
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