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Journal of Cardiac Failure

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https://www.readbyqxmd.com/read/27908780/complexity-of-sympathetic-nerve-traffic-in-human-heart-failure-seeking-inspiration
#1
EDITORIAL
John S Floras, Noe Zamel
No abstract text is available yet for this article.
November 28, 2016: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/27890771/echocardiographic-determinants-of-one-year-all-cause-mortality-in-patients-with-chronic-heart-failure-complicated-by-significant-functional-tricuspid-regurgitation
#2
Kai Hu, Dan Liu, Stefan Störk, Sebastian Herrmann, Daniel Oder, Georg Ertl, Wolfram Voelker, Frank Weidemann, Peter Nordbeck
BACKGROUND: Right ventricular (RV) dysfunction plays an important role in chronic heart failure (CHF). We evaluated the echocardiographic determinants of one-year all-cause mortality in CHF patients with clinically relevant functional tricuspid regurgitation (TR). METHODS AND RESULTS: A total of 101 consecutive CHF patients (mean age 74±10 years; 53% male) with moderate/severe functional TR were enrolled. Each patient underwent at least two echocardiography examinations in an interval >6 months...
November 24, 2016: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/27890770/fibrosis-and-fibrotic-gene-expression-in-pediatric-and-adult-patients-with-idiopathic-dilated-cardiomyopathy
#3
Kathleen C Woulfe, Austine K Siomos, Hieu Nguyen, Megan SooHoo, Csaba Galambo, Brian L Stauffer, Carmen Sucharov, Shelley Miyamoto
BACKGROUND: While fibrosis seems to be prognostic for adverse outcomes in adults with idiopathic dilated cardiomyopathy (IDC), little is known about the prevalence and development of fibrosis in pediatric IDC hearts. We hypothesize there is less activation of fibrosis at a molecular level in pediatric IDC hearts than in the failing adult heart. METHODS AND RESULTS: Pediatric hearts were analyzed histologically to determine the prevalence of fibrosis. Left ventricular tissue from adult and pediatric IDC hearts and adult and pediatric non-failing (NF) hearts were subjected to qRT-PCR to study the expression of important mRNAs that affect fibrosis...
November 24, 2016: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/27888066/looking-back-at-baltimore-1997
#4
EDITORIAL
Paul J Hauptman
No abstract text is available yet for this article.
November 22, 2016: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/27867115/central-chemoreceptor-sensitivity-is-not-enhanced-in-contemporary-patients-with-chronic-systolic-heart-failure-receiving-optimal-treatment
#5
Bartłomiej Paleczny, Martyna Olesińska, Agnieszka Siennicka, Piotr Niewiński, Ewa A Jankowska, Beata Ponikowska, W Banasiak, Stephan von Haehling, Stefan D Anker, Piotr Ponikowski
BACKGROUND: Clinical and prognostic consequences of enhanced central chemosensitivity in the contemporary optimally treated patients with chronic heart failure (CHF) are unknown. METHODS AND RESULTS: We studied central chemosensitivity (defined as the ventilatory response to hypercapnia assessed by the rebreathing method, HCVR [L/min/mmHg]) in 161 CHF patients (mean left ventricular ejection fraction [LVEF]: 31±6%, all receiving a combination of angiotensin-converting enzyme inhibitor/angiotensin receptor blocker and beta-blocker) and 55 sex-, age-matched healthy controls...
November 17, 2016: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/27864030/incident-heart-failure-and-cognitive-decline-the-atherosclerosis-risk-in-communities-study
#6
Jan Bressler, David S Knopman, A Richey Sharrett, Rebecca F Gottesman, Alan Penman, Patricia P Chang, Wayne D Rosamond, Eric Boerwinkle, Thomas H Mosley
BACKGROUND: Cognitive impairment is found in a significant proportion of patients with heart failure (HF). While cognitive impairment may be a consequence of HF, early signs of cognitive impairment may also indicate subclinical vascular disease, and thus a risk factor for future cardiovascular events. METHODS AND RESULTS: The Atherosclerosis Risk in Communities Study is a prospective cohort study of the development of atherosclerosis. Cox proportional hazards regression was used to examine the association between mean 6-year change in cognitive function and incident HF in 7,962 white and 1,933 African-American men and women aged 46 to 70 years and free of clinical stroke...
November 15, 2016: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/27825893/evaluating-the-efficacy-safety-and-tolerability-of-serelaxin-when-added-to-standard-therapy-in-asian-patients-with-acute-heart-failure-the-design-and-rationale-of-relax-ahf-asia-trial
#7
Naoki Sato, Carolyn S P Lam, John R Teerlink, Barry H Greenberg, Hiroyuki Tsutsui, Byung-Hee Oh, Jian Zhang, Martin Lefkowitz, Tsushung A Hua, Thomas Holbro, Miriam Marshood, Xing Li Wang, Junbo Ge
BACKGROUND: Acute heart failure (AHF), a common and growing health-concern worldwide, is associated with high risk of post-discharge rehospitalization and mortality. Existing evidence indicates potential therapeutic benefits of serelaxin in Caucasian AHF patients, while corresponding data in Asians remain scarce. RELAX-AHF-ASIA, a multinational, randomized, double-blind, placebo-controlled, phase-III trial, will evaluate the effects of serelaxin on symptom relief and clinical outcomes in Asian AHF patients, using novel assessments...
November 4, 2016: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/27818309/telemonitoring-adherence-to-medications-in-heart-failure-patients-team-hf-a-pilot-randomized-clinical-trial
#8
Benjamin D Gallagher, Nathalie Moise, Mytra Haerizadeh, Siqin Ye, Vivian Medina, Ian M Kronish
BACKGROUND: Medication nonadherence contributes to hospitalizations in recently discharged patients with heart failure (HF). We aimed to test the feasibility of telemonitoring medication adherence in patients with HF. METHODS AND RESULTS: We randomized 40 patients (1:1) hospitalized for HF to 30 days of loop diuretic adherence monitoring with telephonic support or to passive adherence monitoring alone. Eighty-three percent of eligible patients agreed to participate...
November 3, 2016: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/27771490/heart-failure-in-older-adults-more-than-just-age
#9
EDITORIAL
Michael W Rich
No abstract text is available yet for this article.
October 19, 2016: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/27769909/skilled-nursing-facility-care-for-patients-with-heart-failure-can-we-make-it-heart-failure-ready
#10
REVIEW
Nicole M Orr, Rebecca S Boxer, Mary A Dolansky, Larry A Allen, Daniel E Forman
Skilled nursing facilities (SNFs) have emerged as an integral component of care for older adults with heart failure (HF). Despite their prominent role, poor clinical outcomes for the medically complex patients with HF managed in SNFs are common. Barriers to providing quality care include poor transitional care during hospital-to-SNF and SNF-to-community discharges, lack of HF training among SNF staff, and a lack of a standardized care process among SNF facilities. Although no evidence-based practice standards have been established, various measures and tools designed to improve HF management in SNFs are being investigated...
October 18, 2016: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/27769908/prognostic-impact-of-living-in-temporary-housing-in-fukushima-after-the-great-east-japan-earthquake
#11
Satoshi Suzuki, Akiomi Yoshihisa, Yuki Kanno, Shunsuke Watanabe, Mai Takiguchi, Shunsuke Miura, Tetsuro Yokokawa, Takamasa Sato, Masayoshi Oikawa, Takayoshi Yamaki, Hiroyuki Kunii, Kazuhiko Nakazato, Hitoshi Suzuki, Shu-Ichi Saitoh, Yasuchika Takeishi
BACKGROUND: Many residents of Fukushima Prefecture were forced to stay in temporary housing due to the Great East Japan Earthquake and the subsequent nuclear power plant accident. The purpose of this study was to examine the prognostic influence in temporary housing in heart failure patients. METHODS AND RESULTS: We investigated 743 hospitalized heart failure patients from March 11, 2011 to September 30, 2014. Among all subjects, 51 patients (6.9%) moved into temporary housing after the earthquake...
October 18, 2016: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/27769907/growing-relevance-of-cardiac-rehabilitation-for-an-older-population-with-heart-failure
#12
REVIEW
David W Schopfer, Daniel E Forman
Cardiac rehabilitation (CR) is a comprehensive lifestyle program that can have particular benefit for older patients with heart failure (HF). Prevalence of HF is increasingly common among older adults. Mounting effects of cardiovascular risk factors in older age as well as the added effects of geriatric syndromes such as multimorbidity, frailty, and sedentariness contribute to the high incidence of HF as well as to management difficulty. CR can play a decisive role in improving function, quality of life, symptoms, morbidity, and mortality, and also address the idiosyncratic complexities of care that often arise in old age...
October 18, 2016: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/27765670/ventricular-assist-device-therapy-in-older-patients-with-heart-failure-characteristics-and-outcomes
#13
Ju H Kim, Ramesh Singh, Francis D Pagani, Shashank S Desai, Nicholas A Haglund, Shannon M Dunlay, Simon Maltais, Keith D Aaronson, John M Stulak, Mary E Davis, Christopher T Salerno, Jennifer A Cowger, Palak Shah
BACKGROUND: Limited data exist on outcomes in patients ≥70 years of age supported with the use of continuous-flow left ventricular assist devices (LVADs). METHODS: Data on 1149 continuous-flow LVAD recipients was queried from the Mechanical Circulatory Support Research Network. Groups were assigned based on age: ≥70 years ("older patients") and <70 years. The primary outcome was survival at one-year based on age grouping. RESULTS: Compared with younger patients (54...
October 17, 2016: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/27765669/cardiac-resynchronization-therapy-in-older-patients-age-is-just-a-number-and-yet-%C3%A2
#14
EDITORIAL
Daniel B Kramer, Daniel A Steinhaus
No abstract text is available yet for this article.
October 17, 2016: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/27765668/heart-failure-care-more-than-just-heart-failure
#15
Susanna Mak
No abstract text is available yet for this article.
October 17, 2016: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/27765667/einstein-the-blind-men-and-the-elephant-making-sense-of-heart-failure-with-preserved-ejection-fraction
#16
EDITORIAL
Scott L Hummel
No abstract text is available yet for this article.
October 17, 2016: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/27742455/a-clinical-and-echocardiographic-score-to-identify-pulmonary-hypertension-due-to-hfpef
#17
Emmanuelle Berthelot, David Montani, Vincent Algalarrondo, Céline Dreyfuss, Raed Rifai, Anouar Benmalek, Xavier Jais, Amir Bouchachi, Laurent Savale, Gerald Simonneau, Denis Chemla, Marc Humbert, Olivier Sitbon, Patrick Assayag
BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a frequent cause of pulmonary hypertension (PH) that is not easy to differentiate from precapillary PH. We aimed to determine whether the characteristic features of the patients may help differentiate between HFpEF and precapillary PH. METHODS AND RESULTS: Clinical and echocardiographic parameters were analyzed in 156 patients referred to our PH referral center. Right heart catheterization identified 78 PH-HFpEF patients and 78 with precapillary PH...
October 11, 2016: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/27742454/patients-commonly-believe-their-heart-failure-hospitalizations-are-preventable-and-identify-worsening-heart-failure-non-adherence-and-a-knowledge-gap-as-reasons-for-admission
#18
Nisha A Gilotra, Adam Shpigel, Ike S Okwuosa, Ruth Tamrat, Deirdre Flowers, Stuart D Russell
BACKGROUND: There is a paucity of data describing patient-identified precipitants of heart failure (HF) hospitalization. We hypothesized a patient's perception of reason for or preventability of an admission may be related to 30-day readmission rates. METHODS AND RESULTS: Ninety-four patients admitted with decompensated HF from July 2014 to March 2015 completed a brief questionnaire regarding circumstances leading to admission. Thirty-day outcomes were assessed via telephone call and chart review...
October 11, 2016: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/27737768/ventricular-arterial-coupling-and-exercise-induced-pulmonary-hypertension-during-low-level-exercise-in-heart-failure-with-preserved-or-reduced-ejection-fraction
#19
Masaru Obokata, Yasufumi Nagata, Yuichiro Kado, Masahiko Kurabayashi, Yutaka Otsuji, Masaaki Takeuchi
BACKGROUND: Exercise-induced pulmonary hypertension (EIPH) may develop even at low workloads in heart failure (HF) patients. Ventricular-arterial stiffening plays an important role in the pathophysiology of HF with preserved ejection fraction (HFpEF). This study aimed to compare the response of ventricular-arterial coupling and PH during low-level exercise between HFpEF and HF with reduced EF (HFrEF). METHODS AND RESULTS: Echocardiography was performed at rest and during 10 W of bicycle exercise in HFpEF (n=37) and HFrEF (n=43)...
October 10, 2016: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/27717763/mode-of-death-in-octogenarians-treated-with-cardiac-resynchronization-therapy
#20
Pieter Martens, Frederik H Verbrugge, Petra Nijst, Matthias Dupont, Wilfried Mullens
BACKGROUND: Cardiac resynchronization therapy (CRT) improves morbidity and mortality in heart failure with reduced ejection fraction (HFrEF) and electrical dyssynchrony. CRT patients in clinical practice are older compared to clinical trials. OBJECTIVE: To investigate clinical response, reverse remodeling, outcome and mode of death in octogenarians receiving CRT. METHODS: Baseline characteristics, change in New York Heart Association (NYHA) functional class, reverse ventricular remodeling, heart failure readmissions, all-cause mortality and mode of death were evaluated in CRT patients with comparison between octogenarians and non-octogenarians...
October 4, 2016: Journal of Cardiac Failure
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