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Asian Cardiovascular & Thoracic Annals

Hiroaki Harada, Kazuaki Miyamaoto, Masami Kimura, Tetsuro Ishigami, Kiyomi Taniyama, Morihito Okada
BACKGROUND: Assuming that the entire airway is affected by the same inhaled carcinogen, similar molecular alterations may occur in the lung and oral cavity. Thus, we hypothesized that DNA methylation profiles in the oral epithelium may be a promising biomarker for lung cancer risk stratification. METHODS: A methylation-specific polymerase chain reaction was performed on oral epithelium from 16 patients with lung cancer and 32 controls without lung cancer. Genes showing aberrant methylation profiles in the oral epithelium were compared between patients and controls...
November 11, 2018: Asian Cardiovascular & Thoracic Annals
Richard D Mainwaring, William L Patrick, Tatiana R Rosenblatt, Teimour Nasirov, Komal Kamra, Frank L Hanley
OBJECTIVE: Pulmonary atresia with ventricular septal defect and major aortopulmonary collateral arteries is a complex form of congenital heart disease. Midline unifocalization has been developed for the surgical treatment of this condition. There are 3 outcome measures that determine long-term success: patients are alive, patients have achieved complete repair (i.e. ventricular septal defect closure), and patients have a relatively low right ventricle-to-aortic pressure ratio (<0.45)...
November 11, 2018: Asian Cardiovascular & Thoracic Annals
Toshitaka Watanabe, Ryo Harada, Takuma Mikami, Ryosuke Numaguchi, Hirosato Doi, Nobuyoshi Kawaharada
Alkaptonuria is a rare disorder of amino acid metabolism that causes premature large joint spine arthropathy and cardiac disease. We describe a case of aortic stenosis and coronary artery disease associated with ochronosis in a 76-year-old man who underwent aortic valve replacement and coronary artery bypass grafting. Although the ochronosis was extensive, no ochronosis was seen in the internal thoracic artery which used for coronary artery bypass grafting. Ochronosis with alkaptonuria is considered to accelerate the atherosclerotic process, so the internal thoracic artery may ensure a better long-term outcome...
November 11, 2018: Asian Cardiovascular & Thoracic Annals
Shinsuke Uchida, Koji Tsuta, Masahiko Kusumoto, Kouya Shiraishi, Takashi Kohno, Shun-Ichi Watanabe
Pulmonary collision tumors have been described as a special entity of synchronous multiple lung cancer. There have been no reports detailing the chronological changes in primary collision lung cancers on chest computed tomography. We report a case of ground-glass lung nodules gradually colliding with each other. The collision tumors of the lung were composed of minimally invasive adenocarcinoma and adenocarcinoma in situ with epidermal growth factor mutations. Immunohistochemically, the Ki-67 labeling indices were different in the 2 components...
November 11, 2018: Asian Cardiovascular & Thoracic Annals
Constantine Marios Soultanis, Ma Chenchao, Jiang Lei
Segmentectomy is gaining popularity for the treatment of lung cancer, especially in the early stages. Comprehensive understanding of segmental and subsegmental anatomy is required for the procedure to be successfully completed from a technical and oncological point of view. We hereby present a novel technique for delineating the intersegmental border, which can be widely reproduced because it is not time-consuming and does not require special equipment.
November 11, 2018: Asian Cardiovascular & Thoracic Annals
George Whittaker, Abdullatif Aydin, Sinthuri Raveendran, Faizan Dar, Prokar Dasgupta, Kamran Ahmed
BACKGROUND: Training for robot-assisted thoracic lobectomy remains an issue, prompting the development of virtual reality simulators. Our aim was to assess the construct and face validity of a new thoracic lobectomy module on the RobotiX Mentor, a robotic surgery simulator. We also aimed to determine the acceptability and feasibility of implementation into training. METHODS: This prospective, observational, and comparative study recruited novice (n = 16), intermediate (n = 9), and expert (n = 5) participants from King's College London, the 25th European Conference on General Thoracic Surgery, and the Society of Robotic Surgery conference 2018...
November 11, 2018: Asian Cardiovascular & Thoracic Annals
Hina Inam, Ibrahim Zahid, Saulat Fatimi
Tracheal diverticula are rare benign entities characterized by small air-filled invaginations in the paratracheal area. They may be single or multiple, and usually present with nonspecific symptoms. Ideally, computed tomography imaging studies are used to confirm the diagnosis, followed by surgical resection as the treatment of choice. We present the case of a woman with an acquired tracheal diverticulum, with dysphagia as the only presenting symptom.
November 11, 2018: Asian Cardiovascular & Thoracic Annals
Maria E Serrano-Teruel, Maria Garcia-Vieites, Ignacio Rego-Perez, Nieves Domenech-Garcia, Francisco Blanco-Garcia, Jose J Cuenca-Castillo, Victor Bautista-Hernandez
AIM: The underlying pathophysiologic mechanisms of aortic stenosis are not clear. Mitochondrial dysfunction plays a role in many pathological conditions including cardiac diseases. We aimed to analyze the mitochondrial DNA haplogroups in a group of patients undergoing valve replacement surgery due to severe aortic stenosis. METHODS: Mitochondrial DNA haplogroups were assessed in 176 patients with severe aortic stenosis and 308 control subjects. Cardiovascular risk factors and demographics were similar in both groups...
November 8, 2018: Asian Cardiovascular & Thoracic Annals
Yasuyuki Kobayashi, Yasuhiro Kotani, Yosuke Kuroko, Sadahiko Arai, Shingo Kasahara
An 8-year-old girl with no history of chest pain or exertional dyspnea was admitted for atrial septal defect closure. Transthoracic echocardiography showed a sac in the right atrium, protruding from the left ventricle. A left ventricular aneurysm was confirmed by cardiac catheterization. At surgery, the protruding saccular aneurysm arising from the left ventricle was located between the atrial septal defect and the tricuspid valve. We closed the orifice with interrupted sutures from the right atrium. The atrial septal defect was closed with an autologous pericardial patch...
October 31, 2018: Asian Cardiovascular & Thoracic Annals
Andrea De Martino, Giosuè Falcetta, Giovanni Scioti, Angela Pucci, Uberto Bortolotti
A 42-year-old woman, with no evidence of connective tissue disease, presented with acute aortic dissection after an uneventful vaginal delivery following an uncomplicated pregnancy. Emergency computed tomography angiography showed a bovine aortic arch with a separate origin of the left vertebral artery. At surgery, a tricuspid aortic valve was found and the aortic arch was successfully repaired with reimplantation of a button incorporating the origin of the brachiocephalic vessels. Acute aortic dissection throughout pregnancy is uncommon and favoured by hemodynamic, hormonal, and histological changes...
October 31, 2018: Asian Cardiovascular & Thoracic Annals
Aya Harada Takeda, Toshiyuki Nagata, Yuto Nonaka, Nobuhiro Imamura, Shoichiro Morizono, Masami Sato
A 46-year-old woman was found to have an aneurysm of the superior segmental pulmonary artery in the right lower lung lobe on computed tomography images. Moreover, angiography revealed dilated bronchial arteries flowing into the aneurysm with neovascularization, and the contrast medium was partially pooled in the basal segment of the same lobe. The patient's hemoptysis could not be controlled by an interventional radiology procedure. Therefore, lobectomy was carried out instead of aneurysmectomy. There has been no recurrence for 4 years after surgery...
October 22, 2018: Asian Cardiovascular & Thoracic Annals
Ali Sadeghpour Tabaie, Mohaddeseh Behjati, Hojjat Mortezaeian, Hamid Reza Pouraliakbar, Behshid Ghadrdoost, Bahador Baharestani
A 4-year-old boy developed dyspnea 18 months after attempted surgical patent ductus arteriosus closure using a clip that was inadvertently placed on the left pulmonary artery, followed by reoperation to repair the left pulmonary artery with a patch and re-close the ductus. Computed tomography angiography confirmed a large patent ductus arteriosus, left pulmonary artery occlusion, and patent left pulmonary veins. Therefore, a third surgery was performed for suture closure of the ductus and left pulmonary artery repair with an interposition tube graft...
October 22, 2018: Asian Cardiovascular & Thoracic Annals
Gyoten Takayuki, Oliver Grimmig, Just Sören, Fritzsche Dirk
Device dislocation associated with left atrial appendage closure with a Watchman device is rare. Few cases of surgical treatment have been reported. Therefore, surgical options and the effects of the surgery on subsequent operations are unknown. This device was implanted in 2 patients in another hospital because of frequent brain and intestinal bleeding related to coagulation therapy for atrial fibrillation. However, routine echocardiography revealed dislocation from the left atrial appendage orifice in the early and late postoperative periods...
October 3, 2018: Asian Cardiovascular & Thoracic Annals
Niravkumar K Sangani, Santosh Mathew Naliath
A 37-year-old man underwent mechanical mitral valve replacement for rheumatic heart disease. One week after discharge, he presented with high-grade fever with chills, malaise, and shortness of breath. Echocardiography showed pericardial effusion with no evidence of vegetation. A blood malaria antigen test was positive for Plasmodium falciparum. One week after initiation of antimalarial medication, echocardiography revealed almost complete resolution of the pericardial effusion. Infective endocarditis is a common cause of fever after valvular heart surgery...
September 30, 2018: Asian Cardiovascular & Thoracic Annals
Kazuhiko Ishimaru, Kanta Araki, Shigeru Sakamoto, Yoshiki Sawa
A 4-year-old girl with pulmonary regurgitation after complete repair of tetralogy of Fallot, underwent an alternative surgical repair for pulmonary valve replacement. Hand-sewn trileaflet valve reconstruction using expanded polytetrafluoroethylene membrane is a feasible method for pulmonary regurgitation in such a young child in whom a large-sized bioprosthetic valve cannot be implanted.
September 24, 2018: Asian Cardiovascular & Thoracic Annals
Alfonso Campanile, Mariagrazia Sardone, Stefano Pasquino, Angelo Cagini, Gino Di Manici, Claudio Cavallini
The ascending aorta is an uncommon site of noninfective thrombus. We describe the case of a 63-year-old woman who was admitted to our department with acute myocardial infarction. Coronary angiography showed occlusion of a small diagonal vessel, likely related to a distal embolization event. A transthoracic echocardiogram revealed a free-floating mass in the proximal ascending aorta. Two-and 3-dimensional transesophageal echocardiography studies were performed, and after a multidisciplinary heart team discussion, surgical removal of the mass was planned and successfully performed through a median sternotomy on cardiopulmonary bypass...
September 24, 2018: Asian Cardiovascular & Thoracic Annals
Frank Farfán-Leal, Amparo Esteban, Rocío Hinojar, Mónica García-Cosío, Francisco Contreras
Extranodal natural killer/T-cell lymphoma is a rare non-Hodgkin lymphoma that is divided into nasal, non-nasal, and aggressive/leukemia subtypes, according to anatomic origin and clinical manifestations, with each subtype carrying a different prognosis. We present a case of primary cardiac natural killer/T-cell lymphoma with extension to other organs in a 38-year-old man, to highlight the role of imaging in categorizing nasal versus non-nasal types. This distinction has relevant implications for patient care because the non-nasal type has a much lower survival rate...
September 12, 2018: Asian Cardiovascular & Thoracic Annals
Vijayakumar Raju, Aayush Poddar, Sai Gopalakrishnan, Kalyanasundaram Muthuswamy
Delayed migration of a ductal occluder device into the aorta after transcatheter closure of a patent ductus arteriosus is extremely rare. We present a case of delayed migration of a ductal occluder into the descending aorta 4 months after its deployment in an 11-year-old girl. Successful surgical removal of the device from the descending aorta and triple-ligation of the ductus arteriosus was performed via a left thoracotomy. The patient made an uneventful recovery.
September 7, 2018: Asian Cardiovascular & Thoracic Annals
Pietro Giorgio Malvindi, Daniela Votano, Ahmed Ashoub, Amit Modi, Szabolcs Miskolczi, Theodore Velissaris, Clifford Barlow, Sunil Ohri, Geoffrey Tsang, Steven Livesey, Laszlo Göbölös
BACKGROUND: We evaluated the clinical and anatomic presentations of acute type A aortic dissection according to patient age. METHODS: We retrospectively reviewed 235 consecutive patients who underwent acute type A dissection repair between January 2000 and December 2014. The influence of age on anatomical and clinical presentation, surgical management in the entire cohort and also after exclusion of patients with known connective tissue disorders was assessed using logistic regression...
November 2018: Asian Cardiovascular & Thoracic Annals
Bineesh K Radhakrishnan, Paritosh Ballal, Jayakumar Karunakaran
No abstract text is available yet for this article.
November 2018: Asian Cardiovascular & Thoracic Annals
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