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American Journal of Therapeutics

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https://www.readbyqxmd.com/read/28092285/perioperative-%C3%AE-blockers-in-patients-undergoing-noncardiac-surgery-scientific-misconduct-and-clinical-guidelines
#1
Dhauna Karam, Rohit Arora
BACKGROUND: β-blocker use in perioperative period of noncardiac surgeries has been a topic of debate since many years. Earlier studies conducted in the 90s showed decreased cardiac adverse events and improved postoperative outcomes with β-blocker use. Based on this, the ACCF and ESC published guidelines strongly supporting β-blocker use. But contemporaneous studies conducted revealed conflicting evidence and have also proven some of the earlier studies to be fraudulent. Although ACCF guidelines have been updated to partially reflect the changes, ESC guidelines continue to support β-blocker use...
January 10, 2017: American Journal of Therapeutics
https://www.readbyqxmd.com/read/28092284/persistent-fever-in-medical-intensive-care-unit-evans-syndrome-versus-actinomycotic-osteomyelitis
#2
Amandeep Aujla, Palash Samanta, Gerardo Cabanillas, Hossam Amin
No abstract text is available yet for this article.
January 10, 2017: American Journal of Therapeutics
https://www.readbyqxmd.com/read/28079539/preoperative-ketoconazole-therapy-for-primary-bilateral-adrenocorticotropic-hormone-independent-macronodular-adrenal-hyperplasia-syndrome
#3
Rukma Parthvi, Sunil Mehra
No abstract text is available yet for this article.
January 5, 2017: American Journal of Therapeutics
https://www.readbyqxmd.com/read/28079538/antimicrobial-therapy-for-pyogenic-liver-abscess-secondary-to-streptococcus-intermedius-bacteremia
#4
Rukma Parthvi, Mohsena Amin, Sunil Mehra
No abstract text is available yet for this article.
January 5, 2017: American Journal of Therapeutics
https://www.readbyqxmd.com/read/28072595/fluoroquinolone-associated-muscle-tear-and-hematoma-a-case-report
#5
Ghulam Murtaza, Boonphiphop Boonpheng
No abstract text is available yet for this article.
December 28, 2016: American Journal of Therapeutics
https://www.readbyqxmd.com/read/28079540/intravenous-immunoglobulin-for-mixed-connective-tissue-disease-presenting-with-bilateral-trigeminal-neuropathy
#6
Abhijeet Danve, Rana Zabad, Alan Erickson
No abstract text is available yet for this article.
December 26, 2016: American Journal of Therapeutics
https://www.readbyqxmd.com/read/28005557/preadmission-diuretic-use-and-mortality-in-patients-hospitalized-with-hyponatremia-a-propensity-score-matched-cohort-study
#7
Louise Holland-Bill, Christian F Christiansen, Sinna P Ulrichsen, Troels Ring, Jens O Lunde Jørgensen, Henrik T Sørensen
BACKGROUND: Hyponatremia is associated with increased mortality and is frequently induced by diuretic use. It is uncertain whether diuretic use is linked to mortality risk in patients with hyponatremia. STUDY QUESTION: To measure the prognostic impact of diuretic use on 30-day mortality among patients hospitalized with hyponatremia. STUDY DESIGN: Using population-based registries, we identified all patients with a serum sodium measurement <135 mmol/L within 24 hours after acute hospital admission in western Denmark from 2006 to 2012 (cumulative population of 2...
December 15, 2016: American Journal of Therapeutics
https://www.readbyqxmd.com/read/27930383/effect-of-e-oj-01-on-cardiac-conditioning-in-young-exercising-adults-a-randomized-controlled-trial
#8
Robert N Girandola, Shalini Srivastava
BACKGROUND AND AIM: Cardiac health is a determinant of athletic performance. A body of data suggests that in healthy young adults, an increase in maximal cardiac output leads to an increase in endurance. Terminalia arjuna (TA) has been studied for multiple benefits in cardiovascular health although its effects as a cardioprotective ergogenic aid require further exploration. The current trial was planned to study the effect of the proprietary TA extract (E-OJ-01) on the markers of cardiac conditioning in healthy young adults...
November 29, 2016: American Journal of Therapeutics
https://www.readbyqxmd.com/read/27984266/unintentional-epinephrine-auto-injector-injuries-a-national-poison-center-observational-study
#9
Marco Anshien, S Rutherfoord Rose, Brandon K Wills
BACKGROUND: Epinephrine is the only first-line therapeutic agent used to treat life-threatening anaphylaxis. Epinephrine auto-injectors are commonly carried by patients at risk for anaphylaxis, and reported cases of unintentional auto-injector injury have increased over the last decade. Modifications of existing designs and release of a new style of auto-injector are intended to reduce epinephrine auto-injector misuse. STUDY QUESTION: The aim of the study was to characterize reported cases of unintentional epinephrine auto-injector exposures from 2013 to 2014 and compare demographics, auto-injector model, and anatomical site of such exposures...
November 24, 2016: American Journal of Therapeutics
https://www.readbyqxmd.com/read/27984264/reducing-restraint-with-clozapine-in-involuntarily-admitted-patients-with-schizophrenia
#10
Petru Ifteni, Andreea S Szalontay, Andreea Teodorescu
BACKGROUND: In the entire world, restraint and seclusion are common interventions in psychiatric inpatient settings because of aggressive behavior. STUDY QUESTION: Our objective was to test for the immediate antiaggressive property of clozapine compared with other antipsychotic treatments in an enriched cohort with high rates of restraint during early hospitalization. METHODS: We present a retrospective chart review in all involuntary admissions with schizophrenia during 2011-2014 in Psychiatry and Neurology Hospital, Brasov, Romania...
November 24, 2016: American Journal of Therapeutics
https://www.readbyqxmd.com/read/27574943/liver-toxicity-from-solifenacin
#11
Umair Masood, Anuj Sharma, Divey Manocha
No abstract text is available yet for this article.
November 24, 2016: American Journal of Therapeutics
https://www.readbyqxmd.com/read/27984265/sulfasalazine-for-inflammatory-arthritis-induced-by-hyaluronic-acid
#12
Shiv T Sehra, Abhijeet Danve
No abstract text is available yet for this article.
November 22, 2016: American Journal of Therapeutics
https://www.readbyqxmd.com/read/27941424/characterization-of-neurologic-and-ophthalmologic-safety-of-oral-administration-of-tedizolid-for-up-to-21-days-in-healthy-volunteers
#13
Edward Fang, Kelly A Muñoz, Philippe Prokocimer
BACKGROUND: Antibacterials that inhibit protein synthesis may be associated with mitochondrial toxicity, manifested as serious optic or peripheral neuropathy or myelosuppression. Tedizolid is a novel oxazolidinone antibacterial that may have reduced the potential for mitochondrial toxicity. STUDY QUESTION: Based on the results of 2 studies (NCT01623401 and NCT00671814) conducted early in the tedizolid development program, what is the potential for drug-induced optic and peripheral neuropathies with tedizolid treatment? METHODS: Two phase-1 studies were conducted in healthy volunteers...
November 15, 2016: American Journal of Therapeutics
https://www.readbyqxmd.com/read/27875371/topiramate-blood-levels-during-polytherapy-for-epilepsy-in-children
#14
Taira Toki, Toshiyuki Iwasaki, Masahiro Ishii
BACKGROUND: The therapeutic range of topiramate (TPM) blood level is not set because the efficacy and safety are not considered to be related to the level. However, the therapeutic target without side effects is necessary, so the optimal range of TPM blood level was analyzed in this study. STUDY QUESTION: This study was conducted to evaluate the efficacy of TPM over 2 years and the utility of measuring blood levels of TPM during the follow-up of epileptic patients...
November 14, 2016: American Journal of Therapeutics
https://www.readbyqxmd.com/read/27875370/myocardial-infarction-after-accidental-minoxidil-poisoning
#15
Ankur Sinha, Hitesh Raheja, Yizhak Kupfer
No abstract text is available yet for this article.
November 14, 2016: American Journal of Therapeutics
https://www.readbyqxmd.com/read/27574944/enterocolitis-an-unknown-side-effect-of-pazopanib
#16
Anuj Sharma, Umair Masood, Divey Manocha
No abstract text is available yet for this article.
November 14, 2016: American Journal of Therapeutics
https://www.readbyqxmd.com/read/27846023/oxygen-administration-does-not-influence-the-prognosis-of-acute-myocardial-infarction-a-meta-analysis
#17
Abdur Rahman Khan, Aref Bin Abdulhak, Faraz Khan Luni, Talha A Farid, Haris Riaz, Mohammed Ruzieh, Long Pham, Glenn Hirsch, Roberto Bolli
BACKGROUND: The safety and efficacy of supplemental oxygen in acute myocardial infarction (AMI) remains unclear. STUDY QUESTION: To evaluate the safety and efficacy of supplemental oxygen in patients who present with AMI. DATA SOURCES: We systematically searched PubMed, Embase, Cochrane Central Register of Controlled Trials, ISI Web of Science, Scopus, and conference proceedings from inception through January 2016. STUDY DESIGN: Eligible studies were randomized trials that evaluated the role of oxygen compared with room air in AMI...
November 2, 2016: American Journal of Therapeutics
https://www.readbyqxmd.com/read/28005556/lamotrigine-associated-hemophagocytic-lymphohistiocytosis
#18
Maya Ignaszewski, Martha J Ignaszewski, Patrick Kohlitz
No abstract text is available yet for this article.
October 31, 2016: American Journal of Therapeutics
https://www.readbyqxmd.com/read/27849633/interactions-between-warfarin-and-prednisolone-a-case-report
#19
T R Peng, L L Lee, T W Wu
No abstract text is available yet for this article.
October 27, 2016: American Journal of Therapeutics
https://www.readbyqxmd.com/read/27779484/intravenous-acetaminophen-for-renal-colic-in-the-emergency-department-where-do-we-stand
#20
Billy Sin, Kimberly Koop, Michelle Liu, Jun-Yen Yeh, Pardeep Thandi
BACKGROUND: The efficacy, safety, opioid-sparing effects, and cost-benefit analyses of intravenous (IV) acetaminophen (APAP) in treating renal colic remain controversial. STUDY QUESTION: To evaluate the safety, efficacy, opioid-sparing effects, and cost-benefits of IV APAP in patients who present with renal colic in the emergency department (ED). DATA SOURCES: We systematically searched PubMed (January 1970 to April 2016). STUDY DESIGN: Randomized controlled trials which evaluated IV APAP for renal colic in the ED were eligible...
October 24, 2016: American Journal of Therapeutics
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