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Journal of Orthopaedic Surgery

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https://www.readbyqxmd.com/read/30442072/bmp-7-smad-expression-in-dedifferentiated-schwann-cells-during-axonal-regeneration-and-upregulation-of-endogenous-bmp-7-following-administration-of-pth-1-34
#1
Naoki Kokubu, Masaya Tsujii, Koji Akeda, Takahiro Iino, Akihiro Sudo
PURPOSE: To determine the expression and distribution of bone morphogenetic protein (BMP)-7 and related molecules during peripheral nerve regeneration and to assess whether administration of parathyroid hormone (PTH) drug (1-34) potentiates the intrinsic upregulation of BMP-7/Smad signaling. METHODS: The rat sciatic nerves were crushed with an aneurysm clip resulting in axonal degeneration. In the normal nerve, and at 1, 2, 4, and 8 weeks after injury, BMP-7, BMP receptors, p-Smad 1/5/8, and Noggin, the endogenous BMP antagonist, were evaluated...
May 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/30428758/treatment-of-benign-and-borderline-bone-tumors-with-combined-curettage-and-bone-defect-reconstruction
#2
Peter F Horstmann, Werner H Hettwer, Michael M Petersen
PURPOSE: The management of bone defects following simple curettage of bone tumors is controversial and in light of the numerous emerging substitutes for bone grafts, we wished to review and report our experience with the use of cancellous allograft bone in the treatment of benign and borderline bone tumors. METHODS: We reviewed the medical records of 164 consecutive patients with benign or borderline bone tumors treated with simple curettage at our orthopedic oncology center between 2009 and 2013...
May 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/30415603/outcomes-of-expedited-rotator-cuff-surgery-in-injured-workers-impact-of-pathology-on-readiness-for-return-to-work
#3
Gargi Singh, Helen Mann, Helen Razmjou
OBJECTIVES: The objectives of this study were to (1) examine the overall recovery and satisfaction following an expedited rotator cuff (RC) decompression or repair at 3-6 months and (2) explore group differences (repair vs. decompression) in demographics, clinical, disability, and psychosocial factors. METHODS: This was a prospective longitudinal study of injured workers whose surgery was expedited. The outcome measures were Quick disabilities of the arm, shoulder, and hand ( QuickDASH), the Hospital Anxiety and Depression Scale (HADS), the readiness for return to work (RRTW) scale, and satisfaction with surgery and overall recovery...
May 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/30415598/treatment-modalities-for-hip-and-knee-osteoarthritis-a-systematic-review-of-safety
#4
Osama Aweid, Zakir Haider, Abdel Saed, Yegappan Kalairajah
Current guidelines on the management of hip and knee osteoarthritis (OA) do not compare safety of treatment modalities. We therefore systematically reviewed 20 studies investigating mortality and serious complications of both medical and surgical treatments for hip and knee OA using PubMed, Scopus, Web of Knowledge and Google Scholar. Mortality was the highest for naproxen (hazard ratio (HR) = 3 (1.9, 4.6)) and lowest for total hip replacement (relative risk (RR) = 0.7 (0.7, 0.7)). Highest gastrointestinal complications were reported for diclofenac (odds ratio (OR) = 4...
May 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/30369289/polyethylene-in-total-knee-arthroplasty-where-are-we-now
#5
Spencer K Wilhelm, Jacob L Henrichsen, Matthew Siljander, Drew Moore, Mark Karadsheh
Polyethylene (PE) remains the gold standard for the articulating surface in hip and knee arthroplasty. To increase arthroplasty longevity and improve wear resistance, newer versions of PE have been designed with resultantly different wear properties. Highly cross-linked polyethylene (HXLPE) is used in total hip arthroplasty with excellent outcomes; however, its use in total knee arthroplasty (TKA) remains conflicting. This review summarizes biomechanical and wear properties, clinical outcomes, and cost of polyethylene inserts in TKA...
May 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/30352547/the-efficiency-of-the-posterior-only-approach-using-shaped-titanium-mesh-cage-for-the-surgical-treatment-of-spine-tuberculosis-in-children-a-preliminary-study
#6
Hongqi Zhang, Qiang Guo, Yunjia Wang, Chaofeng Guo, Mingxing Tang
PURPOSE: The study aimed to evaluate the efficiency of the posterior-only approach using shaped titanium mesh cage for surgical treatment of spinal tuberculosis (TB) in children. METHODS: Between January 2011 and July 2013, 22 children with a single motion spinal segment involved, including 10 with thoracic, 4 with thoracolumbar, and 8 with lumbar, were enrolled in the study. The patients were treated by the posterior-only approach using the shaped titanium mesh cages...
May 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/30352544/obesity-and-recovery-of-muscle-strength-after-anterior-cruciate-ligament-reconstruction-in-pediatric-patients
#7
R Jay Lee, Adam Margalit, Afam Nduaguba, Melissa A Gunderson, Lawrence Wells
PURPOSE: To explore factors influencing muscle strength after anterior cruciate ligament (ACL) reconstruction (ACLR) in pediatric patients. We hypothesized that obesity/overweight, autograft hamstring tendon, and concomitant injuries would be associated with slower muscle recovery. METHODS: We retrospectively reviewed the records of pediatric ACLR patients during a 3-year period. Muscle recovery was defined as ≥85% of peak torque compared with the contralateral side...
May 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/30352543/is-the-alignment-guide-technique-in-total-hip-arthroplasty-sufficient-for-accurate-cup-positioning-with-a-modified-watson-jones-approach
#8
Junya Yoshitani, Takuya Nakamura, Yoshinobu Maruhashi, Noriyuki Hashimoto, Takeshi Sasagawa, Kenichi Ueshima, Kiyonobu Funaki
PURPOSE: Cup setting with only an alignment guide has been reported to be inaccurate in the lateral decubitus position in total hip arthroplasty (THA). We assessed the accuracy of cup positioning using only the alignment guide technique via a modified Watson Jones approach in the lateral decubitus position. METHODS: Two hundred hips of 189 patients underwent THA from October 2014 to September 2016 via a modified Watson Jones approach. In the final sample, 181 hips of 171 patients (35 males, 136 females) were included in this investigation...
May 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/30352541/the-accolade-tmzf-stem-fulfils-the-demands-of-modern-stem-design-minimum-5-year-survival-in-a-cohort-of-937-patients
#9
Joost Aam van den Hout, Koen Lm Koenraadt, Robert Wagenmakers, Stefan Bt Bolder
PURPOSE: Modern hip stem design includes a prosthesis that has a predictable outcome in all total hip arthroplasty (THA) patients, regardless of approach, surgeon or patient characteristics. Introduction without a learning curve and, in cases of problems, the possibility for a simple revision are other prerequisites. The purpose of this study is to evaluate whether the Accolade TMZF stem (Stryker Orthopedics, Mahwah, New Jersey, USA) is suitable to fulfil these demands. We report our mid-term survival of the Accolade TMZF hip stem in all patients from the first implantation at our institute...
May 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/30352539/visualization-of-walking-speed-variation-induced-synchronized-dynamic-changes-in-lower-limb-joint-angles-and-activity-of-trunk-and-lower-limb-muscles-with-a-newly-developed-gait-analysis-system
#10
Kousei Miura, Hideki Kadone, Masao Koda, Keita Nakayama, Hiroshi Kumagai, Katsuya Nagashima, Kentaro Mataki, Kengo Fujii, Hiroshi Noguchi, Toru Funayama, Tetsuya Abe, Kenji Suzuki, Masashi Yamazaki
PURPOSE: To evaluate a newly developed system for dynamic analysis of gait kinematics and muscle activity. METHODS: We recruited 10 healthy men into this study. Analyses of three-dimensional motion and wireless surface electromyogram (EMG) were integrated to achieve synchronous measurement. The participants walked continuously for 10 min under two conditions: comfortable and quick pace. Outcome measures were joint angles of the lower limbs determined from reflective markers and myoelectric activity of trunk and lower limbs determined from EMG sensors, comparing comfortable and quick gait pace...
May 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/30352524/do-the-dynamic-stress-mobility-radiographs-predict-the-postoperative-vertebral-height-restoration-kyphosis-correction-and-cement-volume-injected-after-vertebroplasty-for-osteoporotic-thoracolumbar-vertebral-fractures-with-intravertebral-cleft
#11
Chee Kidd Chiu, Kulathunga Arachchige Lisitha, Dahlia Munchar Elias, Voon Wei Yong, Chris Yin Wei Chan, Mun Keong Kwan
BACKGROUND: This prospective clinical-radiological study was conducted to determine whether the dynamic mobility stress radiographs can predict the postoperative vertebral height restoration, kyphosis correction, and cement volume injected after vertebroplasty. METHODS: Patients included had the diagnosis of significant back pain caused by osteoporotic vertebral compression fracture secondary to trivial injury. All the patients underwent routine preoperative sitting lateral spine radiograph, supine stress lateral spine radiograph, and supine anteroposterior spine radiograph...
May 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/30343651/ceftaroline-fosamil-laden-allograft-a-new-modality-in-reducing-infection
#12
Vivek Ajit Singh, Lim Han Sim, Amber Haseeb, Cindy Teh Shuan Ju
PURPOSE: Allograft infection remains the greatest challenge in orthopaedic reconstructive surgery especially methicillin-resistant Staphylococcus aureus (MRSA). This risk can be minimized with the use of antibiotic laden allograft (ALA) via iontophoresis. Ceftaroline fosamil (CF) is an advanced-generation cephalosporin, an alternative treatment for MRSA infections. Its antibacterial activity and safety profile are better than vancomycin. CF iontophoresed bone has not been used before...
May 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/30296889/does-short-term-weekly-teriparatide-improve-healing-in-unstable-intertrochanteric-fractures
#13
Seung-Ju Kim, Hyun-Soo Park, Dong-Woo Lee, Jae-Won Lee
Slow recovery after hip fracture has been associated with negative consequences. Thus, there is medical need to improve healing and functional recovery after intertrochanteric fracture. The aim of this study was to measure whether short-term teriparatide would improve healing in intertrochanteric fractures after internal fixation as measured by (1) clinical scores, (2) radiographic fracture healing, and (3) complication rates. We retrospectively reviewed 96 patients (average age, 82 years) who underwent closed reduction and internal fixation with proximal femoral nail (PFN) for unstable intertrochanteric fractures between 2014 and 2016...
May 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/30295168/total-contact-casting-versus-traditional-dressing-in-diabetic-foot-ulcers
#14
Biswajit Sahu, Alok Prusty, Barsha Tudu
This study compared the treatment of total contact casting (TCC) with traditional dressing treatment (TD) in the management of neuropathic diabetic plantar ulcers. Thirty-one patients with plantar ulcers without any gross infection, osteomyelitis or gangrene were randomly assigned to the TCC group (n = 15) or TD group (n = 16). In the experimental group, TCC was applied on the initial visit and subjects were instructed to limit ambulation to one-third of their usual activity. Subjects in the control group (TD) were prescribed dressing changes and were advised against bearing weight on the involved extremity...
May 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/30295139/platelet-rich-plasma-decreases-fibroblastic-activity-and-woven-bone-formation-with-no-significant-immunohistochemical-effect-on-long-bone-healing-an-experimental-animal-study-with-radiological-outcomes
#15
İbrahim Deniz Canbeyli, Rahmi Can Akgun, Orcun Sahin, Aysen Terzi, İsmail Cengiz Tuncay
PURPOSE: This study aimed to analyze the immunohistochemical effect of platelet-rich plasma (PRP) on healing of long-bone fractures in terms of bone morphogenetic protein-2 (BMP-2), vascular endothelial growth factor (VEGF), the Ki-67 proliferation index, and radiological and histological analyses. METHODS: Sixteen adult rabbits, whose right femoral diaphysis was fractured and fixed with Kirschner wires, were randomly divided into two groups, control and PRP (groups A and B, respectively)...
May 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/30295136/risk-of-patella-baja-after-opening-wedge-high-tibial-osteotomy
#16
Shuhei Otsuki, Tomohiko Murakami, Yoshinori Okamoto, Kosuke Nakagawa, Nobuhiro Okuno, Hitoshi Wakama, Masashi Neo
PURPOSE: Medial opening-wedge high tibial osteotomy (OWHTO) induces a lower patellar position, and the subsequent degree of patellar movement may not be predicted preoperatively. The purpose of this study was to clarify the relationship between preoperative and postoperative patellar height based on the correction angle of OWHTO and to create a formula to predict the appearance of patella baja following OWHTO. MATERIALS AND METHODS: Seventy-five knees with varus knee osteoarthritis treated with OWHTO were included in this study...
May 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/30295134/changes-of-mediolateral-soft-tissue-gaps-in-total-knee-arthroplasty-after-suturing-medial-extensor-in-navigation
#17
Seung Bum Chae, Myung Rae Cho, Jae Bum Kwon, Jae Hyuk Lee, Won Kee Choi
PURPOSE: Aim is to investigate the changes of mediolateral soft tissue gaps in total knee arthroplasty (TKA) after suturing medial extensor. METHODS AND MATERIALS: We compared the differences of medial and lateral gap values that were shown by the computer navigation at 0°, 45°, 90°, and 120° knee flexion during patella in situ and during patella repaired by a towel clip on two constant sites. Fifty consecutive knees (43 patients) scheduled for TKA due to varus knee osteoarthritis, from February 2017 to May 2017, were enrolled in this prospective study...
May 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/30295123/results-of-tenorrhaphy-with-early-rehabilitation-for-acute-tear-of-achilles-tendon
#18
Chang Hyun Ryu, Ho Seong Lee, Sang Gyo Seo, Ho Yeon Kim
BACKGROUND: For the treatment of acute Achilles tendon rupture, early rehabilitation after surgical repair is believed to be a useful method. The purpose of this study was to evaluate the outcome of open tenorrhaphy followed by early rehabilitation. METHODS: A total of 112 patients who underwent open repair and early rehabilitation for acute Achilles tendon rupture from January 2003 to March 2015 were retrospectively reviewed. These 112 patients (80 men, 32 women) had an average age of 43...
May 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/30278819/outcomes-of-an-accelerated-nonsurgical-management-protocol-for-hip-fractures-in-the-elderly
#19
Wei Xiang Lim, Ernest Beng Kee Kwek
The majority of hip fractures in elderly patients are managed surgically with superior outcomes. However, for patients who refuse surgery or are deemed medically unfit, traction used to be the mainstay of nonsurgical treatment, which is associated with prolonged hospitalization and inpatient complications from immobility. This study, therefore, aims to evaluate the outcomes of an early wheelchair mobilization protocol as an alternative nonsurgical treatment option. This is a retrospective study of 87 elderly patients who were managed nonsurgically for their hip fractures over a 1-year period...
May 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/30278809/a-three-dimensional-virtual-morphometry-study-of-the-sigmoid-notch-of-the-distal-radius
#20
Sachin Shivdas, M S Hashim, T Sara Ahmad
PURPOSE: Our primary objectives were to create a reliable, noninvasive method for three-dimensional morphometry of deep bony parameters within the sigmoid notch of the distal radius, to identify its morphological patterns, and to identify any significant variation between the left and the right wrists. Our secondary objectives were to obtain morphometric values that could represent our population and to identify any possible ethnic variations. METHODS: Computed tomography scans of 102 wrists from 51 healthy individuals were analyzed using a virtualization software...
May 2018: Journal of Orthopaedic Surgery
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