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Journal of Cardiac Failure

Emmanuelle Berthelot, David Montani, Vincent Algalarrondo, Céline Dreyfus, Raed Rifai, Anouar Benmalek, Xavier Jais, Amir Bouchachi, Laurent Savale, Gerald Simonneau, Denis Chemla, Marc Humbert, Olivier Sitbon, Patrick Assayag
BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a frequent cause of pulmonary hypertension (PH) that is not easy to differentiate from precapillary PH. We aimed to determine whether the characteristic features of the patients may help differentiate between HFpEF and precapillary-PH. METHODS AND RESULTS: Clinical and echocardiographic parameters were analyzed in 156 patients referred to our PH referral center. Right heart catheterization identified 78 PH-HFpEF patients and 78 precapillary-PH...
October 11, 2016: Journal of Cardiac Failure
Nisha A Gilotra, Adam Shpigel, Ike S Okwuosa, Ruth Tamrat, Deirdre Flowers, Stuart D Russell
BACKGROUND: There is a paucity of data describing patient-identified precipitants of heart failure (HF) hospitalization. We hypothesized a patient's perception of reason for or preventability of an admission may be related to 30-day readmission rates. METHODS AND RESULTS: Ninety-four patients admitted with decompensated HF from July 2014 to March 2015 completed a brief questionnaire regarding circumstances leading to admission. Thirty-day outcomes were assessed via telephone call and chart review...
October 11, 2016: Journal of Cardiac Failure
Masaru Obokata, Yasufumi Nagata, Yuichiro Kado, Masahiko Kurabayashi, Yutaka Otsuji, Masaaki Takeuchi
BACKGROUND: Exercise-induced pulmonary hypertension (EIPH) may develop even at low workloads in heart failure (HF) patients. Ventricular-arterial stiffening plays an important role in the pathophysiology of HF with preserved ejection fraction (HFpEF). This study aimed to compare the response of ventricular-arterial coupling and PH during low-level exercise between HFpEF and HF with reduced EF (HFrEF). METHODS AND RESULTS: Echocardiography was performed at rest and during 10 W of bicycle exercise in HFpEF (n=37) and HFrEF (n=43)...
October 10, 2016: Journal of Cardiac Failure
Pieter Martens, Frederik H Verbrugge, Petra Nijst, Matthias Dupont, Wilfried Mullens
BACKGROUND: Cardiac resynchronization therapy (CRT) improves morbidity and mortality in heart failure with reduced ejection fraction (HFrEF) and electrical dyssynchrony. CRT patients in clinical practice are older compared to clinical trials. OBJECTIVE: To investigate clinical response, reverse remodeling, outcome and mode of death in octogenarians receiving CRT. METHODS: Baseline characteristics, change in New York Heart Association (NYHA) functional class, reverse ventricular remodeling, heart failure readmissions, all-cause mortality and mode of death were evaluated in CRT patients with comparison between octogenarians and non-octogenarians...
October 4, 2016: Journal of Cardiac Failure
Christopher Holley
No abstract text is available yet for this article.
September 30, 2016: Journal of Cardiac Failure
Walter J Paulus
No abstract text is available yet for this article.
September 30, 2016: Journal of Cardiac Failure
Mahmoud U Sani, Gad Cotter, Beth A Davison, Bongani M Mayosi, Albertino Damasceno, Christopher Edwards, Okechukwu S Ogah, Charles Mondo, Anastase Dzudie, Dike B Ojji, Charles Kouam Kouam, Ahmed Suliman, Gerald Yonga, Sergine Abdou Ba, Fikru Maru, Bekele Alemayehu, Karen Sliwa
BACKGROUND: Symptoms and signs of heart failure (HF) are the most common reasons for admission to hospital for acute HF (AHF) and are used routinely throughout admission, to assess the severity of disease and response to therapy. METHODS AND RESULTS: The data were collected in the sub Saharan Africa survey on heart failure (THESUS-HF) study, a prospective, multicenter, observational survey of AHF, from 9 countries in sub-Saharan Africa. 1006 patients, 12 years or older, hospitalized for acute heart failure were recruited...
September 21, 2016: Journal of Cardiac Failure
Sue J Wingate
No abstract text is available yet for this article.
September 21, 2016: Journal of Cardiac Failure
Frederic S Michel, Mhlengi Magubane, Lebogang Mokotedi, Gavin R Norton, Angela J Woodiwiss
AIM: To determine whether adrenergic-induced left ventricular (LV) dilatation and eccentric remodeling in pressure-overload hypertrophy is sex-specific. METHODS AND RESULTS: Chronic β-adrenoreceptor activation was produced in male and female spontaneously hypertensive rats (SHR) by daily administration of isoproterenol (ISO, 0.04 mg/ from 9 to 15 months of age. LV chamber dimensions were determined in vivo by echocardiography and ex vivo in isolated perfused heart preparations...
September 20, 2016: Journal of Cardiac Failure
Daniel J Lenihan, Susan Dent, Joseph Carver
No abstract text is available yet for this article.
September 20, 2016: Journal of Cardiac Failure
Yuya Matsue, Jozine M Ter Maaten, Joachim Struck, Marco Metra, Christopher M O'Connor, Piotr Ponikowski, John R Teerlink, Gad Cotter, Beth Davison, John G Cleland, Michael M Givertz, Daniel M Bloomfield, Howard C Dittrich, Dirk J van Veldhuisen, Peter van der Meer, Kevin Damman, Adriaan A Voors
BACKGROUND: Proenkephalin (pro-ENK) has emerged as a novel biomarker associated with both renal function and cardiac function. However, its clinical and prognostic value have not been well evaluated in symptomatic patients with heart failure. METHODS AND RESULTS: The association between pro-ENK and markers of renal function was evaluated in 95 patients with chronic heart failure who underwent renal hemodynamic measurements including renal blood flow (RBF) and glomerular filtration rate (GFR) using(131)I-Hippuran and (125)I-Iothalamate clearances, respectively...
September 20, 2016: Journal of Cardiac Failure
Mandeep R Mehra
No abstract text is available yet for this article.
September 19, 2016: Journal of Cardiac Failure
A Perciaccante, M A Riva, A Coralli, P Charlier, R Bianucci
Overweight, workaholic, and a caffeine abuser, Honoré de Balzac lived a life of excess. He prematurely died at the age of 51 owing to gangrene associated with congestive heart failure. Textual sources allow us to take a glimpse into his last 3 months of life. Because of ventricular hypertrophy, Balzac's respiratory conditions were appalling and he developed severe leg edemas and possibly stasis dermatitis. Here we report on Balzac's demise and provide first evidence of a pioneering medical treatment applied to save his life: the use of a trocar to drain leg edema...
September 13, 2016: Journal of Cardiac Failure
Kevin Damman, Serge Masson, Donata Lucci, Marco Gorini, Renato Urso, Aldo P Maggioni, Luigi Tavazzi, Luigi Tarantini, Gianni Tognoni, Adriaan Voors, Roberto Latini
BACKGROUND: Data on the natural change in renal function in patients with chronic heart failure (HF) is limited. METHODS AND RESULTS: Estimated glomerular filtration rate (eGFR) was assessed over 36 months in 6934 patients included in the GISSI-HF study. Association between baseline, changes in renal function and occurrence of Cardiovascular Death or HF hospitalization was assessed. Mean age was 67 years, mainly males (78%) and mean eGFR was 68 mL/min/1.73m(2). Change in eGFR in the first year was -1...
September 13, 2016: Journal of Cardiac Failure
W David Xu, James C Fang
No abstract text is available yet for this article.
September 9, 2016: Journal of Cardiac Failure
Eiichi Watanabe, Ken Kiyono, Shojiro Matsui, Virend K Somers, Kan Sano, Junichiro Hayano, Tomohide Ichikawa, Mayumi Kawai, Masahide Harada, Yukio Ozaki
BACKGROUND: Sleep-disordered breathing, particularly central sleep apnea (CSA), is highly prevalent in heart failure (HF) and an independent prognostic marker. We assessed the hypothesis that an increased hypoxemic burden during sleep may have greater prognostic value than the frequency of apneic and hypopneic episodes. METHODS AND RESULTS: We prospectively conducted overnight cardiorespiratory polygraphy on consecutive HF patients referred to our hospital from 2008 to 2011...
September 9, 2016: Journal of Cardiac Failure
Meredith A Brisco-Bacik
No abstract text is available yet for this article.
September 8, 2016: Journal of Cardiac Failure
Eugene S Chung, Gregory F Egnaczyk
No abstract text is available yet for this article.
September 7, 2016: Journal of Cardiac Failure
Brian D Steinhart, Phillip Levy, Hilde Vandenberghe, Gordon Moe, Andrew T Yan, Ashley Cohen, Kevin E Thorpe, Melissa McGowan, C David Mazer
BACKGROUND: Diagnosing acute heart failure (AHF) in undifferentiated dyspneic emergency department (ED) patients can be challenging. We prospectively studied a validated diagnostic prediction model for AHF that uses patient age, clinician pretest probability for AHF, and N-terminal pro-B-type natriuretic peptide (NT-proBNP) as a continuous value to determine its utility and performance. METHODS AND RESULTS: This was a multicenter randomized controlled trial of undifferentiated dyspneic patients with an indeterminate pretest probability of AHF as assessed by the treating emergency physician (EP)...
August 24, 2016: Journal of Cardiac Failure
Ayodele Odutayo, Christopher X Wong, Rashida Williams, Benjamin Hunn, Connor A Emdin
BACKGROUND: Atrial fibrillation (AF) is common among adults with congestive heart failure (CHF). We conducted a meta-analysis to summarize the risk of mortality and cardiovascular disease associated with AF in CHF and stratified our analyses by AF timing and pattern. METHODS: We searched MEDLINE and EMBASE for observational studies examining the association of AF with cardiovascular disease and death. Eligible studies had a minimum of 50 participants with AF and 50 participants without AF, and a median follow-up of 6 months...
August 24, 2016: Journal of Cardiac Failure
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