Journal of the History of the Neurosciences

After the end of the Spanish Civil War (1936-1939), an estimated 1,000 patients presented with lathyrism due to their excessive and prolonged consumption of grasspea ( Lathyrus sativus L.) against the backdrop of poverty, drought, and famine. Based on 68 scientific communications between 1941 and 1962 by qualified medical professionals, the disease emerged in different geographical locations involving selective populations: (1) farmers from extensive areas of central Spain, traditionally producers and consumers of grasspea; (2) immigrants in the industrial belt of Catalonia and in the Basque Country, areas with little or no production of grasspea, which was imported from producing areas; (3) workers in Galicia, an area where the legume is neither produced nor consumed, who were seasonally displaced to high-production areas of grasspea in Castille; and (4) inmates of overcrowded postwar Spanish prisons...

Efforts to treat epileptic seizures likely date back to primitive, manmade skull openings or trephinations at the site of previous scalp or skull injuries. The purpose may have been the release of "evil spirits," removal of "cerebral excitement," and "restoral of bodily and intellectual functions." With progressive discoveries in brain function over the past 100 to 300 years, the cerebral cortical locations enabling voluntary movements, sensation, and speech have been well delineated. The locations of these functions have become surgical targets for the amelioration of disease processes...

On October 20, 1924, at the Waldorf-Astoria Hotel in New York City, two medical graduates of the University of Sydney delivered the John B. Murphy Oration to the American College of Surgeons on the topic of sympathetic ramisection for the treatment of spastic paralysis. The surgery was regarded as a triumph. The triumph, however, was short-lived, when one of the speakers, John Irvine Hunter, a promising anatomist, died prematurely. Norman Royle, an orthopedic surgeon, continued the research program and continued to perform these operations...

In 1949, William Stewart Alexander (1919-2013), a young pathologist from New Zealand working in London, reported the neuropathological findings in a 15-month-old boy who had developed normally until the age of seven months, but thereafter had progressive enlargement of his head and severe developmental delay. The most striking neuropathological abnormality was the presence of numerous Rosenthal fibers in the brain. The distribution of these fibers suggested to Alexander that the primary pathological change involved astrocytes...

No abstract text is available yet for this article.

The development of the brain sciences ( Hirnforschung ) in the Max Planck Society (MPG) during the early decades of the Federal Republic of Germany (FRG) was influenced by the legacy of its precursor institution, the Kaiser Wilhelm Society for the Advancement of Science (KWG). The KWG's brain science institutes, along with their intramural psychiatry and neurology research programs, were of considerable interest to the Western Allies and former administrators of the German science and education systems in their plans to rebuild the extra-university research society-first in the British Occupation Zone and later in the American and French Occupation Zones...

To further our understanding of the transformations of the modern, globalized world, historical research concerning the twentieth century must acknowledge the tremendous impact that science and technology exerted and continue to exert on political, economic, military, and social developments. To better comprehend a global history of science, it is also crucial to include Germany's most prominent research organization: The Max Planck Society for the Advancement of Science (MPG). Despite the existence of numerous institute chronicles and selected anniversary editions, the overall development of the MPG-historically situated in more than 80 institutes with more than 250 research service departments (of which approximately 50 have reached into the wider field of neuroscience, behavioral science, and cognitive science)-it remains largely terra incognita from a scholarly perspective...

The famous discussion of Scythian cross-dressers in Hippocrates' Airs Waters Places ( Aer .) 22 puzzled perhaps most medieval and Renaissance medical authorities. The text wrestled with a pre-Hippocratic, encephalocentric theory of spermatogenesis. Modern reception of the convoluted hypothesis put forward here gradually distilled three etiologies of failing virility: impotence, subfertility, and unmanliness. A gradual shift is discernable from increasingly Galenic neuro-andrological theories (sixteenth century) to neuropsychiatric (late-seventeenth through eighteenth century), phrenological and psychopathological (early- and late-nineteenth century), and finally early psycho-endocrinological (early-twentieth century) ideas about masculinity...

Between 1882 and 2016, the medical literature offered a variety of etiologic hypotheses to explain Joan of Arc's voices, visions, and unwavering belief that she was the instrument of God. Although Joan lived from 1412 to 1431, there is extensive primary documentation of her life, including transcripts of her testimony during the Trial of Condemnation. Once this source material was compiled and made available, physician-authors began to theorize about Joan's neuropsychiatric symptoms in the context of her remarkable achievements...

This article examines the divisive reception history of American psychiatrist and neurologist Alexander McLane Hamilton's physiognomy publication, Types of Insanity (1883). By analyzing 23 book reviews published in late-nineteenth-century medical journals, the authors present a bibliographic case study that traces the mixed professional reactions to Hamilton's work, thus revealing the fraught nature of physiognomy in the American medical community. In effect, the authors argue that the interprofessional disagreements that emerged among journal reviewers indicate the nascent efforts of psychiatrists and neurologists to oppose physiognomy in the interest of professionalization...

No abstract text is available yet for this article.

The cell doctrine-the theory of ventricular localization of the mental faculties-includes Galen's idea of a locking or valve mechanism between the middle and the rear ventricle. The anatomical substrate was the vermiform epiphysis, known today as the vermis cerebelli . This entity played a significant role in brain physiology even though its appearance, texture, and location changed over time. This article tells the story of the "worm's" transformation from Galen to Vesalius and beyond. Until the time of Albertus Magnus (c...

No abstract text is available yet for this article.

The amygdaloid complex is a crucial component of the basal forebrain that participates in the modulation of many homeostatic functions, emotional behaviors, and learning. These features require a widespread pattern of connections with several brain structures. In the past, the amygdaloid complex was divided into corticomedial and basolateral groups. The existence of a neuronal continuum linking the central amygdaloid nucleus to the lateral bed nucleus of stria terminalis through the subpallidal area was first revealed by José de Olmos (1932-2008) with the aid of his cupric-silver technique...

In 1985, historian Götz Aly published an article showing that the director of the Kaiser Wilhelm Institute for Brain Research, neuropathologist Julius Hallervorden (1882-1965), had acquired brains of Nazi "euthanasia" victims and brain specimens of at least 33 children gassed at the Brandenburg killing center on October 28, 1940, which were still kept by the Max Planck Institute for Brain Research. Aly criticized that the Max Planck Society had suppressed articles by journalist Hermann Brendel in the 1970s claiming that institutes of the Kaiser Wilhelm Society had conducted brain research within the framework of "euthanasia...

In most parts of the developed world today, the neurological diagnosis of poliomyelitis is discussed only as a historical curiosity. For decades an epidemic cause for lameness and paralysis in infected children, reported cases of polio plummeted following the introduction of effective vaccines against the causative virus in the 1950s and 1960s. Much has been written of the trials and successes of the Global Polio Eradication Initiative, but little is generally known about how the disease was originally named...

Ernst Brücke was one of the most influential figures in Sigmund Freud's life and work. Freud studied under him for around six years during his student years, and he never turned his back on Brücke's fundamental teachings. Brücke was a member of the strictly materialist and reductionist movement called the School of Helmholtz. This article will interpret how this physiological movement influenced Freud's psychoanalysis and how its understanding of science was embedded in Freud's theory. For this purpose, I will focus on the relationship between Brücke and Freud, and then will demonstrate how Brücke's influence appears in Freud's psychoanalytical theory...

No abstract text is available yet for this article.

Albert Wojciech Adamkiewicz (1850-1821) was a Polish neurologist and researcher who is best known for his description of the so-called Adamkiewicz-artery. In contrast to his achievements in neurology, his research in psychiatry from his time in Vienna (1891-1921) is commonly overlooked. We examined all titles of his publications from 1891 to 1921 and provided a close reading of those works that were related to his research on the neural basis of mental phenomena and disorders. We demonstrate that, in later stages of his scientific career, Adamkiewicz critically engaged with contemporary positions in psychiatry and the psychogenic explanation of mental disorders...

Edward Henry Sieveking (1816-1904) was a professionally successful and well respected nineteenth-century London physician who, over the span of some half a century, continuously held appointment to British royalty, including Queen Victoria and King Edward VII. In 1858, he published a monograph On Epilepsy and Epileptiform Seizures , with a second edition in 1861. In both editions, he described an entity cephalalgia e pileptica that comprised the occurrence of headache in association with phenomena that resembled the premonitory symptom of some epileptic seizures...